Endometriosis of Ovary disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: END011 MIFTS: 41	Endometriosis of Ovary Categories: Endocrine diseases, Reproductive diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Endometriosis of Ovary

MalaCards integrated aliases for Endometriosis of Ovary:

Name: Endometriosis of Ovary ¹² ¹⁵ ⁷⁴

Ovarian Endometriosis ¹² ¹⁷

Classifications:

MalaCards categories:
Anatomical: Reproductive diseases Endocrine diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Diseases of the genitourinary system

Noninflammatory disorders of female genital tract

Endometriosis

Endometriosis of ovary

External Ids:

Disease Ontology ¹² DOID:11432

ICD9CM ³⁶ 617.1

NCIt ⁵¹ C27628

SNOMED-CT ⁶⁹ 31007005

ICD10 ³⁴ N80.1

EFO ¹⁷ EFO_1000418

UMLS ⁷⁴ C0156344

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Summaries for Endometriosis of Ovary

Disease Ontology : ¹² A female reproductive system disease characterized by the growth of endometrial tissue that is located in the ovary.

MalaCards based summary : Endometriosis of Ovary, also known as ovarian endometriosis, is related to ovarian clear cell carcinoma and ovary adenocarcinoma. An important gene associated with Endometriosis of Ovary is ESR2 (Estrogen Receptor 2), and among its related pathways/superpathways are Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2 and Plasma membrane estrogen receptor signaling. The drugs Anastrozole and Goserelin have been mentioned in the context of this disorder. Affiliated tissues include ovary, uterus and endothelial.

Wikipedia : ⁷⁷ Endometrioma is the presence of endometrial tissue in and sometimes on the ovary. It is the most common... more...

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Related Diseases for Endometriosis of Ovary

Diseases related to Endometriosis of Ovary via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)

#	Related Disease	Score	Top Affiliating Genes
1	ovarian clear cell carcinoma	30.1	ARID1A HNF1B
2	ovary adenocarcinoma	29.9	ARID1A HNF1B
3	ovarian cancer 1	29.9	ARID1A HNF1B
4	endometriosis	11.0
5	clear cell adenocarcinoma	10.3	ARID1A HNF1B
6	extrapelvic endometriosis	10.3
7	postmenopausal atrophic vaginitis	10.3	ESR1 ESR2
8	vaginitis	10.3	ESR1 ESR2
9	progesterone-receptor positive breast cancer	10.3	ESR1 ESR2
10	progesterone resistance	10.3	ESR1 ESR2
11	gender identity disorder	10.2	ESR1 ESR2
12	estrogen excess	10.2	ESR1 ESR2
13	dental fluorosis	10.2	ESR1 ESR2
14	lobular neoplasia	10.2	ESR1 ESR2
15	ovarian cancer	10.2
16	sarcoma	10.2
17	adenocarcinoma	10.2
18	ovarian clear cell adenocarcinoma	10.2	ARID1A ESR2 HNF1B
19	estrogen resistance	10.1	ESR1 TRERF1
20	female reproductive system disease	10.1	ARID1A ESR1 ESR2
21	malignant ovarian surface epithelial-stromal neoplasm	10.1	ARID1A ESR1 HNF1B
22	ovary epithelial cancer	10.1	ARID1A ESR1 HNF1B
23	squamous cell carcinoma	10.1
24	infertility	10.1
25	hydatidiform mole, recurrent, 1	10.0
26	adenomyosis	10.0
27	ectopic pregnancy	10.0
28	ulceration of vulva	10.0
29	leiomyoma	10.0
30	acromegaly	10.0
31	gestational trophoblastic neoplasm	10.0
32	arthropathy	10.0
33	adenoma	10.0
34	leiomyoma, uterine	9.8
35	joint disorders	9.8
36	persistent mullerian duct syndrome	9.8
37	pelvic inflammatory disease	9.8
38	ovarian disease	9.8
39	adenofibroma	9.8
40	endometrial adenocarcinoma	9.8
41	cystadenocarcinoma	9.8
42	serous cystadenocarcinoma	9.8
43	teratoma	9.8
44	endometrial stromal sarcoma	9.8
45	spindle cell sarcoma	9.8
46	carcinosarcoma	9.8
47	leiomyomatosis	9.8
48	intestinal disease	9.8
49	clear cell adenofibroma	9.8
50	ovarian germ cell teratoma	9.8

Comorbidity relations with Endometriosis of Ovary via Phenotypic Disease Network (PDN):

Fallopian Tube Endometriosis

Myofibroma

Graphical network of the top 20 diseases related to Endometriosis of Ovary:

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Symptoms & Phenotypes for Endometriosis of Ovary

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Drugs & Therapeutics for Endometriosis of Ovary

Drugs for Endometriosis of Ovary (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Anastrozole

Approved, Investigational

Phase 4

120511-73-1

2187

Synonyms:

.alpha.,alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

1,3-benzenediacetonitrile, a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)

120511-73-1

2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)

2,2'-(5-(1H-1,2,4-Triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)

2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)

2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)

2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile

a,a,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

AC1L1D49

AC-4234

alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

alpha,alpha,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

anastrazole

Anastrazole

Anastrole

Anastrozol

anastrozole

Anastrozole

Anastrozole (JAN/USAN/INN)

Anastrozole [USAN:INN:BAN]

Arimidex

Arimidex (TN)

Arimidex (Zeneca)

Arimidex, Anastrozole

Asiolex

Astra brand of anastrozole

Astra brand OF anastrozole

AstraZeneca brand of anastrozole

AstraZeneca brand OF anastrozole

C08159

C090450

C17H19N5

CHEBI:2704

CHEMBL1399

CID2187

CPD000466301

D00960

DB01217

HMS2052M11

HMS2089N10

HSDB 7462

I06-0021

ICI D1033

ICI-D 1033

ICI-D1033

LS-29563

MLS000759396

MLS001424217

MolPort-005-933-078

NCGC00164619-01

NSC719344

S1188_Selleck

SAM001246525

SBB066057

SMR000466301

UNII-2Z07MYW1AZ

ZD 1033

ZD1033

ZD-1033

Zeneca brand of anastrozole

Zeneca brand OF anastrozole

Zeneca ZD 1033

ZINC00000941

α,α,alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

Goserelin

Approved

Phase 4

65807-02-5

5311128 47725

Synonyms:

(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

AC1NSK1T

Acetate, goserelin

CID5311128

goserelin

Goserelin

Goserelin acetate

Goserelina

HMS2089D16

HS-2015

ICI 118

ICI-118630

ICI-118630Zoladex

MolPort-006-823-831

ZD-9393

Zoladex

Aromatase Inhibitors

Phase 4

Estrogen Receptor Antagonists

Phase 4

Estrogen Antagonists

Phase 4

Hormones

Phase 4,Not Applicable

Steroid Synthesis Inhibitors

Phase 4

Antineoplastic Agents, Hormonal

Phase 4,Phase 2

Hormone Antagonists

Phase 4,Not Applicable

Estrogens

Phase 4

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4,Not Applicable

Medroxyprogesterone acetate

Approved, Investigational

Phase 2

71-58-9

Synonyms:

(6α)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione

17-Acetoxy-6α-methylprogesterone

17α-hydroxy-6α-methylprogesterone acetate

6-alpha-Methyl-17-alpha-acetoxyprogesterone

6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate

6α-Methyl-17-acetoxy progesterone

6α-Methyl-17α-hydroxyprogesterone acetate

6α-Methyl-4-pregnene-3,20-dion-17α-ol acetate

Medroxyacetate progesterone

Medroxyprogesterone 17-acetate

Methylacetoxyprogesterone

Metigestrona

MPA

Axitinib

Approved, Investigational

Phase 1, Phase 2

319460-85-0

6450551

Synonyms:

319460-85-0

790713-39-2

AC-1539

AC1O51X3

AG 013736

AG013736

AG-013736

AG-013736, Axitinib

AG-13736

axitinib

Axitinib

Axitinibum

C503983

CID6450551

EC-000.2322

I14-1971

Inlyta

INLYTA

MolPort-006-392-413

N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide

N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide

S1005_Selleck

ST51054130

UNII-C9LVQ0YUXG

ZINC03816287

afatinib

Approved

Phase 1, Phase 2

850140-72-6, 439081-18-2

10184653

Medroxyprogesterone

Phase 2

520-85-4

10631

Synonyms:

(6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione

(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

17 alpha Hydroxy 6 alpha methylprogesterone

17 alpha Hydroxy 6 alpha Methylprogesterone

17 alpha-Hydroxy-6 alpha-methylprogesterone

17 alpha-Hydroxy-6 alpha-Methylprogesterone

17.alpha.-Hydroxy-6.alpha.-methylprogesterone

17a-Hydroxy-6a-methylprogesterone

17alpha-Hydroxy-6alpha-methyl-4-pregnene-3,20-dione

17alpha-Hydroxy-6alpha-methylprogesterone

17-Hydroxy-6.alpha.-methylprogesterone

17-Hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione

17-Hydroxy-6alpha-methylprogesterone

17-Hydroxy-6a-methyl-pregn-4-ene-3,20-dione

17-Hydroxy-6a-methylprogesterone

17-Hydroxy-6α-methyl-pregn-4-ene-3,20-dione

17-Hydroxy-6α-methylprogesterone

17α-hydroxy-6α-methylprogesterone

4-08-00-02211 (Beilstein Handbook Reference)

46411_FLUKA

46411_RIEDEL

520-85-4

6.alpha.-Methyl-17.alpha.-hydroxyprogesterone

6alpha-Methyl-17alpha-hydroxyprogesterone

6-alpha-Methyl-17-alpha-hydroxyprogesterone

6alpha-Methyl-4-pregnen-17alpha-ol-3,20-dione

6alpha-Methyl-5-pregnen-17alpha-ol-3,20-dione

6a-Methyl-17a-hydroxyprogesterone

6a-Methyl-4-pregnen-17a-ol-3,20-dione

6-Dihydromegestrol

6α-methyl-17α-hydroxyprogesterone

6α-methyl-4-pregnen-17α-ol-3,20-dione

AC-14528

AC1L1VM7

Adgyn medro

Adgyn Medro

Aragest

Aragest 5

Asconale

BRN 2510965

C07119

CBP-1011

CHEBI:6715

CHEMBL1390

CID10631

Clinofem

Clinovir

Colirest

CPD000058769

Cycrin

D008525

D08166

DB00603

Depo-Clinovir

Depo-Prodasone

Depo-Progestin

Depo-Promone

depo-Provera

depo-Subq provera 104

Depot-Medroxyprogesterone acetate

DMPA

EINECS 208-298-6

Farlutal

Farlutal inyectable

Farlutal inyectable (TN)

Farlutin

Gestapuran

g-Farlutal

G-Farlutal

Hematrol

HMS2052A13

HSDB 3114

Hydroxymethylprogesterone

Hysron

Indivina

LMST02030176

LS-118713

Lunelle

Lutopolar

Lutoral

M6013_SIGMA

MAP

Med-Pro

Medroprogesterone Acetate

Medrossiprogesterone

Medrossiprogesterone [Dcit]

Medrossiprogesterone [DCIT]

Medroxiprogesterona

Medroxiprogesterona [INN-Spanish]

Medroxiprogesteronum

Medroxyprogesteron

Medroxyprogesteron acetate

medroxyprogesterone

Medroxyprogesterone (INN)

Medroxyprogesterone [INN:BAN]

Medroxyprogesterone acetate

Medroxyprogesterone strakan brand

Medroxyprogesterone Strakan Brand

Medroxyprogesteronum

Medroxyprogesteronum [INN-Latin]

Meprate

Methylhydroxyprogesterone

Metigestrona

MLS000069571

MLS001076098

MolPort-005-934-866

MPA Gyn 5

Nadigest

NCGC00023064-04

Nidaxin

Novo-Medrone

NSC 27408

NSC27408

Oragest

Perlutex

Perlutex Leo

Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)- (9CI)

Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6-alpha)- (9CI)

Prodasone

Progestalfa

Progevera

Provera

Proverone

Ralovera

Repromap

Repromix

SAM001246906

Sirprogen

SMR000058769

Sodelut G

ST082267

Strakan brand OF medroxyprogesterone

Strakan Brand of Medroxyprogesterone

U 8840

UNII-HSU1C9YRES

Veramix

ZINC05763835

Contraceptive Agents

Phase 2

Contraceptive Agents, Male

Phase 2

Protein Kinase Inhibitors

Phase 1, Phase 2

Pentetic acid

Approved

Not Applicable

67-43-6

Edetic Acid

Approved, Vet_approved

Not Applicable

62-33-9, 60-00-4

6049

Synonyms:

(ethylenedinitrilo)Tetraacetate, ion(4-)

(ethylenedinitrilo)tetraacetic acid, ion(4−)

(ethylenedinitrilo)Tetraacetic acid, ion(4-)

{[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetate

{[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid

{[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetIC ACID

2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate

2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid

Acid, edetic

Acid, ethylenediaminetetraacetic

Acid, ethylenedinitrilotetraacetic

acide edetique

Acide edetique

Acide ethylenediaminetetracetique

acido Edetico

Acido edetico

Acidum edeticum

CaEDTA

Calcitetracemate, disodium

Calcium disodium edetate

Calcium disodium versenate

Calcium tetacine

Chelaton 3

Chromium edta

Copper edta

Coprin

Dicobalt edta

Dinitrilotetraacetate, disodium ethylene

Dinitrilotetraacetate, ethylene

Disodium calcitetracemate

Disodium edta

Disodium ethylene dinitrilotetraacetate

Disodium versenate, calcium

Distannous edta

Edathamil

Edetate

Edetate calcium

Edetate calcium disodium

Edetate disodium calcium

Edetate, calcium disodium

Edetates

Edetic Acid

Edetic acid, calcium salt

Edetic acid, calcium, sodium salt

Edetic acid, chromium salt

Edetic acid, dipotassium salt

Edetic acid, disodium salt

Edetic acid, disodium salt, dihydrate

Edetic acid, disodium, magnesium salt

Edetic acid, disodium, monopotassium salt

Edetic acid, magnesium salt

Edetic acid, monopotassium salt

Edetic acid, monosodium salt

Edetic acid, potassium salt

Edetic acid, sodium salt

EDT

EDTA

EDTA, chromium

EDTA, copper

EDTA, dicobalt

EDTA, disodium

EDTA, distannous

EDTA, gallium

EDTA, ion(4-)

EDTA, magnesium disodium

EDTA, potassium

EDTA, stannous

Ethylene dinitrilotetraacetate

Ethylene dinitrilotetraacetate, disodium

Ethylenediaminetetraacetate

Ethylenediaminetetraacetic acid

Ethylenedinitrilotetraacetic acid

Gallium edta

H4EDta

Magnesium disodium edta

N,N'-1,2-ethane diylbis-(N-(carboxymethyl)glycine)

N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine)

N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine)

Potassium edta

Stannous edta

Tetacine, calcium

Tetracemate

Versenate

Versenate, calcium disodium

Versene

Anesthetics

Not Applicable

Coagulants

Not Applicable

Hemostatics

Not Applicable

Follicle Stimulating Hormone

Not Applicable

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis	Completed	NCT00286351	Phase 4	Combined treatment with Arimidex and Zoladex before IVF
2	PGL5001 Proof of Concept Study in Inflammatory Endometriosis	Completed	NCT01630252	Phase 2	PGL5001;Placebo;PGL5001;Placebo;PGL5001
3	Safety, Tolerability and Efficacy of Vaginal Suppositories for Treatment of the Endometriosis	Not yet recruiting	NCT03481842	Phase 1, Phase 2	BIBW2992;Axitinib
4	Somatic Stem Cells in Endometriosis	Unknown status	NCT01412138
5	Impact on Ovarian Reserve According to the Type of Ovarian Endometrioma Excision: Laser Versus Conventional Cystectomy	Completed	NCT03826355	Not Applicable
6	Assessment of Telomerase Activity in Endometrial Tissue and Serum in Endometriosis Patients	Completed	NCT02984774	Not Applicable
7	Artificial Reproductive Techniques (ART) and Progression of Endometriosis Symptoms	Completed	NCT02762461
8	Perinatal Consequences of Endometriosis	Active, not recruiting	NCT02498691	Not Applicable
9	Oxidative Stress Gene Polymorphism and Ovarian Reserve Functione	Not yet recruiting	NCT03682341
10	Ovarian Function After Use of Various Hemostatic Techniques During Treatment for Endometrioma	Not yet recruiting	NCT03430609	Not Applicable

Search NIH Clinical Center for Endometriosis of Ovary

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Genetic Tests for Endometriosis of Ovary

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Anatomical Context for Endometriosis of Ovary

MalaCards organs/tissues related to Endometriosis of Ovary:

⁴²

Ovary, Uterus, Endothelial, Liver, Cervix, Smooth Muscle, Cortex

The Foundational Model of Anatomy Ontology organs/tissues related to Endometriosis of Ovary:

²⁰

The Ovary

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Publications for Endometriosis of Ovary

Articles related to Endometriosis of Ovary:

(show top 50) (show all 249)

#	Title	Authors	Year
1	Aberrant methylation of the IL-12B promotor region contributes to the risk of developing ovarian endometriosis. ( 30865360 )	Zhao W...Li Y	2019
2	Pathogenetic gene changes of eutopic endometrium in patients with ovarian endometriosis. ( 30882467 )	Li L...Lang JH	2019
3	Extra-uterine low grade endometrioid stromal sarcoma arising from ovarian endometriosis: a case report and review of the literature. ( 30723546 )	Efared B...El Fatemi H	2019
4	Metabolomics analysis of follicular fluid in women with ovarian endometriosis undergoing in vitro fertilization. ( 29806498 )	Karaer A...Dogan B	2019
5	Vibrational characterization of granulosa cells from patients affected by unilateral ovarian endometriosis: New insights from infrared and Raman microspectroscopy. ( 30639914 )	Notarstefano V...Giorgini E	2019
6	Analysis of long non-coding RNA expression profiles using RNA sequencing in ovarian endometriosis. ( 29920364 )	Cui D...Xu K	2018
7	Analysis of CARD10 and CARD11 somatic mutations in patients with ovarian endometriosis. ( 29928437 )	Zou Y...Huang OP	2018
8	NR4A1 is Involved in Fibrogenesis in Ovarian Endometriosis. ( 29669342 )	Zeng X...Li Y	2018
9	Ovarian endometriosis: risk factor analysis and prediction of malignant transformation. ( 29725285 )	Zhou Y...Hua KQ	2018
10	A functional promoter polymorphism in interleukin 12B gene is associated with an increased risk of ovarian endometriosis. ( 29738836 )	Zhao W...Kang S	2018
11	Integration analysis of microRNA and mRNA paired expression profiling identifies deregulated microRNA-transcription factor-gene regulatory networks in ovarian endometriosis. ( 29357938 )	Zhao L...Meng Y	2018
12	Novel TRERF1 mutations in Chinese patients with ovarian endometriosis. ( 29393434 )	Cao B...Guo J	2018
13	Factors that Differentiate between Endometriosis-associated Ovarian Cancer and Benign Ovarian Endometriosis with Mural Nodules. ( 28824051 )	Tanase Y...Kobayashi H	2018
14	Pelvic floor muscle assessment on three- and four-dimensional transperineal ultrasound in women with ovarian endometriosis with or without retroperitoneal infiltration: a step towards complete functional assessment. ( 29024196 )	Mabrouk M...Seracchioli R	2018
15	Circular RNA expression in ovarian endometriosis. ( 29334789 )	Shen L...Zhang Y	2018
16	Immunohistochemical Features of O6-Methylguanine-DNA Methyltransferase Expression during Ovarian Endometriosis. ( 29308563 )	Shchegolev AI...Adamyan LV	2018
17	Decreased Expression of HOXA10 May Activate the Autophagic Process in Ovarian Endometriosis. ( 29658437 )	Zheng J...Zheng F	2018
18	Ovarian endometriosis and fertility preservation: a challenge in 2018. ( 29644329 )	Donnez J...Dolmans MM	2018
19	EGFR-mediated matrix metalloproteinase-7 up-regulation promotes epithelial-mesenchymal transition via ERK1-AP1 axis during ovarian endometriosis progression. ( 29558202 )	Chatterjee K...Swarnakar S	2018
20	Perimenopausal management of ovarian endometriosis and associated cancer risk: When is medical or surgical treatment indicated? ( 29551389 )	Vercellini P...Somigliana E	2018
21	The presence of KRAS, PPP2R1A and ARID1A mutations in 101 Chinese samples with ovarian endometriosis. ( 29547736 )	Zou Y...Huang OP	2018
22	The Relationship of Circular RNAs With Ovarian Endometriosis. ( 29490568 )	Xu X...Lang J	2018
23	Identification of Circular RNAs as a Novel Biomarker for Ovarian Endometriosis. ( 29483390 )	Xu XX...Lang JH	2018
24	Comparison of Outcomes of Different Postoperative Hormone Therapy in the Treatment of Ovarian Endometriosis: A Brief Report. ( 29873006 )	Zhu S...Zhang H	2018
25	Novel CTCF mutations in Chinese patients with ovarian endometriosis. ( 29845264 )	Guo J...Zhu B	2018
26	G protein‑coupled estrogen receptor/miR‑148a/human leukocyte antigen‑G signaling pathway mediates cell apoptosis of ovarian endometriosis. ( 29845209 )	He SZ...Sheng YX	2018
27	Risk Factors for Recurrence of Ovarian Endometriosis in Chinese Patients Aged 45 and Over. ( 29786043 )	He ZX...Lang JH	2018
28	Peptidomic Analysis of Endometrial Tissue from Patients with Ovarian Endometriosis. ( 29763921 )	Xue Y...Gu L	2018
29	Mutation analysis of ZP1, ZP2, ZP3 and ZP4 genes in 152 Han Chinese samples with ovarian endometriosis. ( 30611916 )	Zou Y...Huang OP	2018
30	Expression Profile Analysis of Circular RNAs in Ovarian Endometriosis by Microarray and Bioinformatics. ( 30566420 )	Zhang M...Fang X	2018
31	Ovarian endometriosis and infertility: in vitro fertilization (IVF) or surgery as the first approach? ( 30503109 )	Lessey BA...Donnez J	2018
32	Significance of Ovarian Endometriosis on the Prognosis of Ovarian Clear Cell Carcinoma. ( 28930811 )	Park J.Y....Nam J.H.	2017
33	Use of medroxyprogesterone acetate in women with ovarian endometriosis undergoing controlled ovarian hyperstimulation for in vitro fertilization. ( 28931865 )	Guo H....Kuang Y.	2017
34	Silencing of SRA1 Regulates ER Expression and Attenuates the Growth of Stromal Cells in Ovarian Endometriosis. ( 27694140 )	Lin K....Lin J.	2017
35	Endometrioid adenocarcinoma originating simultaneously from endometrium, sites of adenomyosis and ovarian endometriosis: A case report and review of our cancer database. ( 29096350 )	Tashima L...Ito K	2017
36	A case of spontaneous abortion related to ovarian endometriosis in a Golden Retriever dog. ( 28588636 )	Demirel MA	2017
37	Prevalence of high-risk human papillomavirus infection in women with ovarian endometriosis. ( 27928852 )	Heidarpour M...Dashti S	2017
38	Ten Principles for Safe Surgical Treatment of Ovarian Endometriosis. ( 27932268 )	L?pez de la Torre MA...Abrao MS	2017
39	Ovarian endometriosis and vitamin D serum levels. ( 27809683 )	Ciavattini A...Clemente N	2017
40	Association of Endometriosis-Associated Genetic Polymorphisms From Genome-Wide Association Studies With Ovarian Endometriosis in a Chinese Population. ( 27233752 )	Li Y...Kang S	2017
41	Aberrant Methylation of the E-Cadherin Gene Promoter Region in Endometrium and Ovarian Endometriotic Cysts of Patients with Ovarian Endometriosis. ( 27023436 )	Li Y...Kang S	2017
42	Ovarian endometriosis during pregnancy: a series of 53 endometriomas. ( 26482730 )	Bailleux M...Deffieux X	2017
43	Diagnostic performance of human epididymis protein 4 compared to a combination of biophysical and biochemical markers to differentiate ovarian endometriosis from epithelial ovarian cancer in premenopausal women. ( 29027715 )	Nikolova T...Nikolova N	2017
44	Transverse Relaxation Rate of Cyst Fluid Can Predict Malignant Transformation of Ovarian Endometriosis. ( 27646154 )	Yoshimoto C....Kobayashi H.	2016
45	EP27.12: EndometriomaA -A the tip of a pelvic disease: TVS findings associated with an ovarian endometriosis. ( 27647664 )	Exacoustos C....Zupi E.	2016
46	The co-expression of GPER and Gankyrin in ovarian endometriosis and its correlation with the rASRM stages. ( 26193952 )	Zhang C....Zhang Y.	2016
47	Increased Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Patients With Ovarian Endometriosis. ( 26342048 )	Jiang J.F....Sun A.J.	2016
48	Persistent Mullerian Duct Syndrome with Ovarian Endometriosis-A Rare Case Report. ( 27042476 )	Nerune S.M....Mehrotra N.M.	2016
49	Bilateral Ovarian Clear Cell Carcinoma Arising in 17 Year Longstanding History of Bilateral Ovarian Endometriosis. ( 28974971 )	Win T.T....Ismail M.	2016
50	Differential studies of ovarian endometriosis cells from endometrium or oviduct. ( 27424973 )	Liu W...Wang HY	2016

Sources

Genes for Endometriosis of Ovary

Genes related to Endometriosis of Ovary (0 elite genes):

(show all 14)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ESR2	Estrogen Receptor 2	Protein Coding	15.25	DISEASES inferred ¹⁵
2	ARID1A	AT-Rich Interaction Domain 1A	Protein Coding	15.17	DISEASES inferred ¹⁵
3	TRERF1	Transcriptional Regulating Factor 1	Protein Coding	15.13	DISEASES inferred ¹⁵
4	IL12B	Interleukin 12B	Protein Coding	15.06	DISEASES inferred ¹⁵
5	HNF1B	HNF1 Homeobox B	Protein Coding	15.01	DISEASES inferred ¹⁵
6	ESR1	Estrogen Receptor 1	Protein Coding	14.98	DISEASES inferred ¹⁵
7	TTTY4C	Testis-Specific Transcript, Y-Linked 4C	RNA Gene	6.31	DISEASES inferred ¹⁵
8	TTTY8	Testis-Specific Transcript, Y-Linked 8	RNA Gene	6.31	DISEASES inferred ¹⁵
9	TTTY22	Testis-Specific Transcript, Y-Linked 22	RNA Gene	6.31	DISEASES inferred ¹⁵
10	TTTY23	Testis-Specific Transcript, Y-Linked 23	RNA Gene	6.31	DISEASES inferred ¹⁵
11	LPCAT4	Lysophosphatidylcholine Acyltransferase 4	Protein Coding	6.08	DISEASES inferred ¹⁵
12	TTTY5	Testis-Specific Transcript, Y-Linked 5	RNA Gene	6.08	DISEASES inferred ¹⁵
13	TTTY9A	Testis-Specific Transcript, Y-Linked 9A	RNA Gene	6.04	DISEASES inferred ¹⁵
14	TTTY21	Testis-Specific Transcript, Y-Linked 21	RNA Gene	5.96	DISEASES inferred ¹⁵

Sources

Variations for Endometriosis of Ovary

Sources

Expression for Endometriosis of Ovary

Search GEO for disease gene expression data for Endometriosis of Ovary.

Sources

Pathways for Endometriosis of Ovary

Pathways related to Endometriosis of Ovary according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2 ²³	10.7	ESR1 ESR2
2	Plasma membrane estrogen receptor signaling ¹	10.57	ESR1 ESR2
3	MNAR-PELP1 and Estrogen Receptor Interaction ⁶⁵	10.32	ESR1 ESR2
4	Aromatase Inhibitor Pathway (Breast Cell), Pharmacodynamics ⁶²	9.23	ESR1 ESR2

Sources

GO Terms for Endometriosis of Ovary

Biological processes related to Endometriosis of Ovary according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of transcription, DNA-templated	GO:0045893	9.35	ARID1A ESR1 ESR2 HNF1B TRERF1
2	regulation of Wnt signaling pathway	GO:0030111	9.16	ESR1 HNF1B
3	intracellular estrogen receptor signaling pathway	GO:0030520	8.8	ARID1A ESR1 ESR2

Molecular functions related to Endometriosis of Ovary according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	steroid hormone receptor activity	GO:0003707	9.32	ESR1 ESR2
2	nuclear receptor activity	GO:0004879	9.26	ESR1 ESR2
3	steroid binding	GO:0005496	9.16	ESR1 ESR2
4	estrogen receptor activity	GO:0030284	8.96	ESR1 ESR2
5	estrogen response element binding	GO:0034056	8.62	ESR1 ESR2

Sources

Sources for Endometriosis of Ovary

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia