MCID: END046
MIFTS: 49

Endometritis

Categories: Reproductive diseases

Aliases & Classifications for Endometritis

MalaCards integrated aliases for Endometritis:

Name: Endometritis 12 54 43 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:1002
MeSH 43 D004716
NCIt 49 C26764
SNOMED-CT 67 78623009
UMLS 71 C0014179

Summaries for Endometritis

Disease Ontology : 12 An endometrial disease that is characterized by inflammation of the endometrium.

MalaCards based summary : Endometritis is related to granulomatous endometritis and salpingitis. An important gene associated with Endometritis is OXT (Oxytocin/Neurophysin I Prepropeptide), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Levofloxacin and Ofloxacin have been mentioned in the context of this disorder. Affiliated tissues include uterus, placenta and colon, and related phenotypes are cardiovascular system and hematopoietic system

Wikipedia : 74 Endometritis is inflammation of the inner lining of the uterus (endometrium). Symptoms may include... more...

Related Diseases for Endometritis

Diseases in the Endometritis family:

Acute Endometritis

Diseases related to Endometritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 626)
# Related Disease Score Top Affiliating Genes
1 granulomatous endometritis 34.4 SDC1 PGR ESR1
2 salpingitis 32.7 TNF TLR2 SIGLEC5
3 myoma 30.9 PGR OXT ESR1
4 endometriosis 30.8 PGR IL6 IL1B ESR1 CXCL8
5 conjunctivitis 30.7 TNF IL6 CXCL8
6 streptococcal toxic-shock syndrome 30.7 TNF IL6 CXCL8
7 leiomyoma, uterine 30.6 PGR OXT MIRLET7C MIR27A ESR1
8 cytomegalovirus infection 30.6 TNF IL6 IL1B CXCL8
9 vaginal discharge 30.6 TNF PGR OXT IL6 IL1B HP
10 chlamydia 30.6 TNF TLR4 TLR2 IL6 IL1B CXCL8
11 meningoencephalitis 30.6 TNF IL6 IL1B
12 trichomoniasis 30.5 TNF IL6 IL1B CXCL8
13 cellulitis 30.5 TNF IL6 IL1B
14 pelvic inflammatory disease 30.5 TLR4 TLR2 SIGLEC5 LACTB HLA-DQA1
15 chorioamnionitis 30.5 TNF TLR4 OXT IL6 IL1B CXCL8
16 hemorrhagic cystitis 30.4 TNF TLR4 IL1B
17 adenomyosis 30.3 PGR OXT IL6 ESR1 CXCL8
18 diverticulitis 30.3 TNF SDC1 IL6
19 exanthem 30.3 TNF IL6 IL1B CXCL8
20 bacterial vaginosis 30.2 TNF TLR4 TLR2 IL6 IL1B CXCL8
21 mastitis 30.2 TLR2 OXT IL6 HP CXCL8
22 hashimoto thyroiditis 30.2 TNF IL6 IL1B HLA-DQB1 HLA-DQA1
23 ovarian disease 30.2 TNF PGR MIR27A IL6 ESR1
24 cervicitis 30.2 TNF TLR4 TLR2 IL6 IL1B CXCL8
25 peritonitis 30.1 TNF TLR4 TLR2 IL6 IL1B CXCL8
26 cystitis 30.0 TNF TLR4 IL6 CXCL8 CXCL1
27 ectopic pregnancy 30.0 TLR2 PGR IL1B
28 tuberculous meningitis 30.0 TNF TLR2 CXCL8
29 stomatitis 29.8 TNF TLR4 IL6 IL1B CXCL8
30 appendicitis 29.8 TNF TLR4 IL6 IL1B CXCL8
31 pyelonephritis 29.8 TNF TLR4 IL6 IL1B CXCL8
32 haemophilus influenzae 29.8 TNF TLR2 LACTB CXCL8
33 toxic shock syndrome 29.8 TNF TLR4 TLR2 IL6 IL1B CXCL8
34 leptospirosis 29.7 TNF TLR2 IL6 IL1B CXCL8
35 q fever 29.7 TNF TLR4 TLR2 IL6 IL1B
36 bacteriuria 29.6 TLR4 TLR2 IL6 CXCL8 CXCL1
37 pre-eclampsia 29.6 TNF TLR4 OXT IL6 IL1B CXCL8
38 endocarditis 29.6 TNF TLR2 LACTB IL6 CXCL8
39 vaginitis 29.5 TNF TLR4 TLR2 IL6 IL1B ESR1
40 urethritis 29.5 TNF TLR4 TLR2 IL6 IL1B CXCL8
41 bacterial infectious disease 29.5 TNF TLR4 TLR2 IL6 IL1B CXCL8
42 acute cystitis 29.4 TNF TLR4 TLR2 IL6 IL1B CXCL8
43 candidiasis 29.2 TNF TLR4 TLR2 IL6 IL1B CXCL8
44 viral infectious disease 29.2 TNF TLR4 TLR2 IL6 IL1B CXCL8
45 pulmonary tuberculosis 29.0 TNF TLR4 TLR2 IL6 IL1B HP
46 measles 29.0 TNF TLR4 TLR2 IL6 IL1B HLA-DQA1
47 eye disease 29.0 TNF TLR4 TLR2 MIR27A IL6 IL1B
48 meningitis 28.9 TNF TLR4 TLR2 LACTB IL6 IL1B
49 reactive arthritis 28.9 TNF TLR4 TLR2 IL6 IL1B HP
50 tonsillitis 28.8 TNF TLR4 TLR2 LACTB IL6 IL1B

Graphical network of the top 20 diseases related to Endometritis:



Diseases related to Endometritis

Symptoms & Phenotypes for Endometritis

MGI Mouse Phenotypes related to Endometritis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.14 ESR1 HLA-DQB1 HP IL1B IL6 LACTB
2 hematopoietic system MP:0005397 10.1 CXCL13 ESR1 HLA-DQA1 HLA-DQB1 HP IL1B
3 endocrine/exocrine gland MP:0005379 10.07 ESR1 GLUD1 HLA-DQA1 HLA-DQB1 IL6 OXT
4 homeostasis/metabolism MP:0005376 10.07 ESR1 GLUD1 HLA-DQB1 HP IL1B IL6
5 immune system MP:0005387 9.93 CXCL13 ESR1 HLA-DQA1 HLA-DQB1 HP IL1B
6 integument MP:0010771 9.61 ESR1 IL1B IL6 OXT PGR SDC1
7 neoplasm MP:0002006 9.28 ESR1 HP IL1B IL6 PGR SDC1

Drugs & Therapeutics for Endometritis

Drugs for Endometritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 97)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
2
Ofloxacin Approved Phase 4 82419-36-1 4583
3
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
4
Methylergonovine Approved Phase 4 113-42-8 8226
5
Oxytocin Approved, Vet_approved Phase 4 50-56-6 53477758 439302
6
Vancomycin Approved Phase 4 1404-90-6 14969 441141
7
Levonorgestrel Approved, Investigational Phase 4 797-63-7, 17489-40-6 13109
8
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
9
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
10
Metronidazole Approved Phase 4 443-48-1 4173
11 Pharmaceutical Solutions Phase 4
12 beta-Lactams Phase 4
13 Lactams Phase 4
14 Anesthetics Phase 4
15 Cephalosporins Phase 4
16 Contraceptive Agents Phase 4
17 Contraceptives, Oral Phase 4
18 Clindamycin phosphate Phase 4
19 Clindamycin palmitate Phase 4
20 Gentamicins Phase 4
21 Antiparasitic Agents Phase 4
22 Antiprotozoal Agents Phase 4
23 Antitubercular Agents Phase 4
24 Antimalarials Phase 4
25
Iodine Approved, Investigational Phase 3 7553-56-2 807
26
Povidone Approved Phase 3 9003-39-8
27
Povidone-iodine Approved Phase 3 25655-41-8
28
Ampicillin Approved, Vet_approved Phase 2, Phase 3 69-53-4 6249
29
Hydroxychloroquine Approved Phase 3 118-42-3 3652
30
Copper Approved, Investigational Phase 3 7440-50-8 27099
31 Plasma Substitutes Phase 3
32 cadexomer iodine Phase 3
33 Blood Substitutes Phase 3
34 Emollients Phase 2, Phase 3
35 Antirheumatic Agents Phase 3
36 Immunoglobulins Phase 3
37 Antibodies Phase 3
38 Antibodies, Antiphospholipid Phase 3
39 Copper Supplement Phase 3
40 Hormones Phase 3
41 Trace Elements Phase 3
42 Nutrients Phase 3
43 Micronutrients Phase 3
44
Ceftriaxone Approved Phase 2 73384-59-5 5361919 5479530
45
leucovorin Approved Phase 2 58-05-9 6006 143
46
Methotrexate Approved Phase 2 59-05-2, 1959-05-2 126941
47
Cefoxitin Approved Phase 2 35607-66-0 441199
48
Cefotaxime Approved Phase 2 63527-52-6 5742673 456256
49
Chlorhexidine Approved, Vet_approved Phase 2 55-56-1 9552079 2713
50
Dinoprostone Approved Phase 2 363-24-6 5280360

Interventional clinical trials:

(show top 50) (show all 118)
# Name Status NCT ID Phase Drugs
1 Preoperative Vaginal Cleansing With Povidone Iodine and the Risk of Post Cesarean Endometritis Unknown status NCT02693483 Phase 4 10% povidone iodine
2 An Open-Lable Multicenter Prospective Non-Randomized Trial to Assess the Efficacy and Safety of Morinidazole With Levofloxacin and Sequential of Levofloxacin in Women With Pelvic Inflammatory Disease Unknown status NCT03391440 Phase 4 morinidazole
3 A Randomized Clinical Trial Between Clindamycin Once and Thrice a Day in Septic Abortion. Unknown status NCT02309346 Phase 4 Clindamycin
4 Does Preoperative Vaginal Preparation With Povidone-iodine Before Cesarean Delivery Reduce the Risk of Endometritis? Completed NCT01437228 Phase 4 povidone- iodine solution.;placebo
5 Efficacy and Side-Effects of Two Dosing Regimens of Doxycycline at Surgical Abortion: A Randomized Double-Blind Trial Completed NCT00547170 Phase 4 Doxycycline pre-operatively;Doxycycline post-operatively
6 Antibiotic Prophylaxis for Postpartum Infections Following Caesarean Section Completed NCT02072798 Phase 4 Cefuroxime
7 SIGnificance of Routine Hysteroscopy Prior to a First 'in Vitro Fertilization'(IVF) Treatment Cycle Completed NCT01242852 Phase 4
8 Antibiotics During Intrauterine Balloon Tamponade Placement Recruiting NCT03478163 Phase 4 CeFAZolin 1000 MG;Clindamycin 900 MG in 6 ML Injection
9 Azithromycin With or Without Amoxicillin to Prevent Peripartum Infection and Sepsis in Laboring High-risk Women: 3-Arm RCT Recruiting NCT03248297 Phase 4 Azithromycin;Azithromycin and amoxicillin;Placebo
10 A Randomized Controlled Trial to Assess the Effectiveness of Multimodal Prophylactic Uterotonics in Patients Undergoing Non-Elective Cesarean Sections After a Trial of Labor Recruiting NCT03904446 Phase 4 Methylergonovine;Normal Saline (placebo)
11 Controlled, Multicenter, Randomized Parallel Group Pilot Study With 2 Treatment Arms in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis (BV) Recruiting NCT02042287 Phase 4 Metronidazole
12 First Tier Versus Second Tier Antibiotics for Surgical Site Infections Following Hysterectomy In the Patients With a Beta-Lactam Allergy: A Prospective, Randomized, Single-Blinded Clinical Trial Not yet recruiting NCT04401553 Phase 4 cephalosporin;Second tier antibiotic (Vancomycin)
13 Experimental Study Examining Mirena IUD Insertion and Estimating Rates of Expulsion Immediately After Placental Delivery. Suspended NCT01230242 Phase 4
14 Treatment Utility of Postpartum Antibiotics in Chorioamnionitis Terminated NCT01585129 Phase 4 Postpartum Antibiotics;No postpartum antibiotics
15 Prolonged Treatment for Infected Abortion After Hospital Discharge. Terminated NCT00376493 Phase 4 metronidazole and doxycycline
16 A Randomized Clinical Trial of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis Withdrawn NCT01721616 Phase 4 Azithromycin;Cefazolin
17 Antibiotic Prophylaxis and Intervention for Postpartum Infections Following Caesarean Section Withdrawn NCT02009098 Phase 4 Cefuroxime
18 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term - a Randomized Controlled Trial Completed NCT01633294 Phase 2, Phase 3 Ampicillin + gentamicin
19 Chlorhexidine Gluconate vs Povidone-Iodine Vaginal Cleansing Solution Prior to Cesarean Delivery: A Randomized Comparator Controlled Trial Completed NCT02915289 Phase 3
20 Back to BASICS: Boric Acid, Alternate Solution for Intravaginal Colonization, Comparing Intravaginal Metronidazole to Boric Acid in Women Symptomatic for Bacterial Vaginosis Completed NCT00799214 Phase 2, Phase 3 Placebo;Boric acid;Metronidazole
21 Prévention Des Fausses Couches Spontanées Répétées Par Hydroxychloroquine. Essai thérapeutique Multicentrique, randomisé, en Double Insu, Contre Placebo Recruiting NCT03165136 Phase 3 Hydroxychloroquine;Placebo
22 A Phase 3, Prospective, Multi-Center, Single-Arm, Open-Label Study to Evaluate VeraCept™, a Long-Acting Reversible Intrauterine Contraceptive for Contraceptive Efficacy, Safety, and Tolerability Active, not recruiting NCT03633799 Phase 3 VeraCept
23 A Randomized Trial to Investigate if a Pre-operative Wash With Chlorhexidine vs Povidone-iodine Vaginal Scrub Decreases Infectious Morbidity in Patients Undergoing Cesarean Section After Ruptured Membranes Not yet recruiting NCT03925155 Phase 3 EZ scrub vaginal chlorhexidine 4% solution;10% provodine-iodine vaginal preparation
24 The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section: Randomized Comparative Study Unknown status NCT02742948 Phase 2 ceftriaxone
25 Is More Than One Dose of Misoprostol Needed to Expedite Vaginal Delivery in a Patient With an Unripe Cervix? Unknown status NCT02680314 Phase 2 Misoprostol
26 Azithromycin-based Extended-spectrum Prophylaxis in Scheduled Cesarean Deliveries Recruiting NCT03960970 Phase 2 Azithromycin 500 mg;Mefoxin 2g
27 The Impact of Chlorhexidine Preoperative Vaginal Preparation in Reducing the Post-cesarean Endometritis and Sepsis for Cases in Labor. A Randomized Controlled Trial Recruiting NCT04385680 Phase 1, Phase 2 Chlorhexidine Gluconate vaginal solution 0.05%
28 A Randomized Trial to Determine if a Pre-operative Wash With a Chlorhexidine Gluconate Cloth and Chlorhexidine Gluconate Vaginal Scrub Reduces Infectious Morbidity in Patients Undergoing Cesarean Section After Labor Recruiting NCT03423147 Phase 2 2% chlorhexidine gluconate cloth;4% Chlorhexidine gluconate vaginal scrub
29 Intrauterine Infusion of Autologous Platelet-Rich Plasma (PRP) in Women With Thin Endometrium Undergoing Embryo-transfer. Recruiting NCT03067623 Phase 2 PRP
30 Administration of Prostaglandin Gel for Cervical Priming During Induction of Labour Every 12 Hours Versus 24 Hours: a Randomized Superiority Controlled Trial Recruiting NCT04413890 Phase 2 Dinoprostone vaginal gel
31 Fertility Restoration Using Autologous Adipose Tissue Derived Mesenchymal Stem Cells Not yet recruiting NCT04432467 Phase 1, Phase 2
32 Comparative Controlled Trial of Treatment of Minor Unexpected Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy Screening in Women Indicated for IVF Terminated NCT00830401 Phase 2 Ofloxacinum/Doxycycline
33 Prophylactic Antibiotics After Cesarean Recruiting NCT03187106 Phase 1 Cephalexin;Placebo;Metronidazole
34 Safety and Therapeutic Effect of Human Amniotic Epithelial Cells in Severe Refractory Asherman's Syndrome Not yet recruiting NCT03223454 Phase 1
35 Pharmacokinetics and Safety of Ertapenem in the Postpartum Period Terminated NCT01587495 Phase 1 Ertapenem
36 Curcumin Supplementation for Gynecological Diseases Including Pelvic Inflammatory Disease Endometritis, Endometriosis: A Pilot Study Unknown status NCT03016039
37 Vaginal Antimicrobacterial Preparation Before Cesarean Secation for Endometritis Prevention Unknown status NCT03093194
38 Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth Unknown status NCT01945450 Antibiotic prophylaxis;Ampicillin;Gentamycin;Clindamycin
39 The Role of Antibiotic Prophylaxis in Immediate Versus Delayed Induction in Term-PROM - a Randomized Controlled Trial Unknown status NCT02985086 Cefoxitin;oxytocin/misoprostol
40 A Multicenter Analysis of Levonorgestrel-Intrauterine System (LNG-IUS) Use in the Postpartum Period Unknown status NCT01161095
41 The Use of Cranberries in Women With Preterm Premature Rupture of Membranes Unknown status NCT00247104 Cranberries - Vaccinium macrocarpon
42 Evaluation of a Diagnostic Kit for the Detection of Serum Antibodies Anti Genital Mycoplasma in High Risk Pregnant Women Unknown status NCT01281319
43 Use of 48 Hour Course of Antibiotics to Prevent Surgical Site Infection in Obese Patients Undergoing Cesarean Delivery Unknown status NCT01194115 cephalexin & metronidazole;placebo
44 Routine Cervical Dilatation at the Non-labor Caesarean Section and Its Influence on Postoperative Pain: A Randomised Controlled Trial Unknown status NCT03513237
45 Cervical Ripening in Premature Rupture of Membranes Unknown status NCT02314728 Misoprostol;Oxytocin
46 Relation Between Internal Vaginal Douching and Vaginal Infections in Intrauterine Contraceptive Device Users Unknown status NCT03261804
47 Core-temperature Monitoring in Patients With PPROM for Early Detection of Chorioamnionitis - a Pilot Study Unknown status NCT02125708
48 Prevalence of Chronic Endometritis in Patients With Recurrent Miscarriages or Repeated Implantation Failures in In-vitro Fertilization Completed NCT01762098
49 Efficacy of Intravaginal Dead Sea Peloid Gel Administration in Complex Treatment of Chronic Endometritis and Reproductive Disorders: Randomized Placebo-controlled Prospective Study Completed NCT02680275 Dead Sea Peloid Gel
50 A Randomized, Double-Blind, Placebo Controlled Trial of Cefazolin Given Either 30 Minutes Prior to Cesarean Section or at Cord Clamping Completed NCT00330278 Cefazolin

Search NIH Clinical Center for Endometritis

Cochrane evidence based reviews: endometritis

Genetic Tests for Endometritis

Anatomical Context for Endometritis

MalaCards organs/tissues related to Endometritis:

40
Uterus, Placenta, Colon, Neutrophil, Testes, Skin, Cervix

Publications for Endometritis

Articles related to Endometritis:

(show top 50) (show all 3672)
# Title Authors PMID Year
1
Effects of the administration of oxytocin or carbetocin to dairy cows at parturition on their subsequent fertility. 61 54
19933542 2009
2
WITHDRAWN: Oxytocin for prelabour rupture of membranes at or near term. 61 54
17636608 2007
3
Oxytocin for prelabour rupture of membranes at or near term. 61 54
10796159 2000
4
Premature rupture of membranes at term: a meta-analysis of three management schemes. 61 54
9170488 1997
5
Clinical amnionitis and endometritis in patients with premature rupture of membranes: endocervical prostaglandin E2 gel versus oxytocin for induction of labor. 54 61
8841214 1996
6
Oxytocin enhances clearance of radiocolloid from the uterine lumen of reproductively normal mares and mares susceptible to endometritis. 61 54
8575394 1994
7
Investigations into the use of exogenous oxytocin for promoting uterine drainage in mares susceptible to endometritis. 61 54
1897091 1991
8
Decreasing of S100A4 in bovine endometritis in vivo and in vitro. 61
32442742 2020
9
Variation of diagnostic criteria in women with chronic endometritis and its effect on reproductive outcomes: A systematic review and meta-analysis. 61
32442825 2020
10
TLR2/4 promotes PGE2 production to increase tissue damage in Escherichia coli-infected bovine endometrial explants via MyD88/p38 MAPK pathway. 61
32408026 2020
11
Prevalence of endometritis diagnosed by vaginal discharge scoring or uterine cytology in dairy cows and herds. 61
32359992 2020
12
Exosome-derived uterine miR-218 isolated from cows with endometritis regulates the release of cytokines and chemokines. 61
32227590 2020
13
Associations of reproductive indices with fertility outcomes, milk yield, and survival in Holstein cows. 61
32359989 2020
14
Neutrophils, monocytes and other immune components in the equine endometrium: Friends or foes? 61
31973963 2020
15
Preventing postpartum uterine disease in dairy cattle depends on avoiding, tolerating and resisting pathogenic bacteria. 61
31973964 2020
16
Modulation of immune function in the bovine uterus peripartum. 61
31987594 2020
17
Adipokines as biomarkers of postpartum subclinical endometritis in dairy cows. 61
32567551 2020
18
Maternal and neonatal outcomes following a prolonged second stage of labor: A meta-analysis of observational studies. 61
32570187 2020
19
Myometrial Pseudoaneurysm and Myelosuppression Following Conservative Management of Cesarean Scar Ectopic Pregnancy. 61
31864915 2020
20
Uterine body placenta accreta spectrum: A detailed literature review. 61
32452401 2020
21
The Influence of Academic Hospitalists on Labor and Delivery Outcomes. 61
32516793 2020
22
Relationship of chronic endometritis with chronic deciduitis in cases of miscarriage. 61
32487112 2020
23
Therapeutic potential of a designed CSαβ peptide ID13 in Staphylococcus aureus-induced endometritis of mice. 61
32506158 2020
24
Perception of farmers about endometritis prevention and control measures for zero-grazed dairy cows on smallholder farms in Rwanda. 61
32503530 2020
25
Association between chronic endometritis and uterine natural killer cell density in women with recurrent miscarriage: clinical implications. 61
32189458 2020
26
Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy. 61
32505843 2020
27
In women with chronic or subclinical endometritis is hysteroscopy suitable for setting the diagnosis? A systematic review. 61
32578286 2020
28
Streptococcus uberis strains originating from bovine uteri provoke upregulation of pro-inflammatory factors mRNA expression of endometrial epithelial cells in vitro. 61
32456828 2020
29
Routine uterine culture swab during cesarean section and its clinical correlations: A retrospective comparative study. 61
32348949 2020
30
LPS-treatment of bovine endometrial epithelial cells causes differential DNA methylation of genes associated with inflammation and endometrial function. 61
32493210 2020
31
Pregnancy and delivery in women with a high risk of infection in pregnancy. 61
32576052 2020
32
Genital TB screening at an academic fertility center in the US. 61
32497612 2020
33
Determining diagnostic criteria and cause of recurrent implantation failure. 61
32251092 2020
34
Contemporaneous management of ampicillin infusions in the outpatient setting through the use of therapeutic drug monitoring. 61
32325205 2020
35
[Placenta accreta spectrum disorder: Management and morbidity in a French type-3 maternity]. 61
32173598 2020
36
The effect of mechanical cervical dilatation during scheduled cesarean section on the blood loss: a randomized controlled trial. 61
30317902 2020
37
Can we induce labor by mechanical methods following preterm premature rupture of membranes? 61
32422363 2020
38
Outcomes associated with trial of labor after cesarean in women with one versus two prior cesarean deliveries after a change in clinical practice guidelines in an academic hospital. 61
30185092 2020
39
Combination Foley catheter and prostaglandins or Foley and oxytocin for cervical ripening: a network meta-analysis. 61
32387325 2020
40
Is Group B Streptococcus Colonization Associated with Maternal Peripartum Infection in an Era of Routine Prophylaxis? 61
32446262 2020
41
Experimentally induced endometritis impairs the developmental capacity of bovine oocytes. 61
32401311 2020
42
Endometritis Changes the Neurochemical Characteristics of the Caudal Mesenteric Ganglion Neurons Supplying the Gilt Uterus. 61
32443879 2020
43
[Establishment and evaluation of multiplex PCR for detection of main pathogenic bacteria of endometritis in Tibetan sheep]. 61
32567274 2020
44
Invasive Group A streptococcal postpartum endometritis associated with multi-organ infarctions: an uncommon case presentation and literature review. 61
32379557 2020
45
Isolation and characteristics of multi-drug resistant Streptococcus porcinus from the vaginal secretions of sow with endometritis. 61
32434590 2020
46
Intrauterine therapy with ozone reduces subclinical endometritis and improves reproductive performance in postpartum dairy cows managed in pasture-based systems. 61
32445159 2020
47
Study To Reduce Infection Prior to Elective Cesarean Deliveries (STRIPES): A randomized clinical trial of chlorhexidine. 61
32407786 2020
48
Comparison of maternal and fetal complications in pregnant women with breech presentation undergoing spontaneous or induced vaginal delivery, or cesarean delivery. 61
32416886 2020
49
Ovary and ovarian bursa in dromedary camels: Clinical relevance of the topographical features. 61
32030811 2020
50
A Gap in Care? Postpartum Women Presenting to the Emergency Room and Getting Readmitted. 61
32473598 2020

Variations for Endometritis

Expression for Endometritis

Search GEO for disease gene expression data for Endometritis.

Pathways for Endometritis

Pathways related to Endometritis according to GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.06 TNF TLR4 TLR2 SIGLEC5 IL6 IL1B
2
Show member pathways
13.45 TNF TLR4 TLR2 IL6 IL1B CXCL8
3
Show member pathways
13.38 TNF IL6 IL1B HLA-DQB1 HLA-DQA1 CXCL8
4
Show member pathways
13.08 TNF TLR4 TLR2 IL6 IL1B CXCL8
5
Show member pathways
12.97 TNF TLR4 TLR2 IL6 IL1B CXCL8
6
Show member pathways
12.9 TNF IL6 IL1B HLA-DQB1 HLA-DQA1 CXCL8
7 12.85 TNF TLR2 IL6 IL1B HLA-DQB1 HLA-DQA1
8
Show member pathways
12.77 TNF TLR4 TLR2 IL6 IL1B CXCL8
9
Show member pathways
12.74 TNF TLR4 TLR2 IL6 IL1B HLA-DQB1
10
Show member pathways
12.73 TNF TLR4 TLR2 IL6 IL1B
11
Show member pathways
12.64 TNF TLR4 TLR2 IL6 IL1B
12
Show member pathways
12.59 TNF TLR4 TLR2 IL6 IL1B HLA-DQB1
13 12.41 TNF TLR4 IL1B CXCL8
14
Show member pathways
12.39 TNF IL6 CXCL8 CXCL13 CXCL1
15
Show member pathways
12.38 TNF TLR4 SDC1 IL6 IL1B CXCL8
16
Show member pathways
12.37 TNF TLR2 IL6 IL1B CXCL8 CXCL1
17 12.36 TNF IL6 HLA-DQB1 HLA-DQA1
18 12.36 TNF TLR4 TLR2 SDC1 ESR1
19 12.34 TNF TLR4 TLR2 IL6 IL1B CXCL8
20 12.32 TNF TLR4 IL6 IL1B CXCL8
21
Show member pathways
12.31 TNF TLR4 TLR2 IL6 CXCL8
22
Show member pathways
12.28 TNF TLR4 TLR2 IL1B HLA-DQB1 HLA-DQA1
23
Show member pathways
12.25 TNF TLR4 IL1B GLUD1
24 12.23 TNF TLR4 TLR2 IL6
25 12.23 TNF TLR4 IL6 IL1B CXCL8 CXCL1
26 12.22 TNF IL6 IL1B CXCL8
27 12.18 TLR4 TLR2 HLA-DQB1 HLA-DQA1
28
Show member pathways
12.15 TNF TLR4 TLR2 IL6 IL1B CXCL8
29 12.12 TNF TLR4 TLR2 IL6 IL1B HLA-DQB1
30 12.08 TNF TLR4 IL6 IL1B CXCL8
31 12.04 TNF IL6 IL1B CXCL8
32 12.03 TNF IL6 IL1B CXCL1
33
Show member pathways
12.01 TNF TLR4 TLR2 IL6 IL1B
34 12 IL6 IL1B CXCL8 CXCL1
35 11.99 TNF TLR4 IL1B CXCL8 CXCL1
36 11.97 TNF IL6 IL1B CXCL8
37 11.96 TNF IL6 IL1B HLA-DQB1 HLA-DQA1
38
Show member pathways
11.94 TLR4 IL6 CXCL8 CXCL1
39
Show member pathways
11.93 TLR4 TLR2 IL6 IL1B
40 11.92 TNF TLR4 IL6 IL1B CXCL8 CXCL1
41 11.81 TNF TLR4 TLR2 IL6 IL1B CXCL8
42 11.77 TNF IL6 IL1B
43 11.76 TNF TLR4 IL6 IL1B CXCL8
44
Show member pathways
11.73 TNF IL6 IL1B CXCL8
45 11.72 TNF IL6 IL1B CXCL8
46 11.59 TNF TLR4 TLR2 IL1B
47 11.57 TNF IL6 HP
48 11.53 TNF IL6 IL1B
49 11.49 TNF IL6 IL1B CXCL8 CXCL1
50 11.46 TNF TLR4 TLR2 IL6 IL1B CXCL8

GO Terms for Endometritis

Cellular components related to Endometritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.32 TNF OXT MIRLET7C MIR27A IL6 IL1B

Biological processes related to Endometritis according to GeneCards Suite gene sharing:

(show all 43)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.29 TLR4 TLR2 PGR OXT IL6 IL1B
2 positive regulation of transcription by RNA polymerase II GO:0045944 10.22 TNF TLR4 TLR2 PGR MIRLET7C IL6
3 positive regulation of gene expression GO:0010628 10.08 TNF TLR4 TLR2 IL6 IL1B
4 negative regulation of cell proliferation GO:0008285 10.06 TLR2 IL6 IL1B CXCL8 CXCL1
5 positive regulation of DNA-binding transcription factor activity GO:0051091 9.93 TNF IL6 IL1B ESR1
6 cytokine-mediated signaling pathway GO:0019221 9.93 TNF SDC1 IL6 IL1B CXCL8 CXCL1
7 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.91 TNF TLR4 TLR2 IL6 IL1B
8 defense response GO:0006952 9.89 TNF HP CXCL8 CXCL13 CXCL1
9 positive regulation of inflammatory response GO:0050729 9.88 TNF TLR4 TLR2 IL1B
10 positive regulation of JNK cascade GO:0046330 9.87 TNF TLR4 IL1B
11 neutrophil chemotaxis GO:0030593 9.86 IL1B CXCL8 CXCL13 CXCL1
12 chemokine-mediated signaling pathway GO:0070098 9.85 CXCL8 CXCL13 CXCL1
13 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.85 CXCL8 CXCL13 CXCL1
14 response to glucocorticoid GO:0051384 9.84 TNF SDC1 OXT IL6
15 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.83 TNF TLR4 TLR2 IL1B
16 positive regulation of interferon-gamma production GO:0032729 9.82 TNF TLR4 IL1B
17 positive regulation of nitric oxide biosynthetic process GO:0045429 9.82 TNF TLR4 IL1B
18 negative regulation of neurogenesis GO:0050768 9.79 TNF IL6 IL1B
19 leukocyte chemotaxis GO:0030595 9.77 CXCL8 CXCL13 CXCL1
20 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.76 TNF TLR4 IL6
21 positive regulation of glial cell proliferation GO:0060252 9.74 TNF IL6 IL1B
22 positive regulation of interleukin-6 secretion GO:2000778 9.73 TNF TLR4 TLR2 IL1B
23 positive regulation of interleukin-8 secretion GO:2000484 9.72 TNF TLR4 TLR2
24 lipopolysaccharide-mediated signaling pathway GO:0031663 9.71 TNF TLR4 TLR2 IL1B
25 cellular response to lipopolysaccharide GO:0071222 9.7 TNF TLR4 IL6 IL1B CXCL8 CXCL13
26 response to molecule of bacterial origin GO:0002237 9.69 TLR2 CXCL8
27 negative regulation of production of miRNAs involved in gene silencing by miRNA GO:1903799 9.68 TNF ESR1
28 cellular response to lipoteichoic acid GO:0071223 9.68 TLR4 TLR2
29 negative regulation of lipid storage GO:0010888 9.68 TNF IL6
30 positive regulation of interleukin-8 production GO:0032757 9.67 TNF TLR4 TLR2 IL1B
31 regulation of establishment of endothelial barrier GO:1903140 9.66 TNF IL1B
32 negative regulation of interleukin-1-mediated signaling pathway GO:2000660 9.66 MIR27A IL6
33 positive regulation of prostaglandin secretion GO:0032308 9.65 OXT IL1B
34 positive regulation of fever generation GO:0031622 9.65 TNF IL1B
35 positive regulation of neuroinflammatory response GO:0150078 9.65 TNF IL6 IL1B
36 positive regulation of interleukin-6 production GO:0032755 9.65 TNF TLR4 TLR2 IL6 IL1B
37 sequestering of triglyceride GO:0030730 9.64 TNF IL1B
38 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.63 TNF IL1B
39 positive regulation of chemokine production GO:0032722 9.62 TNF TLR4 TLR2 IL6
40 positive regulation of matrix metallopeptidase secretion GO:1904466 9.61 TLR4 TLR2
41 positive regulation of cellular response to macrophage colony-stimulating factor stimulus GO:1903974 9.61 TLR4 TLR2
42 inflammatory response GO:0006954 9.61 TNF TLR4 TLR2 SDC1 IL6 IL1B
43 immune response GO:0006955 9.32 TNF TLR4 TLR2 IL6 IL1B HLA-DQB1

Molecular functions related to Endometritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.76 TNF TLR4 TLR2 SDC1 PGR LACTB
2 chemokine activity GO:0008009 9.5 CXCL8 CXCL13 CXCL1
3 MHC class II receptor activity GO:0032395 9.37 HLA-DQB1 HLA-DQA1
4 lipopolysaccharide receptor activity GO:0001875 9.26 TLR4 TLR2
5 CXCR chemokine receptor binding GO:0045236 9.13 CXCL8 CXCL13 CXCL1
6 cytokine activity GO:0005125 9.1 TNF IL6 IL1B CXCL8 CXCL13 CXCL1

Sources for Endometritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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