MCID: END047
MIFTS: 54

Endophthalmitis

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Endophthalmitis

MalaCards integrated aliases for Endophthalmitis:

Name: Endophthalmitis 12 60 56 45 15 74

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 60  
Rare eye diseases


External Ids:

Disease Ontology 12 DOID:4692
MeSH 45 D009877
NCIt 51 C34586
SNOMED-CT 69 1847009 82255004
ICD10 34 H45.1
MESH via Orphanet 46 D009877
ICD10 via Orphanet 35 H44.0 H44.1
UMLS via Orphanet 75 C0014236
Orphanet 60 ORPHA199323
UMLS 74 C0014236

Summaries for Endophthalmitis

Disease Ontology : 12 A globe disease that is characterized by inflammation of the inside of the eye.

MalaCards based summary : Endophthalmitis is related to acute endophthalmitis and purulent endophthalmitis, and has symptoms including redness or discharge of eye An important gene associated with Endophthalmitis is CARD9 (Caspase Recruitment Domain Family Member 9), and among its related pathways/superpathways are Tuberculosis and Colorectal Cancer Metastasis. The drugs Cefazolin and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include eye, liver and endothelial, and related phenotypes are hematopoietic system and cardiovascular system

Wikipedia : 77 Endophthalmitis is an inflammation of the interior of the eye. It is a possible complication of all... more...

Related Diseases for Endophthalmitis

Diseases in the Endophthalmitis family:

Chronic Endophthalmitis Acute Endophthalmitis

Diseases related to Endophthalmitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 299)
# Related Disease Score Top Affiliating Genes
1 acute endophthalmitis 34.1 PRF1 VEGFA
2 purulent endophthalmitis 33.5 MRAP PRF1 VEGFA
3 corneal abscess 30.1 DEFB1 PLG
4 vitreous detachment 30.1 PLG VEGFA
5 conjunctivitis 29.7 ICAM1 IL6 PLG
6 macular dystrophy, dominant cystoid 29.6 MRAP VEGFA
7 bacteriuria 29.6 IL6 PRF1
8 retinal artery occlusion 29.3 IL6 VEGFA
9 macular retinal edema 28.7 ICAM1 IL6 MRAP VEGFA
10 chronic endophthalmitis 12.4
11 phacoanaphylactic uveitis 11.8
12 fungal keratitis 11.5
13 cataract 11.0
14 sympathetic ophthalmia 10.7
15 keratitis, hereditary 10.5
16 endocarditis 10.4
17 uveitis 10.3
18 meningitis 10.3
19 heterophyiasis 10.3 ICAM1 SELE
20 lymphocytic vasculitis 10.3 ICAM1 SELE
21 retinal detachment 10.3
22 mooren's ulcer 10.3 ICAM1 SELE
23 hymenolepiasis 10.3 ICAM1 SELE
24 macrophage activation syndrome 10.3 HMGB1 PRF1
25 plummer's disease 10.3 ICAM1 SELE
26 subendocardial myocardial infarction 10.3 ICAM1 SELE
27 actinic prurigo 10.3 ICAM1 SELE
28 rheumatoid vasculitis 10.3 ICAM1 SELE
29 osteonecrosis of the jaw 10.3 DEFB1 VEGFA
30 strabismus 10.3
31 mechanical strabismus 10.3
32 stenotrophomonas maltophilia infection 10.3
33 hydrocele 10.2 ICAM1 VEGFA
34 hypopyon 10.2
35 leukocyte adhesion deficiency, type i 10.2 ICAM1 SELE
36 cellulitis 10.2
37 chronic myocardial ischemia 10.2 PLG VEGFA
38 leukemia 10.2
39 scleritis 10.2
40 vulvovaginal candidiasis 10.2 DEFB1 TLR2
41 primary systemic mycosis 10.2 CARD9 TLR2
42 orbital cellulitis 10.2
43 retinal vascular occlusion 10.2 PLG VEGFA
44 candidiasis 10.1
45 candida glabrata 10.1
46 vitreous disease 10.1 PLG VEGFA
47 osgood-schlatter's disease 10.1 MRAP PRF1
48 retinitis 10.1
49 pneumonia 10.1
50 leukostasis 10.1 ICAM1 SELE VEGFA

Graphical network of the top 20 diseases related to Endophthalmitis:



Diseases related to Endophthalmitis

Symptoms & Phenotypes for Endophthalmitis

UMLS symptoms related to Endophthalmitis:


redness or discharge of eye

MGI Mouse Phenotypes related to Endophthalmitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.97 CARD9 GON4L ICAM1 IL6 PLG PRF1
2 cardiovascular system MP:0005385 9.91 ICAM1 IL6 PLG PRF1 SELE TLR2
3 immune system MP:0005387 9.91 CARD9 GON4L ICAM1 IL6 PLG PRF1
4 integument MP:0010771 9.7 ICAM1 IL6 PLG PRF1 SELE TLR2
5 liver/biliary system MP:0005370 9.43 IL6 PLG PRF1 SELE TLR2 VEGFA
6 neoplasm MP:0002006 9.17 GON4L ICAM1 IL6 PLG PRF1 TLR2

Drugs & Therapeutics for Endophthalmitis

Drugs for Endophthalmitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 205)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cefazolin Approved Phase 4,Not Applicable 25953-19-9 33255 656510
2
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
3
Moxifloxacin Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 354812-41-2, 151096-09-2 152946
4
Ethinyl Estradiol Approved Phase 4,Phase 2,Phase 3,Not Applicable 57-63-6 5991
5
Polyestradiol phosphate Approved Phase 4,Phase 2,Phase 3,Not Applicable 28014-46-2
6
Norgestimate Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 35189-28-7 6540478
7
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-28-2 5757
8
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 302-25-0
9
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 124-94-7 31307
10
Prednisolone Approved, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 50-24-8 5755
11
Methylprednisolone Approved, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 83-43-2 6741
12
Methylprednisolone hemisuccinate Approved Phase 4,Phase 1,Phase 2,Not Applicable 2921-57-5
13
Ranibizumab Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 347396-82-1 459903
14
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 50-02-2 5743
15
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 1177-87-3
16
Bevacizumab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 216974-75-3
17
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 22916-47-8 4189
18
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
19
Iodine Approved, Investigational Phase 4,Phase 1,Not Applicable 7553-56-2 807
20
Povidone Approved Phase 4,Phase 1,Not Applicable 9003-39-8
21
Povidone-iodine Approved Phase 4,Phase 3,Phase 1,Not Applicable 25655-41-8
22
Ofloxacin Approved Phase 4,Phase 3,Not Applicable 82419-36-1 4583
23
Levofloxacin Approved, Investigational Phase 4,Phase 3,Not Applicable 100986-85-4 149096
24
Prednisolone hemisuccinate Experimental Phase 4,Phase 1,Phase 2,Not Applicable 2920-86-7
25 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
26 Cephalosporins Phase 4
27 Diuretics, Potassium Sparing Phase 4,Not Applicable
28 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
29 Anesthetics Phase 4,Phase 3,Not Applicable
30 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Not Applicable
31 Anti-Arrhythmia Agents Phase 4,Not Applicable
32 Sodium Channel Blockers Phase 4,Not Applicable
33 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
34 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Anesthetics, Local Phase 4,Not Applicable
36 Central Nervous System Depressants Phase 4,Not Applicable
37 Antitubercular Agents Phase 4,Phase 3,Not Applicable
38 Norgestimate, ethinyl estradiol drug combination Phase 4,Phase 2,Phase 3,Not Applicable
39 Ophthalmic Solutions Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
40 Contraceptives, Oral Phase 4,Phase 2,Phase 3,Not Applicable
41 Contraceptives, Oral, Combined Phase 4,Phase 2,Phase 3,Not Applicable
42 Estradiol 3-benzoate Phase 4,Phase 2,Phase 3,Not Applicable
43 Contraceptive Agents Phase 4,Phase 2,Phase 3,Not Applicable
44 Estradiol 17 beta-cypionate Phase 4,Phase 2,Phase 3,Not Applicable
45 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
46 Neuroprotective Agents Phase 4,Not Applicable
47 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
48 Immunologic Factors Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
49 Immunosuppressive Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
50 Triamcinolone hexacetonide Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 149)
# Name Status NCT ID Phase Drugs
1 Cefazolin-Lidocaine Combination Solution to Reduce Antibiotic Pain Unknown status NCT02324166 Phase 4 Cefazolin;Lidocaine
2 Dosage Study for Vigamox Eye Drops Prior to Intravitreal Injections Unknown status NCT00690313 Phase 4 Vigamox
3 IntraVitreal Triamcinolone Acetonide: Preventing Raised Eye-pressure by Tracking Elevations After Topical Steroids Unknown status NCT00744666 Phase 4 Prednisolone 1% topical eye drops
4 Effects of Ranibizumab to Delay or Regression Non-proliferative Diabetic Retinopathy(NPDR) With DME Assessed by Microaneurysm Changes: A Pilot Study Unknown status NCT02834663 Phase 4 Lucentis
5 A Two Chemoprophylaxis Approaches After Phacoemulsification Surgery Completed NCT03634852 Phase 4 Moxifloxacin hydrochloride 0.5% eye drops;Dexamethasone 0.1% eye drops;Intracameral Moxifloxacin 0.1%;Subconjunctival Triamcinolone acetonide 4 mg /0.4 ml
6 Prophylaxis of Acute Post-Traumatic Bacterial Endophthalmitis Completed NCT00398658 Phase 4 gentamycin and clindamycin
7 Povidone-iodine Antisepsis for Strabismus Surgery Completed NCT00461656 Phase 4 Preoperative conjunctival irrigation with 5% or 1.25% PI
8 Evaluation of the Effect of Intravitreal Injections of Anti-VEGF on Macular Perfusion in Diabetic Patients Using OCTA Completed NCT03246152 Phase 4 Bevacizumab
9 Comparative Study of Ologen Collagen Matrix Versus Mitomycin-C in Glaucoma Filtering Surgery Completed NCT01440751 Phase 4 Use of Mitomycin-C (MMC) in trabeculectomy
10 Comparative Efficacy of Different Regimens of PVPI 5% Eye Drops Instillation in Reducing Conjunctival Bacterial Flora Completed NCT01739920 Phase 4
11 Effectiveness of Topical 0.5% Levofloxacin to Reduce the Conjunctival Bacterial Flora Before Intraocular Surgery Completed NCT00491049 Phase 4 0.5% levofloxacin eye drops
12 Aurolab Hydrophobic Foldable Intraocular Lens Study Completed NCT00449267 Phase 4
13 Intravitreal Aflibercept Injection for the Treatment of Submacular Vascularized Pigment Epithelial Detachment Completed NCT01722656 Phase 4 Aflibercept
14 Evaluation of Macular Changes After Intracameral Moxifloxacin for Prevention of Endophthalmitis Recruiting NCT03363295 Phase 4 Moxifloxacin Injection
15 Influence of Diabetes Control on Treatment of Diabetic Macular Edema With Ranibizumab Recruiting NCT02665689 Phase 4 ranibizumab
16 Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients Withdrawn NCT00304772 Phase 4 Fluconazole;Micafungin
17 The Safety and Efficacy of a Tumor Necrosis Factor Receptor Fusion Protein on Uveitis Associated With Juvenile Rheumatoid Arthritis Unknown status NCT00012506 Phase 3 TNFR:Fc
18 Double-dose Ranibizumab for Polypoidal Choroidal Vasculopathy Unknown status NCT02769169 Phase 2, Phase 3 Lucentis® (Raibizumab) double-dose;Lucentis® (Raibizumab) regular-dose
19 Efficacy and Tolerance Comparison Between Subconjunctival Injection of Triamcinolone and Intravitreal Implant of Dexamethasone for the Treatment of Inflammatory Macular Edema Unknown status NCT02556424 Phase 3 Dexamethasone;Triamcinolone
20 Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis Completed NCT01768078 Phase 3
21 Endophthalmitis Vitrectomy Study (EVS) Completed NCT00000130 Phase 3 Intravitreal Antibiotics
22 Clinical Trial of Eye Prophylaxis in the Newborn Completed NCT00000120 Phase 3 Erythromycin Ointment;Silver Nitrate Drops
23 Retaane® in Age-Related Macular Degeneration Completed NCT00569569 Phase 2, Phase 3 juxtascleral depot injection of Retaane
24 Systemic Avastin Therapy in Age-Related Macular Degeneration Completed NCT00531024 Phase 2, Phase 3 Bevacizumab;Sodium Chloride
25 Effect of Intravitreal Ranibizumab Injection With Retinal Vein Occlusion (RVO) Completed NCT00942864 Phase 3 ranibizumab
26 PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial Completed NCT02374060 Phase 3 Periocular triamcinolone 40 mg;Intravitreal triamcinolone 4 mg;Dexamethasone intravitreal implant
27 PRevention of Macular EDema After Cataract Surgery Completed NCT01774474 Phase 3 Bromfenac;Dexamethasone;Bevacizumab;Triamcinolone Acetonide
28 Levo-Dexa vs. Tobra+Dexa for Prevention and Treatment of Inflammation and Prevention of Infection in Cataract Surgery Recruiting NCT03739528 Phase 3 Levofloxacin + dexamethasone followed by dexamethasone;Tobramycin + Dexamethasone
29 Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial Recruiting NCT02623426 Phase 3 Dexamethasone intravitreal implant 0.7 mg;Intravitreal Methotrexate 400 µg;Intravitreal Ranibizumab 0.5 mg
30 A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behcet's Disease Active, not recruiting NCT02307513 Phase 3 Apremilast (CC-10004);Placebo
31 Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery Not yet recruiting NCT03244072 Phase 2, Phase 3 Moxifloxacin;Placebo
32 Intracameral Antibiotic Safety Study Not yet recruiting NCT02590523 Phase 3 Vancomycin;Moxifloxacin;Placebo
33 Evaluation of Efficacy and Safety of Intracameral Moxifloxacin for Prevention of Postcataract Endophthalmitis. Terminated NCT02770729 Phase 3 Moxifloxacin;No injection of moxifloxacin
34 Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa Terminated NCT01103063 Phase 3 Azithromycin plus chloroquine;sulfadoxine-pyrimethamine
35 A Study of the Safety, Tolerability, and Efficacy of IVT Pre-op 0.3mg Pegaptanib Sodium Versus Sham, for Management of Tractional Retinal Detachment and Vitreous Hemorrhage With Proliferative Diabetic Retinopathy Withdrawn NCT01589718 Phase 3 Macugen;Sham
36 The Effect of Intravitral Injection of Triamcinolone Combined With Cataract Surgery (Phacoemulsification) on Diabetic Macular Edema and Diabetic Retinopathy Unknown status NCT00849537 Phase 1, Phase 2 Triamcinolone
37 Endolaserless Vitrectomy With Intravitreal IAI for PDR-Related VH Unknown status NCT02976012 Phase 1, Phase 2 Aflibercept
38 Safety Study of 2.0mg Lucentis to Treat Polypoidal Choroidal Vasculopathy Unknown status NCT01469156 Phase 1, Phase 2 ranibizumab 0.5 or 2.0 mg/0.05 cc
39 Ranibizumab For Persistent Diabetic Macular Edema After Bevacizumab Unknown status NCT01845844 Phase 1, Phase 2 Ranibizumab 0.3mg/0.05cc
40 Safety Study of Conventional Versus Micropulse Transscleral Cyclophotocoagulation in Treating End-Stage Glaucoma Unknown status NCT00349414 Phase 1, Phase 2
41 Intracameral Moxifloxacin for Prevention of Postcataract Endophthalmitis Completed NCT02595359 Phase 2 Moxifloxacin
42 TNRF:Fc to Treat Eye Inflammation in Juvenile Rheumatoid Arthritis Completed NCT00001862 Phase 2 Enbrel
43 Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients Completed NCT00001311 Phase 2
44 Combination Ranibizumab and Bromfenac for Neovascular Age-related Macular Degeneration Completed NCT00805233 Phase 2 combination ranibizumab + bromfenac;ranibizumab injection alone
45 Ranibizumab and Reduced Fluence PDT for AMD Completed NCT00527475 Phase 2 ranibizumab;verteporfin
46 20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD) Completed NCT01175395 Phase 1, Phase 2 IBI-20089/Lucentis
47 HAT in Eye Complications of Behcet's Disease Completed NCT00001865 Phase 2 Daclizumab
48 Daclizumab to Treat Non-Infectious Sight-Threatening Uveitis Completed NCT00070759 Phase 2 Daclizumab
49 Daclizumab Injections to Treat Non-Infectious Sight-Threatening Uveitis Completed NCT00043667 Phase 2 Daclizumab
50 Trabeculectomy With Ologen Collagen Implant vs Trabeculectomy With Provisc in Steroid Induced Glaucoma Completed NCT01912638 Phase 1, Phase 2 Provisc

Search NIH Clinical Center for Endophthalmitis

Cochrane evidence based reviews: endophthalmitis

Genetic Tests for Endophthalmitis

Anatomical Context for Endophthalmitis

MalaCards organs/tissues related to Endophthalmitis:

42
Eye, Liver, Endothelial, Prostate, Testes, Myeloid, Kidney

Publications for Endophthalmitis

Articles related to Endophthalmitis:

(show top 50) (show all 3095)
# Title Authors Year
1
Physical Incompatibility between Vancomycin and Viscoelastic Mimicking Acute Endophthalmitis: The First Report. ( 30863651 )
2019
2
ACUTE MYOCARDITIS WITH CARDIOGENIC SHOCK AND MULTIPLE ORGAN FAILURE, FOLLOWED BY BILATERAL PANUVEITIS MASQUERADING AS ENDOGENOUS ENDOPHTHALMITIS, DUE TO TOXOPLASMA GONDII IN AN IMMUNOCOMPETENT PATIENT. ( 30664080 )
2019
3
Juvenile idiopathic arthritis-related uveitis mimicking endophthalmitis. ( 30959168 )
2019
4
Endophthalmitis after Cataract Surgery in Korea: A Nationwide Study Evaluating Incidence and Risk Factors in a Korean Population. ( 31016909 )
2019
5
Risk factors for endophthalmitis after cataract surgery in diabetic patients: a case control study. ( 30918810 )
2019
6
Dual drug delivery from intraocular lens material for prophylaxis of endophthalmitis in cataract surgery. ( 30630077 )
2019
7
Endophthalmitis following cataract surgery and intracameral antibiotic: Moxifloxacin resistant Staphylococcus epidermidis. ( 30662972 )
2019
8
Incidence of acute-onset endophthalmitis after separate bilateral cataract surgeries less than 5 days apart. ( 30683069 )
2019
9
Safety and efficacy of intracameral moxifloxacin for prevention of post-cataract endophthalmitis: Randomized controlled clinical trial. ( 30691922 )
2019
10
Endophthalmitis Incidence of Cancer Patients After Cataract Surgery: A Nationwide Matched Cohort Study in Taiwan. ( 30529565 )
2019
11
Is combined cataract surgery associated with acute postoperative endophthalmitis? A nationwide study from 2005 to 2014. ( 29925513 )
2019
12
Bacteriology and cefuroxime resistance in endophthalmitis following cataract surgery before and after the introduction of prophylactic intracameral cefuroxime: a retrospective single-centre study. ( 29432821 )
2019
13
Multimodal imaging including adaptive optics: A case of a candida chorioretinitis progressing to endogenous endophthalmitis. ( 30824310 )
2019
14
Endogenous Endophthalmitis Caused by Infective Endocarditis in East Asia. ( 31014693 )
2019
15
Group C Streptococcus dysgalactiae subsp.equisimilis (SDSE) Endocarditis with Endogenous Endophthalmitis and Aortic Root Abscess. ( 30899671 )
2019
16
The Early Diagnosis of Endophthalmitis Due to Group B Streptococcus Infective Endocarditis and Its Clinical Course: A Case Report and Literature Review. ( 30626848 )
2019
17
Culture-Proven Endophthalmitis After Intravitreal Injection: A 10-Year Analysis. ( 30640393 )
2019
18
A Case Report of Endogenous Endophthalmitis in the Setting of Nocardia kroppenstedtii Infection. ( 30640397 )
2019
19
Postoperative Mycobacteroides abscessus subsp. abscessus endophthalmitis: Clinical analysis of 12 clustered adults and a proposed therapeutic algorithm. ( 30661953 )
2019
20
Early Pars Plana Vitrectomy for Treatment of Acute Infective Endophthalmitis. ( 30666852 )
2019
21
Post-Traumatic Endophthalmitis due to Acinetobacter radioresistens: Virulence Potential of Commensal Bacteria. ( 30674268 )
2019
22
ENTEROCOCCUS ENDOPHTHALMITIS: Clinical Settings, Antimicrobial Susceptibility, and Management Outcomes. ( 30681640 )
2019
23
New insights into culture negative endophthalmitis by unbiased next generation sequencing. ( 30696908 )
2019
24
Prognostic Factors and Visual Outcomes of Pyogenic Liver Abscess-Related Endogenous Klebsiella pneumoniae Endophthalmitis: A 20-year retrospective review. ( 30705320 )
2019
25
Mycoplasma pneumoniae endophthalmitis in a Cuban pediatric patient. ( 30728981 )
2019
26
Absence of Posterior Vitreous Detachment Is a Risk Factor of Severe Bleb-Related Endophthalmitis. ( 30755799 )
2019
27
Impact of antibiotic resistance of pathogens and early vitrectomy on the prognosis of infectious endophthalmitis: a 10-year retrospective study. ( 30761407 )
2019
28
Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics. ( 30771529 )
2019
29
Endogenous endophthalmitis caused by Streptococcus agalactiae: An ophthalmologic emergency. ( 30775242 )
2019
30
Staphylococcus lugdunensis endophthalmitis following dexamethasone intravitreal implant. ( 30777977 )
2019
31
Commentary: Endophthalmitis following intravitreal injection of dexamethasone implant. ( 30777978 )
2019
32
Intravitreal Injection of 1.25% Povidone Iodine Followed by Vitrectomy Using 0.025% Povidone Iodine Irrigation for Treating Endophthalmitis. ( 30783556 )
2019
33
Endoscopic vitrectomy in endophthalmitis: initial experience of 33 cases at a tertiary eye care center. ( 30787589 )
2019
34
Unilateral endogenous Candida endophthalmitis after extracorporeal shock wave lithotripsy for a renal stone in an immunocompetent woman: a case report. ( 30788635 )
2019
35
Bleb-associated endophthalmitis: proportion, presentation, management and outcomes in Victoria, Australia. ( 30788894 )
2019
36
Trends in microbiological spectrum of endophthalmitis at a single tertiary care ophthalmic hospital in India: a review of 25 years. ( 30792523 )
2019
37
Culture-Proven Candida Albicans Endogenous Endophthalmitis in a Patient with Onychomycosis. ( 30794483 )
2019
38
Klebsiella Pneumoniae Endogenous Endophthalmitis Mimicking a Choroidal Neovascular Membrane with Subretinal Hemorrhage. ( 30806565 )
2019
39
Recurrent endophthalmitis caused by intraocular eyelashes. ( 30809495 )
2019
40
Intravitreal Injections of Voriconazole for Candida Endophthalmitis: A Case Series. ( 30810429 )
2019
41
Pantoe Agglomerans Endophthalmitis after Phaco Surgery: The First Case in Literature. ( 30811268 )
2019
42
Endophthalmitis with bilateral deafness from disseminated Streptococcus suis infection. ( 30814105 )
2019
43
Endophthalmitis in Oslo, Norway. ( 30816017 )
2019
44
Staphylococcus epidermidis Endophthalmitis Masquerading as Panuveitis After an Imperceptible Ocular Trauma ( 30829025 )
2019
45
Endophthalmitis associated with fungal keratitis and penetrating injuries in North China. ( 30832500 )
2019
46
VITRECTOMY FOR ENDOPHTHALMITIS IN EYES WITH OSTEOKERATOPROSTHESIS. ( 30845020 )
2019
47
Coagulase-negative Staphylococcus isolates causing endophthalmitis: Changing patterns of vancomycin susceptibilities. ( 30851810 )
2019
48
Bacteroides Spp. Blebitis, Keratitis, and Endophthalmitis Following Uncomplicated Trabeculectomy. ( 30855413 )
2019
49
Response to Kato et al.: Prevalence of, and risk factors for, hematogenous fungal endophthalmitis in patients with Candida bloodstream infection. ( 30859454 )
2019
50
Endophthalmitis following Suture Removal - Clinical Outcomes and Microbiological Profile. ( 30879381 )
2019

Variations for Endophthalmitis

Expression for Endophthalmitis

Search GEO for disease gene expression data for Endophthalmitis.

Pathways for Endophthalmitis

GO Terms for Endophthalmitis

Cellular components related to Endophthalmitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.35 HMGB1 ICAM1 PLG TLR2 VEGFA
2 extracellular space GO:0005615 9.17 DEFB1 HMGB1 ICAM1 IL6 PLG SELE

Biological processes related to Endophthalmitis according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.87 CARD9 DEFB1 HMGB1 TLR2
2 defense response to virus GO:0051607 9.77 CARD9 IL6 PRF1
3 response to hypoxia GO:0001666 9.72 ICAM1 TLR2 VEGFA
4 inflammatory response GO:0006954 9.71 HMGB1 IL6 SELE TLR2
5 response to lipopolysaccharide GO:0032496 9.7 ICAM1 SELE TLR2
6 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.63 ICAM1 IL6 TLR2
7 leukocyte cell-cell adhesion GO:0007159 9.58 ICAM1 SELE
8 positive regulation of interleukin-12 production GO:0032735 9.54 HMGB1 TLR2
9 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.54 ICAM1 IL6 VEGFA
10 positive regulation of innate immune response GO:0045089 9.51 CARD9 HMGB1
11 positive regulation of interleukin-10 production GO:0032733 9.49 HMGB1 TLR2
12 positive regulation of receptor internalization GO:0002092 9.48 SELE VEGFA
13 positive regulation of chemokine production GO:0032722 9.43 IL6 TLR2
14 positive regulation of tumor necrosis factor production GO:0032760 9.33 CARD9 HMGB1 TLR2
15 positive regulation of sprouting angiogenesis GO:1903672 9.27 VEGFA
16 positive regulation of interferon-beta production GO:0032728 9.26 TLR2
17 response to peptidoglycan GO:0032494 9.26 CARD9 IL6
18 defense response to Gram-positive bacterium GO:0050830 9.26 CARD9 DEFB1 IL6 TLR2
19 endothelial cell chemotaxis GO:0035767 9.02 VEGFA
20 positive regulation of interleukin-6 production GO:0032755 8.92 CARD9 HMGB1 IL6 TLR2

Molecular functions related to Endophthalmitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.33 HMGB1 IL6 VEGFA
2 identical protein binding GO:0042802 9.02 DEFB1 MRAP PRF1 TLR2 VEGFA
3 lipopolysaccharide binding GO:0001530 8.96 HMGB1 TLR2

Sources for Endophthalmitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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