Aliases & Classifications for Entropion

MalaCards integrated aliases for Entropion:

Name: Entropion 12 6 45 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:12397
ICD9CM 36 374.00
MeSH 45 D004774
SNOMED-CT 69 33168009
UMLS 74 C0014390

Summaries for Entropion

MalaCards based summary : Entropion is related to senile entropion and cicatricial entropion, and has symptoms including erythema of the eyelids An important gene associated with Entropion is MYO3B (Myosin IIIB). The drugs Ketamine and Desflurane have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and testes.

Wikipedia : 77 Entropion is a medical condition in which the eyelid (usually the lower lid) folds inward. It is very... more...

Related Diseases for Entropion

Diseases related to Entropion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Related Disease Score Top Affiliating Genes
1 senile entropion 12.4
2 cicatricial entropion 12.3
3 spastic entropion 12.3
4 mechanical entropion 12.2
5 isolated congenital entropion 12.1
6 wiedemann-rautenstrauch syndrome 11.2
7 pyramidal molars-abnormal upper lip syndrome 11.2
8 ectropion 10.7
9 trachoma 10.4
10 epiblepharon 10.4
11 senile ectropion 10.3
12 ocular cicatricial pemphigoid 10.3
13 ptosis 10.2
14 cicatricial pemphigoid 10.2
15 cutis laxa 10.1
16 distichiasis 10.0
17 severe cutaneous adverse reaction 10.0
18 cataract 10.0
19 blepharospasm 10.0
20 corneal ulcer 10.0
21 hard palate cancer 10.0
22 hemifacial spasm 10.0
23 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 10.0
24 epicanthus 9.9
25 trichorhinophalangeal syndrome, type ii 9.9
26 glaucoma 3, primary congenital, a 9.9
27 hallermann-streiff syndrome 9.9
28 astigmatism 9.9
29 blepharospasm, benign essential 9.9
30 scheie syndrome 9.9
31 muscle hypertrophy 9.9
32 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.9
33 mucopolysaccharidosis-plus syndrome 9.9
34 hematopoietic stem cell transplantation 9.9
35 erythema multiforme 9.9
36 sensorineural hearing loss 9.9
37 corneal disease 9.9
38 monocular esotropia 9.9
39 microphthalmia 9.9
40 enophthalmos 9.9
41 allergic conjunctivitis 9.9
42 lagophthalmos 9.9
43 primary angle-closure glaucoma 9.9
44 blepharoconjunctivitis 9.9
45 dermatitis 9.9
46 dystonia 9.9
47 conjunctivitis 9.9
48 eyelid carcinoma 9.9
49 fundus dystrophy 9.9
50 dermatophytosis 9.9

Comorbidity relations with Entropion via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Entropion:



Diseases related to Entropion

Symptoms & Phenotypes for Entropion

UMLS symptoms related to Entropion:


erythema of the eyelids

Drugs & Therapeutics for Entropion

Drugs for Entropion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Not Applicable 6740-88-1 3821
2
Desflurane Approved Not Applicable 57041-67-5 42113
3
Sevoflurane Approved, Vet_approved Not Applicable 28523-86-6 5206
4
Fluorometholone Approved, Investigational Not Applicable 426-13-1 9878
5 Pharmaceutical Solutions Not Applicable
6 Anesthetics Not Applicable
7 Excitatory Amino Acid Antagonists Not Applicable
8 Analgesics Not Applicable
9 Central Nervous System Depressants Not Applicable
10 Neurotransmitter Agents Not Applicable
11 Anesthetics, Dissociative Not Applicable
12 Anesthetics, Intravenous Not Applicable
13 Excitatory Amino Acids Not Applicable
14 Peripheral Nervous System Agents Not Applicable
15 Platelet Aggregation Inhibitors Not Applicable
16 Anesthetics, General Not Applicable
17 Anesthetics, Inhalation Not Applicable
18 Lubricant Eye Drops Not Applicable
19 Hormone Antagonists Not Applicable
20 Ophthalmic Solutions Not Applicable
21 Anti-Inflammatory Agents Not Applicable
22 Anti-Allergic Agents Not Applicable
23 glucocorticoids Not Applicable
24 Hormones Not Applicable
25 Hormones, Hormone Substitutes, and Hormone Antagonists Not Applicable
26 Antibiotics, Antitubercular Not Applicable
27 Anti-Bacterial Agents Not Applicable

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 A Trial of Non-absorbable Versus Absorbable Sutures for Trichiasis Surgery Completed NCT00522860 Phase 4
2 PMCF-study Using Novosyn® Quick Suture Material in Ophthalmic Surgery Withdrawn NCT02761083 Phase 4
3 Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface Surgeries Unknown status NCT02638610 Not Applicable
4 Hyper-CL™ Lens (Hyper Osmotic Contact Lens) In Subjects Suffering From Corneal Edema Unknown status NCT01890252 Not Applicable saline solution
5 Eyelash Line Resection for Entropion Associated With Down's Syndrome Completed NCT01758718 Not Applicable
6 The Effect of Preoperative Ketamine on the Emergence Characteristics in Children Undergoing Entropion Surgery Completed NCT02916407 Not Applicable Sevoflurane;Desflurane
7 A Prospective Double-blind Interventional Study of Tissue Reaction to Polyglycolic Acid Sutures in Human Skin Completed NCT01598376 Not Applicable
8 Minimally Invasive Holmium:YAG Laser Blepharoplasty Completed NCT00842764 Not Applicable
9 Fluorometholone as Ancillary Therapy for TT Surgery Completed NCT01949454 Not Applicable Fluorometholone 0.1% ophthalmic solution
10 A Trial of Epilation Verses Surgery for Minor Trichiasis Completed NCT00522912 Not Applicable
11 Study of Using the Hyper-CL™ Lens (Hyper Osmotic Contact Lens) in Subjects Suffering From Corneal Edema Completed NCT02660151 Not Applicable Salt solution
12 Lacrimal Drainage Resistance Study Completed NCT01766232
13 Validating the Diagnostic Accuracy of Mediview 2.0 Software as an Image Analysis Tool of Meibomian Glands Completed NCT01991132 Not Applicable
14 Comparison Between iLux™ and LipiFlow® in the Treatment of Meibomian Gland Dysfunction Completed NCT03055832 Not Applicable
15 IRIS Registry: Intelligent Research in Sight Registry Recruiting NCT02485847

Search NIH Clinical Center for Entropion

Cochrane evidence based reviews: entropion

Genetic Tests for Entropion

Anatomical Context for Entropion

MalaCards organs/tissues related to Entropion:

42
Skin, Eye, Testes

Publications for Entropion

Articles related to Entropion:

(show top 50) (show all 534)
# Title Authors Year
1
A conjunctival-sparing surgical technique for lower eyelid cicatricial entropion repair in ocular cicatricial pemphigoid. ( 30732510 )
2019
2
Correction of Recalcitrant Cicatricial Lower Lid Retraction and Entropion With Transverse Tarsotomy and Tarsoconjunctival Flap. ( 30365475 )
2019
3
Exposure, entropion, and bilateral corneal ulceration in a newborn as a manifestation of chromosome 22 q11.2 duplication syndrome. ( 30505980 )
2019
4
A comparison of the lateral tarsal strip with everting sutures and the Quickert procedure for involutional entropion. ( 30916886 )
2019
5
Comparison of four Combined Procedures for Correction of Involutional Lower Eyelid Entropion. ( 30882581 )
2019
6
Wedge resection of the tarsal plate combined with the modified Hotz procedure for correction of involutional lower eyelid entropion. ( 30851760 )
2019
7
The use of hyaluronic acid subdermal filler for entropion in canines and felines: 40 cases. ( 29520917 )
2019
8
Involutional entropion repair combining the modified Bick quick strip procedure with Quickert rotational sutures. ( 30024812 )
2019
9
Vector analysis of changes in corneal astigmatism following lateral tarsal strip procedure in patients with involutional ectropion or entropion. ( 30054850 )
2018
10
Management of Severe Cicatricial Entropion With Labial Mucous Membrane Graft in Cicatricial Ocular Surface Disorders. ( 29762330 )
2018
11
Comment on "Anterior lamellar recession for management of upper eyelid cicatricial entropion and associated eyelid abnormalities". ( 29977827 )
2018
12
"The influence of orbital vector on involutional entropion and ectropion". ( 28853964 )
2018
13
Entropion and ectropion repair: a snapshot of surgical practice in the United Kingdom. ( 29053043 )
2018
14
The Prevalence of Lower Eyelid Fornix Fat Prolapse: A Diagnostic Measure of Involutional Entropion. ( 30479717 )
2018
15
Synchronous Surgical Treatment of Lower Eyelid Involutional Entropion and Ptosis. ( 30534454 )
2018
16
Combined pentagonal resection and inferior retractor plication in involutional entropion. ( 30567578 )
2018
17
Lower eyelid entropion repair with retractor mobilization and insertion onto the anterior surface of the tarsal plate. ( 29040033 )
2018
18
Association of Involutional Lower Eyelid Entropion with Reduced Upper Eyelid Position Relative to the Corneal Light Reflex: Quantification of Facial Asymmetry. ( 29342029 )
2018
19
Correction of upper eyelid entropion: Modified techniques are most welcome. ( 29380775 )
2018
20
Surgical correction of involutional lower lid entropion with lateral canthal eyelid block excision and imbrication of the capsulopalpebral ligament using non-buried non-resorbable imbricating sutures versus buried resorbable imbricating sutures. ( 29498554 )
2018
21
Anterior tarsal flap rotation combined with anterior lamellar reposition in the repair of cicatricial upper eyelid entropion. ( 29538594 )
2018
22
Involutional lower eyelid entropion: causative factors and therapeutic management. ( 30315389 )
2018
23
Diagnosis, Treatment, and Surgical Repair in a Case of Isolated Conjunctival Lichen Planus Causing Cicatricial Entropion. ( 28538610 )
2017
24
Anterior lamellar recession for management of upper eyelid cicatricial entropion and associated eyelid abnormalities. ( 29259900 )
2017
25
Modified lateral tarsal strip for involutional entropion and ectropion surgery. ( 27817116 )
2017
26
A Case of a Bilateral Cicatricial Upper Eyelid Entropion After Hematopoietic Stem Cell Transplantation in Mucopolysaccharidosis Type I. ( 26588207 )
2017
27
Long-Term Results for Entropion Repair by Tarsal Margin Rotation With Posterior Lamella Superadvancement. ( 27861402 )
2017
28
Success rate of nurse-led everting sutures for involutional lower lid entropion. ( 28085138 )
2017
29
Congenital entropion and hypotropia secondary to duplication of the inferior rectus muscle. ( 28089746 )
2017
30
Orbicularis oculi muscle tightening for involutional entropion. ( 28268157 )
2017
31
Lateral tarsal strip plus skin-muscle flap excision in the treatment of lower eyelid involutional entropion. ( 28837414 )
2017
32
Lateral tarsoligamentous sling: A successful treatment for involutional entropion in Asians as a modified lateral tarsal strip. ( 28847622 )
2017
33
Shared buccal mucosal graft for simultaneous repair of severe upper and lower eyelid cicatricial entropion. ( 26710260 )
2016
34
Modified tarsotomy for the treatment of severe cicatricial entropion. ( 27101749 )
2016
35
The prevalence of glaucoma in patients undergoing surgery for eyelid entropion or ectropion. ( 27785003 )
2016
36
Comparison of Surgical Outcome Between Quickert Suture and Quickert Suture With Modified Lateral Tarsal Strip in Involutional Lower Eyelid Entropion. ( 26703055 )
2016
37
Senile lower lid entropion successfully treated with botulinum toxin A. ( 26777720 )
2016
38
Anterior lamellar recession, blepharoplasty, and supratarsal fixation for cicatricial upper eyelid entropion without lagophthalmos. ( 26869158 )
2016
39
Manual Provocation Test for Intermittent Involutional Entropion. ( 26890660 )
2016
40
Involvement of inward upper eyelid push on the lower eyelid during eyelid closure in development of involutional lower eyelid entropion. ( 27013384 )
2016
41
Correction of involutional entropion with retractor redirection. ( 27322152 )
2016
42
Posterior layer advancement of lower eyelid retractors with transcanthal canthopexy for involutional lower eyelid entropion. ( 27419836 )
2016
43
Histopathological changes in involutional lower eyelid entropion: the tarsus is thickened! ( 27938962 )
2016
44
Bedside repair of congenital upper eyelid entropion: A variation of the Quickert suture technique. ( 29503927 )
2016
45
A hammock flap: A modified backflip flap for the surgical correction of cicatricial entropion. ( 25694396 )
2015
46
Upper lid crease approach for margin rotation in trachomatous cicatricial entropion without external sutures. ( 26677040 )
2015
47
Management of patients with confirmed and presumed mucous membrane pemphigoid undergoing entropion repair. ( 25644537 )
2015
48
Genome-Wide Association Identifies SLC2A9 and NLN Gene Regions as Associated with Entropion in Domestic Sheep. ( 26098909 )
2015
49
Involutional entropion: risk factors and surgical remedies. ( 26154839 )
2015
50
Are You Missing an Entropion? The Test of Induced Entropion 2. ( 26425881 )
2015

Variations for Entropion

ClinVar genetic disease variations for Entropion:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 46;XY;inv(6)(p22q13)dn inversion Pathogenic

Expression for Entropion

Search GEO for disease gene expression data for Entropion.

Pathways for Entropion

GO Terms for Entropion

Sources for Entropion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....