Endometriosis of Ovary disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: END011 MIFTS: 43	Endometriosis of Ovary Categories: Reproductive diseases, Endocrine diseases
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Aliases & Classifications for Endometriosis of Ovary

MalaCards integrated aliases for Endometriosis of Ovary:

Name: Endometriosis of Ovary ¹² ¹⁵ ⁷³

Ovarian Endometriosis ¹²

Classifications:

MalaCards categories:
Anatomical: Reproductive diseases Endocrine diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the genitourinary system

Noninflammatory disorders of female genital tract

Endometriosis

Endometriosis of ovary

External Ids:

Disease Ontology ¹² DOID:11432

ICD10 ³³ N80.1

ICD9CM ³⁵ 617.1

NCIt ⁵⁰ C27628

SNOMED-CT ⁶⁸ 198250000 266589005 31007005

UMLS ⁷³ C0156344

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Summaries for Endometriosis of Ovary

MalaCards based summary : Endometriosis of Ovary, also known as ovarian endometriosis, is related to adenomyosis and vaginitis. An important gene associated with Endometriosis of Ovary is LINC00339 (Long Intergenic Non-Protein Coding RNA 339), and among its related pathways/superpathways are Gastric cancer and Nuclear Receptor transcription pathway. The drugs Anastrozole and Goserelin have been mentioned in the context of this disorder. Affiliated tissues include ovary, endothelial and uterus, and related phenotypes are endocrine/exocrine gland and muscle

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Related Diseases for Endometriosis of Ovary

Diseases related to Endometriosis of Ovary via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 125)

#	Related Disease	Score	Top Affiliating Genes
1	adenomyosis	30.5	ESR1 PGR
2	vaginitis	30.5	ESR1 ESR2
3	endometrial adenocarcinoma	30.2	ESR1 ESR2 PGR
4	endometriosis	30.1	CYP19A1 ESR1 ESR2 HOXA10 PGR
5	infertility	30.0	CYP19A1 ESR2 PGR
6	endometrial stromal sarcoma	29.9	CYP19A1 ESR1 PGR
7	leiomyoma	29.7	CYP19A1 ESR1 ESR2 PGR
8	postmenopausal atrophic vaginitis	10.8	ESR1 ESR2
9	vulvar syringoma	10.7	ESR1 PGR
10	lung leiomyoma	10.7	ESR1 PGR
11	dental fluorosis	10.7	ESR1 ESR2
12	vestibular gland benign neoplasm	10.7	ESR1 PGR
13	bartholin's gland adenoma	10.7	ESR1 PGR
14	glassy cell carcinoma of the cervix	10.7	ESR1 PGR
15	vulvar benign neoplasm	10.7	ESR1 PGR
16	trigonitis	10.7	ESR1 PGR
17	vulvar leiomyoma	10.7	ESR1 PGR
18	predominantly cortical thymoma	10.7	ESR1 PGR
19	breast medullary carcinoma	10.7	ESR1 PGR
20	breast scirrhous carcinoma	10.7	ESR1 PGR
21	cribriform carcinoma	10.7	ESR1 PGR
22	oncocytic breast carcinoma	10.7	ESR1 PGR
23	endometrial squamous cell carcinoma	10.7	ESR1 PGR
24	gastric signet ring cell adenocarcinoma	10.7	ESR1 PGR
25	endometrial mucinous adenocarcinoma	10.7	ESR1 PGR
26	adenoid basal cell carcinoma	10.7	ESR1 PGR
27	apocrine adenocarcinoma	10.7	ESR1 PGR
28	lobular neoplasia	10.7	ESR1 ESR2
29	bartholin's gland benign neoplasm	10.7	ESR1 PGR
30	deep angioma	10.7	ESR1 PGR
31	synchronous bilateral breast carcinoma	10.7	ESR1 PGR
32	transsexualism	10.7	CYP19A1 ESR2
33	breast adenoid cystic carcinoma	10.7	ESR1 PGR
34	cervical carcinosarcoma	10.6	ESR1 PGR
35	intramuscular hemangioma	10.6	ESR1 PGR
36	glycogen-rich clear cell breast carcinoma	10.6	ESR1 PGR
37	retinitis pigmentosa 47	10.6	ESR1 PGR
38	uterine corpus cancer	10.6	ESR1 PGR
39	estrogen resistance	10.6	ESR1 TRERF1
40	retinitis pigmentosa 20	10.6	ESR1 PGR
41	luminal breast carcinoma	10.6	ESR1 PGR
42	adenosarcoma	10.6	ESR1 PGR
43	cervical clear cell adenocarcinoma	10.6	ESR1 PGR
44	breast benign neoplasm	10.6	ESR1 PGR
45	thoracic benign neoplasm	10.6	ESR1 PGR
46	benign metastasizing leiomyoma	10.6	CYP19A1 PGR
47	inflammatory breast carcinoma	10.6	ESR1 PGR
48	mixed cell type cancer	10.5	ESR1 PGR
49	lipid-rich carcinoma	10.5	ESR1 PGR
50	endometrial stromal nodule	10.5	CYP19A1 PGR

Comorbidity relations with Endometriosis of Ovary via Phenotypic Disease Network (PDN):

Endometriosis of Uterus	Fallopian Tube Endometriosis
Myofibroma

Graphical network of the top 20 diseases related to Endometriosis of Ovary:

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Symptoms & Phenotypes for Endometriosis of Ovary

MGI Mouse Phenotypes related to Endometriosis of Ovary:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland	MP:0005379	9.86	HOXA10 PGR AMH ARID1A CYP19A1 ESR1
2	muscle	MP:0005369	9.63	PGR ARID1A CYP19A1 ESR1 ESR2 HNF1B
3	neoplasm	MP:0002006	9.35	PGR AMH ARID1A ESR1 ESR2
4	reproductive system	MP:0005389	9.17	HOXA10 PGR AMH ARID1A CYP19A1 ESR1

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Drugs & Therapeutics for Endometriosis of Ovary

Drugs for Endometriosis of Ovary (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Anastrozole

Approved, Investigational

Phase 4

120511-73-1

2187

Synonyms:

.alpha.,alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

1,3-benzenediacetonitrile, a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)

120511-73-1

2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)

2,2'-(5-(1H-1,2,4-Triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)

2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)

2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)

2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile

a,a,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

AC1L1D49

AC-4234

alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

alpha,alpha,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

anastrazole

Anastrazole

Anastrole

Anastrozol

anastrozole

Anastrozole (JAN/USAN/INN)

Anastrozole [USAN:INN:BAN]

Arimidex

Arimidex (TN)

Arimidex (Zeneca)

Arimidex, Anastrozole

Asiolex

Astra brand of anastrozole

Astra brand OF anastrozole

AstraZeneca brand of anastrozole

AstraZeneca brand OF anastrozole

C08159

C090450

C17H19N5

CHEBI:2704

CHEMBL1399

CID2187

CPD000466301

D00960

DB01217

HMS2052M11

HMS2089N10

HSDB 7462

I06-0021

ICI D1033

ICI-D 1033

ICI-D1033

LS-29563

MLS000759396

MLS001424217

MolPort-005-933-078

NCGC00164619-01

NSC719344

S1188_Selleck

SAM001246525

SBB066057

SMR000466301

UNII-2Z07MYW1AZ

ZD 1033

ZD1033

ZD-1033

Zeneca brand of anastrozole

Zeneca brand OF anastrozole

Zeneca ZD 1033

ZINC00000941

α,α,alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile

Goserelin

Approved

Phase 4

65807-02-5

47725 5311128

Synonyms:

(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

AC1NSK1T

Acetate, goserelin

CID5311128

goserelin

Goserelin acetate

HMS2089D16

HS-2015

ICI 118

ICI-118630

ICI-118630Zoladex

MolPort-006-823-831

ZD-9393

Zoladex

Antineoplastic Agents, Hormonal

Phase 4,Phase 2

Aromatase Inhibitors

Phase 4

Estrogen Antagonists

Phase 4

Estrogens

Phase 4

Hormone Antagonists

Phase 4

Hormones

Phase 4

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4

Steroid Synthesis Inhibitors

Phase 4

Medroxyprogesterone acetate

Approved, Investigational

Phase 2

71-58-9

Synonyms:

(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione

17-Acetoxy-6alpha-methylprogesterone

17-Acetoxy-6α-methylprogesterone

17alpha-Hydroxy-6alpha-methylprogesterone acetate

17α-hydroxy-6α-methylprogesterone acetate

6alpha-Methyl-17-acetoxy progesterone

6-alpha-Methyl-17-alpha-acetoxyprogesterone

6alpha-Methyl-17alpha-hydroxyprogesterone acetate

6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate

6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate

6α-Methyl-17-acetoxy progesterone

6α-Methyl-17α-hydroxyprogesterone acetate

Medroxyacetate progesterone

Medroxyprogesterone 17-acetate

Medroxyprogesterone acetate

Methylacetoxyprogesterone

Metigestrona

MPA

Contraceptive Agents

Phase 2

Contraceptive Agents, Male

Phase 2

Medroxyprogesterone

Phase 2

520-85-4

10631

Synonyms:

(6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione

(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

17 alpha Hydroxy 6 alpha methylprogesterone

17 alpha Hydroxy 6 alpha Methylprogesterone

17 alpha-Hydroxy-6 alpha-methylprogesterone

17 alpha-Hydroxy-6 alpha-Methylprogesterone

17.alpha.-Hydroxy-6.alpha.-methylprogesterone

17a-Hydroxy-6a-methylprogesterone

17alpha-Hydroxy-6alpha-methyl-4-pregnene-3,20-dione

17alpha-Hydroxy-6alpha-methylprogesterone

17-Hydroxy-6.alpha.-methylprogesterone

17-Hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione

17-Hydroxy-6alpha-methylprogesterone

17-Hydroxy-6a-methyl-pregn-4-ene-3,20-dione

17-Hydroxy-6a-methylprogesterone

17-Hydroxy-6α-methyl-pregn-4-ene-3,20-dione

17-Hydroxy-6α-methylprogesterone

17α-hydroxy-6α-methylprogesterone

4-08-00-02211 (Beilstein Handbook Reference)

46411_FLUKA

46411_RIEDEL

520-85-4

6.alpha.-Methyl-17.alpha.-hydroxyprogesterone

6alpha-Methyl-17alpha-hydroxyprogesterone

6-alpha-Methyl-17-alpha-hydroxyprogesterone

6alpha-Methyl-4-pregnen-17alpha-ol-3,20-dione

6alpha-Methyl-5-pregnen-17alpha-ol-3,20-dione

6a-Methyl-17a-hydroxyprogesterone

6a-Methyl-4-pregnen-17a-ol-3,20-dione

6-Dihydromegestrol

6α-methyl-17α-hydroxyprogesterone

6α-methyl-4-pregnen-17α-ol-3,20-dione

AC-14528

AC1L1VM7

Adgyn medro

Adgyn Medro

Aragest

Aragest 5

Asconale

BRN 2510965

C07119

CBP-1011

CHEBI:6715

CHEMBL1390

CID10631

Clinofem

Clinovir

Colirest

CPD000058769

Cycrin

D008525

D08166

DB00603

Depo-Clinovir

Depo-Prodasone

Depo-Progestin

Depo-Promone

depo-Provera

depo-Subq provera 104

Depot-Medroxyprogesterone acetate

DMPA

EINECS 208-298-6

Farlutal

Farlutal inyectable

Farlutal inyectable (TN)

Farlutin

Gestapuran

g-Farlutal

G-Farlutal

Hematrol

HMS2052A13

HSDB 3114

Hydroxymethylprogesterone

Hysron

Indivina

LMST02030176

LS-118713

Lunelle

Lutopolar

Lutoral

M6013_SIGMA

MAP

Med-Pro

Medroprogesterone Acetate

Medrossiprogesterone

Medrossiprogesterone [Dcit]

Medrossiprogesterone [DCIT]

Medroxiprogesterona

Medroxiprogesterona [INN-Spanish]

Medroxiprogesteronum

Medroxyprogesteron

Medroxyprogesteron acetate

medroxyprogesterone

Medroxyprogesterone (INN)

Medroxyprogesterone [INN:BAN]

Medroxyprogesterone acetate

Medroxyprogesterone strakan brand

Medroxyprogesterone Strakan Brand

Medroxyprogesteronum

Medroxyprogesteronum [INN-Latin]

Meprate

Methylhydroxyprogesterone

Metigestrona

MLS000069571

MLS001076098

MolPort-005-934-866

MPA Gyn 5

Nadigest

NCGC00023064-04

Nidaxin

Novo-Medrone

NSC 27408

NSC27408

Oragest

Perlutex

Perlutex Leo

Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)- (9CI)

Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6-alpha)- (9CI)

Prodasone

Progestalfa

Progevera

Provera

Proverone

Ralovera

Repromap

Repromix

SAM001246906

Sirprogen

SMR000058769

Sodelut G

ST082267

Strakan brand OF medroxyprogesterone

Strakan Brand of Medroxyprogesterone

U 8840

UNII-HSU1C9YRES

Veramix

ZINC05763835

Edetic Acid

Approved, Vet_approved

Not Applicable

60-00-4, 62-33-9

6049

Synonyms:

(ethylenedinitrilo)Tetraacetate, ion(4-)

(ethylenedinitrilo)tetraacetic acid, ion(4−)

(ethylenedinitrilo)Tetraacetic acid, ion(4-)

{[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetate

{[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid

{[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetIC ACID

2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate

2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid

Acid, edetic

Acid, ethylenediaminetetraacetic

Acid, ethylenedinitrilotetraacetic

acide edetique

Acide edetique

Acide ethylenediaminetetracetique

acido Edetico

Acido edetico

Acidum edeticum

CaEDTA

Calcitetracemate, disodium

Calcium disodium edetate

Calcium disodium versenate

Calcium tetacine

Chelaton 3

Chromium edta

Copper edta

Coprin

Dicobalt edta

Dinitrilotetraacetate, disodium ethylene

Dinitrilotetraacetate, ethylene

Disodium calcitetracemate

Disodium edta

Disodium ethylene dinitrilotetraacetate

Disodium versenate, calcium

Distannous edta

Edathamil

Edetate

Edetate calcium

Edetate calcium disodium

Edetate disodium calcium

Edetate, calcium disodium

Edetates

Edetic acid, calcium salt

Edetic acid, calcium, sodium salt

Edetic acid, chromium salt

Edetic acid, dipotassium salt

Edetic acid, disodium salt

Edetic acid, disodium salt, dihydrate

Edetic acid, disodium, magnesium salt

Edetic acid, disodium, monopotassium salt

Edetic acid, magnesium salt

Edetic acid, monopotassium salt

Edetic acid, monosodium salt

Edetic acid, potassium salt

Edetic acid, sodium salt

EDT

EDTA

EDTA, chromium

EDTA, copper

EDTA, dicobalt

EDTA, disodium

EDTA, distannous

EDTA, gallium

EDTA, ion(4-)

EDTA, magnesium disodium

EDTA, potassium

EDTA, stannous

Ethylene dinitrilotetraacetate

Ethylene dinitrilotetraacetate, disodium

Ethylenediaminetetraacetate

Ethylenediaminetetraacetic acid

Ethylenedinitrilotetraacetic acid

Gallium edta

H4EDta

Magnesium disodium edta

N,N'-1,2-ethane diylbis-(N-(carboxymethyl)glycine)

N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine)

N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine)

Potassium edta

Stannous edta

Tetacine, calcium

Tetracemate

Versenate

Versenate, calcium disodium

Versene

Pentetic acid

Approved

Not Applicable

67-43-6

Anesthetics

Not Applicable

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis	Completed	NCT00286351	Phase 4	Combined treatment with Arimidex and Zoladex before IVF
2	PGL5001 Proof of Concept Study in Inflammatory Endometriosis	Completed	NCT01630252	Phase 2	PGL5001;Placebo;PGL5001;Placebo;PGL5001
3	Safety, Tolerability and Efficacy of Vaginal Suppositories for Treatment of the Endometriosis	Not yet recruiting	NCT03481842	Phase 1, Phase 2	BIBW2992;Axitinib
4	Somatic Stem Cells in Endometriosis	Unknown status	NCT01412138
5	Assessment of Telomerase Activity in Endometrial Tissue and Serum in Endometriosis Patients	Completed	NCT02984774	Not Applicable
6	Artificial Reproductive Techniques (ART) and Progression of Endometriosis Symptoms	Completed	NCT02762461
7	Perinatal Consequences of Endometriosis	Recruiting	NCT02498691	Not Applicable
8	Ovarian Function After Use of Various Hemostatic Techniques During Treatment for Endometrioma	Not yet recruiting	NCT03430609	Not Applicable

Search NIH Clinical Center for Endometriosis of Ovary

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Genetic Tests for Endometriosis of Ovary

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Anatomical Context for Endometriosis of Ovary

MalaCards organs/tissues related to Endometriosis of Ovary:

⁴¹

Ovary, Endothelial, Uterus, Cervix, Cortex, Liver, Smooth Muscle

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Publications for Endometriosis of Ovary

Articles related to Endometriosis of Ovary:

(show top 50) (show all 184)

#	Title	Authors	Year
1	Significance of Ovarian Endometriosis on the Prognosis of Ovarian Clear Cell Carcinoma. ( 28930811 )	Park J.Y....Nam J.H.	2017
2	Use of medroxyprogesterone acetate in women with ovarian endometriosis undergoing controlled ovarian hyperstimulation for in vitro fertilization. ( 28931865 )	Guo H....Kuang Y.	2017
3	Silencing of SRA1 Regulates ER Expression and Attenuates the Growth of Stromal Cells in Ovarian Endometriosis. ( 27694140 )	Lin K....Lin J.	2017
4	Transverse Relaxation Rate of Cyst Fluid Can Predict Malignant Transformation of Ovarian Endometriosis. ( 27646154 )	Yoshimoto C....Kobayashi H.	2016
5	EP27.12: EndometriomaA -A the tip of a pelvic disease: TVS findings associated with an ovarian endometriosis. ( 27647664 )	Exacoustos C....Zupi E.	2016
6	The co-expression of GPER and Gankyrin in ovarian endometriosis and its correlation with the rASRM stages. ( 26193952 )	Zhang C....Zhang Y.	2016
7	Increased Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Patients With Ovarian Endometriosis. ( 26342048 )	Jiang J.F....Sun A.J.	2016
8	Persistent Mullerian Duct Syndrome with Ovarian Endometriosis-A Rare Case Report. ( 27042476 )	Nerune S.M....Mehrotra N.M.	2016
9	Bilateral Ovarian Clear Cell Carcinoma Arising in 17 Year Longstanding History of Bilateral Ovarian Endometriosis. ( 28974971 )	Win T.T....Ismail M.	2016
10	Autophagy is upregulated in ovarian endometriosis: a possible interplay with p53 and heme oxygenase-1. ( 25772769 )	Allavena G....Maellaro E.	2015
11	Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2I+ biosynthesis and action in ovarian endometriosis tissue and in model cell lines. ( 25446850 )	Sinreih M....RiA3ner T.L.	2015
12	MiR-191 inhibits TNF-I+ induced apoptosis of ovarian endometriosis and endometrioid carcinoma cells by targeting DAPK1. ( 26191186 )	Tian X....Wang P.	2015
13	Phospholipase A2 group IIA is elevated in endometriomas but not in peritoneal fluid and serum of ovarian endometriosis patients. ( 25366587 )	Kocbek V....RiA3ner T.L.	2014
14	RUNX3 is inactivated by promoter hypermethylation in malignant transformation of ovarian endometriosis. ( 25333219 )	Guo C....Chen P.	2014
15	Genetic variation of the E-cadherin gene is associated with primary infertility in patients with ovarian endometriosis. ( 25150394 )	Kang S....Zhao X.W.	2014
16	Genome-wide profiling of long noncoding ribonucleic acid expression patterns in ovarian endometriosis by microarray. ( 24502888 )	Sun P.R....Lang J.H.	2014
17	Increased expression of the pluripotency markers sex-determining region Y-box 2 and Nanog homeobox in ovarian endometriosis. ( 24884521 )	Song Y....Yang S.	2014
18	Tubal origin of ovarian endometriosis. ( 24390223 )	Yuan Z....Zheng W.	2014
19	Surgically treated ovarian endometriosis association with BRCA1 and BRCA2 mutations. ( 24472143 )	Aviel-Ronen S....Cohen Y.	2014
20	MicroRNA23a and microRNA23b deregulation derepresses SF-1 and upregulates estrogen signaling in ovarian endometriosis. ( 23450049 )	Shen L....Liu Y.	2013
21	High-resolution array-comparative genomic hybridization profiling reveals 20q13.33 alterations associated with ovarian endometriosis. ( 23656391 )	Yang W....Li R.	2013
22	MicroRNAs expression profiling of eutopic proliferative endometrium in women with ovarian endometriosis. ( 23945042 )	Laudanski P....Niklinski J.	2013
23	Elevated glycodelin-A concentrations in serum and peritoneal fluid of women with ovarian endometriosis. ( 23461865 )	Kocbek V....Bersinger N.A.	2013
24	Long term survival of ovarian endometriosis associated clear cell and endometrioid ovarian cancers. ( 23314280 )	Noli S....Parazzini F.	2013
25	Disturbed balance between phase I and II metabolizing enzymes in ovarian endometriosis: a source of excessive hydroxy-estrogens and ROS? ( 23277161 )	Hevir N....LaniA!nik RiA3ner T.	2013
26	Loss of ARID1A/BAF250a expression in ovarian endometriosis and clear cell carcinoma. ( 22977660 )	Xiao W....Xin W.	2012
27	CDC42-positive macrophages may prevent malignant transformation of ovarian endometriosis. ( 21944080 )	Canet B....Prat J.	2012
28	The G-protein-coupled estrogen receptor (GPER) is expressed in normal human ovaries and is upregulated in ovarian endometriosis and pelvic inflammatory disease involving the ovary. ( 22573494 )	Heublein S....Jeschke U.	2012
29	Dienogest increases the progesterone receptor isoform B/A ratio in patients with ovarian endometriosis. ( 23113924 )	Hayashi A....Ohmichi M.	2012
30	The ferroimmunomodulatory role of ectopic endometriotic stromal cells in ovarian endometriosis. ( 22633261 )	Kobayashi H....Toyokuni S.	2012
31	Involvement of pelvic inflammation-related mismatch repair abnormalities and microsatellite instability in the malignant transformation of ovarian endometriosis. ( 22626277 )	Fuseya C....Shiozawa T.	2012
32	Epigenetic inactivation of hMLH1 in the malignant transformation of ovarian endometriosis. ( 21556900 )	Ren F....Ren F.	2012
33	Genetic polymorphisms of DNMT3L involved in hypermethylation of chromosomal ends are associated with greater risk of developing ovarian endometriosis. ( 22401780 )	Borghese B....Chapron C.	2012
34	Fertility preservation in women with ovarian endometriosis. ( 22201982 )	Donnez J....Donnez O.	2012
35	Borderline clear cell adenofibroma of the ovary associated with ovarian endometriosis: a case report. ( 22611972 )	Vasilakaki T....Manoloudaki K.	2012
36	Discovery of phosphatidylcholines and sphingomyelins as biomarkers for ovarian endometriosis. ( 22859507 )	Vouk K....Adamski J.	2012
37	Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis. ( 21232532 )	Hevir N....RiA3ner T.L.	2011
38	Follicular loss in endoscopic surgery for ovarian endometriosis: quantitative and qualitative observations. ( 21703608 )	Romualdi D....Guido M.	2011
39	Possible involvement of loss of heterozygosity in malignant transformation of ovarian endometriosis. ( 21130491 )	Xu B....Kitawaki J.	2011
40	Primary squamous cell carcinoma associated with ovarian endometriosis: a case report and literature review. ( 21301917 )	Yamakawa Y....Kato K.	2011
41	Frequency of ovarian endometriosis in epithelial ovarian cancer patients. ( 22268283 )	Dzatic-Smiljkovic O....Vugdelic J.	2011
42	Involvement of estrogen receptor-related receptors in human ovarian endometriosis. ( 21561608 )	Cavallini A....Loverro G.	2011
43	Expression patterns of the steroid receptor coactivator family in human ovarian endometriosis. ( 21518137 )	Kumagami A....Sato A.	2011
44	Two-dimensional gel electrophoresis in peritoneal fluid samples identifies differential protein regulation in patients suffering from peritoneal or ovarian endometriosis. ( 21497343 )	WAPlfler M.M....Henkel C.	2011
45	Novel estrogen-related genes and potential biomarkers of ovarian endometriosis identified by differential expression analysis. ( 21397694 )	Vouk K....RiA3ner T.L.	2011
46	Identification of cells with colony-forming activity, self-renewal capacity, and multipotency in ovarian endometriosis. ( 21641404 )	Chan R.W....Yeung W.S.	2011
47	Immunohistochemical detection of steroid receptor cofactors in ovarian endometriosis: involvement of down-regulated SRC-1 expression in the limited growth activity of the endometriotic epithelium. ( 20155281 )	Suzuki A....Shiozawa T.	2010
48	Steroidogenic factor-1 expression in ovarian endometriosis. ( 19875956 )	NoAl J.C....Chapron C.	2010
49	Immunohistochemical localization of inhibin and activin subunits, activin receptors and Smads in ovarian endometriosis. ( 19956897 )	Mabuchi Y....Umesaki N.	2010
50	Immunohistochemical expression of matrix metalloproteinases, their tissue inhibitors, and cathepsin-D in ovarian endometriosis: correlation with severity of disease. ( 20385381 )	Protopapas A....Antsaklis A.	2010

Sources

Genes for Endometriosis of Ovary

Genes related to Endometriosis of Ovary (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	LINC00339	Long Intergenic Non-Protein Coding RNA 339	RNA Gene	15.37	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	ESR2	Estrogen Receptor 2	Protein Coding	15.31	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	TRERF1	Transcriptional Regulating Factor 1	Protein Coding	15.19	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	HNF1B	HNF1 Homeobox B	Protein Coding	15.18	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	ESR1	Estrogen Receptor 1	Protein Coding	15.18	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	PGR	Progesterone Receptor	Protein Coding	15.09	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	FMO3	Flavin Containing Monooxygenase 3	Protein Coding	15.08	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	CYP19A1	Cytochrome P450 Family 19 Subfamily A Member 1	Protein Coding	15.02	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	ARID1A	AT-Rich Interaction Domain 1A	Protein Coding	14.99	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	TRIM36	Tripartite Motif Containing 36	Protein Coding	14.98	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
11	HOXA10	Homeobox A10	Protein Coding	14.9	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
12	AMH	Anti-Mullerian Hormone	Protein Coding	14.87	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
13	HSD17B2	Hydroxysteroid 17-Beta Dehydrogenase 2	Protein Coding	14.86	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

Sources

Variations for Endometriosis of Ovary

Sources

Expression for Endometriosis of Ovary

Search GEO for disease gene expression data for Endometriosis of Ovary.

Sources

Pathways for Endometriosis of Ovary

Pathways related to Endometriosis of Ovary according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Gastric cancer ³⁷ Show member pathways Breast cancer ³⁷ Hepatocellular carcinoma ³⁷	12.29	ARID1A ESR1 ESR2 PGR
2	Nuclear Receptor transcription pathway ⁶⁶ Show member pathways Nuclear Receptors ¹	11.29	ESR1 ESR2 PGR
3	Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2 ²²	10.85	ESR1 ESR2
4	Plasma membrane estrogen receptor signaling ¹	10.78	ESR1 ESR2
5	Ovarian Infertility Genes ¹	10.64	CYP19A1 ESR2 PGR
6	MNAR-PELP1 and Estrogen Receptor Interaction ⁶⁴	10.62	ESR1 ESR2
7	Aromatase Inhibitor Pathway (Breast Cell), Pharmacodynamics ⁶¹	9.4	CYP19A1 ESR1 ESR2

Sources

GO Terms for Endometriosis of Ovary

Cellular components related to Endometriosis of Ovary according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	transcription factor complex	GO:0005667	8.8	HNF1B HOXA10 TRERF1

Biological processes related to Endometriosis of Ovary according to GeneCards Suite gene sharing:

(show all 12)

#	Name	GO ID	Score	Top Affiliating Genes
1	transcription, DNA-templated	GO:0006351	9.98	ARID1A ESR1 ESR2 HNF1B HOXA10 PGR
2	positive regulation of transcription, DNA-templated	GO:0045893	9.72	ARID1A ESR1 ESR2 HNF1B TRERF1
3	transcription initiation from RNA polymerase II promoter	GO:0006367	9.63	ESR1 ESR2 PGR
4	mammary gland development	GO:0030879	9.51	CYP19A1 PGR
5	regulation of Wnt signaling pathway	GO:0030111	9.48	ESR1 HNF1B
6	steroid biosynthetic process	GO:0006694	9.43	CYP19A1 HSD17B2 TRERF1
7	androgen metabolic process	GO:0008209	9.4	CYP19A1 ESR1
8	estrogen biosynthetic process	GO:0006703	9.37	CYP19A1 HSD17B2
9	steroid hormone mediated signaling pathway	GO:0043401	9.33	ESR1 ESR2 PGR
10	intracellular estrogen receptor signaling pathway	GO:0030520	9.13	ARID1A ESR1 ESR2
11	uterus development	GO:0060065	8.8	CYP19A1 ESR1 HOXA10
12	regulation of transcription, DNA-templated	GO:0006355	10.04	ARID1A ESR1 ESR2 HNF1B HOXA10 PGR

Molecular functions related to Endometriosis of Ovary according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	9.95	ARID1A ESR1 ESR2 HNF1B HOXA10 PGR
2	sequence-specific DNA binding	GO:0043565	9.83	ESR1 ESR2 HNF1B HOXA10 PGR
3	steroid hormone receptor activity	GO:0003707	9.54	ESR1 ESR2 PGR
4	nuclear receptor activity	GO:0004879	9.33	ESR1 ESR2 PGR
5	estrogen receptor activity	GO:0030284	9.32	ESR1 ESR2
6	estrogen response element binding	GO:0034056	9.26	ESR1 ESR2
7	steroid binding	GO:0005496	9.13	ESR1 ESR2 PGR
8	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding	GO:0038052	8.62	ESR1 ESR2
9	DNA binding	GO:0003677	10	ARID1A ESR1 ESR2 HNF1B HOXA10 PGR

Sources

Sources for Endometriosis of Ovary

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia