MCID: ESN022
MIFTS: 24

Eosinophilic Colitis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Eosinophilic Colitis

MalaCards integrated aliases for Eosinophilic Colitis:

Name: Eosinophilic Colitis 58 70

Characteristics:

Orphanet epidemiological data:

58
eosinophilic colitis
Prevalence: <1/1000000 (Worldwide); Age of onset: Adult,Infancy;

Classifications:

Orphanet: 58  
Rare gastroenterological diseases


External Ids:

ICD10 via Orphanet 33 K52.8
UMLS via Orphanet 71 C0267448
Orphanet 58 ORPHA402035
UMLS 70 C0267448

Summaries for Eosinophilic Colitis

MalaCards based summary : Eosinophilic Colitis is related to hypereosinophilic syndrome and eosinophilic gastroenteritis. An important gene associated with Eosinophilic Colitis is PRG2 (Proteoglycan 2, Pro Eosinophil Major Basic Protein), and among its related pathways/superpathways is Allograft rejection. Affiliated tissues include colon, bone and myeloid.

Related Diseases for Eosinophilic Colitis

Diseases related to Eosinophilic Colitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)
# Related Disease Score Top Affiliating Genes
1 hypereosinophilic syndrome 30.5 RNASE3 PRG2
2 eosinophilic gastroenteritis 30.2 RNASE3 PRG2
3 gastroenteritis 30.2 RNASE3 PRG2
4 esophagitis 29.7 RNASE3 PRG2
5 allergic disease 29.4 RNASE3 PRG2
6 rhinitis 29.4 RNASE3 PRG2
7 colitis 10.8
8 diarrhea 10.5
9 food allergy 10.2
10 esophagitis, eosinophilic, 1 10.1
11 gastrointestinal system disease 10.1
12 primary eosinophilic gastrointestinal disease 10.1
13 celiac disease 1 10.1
14 ige responsiveness, atopic 10.0
15 acute diarrhea 10.0
16 inflammatory bowel disease 10.0
17 collagenous colitis 10.0
18 constipation 10.0
19 peritonitis 10.0
20 intestinal obstruction 10.0
21 ulcerative colitis 10.0
22 crohn's disease 10.0
23 cholangitis 10.0
24 irritable bowel syndrome 10.0
25 intussusception 9.8
26 osteoporosis 9.8
27 volvulus of midgut 9.8
28 autism 9.8
29 enterocolitis 9.8
30 eosinophilic fasciitis 9.8
31 leprosy 3 9.8
32 leukemia, acute myeloid 9.8
33 allergic rhinitis 9.8
34 hypereosinophilic syndrome, idiopathic 9.8
35 bone mineral density quantitative trait locus 8 9.8
36 bone mineral density quantitative trait locus 15 9.8
37 cholangitis, primary sclerosing 9.8
38 aspergillosis 9.8
39 graft-versus-host disease 9.8
40 gastrointestinal ulceration, recurrent, with dysfunctional platelets 9.8
41 exanthem 9.8
42 lymphoplasmacytic lymphoma 9.8
43 microscopic colitis 9.8
44 lymphocytic colitis 9.8
45 crohn's colitis 9.8
46 waldenstroem's macroglobulinemia 9.8
47 lepromatous leprosy 9.8
48 primary biliary cholangitis 9.8
49 pancytopenia 9.8
50 trichuriasis 9.8

Graphical network of the top 20 diseases related to Eosinophilic Colitis:



Diseases related to Eosinophilic Colitis

Symptoms & Phenotypes for Eosinophilic Colitis

Drugs & Therapeutics for Eosinophilic Colitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical and Immunological Evaluation of Eosinophil Associated Gastrointestinal Disorders (EGID) Completed NCT00267475
2 Eosinophilic Gastrointestinal Disorders Patient Registry Withdrawn NCT01779154

Search NIH Clinical Center for Eosinophilic Colitis

Genetic Tests for Eosinophilic Colitis

Anatomical Context for Eosinophilic Colitis

MalaCards organs/tissues related to Eosinophilic Colitis:

40
Colon, Bone, Myeloid, Bone Marrow, Appendix

Publications for Eosinophilic Colitis

Articles related to Eosinophilic Colitis:

(show top 50) (show all 224)
# Title Authors PMID Year
1
Eosinophilic colitis in children: a new and elusive enemy? 61
33409540 2021
2
Histopathology of non-IBD colitis practical recommendations from pathologists of IG-IBD Group. 61
33712395 2021
3
Histopathology of Non-IBD Colitis. A practical approach from the Italian Group for the study of the gastrointestinal tract (GIPAD). 61
33686310 2021
4
Primary Eosinophilic Gastrointestinal Diseases Beyond Eosinophilic Esophagitis in Children. 61
32868666 2021
5
Prevalence of primary eosinophilic colitis in patients with chronic diarrhea and diarrhea-predominant irritable bowel syndrome. 61
33602545 2021
6
Helminth-induced regulation of T-cell transfer colitis requires intact and regulated T cell Stat6 signaling in mice. 61
33067820 2021
7
Experimental Modeling of Eosinophil-Associated Diseases. 61
33486743 2021
8
Non-IgE- or Mixed IgE/Non-IgE-Mediated Gastrointestinal Food Allergies in the First Years of Life: Old and New Tools for Diagnosis. 61
33466746 2021
9
Eosinophilic Fasciitis - Clinical Features and Therapeutic Management. 61
33422175 2020
10
Endoscopic findings of gastric lesions in patients with eosinophilic gastrointestinal disorders. 61
33269315 2020
11
Eosinophilic colitis in adults. 61
32249151 2020
12
Low prevalence of colorectal neoplasia in microscopic colitis: A large prospective multi-center study. 61
33129712 2020
13
Eosinophilic colitis: an infrequent disease with difficult diagnose. 61
32958551 2020
14
Conversion from tacrolimus to sirolimus as a treatment modality in de novo allergies and immune-mediated disorders in pediatric liver transplant recipients. 61
32428390 2020
15
Targeted Therapies for Eosinophilic Gastrointestinal Disorders. 61
32472465 2020
16
Association Between Endoscopic and Histologic Findings in a Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders. 61
31773359 2020
17
Herpes simplex virus type 2 meningitis as a manifestation of Good's syndrome. 61
31858482 2020
18
Eosinophilic colitis: clinical review and 2020 update. 61
31994372 2020
19
Clozapine-Related Diarrhea and Colitis: Report of 4 Cases. 61
32332465 2020
20
Eosinophilic colitis in a boy with a novel XIAP mutation: a case report. 61
32305064 2020
21
Lamotrigine-induced DRESS Syndrome Manifesting as 'Eosinophilic Colitis': An Uncommon Presentation of a Very Uncommon Condition. 61
32391219 2020
22
Eosinophilic Colitis and Clostridioides difficile Sepsis With Rapid Remission After Antimicrobial Treatment; A Rare Coincidence and Its Pathogenic Implications. 61
32903297 2020
23
A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon. 61
32292621 2020
24
Eosinophilic Gastrointestinal Diseases in Children: A Practical Review. 61
31642786 2020
25
Eosinophil counts in colonic tissue eosinophilia: Investigating specificity and sensitivity of cutoff points and comparing two counting methods. 61
31997777 2020
26
Eosinophilic Gastrointestinal Disorders. 61
30903439 2019
27
Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. 61
30922989 2019
28
Eosinophilic colitis: A clinical review. 61
31122823 2019
29
Severe anaemia after gastric biopsy in an infant with eosinophilic gastritis. 61
31171002 2019
30
Eosinophilic colitis as a cause of intestinal obstruction: A case study. 61
30337117 2019
31
Eosinophilic Colitis Showing Multiple Submucosal Tumor-Like Protrusions. 61
30676368 2019
32
Prevalence of eosinophilic colitis and the diagnoses associated with colonic eosinophilia. 61
30654053 2019
33
Eosinophilic colitis and colonic eosinophilia. 61
30480590 2019
34
Anti-Epileptic Medication-Induced Asymptomatic Eosinophilic Colitis. 61
30627270 2018
35
Neonatal transient eosinophilic colitis with single bubble sign. 61
30585403 2018
36
Eosinophilic Colitis Associated with Emtricitabine/Tenofovir. 61
30648039 2018
37
Eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis. 61
29940308 2018
38
[Primary eosinophilic colitis in a celiac patient]. 61
29943760 2018
39
Severe eosinophilic colitis caused by neuropathic agents in a patient with chronic fatigue syndrome and functional abdominal pain: case report and review of the literature. 61
29890559 2018
40
Clinical Implications of Pediatric Colonic Eosinophilia. 61
29095349 2018
41
Eosinophilic gastroenteritis and other eosinophilic gut diseases distal to the oesophagus. 61
29533199 2018
42
Fecal calprotectin: beyond intestinal organic diseases. 61
29370679 2018
43
Eosinophilic colitis: Case series and literature review. 61
29103770 2018
44
Eosinophilic Gastrointestinal Diseases in Childhood. 61
30783041 2018
45
Classification of eosinophilic disorders of the small and large intestine. 61
29127496 2018
46
Prevalence of Eosinophilic Gastroenteritis and Colitis in a Population-Based Study, From 2012 to 2017. 61
28603057 2017
47
Eosinophilic Colitis Masquerading as Malignancy of Colon. 61
29118877 2017
48
[Concurrent lymphocytic colitis and microscopic enteritis in patients with chronic diarrhea]. 61
29459804 2017
49
Eosinophilic Colitis-"Not as rare". 61
28546064 2017
50
Hematochezia caused by eosinophilic proctocolitis in a newborn before oral feeding: a case report. 61
28619048 2017

Variations for Eosinophilic Colitis

Expression for Eosinophilic Colitis

Search GEO for disease gene expression data for Eosinophilic Colitis.

Pathways for Eosinophilic Colitis

Pathways related to Eosinophilic Colitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.37 RNASE3 PRG2

GO Terms for Eosinophilic Colitis

Biological processes related to Eosinophilic Colitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 8.96 RNASE3 PRG2
2 defense response to bacterium GO:0042742 8.62 RNASE3 PRG2

Sources for Eosinophilic Colitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....