MCID: END011
MIFTS: 35

Endometriosis of Ovary

Categories: Endocrine diseases, Reproductive diseases

Aliases & Classifications for Endometriosis of Ovary

MalaCards integrated aliases for Endometriosis of Ovary:

Name: Endometriosis of Ovary 12 15 72 33
Ovarian Endometriosis 12 17

Classifications:



External Ids:

Disease Ontology 12 DOID:11432
ICD9CM 35 617.1
NCIt 50 C27628
SNOMED-CT 68 31007005
ICD10 33 N80.1
UMLS 72 C0156344

Summaries for Endometriosis of Ovary

Disease Ontology : 12 A female reproductive system disease characterized by the growth of endometrial tissue that is located in the ovary.

MalaCards based summary : Endometriosis of Ovary, also known as ovarian endometriosis, is related to endometriosis and ovarian cyst. An important gene associated with Endometriosis of Ovary is MIR141 (MicroRNA 141), and among its related pathways/superpathways is Mesodermal Commitment Pathway. The drugs Goserelin and Anastrozole have been mentioned in the context of this disorder. Affiliated tissues include ovary, uterus and endothelial.

Wikipedia : 75 Endometrioma is the presence of endometrial tissue in and sometimes on the ovary. It is the most common... more...

Related Diseases for Endometriosis of Ovary

Diseases related to Endometriosis of Ovary via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Related Disease Score Top Affiliating Genes
1 endometriosis 11.1
2 ovarian cyst 10.5
3 extrapelvic endometriosis 10.4
4 ovarian cancer 10.4
5 infertility 10.4
6 adenomyosis 10.3
7 leiomyoma 10.3
8 ovarian clear cell carcinoma 10.2
9 ovarian epithelial cancer 10.2
10 leiomyoma, uterine 10.2
11 endometrial cancer 10.2
12 enhanced s-cone syndrome 10.1
13 myoma 10.1
14 adenocarcinoma 10.1
15 serous cystadenocarcinoma 10.1
16 mature teratoma 10.1
17 squamous cell carcinoma 10.1
18 cystic teratoma 10.1
19 teratoma 10.1
20 endometrioid ovary carcinoma 10.1
21 hydatidiform mole, recurrent, 1 10.0
22 progesterone resistance 10.0
23 premature ovarian failure 1 10.0
24 body mass index quantitative trait locus 1 10.0
25 ectopic pregnancy 10.0
26 pelvic inflammatory disease 10.0
27 ovarian disease 10.0
28 sarcoma 10.0
29 ulceration of vulva 10.0
30 amenorrhea 10.0
31 acromegaly 10.0
32 cystadenoma 10.0
33 dermoid cyst 10.0
34 adenofibroma 10.0
35 cystadenocarcinoma 10.0
36 gestational trophoblastic neoplasm 10.0
37 arthropathy 10.0
38 endometrial stromal sarcoma 10.0
39 spindle cell sarcoma 10.0
40 clear cell adenocarcinoma 10.0
41 leiomyomatosis 10.0
42 diffuse peritoneal leiomyomatosis 10.0
43 intravenous leiomyomatosis 10.0
44 ovarian serous cystadenocarcinoma 10.0
45 adenoma 10.0
46 in situ carcinoma 10.0
47 cervix uteri carcinoma in situ 10.0
48 cervical intraepithelial neoplasia 10.0
49 overgrowth syndrome 10.0
50 neurofibromatosis, type ii 9.8

Comorbidity relations with Endometriosis of Ovary via Phenotypic Disease Network (PDN):


Fallopian Tube Endometriosis Myofibroma

Graphical network of the top 20 diseases related to Endometriosis of Ovary:



Diseases related to Endometriosis of Ovary

Symptoms & Phenotypes for Endometriosis of Ovary

Drugs & Therapeutics for Endometriosis of Ovary

Drugs for Endometriosis of Ovary (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Goserelin Approved Phase 4 65807-02-5, 1233494-97-7 47725 5311128
2
Anastrozole Approved, Investigational Phase 4 120511-73-1 2187
3 Estrogens Phase 4
4 Steroid Synthesis Inhibitors Phase 4
5 Antineoplastic Agents, Hormonal Phase 4
6 Estrogen Receptor Antagonists Phase 4
7 Aromatase Inhibitors Phase 4
8 Estrogen Antagonists Phase 4
9
Medroxyprogesterone acetate Approved, Investigational Phase 2 71-58-9
10 Contraceptive Agents, Male Phase 2
11 Contraceptive Agents Phase 2
12
Medroxyprogesterone Phase 2 520-85-4 10631
13 Hormones
14 Hormone Antagonists
15 Hormones, Hormone Substitutes, and Hormone Antagonists
16 Hemostatics
17 Coagulants
18 Follicle Stimulating Hormone

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis Completed NCT00286351 Phase 4 Combined treatment with Arimidex and Zoladex before IVF
2 A Phase IIa Efficacy and Safety Study of PGL5001 Versus Placebo Administered for up to 5 Months With Concomitant Administration of Depot Medroxyprogesterone Acetate for the Treatment of Peritoneal and/or Ovarian Endometriosis With an Inflammatory Component. Completed NCT01630252 Phase 2 PGL5001;Placebo;PGL5001;Placebo;PGL5001
3 "Identification, Characterization and Isolation of Somatic Stem Cells in Human Endometrium of Women With Endometriosis" Unknown status NCT01412138
4 Impact on Ovarian Reserve According to the Type of Ovarian Endometrioma Excision: Laser Versus Conventional Cystectomy Completed NCT03826355
5 Optimum Menstrual Cycle Time for Endometrioma Excision Recruiting NCT03484546
6 Perinatal Consequences of Endometriosis: Multicenter Prospective Comparative Study Active, not recruiting NCT02498691
7 Study of the Relationship Between Oxidative Stress Gene Polymorphism and Individual Variation of Ovarian Reserve Function in Patients With Ovarian Endometrioma Not yet recruiting NCT03682341
8 Ovarian Function After Use of Various Hemostatic Techniques During Treatment for Endometrioma: A Randomized Control Trial Not yet recruiting NCT03430609

Search NIH Clinical Center for Endometriosis of Ovary

Genetic Tests for Endometriosis of Ovary

Anatomical Context for Endometriosis of Ovary

MalaCards organs/tissues related to Endometriosis of Ovary:

41
Ovary, Uterus, Endothelial, Colon, T Cells, Liver, Breast

The Foundational Model of Anatomy Ontology organs/tissues related to Endometriosis of Ovary:

19
Ovary

Publications for Endometriosis of Ovary

Articles related to Endometriosis of Ovary:

(show top 50) (show all 740)
# Title Authors PMID Year
1
MRI features and differential diagnoses of congenital vaginal atresia. 38
30982355 2019
2
Endometriosis of the duplex appendix: A case report and review of the literature. 38
31423443 2019
3
Recurrence rate after "one step" CO2 fiber laser vaporization versus cystectomy for ovarian endometrioma: a 3-year follow-up study. 38
31377455 2019
4
Comprehensive immune complexome analysis detects disease-specific immune complex antigens in seminal plasma and follicular fluids derived from infertile men and women. 38
31158356 2019
5
Roles of cell migration and invasion mediated by Twist in endometriosis. 38
31250947 2019
6
Factors associated with ovarian endometriosis malignancy and its recurrence in Chinese women. 38
31307261 2019
7
A randomized controlled trial of a new technique for laparoscopic management of ovarian endometriosis preventing recurrence and keeping ovarian reserve. 38
31325962 2019
8
Single-cell RNA sequencing of oocytes from ovarian endometriosis patients reveals a differential transcriptomic profile associated with lower quality. 38
31211846 2019
9
Elevated urine histone 4 levels in women with ovarian endometriosis revealed by discovery and parallel reaction monitoring proteomics. 38
31146047 2019
10
Reproductive, obstetric, and perinatal outcomes of women with adenomyosis and endometriosis: a systematic review and meta-analysis. 38
31318420 2019
11
Alterations in β-catenin, microsatellite instability, and HNF-1β levels are independently associated with ovarian endometriosis-associated tumorigenesis. 38
31022415 2019
12
Pregnancy after Endometriosis: Maternal and Neonatal Outcomes according to the Location of the Disease. 38
31238367 2019
13
Circular RNA expression profiles and bioinformatics analysis in ovarian endometriosis. 38
31144476 2019
14
Inhibition of KIF20A by BKS0349 reduces endometriotic lesions in a xenograft mouse model. 38
31365745 2019
15
Is dienogest the best medical treatment for ovarian endometriomas? Results of a multicentric case control study. 38
31311360 2019
16
Preoperative serum anti-Müllerian hormone level is a potential predictor of ovarian endometrioma severity and postoperative fertility. 38
31255930 2019
17
Leyomiomatosis peritonealis disseminata associated with ovarian endometriosis in a patient submitted to hysteroscopic myomectomy. 38
31030890 2019
18
Aberrant methylation of the IL-12B promotor region contributes to the risk of developing ovarian endometriosis. 38
30865360 2019
19
Downregulated circular RNA hsa_circ_0067301 regulates epithelial-mesenchymal transition in endometriosis via the miR-141/Notch signaling pathway. 38
31023528 2019
20
Right postoperative pleural effusion and pulmonary embolism following laparoscopic gynecological surgery : A rare case report and PRISMA-driven systematic review. 38
31135576 2019
21
Pathogenetic gene changes of eutopic endometrium in patients with ovarian endometriosis. 38
30882467 2019
22
Aberrant expression of CHL1 gene and long non-coding RNA CHL1-AS1, CHL1-AS2 in ovarian endometriosis. 38
30943448 2019
23
Hypomethylation of the GSTM1 promoter is associated with ovarian endometriosis. 38
30989213 2019
24
Mitochondria and oxidative stress in ovarian endometriosis. 38
30926565 2019
25
Genome-wide analysis of DNA methylation in endometriosis using Illumina Human Methylation 450 K BeadChips. 38
30740831 2019
26
MicroRNA-488 inhibits endometrial glandular epithelial cell proliferation, migration, and invasion in endometriosis mice via Wnt by inhibiting FZD7. 38
30729701 2019
27
Nodal induces apoptosis and inhibits proliferation in ovarian endometriosis-clear cell carcinoma lesions. 38
30943930 2019
28
Vibrational characterization of granulosa cells from patients affected by unilateral ovarian endometriosis: New insights from infrared and Raman microspectroscopy. 38
30639914 2019
29
A research on the protein expression of p53, p16, and MDM2 in endometriosis. 38
30946310 2019
30
Downregulation of lncrna uca1 as a diagnostic and prognostic biomarker for ovarian endometriosis. 38
30994830 2019
31
Treatment of ovarian endometrial cysts in the context of recurrence and fertility. 38
30659784 2019
32
Relationship between the methylation levels of Twist gene and pathogenesis of endometriosis. 38
30942161 2019
33
Genomic evidence of Y chromosome microchimerism in the endometrium during endometriosis and in cases of infertility. 38
30760267 2019
34
CYFRA 21-1 and Placental Growth Factor as Screening Markers for Endometriosis. 38
30737365 2019
35
Metabolomics analysis of follicular fluid in women with ovarian endometriosis undergoing in vitro fertilization. 38
29806498 2019
36
IFITM1 is a Novel, Highly Sensitive Marker for Endometriotic Stromal Cells in Ovarian and Extragenital Endometriosis. 38
30791812 2019
37
Newly Categorized Seromucinous Tumor of the Ovary: Magnetic Resonance Imaging Findings. 38
30052618 2019
38
LPAR2 and LPAR4 are the Main Receptors Responsible for LPA Actions in Ovarian Endometriotic Cysts. 38
29621954 2019
39
Extra-uterine low grade endometrioid stromal sarcoma arising from ovarian endometriosis: a case report and review of the literature. 38
30723546 2019
40
Mutation analysis of ZP1, ZP2, ZP3 and ZP4 genes in 152 Han Chinese samples with ovarian endometriosis. 38
30611916 2019
41
Similar Characteristics of Endometrial and Endometriotic Epithelial Cells. 38
29402201 2019
42
Impaired Localization of Claudin-11 in Endometriotic Epithelial Cells Compared to Endometrial Cells. 38
30514158 2018
43
Expression Profile Analysis of Circular RNAs in Ovarian Endometriosis by Microarray and Bioinformatics. 38
30566420 2018
44
Ovarian endometriosis and infertility: in vitro fertilization (IVF) or surgery as the first approach? 38
30503109 2018
45
Increased expression of stemness genes REX-1, OCT-4, NANOG, and SOX-2 in women with ovarian endometriosis versus normal endometrium: A case-control study. 38
31417979 2018
46
Concomitant endometriosis in malignant and borderline ovarian tumours. 38
29884083 2018
47
Ovarian carcinomas: at least five different diseases with distinct histological features and molecular genetics. 38
29944973 2018
48
Aberrant expression of genes associated with stemness and cancer in endometria and endometrioma in a subset of women with endometriosis. 38
30020448 2018
49
Analysis of long non-coding RNA expression profiles using RNA sequencing in ovarian endometriosis. 38
29920364 2018
50
Decreased Expression of HOXA10 May Activate the Autophagic Process in Ovarian Endometriosis. 38
29658437 2018

Variations for Endometriosis of Ovary

Expression for Endometriosis of Ovary

Search GEO for disease gene expression data for Endometriosis of Ovary.

Pathways for Endometriosis of Ovary

Pathways related to Endometriosis of Ovary according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.41 TRERF1 MIR141 HNF1B AMH

GO Terms for Endometriosis of Ovary

Sources for Endometriosis of Ovary

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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