MCID: ESN008
MIFTS: 54

Eosinophilic Pneumonia

Categories: Rare diseases, Respiratory diseases, Immune diseases

Aliases & Classifications for Eosinophilic Pneumonia

MalaCards integrated aliases for Eosinophilic Pneumonia:

Name: Eosinophilic Pneumonia 12 15 73
Pneumonia, Eosinophilic 12 76 53
Pulmonary Eosinophilia 44 73
Pulmonary Infiltrates with Eosinophilia 53
Asthmatic Pulmonary Eosinophilia 73
Simple Pulmonary Eosinophilia 73
Pneumonia Eosinophilic 55
Loeffler Syndrome 53

Classifications:



External Ids:

Disease Ontology 12 DOID:5870
ICD10 33 J82
MeSH 44 D011657
NCIt 50 C35150

Summaries for Eosinophilic Pneumonia

Disease Ontology : 12 A pneumonia in which certain type of white blood cell called an eosinophil accumulates in the lung. These cells cause disruption of the normal air spaces (alveoli) where oxygen is extracted from the atmosphere. It is caused by certain medications or environmental triggers, parasitic infections, and cancer. The most common symptoms include cough, fever, difficulty breathing, and sweating at night.

MalaCards based summary : Eosinophilic Pneumonia, also known as pneumonia, eosinophilic, is related to chronic eosinophilic pneumonia and pulmonary eosinophilia, and has symptoms including hemoptysis and coughing. An important gene associated with Eosinophilic Pneumonia is IL5 (Interleukin 5), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Nitric Oxide and Omalizumab have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and bone, and related phenotypes are hematopoietic system and immune system

Wikipedia : 76 Eosinophilic pneumonia (EP) is a disease in which an eosinophil, a type of white blood cell, accumulates... more...

Related Diseases for Eosinophilic Pneumonia

Diseases in the Eosinophilic Pneumonia family:

Chronic Eosinophilic Pneumonia

Diseases related to Eosinophilic Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)
# Related Disease Score Top Affiliating Genes
1 chronic eosinophilic pneumonia 33.4 CCL11 CCL5 IL5 RNASE3
2 pulmonary eosinophilia 30.5 CCL11 CCL17 CCL5 IL13 IL5 RNASE3
3 churg-strauss syndrome 30.2 CCL17 IL5 RNASE3
4 aspergillosis 30.1 CCL17 IL5 SFTPD
5 interstitial lung disease 29.8 CCL17 CCL5 SFTPD
6 allergic bronchopulmonary aspergillosis 29.8 CCL17 IL5 SFTPD
7 pneumonia 29.7 CCL11 CCL5 IL13 IL5 SFTPD
8 gastroenteritis 29.5 CCL11 IL5 RNASE3
9 bronchitis 29.5 CCL11 IL5 RNASE3
10 bullous pemphigoid 29.0 CCL11 CCL17 IL5 RNASE3
11 schistosomiasis 28.6 IL13 IL5 RNASE3
12 bronchiolitis 28.0 CCL11 CCL5 IL13 IL5 RNASE3
13 psoriasis 28.0 CCL17 CCL22 CCL5 IL13
14 eosinophilic gastroenteritis 27.6 CCL11 CSF2 IL3 IL5 RNASE3
15 lung disease 27.6 CCL5 CSF2 IL13 IL5 SFTPD
16 pulmonary disease, chronic obstructive 27.3 CCL11 CCL5 IL13 RNASE3 SFTPD
17 hypereosinophilic syndrome 25.6 CCL11 CCL17 CSF2 IL13 IL3 IL5
18 asthma 24.8 CCL11 CCL17 CCL22 CCL5 CSF2 IL13
19 idiopathic acute eosinophilic pneumonia 12.5
20 loeffler syndrome 11.0
21 pemphigoid gestationis 10.7 CCL11 IL5
22 chronic meningitis 10.6 CCL11 IL5
23 vulvovaginitis 10.5 CCL11 CCL5
24 loeffler endocarditis 10.5 IL5 RNASE3
25 radiculopathy 10.5 CCL5 IL5
26 cough variant asthma 10.4 IL5 RNASE3
27 cow milk allergy 10.4 IL5 RNASE3
28 blepharoconjunctivitis 10.4 CCL11 RNASE3
29 giant papillary conjunctivitis 10.3 CCL11 RNASE3
30 maxillary sinusitis 10.3 CCL5 RNASE3
31 cellulitis 10.3 IL5 RNASE3
32 yellow fever 10.3 CCL5 IL5
33 acute cervicitis 10.3 CCL5 CSF2
34 sinusitis 10.3 IL5 RNASE3
35 folliculitis 10.3 CCL11 CCL5 IL5
36 hypereosinophilic syndrome, idiopathic 10.3 IL3 IL5
37 necatoriasis 10.2 CCL17 CCL22 IL5
38 milk allergy 10.2 IL5 RNASE3
39 echinococcosis 10.2 CCL17 IL5
40 contact dermatitis 10.2 CCL17 CCL22 IL5
41 respiratory failure 10.2
42 wells syndrome 10.2 IL5 RNASE3
43 mycosis fungoides 10.2 CCL17 CCL22 IL5
44 stachybotrys chartarum 10.1 CCL5 IL3
45 cytokine deficiency 10.1 IL13 IL5
46 angioimmunoblastic lymphadenopathy with dysproteinemia 10.1 IL13 IL5
47 status asthmaticus 10.1 CCL5 IL5 RNASE3
48 arthritis 10.1
49 rheumatoid arthritis 10.0
50 felty syndrome 10.0 CSF2 IL3

Graphical network of the top 20 diseases related to Eosinophilic Pneumonia:



Diseases related to Eosinophilic Pneumonia

Symptoms & Phenotypes for Eosinophilic Pneumonia

UMLS symptoms related to Eosinophilic Pneumonia:


hemoptysis, coughing

MGI Mouse Phenotypes related to Eosinophilic Pneumonia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.7 CCL5 CSF2 IL13 IL5 SFTPD CCL11
2 immune system MP:0005387 9.56 CCL22 CCL5 CSF2 IL13 IL5 SFTPD
3 respiratory system MP:0005388 9.02 CSF2 IL13 IL5 SFTPD CCL11

Drugs & Therapeutics for Eosinophilic Pneumonia

Drugs for Eosinophilic Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 52)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nitric Oxide Approved Phase 4 10102-43-9 145068 160954
2
Omalizumab Approved, Investigational Phase 4 242138-07-4
3
Ciclesonide Approved, Investigational Phase 4 126544-47-6, 141845-82-1 444033
4
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
5
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
6
Budesonide Approved Phase 4 51333-22-3 63006 5281004
7 Prednisolone acetate Phase 4,Phase 3
8 glucocorticoids Phase 4,Phase 2,Phase 3
9 Respiratory System Agents Phase 4,Phase 3,Phase 2
10 Methylprednisolone acetate Phase 4,Phase 3
11 Methylprednisolone Hemisuccinate Phase 4,Phase 3
12 Adrenergic Agents Phase 4,Phase 2
13 Adrenergic Agonists Phase 4,Phase 2
14 Adrenergic beta-2 Receptor Agonists Phase 4,Phase 2
15 Adrenergic beta-Agonists Phase 4,Phase 2
16 Albuterol Phase 4,Phase 2
17 Gastrointestinal Agents Phase 4
18 Neuroprotective Agents Phase 4
19 Neurotransmitter Agents Phase 4,Phase 2
20 Tocolytic Agents Phase 4,Phase 2
21 Hormone Antagonists Phase 4,Phase 2,Phase 3
22 Hormones Phase 4,Phase 2,Phase 3
23 Anti-Allergic Agents Phase 4,Phase 2
24 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3
25 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
26 Peripheral Nervous System Agents Phase 4,Phase 2
27 Antibodies Phase 4,Phase 3,Phase 2
28 Immunoglobulins Phase 4,Phase 3,Phase 2
29 Antibodies, Monoclonal Phase 4,Phase 3,Phase 2
30 Prednisolone hemisuccinate Phase 4,Phase 3
31 Prednisolone phosphate Phase 4,Phase 3
32 Antiemetics Phase 4
33 Protective Agents Phase 4
34 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3
35 Autonomic Agents Phase 4,Phase 2
36 Bronchodilator Agents Phase 4,Phase 2
37 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3
38 Fluorodeoxyglucose F18 Phase 4
39 Radiopharmaceuticals Phase 4
40
Prednisone Approved, Vet_approved Phase 2, Phase 3,Phase 3 53-03-2 5865
41
Citric Acid Approved, Nutraceutical, Vet_approved Phase 3 77-92-9 311
42 Pharmaceutical Solutions Phase 3,Phase 2
43 Immunoglobulin G Phase 3
44 Citrate Nutraceutical Phase 3
45
Fluticasone Approved, Experimental, Investigational Phase 2 90566-53-3 62924
46
Salmeterol xinafoate Phase 2 94749-08-3 56801
47 Fluticasone Propionate, Salmeterol Xinafoate Drug Combination Phase 2
48 Dermatologic Agents Phase 2
49 Indoleacetic Acids Phase 2
50
Daptomycin Approved, Investigational 103060-53-3 16129629

Interventional clinical trials:

(show all 35)
# Name Status NCT ID Phase Drugs
1 The Efficacy of Three Months-prednisolone Therapy for Chronic Eosinophilic Pneumonia Completed NCT00632554 Phase 4 prednisolone 0.5 mg/kg/day for three months;prednisolone 0.5 mg/kg/day for six months
2 Omalizumab to Mepolizumab Switch Study in Severe Eosinophilic Asthma Patients Completed NCT02654145 Phase 4 Mepolizumab 100mg SC;Albuterol/salbutamol MDIs;Omalizumab
3 Small Particle Steroids in Refractory Asthma Completed NCT01171365 Phase 4 Ciclesonide;Placebo
4 An Imaging Study Using PET/CT to Characterize the Effect of Intravenous Reslizumab on Airway Inflammation Recruiting NCT02937168 Phase 4 Reslizumab;Fludeoxyglucose F 18 (FDG);Placebo
5 The RECONSTRUCT Study - Reconstructing Disease Mechanisms in Asthma Recruiting NCT03034005 Phase 4 Budesonide
6 A Study to Evaluate the Efficacy and Safety of Reslizumab in Patients With Eosinophilic Asthma Completed NCT01285323 Phase 3 Reslizumab;Placebo
7 A Study to Evaluate the Efficacy and Safety of Reslizumab (3.0 mg/kg) in the Reduction of Clinical Asthma Exacerbations in Patients (12-75 Years of Age) With Eosinophilic Asthma Completed NCT01287039 Phase 3 Reslizumab;Placebo
8 A Study to Evaluate the Efficacy and Safety of Reslizumab (0.3 or 3.0 mg/kg) as Treatment for Patients (12-75 Years of Age) With Eosinophilic Asthma Completed NCT01270464 Phase 3 Reslizumab;Placebo
9 Efficacy and Safety Study of Mepolizumab Adjunctive Therapy in Participants With Severe Eosinophilic Asthma on Markers of Asthma Control Completed NCT02281318 Phase 3 Placebo;SOC
10 Anti-Interleukin-5 (IL5) Monoclonal Antibody (MAb) in Prednisone-dependent Eosinophilic Asthma Completed NCT02559791 Phase 2, Phase 3 Placebo
11 Study of Mepolizumab Autoinjector in Asthmatics Completed NCT03099096 Phase 3 Mepolizumab
12 Study of Mepolizumab Safety Syringe in Asthmatics Completed NCT03021304 Phase 3 Mepolizumab
13 Study to Evaluate the Efficacy and Safety of Reslizumab Treatment in Patients With Moderate to Severe Asthma Completed NCT01508936 Phase 3 Reslizumab;Placebo
14 A Phase 3a, Repeat Dose, Open-label, Long-term Safety Study of Mepolizumab in Asthmatic Subjects Completed NCT02135692 Phase 3 SOC
15 Cessation Versus Continuation of Long-term Mepolizumab in Severe Eosinophilic Asthma Patients Recruiting NCT02555371 Phase 3 Placebo
16 Efficacy and Safety Study of Mepolizumab in Subjects With Severe Hypereosinophilic Syndrome (HES) Recruiting NCT02836496 Phase 3 Mepolizumab 300 mg;Placebo matching mepolizumab;Active OCS capsules (5 mg prednisolone or prednisone);Placebo matching OCS capsules
17 Benralizumab in Patients With Inadequate Response to Anti-IL5 Monoclonal Antibody Therapies Not yet recruiting NCT03470311 Phase 3
18 Study to Evaluate Efficacy and Safety of Benralizumab in Reducing Oral Corticosteroid Use in Adult Patients With Severe Asthma Not yet recruiting NCT03557307 Phase 3
19 Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Reslizumab (3.0 mg/kg) as Treatment for Patients (12 Through 75 Years of Age) With Eosinophilic Asthma Terminated NCT01290887 Phase 3 Reslizumab
20 Effects of Mepolizumab Compared to Placebo on Airway Physiology in Patients With Eosinophilic Asthma: MEMORY Study Terminated NCT02594332 Phase 3 Mepolizumab;Placebo
21 A Study of Reslizumab in Patients 12 Years of Age and Older With Severe Eosinophilic Asthma Terminated NCT03052725 Phase 3 reslizumab
22 A Phase IIa Study of KHK4563 Completed NCT01412736 Phase 2 KHK4563;KHK4563;KHK4563;Placebo
23 Efficacy, Safety, and Tolerability of Dupilumab in Patients With Persistent Moderate to Severe Eosinophilic Asthma Completed NCT01312961 Phase 2 Dupilumab;Placebo (for Dupilumab);Fluticasone/Salmeterol combination therapy;Fluticasone monotherapy;Albuterol;Levalbuterol
24 Pharmacokinetics and Pharmacodynamics of Mepolizumab Administered Subcutaneously in Children Completed NCT02377427 Phase 2 Mepolizumab
25 Proof of Concept Study to Investigate ANB020 Activity in Adult Patients With Severe Eosinophilic Asthma Recruiting NCT03469934 Phase 2 ANB020;Placebo
26 Effect of OC000459 on Eosinophilic Airway Inflammation in Severe Asthma Recruiting NCT02560610 Phase 2 OC000459;Placebo
27 Effect of Benralizumab in Atopic Dermatitis Not yet recruiting NCT03563066 Phase 2 Benralizumab;Placebo Control
28 Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Bacterial Pneumonia Unknown status NCT01152424
29 Effect of Mepolizumab on Decrease of Systemic Corticosteroids in Patients With Severe Eosinophilic Asthma Completed NCT03453021 Mepolizumab
30 Daptomycin > 6 mg/kg/Day as Salvage Therapy in Patients With Complex Bone and Joint Infection: Cohort Study in a Regionalreference Center Completed NCT03209934
31 Exploring Asthma Exacerbations in Mepolizumab Treated Patients Recruiting NCT03324230
32 Identifying Serum Cytokine Profiles of Distinct Inflammatory Phenotypes in Severe Asthma Recruiting NCT03563521
33 Study of Chronic Rhinosinusitis Symptoms in Asthma Patients Undergoing Treatment With Reslizumab Recruiting NCT03369574 Reslizumab
34 European Management Platform for Childhood Interstitial Lung Diseases - chILD-EU Register and Biobank Recruiting NCT02852928
35 Observational Study of Characteristics, Treatment and Outcomes With Severe Asthma in the United States (CHRONICLE) Recruiting NCT03373045

Search NIH Clinical Center for Eosinophilic Pneumonia

Cochrane evidence based reviews: pulmonary eosinophilia

Genetic Tests for Eosinophilic Pneumonia

Anatomical Context for Eosinophilic Pneumonia

MalaCards organs/tissues related to Eosinophilic Pneumonia:

41
Lung, Testes, Bone, T Cells, Bone Marrow, Breast, Thymus

Publications for Eosinophilic Pneumonia

Articles related to Eosinophilic Pneumonia:

(show top 50) (show all 524)
# Title Authors Year
1
Acute eosinophilic pneumonia in the deployed military setting. ( 29605194 )
2018
2
A case of cocaine-induced eosinophilic pneumonia: Case report and review of the literature. ( 29487790 )
2018
3
A recurrent case of eosinophilic pneumonia with high IL-25 levels. ( 29779833 )
2018
4
Acute eosinophilic pneumonia associated with smoking: a case report. ( 29915648 )
2018
5
Daptomycin eosinophilic pneumonia: an adverse effect to be aware of. ( 29791122 )
2018
6
Eosinophilic pneumonia induced by non-steroidal anti-inflammatory drugs: An underestimated risk. ( 29789133 )
2018
7
Risperidone-Associated Acute Eosinophilic Pneumonia. ( 29889675 )
2018
8
Daptomycin-induced Eosinophilic Pneumonia and a Review of the Published Literature. ( 29093391 )
2018
9
Long-term management and persistent impairment of pulmonary function in chronic eosinophilic pneumonia: A review of the previous literature. ( 29395966 )
2018
10
The Onset of Eosinophilic Pneumonia Preceding Anti-synthetase Syndrome. ( 29093389 )
2018
11
Sertraline-Induced Acute Eosinophilic Pneumonia. ( 29607784 )
2018
12
Two patients with daptomycin induced eosinophilic pneumonia with different presentations and treatment. ( 29201637 )
2018
13
Daptomycin associated eosinophilic pneumonia: case report and differential diagnoses. ( 29915657 )
2018
14
Drug-induced eosinophilic pneumonia: A review of 196 case reports. ( 29369189 )
2018
15
Pulmonary Actinomycosis in a Patient with Chronic Eosinophilic Pneumonia treated with Omalizumab. ( 28720253 )
2017
16
Levetiracetam-induced eosinophilic pneumonia. ( 28275024 )
2017
17
Response to Omalizumab in a Patient With Chronic Eosinophilic Pneumonia and Poor Response to Corticosteroids. ( 29258701 )
2017
18
Chronic eosinophilic pneumonia after radiation therapy for squamous cell lung cancer. ( 28831373 )
2017
19
Eosinophil transendothelial migration induced by the bronchoalveolar lavage fluid of acute eosinophilic pneumonia. ( 28139852 )
2017
20
Drug-induced eosinophilic pneumonia in a patient with Crohn's disease: diagnosis and treatment using fraction of exhaled nitric oxide. ( 29142522 )
2017
21
Possible Role of IL-25 in Eosinophilic Lung Inflammation in Patients with Chronic Eosinophilic Pneumonia. ( 28875265 )
2017
22
Acute Eosinophilic Pneumonia and Tracheitis Associated with Smoking. ( 28530497 )
2017
23
Lenalidomide-induced eosinophilic pneumonia. ( 28451433 )
2017
24
Acute eosinophilic pneumonia following artenimol-piperaquine exposure. ( 28499010 )
2017
25
Chronic eosinophilic pneumonia: Adjunctive therapy with inhaled steroids. ( 28626631 )
2017
26
Chronic Eosinophilic Pneumonia: A Diagnostic Challenge. ( 28694046 )
2017
27
Memory-type ST2(+)CD4(+) T cells participate in the steroid-resistant pathology of eosinophilic pneumonia. ( 28754914 )
2017
28
Mesalamine induced eosinophilic pneumonia. ( 28458997 )
2017
29
Acute eosinophilic pneumonia secondary to heroin inhalation. ( 28990896 )
2017
30
Daptomycin-Induced Acute Eosinophilic Pneumonia: Late Onset and Quick Recovery. ( 29225987 )
2017
31
Acute Eosinophilic Pneumonia: Correlation of Clinical Characteristics With Underlying Cause. ( 28286263 )
2017
32
The reversed halo sign: also think about chronic eosinophilic pneumonia. ( 29365007 )
2017
33
Progesterone as a cause of eosinophilic pneumonia after<i>in vitro</i>fertilization. ( 29296250 )
2017
34
Menthol-Flavored Cigarettes: Potentially a Strong Trigger of Acute Eosinophilic Pneumonia. ( 28117040 )
2017
35
Persistent impairment on spirometry in chronic eosinophilic pneumonia: a longitudinal observation study (Shizuoka-CEP study). ( 28942952 )
2017
36
Osimertinib-Induced Interstitial Lung Disease Presenting as Eosinophilic Pneumonia. ( 28748819 )
2017
37
Acute Eosinophilic Pneumonia: Causes, Diagnosis and Management. ( 29206477 )
2017
38
Elevated uric acid and adenosine triphosphate concentrations in bronchoalveolar lavage fluid of eosinophilic pneumonia. ( 28705588 )
2017
39
Daptomycin-associated eosinophilic pneumonia with rechallenge: a case reporta8c. ( 28406091 )
2017
40
Chronic eosinophilic pneumonia presenting with ipsilateral pleural effusion: a case report. ( 27520469 )
2016
41
Acute eosinophilic pneumonia. ( 26891699 )
2016
42
Toxocara canis-Associated Myelitis with Eosinophilic Pneumonia. ( 27358582 )
2016
43
Eosinophilic pneumonia as complication of linear IgA dermatosis treated with dapsone. ( 27886442 )
2016
44
Poster 53 Daptomycin-Induced Acute Eosinophilic Pneumonia in a Patient Receiving Rehabilitation Post Prosthetic Joint Infection: A Case Report. ( 27672819 )
2016
45
A pediatric case of Fascioliasis with eosinophilic pneumonia. ( 27922247 )
2016
46
Eosinophilic pneumonia associated with pirfenidone therapy. ( 27390279 )
2016
47
Eosinophilic pneumonia caused by daptomycin: Six cases from two institutions and a review of the literature. ( 28003110 )
2016
48
Acute Eosinophilic Pneumonia with Respiratory Failure Induced by Synthetic Cannabinoid Inhalation. ( 27994925 )
2016
49
Current Approach to Diagnosis and Management of Pulmonary Eosinophilic Syndromes: Eosinophilic Pneumonias, Eosinophilic Granulomatosis with Polyangiitis, and Hypereosinophilic Syndrome. ( 27231866 )
2016
50
Acute eosinophilic pneumonia following recent cigarette smoking. ( 27642564 )
2016

Variations for Eosinophilic Pneumonia

Expression for Eosinophilic Pneumonia

Search GEO for disease gene expression data for Eosinophilic Pneumonia.

Pathways for Eosinophilic Pneumonia

Pathways related to Eosinophilic Pneumonia according to GeneCards Suite gene sharing:

(show all 28)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.81 CCL11 CCL22 CCL5 CSF2 IL13 IL3
2
Show member pathways
13.61 CCL11 CCL17 CCL22 CCL5 CSF2 IL13
3
Show member pathways
13.44 CCL11 CCL17 CCL22 CCL5 CSF2 IL13
4
Show member pathways
13.29 CCL11 CCL17 CCL22 CCL5 IL13 IL3
5
Show member pathways
13.15 CCL11 CCL17 CCL22 CCL5 CSF2 IL13
6
Show member pathways
13.13 CCL11 CCL22 CCL5 CSF2 IL13 IL3
7
Show member pathways
12.99 CCL11 CCL17 CCL22 CCL5 CSF2 IL13
8
Show member pathways
12.7 CCL11 IL13 IL3 IL5 RNASE3
9
Show member pathways
12.69 CCL11 CCL17 CCL22 CCL5
10
Show member pathways
12.47 CSF2 IL13 IL3 IL5
11
Show member pathways
12.42 CSF2 IL13 IL3 IL5
12
Show member pathways
12.16 CCL11 CCL17 CSF2 IL13 IL5
13
Show member pathways
11.98 CSF2 IL3 IL5
14 11.85 CSF2 IL3 IL5
15 11.84 CCL11 CCL22 IL13
16
Show member pathways
11.82 CCL11 CCL17 CCL22 CCL5
17 11.76 CSF2 IL3 IL5
18 11.67 CSF2 IL13 IL5
19
Show member pathways
11.62 CSF2 IL3 IL5
20 11.52 CCL11 CCL17 IL5
21
Show member pathways
11.51 CCL11 CCL17 CCL22 CCL5 IL13 IL3
22 11.38 CSF2 IL3 IL5
23 11.36 CCL22 CCL5 CSF2 IL13
24 11.35 CCL11 CCL5 CSF2 IL13 IL5
25 11.14 IL13 IL5
26 11.04 IL13 IL5
27 11.03 CSF2 IL13 IL3 IL5
28 10.68 CCL11 CCL17 CCL22 IL13 IL5

GO Terms for Eosinophilic Pneumonia

Cellular components related to Eosinophilic Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 CCL11 CCL17 CCL22 CCL5 CSF2 IL13
2 extracellular space GO:0005615 9.32 CCL11 CCL17 CCL22 CCL5 CSF2 IL13

Biological processes related to Eosinophilic Pneumonia according to GeneCards Suite gene sharing:

(show all 26)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of GTPase activity GO:0043547 9.88 CCL11 CCL17 CCL22 CCL5
2 cell-cell signaling GO:0007267 9.87 CCL17 CCL22 CCL5 IL3
3 MAPK cascade GO:0000165 9.85 CCL5 CSF2 IL3 IL5
4 inflammatory response GO:0006954 9.85 CCL11 CCL17 CCL22 CCL5 IL13 IL5
5 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.84 CCL11 CCL17 CCL22 CCL5
6 chemotaxis GO:0006935 9.83 CCL11 CCL17 CCL22 CCL5
7 cellular response to tumor necrosis factor GO:0071356 9.81 CCL11 CCL17 CCL22 CCL5
8 cellular response to interferon-gamma GO:0071346 9.8 CCL11 CCL17 CCL22 CCL5
9 peptidyl-tyrosine phosphorylation GO:0018108 9.78 CSF2 IL3 IL5
10 cellular response to interleukin-1 GO:0071347 9.78 CCL11 CCL17 CCL22 CCL5
11 response to virus GO:0009615 9.76 CCL11 CCL22 CCL5
12 chemokine-mediated signaling pathway GO:0070098 9.76 CCL11 CCL17 CCL22 CCL5
13 neutrophil chemotaxis GO:0030593 9.73 CCL11 CCL17 CCL22 CCL5
14 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.71 CCL5 CSF2 IL13 IL3
15 cytokine-mediated signaling pathway GO:0019221 9.7 CCL11 CCL22 CCL5 CSF2 IL13 IL3
16 positive regulation of B cell proliferation GO:0030890 9.63 IL13 IL5
17 positive regulation of DNA replication GO:0045740 9.62 CSF2 IL3
18 positive regulation of JAK-STAT cascade GO:0046427 9.62 CCL5 IL5
19 monocyte chemotaxis GO:0002548 9.62 CCL11 CCL17 CCL22 CCL5
20 eosinophil chemotaxis GO:0048245 9.61 CCL11 CCL5
21 macrophage chemotaxis GO:0048246 9.6 CCL5 SFTPD
22 positive regulation of podosome assembly GO:0071803 9.59 CSF2 IL5
23 induction of bacterial agglutination GO:0043152 9.56 RNASE3 SFTPD
24 lymphocyte chemotaxis GO:0048247 9.56 CCL11 CCL17 CCL22 CCL5
25 immune response GO:0006955 9.56 CCL11 CCL17 CCL22 CCL5 CSF2 IL13
26 regulation of signaling receptor activity GO:0010469 9.23 CCL11 CCL17 CCL22 CCL5 CSF2 IL13

Molecular functions related to Eosinophilic Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 9.58 CSF2 IL3 IL5
2 growth factor activity GO:0008083 9.54 CSF2 IL3 IL5
3 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.5 CSF2 IL3 IL5
4 chemokine activity GO:0008009 9.46 CCL11 CCL17 CCL22 CCL5
5 lipopolysaccharide binding GO:0001530 9.43 RNASE3 SFTPD
6 CCR4 chemokine receptor binding GO:0031729 9.26 CCL17 CCL5
7 CCR chemokine receptor binding GO:0048020 9.26 CCL11 CCL17 CCL22 CCL5
8 cytokine activity GO:0005125 9.23 CCL11 CCL17 CCL22 CCL5 CSF2 IL13

Sources for Eosinophilic Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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