MCID: END046
MIFTS: 49

Endometritis

Categories: Reproductive diseases

Aliases & Classifications for Endometritis

MalaCards integrated aliases for Endometritis:

Name: Endometritis 12 55 44 15 17 72

Classifications:



External Ids:

Disease Ontology 12 DOID:1002
MeSH 44 D004716
NCIt 50 C26764
SNOMED-CT 68 78623009
UMLS 72 C0014179

Summaries for Endometritis

Disease Ontology : 12 An endometrial disease that is characterized by inflammation of the endometrium.

MalaCards based summary : Endometritis is related to chlamydia and bacterial vaginosis. An important gene associated with Endometritis is IL1B (Interleukin 1 Beta), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Allograft rejection. The drugs Amoxicillin and Ofloxacin have been mentioned in the context of this disorder. Affiliated tissues include uterus, placenta and colon, and related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 75 Endometritis is inflammation of the inner lining of the uterus (endometrium). Symptoms may include... more...

Related Diseases for Endometritis

Diseases in the Endometritis family:

Acute Endometritis

Diseases related to Endometritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 318)
# Related Disease Score Top Affiliating Genes
1 chlamydia 31.9 TNF IL6 IL1B
2 bacterial vaginosis 31.6 TNF IL6 IL1B
3 peritonitis 31.5 TNF IL6 IL1B
4 chorioamnionitis 31.1 TNF OXT IL6 IL1B
5 vaginitis 31.0 IL6 IL1B ESR1
6 toxic shock syndrome 31.0 TNF IL6 IL1B
7 cytomegalovirus infection 30.9 TNF IL6 IL1B
8 mastitis 30.9 OXT IL6 HP
9 endometriosis 30.9 PGR IL6 IL1B ESR1
10 streptococcal toxic-shock syndrome 30.8 TNF IL6
11 myoma 30.7 PGR OXT ESR1
12 bacterial infectious disease 30.6 TNF IL6 IL1B
13 q fever 30.6 TNF IL6 IL1B
14 leptospirosis 30.6 TNF IL6 IL1B
15 pyelonephritis 30.6 TNF IL6 IL1B
16 appendicitis 30.6 TNF IL6 IL1B
17 uterine anomalies 30.5 PGR OXT IL6 ESR1
18 viral infectious disease 30.4 TNF IL6 IL1B
19 haemophilus influenzae 30.4 TNF IL1B
20 leiomyoma, uterine 30.3 PGR MIRLET7C ESR1
21 meningitis 29.9 TNF IL6 IL1B CXCL1
22 pneumonia 29.5 TNF IL6 IL1B CXCL1
23 endometrial disease 29.1 TNF OXT IL6 IL1B HP ESR1
24 acute gonococcal endometritis 12.7
25 acute endometritis 12.6
26 granulomatous endometritis 12.6
27 non specific chronic endometritis 12.5
28 salpingitis 11.6
29 cervical endometrial stromal sarcoma 11.2
30 exudative glomerulonephritis 10.7 TNF IL1B
31 scorpion envenomation 10.7 TNF IL6
32 recurrent corneal erosion 10.7 IL6 IL1B
33 vaginal discharge 10.7
34 infertility 10.7
35 bagassosis 10.7 IL6 IL1B
36 staphylococcal toxic shock syndrome 10.7 TNF IL1B
37 bartholin's gland adenoma 10.7 PGR ESR1
38 vestibular gland benign neoplasm 10.7 PGR ESR1
39 periodontitis, chronic 10.7 IL6 IL1B
40 angioimmunoblastic lymphadenopathy with dysproteinemia 10.7 TNF IL6
41 lung leiomyoma 10.7 PGR ESR1
42 pelvic inflammatory disease 10.7
43 vulvar syringoma 10.7 PGR ESR1
44 autoimmune myocarditis 10.7 TNF IL6
45 glassy cell carcinoma of the cervix 10.6 PGR ESR1
46 cardiogenic shock 10.6 TNF IL6
47 kashin-beck disease 10.6 TNF IL1B
48 vulvar leiomyoma 10.6 PGR ESR1
49 trigonitis 10.6 PGR ESR1
50 juvenile ankylosing spondylitis 10.6 TNF IL6

Graphical network of the top 20 diseases related to Endometritis:



Diseases related to Endometritis

Symptoms & Phenotypes for Endometritis

MGI Mouse Phenotypes related to Endometritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.11 CHKB ESR1 HLA-DQB1 IL6 OXT PGR
2 homeostasis/metabolism MP:0005376 10.1 CHKB ESR1 GLUD1 HLA-DQB1 HP IL1B
3 cardiovascular system MP:0005385 10.09 ESR1 HLA-DQB1 HP IL1B IL6 OXT
4 hematopoietic system MP:0005397 10.02 ESR1 HLA-DQA1 HLA-DQB1 HP IL1B IL6
5 endocrine/exocrine gland MP:0005379 10.01 ESR1 GLUD1 HLA-DQA1 HLA-DQB1 IL6 OXT
6 immune system MP:0005387 9.91 ESR1 HLA-DQA1 HLA-DQB1 HP IL1B IL6
7 integument MP:0010771 9.7 ESR1 IL1B IL6 OXT PGR SELE
8 liver/biliary system MP:0005370 9.43 ESR1 HLA-DQB1 HP IL6 SELE TNF
9 neoplasm MP:0002006 9.1 ESR1 HP IL1B IL6 PGR TNF

Drugs & Therapeutics for Endometritis

Drugs for Endometritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 96)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
2
Ofloxacin Approved Phase 4 82419-36-1 4583
3
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
4
Methylergonovine Approved Phase 4 113-42-8 8226
5
Oxytocin Approved, Vet_approved Phase 4 50-56-6 439302 53477758
6
Levonorgestrel Approved, Investigational Phase 4 797-63-7, 17489-40-6 13109
7
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
8
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
9
Metronidazole Approved Phase 4 443-48-1 4173
10 Pharmaceutical Solutions Phase 4
11 Renal Agents Phase 4
12 Cytochrome P-450 Enzyme Inhibitors Phase 4
13 Topoisomerase Inhibitors Phase 4
14 Anti-Infective Agents, Urinary Phase 4
15 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
16 Lactams Phase 4
17 beta-Lactams Phase 4
18 Contraceptives, Oral Phase 4
19 Contraceptive Agents Phase 4
20 Antiparasitic Agents Phase 4
21 Antimalarials Phase 4
22 Antiprotozoal Agents Phase 4
23 Gentamicins Phase 4
24 Clindamycin palmitate Phase 4
25 Clindamycin phosphate Phase 4
26
Povidone Approved Phase 3 9003-39-8
27
Povidone-iodine Approved Phase 3 25655-41-8
28
Iodine Approved, Investigational Phase 3 7553-56-2 807
29
Ampicillin Approved, Vet_approved Phase 2, Phase 3 69-53-4 6249
30
Copper Approved, Investigational Phase 3 7440-50-8 27099
31
Hydroxychloroquine Approved Phase 3 118-42-3 3652
32 Plasma Substitutes Phase 3
33 cadexomer iodine Phase 3
34 Blood Substitutes Phase 3
35 Dermatologic Agents Phase 2, Phase 3
36 Emollients Phase 2, Phase 3
37 Antirheumatic Agents Phase 3
38 Hormones Phase 3
39 Antibodies Phase 3
40 Immunoglobulins Phase 3
41 Antibodies, Antiphospholipid Phase 3
42
Ceftriaxone Approved Phase 2 73384-59-5 5479530 5361919
43
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
44
Cefoxitin Approved Phase 2 35607-66-0 441199
45
Cefotaxime Approved Phase 2 63527-52-6 456256 5742673
46 Anti-Infective Agents, Local Phase 2
47 Disinfectants Phase 2
48 Chlorhexidine gluconate Phase 2
49
Cephalexin Approved, Investigational, Vet_approved Phase 1 15686-71-2 27447
50
Ertapenem Approved, Investigational Phase 1 153832-46-3 150610

Interventional clinical trials:

(show top 50) (show all 103)
# Name Status NCT ID Phase Drugs
1 Preoperative Vaginal Cleansing With Povidone Iodine and the Risk of Post Cesarean Endometritis Unknown status NCT02693483 Phase 4 10% povidone iodine
2 Does Preoperative Vaginal Preparation With Povidone-iodine Before Cesarean Delivery Reduce the Risk of Endometritis? Completed NCT01437228 Phase 4 povidone- iodine solution.;placebo
3 Efficacy and Side-Effects of Two Dosing Regimens of Doxycycline at Surgical Abortion: A Randomized Double-Blind Trial Completed NCT00547170 Phase 4 Doxycycline pre-operatively;Doxycycline post-operatively
4 Antibiotic Prophylaxis for Postpartum Infections Following Caesarean Section Completed NCT02072798 Phase 4 Cefuroxime
5 SIGnificance of Routine Hysteroscopy Prior to a First 'in Vitro Fertilization'(IVF) Treatment Cycle Completed NCT01242852 Phase 4
6 Antibiotics During Intrauterine Balloon Tamponade Placement Recruiting NCT03478163 Phase 4 CeFAZolin 1000 MG;Clindamycin 900 MG in 6 ML Injection
7 Azithromycin With or Without Amoxicillin to Prevent Peripartum Infection and Sepsis in Laboring High-risk Women: 3-Arm RCT Recruiting NCT03248297 Phase 4 Azithromycin;Azithromycin and amoxicillin;Placebo
8 An Open-Lable Multicenter Prospective Non-Randomized Trial to Assess the Efficacy and Safety of Morinidazole With Levofloxacin and Sequential of Levofloxacin in Women With Pelvic Inflammatory Disease Recruiting NCT03391440 Phase 4 morinidazole
9 A Randomized Clinical Trial Between Clindamycin Once and Thrice a Day in Septic Abortion. Recruiting NCT02309346 Phase 4 Clindamycin
10 Controlled, Multicenter, Randomized Parallel Group Pilot Study With 2 Treatment Arms in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis (BV) Recruiting NCT02042287 Phase 4 Metronidazole
11 A Randomized Controlled Trial to Assess the Effectiveness of Multimodal Prophylactic Uterotonics in Patients Undergoing Non-Elective Cesarean Sections After a Trial of Labor Not yet recruiting NCT03904446 Phase 4 Methylergonovine;Normal Saline (placebo)
12 Experimental Study Examining Mirena IUD Insertion and Estimating Rates of Expulsion Immediately After Placental Delivery. Suspended NCT01230242 Phase 4
13 Treatment Utility of Postpartum Antibiotics in Chorioamnionitis Terminated NCT01585129 Phase 4 Postpartum Antibiotics;No postpartum antibiotics
14 Prolonged Treatment for Infected Abortion After Hospital Discharge. Terminated NCT00376493 Phase 4 metronidazole and doxycycline
15 A Randomized Clinical Trial of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis Withdrawn NCT01721616 Phase 4 Azithromycin;Cefazolin
16 Antibiotic Prophylaxis and Intervention for Postpartum Infections Following Caesarean Section Withdrawn NCT02009098 Phase 4 Cefuroxime
17 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term - a Randomized Controlled Trial Completed NCT01633294 Phase 2, Phase 3 Ampicillin + gentamicin
18 Chlorhexidine Gluconate vs Povidone-Iodine Vaginal Cleansing Solution Prior to Cesarean Delivery: A Randomized Comparator Controlled Trial Completed NCT02915289 Phase 3
19 Back to BASICS: Boric Acid, Alternate Solution for Intravaginal Colonization, Comparing Intravaginal Metronidazole to Boric Acid in Women Symptomatic for Bacterial Vaginosis Completed NCT00799214 Phase 2, Phase 3 Placebo;Boric acid;Metronidazole
20 A Phase 3, Prospective, Multi-Center, Single-Arm, Open-Label Study to Evaluate VeraCept™, a Long-Acting Reversible Intrauterine Contraceptive for Contraceptive Efficacy, Safety, and Tolerability Recruiting NCT03633799 Phase 3 VeraCept
21 Prévention Des Fausses Couches Spontanées Répétées Par Hydroxychloroquine. Essai thérapeutique Multicentrique, randomisé, en Double Insu, Contre Placebo Recruiting NCT03165136 Phase 3 Hydroxychloroquine;Placebo
22 A Randomized Trial to Investigate if a Pre-operative Wash With Chlorhexidine vs Povidone-iodine Vaginal Scrub Decreases Infectious Morbidity in Patients Undergoing Cesarean Section After Ruptured Membranes Not yet recruiting NCT03925155 Phase 3 EZ scrub vaginal chlorhexidine 4% solution;10% provodine-iodine vaginal preparation
23 The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section: Randomized Comparative Study Unknown status NCT02742948 Phase 2 ceftriaxone
24 Is More Than One Dose of Misoprostol Needed to Expedite Vaginal Delivery in a Patient With an Unripe Cervix? Unknown status NCT02680314 Phase 2 Misoprostol
25 Intrauterine Infusion of Autologous Platelet-Rich Plasma (PRP) in Women With Thin Endometrium Undergoing Embryo-transfer. Recruiting NCT03067623 Phase 2 PRP
26 A Randomized Trial to Determine if a Pre-operative Wash With a Chlorhexidine Gluconate Cloth and Chlorhexidine Gluconate Vaginal Scrub Reduces Infectious Morbidity in Patients Undergoing Cesarean Section After Labor Recruiting NCT03423147 Phase 2 2% chlorhexidine gluconate cloth;4% Chlorhexidine gluconate vaginal scrub
27 Azithromycin-based Extended-spectrum Prophylaxis in Scheduled Cesarean Deliveries Not yet recruiting NCT03960970 Phase 2 Azithromycin 500 mg;Mefoxin 2g
28 Comparative Controlled Trial of Treatment of Minor Unexpected Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy Screening in Women Indicated for IVF Terminated NCT00830401 Phase 2 Ofloxacinum/Doxycycline
29 Prophylactic Antibiotics After Cesarean Recruiting NCT03187106 Phase 1 Cephalexin;Placebo;Metronidazole
30 Safety and Therapeutic Effect of Human Amniotic Epithelial Cells in Severe Refractory Asherman's Syndrome Not yet recruiting NCT03223454 Phase 1
31 Pharmacokinetics and Safety of Ertapenem in the Postpartum Period Terminated NCT01587495 Phase 1 Ertapenem
32 Curcumin Supplementation for Gynecological Diseases Including Pelvic Inflammatory Disease Endometritis, Endometriosis: A Pilot Study Unknown status NCT03016039
33 Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth Unknown status NCT01945450 Antibiotic prophylaxis;Ampicillin;Gentamycin;Clindamycin
34 The Role of Antibiotic Prophylaxis in Immediate Versus Delayed Induction in Term-PROM - a Randomized Controlled Trial Unknown status NCT02985086 Cefoxitin;oxytocin/misoprostol
35 A Multicenter Analysis of Levonorgestrel-Intrauterine System (LNG-IUS) Use in the Postpartum Period Unknown status NCT01161095
36 The Use of Cranberries in Women With Preterm Premature Rupture of Membranes Unknown status NCT00247104 Cranberries - Vaccinium macrocarpon
37 Use of 48 Hour Course of Antibiotics to Prevent Surgical Site Infection in Obese Patients Undergoing Cesarean Delivery Unknown status NCT01194115 cephalexin & metronidazole;placebo
38 Evaluation of a Diagnostic Kit for the Detection of Serum Antibodies Anti Genital Mycoplasma in High Risk Pregnant Women Unknown status NCT01281319
39 Cervical Ripening in Premature Rupture of Membranes Unknown status NCT02314728 Misoprostol;Oxytocin
40 Relation Between Internal Vaginal Douching and Vaginal Infections in Intrauterine Contraceptive Device Users Unknown status NCT03261804
41 Core-temperature Monitoring in Patients With PPROM for Early Detection of Chorioamnionitis - a Pilot Study Unknown status NCT02125708
42 Prevalence of Chronic Endometritis in Patients With Recurrent Miscarriages or Repeated Implantation Failures in In-vitro Fertilization Completed NCT01762098
43 Efficacy of Intravaginal Dead Sea Peloid Gel Administration in Complex Treatment of Chronic Endometritis and Reproductive Disorders: Randomized Placebo-controlled Prospective Study Completed NCT02680275 Dead Sea Peloid Gel
44 A Randomized, Double-Blind, Placebo Controlled Trial of Cefazolin Given Either 30 Minutes Prior to Cesarean Section or at Cord Clamping Completed NCT00330278 Cefazolin
45 Prevalence of Chronic Endometritis in Severe Intrauterine Adhesions and Role of Chronic Endometritis in Postoperative Recurrence of Severe Intrauterine Completed NCT02744807
46 Antibiotic Prophylaxis in Ragged Placental Membranes: A Prospective, Multicenter, Randomized Trial Completed NCT03459599 Prophylactic antibiotics
47 Supplemental Perioperative Oxygen to Reduce the Incidence of Post-Cesarean Endometritis and Wound Infection Completed NCT00670020
48 Characterization of Novel Organisms in the Genital Tract of Women With PID and Determination of Their Association With Endometritis. Completed NCT01236131
49 Uterine Flora During Elective and Urgent Cesarean Sections and Its Relationship to Postpartum Complications. Completed NCT00500019
50 The Pharmacokinetics of Azithromycin Prophylaxis for Cesarean Delivery Completed NCT01464840 Azithromycin

Search NIH Clinical Center for Endometritis

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Cefotaxime
Cefoxitin
Clindamycin
Ertapenem
Metronidazole

Cochrane evidence based reviews: endometritis

Genetic Tests for Endometritis

Anatomical Context for Endometritis

MalaCards organs/tissues related to Endometritis:

41
Uterus, Placenta, Colon, Neutrophil, Skin, Testes, Cervix

Publications for Endometritis

Articles related to Endometritis:

(show top 50) (show all 3506)
# Title Authors PMID Year
1
Effects of the administration of oxytocin or carbetocin to dairy cows at parturition on their subsequent fertility. 9 38
19933542 2009
2
WITHDRAWN: Oxytocin for prelabour rupture of membranes at or near term. 9 38
17636608 2007
3
Oxytocin for prelabour rupture of membranes at or near term. 9 38
10796159 2000
4
Premature rupture of membranes at term: a meta-analysis of three management schemes. 9 38
9170488 1997
5
Clinical amnionitis and endometritis in patients with premature rupture of membranes: endocervical prostaglandin E2 gel versus oxytocin for induction of labor. 9 38
8841214 1996
6
Oxytocin enhances clearance of radiocolloid from the uterine lumen of reproductively normal mares and mares susceptible to endometritis. 9 38
8575394 1994
7
Investigations into the use of exogenous oxytocin for promoting uterine drainage in mares susceptible to endometritis. 9 38
1897091 1991
8
Daily gentamicin using ideal body weight demonstrates lower risk of postpartum endometritis and increased chance of successful outcome compared with traditional 8-hour dosing for the treatment of intrapartum chorioamnionitis. 38
29642754 2019
9
The impact of time of delivery on gestations complicated by preterm premature rupture of membranes: daytime versus nighttime. 38
29631461 2019
10
Association of Ureaplasma diversum with reproductive disease in cattle. 38
31131738 2019
11
Xanthogranulomatous Salpingitis. 38
31433377 2019
12
Subclinical endometritis in estrual buffaloes: diagnosis, prevalence and impact on reproductive performance. 38
31376061 2019
13
Characterization of circulating plasma proteins in dairy cows with cytological endometritis. 38
31233901 2019
14
Confirmation of chronic endometritis in repeated implantation failure and success outcome in IVF-ET after intrauterine delivery of the combined administration of antibiotic and dexamethasone. 38
31373128 2019
15
Temporal efficacy of antimicrobials against aerobic bacteria isolated from equine endometritis: an Italian retrospective analysis (2010-2017). 38
31409748 2019
16
Differential expression of endometrial toll-like receptors (TLRs) and antimicrobial peptides (AMPs) in the buffalo (Bubalus bubalis) with endometritis. 38
31407222 2019
17
Differences in outcomes between cesarean section in the second versus the first stages of labor. 38
29471705 2019
18
Azithromycin-based Extended-Spectrum Antibiotic Prophylaxis for Cesarean: Role of Placental Colonization with Genital Ureaplasmas and Mycoplasmas. 38
30500967 2019
19
Prostaglandin E2 promotes nitric oxide synthase 2, platelet-activating factor receptor, and matrix metalloproteinase-2 expression in Escherichia coli-challenged ex vivo endometrial explants via the prostaglandin E2 receptor 4/protein kinase a signaling pathway. 38
31136957 2019
20
TREM-1 deficiency attenuates the inflammatory responses in LPS-induced murine endometritis. 38
31365951 2019
21
Therapeutic effects of resveratrol in Escherichia coli-induced rat endometritis model. 38
31367863 2019
22
Chronic endometritis is associated with an altered microbiome, but what about treatment and clinical outcomes? 38
31371046 2019
23
Acute Endometritis due to Taylorella equigenitalis Transmission by Insemination of Cryopreserved Stallion Semen. 38
31203971 2019
24
Antibiotic prophylaxis in ragged placental membranes: a prospective, multicentre, randomized trial. 38
31296180 2019
25
Unified diagnostic criteria for chronic endometritis at fluid hysteroscopy: proposal and reliability evaluation through an international randomized-controlled observer study. 38
31104760 2019
26
Doppler sonography of uterine blood flow at mid-oestrus during different degree of clinical endometritis in dairy cows. 38
31306513 2019
27
Endometrial microbiota in infertile women with and without chronic endometritis as diagnosed using a quantitative and reference range-based method. 38
31327470 2019
28
Predicting the probability of conception in dairy cows with clinical endometritis based on a combination of anamnestic information and examination results. 38
31326659 2019
29
Salpingitis Impairs Bovine Tubal Function and Sperm-Oviduct Interaction. 38
31350463 2019
30
Adverse Maternal Outcomes Associated with Uterine Extensions at the Time of Cesarean Delivery. 38
30646423 2019
31
Supplementing rumen-protected methionine to lactating multiparous dairy cows did not improve reproductive performance. 38
31301254 2019
32
Investigating the Suitability of a Laboratory Mouse Model to Study the Pathogenesis of Abortifacient Campylobacter jejuni. 38
30895909 2019
33
Women's perspectives on caesarean section recovery, infection and the PREPS trial: a qualitative pilot study. 38
31307417 2019
34
Implementation of vaginal cleansing prior to cesarean delivery to decrease endometritis rates. 38
29343134 2019
35
Pro-inflammatory cytokine expression studies of subclinical and clinical endometritis in endometrial tissues of buffaloes. 38
30684222 2019
36
Exosome-derived uterine microRNAs isolated from cows with endometritis impede blastocyst development. 38
31196738 2019
37
Impact of endometritis on post-partum ovarian cyclicity in dairy cows. 38
31113569 2019
38
Targeted transcript analysis revealed association of suboptimal expression of certain endometrial immunity-related genes with disparate uterine diseases in zebu cows. 38
31197726 2019
39
Uterine endometrial cytology, biopsy, bacteriology, and serum C-reactive protein in clinically healthy diestrus bitches. 38
30974392 2019
40
Multiple Myeloma 1 Transcription Factor Is Superior to CD138 as a Marker of Plasma Cells in Endometrium. 38
30482071 2019
41
Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial. 38
31097213 2019
42
Chorioamnionitis and Infectious Complications after Vaginal Delivery. 38
31238347 2019
43
Peripartum infectious morbidity in women with preeclampsia. 38
31167579 2019
44
Preterm Prelabor Rupture of Membranes: Outcomes with Expectant Management until 34 versus 35 Weeks. 38
30553236 2019
45
Endometritis and Bacteremia With a New Delhi Metallo-Beta-Lactamase 1 (NDM-1)-containing Organism in a Remote Traveler. 38
30922705 2019
46
Evidence for Increased Content of PGF2α, PGE2, and 6-keto-PGF1α in Endometrial Tissue Cultures From Heavy Draft Mares in Anestrus With Endometritis. 38
31133302 2019
47
Short communication: Proinflammatory gene expression relative to the collection technique of endometrial samples from cows with and without subclinical endometritis. 38
30981492 2019
48
Endometritis affects chemical coding of the dorsal root ganglia neurons supplying uterus in the sexually mature gilts. 38
31078789 2019
49
Effects of follicular fluid of preovulatory follicles of repeat breeder dairy cows with subclinical endometritis on oocyte developmental competence. 38
31005360 2019
50
Regulatory roles of PGE2 in LPS-induced tissue damage in bovine endometrial explants. 38
30930248 2019

Variations for Endometritis

Expression for Endometritis

Search GEO for disease gene expression data for Endometritis.

Pathways for Endometritis

Pathways related to Endometritis according to GeneCards Suite gene sharing:

(show all 38)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.26 TNF IL6 IL1B HLA-DQB1 HLA-DQA1 CXCL1
2
Show member pathways
12.78 TNF IL6 IL1B HLA-DQB1 HLA-DQA1
3
Show member pathways
12.52 TNF IL6 IL1B HLA-DQB1 HLA-DQA1
4
Show member pathways
12.49 TNF IL6 IL1B CXCL1
5 12.28 TNF IL6 HLA-DQB1 HLA-DQA1
6
Show member pathways
12.25 TNF IL6 IL1B CXCL1
7
Show member pathways
12.19 TNF IL1B HLA-DQB1 HLA-DQA1
8 12.11 TNF IL6 IL1B HLA-DQB1 HLA-DQA1
9
Show member pathways
11.96 TNF IL6 IL1B
10
Show member pathways
11.94 TNF IL6 IL1B
11 11.93 TNF IL6 IL1B CXCL1
12 11.89 TNF IL6 IL1B
13 11.85 IL6 IL1B CXCL1
14 11.84 TNF SELE IL6 IL1B
15 11.82 TNF IL6 IL1B CXCL1
16 11.73 IL6 IL1B CXCL1
17 11.7 TNF SELE IL6 IL1B CXCL1
18 11.69 TNF IL6 IL1B
19 11.67 TNF IL6 IL1B
20 11.65 TNF IL6 IL1B CXCL1
21 11.6 TNF IL6 IL1B
22
Show member pathways
11.58 TNF SELE IL6 IL1B
23 11.54 TNF IL6 IL1B HLA-DQB1 HLA-DQA1
24 11.48 TNF IL6 IL1B CXCL1
25 11.46 TNF IL6 HP
26 11.42 TNF IL6 IL1B
27 11.4 TNF SELE IL6 IL1B
28 11.36 TNF IL6 IL1B CXCL1
29 11.3 TNF IL6 IL1B
30 11.25 TNF IL6 IL1B
31 11.23 TNF IL6 IL1B
32 11.19 TNF SELE IL6 IL1B
33 11.14 TNF IL6 IL1B CXCL1
34 11.07 TNF IL6 IL1B HLA-DQB1 HLA-DQA1 CXCL1
35 11.04 TNF PGR IL1B
36 10.95 TNF IL6
37 10.87 TNF IL1B
38 10.72 TNF IL6 IL1B CXCL1

GO Terms for Endometritis

Cellular components related to Endometritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.23 TNF SELE OXT MIRLET7C IL6 IL1B
2 MHC class II protein complex GO:0042613 8.96 HLA-DQB1 HLA-DQA1

Biological processes related to Endometritis according to GeneCards Suite gene sharing:

(show all 28)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.88 TNF IL6 IL1B CXCL1
2 inflammatory response GO:0006954 9.83 TNF SELE IL6 IL1B CXCL1
3 cellular response to lipopolysaccharide GO:0071222 9.76 TNF IL6 IL1B CXCL1
4 regulation of inflammatory response GO:0050727 9.73 TNF SELE ESR1
5 immune response GO:0006955 9.73 TNF IL6 IL1B HLA-DQB1 HLA-DQA1 CXCL1
6 positive regulation of interleukin-6 production GO:0032755 9.7 TNF IL6 IL1B
7 positive regulation of DNA-binding transcription factor activity GO:0051091 9.67 TNF IL6 IL1B ESR1
8 positive regulation of chemokine production GO:0032722 9.64 TNF IL6
9 leukocyte tethering or rolling GO:0050901 9.63 TNF SELE
10 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.63 TNF IL1B
11 negative regulation of lipid catabolic process GO:0050995 9.62 TNF IL1B
12 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.62 TNF IL1B
13 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.61 TNF IL1B
14 response to estradiol GO:0032355 9.61 OXT ESR1
15 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 9.6 HLA-DQB1 HLA-DQA1
16 negative regulation of lipid storage GO:0010888 9.58 TNF IL6
17 positive regulation of chemokine biosynthetic process GO:0045080 9.57 TNF IL1B
18 regulation of establishment of endothelial barrier GO:1903140 9.55 TNF IL1B
19 positive regulation of prostaglandin secretion GO:0032308 9.54 OXT IL1B
20 positive regulation of fever generation GO:0031622 9.51 TNF IL1B
21 negative regulation of neurogenesis GO:0050768 9.5 TNF IL6 IL1B
22 sequestering of triglyceride GO:0030730 9.49 TNF IL1B
23 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.4 TNF IL1B
24 positive regulation of glial cell proliferation GO:0060252 9.33 TNF IL6 IL1B
25 chronic inflammatory response to antigenic stimulus GO:0002439 9.18 TNF
26 response to glucocorticoid GO:0051384 9.13 TNF OXT IL6
27 positive regulation of neuroinflammatory response GO:0150078 8.8 TNF IL6 IL1B
28 positive regulation of transcription by RNA polymerase II GO:0045944 10.07 TNF PGR MIRLET7C IL6 IL1B ESR1

Molecular functions related to Endometritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MHC class II receptor activity GO:0032395 8.96 HLA-DQB1 HLA-DQA1
2 cytokine activity GO:0005125 8.92 TNF IL6 IL1B CXCL1

Sources for Endometritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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