MCID: ENT003
MIFTS: 38

Enterobiasis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Enterobiasis

MalaCards integrated aliases for Enterobiasis:

Name: Enterobiasis 12 73 15 17 70 32
Oxyuriasis 12 44 70
Enterobius Vermicularis Infection 12 3
Pinworm Infection 12 3
Oxyuris Vermicularis Infection 12
Threadworm Infection 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7457
MeSH 44 D010123
SNOMED-CT 67 154415009
ICD10 32 B80
UMLS 70 C0030100 C0086227

Summaries for Enterobiasis

CDC : 3 Pinworm infection is caused by a small, thin, white roundworm called Enterobius vermicularis. Although pinworom infection can affect all people, it most commonly occurs among children, institutionalized persons, and household members of persons with pinworm infection. Pinworm infection is treatable with over-the-counter or prescription medication, but reinfection, which occurs easily, should be prevented.

MalaCards based summary : Enterobiasis, also known as oxyuriasis, is related to strongyloidiasis and taeniasis, and has symptoms including fever and pruritus. An important gene associated with Enterobiasis is DACH2 (Dachshund Family Transcription Factor 2), and among its related pathways/superpathways are S33 mutants of beta-catenin arent phosphorylated and mTOR signaling pathway (KEGG). The drug Lithium carbonate has been mentioned in the context of this disorder. Affiliated tissues include appendix, ovary and uterus, and related phenotype is digestive/alimentary.

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves infection of the anus by the pinworm Enterobius vermicularis. The major symptom is perianal itching. Infected people experience perianal pruritus and excoriations from scratching.

Wikipedia : 73 Pinworm infection, also known as enterobiasis, is a human parasitic disease caused by the pinworm. The... more...

Related Diseases for Enterobiasis

Diseases related to Enterobiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
# Related Disease Score Top Affiliating Genes
1 strongyloidiasis 30.9 TES MT-CO1 IL4
2 taeniasis 29.7 TES MT-CO1 IL4
3 ancylostomiasis 29.7 TES MT-CO1
4 hymenolepiasis 29.6 TES MT-CO1
5 parasitic helminthiasis infectious disease 29.5 TES MT-CO1 IL4
6 ascaridiasis 10.5
7 ascaris lumbricoides infection 10.5
8 appendicitis 10.3
9 alcohol dependence 10.2
10 leukemia, chronic lymphocytic 10.2
11 deficiency anemia 10.2
12 fibroma 10.2
13 ileocolitis 10.2
14 ectopic pregnancy 10.2
15 benign teratoma 10.2
16 salpingo-oophoritis 10.2
17 leukemia 10.2
18 leiomyoma 10.2
19 cystic teratoma 10.2
20 vaginal discharge 10.2
21 infertility 10.2
22 mature teratoma 10.2
23 salpingitis 10.2
24 reactive arthritis 10.2
25 arthritis 10.2
26 pediatric acute-onset neuropsychiatric syndrome 10.2
27 giardiasis 10.1
28 trichuriasis 10.1
29 osteopathia striata with cranial sclerosis 10.0 LRP6 AXIN1
30 echinococcosis 10.0
31 vulvovaginitis 10.0
32 hypereosinophilic syndrome 10.0
33 mite infestation 10.0 MT-CO1 IL4
34 rectum cancer 10.0
35 dermatitis 10.0
36 bruxism 10.0
37 trichinosis 10.0
38 angiostrongyliasis 10.0 MT-CO1 IL4
39 urinary tract infection 10.0
40 tick infestation 9.9 MT-CO1 IL4
41 filarial elephantiasis 9.9 MT-CO1 IL4
42 cysticercosis 9.9 MT-CO1 IL4
43 gnathomiasis 9.9 TES MT-CO1
44 sparganosis 9.9 TES MT-CO1
45 intestinal schistosomiasis 9.9 MT-CO1 IL4
46 osteoporosis-pseudoglioma syndrome 9.9 LRP6 AXIN1
47 paragonimiasis 9.9 TES MT-CO1
48 intestinal obstruction 9.9
49 48,xyyy 9.9
50 parasitic ectoparasitic infectious disease 9.9 MT-CO1 IL4

Graphical network of the top 20 diseases related to Enterobiasis:



Diseases related to Enterobiasis

Symptoms & Phenotypes for Enterobiasis

UMLS symptoms related to Enterobiasis:


fever; pruritus

MGI Mouse Phenotypes related to Enterobiasis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.02 AXIN1 CSNK1A1 IL4 LRP6 TES

Drugs & Therapeutics for Enterobiasis

Drugs for Enterobiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lithium carbonate Approved 554-13-2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of Relationship Between Enterobius Vermicularis Infection and Bruxism in Children Completed NCT03833505

Search NIH Clinical Center for Enterobiasis

Inferred drug relations via UMLS 70 / NDF-RT 51 :


Albendazole
Ivermectin
Mebendazole
Pyrantel
Pyrantel Pamoate

Cochrane evidence based reviews: oxyuriasis

Genetic Tests for Enterobiasis

Anatomical Context for Enterobiasis

MalaCards organs/tissues related to Enterobiasis:

40
Appendix, Ovary, Uterus

Publications for Enterobiasis

Articles related to Enterobiasis:

(show top 50) (show all 836)
# Title Authors PMID Year
1
Helminth infections in the United States military: from strongyloidiasis to schistosomiasis. 61
33480433 2021
2
Prevalence and Age Distribution of Enterobiasis in North-Eastern Bulgaria. 61
32518486 2020
3
Impact of Enterobius vermicularis infection on biochemical parameters in the blood of children in Erbil Province, Iraq. 61
32397998 2020
4
Prevalence of Intestinal Parasitic Infections among the Bulgarian Population Over a Three Year Period (2015 - 2017). 61
32063735 2020
5
Enterobius vermicularis Infestation Mimicking Rectal Malignancy 61
32212596 2020
6
Epidemiology of Parasitic Infections in the West Bank and Gaza Strip, Palestine. 61
31769396 2020
7
Ileocolonic Lymphonodular Hyperplasia in Children Related to Etiologies Ranging from Food Hypersensitivity to Familial Mediterranean Fever. 61
32000163 2020
8
[National surveillance on Enterobius vermicularis infections among children at ages of 3 to 9 years in China from 2016 to 2018]. 61
32185928 2020
9
Confusing a Pollen Grain with a Parasite Egg: an Appraisal of "Paleoparasitological Evidence of Pinworm (Enterobius Vermicularis) Infection in a Female Adolescent Residing in Ancient Tehran". 61
31914514 2019
10
Papular eruption on UV-exposed skin in a 7-year-old boy caused by Enterobius vermicularis infection. 61
31855273 2019
11
The Diagnosis and Treatment of Pinworm Infection. 61
31064642 2019
12
Sweet syndrome in association with enterobiasis. 61
30187540 2019
13
Peripheral Eosinophilia Found in Pediatric Enterobius vermicularis Infections. 61
30280584 2019
14
The Incidence of Pinworm (Enterobius Vermicularis) in Pre-school and School Aged Children in the Eastern Slovakia. 61
31662658 2018
15
Gynecological and obstetrical aspects of Enterobius vermicularis infection. 61
29552897 2018
16
Worm Infestation: Diagnosis, Treatment and Prevention. 61
29127616 2018
17
Genetic variation of Enterobius vermicularis among schoolchildren in Thailand. 61
30369341 2018
18
Extraintestinal Oxyuriasis. 61
29807567 2018
19
Vaginal Enterobius vermicularis diagnosed on liquid-based cytology during Papanicolaou test cervical cancer screening: A report of two cases and a review of the literature. 61
28905520 2018
20
[Epidemiological features of parasitary invasis in women of reproductive age with disorders of reproductive health]. 61
29783245 2018
21
Human Parasitic Diseases in Bulgaria in Between 2013-2014. 61
28903890 2018
22
Inhibitory effect of pyrvinium pamoate on uveal melanoma cells involves blocking of Wnt/β-catenin pathway. 61
28981601 2017
23
Enterobius vermicularis in the Endometrium of the Uterus: A Case Report. 61
29317890 2017
24
Impact of Enterobius vermicularis infection and mebendazole treatment on intestinal microbiota and host immune response. 61
28945752 2017
25
Aqueous extract of Codium fragile suppressed inflammatory responses in lipopolysaccharide-stimulated RAW264.7 cells and carrageenan-induced rats. 61
28738499 2017
26
[Enterobius vermicularis enteroparasite role in appendicitis cecal: Enterobiasis and appendicitis]. 61
29890104 2017
27
Identifying Helminth Infections via Routine Fecal Parasitological Examinations in Korea. 61
28749758 2017
28
Epidemiology of Enterobius vermicularis infection among elementary school children in Hualien, Taiwan from 2007 to 2012. 61
33592992 2017
29
Spatial Distribution and Trends of Waterborne Diseases in Tashkent Province. 61
29138738 2017
30
A case of enterobiasis presenting as post-traumatic-stress-disorder (PTSD): a curious case of the infection with predominant mental health symptoms, presenting for the first time in the settings of a refugee camp. 61
28819532 2017
31
Prevalence of Enterobius vermicularis infection among preschool children, Babol, North of Iran. 61
27876982 2016
32
Prevalence of Enterobius vermicularis amongst kindergartens and preschool children in Mazandaran Province, North of Iran. 61
27876942 2016
33
[Demographic and clinical features of diagnosed individuals of enterobiasis in the southern Gran Canaria: sampling assessment]. 61
27714399 2016
34
Cutaneous Manifestations of Selected Parasitic Infections in Western Pacific and Southeast Asian Regions. 61
27447892 2016
35
Co-infection with Enterobius vermicularis and Taenia saginata mimicking acute appendicitis. 61
26754203 2016
36
[EXTERNAL QUALITY ASSESSMENT FOR THE LABORATORY IDENTIFICATION OF THE PATHOGENS OF PARASITIC DISEASES AS AN ELEMENT FOR IMPROVING THE POSTGRADUATE TRAINING OF SPECIALISTS]. 61
27405216 2016
37
Appendicitis by Enterobius vermicularis presenting with recurrent abdominal pain and eosinophilia A case report. 61
27585284 2016
38
Incidental diagnosis of oxyuriasis through a colonoscopy. 61
27077026 2016
39
Prevalence of Enterobius vermicularis among preschool children in 2003 and 2013 in Xinxiang city, Henan province, Central China. 61
27460881 2016
40
[Investigation of Intestinal Parasites and Level of Hygiene Knowledge of School Students]. 61
26809914 2015
41
[EXPERIENCE IN TREATING HELMINTHISM WITH MICRONIZED ALBENDAZOLE (GELMODOL)]. 61
26827590 2015
42
SCHISTOSOMIASIS IN NAG HAMMADY CITY, RELATIONSHIP BETWEEN INFECTION AND ANEMIA AMONG CHILDREN AND YOUTH, QENA GOVERNORATE, EGYPT. 61
26485859 2015
43
Worm Infections in Children. 61
26232464 2015
44
Negligible Egg Positive Rate of Enterobius vermicularis and No Detection of Head Lice among Orphanage Children in Busan and Ulsan, Korea (2014). 61
26323851 2015
45
INTESTINAL PARASITIC INFECTIONS AND ATOPIC DISEASES IN CHILDREN: A HOSPITAL BASED STUDY. 61
26485861 2015
46
Parasitic colitis. 61
26034403 2015
47
Enterobius vermicularis: an unusual cause of recurrent urinary tract infestation in a 7-year-old girl: case report and review of the literature. 61
25586573 2015
48
The prevalence of intestinal parasites in children in preschools and orphanages in the Warmia-Masuria province (North-Eastern Poland). 61
26519844 2015
49
Enterobiasis: threadworm infection presenting as acute appendicitis in a 13-year-old girl. 61
25589531 2015
50
Enterobiasis and strongyloidiasis and associated co-infections and morbidity markers in infants, preschool- and school-aged children from rural coastal Tanzania: a cross-sectional study. 61
25486986 2014

Variations for Enterobiasis

Expression for Enterobiasis

Search GEO for disease gene expression data for Enterobiasis.

Pathways for Enterobiasis

Pathways related to Enterobiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.13 LRP6 CSNK1A1 AXIN1
2
Show member pathways
12.08 LRP6 CSNK1A1 AXIN1
3 11.98 LRP6 CSNK1A1 AXIN1
4 11.8 LRP6 CSNK1A1 AXIN1
5 11.65 LRP6 CSNK1A1 AXIN1
6 10.86 LRP6 CSNK1A1 AXIN1
7 10.7 LRP6 CSNK1A1
8 10.46 LRP6 CSNK1A1 AXIN1
9 10.41 CSNK1A1 AXIN1

GO Terms for Enterobiasis

Cellular components related to Enterobiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 beta-catenin destruction complex GO:0030877 8.62 CSNK1A1 AXIN1

Biological processes related to Enterobiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Wnt signaling pathway GO:0016055 9.43 LRP6 CSNK1A1 AXIN1
2 negative regulation of canonical Wnt signaling pathway GO:0090090 9.33 LRP6 CSNK1A1 AXIN1
3 beta-catenin destruction complex assembly GO:1904885 8.96 CSNK1A1 AXIN1
4 beta-catenin destruction complex disassembly GO:1904886 8.8 LRP6 CSNK1A1 AXIN1

Sources for Enterobiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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