MCID: ENT011
MIFTS: 50

Enterocolitis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Enterocolitis

MalaCards integrated aliases for Enterocolitis:

Name: Enterocolitis 56 29 54 17 71

Characteristics:

OMIM:

56
Inheritance:
autosomal recessive


HPO:

31
enterocolitis:
Inheritance autosomal recessive inheritance


Classifications:



External Ids:

OMIM 56 226150
ICD10 32 A04.7
MedGen 41 C0014356
UMLS 71 C0014356

Summaries for Enterocolitis

MalaCards based summary : Enterocolitis is related to perinatal necrotizing enterocolitis and diarrhea. An important gene associated with Enterocolitis is NLRC4 (NLR Family CARD Domain Containing 4), and among its related pathways/superpathways are Innate Immune System and Shigellosis. The drugs Ceftriaxone and Adalimumab have been mentioned in the context of this disorder. Affiliated tissues include colon, heart and breast, and related phenotypes are hematochezia and abdominal distention

Wikipedia : 74 Enterocolitis is an inflammation of the digestive tract, involving enteritis of the small intestine and... more...

More information from OMIM: 226150

Related Diseases for Enterocolitis

Diseases related to Enterocolitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 614)
# Related Disease Score Top Affiliating Genes
1 perinatal necrotizing enterocolitis 34.6 TLR4 FABP2 CXCL8
2 diarrhea 31.0 TLR4 CXCL8 CD46 C3
3 celiac disease 1 30.1 TLR4 FABP2 CXCL8
4 necrotizing fasciitis 30.1 CXCL8 CD46
5 pouchitis 30.1 TLR4 CXCL8
6 shigellosis 30.0 TLR4 NLRC4 CXCL8
7 bronchopneumonia 29.9 TLR4 CXCL8
8 pertussis 29.9 TLR4 CXCL8 C3
9 capillary leak syndrome 29.8 CXCL8 C3
10 otitis media 29.7 TLR4 CXCL8 C3
11 neisseria meningitidis infection 29.6 TLR4 CD46 C3
12 severe pre-eclampsia 29.6 CFH CFB C3
13 complement component 2 deficiency 29.6 CFH CFB
14 histoplasmosis 29.5 CFH C3
15 meningitis 29.3 TLR4 CXCL8 CFI CD46 C3
16 hemolytic uremic syndrome, atypical 1 28.6 CFI CFHR5 CFHR3 CFHR1 CFH CFB
17 hemolytic anemia 28.3 CFI CFHR1 CFH CFB CD46 C3
18 systemic lupus erythematosus 28.0 TLR4 CXCL8 CFI CFH CFB CD46
19 hemolytic-uremic syndrome 26.6 CXCL8 CFI CFHR5 CFHR3 CFHR1 CFH
20 thrombocytopenia 26.5 TLR4 CXCL8 CFI CFHR5 CFHR3 CFHR1
21 autoinflammation with infantile enterocolitis 12.8
22 mastocytic enterocolitis 12.6
23 clostridium difficile colitis 11.9
24 short bowel syndrome 11.7
25 hirschsprung disease 1 11.6
26 inflammatory bowel disease 11.5
27 patent ductus arteriosus 1 11.5
28 hypoganglionosis 11.5
29 5-oxoprolinase deficiency 11.1
30 pigmentary disorder, reticulate, with systemic manifestations, x-linked 11.1
31 hemolytic uremic syndrome, atypical 2 11.1
32 hemolytic uremic syndrome, atypical 3 11.1
33 hemolytic uremic syndrome, atypical 4 11.1
34 hemolytic uremic syndrome, atypical 5 11.1
35 hemolytic uremic syndrome, atypical 6 11.1
36 intestinal perforation 10.7
37 neutropenia 10.6
38 food allergy 10.6
39 peritonitis 10.6
40 crohn's disease 10.5
41 colitis 10.5
42 intestinal disease 10.5
43 gastroenteritis 10.4
44 intestinal obstruction 10.4
45 ileus 10.4
46 overgrowth syndrome 10.4
47 ulcerative colitis 10.4
48 acute leukemia 10.4
49 appendicitis 10.4
50 chlamydia pneumonia 10.4 TLR4 CXCL8

Graphical network of the top 20 diseases related to Enterocolitis:



Diseases related to Enterocolitis

Symptoms & Phenotypes for Enterocolitis

Human phenotypes related to Enterocolitis:

31
# Description HPO Frequency HPO Source Accession
1 hematochezia 31 HP:0002573
2 abdominal distention 31 HP:0003270
3 ulcerative colitis 31 HP:0100279
4 enterocolitis 31 HP:0004387

Symptoms via clinical synopsis from OMIM:

56
G I:
ulcerative colitis
bloody diarrhea
pseudomembranous enterocolitis

Abdomen:
swelling

Clinical features from OMIM:

226150

MGI Mouse Phenotypes related to Enterocolitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.1 C3 CFB CFH CFI FABP2 TLR4

Drugs & Therapeutics for Enterocolitis

Drugs for Enterocolitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 241)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
2
Adalimumab Approved Phase 4 331731-18-1 16219006
3
Fidaxomicin Approved Phase 4 873857-62-6
4
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
5
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
6
Histamine Approved, Investigational Phase 4 51-45-6 774
7
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
8
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
9
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
10
Zinc Approved, Investigational Phase 4 7440-66-6 32051
11
Zinc sulfate Approved, Investigational Phase 4 7733-02-0
12
Tocopherol Approved, Investigational Phase 4 1406-66-2, 54-28-4 14986
13 Poractant alfa Approved Phase 4 129069-19-8
14
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
15 Beractant Approved Phase 4 108778-82-1
16
Sorbitol Approved Phase 4 50-70-4 5780
17 Coconut Approved Phase 4
18
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
19
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
20
Beta carotene Approved, Nutraceutical Phase 4 7235-40-7
21
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 6221 5280795
22
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
23 Tocotrienol Investigational Phase 4 6829-55-6
24 Immunoglobulins Phase 4
25 Antibodies Phase 4
26 Immunologic Factors Phase 4
27 Immunoglobulins, Intravenous Phase 4
28 Rho(D) Immune Globulin Phase 4
29 gamma-Globulins Phase 4
30 Antioxidants Phase 4
31 Protective Agents Phase 4
32 Antibiotics, Antitubercular Phase 4
33 Antitubercular Agents Phase 4
34 Carotenoids Phase 4
35 Antiemetics Phase 4
36 BB 1101 Phase 4
37 Ergocalciferols Phase 4
38 Antineoplastic Agents, Hormonal Phase 4
39 Calciferol Phase 4
40
Picolinic acid Phase 4 98-98-6 1018
41 Provitamins Phase 4
42 Vitamin D2 Phase 4
43 Anti-Ulcer Agents Phase 4
44 Bismuth tripotassium dicitrate Phase 4
45 Histamine H2 Antagonists Phase 4
46
Histamine Phosphate Phase 4 51-74-1 65513
47 Histamine Antagonists Phase 4
48
Bismuth Phase 4 7440-69-9 16682734 105143
49 Ranitidine bismuth citrate Phase 4
50 Antacids Phase 4

Interventional clinical trials:

(show top 50) (show all 420)
# Name Status NCT ID Phase Drugs
1 The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis Unknown status NCT01278017 Phase 4 ceftriaxone
2 The Effect of Withholding Feeds During Red Blood Cell Transfusion on Development of TRAGI in Very Low Birth Weight Infants Unknown status NCT02132819 Phase 4
3 The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation (Crohn's Disease) and Markers of Inflammation Unknown status NCT01765998 Phase 4 Probiotic;Placebo
4 THE EFFECT OF SUSTAINED LUNG INFLATION MANEUVER APPLIED THROUGH NASAL PRONG ON EARLY AND LATE RESPIRATORY MORBIDITIES IN PRETERM INFANTS Unknown status NCT02887924 Phase 4
5 Gut-kidney Axis: Renal Effects of Meditarranean Diet and Low-protein Diet With Ketoacids to Restore Physiological Intestinal Mibrobiota in Chronic Kidney Disease Unknown status NCT02302287 Phase 4
6 Postmarketing Study of Probiotics Medication in Childhood Diarrhea Completed NCT00463190 Phase 4 Biothree
7 Systematic Randomized , Single Blinded, Placebo-Controlled Trial of Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis Completed NCT02959229 Phase 4 Lactoferrin;Placebo (for Lactoferrin)
8 A Randomized Trial to Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates in Developing Countries Completed NCT01403623 Phase 4
9 Randomized Evaluation of the Use of Plastic Bags to Prevent Neonatal Hypothermia in Developing Countries-Part IV Completed NCT01604447 Phase 4
10 A Randomized Double-Blinded Study Comparing the Impact of One Versus Two Courses of Antenatal Steroids on Neonatal Outcome Completed NCT00201643 Phase 4 Betamethasone or Dexamethasone (2nd course of ACS);Placebo
11 Intestinal Inflammation in Ankylosing Spondylitis Assessed by Fecal Calprotectin, Capsular Endoscopy and Colonoscopy and the Effects of Adalimumab on Mucosal Healing Completed NCT01174186 Phase 4 Adalimumab
12 Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory Distress Completed NCT00486850 Phase 4
13 Exploratory Study of Impact of Oral Metronidazole, Vancomycin and Fidaxomicin on the Extent and Quantity of Host Carriage and Environmental Contamination With C. Difficile Completed NCT02057198 Phase 4 Fidaxomicin;Metronidazole;Vancomycin
14 Phase 4 Study of Use of High-dose Intravenous Immune Globulin for Prevent Hyperbilirubinemia Due Rh Hemolytic Disease in Newborns Infants Completed NCT00288600 Phase 4 Intravenous Immunoglobulin;Normal saline solution
15 Probiotics for Prophylaxis of Postoperative Hirschsprungs Associated Enterocolitis Recruiting NCT02343562 Phase 4
16 The Effect of Co-administered β-Carotene, Vitamin D3, Zinc and Antenatal Steroid Therapy on Hyaline Membrane Disease and Feeding Intolerance in Premature Neonates Recruiting NCT03366584 Phase 4 Dexamethasone
17 Early Sodium Intake in Preterm Newborns; Randomized Clinical Trial Recruiting NCT04035564 Phase 4 Sodium < 1mEq/kg/day;Sodium 5mEq/kg/day
18 Stress Ulcer Prophylaxis Versus Placebo - a Blinded Randomized Control Trial to Evaluate the Safety of Two Strategies in Critically Ill Infants With Congenital Heart Disease Recruiting NCT03667703 Phase 4 Ranitidine;Placebo
19 Multicentre Randomised Controlled Trial of Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on Continuous Positive Airways Pressure Recruiting NCT02140580 Phase 4
20 Effect of Lactobacillus Reuteri DSM 17938 to Prevent Antibiotic-associated Diarrhea in Children: Prospective, Multi-center, Randomize, Parallel Group Placebo Controlled Clinical Trial Recruiting NCT02765217 Phase 4 Lactobacillus reuteri DSM 17938;Placebo;Amoxicillin-Clavulanic Acid
21 Oral Zinc Supplementation Improving Growth and Reducing Morbidity on Very Low Birth Weight Infant Not yet recruiting NCT04050488 Phase 4 Zinc Sulfate;Placebos
22 NICU Antibiotics and Outcomes Trial Not yet recruiting NCT03997266 Phase 4 Ampicillin;Gentamycin;Normal saline
23 Personalized Versus Standardized Parenteral Nutrition for Preterm Infants With a Birth Weight Greater Than 1250 Grams: a Multicenter Randomized Phase IV Clinical Trial Not yet recruiting NCT03693287 Phase 4 Standardized-parenteral nutrition (S-PN);Personalized-parenteral nutrition (P-PN)
24 The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study Terminated NCT00164099 Phase 4 Synbiotic 2000
25 Impact of Early Postnatal Sodium Supplementation on Weight Gain in Very Low Birth Weight Infants Terminated NCT01795638 Phase 4 Sodium chloride;Placebo
26 Phase 4 Study of Curosurf (Poractant) and Survanta (Beractant) Surfactant Treatment in Very Premature Infants With Respiratory Distress Syndrome. Terminated NCT00767039 Phase 4 Survanta (beractant);Curosurf (poractant)
27 Effects of the Use of a Bottle and a Cup on Breast Sucking Patterns of Premature Infants: Safety and Efficacy Terminated NCT00703950 Phase 4
28 Incidence and Severity of Parenteral Nutrition Associated Cholestasis in Neonates Subjected to Major Surgery, Using Two Mixed Intravenous Lipid Emulsions Terminated NCT02633384 Phase 4
29 Randomized Trial on Efficacy and Safety of the Antenatal Rescue Course of Glucocorticoids in Threatened Premature Birth (ACG Trial) Terminated NCT00295464 Phase 4 Betamethasone sodium phos (drug)
30 Addition of a Probiotic (Lactobacillus GG) to Metronidazole for the Treatment of Clostridium Difficile Associated Disease Withdrawn NCT00304863 Phase 4 Lactobacillus GG
31 A Pilot Study to Compare the Use of Fresh Frozen Plasma With 24-Hour Plasma in Babies Up to Age Six Months Withdrawn NCT02774317 Phase 4
32 A Randomised Controlled Trial Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus In Very Premature Infants Withdrawn NCT00470743 Phase 4 Ibuprofen;Indomethacin
33 Role Of Saccharomyces Boulardii in Preventin Necrotizing Enterocolitis in Very Low Birth Weight Infants Unknown status NCT01315821 Phase 3 Saccharomyces boulardii;Placebo
34 Efficacy and Safety of Probiotics in Neonatal Hyperbilirubinemia Unknown status NCT03266913 Phase 3 Probiotic
35 Nasal Intermittent Mandatory Ventilation Versus Continuous Positive Airway Pressure After Extubation of Very Low Birth Weight Infants of the NEOCOSUR Network. Unknown status NCT01778829 Phase 3
36 Evaluation of the Role of Vaginal Progesterone in Prevention of Preterm Labor in Twin Gestation With Short Cervix: Randomised Controlled Trial Unknown status NCT02697331 Phase 3 Progesterone
37 Effect of Cysteine Supplementation on Glutathione Production in Critically Ill Neonates Unknown status NCT00254176 Phase 2, Phase 3
38 Role Of Lactobacillus Reuteri in Preventing Necrotizing Enterocolitis in Very Low Birth Weight Infants Completed NCT01531179 Phase 3 Lactobacillus reuteri;Placebo
39 A Randomized, Double-Blind Study of GT267-004 Versus Vancomycin, and GT267-004 Versus Metronidazole, in Patients With C.Difficile - Associated Diarrhea Completed NCT00106509 Phase 3 tolevamer potassium-sodium (GT267-004)
40 A Randomized, Double-Blind Study of GT267-004 Versus Vancomycin, and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associated Diarrhea Completed NCT00196794 Phase 3 Tolevamer potassium-sodium (GT267-004)
41 The Efficacy of Symbiotic Preparation on Cytokines Which Act on Necrotising Enterocolitis Pathogenesis in Very Low Birth Weight Infants Completed NCT01899677 Phase 3 symbiotic
42 Role of Probiotics for Prevention of Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants: A Double Blind Randomized Controlled Trial Completed NCT02650869 Phase 3
43 Effect of Vitamin A in the Treatment of Sepsis and Necrotizing Enterocolitis in Hospitalized Neonates Completed NCT00707785 Phase 3
44 Nosocomial Infections and Necrotizing Enterocolitis in Preterm Neonates Treated With Lactobacillus Acidophilus and Bifidobacterium Infantis in An Intensive Care Unit : A Randomized Controlled Study Completed NCT01340469 Phase 3
45 Prospective, Randomized Study of Oral Metronidazole vs. Oral Metronidazole and Rifampin for Treatment of Clostridium Difficile-associated Diarrhea (CDAD) Completed NCT00182429 Phase 3 Metronidazole and Rifampin
46 Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP) Completed NCT00009646 Phase 3 indomethacin;Indomethacin;Placebo
47 A Prospective, Multi-center, Randomized Trial of Fecal Microbiota Transplantation (FMT) Delivered by Capsule vs Colonoscopy in the Management of Recurrent Clostridium Difficile Infection (CDI) Completed NCT02254811 Phase 2, Phase 3
48 Compassionate Use of Nitazoxanide for the Treatment of Clostridium Difficile Colitis in Patients Who Have Failed Conventional Therapy Completed NCT00304356 Phase 3 Nitazoxanide
49 The Use of Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature and Very-low Birth Weight Infants Completed NCT01868737 Phase 3
50 Progesterone Vaginal Pessary for Prevention of Preterm Twin Birth Completed NCT02350231 Phase 2, Phase 3 The progesterone vaginal pessary;Tonics group

Search NIH Clinical Center for Enterocolitis

Genetic Tests for Enterocolitis

Genetic tests related to Enterocolitis:

# Genetic test Affiliating Genes
1 Enterocolitis 29

Anatomical Context for Enterocolitis

MalaCards organs/tissues related to Enterocolitis:

40
Colon, Heart, Breast, Lung, Liver, Small Intestine, Brain

Publications for Enterocolitis

Articles related to Enterocolitis:

(show top 50) (show all 11356)
# Title Authors PMID Year
1
Early lethal autosomal recessive enterocolitis: report of a second family. 61 56
17204052 2007
2
A lethal autosomal recessive entero-colitis of early infancy. 56
4426135 1974
3
[Gastrointestinal abnormalities in children with autism]. 54 61
19650428 2009
4
Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. 54 61
16710025 2006
5
Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer. 54 61
16224277 2005
6
A human yeast artificial chromosome containing the multiple endocrine neoplasia type 2B Ret mutation does not induce medullary thyroid carcinoma but does support the growth of kidneys and partially rescues enteric nervous system development in Ret-deficient mice. 54 61
15632018 2005
7
Inflammatory changes secondary to postoperative complications of Hirschsprung's disease as a cause of histopathologic changes typical of intestinal neuronal dysplasia. 54 61
14966730 2004
8
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. 54 61
12826605 2003
9
Piperacillin/tazobactam in comparison with clindamycin plus gentamicin in the treatment of intra-abdominal infections. 54 61
7553416 1995
10
Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen. 54 61
7532192 1995
11
Food protein-induced enterocolitis to casein hydrolysate formulas. 54 61
8258625 1993
12
A Pharmacoepidemiologic Study of the Safety and Effectiveness of Clindamycin in Infants. 61
31725114 2020
13
Characterization of Circulating Clostridium difficile Strains, Host Response and Intestinal Microbiome in Hospitalized Children With Diarrhea. 61
31876614 2020
14
When is parenteral nutrition indicated in the hospitalized, acutely ill patient? 61
31895227 2020
15
Fulminant Necrotizing Enterocolitis and Multiple Organ Dysfunction in a Toddler with Mitochondrial DNA Depletion Syndrome-13. 61
31984159 2020
16
Changes of intestinal microbiota in early life. 61
30058404 2020
17
Neutropenic Enterocolitis: Clinical Features and Outcomes. 61
31842164 2020
18
The protective effects of sesamol in a neonatal rat model of necrotizing enterocolitis. 61
30058400 2020
19
Totally robotic soave pull-through procedure for Hirschsprung's disease: lessons learned from 11 consecutive pediatric patients. 61
31659436 2020
20
Physical Activity and Spatial Memory Are Minimally Affected by Moderate Growth Restriction in Preterm Piglets. 61
32015235 2020
21
Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC-3G3) to patients with advanced soft tissue sarcoma. 61
31821732 2020
22
Cytokine responses to symbiotic and lactoferrin combination in very low birth weight neonates: a randomized control trial. 61
31984696 2020
23
Fatal intestinal inflammatory lesions in equids in California: 710 cases (1990-2013). 61
31999521 2020
24
Human breast milk exosomes attenuate intestinal damage. 61
31713717 2020
25
Clostridium Difficile infections in patients with AML or MDS undergoing allogeneic hematopoietic stem cell transplantation identify high risk for adverse outcome. 61
31534193 2020
26
Maternal and perinatal outcomes and factors associated with twin pregnancies among preterm births: Evidence from the Brazilian Multicenter Study on Preterm Birth (EMIP). 61
32012259 2020
27
Parenteral Nutrition in Moderately Preterm, Otherwise Healthy Neonates Is Not Associated With Improved Short-Term Growth Outcomes. 61
32026496 2020
28
Use of pediatric donor en bloc kidneys along with bladder segment in pediatric liver-kidney and multivisceral-kidney transplantation. 61
31605438 2020
29
CTX-M-15 Producing Escherichia coli Sequence Type 361 and Sequence Type 38 Causing Bacteremia and Umbilical Infection in a Neonate Foal. 61
31952646 2020
30
Necrotizing Enterocolitis: A Multi-omic Approach and the Role of the Microbiome. 61
32008132 2020
31
How to use abdominal X-rays in preterm infants suspected of developing necrotising enterocolitis. 61
30777865 2020
32
Epidermal Growth Factor (EGF) as reliable marker in necrotizing enterocolitis in preterm neonates. 61
32024341 2020
33
Characteristics and incidence of transfusion-associated necrotizing enterocolitis in the UK. 61
29945481 2020
34
Preterm infant gut microbial patterns related to the development of necrotizing enterocolitis. 61
29909714 2020
35
Red blood cell transfusion and short-term outcomes in very low birth weight infants. 61
32024329 2020
36
Short-term and long-term outcomes of very-low-birth-weight infants in Korea: Korean Neonatal Network update in 2019. 61
32023404 2020
37
Neurocognitive Functioning in Early School-age Children With Intestinal Failure. 61
31978022 2020
38
Reduced fetal movements is twin pregnancies and the association with adverse neonatal outcomes. 61
32032929 2020
39
Effects of antenatal indomethacin on ductus arteriosus early closure and on adverse outcomes in preterm neonates. 61
29986620 2020
40
The association of pregestational and gestational diabetes with severe neonatal morbidity and mortality. 61
31591489 2020
41
The effects of proton pump inhibitors on the microbiome in young children. 61
32027402 2020
42
Quality of probiotic products for preterm infants: Contamination and missing strains. 61
31423636 2020
43
Febrile Neutropenia in a Patient with Non-Small Cell Lung Cancer Treated with the Immune-Checkpoint Inhibitor Nivolumab. 61
32018275 2020
44
The Role of Gastrointestinal-Related Fatty Acid-Binding Proteins as Biomarkers in Gastrointestinal Diseases. 61
31529416 2020
45
Profile analysis reveals endogenous RNAs regulate necrotizing enterocolitis progression. 61
32036223 2020
46
Synbiotic use for the prevention of sepsis and necrotizing enterocolitis in very low birth weight neonates: a randomized controlled trial. 61
32023397 2020
47
Cost-effectiveness Analysis of Feeding Guidelines for Infants Following Intestinal Surgery. 61
31977952 2020
48
Prolonged minimal enteral nutrition versus early feeding advancements in preterm infants with birth weight ≤1250 g: a prospective randomized trial. 61
31994953 2020
49
Bilateral Pulmonary Artery Banding before Norwood Procedure: Survival of High-Risk Patients. 61
30609447 2020
50
Extremely Preterm Infants Have Significant Alterations in Their Conventional T Cell Compartment during the First Weeks of Life. 61
31801814 2020

Variations for Enterocolitis

Expression for Enterocolitis

Search GEO for disease gene expression data for Enterocolitis.

Pathways for Enterocolitis

Pathways related to Enterocolitis according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.7 TLR4 NLRC4 CXCL8 CFI CFHR3 CFH
2 12.08 TLR4 NLRC4 CXCL8 C3
3 11.93 TLR4 NLRC4 CXCL8
4
Show member pathways
11.79 CFI CFHR3 CFH CFB CD46 C3
5
Show member pathways
11.69 CFH CFB CD46 C3
6 11.6 CFI CFH CFB C3
7 11.56 TLR4 NLRC4 CXCL8
8
Show member pathways
11.56 CFI CFHR3 CFH CFB CD46 C3
9 11.49 TLR4 CXCL8 C3
10 11.39 CFI CFHR5 CFHR3 CFHR1 CFH CFB
11 11.31 TLR4 NLRC4 CXCL8 C3

GO Terms for Enterocolitis

Cellular components related to Enterocolitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 CXCL8 CFI CFHR5 CFHR1 CFH CFB
2 extracellular space GO:0005615 9.5 CXCL8 CFI CFHR3 CFHR1 CFH CFB
3 blood microparticle GO:0072562 9.02 CFHR3 CFHR1 CFH CFB C3

Biological processes related to Enterocolitis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.77 TLR4 NLRC4 CFB CD46 C3
2 inflammatory response GO:0006954 9.73 TLR4 NLRC4 CXCL8 C3
3 innate immune response GO:0045087 9.7 TLR4 NLRC4 CFI CFH CFB CD46
4 complement activation, classical pathway GO:0006958 9.63 CFI CD46 C3
5 complement activation GO:0006956 9.56 CFHR1 CFH CFB C3
6 activation of innate immune response GO:0002218 9.49 TLR4 NLRC4
7 positive regulation of interleukin-10 production GO:0032733 9.48 TLR4 CD46
8 interleukin-1 beta secretion GO:0050702 9.4 TLR4 NLRC4
9 positive regulation of cytolysis GO:0045919 9.32 CFHR5 CFHR1
10 complement activation, alternative pathway GO:0006957 9.26 CFHR5 CFH CFB C3
11 regulation of complement activation GO:0030449 9.17 CFI CFHR5 CFHR1 CFH CFB CD46

Sources for Enterocolitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....