MCID: ENT011
MIFTS: 55

Enterocolitis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Enterocolitis

MalaCards integrated aliases for Enterocolitis:

Name: Enterocolitis 58 30 56 17 74

Characteristics:

OMIM:

58
Inheritance:
autosomal recessive


HPO:

33
enterocolitis:
Inheritance autosomal recessive inheritance


Classifications:



External Ids:

OMIM 58 226150
ICD10 34 A04.7
MedGen 43 C0014356
UMLS 74 C0014356

Summaries for Enterocolitis

MalaCards based summary : Enterocolitis is related to autoinflammation with infantile enterocolitis and perinatal necrotizing enterocolitis. An important gene associated with Enterocolitis is NLRC4 (NLR Family CARD Domain Containing 4), and among its related pathways/superpathways are Innate Immune System and Complement and coagulation cascades. The drugs Ceftriaxone and Betamethasone have been mentioned in the context of this disorder. Affiliated tissues include colon, heart and breast, and related phenotypes are hematochezia and abdominal distention

Wikipedia : 77 Enterocolitis or coloenteritis is an inflammation of the digestive tract, involving enteritis of the... more...

Description from OMIM: 226150

Related Diseases for Enterocolitis

Diseases related to Enterocolitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 293)
# Related Disease Score Top Affiliating Genes
1 autoinflammation with infantile enterocolitis 34.5 NLRC4 SLC30A6
2 perinatal necrotizing enterocolitis 34.5 FABP2 TLR4
3 ileitis 30.0 FABP2 TLR4
4 salmonellosis 29.6 NLRC4 TLR4
5 hemolytic uremic syndrome, atypical 1 29.2 C3 CD46 CFB CFH CFHR1 CFHR3
6 hemolytic-uremic syndrome 27.3 C3 CD46 CFB CFH CFHR1 CFHR3
7 mastocytic enterocolitis 12.4
8 clostridium difficile colitis 11.8
9 short bowel syndrome 11.4
10 hirschsprung disease 1 11.4
11 hypoganglionosis 11.3
12 5-oxoprolinase deficiency 11.0
13 pigmentary disorder, reticulate, with systemic manifestations, x-linked 11.0
14 hemolytic uremic syndrome, atypical 2 11.0
15 hemolytic uremic syndrome, atypical 3 11.0
16 hemolytic uremic syndrome, atypical 4 11.0
17 hemolytic uremic syndrome, atypical 5 11.0
18 hemolytic uremic syndrome, atypical 6 11.0
19 intestinal perforation 10.5
20 leukemia 10.4
21 heart disease 10.3
22 familial cold autoinflammatory syndrome 10.3 NLRC4 SLC30A6
23 familial cold autoinflammatory syndrome 4 10.3 NLRC4 SLC30A6
24 diarrhea 10.3
25 hypoxia 10.3
26 colitis 10.3
27 legionnaires' disease 10.2 NLRC4 TLR4
28 appendicitis 10.2
29 ischemia 10.2
30 intussusception 10.2
31 acute leukemia 10.2
32 inflammatory bowel disease 10.2
33 arthritis 10.1
34 crohn's disease 10.1
35 legionellosis 10.1 NLRC4 TLR4
36 de novo thrombotic microangiopathy after kidney transplantation 10.1 CFH CFI
37 familial drusen 10.1 CFH CFI
38 patent ductus arteriosus 1 10.1
39 proliferative glomerulonephritis 10.1 C3 CFH
40 complement component 3 deficiency 10.1 C3 CFI
41 leukemia, acute myeloid 10.1
42 milk allergy 10.1
43 myeloid leukemia 10.1
44 complement factor i deficiency 10.1 C3 CFI
45 multifocal choroiditis 10.1 CFB CFH
46 choroiditis 10.0 CFB CFH
47 neutropenia 10.0
48 thrombocytopenia 10.0
49 megacolon 10.0
50 gastroenteritis 10.0

Graphical network of the top 20 diseases related to Enterocolitis:



Diseases related to Enterocolitis

Symptoms & Phenotypes for Enterocolitis

Human phenotypes related to Enterocolitis:

33
# Description HPO Frequency HPO Source Accession
1 hematochezia 33 HP:0002573
2 abdominal distention 33 HP:0003270
3 ulcerative colitis 33 HP:0100279
4 enterocolitis 33 HP:0004387

Symptoms via clinical synopsis from OMIM:

58
G I:
ulcerative colitis
bloody diarrhea
pseudomembranous enterocolitis

Abdomen:
swelling

Clinical features from OMIM:

226150

MGI Mouse Phenotypes related to Enterocolitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.1 C3 CFB CFH CFI FABP2 TLR4

Drugs & Therapeutics for Enterocolitis

Drugs for Enterocolitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 361)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
2
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 378-44-9 9782
3
Progesterone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 57-83-0 5994
4
Ibuprofen Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 15687-27-1 3672
5
Caffeine Approved Phase 4,Phase 3,Phase 2,Not Applicable 58-08-2 2519
6
Sodium Citrate Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 68-04-2
7 Poractant alfa Approved Phase 4,Not Applicable 129069-19-8
8
Indomethacin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 53-86-1 3715
9
Adalimumab Approved Phase 4 331731-18-1 16219006
10
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-02-2 5743
11
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 1177-87-3
12
Nystatin Approved, Vet_approved Phase 4 1400-61-9 11953884
13
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 22916-47-8 4189
14
Iodine Approved, Investigational Phase 4 7553-56-2 807
15
Zinc Approved, Investigational Phase 4 7440-66-6 32051
16
Nifedipine Approved Phase 4,Phase 3,Not Applicable 21829-25-4 4485
17
Metronidazole Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 443-48-1 4173
18
Labetalol Approved Phase 4,Phase 2,Phase 3 36894-69-6 3869
19
Methyldopa Approved Phase 4 555-30-6 38853
20
Calcium Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Not Applicable 7440-70-2 271
21
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 77-92-9 311
22
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
23
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 1406-16-2
24
Vitamin D3 Approved, Nutraceutical Phase 4,Phase 2,Phase 3 67-97-0 5280795 6221
25
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3 50-14-6 5280793
26
Beta carotene Approved, Nutraceutical Phase 4 7235-40-7
27 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
28 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
29 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
30 Cathartics Phase 4,Phase 1,Phase 2
31 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
32 Laxatives Phase 4,Phase 1,Phase 2
33 Polyethylene glycol 3350 Phase 4,Not Applicable
34 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Betamethasone benzoate Phase 4,Phase 3,Phase 2,Not Applicable
37 Betamethasone sodium phosphate Phase 4,Phase 3,Phase 2,Not Applicable
38 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
39 Hormones Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
40 Betamethasone-17,21-dipropionate Phase 4,Phase 3,Phase 2,Not Applicable
41 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
43 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
44 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
45 Betamethasone Valerate Phase 4,Phase 3,Phase 2,Not Applicable 2152-44-5
46 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
47 Acidophilus Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable
48 Progestins Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
49 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 576)
# Name Status NCT ID Phase Drugs
1 The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis Unknown status NCT01278017 Phase 4 ceftriaxone
2 Withholding Feeds During Red Blood Cell Transfusion and TRAGI Unknown status NCT02132819 Phase 4
3 The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease) Unknown status NCT01765998 Phase 4 Probiotic;Placebo
4 Clostridial Infection and Oral Lavage -Improving Treatment Before Illness Becomes Severe Unknown status NCT01630096 Phase 4 Nu-Lytely
5 Cpap at Delivery Room for Preterm Infants Unknown status NCT01024361 Phase 4
6 Effect of Probiotics (Bio-Three) in Children's Enterocolitis Completed NCT00463190 Phase 4 Biothree
7 Intestinal Inflammation in Ankylosing Spondylitis and the Effects of Adalimumab on Mucosal Healing Completed NCT01174186 Phase 4 Adalimumab
8 Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis Completed NCT02959229 Phase 4 Lactoferrin;Placebo (for Lactoferrin)
9 A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome Completed NCT00201643 Phase 4 Betamethasone or Dexamethasone (2nd course of ACS);Placebo
10 Comparison of Lactobacillus Reuteri and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight Infants Completed NCT01531192 Phase 4 Nystatin
11 A Randomised Controlled Trial of Iodide Supplementation in Preterm Infants Follow-up at 2 Years Completed NCT00638092 Phase 4 sodium iodide;Sodium Chloride
12 Efficacy of 17 Alpha-hydroxyprogesterones Caproate for the Prevention of Preterm Delivery Completed NCT00331695 Phase 4 17 alpha-hydroxyprogesterones caproate
13 Ibuprofen and Renal Function in Premature Infants Completed NCT00217191 Phase 4 Ibuprofen
14 Impact of Oral Application of Gastrografin on the Meconium Evacuation in Very Low Birth Weight Infants Completed NCT01515696 Phase 4 Gastrografin;Sterile water
15 Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IV Completed NCT01604447 Phase 4
16 Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates Completed NCT01403623 Phase 4
17 MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine Completed NCT00809055 Phase 4 Caffeine citrate
18 Melatonin to Prevent Brain Injury in Unborn Growth Restricted Babies Completed NCT01695070 Phase 4 Melatonin
19 Probiotics for Prophylaxis of Postoperative Hirschsprungs Associated Enterocolitis Recruiting NCT02343562 Phase 4
20 The Effect of β-Carotene, Vitamin D3 and Zinc on Hyaline Membrane Disease and Feeding Intolerance in Premature Neonates Recruiting NCT03366584 Phase 4 Dexamethasone
21 OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP Recruiting NCT02140580 Phase 4
22 Vaginal Progesterone for the Prolongation of Pregnancy After Arrested Pre-term Labor Recruiting NCT02430233 Phase 4 micronized progesterone 400 mg (Utrogestan)
23 Vaginal Versus Intramuscular Progesterone for the Prevention of Recurrent Preterm Birth Recruiting NCT02913495 Phase 4 Vaginal Progesterone;Intramuscular Progesterone
24 Early Vascular Adjustments During Hypertensive Pregnancy Recruiting NCT02531490 Phase 4 Labetalol;Nifedipine;Methyldopa
25 TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence Recruiting NCT02621645 Phase 4
26 Chronic Hypertension and Pregnancy (CHAP) Project Recruiting NCT02299414 Phase 4 Anti-hypertensive therapy
27 Rate of Bronchopulmonary Dysplasia in Preterms Neonates: a Trial Comparing SMOFlipid and Medialipide Not yet recruiting NCT02853253 Phase 4
28 Comparing the Effectiveness of IV Bezlotoxumab Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant C. Diff Requiring Surgery. Not yet recruiting NCT03756454 Phase 4
29 The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study Terminated NCT00164099 Phase 4 Synbiotic 2000
30 Sodium Supplementation and Growth in Very Low Birth Weight Infants Terminated NCT01795638 Phase 4 Sodium chloride;Placebo
31 Removal Versus Retention of Cerclage in Preterm Premature Rupture of Membranes (PPROM) Terminated NCT00201656 Phase 4
32 Addition of Lactobacillus to Metronidazole in Treatment of CDAD Withdrawn NCT00304863 Phase 4 Lactobacillus GG
33 Pilot Study to Compare Fresh Frozen Plasma With 24-Hour Plasma in Babies Up to Age Six Months Withdrawn NCT02774317 Phase 4
34 RCT of Postoperative Infections Following Caesarean Section Infections Following Caesarean Section Withdrawn NCT02009098 Phase 4 Cefuroxime
35 Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature Babies Withdrawn NCT00470743 Phase 4 Ibuprofen;Indomethacin
36 Effect of Saccharomyces Boulardii on Necrotizing Enterocolitis in Very Low Birth Weight Infants Unknown status NCT01315821 Phase 3 Saccharomyces boulardii;Placebo
37 Randomized Study of Pessary Versus Standard Management in Women With Increased Chance of Premature Birth Unknown status NCT00735137 Phase 3
38 Cysteine Supplementation in Critically Ill Neonates Unknown status NCT00254176 Phase 2, Phase 3
39 Duration of Antibiotics Treatment With Cefazolin and Clarithromycin in Women With Preterm Premature Rupture of Membrane Unknown status NCT01503606 Phase 3 Cefazolin;Clarithromycin;Cefazolin;Clarithromycin
40 Clarithromycin Prophylaxis in Preterm Infants Colonisation With Ureaplasma Urealyticum and Mycoplasma Hominis Unknown status NCT01652118 Phase 3 clarithromycin treatment for prophylaxis of bronchopulmonary dysplasia;Saline
41 Prophylactic Acetaminophen for Prevention Intraventricular Hemorrhage in Premature Infants Unknown status NCT03024814 Phase 3 Acetaminophen;Dextrose 5
42 Progesterone and Cervical Pessary in Twins Unknown status NCT03058536 Phase 2, Phase 3 Vaginal Progesterone
43 Pessary as Adjunctive Therapy to Cerclage for the Prevention of Preterm Birth Unknown status NCT02678026 Phase 3
44 A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders Unknown status NCT02336243 Phase 3
45 Efficacy Study of Hypothermia Plus Magnesium Sulphate(MgSO4) in the Management of Term and Near Term Babies With Hypoxic Ischemic Encephalopathy Unknown status NCT01646619 Phase 3 Magnesium Sulphate;Placebo
46 Cerclage for Singletons With Short Cervix Without Prior Preterm Birth Unknown status NCT02716922 Phase 3
47 Modulation of the Intestinal Flora With the Probiotic VIVOMIXX™ in Pregnant Women at Risk of Metabolic Complications Unknown status NCT02768818 Phase 3
48 Lactobacillus Reuteri for Prevention of Necrotizing Enterocolitis in Very Low-birth Weight Infants Completed NCT01531179 Phase 3 Lactobacillus reuteri;Placebo
49 Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature Infants Completed NCT01868737 Phase 3
50 The Efficacy of Symbiotic on Cytokines Completed NCT01899677 Phase 3 symbiotic

Search NIH Clinical Center for Enterocolitis

Genetic Tests for Enterocolitis

Genetic tests related to Enterocolitis:

# Genetic test Affiliating Genes
1 Enterocolitis 30

Anatomical Context for Enterocolitis

MalaCards organs/tissues related to Enterocolitis:

42
Colon, Heart, Breast, Brain, Small Intestine, Cervix, Neutrophil

Publications for Enterocolitis

Articles related to Enterocolitis:

(show top 50) (show all 3543)
# Title Authors Year
1
Cytomegalovirus enterocolitis in a patient with dihydropyrimidine dehydrogenase deficiency after capecitabine treatment: A case report. ( 30831507 )
2019
2
Reliability of the Hirschsprung-Associated Enterocolitis Score in Clinical Practice. ( 30602191 )
2019
3
Milk Fat Globule Membrane Ameliorates Necrotizing Enterocolitis in Neonatal Rats and Suppresses Lipopolysaccharide-Induced Inflammatory Response in IEC-6 Enterocytes. ( 30613991 )
2019
4
Inhibition of HMGB1 improves necrotizing enterocolitis by inhibiting NLRP3 via TLR4 and NF-κB signaling pathways. ( 30618088 )
2019
5
Dysregulation of miR-431 and target gene FOXA1 in intestinal tissues of infants with necrotizing enterocolitis. ( 30624964 )
2019
6
Preventing brain damage in necrotizing enterocolitis. ( 30643226 )
2019
7
Associations between Red Blood Cell Transfusions and Necrotizing Enterocolitis in Very Low Birth Weight Infants: Ten-Year Data of a Tertiary Neonatal Unit. ( 30650594 )
2019
8
Fulminant pseudomembranous enterocolitis caused by Klebsiella oxytoca: an autopsy case report. ( 30652002 )
2019
9
Acute-on-chronic food protein-induced enterocolitis syndrome in an exclusively breast-fed infant. ( 30656011 )
2019
10
Regulation of ROS-NF-κB axis by tuna backbone derived peptide ameliorates inflammation in necrotizing enterocolitis. ( 30656693 )
2019
11
Food protein-induced enterocolitis syndrome: guidelines summary and practice recommendations. ( 30656696 )
2019
12
Necrotizing Enterocolitis and the Preterm Infant Microbiome. ( 30680646 )
2019
13
Cecal Hematoma Associated with Suspected Necrotizing Enterocolitis in a Neonate. ( 30686895 )
2019
14
Frequencies of Immune Cells in the Human Small Bowel During Normal Gestation and in Necrotizing Enterocolitis. ( 30689475 )
2019
15
Current Status of Necrotizing Enterocolitis. ( 30691547 )
2019
16
Degradation of Extracellular DNA Significantly Ameliorates Necrotizing Enterocolitis Severity in Mice. ( 30691836 )
2019
17
Serum TARC level as a potential biomarker for FPIES. ( 30697824 )
2019
18
Bovine milk-derived exosomes enhance goblet cell activity and prevent the development of experimental necrotizing enterocolitis. ( 30699187 )
2019
19
Langerhans Cell Histiocytosis Presenting as Enterocolitis and Shock in Neonate. ( 30720676 )
2019
20
Differentiating Acute Food Protein-Induced Enterocolitis Syndrome From Its Mimics: A Comparison of Clinical Features and Routine Laboratory Biomarkers. ( 30722841 )
2019
21
Feeding during transfusion and the risk of necrotizing enterocolitis in preterm infants. ( 30723281 )
2019
22
Food Protein-Induced Enterocolitis Syndrome: a Comprehensive Review. ( 30734159 )
2019
23
Recent advances in understanding necrotizing enterocolitis. ( 30740215 )
2019
24
Neutropenic Enterocolitis in Critically Ill Patients: Spectrum of the Disease and Risk of Invasive Fungal Disease. ( 30741755 )
2019
25
Emerging Triggers of FPIES: Lessons from a Pediatric Cohort of 74 Children in the US. ( 30742916 )
2019
26
Does the initial surgery for necrotizing enterocolitis matter? Comparative outcomes for laparotomy vs. peritoneal drain as initial surgery for necrotizing enterocolitis in infants <1000 g birth weight. ( 30765157 )
2019
27
Multidisciplinary evaluation of Clostridium butyricum clonality isolated from preterm neonates with necrotizing enterocolitis in South France between 2009 and 2017. ( 30765857 )
2019
28
Food Protein-Induced Enterocolitis Syndrome in South Tyrol 2012-2016: a population based study. ( 30767294 )
2019
29
Biomarker Discovery and Utility in Necrotizing Enterocolitis. ( 30771811 )
2019
30
Epidemiology of Necrotizing Enterocolitis: New Considerations Regarding the Influence of Red Blood Cell Transfusions and Anemia. ( 30771812 )
2019
31
Modifiable Risk Factors in Necrotizing Enterocolitis. ( 30771814 )
2019
32
Impact of Toll-Like Receptor 4 Signaling in Necrotizing Enterocolitis: The State of the Science. ( 30771815 )
2019
33
Challenges in Advancing Necrotizing Enterocolitis Research. ( 30771816 )
2019
34
Necrotizing Enterocolitis Pathophysiology: How Microbiome Data Alter Our Understanding. ( 30771817 )
2019
35
Influence of Growth Factors on the Development of Necrotizing Enterocolitis. ( 30771819 )
2019
36
Can Fish Oil Reduce the Incidence of Necrotizing Enterocolitis by Altering the Inflammatory Response? ( 30771820 )
2019
37
Oropharyngeal Mother's Milk: State of the Science and Influence on Necrotizing Enterocolitis. ( 30771821 )
2019
38
Does Surgical Management Alter Outcome in Necrotizing Enterocolitis? ( 30771822 )
2019
39
We Need to Stamp Out Necrotizing Enterocolitis. ( 30771823 )
2019
40
Improving Outcomes Due to Neonatal Necrotizing Enterocolitis. ( 30771824 )
2019
41
Drug Induced Enterocolitis Syndrome (DIES): a clinical entity which deserves more awareness. ( 30772389 )
2019
42
How to use abdominal X-rays in preterm infants suspected of developing necrotising enterocolitis. ( 30777865 )
2019
43
Long-term growth outcomes in neonates diagnosed with necrotizing enterocolitis: a 20-year analysis. ( 30782443 )
2019
44
High Stimulation Index for Quail Egg Yolk After an Allergen-Specific Lymphocyte Stimulation Test in a Child With Quail Egg-Induced Food Protein- Induced Enterocolitis Syndrome. ( 30785108 )
2019
45
Risk of Necrotizing Enterocolitis Following Packed Red Blood Cell Transfusion in Very Low Birth Weight Infants. ( 30790187 )
2019
46
Necrotizing enterocolitis. ( 30793842 )
2019
47
Early diagnosis of necrotizing enterocolitis by plasma RELMβ and thrombocytopenia in preterm infants: A pilot study. ( 30799148 )
2019
48
Factors influencing the incidence of Hirschsprung associated enterocolitis (HAEC). ( 30808539 )
2019
49
Survival rates for surgically treated necrotising enterocolitis have improved over the last four decades. ( 30825252 )
2019
50
Using formalin fixed paraffin embedded tissue to characterize the preterm gut microbiota in necrotising enterocolitis and spontaneous isolated perforation using marginal and diseased tissue. ( 30832576 )
2019

Variations for Enterocolitis

Expression for Enterocolitis

Search GEO for disease gene expression data for Enterocolitis.

Pathways for Enterocolitis

GO Terms for Enterocolitis

Cellular components related to Enterocolitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.73 C3 CFB CFH CFHR1 CFHR5 CFI
2 extracellular exosome GO:0070062 9.63 C3 CD46 CFB CFH CFHR3 CFI
3 extracellular space GO:0005615 9.43 C3 CFB CFH CFHR1 CFHR3 CFI
4 blood microparticle GO:0072562 9.02 C3 CFB CFH CFHR1 CFHR3

Biological processes related to Enterocolitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.72 C3 CD46 CFB NLRC4 TLR4
2 innate immune response GO:0045087 9.7 C3 CD46 CFB CFH CFI NLRC4
3 complement activation, classical pathway GO:0006958 9.61 C3 CD46 CFI
4 complement activation GO:0006956 9.56 C3 CFB CFH CFHR1
5 positive regulation of interleukin-10 production GO:0032733 9.48 CD46 TLR4
6 activation of innate immune response GO:0002218 9.46 NLRC4 TLR4
7 interleukin-1 beta secretion GO:0050702 9.4 NLRC4 TLR4
8 positive regulation of cytolysis GO:0045919 9.37 CFHR1 CFHR5
9 complement activation, alternative pathway GO:0006957 9.26 C3 CFB CFH CFHR5
10 regulation of complement activation GO:0030449 9.17 C3 CD46 CFB CFH CFHR1 CFHR5

Molecular functions related to Enterocolitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 8.8 C3 CFB CFI

Sources for Enterocolitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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