Aliases & Classifications for Endosalpingiosis

MalaCards integrated aliases for Endosalpingiosis:

Name: Endosalpingiosis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11427
NCIt 49 C40121
SNOMED-CT 67 55850004
UMLS 71 C0269106

Summaries for Endosalpingiosis

Disease Ontology : 12 A female reproductive system disease characterized by the growth of fallopian tube-like epithelium outside the fallopian tube.

MalaCards based summary : Endosalpingiosis is related to chronic salpingitis and benign mesothelioma, and has symptoms including pelvic pain An important gene associated with Endosalpingiosis is PGR (Progesterone Receptor), and among its related pathways/superpathways are TCR Signaling (Qiagen) and Endometrial cancer. The drug Hormones has been mentioned in the context of this disorder. Affiliated tissues include lymph node, uterus and ovary, and related phenotypes are cellular and cardiovascular system

Wikipedia : 74 Endosalpingiosis is a condition in which fallopian tube-like epithelium is found outside the fallopian... more...

Related Diseases for Endosalpingiosis

Diseases related to Endosalpingiosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 462)
# Related Disease Score Top Affiliating Genes
1 chronic salpingitis 30.5 PAX8 OVGP1
2 benign mesothelioma 30.4 WT1 PAX8 KRT7 CALB2
3 leiomyomatosis 30.3 WT1 PGR CALB2
4 cystadenoma 29.9 PGR MUC1 KRT7 CALB2 BRCA1
5 papillary carcinoma 29.7 PGR PAX8 MUC1 KRT7 CALB2
6 squamous cell papilloma 29.7 TP53 HRAS
7 cystadenofibroma 29.7 WT1 PAX8 MUC1 KRT7 CALB2
8 myoma 29.6 TP53 PGR KRAS
9 leiomyosarcoma 29.5 WT1 TP53 PGR MUC1
10 clear cell adenocarcinoma 29.3 TP53 PAX8 PAX2 KRT7
11 papilloma 29.3 TP53 KRT7 KRAS
12 lymphangioma 29.1 TP53 KRAS HRAS
13 breast disease 29.0 TP53 PGR BRCA2 BRCA1
14 cervical adenocarcinoma 28.9 TP53 PGR KRT7 KRAS CALB2
15 endometrial adenocarcinoma 28.7 TP53 PGR MUC1 KRT7 KRAS
16 adenofibroma 28.7 WT1 TP53 PAX8 MUC1 KRT7 CALB2
17 endocervical adenocarcinoma 28.7 TP53 PGR PAX8 PAX2 MUC1 KRT7
18 signet ring cell adenocarcinoma 28.5 TP53 MUC1 KRT7 KRAS HRAS
19 cystadenocarcinoma 28.3 TP53 PGR PAX8 MUC1 KRT7 HRAS
20 adenocarcinoma 27.9 TP53 MUC1 KRT7 KRAS HRAS BRCA2
21 bladder cancer 27.7 TP53 MUC1 KRAS HRAS BRCA2 BRCA1
22 serous cystadenocarcinoma 27.1 WT1 TP53 PGR PAX8 KRT7 KRAS
23 papillary adenocarcinoma 27.1 TP53 PGR MUC1 KRT7 KRAS HRAS
24 ovarian serous cystadenocarcinoma 26.7 TP53 PGR PAX8 PAX2 MUC1 KRAS
25 ovarian cancer 26.6 WT1 TP53 PGR PAX8 MUC1 KRT7
26 endometrial cancer 26.0 WT1 TP53 PGR PAX8 MUC1 KRT7
27 florid cystic endosalpingiosis of the uterus 12.4
28 endometriosis 10.7
29 chronic tympanitis 10.5 PGR MUC1
30 breast scirrhous carcinoma 10.5 PGR MUC1
31 lipid-rich breast carcinoma 10.5 PGR MUC1
32 endometrial mucinous adenocarcinoma 10.5 PGR MUC1
33 peritoneal benign neoplasm 10.5 PGR CALB2
34 cervical serous adenocarcinoma 10.5 WT1 PGR
35 adult type testicular granulosa cell tumor 10.5 PGR CALB2
36 bartholin's gland adenoid cystic carcinoma 10.5 PGR KRT7
37 scrotum paget's disease 10.5 MUC1 KRT7
38 urethral villous adenoma 10.5 PGR KRT7
39 spindle cell thymoma 10.5 MUC1 CALB2
40 gallbladder signet ring cell adenocarcinoma 10.4 MUC1 KRT7
41 oncocytic breast carcinoma 10.4 PGR KRT7
42 biliary papillomatosis 10.4 MUC1 KRT7
43 bartholin's gland disease 10.4 PGR KRT7
44 external ear carcinoma 10.4 PGR KRT7
45 urinary bladder villous adenoma 10.4 MUC1 KRT7
46 nodular hidradenoma 10.4 MUC1 KRT7
47 seminal vesicle adenocarcinoma 10.4 PAX8 KRT7
48 benign metastasizing leiomyoma 10.4 PGR KRT7
49 transitional meningioma 10.4 PGR MUC1
50 mucinous intrahepatic cholangiocarcinoma 10.4 MUC1 KRT7

Graphical network of the top 20 diseases related to Endosalpingiosis:



Diseases related to Endosalpingiosis

Symptoms & Phenotypes for Endosalpingiosis

UMLS symptoms related to Endosalpingiosis:


pelvic pain

MGI Mouse Phenotypes related to Endosalpingiosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.11 BRCA1 BRCA2 KRAS KRT7 PAX2 PAX8
2 cardiovascular system MP:0005385 10.08 BRCA1 HRAS KRAS PAX2 PAX8 PGR
3 endocrine/exocrine gland MP:0005379 10.06 BRCA1 BRCA2 HRAS KRAS PAX2 PAX8
4 embryo MP:0005380 10.03 BRCA1 BRCA2 KRAS PAX2 PAX8 PGR
5 neoplasm MP:0002006 9.87 BRCA1 BRCA2 HRAS KRAS PGR TP53
6 limbs/digits/tail MP:0005371 9.85 BRCA1 BRCA2 KRAS PAX8 PGR TP53
7 normal MP:0002873 9.81 BRCA1 BRCA2 CALB2 HRAS KRAS PAX8
8 no phenotypic analysis MP:0003012 9.73 HRAS KRAS PAX8 PGR TP53 WT1
9 renal/urinary system MP:0005367 9.56 BRCA1 HRAS KRAS KRT7 PAX2 PAX8
10 reproductive system MP:0005389 9.28 BRCA1 BRCA2 KRAS OVGP1 PAX2 PAX8

Drugs & Therapeutics for Endosalpingiosis

Drugs for Endosalpingiosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Hormones

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Tight Vaginoscopy: a Simplified Novel Technique for a Better Vaginal Surgery Completed NCT03024242 Phase 2
2 Hysterectomy for Benign Gynaecological Conditions With or Without Tubectomy Completed NCT02281487

Search NIH Clinical Center for Endosalpingiosis

Genetic Tests for Endosalpingiosis

Anatomical Context for Endosalpingiosis

MalaCards organs/tissues related to Endosalpingiosis:

40
Lymph Node, Uterus, Ovary, Appendix, Breast, Colon, Spleen

Publications for Endosalpingiosis

Articles related to Endosalpingiosis:

(show top 50) (show all 267)
# Title Authors PMID Year
1
A Clinicopathologic Study and Descriptive Analysis of "Atypical Endosalpingiosis". 61
31033796 2020
2
Low-grade Serous Carcinoma Arising in Inguinal Nodal Endosalpingiosis: Report of 2 Cases and Literature Review. 61
31157685 2020
3
Increased association of ovarian cancer in women with histological proven endosalpingiosis. 61
32146389 2020
4
A Rare Mimic of Malignancy: Papillary Endosalpingiosis. 61
31566037 2020
5
Oncogenic BRAF and KRAS mutations in endosalpingiosis. 61
31576556 2020
6
Endosalpingiosis and other benign epithelial inclusions in breast sentinel lymph nodes. 61
31512334 2020
7
Histology of the normal ovary in premenopausal patients. 61
32172215 2020
8
Prevalence of endosalpingiosis and other benign gynecologic lesions. 61
32401810 2020
9
Concordant PET/CT and ICG positive lymph nodes in endometrial cancer: a case of mistaken identity. 61
31976060 2020
10
BRAFV600E -mutated ovarian serous borderline tumors are at relatively low risk for progression to serous carcinoma. 61
31839880 2019
11
Clinicopathologic and Molecular Features of Paired Cases of Metachronous Ovarian Serous Borderline Tumor and Subsequent Serous Carcinoma. 61
31343420 2019
12
Clinicopathologic findings in gynecologic proliferations of the appendix. 61
31430494 2019
13
Appendiceal endosalpingiosis: clinical presentation and imaging appearance of a rare condition of the appendix. 61
30367212 2019
14
Lineage tracing suggests that ovarian endosalpingiosis does not result from escape of oviductal epithelium. 61
31131879 2019
15
Endosalpingiosis of the Gallbladder: A Unique Complication of Ruptured Ectopic Pregnancy. 61
31620319 2019
16
Two rare cases of endosalpingiosis in the axillary sentinel lymph nodes: evaluation of immunohistochemical staining and one-step nucleic acid amplification (OSNA) assay in patients with breast cancer. 61
30756183 2019
17
Uterine endosalpingiosis: Case report and review of the literature. 61
31122517 2019
18
Masslike Cystic Endosalpingiosis in the Uterine Myometrium. 61
29981468 2019
19
Assessing the landscape of ovarian serous borderline tumors. 61
30659030 2019
20
Primary Peritoneal Cancer Two Decades after a Bilateral Salpingo-Oophorectomy. 61
31019818 2019
21
Intramyometrial cystic endosalpingiosis - a rare entity in gynecological pathology: A case report and brief review of the literature. 61
30706896 2019
22
Müllerianosis, Endocervicosis, and Endosalpingiosis of the Urinary Tract: A Literature Review. 61
29739266 2018
23
Florid cystic endosalpingiosis with uterine preservation and successful assisted reproductive therapy. 61
30014018 2018
24
[Intravesical salpingiosis: case report and review of the literature]. 61
28633190 2018
25
Mullerianosis of the Urinary Bladder: A Case Report. 61
29681822 2018
26
Intramural florid cystic endosalpingiosis of the uterus after menopause. 61
30509061 2018
27
Gastrointestinal: Cystic endosalpingiosis of the spleen: CT, MR, and US imaging. 61
29125210 2017
28
Reply to Rodolfo Montironi, Silvia Gasparrini, Antonio Lopez-Beltran, et al's Letter to the Editor re: Umberto Leone Roberti Maggiore, Simone Ferrero, Massimo Candiani, et al. Bladder Endometriosis: A Systematic Review of Pathogenesis, Diagnosis, Treatment, Impact on Fertility, and Risk of Malignant Transformation. Eur Urol 2017;71:790-807. Benign Müllerian Lesions in the Urinary Bladder: Endometriosis, Endocervicosis, Endosalpingiosis, and Müllerianosis. 61
28583309 2017
29
The case of the missing appendix: a case report of appendiceal intussusception at the site of colonic mullerianosis. 61
26383877 2017
30
Imaging Findings of the Unusual Presentations, Associations and Clinical Mimics of Acute Appendicitis. 61
29123444 2017
31
Polypoid endometriosis of the ovary and müllerianosis of pelvic lymph nodes mimicking an ovarian carcinoma with lymph node metastasis. 61
31149490 2017
32
Second Look of Endosalpingiosis: A Rare Entity. 61
28706372 2017
33
Diagnostic dilemma in cervical endocervicosis. 61
28791275 2017
34
Cystic endosalpingiosis of lumbar nerve root: a unique presentation. 61
27841144 2017
35
Endosalpingiosis as an obstructive entity simulating a sigma neoplasm. 61
27545415 2017
36
Mediastinal cyst of müllerian origin: evidence for developmental endosalpingiosis. 61
27913049 2017
37
Cystic Endosalpingiosis of Uterus and Ovary Found on Laparoscopy: Disease of Haze. 61
27131399 2017
38
Florid cystic endosalpingiosis associated with a retroperitoneal leiomyoma mimicking malignancy: a case report. 61
31966902 2017
39
Vaginal Endosalpingiosis Case Report: A Rare Entity Presenting as Intermenstrual Bleeding. 61
29250450 2017
40
Benign müllerian glandular inclusions in men undergoing pelvic lymph node dissection. 61
27438608 2016
41
Isolated endosalpingiosis of the appendix in an adolescent girl. 61
27671206 2016
42
Endosalpingiosis: More than just an incidental finding at the time of gynecologic surgery? 61
27261327 2016
43
Coexistent Isolated Tumor Cell Clusters of Infiltrating Lobular Carcinoma and Benign Glandular Inclusions of Müllerian (Endosalpingiosis) Type in an Axillary Sentinel Node: Case Report and Review of the Literature. 61
25203429 2016
44
Response: Cystic Endosalpingiosis or Multicystic Mesothelioma? 61
26432709 2016
45
Cystic Endosalpingiosis or Multicystic Mesothelioma? 61
26432708 2016
46
Evidence for lymphatic pathogenesis of endosalpingiosis. 61
27020212 2016
47
Florid Cystic Endosalpingiosis (Müllerianosis) in Pregnancy. 61
27668111 2016
48
Perineural space infiltration by endosalpingiosis. 61
27020213 2016
49
[Cornual pregnancy: Management and subsequent fertility]. 61
26678164 2016
50
Müllerianosis of the urinary bladder: a rare case report and review of the literature. 61
27833981 2016

Variations for Endosalpingiosis

Expression for Endosalpingiosis

Search GEO for disease gene expression data for Endosalpingiosis.

Pathways for Endosalpingiosis

Pathways related to Endosalpingiosis according to GeneCards Suite gene sharing:

(show all 22)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.67 TP53 KRAS HRAS BRCA2 BRCA1
2
Show member pathways
12.51 TP53 PAX8 KRAS HRAS BRCA2
3 12.38 TP53 PAX8 KRAS HRAS BRCA2
4 12.32 TP53 KRAS HRAS BRCA1
5
Show member pathways
12.28 TP53 MUC1 KRAS HRAS
6
Show member pathways
12.15 TP53 KRAS HRAS BRCA2 BRCA1
7 11.84 TP53 KRAS HRAS
8 11.83 TP53 KRAS HRAS
9 11.8 TP53 KRAS HRAS
10 11.78 TP53 KRAS HRAS
11
Show member pathways
11.77 TP53 PGR KRAS HRAS BRCA2 BRCA1
12
Show member pathways
11.76 PGR KRAS HRAS
13
Show member pathways
11.57 TP53 BRCA2 BRCA1
14 11.5 TP53 KRAS HRAS
15 11.45 TP53 KRAS HRAS
16 11.44 TP53 KRAS BRCA2 BRCA1
17 11.41 TP53 KRAS HRAS
18 11.32 TP53 HRAS BRCA1
19 10.91 KRAS HRAS
20 10.88 TP53 BRCA1
21 10.8 PAX8 PAX2
22 10.65 KRAS HRAS

GO Terms for Endosalpingiosis

Cellular components related to Endosalpingiosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.7 WT1 TP53 PGR OVGP1 MUC1 KRT7
2 nucleus GO:0005634 9.36 WT1 TP53 PGR PAX8 PAX2 MUC1
3 lateral element GO:0000800 9.16 BRCA2 BRCA1

Biological processes related to Endosalpingiosis according to GeneCards Suite gene sharing:

(show all 34)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 10.04 WT1 TP53 PGR PAX8 PAX2 HRAS
2 positive regulation of gene expression GO:0010628 9.97 WT1 TP53 KRAS HRAS BRCA1
3 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.83 MUC1 KRAS HRAS
4 Ras protein signal transduction GO:0007265 9.8 TP53 KRAS HRAS
5 double-strand break repair GO:0006302 9.78 TP53 BRCA2 BRCA1
6 positive regulation of transcription, DNA-templated GO:0045893 9.73 WT1 TP53 PAX8 PAX2 BRCA2 BRCA1
7 branching involved in ureteric bud morphogenesis GO:0001658 9.7 WT1 PAX8 PAX2
8 response to X-ray GO:0010165 9.66 TP53 BRCA2
9 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.66 PAX8 PAX2
10 urogenital system development GO:0001655 9.65 PAX8 PAX2
11 mesonephros development GO:0001823 9.65 PAX8 PAX2
12 mesenchymal to epithelial transition GO:0060231 9.64 WT1 PAX2
13 metanephric mesenchyme development GO:0072075 9.64 WT1 PAX2
14 cellular response to gonadotropin stimulus GO:0071371 9.63 WT1 PAX8
15 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.62 TP53 MUC1
16 response to isolation stress GO:0035900 9.62 KRAS HRAS
17 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.61 PAX8 PAX2
18 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.6 PAX8 PAX2
19 pronephros development GO:0048793 9.59 PAX8 PAX2
20 metanephric S-shaped body morphogenesis GO:0072284 9.58 WT1 PAX8
21 chordate embryonic development GO:0043009 9.58 BRCA2 BRCA1
22 metanephric nephron tubule formation GO:0072289 9.56 PAX8 PAX2
23 metanephric distal convoluted tubule development GO:0072221 9.55 PAX8 PAX2
24 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.54 PAX8 PAX2
25 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.51 PAX8 PAX2
26 cell aging GO:0007569 9.5 TP53 HRAS BRCA2
27 positive regulation of metanephric DCT cell differentiation GO:2000594 9.48 PAX8 PAX2
28 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.46 PAX8 PAX2
29 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.43 PAX8 PAX2
30 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 9.4 PAX8 PAX2
31 pronephric field specification GO:0039003 9.37 PAX8 PAX2
32 negative regulation of reactive oxygen species metabolic process GO:2000378 9.33 TP53 PAX2 BRCA1
33 metanephric epithelium development GO:0072207 9.13 WT1 PAX8 PAX2
34 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.92 TP53 MUC1 BRCA2 BRCA1

Molecular functions related to Endosalpingiosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 9.7 WT1 TP53 PGR PAX8 PAX2 BRCA2
2 DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 9.65 WT1 TP53 PGR PAX8 PAX2
3 transcription regulatory region sequence-specific DNA binding GO:0000976 9.35 WT1 TP53 PAX8 PAX2 BRCA1
4 transcription regulatory region DNA binding GO:0044212 9.02 WT1 TP53 PAX8 PAX2 BRCA1

Sources for Endosalpingiosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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