MCID: ENT011
MIFTS: 51

Enterocolitis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Enterocolitis

MalaCards integrated aliases for Enterocolitis:

Name: Enterocolitis 57 29 55 17 72

Characteristics:

OMIM:

57
Inheritance:
autosomal recessive


HPO:

32
enterocolitis:
Inheritance autosomal recessive inheritance


Classifications:



External Ids:

OMIM 57 226150
ICD10 33 A04.7
MedGen 42 C0014356
UMLS 72 C0014356

Summaries for Enterocolitis

MalaCards based summary : Enterocolitis is related to autoinflammation with infantile enterocolitis and perinatal necrotizing enterocolitis. An important gene associated with Enterocolitis is NLRC4 (NLR Family CARD Domain Containing 4), and among its related pathways/superpathways are Innate Immune System and Toll-like Receptor Signaling Pathway. The drugs Ceftriaxone and Adalimumab have been mentioned in the context of this disorder. Affiliated tissues include colon, breast and heart, and related phenotypes are hematochezia and abdominal distention

Wikipedia : 75 Enterocolitis is an inflammation of the digestive tract, involving enteritis of the small intestine and... more...

More information from OMIM: 226150

Related Diseases for Enterocolitis

Diseases related to Enterocolitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 580)
# Related Disease Score Top Affiliating Genes
1 autoinflammation with infantile enterocolitis 35.1 SLC30A6 NLRC4
2 perinatal necrotizing enterocolitis 34.7 TLR4 FABP2 CXCL8
3 ileitis 30.9 TLR4 FABP2
4 bacterial sepsis 30.7 TLR4 CXCL8
5 necrotizing fasciitis 30.3 CXCL8 CD46
6 fasciitis 30.3 CXCL8 CD46
7 pouchitis 30.2 TLR4 CXCL8
8 septic arthritis 30.1 TLR4 CXCL8
9 bacterial pneumonia 29.9 TLR4 CXCL8
10 pyelonephritis 29.9 TLR4 CXCL8
11 brucellosis 29.8 TLR4 CXCL8
12 neisseria meningitidis infection 29.6 TLR4 CD46 C3
13 hemolytic uremic syndrome, atypical 1 28.4 CFHR5 CFHR3 CFHR1 CFH CFB CD46
14 hemolytic-uremic syndrome 26.7 CFHR5 CFHR3 CFHR1 CFH CFB CD46
15 mastocytic enterocolitis 12.6
16 clostridium difficile colitis 11.9
17 short bowel syndrome 11.7
18 hirschsprung disease 1 11.6
19 inflammatory bowel disease 11.5
20 patent ductus arteriosus 1 11.5
21 hypoganglionosis 11.5
22 5-oxoprolinase deficiency 11.1
23 pigmentary disorder, reticulate, with systemic manifestations, x-linked 11.1
24 hemolytic uremic syndrome, atypical 2 11.1
25 hemolytic uremic syndrome, atypical 3 11.1
26 hemolytic uremic syndrome, atypical 4 11.1
27 hemolytic uremic syndrome, atypical 5 11.1
28 hemolytic uremic syndrome, atypical 6 11.1
29 diarrhea 10.8
30 intestinal perforation 10.7
31 neutropenia 10.6
32 peritonitis 10.6
33 food allergy 10.6
34 familial cold autoinflammatory syndrome 4 10.6 SLC30A6 NLRC4
35 familial cold autoinflammatory syndrome 10.6 SLC30A6 NLRC4
36 crohn's disease 10.6
37 colitis 10.5
38 intestinal disease 10.5
39 superficial urinary bladder cancer 10.5 TLR4 CXCL8
40 periodontosis 10.5 TLR4 CXCL8
41 intestinal obstruction 10.5
42 pyelitis 10.5 TLR4 CXCL8
43 gastroenteritis 10.5
44 ileus 10.5
45 endometrial disease 10.4 TLR4 CXCL8
46 overgrowth syndrome 10.4
47 bacteriuria 10.4 TLR4 CXCL8
48 ulcerative colitis 10.4
49 middle ear disease 10.4 TLR4 CXCL8
50 acute leukemia 10.4

Graphical network of the top 20 diseases related to Enterocolitis:



Diseases related to Enterocolitis

Symptoms & Phenotypes for Enterocolitis

Human phenotypes related to Enterocolitis:

32
# Description HPO Frequency HPO Source Accession
1 hematochezia 32 HP:0002573
2 abdominal distention 32 HP:0003270
3 ulcerative colitis 32 HP:0100279
4 enterocolitis 32 HP:0004387

Symptoms via clinical synopsis from OMIM:

57
G I:
ulcerative colitis
bloody diarrhea
pseudomembranous enterocolitis

Abdomen:
swelling

Clinical features from OMIM:

226150

MGI Mouse Phenotypes related to Enterocolitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.02 C3 CFB CFH FABP2 TLR4

Drugs & Therapeutics for Enterocolitis

Drugs for Enterocolitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 250)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
2
Adalimumab Approved Phase 4 331731-18-1 16219006
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
4
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
5
Histamine Approved, Investigational Phase 4 51-45-6 774
6
Ranitidine Approved Phase 4 66357-35-5, 66357-59-3 3001055
7
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
8
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
9
Zinc Approved, Investigational Phase 4 7440-66-6 32051
10
Zinc sulfate Approved, Investigational Phase 4 7733-02-0
11
Tocopherol Approved, Investigational Phase 4 1406-66-2, 54-28-4 14986
12 Poractant alfa Approved Phase 4 129069-19-8
13
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
14 Beractant Approved Phase 4 108778-82-1
15
Sorbitol Approved Phase 4 50-70-4 5780
16 Coconut Approved Phase 4
17
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 6221 5280795
18
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
19
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
20
Beta carotene Approved, Nutraceutical Phase 4 7235-40-7
21
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
22 Tocotrienol Investigational Phase 4 6829-55-6
23 Polyethylene glycol 3350 Phase 4
24 gamma-Globulins Phase 4
25 Immunoglobulins, Intravenous Phase 4
26 Rho(D) Immune Globulin Phase 4
27 Antibiotics, Antitubercular Phase 4
28 Antitubercular Agents Phase 4
29 Antiemetics Phase 4
30 Vitamin D2 Phase 4
31 Carotenoids Phase 4
32 Antineoplastic Agents, Hormonal Phase 4
33 Provitamins Phase 4
34
Picolinic acid Phase 4 98-98-6 1018
35 Ergocalciferols Phase 4
36 Calciferol Phase 4
37 BB 1101 Phase 4
38 Bone Density Conservation Agents Phase 4
39 Antacids Phase 4
40 Anti-Ulcer Agents Phase 4
41
Stevioside Phase 4 57817-89-7 548198
42 Stevia Phase 4
43
Histamine Phosphate Phase 4 51-74-1 65513
44 Histamine Antagonists Phase 4
45 Bismuth tripotassium dicitrate Phase 4
46 Histamine H2 Antagonists Phase 4
47
Bismuth Phase 4 7440-69-9 16682734 105143
48 Ranitidine bismuth citrate Phase 4
49 Amoxicillin-Potassium Clavulanate Combination Phase 4
50 beta-Lactamase Inhibitors Phase 4

Interventional clinical trials:

(show top 50) (show all 418)
# Name Status NCT ID Phase Drugs
1 The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis Unknown status NCT01278017 Phase 4 ceftriaxone
2 The Effect of Withholding Feeds During Red Blood Cell Transfusion on Development of TRAGI in Very Low Birth Weight Infants Unknown status NCT02132819 Phase 4
3 The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation (Crohn's Disease) and Markers of Inflammation Unknown status NCT01765998 Phase 4 Probiotic;Placebo
4 THE EFFECT OF SUSTAINED LUNG INFLATION MANEUVER APPLIED THROUGH NASAL PRONG ON EARLY AND LATE RESPIRATORY MORBIDITIES IN PRETERM INFANTS Unknown status NCT02887924 Phase 4
5 Gut-kidney Axis: Renal Effects of Meditarranean Diet and Low-protein Diet With Ketoacids to Restore Physiological Intestinal Mibrobiota in Chronic Kidney Disease Unknown status NCT02302287 Phase 4
6 COLITIS: Clostridial Infection and Oral Lavage -Improving Treatment Before Illness Becomes Severe Unknown status NCT01630096 Phase 4 Nu-Lytely
7 Postmarketing Study of Probiotics Medication in Childhood Diarrhea Completed NCT00463190 Phase 4 Biothree
8 Systematic Randomized , Single Blinded, Placebo-Controlled Trial of Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis Completed NCT02959229 Phase 4 Lactoferrin;Placebo (for Lactoferrin)
9 A Randomized Trial to Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates in Developing Countries Completed NCT01403623 Phase 4
10 Randomized Evaluation of the Use of Plastic Bags to Prevent Neonatal Hypothermia in Developing Countries-Part IV Completed NCT01604447 Phase 4
11 Intestinal Inflammation in Ankylosing Spondylitis Assessed by Fecal Calprotectin, Capsular Endoscopy and Colonoscopy and the Effects of Adalimumab on Mucosal Healing Completed NCT01174186 Phase 4 Adalimumab
12 A Randomized Double-Blinded Study Comparing the Impact of One Versus Two Courses of Antenatal Steroids on Neonatal Outcome Completed NCT00201643 Phase 4 Betamethasone or Dexamethasone (2nd course of ACS);Placebo
13 Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory Distress Completed NCT00486850 Phase 4
14 Phase 4 Study of Use of High-dose Intravenous Immune Globulin for Prevent Hyperbilirubinemia Due Rh Hemolytic Disease in Newborns Infants Completed NCT00288600 Phase 4 Intravenous Immunoglobulin;Normal saline solution
15 Probiotics for Prophylaxis of Postoperative Hirschsprungs Associated Enterocolitis Recruiting NCT02343562 Phase 4
16 The Effect of Co-administered β-Carotene, Vitamin D3, Zinc and Antenatal Steroid Therapy on Hyaline Membrane Disease and Feeding Intolerance in Premature Neonates Recruiting NCT03366584 Phase 4 Dexamethasone
17 Early Sodium Intake in Preterm Newborns; Randomized Clinical Trial Recruiting NCT04035564 Phase 4 Sodium < 1mEq/kg/day;Sodium 5mEq/kg/day
18 Stress Ulcer Prophylaxis Versus Placebo - a Blinded Randomized Control Trial to Evaluate the Safety of Two Strategies in Critically Ill Infants With Congenital Heart Disease Recruiting NCT03667703 Phase 4 Ranitidine;Placebo
19 Multicentre Randomised Controlled Trial of Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on Continuous Positive Airways Pressure Recruiting NCT02140580 Phase 4
20 Effect of Lactobacillus Reuteri DSM 17938 to Prevent Antibiotic-associated Diarrhea in Children: Prospective, Multi-center, Randomize, Parallel Group Placebo Controlled Clinical Trial Recruiting NCT02765217 Phase 4 Lactobacillus reuteri DSM 17938;Placebo;Amoxicillin-Clavulanic Acid
21 Oral Zinc Supplementation Improving Growth and Reducing Morbidity on Very Low Birth Weight Infant Not yet recruiting NCT04050488 Phase 4 Zinc Sulfate;Placebos
22 Personalized Versus Standardized Parenteral Nutrition for Preterm Infants With a Birth Weight Greater Than 1250 Grams: a Multicenter Randomized Phase IV Clinical Trial Not yet recruiting NCT03693287 Phase 4 Standardized-parenteral nutrition (S-PN);Personalized-parenteral nutrition (P-PN)
23 A Prospective, Double-blind, Randomized, and Controlled Clinical Trial to Compare the Effectiveness of Intravenous Bezlotoxumab (10 mg/kg) Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant Clostridioides Difficile Requiring Surgical Intervention. Not yet recruiting NCT03756454 Phase 4
24 The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study Terminated NCT00164099 Phase 4 Synbiotic 2000
25 Impact of Early Postnatal Sodium Supplementation on Weight Gain in Very Low Birth Weight Infants Terminated NCT01795638 Phase 4 Sodium chloride;Placebo
26 Phase 4 Study of Curosurf (Poractant) and Survanta (Beractant) Surfactant Treatment in Very Premature Infants With Respiratory Distress Syndrome. Terminated NCT00767039 Phase 4 Survanta (beractant);Curosurf (poractant)
27 Effects of the Use of a Bottle and a Cup on Breast Sucking Patterns of Premature Infants: Safety and Efficacy Terminated NCT00703950 Phase 4
28 Incidence and Severity of Parenteral Nutrition Associated Cholestasis in Neonates Subjected to Major Surgery, Using Two Mixed Intravenous Lipid Emulsions Terminated NCT02633384 Phase 4
29 Randomized Trial on Efficacy and Safety of the Antenatal Rescue Course of Glucocorticoids in Threatened Premature Birth (ACG Trial) Terminated NCT00295464 Phase 4 Betamethasone sodium phos (drug)
30 Addition of a Probiotic (Lactobacillus GG) to Metronidazole for the Treatment of Clostridium Difficile Associated Disease Withdrawn NCT00304863 Phase 4 Lactobacillus GG
31 A Pilot Study to Compare the Use of Fresh Frozen Plasma With 24-Hour Plasma in Babies Up to Age Six Months Withdrawn NCT02774317 Phase 4
32 A Randomised Controlled Trial Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus In Very Premature Infants Withdrawn NCT00470743 Phase 4 Ibuprofen;Indomethacin
33 Role Of Saccharomyces Boulardii in Preventin Necrotizing Enterocolitis in Very Low Birth Weight Infants Unknown status NCT01315821 Phase 3 Saccharomyces boulardii;Placebo
34 Efficacy and Safety of Probiotics in Neonatal Hyperbilirubinemia Unknown status NCT03266913 Phase 3 Probiotic
35 Paracetamol Versus Ibuprofen for Patent Ductus Arteriosus Closure in Preterm Infants. A Prospective, Randomized, Controlled, Double Blind, Multicenter Clinical Trial. Unknown status NCT02056223 Phase 2, Phase 3 Intravenous paracetamol;Intravenous ibuprofen
36 Nasal Intermittent Mandatory Ventilation Versus Continuous Positive Airway Pressure After Extubation of Very Low Birth Weight Infants of the NEOCOSUR Network. Unknown status NCT01778829 Phase 3
37 Evaluation of the Role of Vaginal Progesterone in Prevention of Preterm Labor in Twin Gestation With Short Cervix: Randomised Controlled Trial Unknown status NCT02697331 Phase 3 Progesterone
38 Effect of Cysteine Supplementation on Glutathione Production in Critically Ill Neonates Unknown status NCT00254176 Phase 2, Phase 3
39 Role Of Lactobacillus Reuteri in Preventing Necrotizing Enterocolitis in Very Low Birth Weight Infants Completed NCT01531179 Phase 3 Lactobacillus reuteri;Placebo
40 A Randomized, Double-Blind Study of GT267-004 Versus Vancomycin, and GT267-004 Versus Metronidazole, in Patients With C.Difficile - Associated Diarrhea Completed NCT00106509 Phase 3 tolevamer potassium-sodium (GT267-004)
41 A Randomized, Double-Blind Study of GT267-004 Versus Vancomycin, and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associated Diarrhea Completed NCT00196794 Phase 3 Tolevamer potassium-sodium (GT267-004)
42 The Efficacy of Symbiotic Preparation on Cytokines Which Act on Necrotising Enterocolitis Pathogenesis in Very Low Birth Weight Infants Completed NCT01899677 Phase 3 symbiotic
43 Role of Probiotics for Prevention of Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants: A Double Blind Randomized Controlled Trial Completed NCT02650869 Phase 3
44 Effect of Vitamin A in the Treatment of Sepsis and Necrotizing Enterocolitis in Hospitalized Neonates Completed NCT00707785 Phase 3
45 Nosocomial Infections and Necrotizing Enterocolitis in Preterm Neonates Treated With Lactobacillus Acidophilus and Bifidobacterium Infantis in An Intensive Care Unit : A Randomized Controlled Study Completed NCT01340469 Phase 3
46 Prospective, Randomized Study of Oral Metronidazole vs. Oral Metronidazole and Rifampin for Treatment of Clostridium Difficile-associated Diarrhea (CDAD) Completed NCT00182429 Phase 3 Metronidazole and Rifampin
47 Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP) Completed NCT00009646 Phase 3 indomethacin;Indomethacin;Placebo
48 Compassionate Use of Nitazoxanide for the Treatment of Clostridium Difficile Colitis in Patients Who Have Failed Conventional Therapy Completed NCT00304356 Phase 3 Nitazoxanide
49 The Use of Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature and Very-low Birth Weight Infants Completed NCT01868737 Phase 3
50 Progesterone Vaginal Pessary for Prevention of Preterm Twin Birth Completed NCT02350231 Phase 2, Phase 3 The progesterone vaginal pessary;Tonics group

Search NIH Clinical Center for Enterocolitis

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Clidinium
Hyoscyamine

Genetic Tests for Enterocolitis

Genetic tests related to Enterocolitis:

# Genetic test Affiliating Genes
1 Enterocolitis 29

Anatomical Context for Enterocolitis

MalaCards organs/tissues related to Enterocolitis:

41
Colon, Breast, Heart, Lung, Small Intestine, Liver, Brain

Publications for Enterocolitis

Articles related to Enterocolitis:

(show top 50) (show all 11063)
# Title Authors PMID Year
1
Early lethal autosomal recessive enterocolitis: report of a second family. 38 8
17204052 2007
2
A lethal autosomal recessive entero-colitis of early infancy. 8
4426135 1974
3
[Gastrointestinal abnormalities in children with autism]. 9 38
19650428 2009
4
Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. 9 38
16710025 2006
5
Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer. 9 38
16224277 2005
6
A human yeast artificial chromosome containing the multiple endocrine neoplasia type 2B Ret mutation does not induce medullary thyroid carcinoma but does support the growth of kidneys and partially rescues enteric nervous system development in Ret-deficient mice. 9 38
15632018 2005
7
Inflammatory changes secondary to postoperative complications of Hirschsprung's disease as a cause of histopathologic changes typical of intestinal neuronal dysplasia. 9 38
14966730 2004
8
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. 9 38
12826605 2003
9
Piperacillin/tazobactam in comparison with clindamycin plus gentamicin in the treatment of intra-abdominal infections. 9 38
7553416 1995
10
Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen. 9 38
7532192 1995
11
Food protein-induced enterocolitis to casein hydrolysate formulas. 9 38
8258625 1993
12
Efficacy and safety of oral paracetamol versus oral ibuprofen for closure of patent ductus arteriosus in preterm infants: a randomized controlled trial. 38
29695206 2019
13
Acute kidney injury in preterm infants with necrotizing enterocolitis. 38
29631454 2019
14
Does fortification of pasteurized donor human milk increase the incidence of necrotizing enterocolitis among preterm neonates? A randomized controlled trial. 38
29618272 2019
15
Survival rates for surgically treated necrotising enterocolitis have improved over the last four decades. 38
30825252 2019
16
Prophylactic use of probiotics for gastrointestinal disorders in children. 38
31279590 2019
17
Noninvasive Ventilation in the Age of Surfactant Administration. 38
31345543 2019
18
Species identification and molecular characterization of Cronobacter spp. isolated from food imported over nine years into Beijing, China. 38
31027763 2019
19
Epidemiology and healthcare factors associated with neonatal enterococcal infections. 38
30425112 2019
20
Achieved Oxygenation Saturations and Outcome in Extremely Preterm Infants. 38
31345550 2019
21
Altered expression of caveolin-1 in the colon of patients with Hirschsprung's disease. 38
31256294 2019
22
Meta-analysis of Oxygenation Saturation Targeting Trials: Do Infant Subgroups Matter? 38
31345548 2019
23
Early versus delayed umbilical cord clamping on maternal and neonatal outcomes. 38
31203386 2019
24
Abdominal ultrasound should become part of standard care for early diagnosis and management of necrotising enterocolitis: a narrative review. 38
31079066 2019
25
Thrombosis after umbilical venous catheterisation: prospective study with serial ultrasound. 38
31391204 2019
26
Primary, secondary, and tertiary preventions of preterm birth with cervical cerclage. 38
31056734 2019
27
Donkey's Milk in the Management of Children with Cow's Milk protein allergy: nutritional and hygienic aspects. 38
31420060 2019
28
Toll Like Receptor 4 Mediated Lymphocyte Imbalance Induces Nec-Induced Lung Injury. 38
30148762 2019
29
The Inadequate Oxygen Delivery Index and Low Cardiac Output Syndrome Score As Predictors of Adverse Events Associated With Low Cardiac Output Syndrome Early After Cardiac Bypass. 38
31033863 2019
30
[Effect of different feeding initiation formulas on very low birth weight infants]. 38
31416502 2019
31
Inhibition of HMGB1 improves necrotizing enterocolitis by inhibiting NLRP3 via TLR4 and NF-κB signaling pathways. 38
30618088 2019
32
Regulation of ROS-NF-κB axis by tuna backbone derived peptide ameliorates inflammation in necrotizing enterocolitis. 38
30656693 2019
33
Innate immune activation occurs in acute food protein-induced enterocolitis syndrome reactions. 38
31059725 2019
34
Ghrelin ameliorates the phenotype of newborn rats induced with mild necrotizing enterocolitis. 38
31386261 2019
35
Early diagnosis of necrotizing enterocolitis by plasma RELMβ and thrombocytopenia in preterm infants: A pilot study. 38
30799148 2019
36
A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions. 38
31375667 2019
37
Clostridium difficile Enterocolitis in a Captive Geoffroy's Spider Monkey (Ateles geoffroyi) and Common Marmosets (Callithrix jacchus). 38
31382854 2019
38
A modified oral food challenge in children with food protein induced enterocolitis syndrome. 38
31386243 2019
39
The MicroRNA Landscapes Profiling Reveals Potential Signatures of Necrotizing Enterocolitis in Infants. 38
31390270 2019
40
Remission Patterns of Food Protein-Induced Enterocolitis Syndrome in a Greek Pediatric Population. 38
31390649 2019
41
Relationship of Necrotizing Enterocolitis Rates to Adoption of Prevention Practices in US Neonatal Intensive Care Units. 38
30893097 2019
42
Historical aspects of probiotic use to prevent necrotising enterocolitis in preterm babies. 38
31153726 2019
43
Necrotizing Enterocolitis: State of the Art in Translating Experimental Research to the Bedside. 38
31426115 2019
44
The relation between serum levels of epidermal growth factor and necrotizing enterocolitis in preterm neonates. 38
30999731 2019
45
Probiotic strategies to prevent necrotizing enterocolitis in preterm infants: a meta-analysis. 38
31420743 2019
46
Escherichia coli O157 Enterocolitis Followed by Non-diarrheagenic Escherichia coli Bacteremia. 38
30838530 2019
47
Mother's Touch: Milk IgA and Protection from Necrotizing Enterocolitis. 38
31415742 2019
48
Probiotic mechanisms of action. 38
31174927 2019
49
The role of fecal calprotectin in pediatric disease. 38
30999729 2019
50
Investigation of a Yersinia enterocolitica outbreak in a commercial alpaca farm in Saskatchewan. 38
31391607 2019

Variations for Enterocolitis

Expression for Enterocolitis

Search GEO for disease gene expression data for Enterocolitis.

Pathways for Enterocolitis

Pathways related to Enterocolitis according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.65 TLR4 NLRC4 CXCL8 CFHR3 CFH CFB
2
Show member pathways
12.73 TLR4 NLRC4 CXCL8 C3
3 11.77 CFH CFB CD46 C3
4
Show member pathways
11.58 CFH CFB CD46 C3
5 11.53 CFH CFB C3
6 11.52 TLR4 NLRC4 CXCL8
7
Show member pathways
11.52 CFHR3 CFH CFB CD46 C3
8 11.46 TLR4 CXCL8 C3
9 11.2 TLR4 NLRC4 CXCL8 C3
10 11.17 TLR4 CXCL8
11
Show member pathways
11.15 CFHR3 CFH CFB CD46 C3

GO Terms for Enterocolitis

Cellular components related to Enterocolitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 CXCL8 CFHR3 CFHR1 CFH CFB C3
2 blood microparticle GO:0072562 9.02 CFHR3 CFHR1 CFH CFB C3

Biological processes related to Enterocolitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.73 TLR4 NLRC4 CXCL8 C3
2 immune system process GO:0002376 9.72 TLR4 NLRC4 CFB CD46 C3
3 innate immune response GO:0045087 9.63 TLR4 NLRC4 CFH CFB CD46 C3
4 complement activation GO:0006956 9.56 CFHR1 CFH CFB C3
5 positive regulation of interleukin-10 production GO:0032733 9.48 TLR4 CD46
6 activation of innate immune response GO:0002218 9.46 TLR4 NLRC4
7 positive regulation of cytolysis GO:0045919 9.4 CFHR5 CFHR1
8 interleukin-1 beta secretion GO:0050702 9.37 TLR4 NLRC4
9 complement activation, alternative pathway GO:0006957 9.26 CFHR5 CFH CFB C3
10 regulation of complement activation GO:0030449 9.1 CFHR5 CFHR1 CFH CFB CD46 C3

Sources for Enterocolitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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