EPF
MCID: ESN016
MIFTS: 25

Eosinophilic Pustular Folliculitis (EPF)

Categories: Immune diseases, Rare diseases

Aliases & Classifications for Eosinophilic Pustular Folliculitis

MalaCards integrated aliases for Eosinophilic Pustular Folliculitis:

Name: Eosinophilic Pustular Folliculitis 20 70
Eosinophilic Folliculitis 20 70
Eosinophilic Folliculitis, Pustular 20
Ofuji's Disease 20
Ofuji Disease 20
Epf 20

Classifications:



External Ids:

UMLS 70 C0406305 C0744066

Summaries for Eosinophilic Pustular Folliculitis

GARD : 20 Eosinophilic pustular folliculitis (EPF) is a skin disorder characterized by recurring itchy, red or skin-colored bumps and pustules (bumps containing pus). The condition is named after the fact that skin biopsies of this disorder find eosinophils (a type of immune cell ) around hair follicles. The papules mostly appear on the face, scalp, neck and trunk and may persist for weeks or months. EPF affects males more than females. There are several variants of EPF including classic eosinophilic pustular folliculitis (mainly occurring in adults in Japan); HIV-associated EPF, also referred to as immunosuppression-associated EPF; and infantile EPF (with onset from birth or within the first year of life). Whether these are distinct disorders rather than variants of one disorder is controversial, partly because the underlying cause of EFP is not known. Several treatments have been described with variable results, including various oral or topical medications and phototherapy. In patients with HIV-associated disease, antiretroviral therapy tends to greatly diminish symptoms or even eliminate the condition.

MalaCards based summary : Eosinophilic Pustular Folliculitis, also known as eosinophilic folliculitis, is related to folliculitis and dermatitis, atopic. An important gene associated with Eosinophilic Pustular Folliculitis is IFNG (Interferon Gamma), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Lymphoid Cell Differentiation Pathways. Affiliated tissues include bone marrow, skin and brain.

Wikipedia : 73 Eosinophilic folliculitis is an itchy rash with an unknown cause that is most common among individuals... more...

Related Diseases for Eosinophilic Pustular Folliculitis

Diseases related to Eosinophilic Pustular Folliculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 105)
# Related Disease Score Top Affiliating Genes
1 folliculitis 31.5 PTGDR2 IFNG
2 dermatitis, atopic 29.5 PTGDR2 IFNG
3 hypereosinophilic syndrome 10.7
4 skin disease 10.5
5 acquired immunodeficiency syndrome 10.5
6 exanthem 10.4
7 dermatophytosis 10.4
8 follicular mucinosis 10.4
9 lymphoma 10.3
10 acne 10.3
11 immune deficiency disease 10.3
12 mycosis fungoides 10.2
13 mantle cell lymphoma 10.2
14 allergic disease 10.2
15 dermatomycosis 10.2
16 cellulitis 10.2
17 scabies 10.2
18 rosacea 10.2
19 wells syndrome 10.2
20 exophthalmos 10.2
21 annular erythema 10.1
22 basal cell nevus syndrome 10.1
23 dowling-degos disease 1 10.1
24 lymphoma, hodgkin, classic 10.1
25 polycythemia vera 10.1
26 cervical cancer 10.1
27 langerhans cell histiocytosis 10.1
28 lymphoma, non-hodgkin, familial 10.1
29 allergic rhinitis 10.1
30 human immunodeficiency virus type 1 10.1
31 hepatitis c virus 10.1
32 myelodysplastic syndrome 10.1
33 graft-versus-host disease 10.1
34 angiosarcoma 10.1
35 erythema multiforme 10.1
36 cutaneous t cell lymphoma 10.1
37 drug allergy 10.1
38 lymphoproliferative syndrome 10.1
39 erythema nodosum 10.1
40 gout 10.1
41 myeloproliferative neoplasm 10.1
42 basal cell carcinoma 10.1
43 acrodermatitis 10.1
44 skin atrophy 10.1
45 histiocytosis 10.1
46 hypertrichosis 10.1
47 pyoderma 10.1
48 rhinitis 10.1
49 eosinophilic pneumonia 10.1
50 polycythemia 10.1

Graphical network of the top 20 diseases related to Eosinophilic Pustular Folliculitis:



Diseases related to Eosinophilic Pustular Folliculitis

Symptoms & Phenotypes for Eosinophilic Pustular Folliculitis

Drugs & Therapeutics for Eosinophilic Pustular Folliculitis

Search Clinical Trials , NIH Clinical Center for Eosinophilic Pustular Folliculitis

Genetic Tests for Eosinophilic Pustular Folliculitis

Anatomical Context for Eosinophilic Pustular Folliculitis

MalaCards organs/tissues related to Eosinophilic Pustular Folliculitis:

40
Bone Marrow, Skin, Brain, Kidney

Publications for Eosinophilic Pustular Folliculitis

Articles related to Eosinophilic Pustular Folliculitis:

(show top 50) (show all 333)
# Title Authors PMID Year
1
A Case of Eosinophilic Pustular Folliculitis Associated With Herpes Zoster. 61
33156024 2021
2
Eosinophilic pustular folliculitis after hematopoietic stem cell transplantation: A study of 11 cases. 61
33715192 2021
3
Eosinophilic folliculitis, eosinophilic dermatosis of hematologic malignancy and acneiform follicular mucinosis: Two case reports and a review of the literature highlighting the spectrum of histopathology. 61
33617128 2021
4
Treatment of eosinophilic pustular folliculitis with benralizumab in a 13-year-old girl. 61
33594788 2021
5
A Case of Eosinophilic Pustular Folliculitis since Birth. 61
33430336 2021
6
Eosinophilic folliculitis of the scalp associated with PD-1/PDL1 inhibitors. 61
32281235 2020
7
Eosinophilic folliculitis due to wearing protective gear in citizens volunteering for sanitation services during the COVID-19 pandemic - an original epidemiological, clinical, dermoscopic, and laboratory-based study. 61
33040344 2020
8
Eosinophilic pustular folliculitis (EPF) in a patient with HIV infection. 61
33237446 2020
9
Association between eosinophilic folliculitis and follicular mucinosis. A case series. 61
32323302 2020
10
Eosinophilic pustular folliculitis with palmoplantar lesions and nail deformity. 61
32677109 2020
11
Human Polyomavirus 6 Detected in Cases of Eosinophilic Pustular Folliculitis. 61
32989462 2020
12
Eosinophilic Dermatoses: Recognition and Management. 61
32394361 2020
13
Eosinophilic pustular folliculitis on the vulva of a patient with cervical cancer. 61
32173885 2020
14
A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus. 61
32999652 2020
15
Upregulation of IL-36 cytokines in folliculitis and eosinophilic pustular folliculitis. 61
31424098 2020
16
Suspected eosinophilic pustular folliculitis presenting as rapidly evolving acneiform eruption. 61
31444983 2020
17
Malassezia (Pityrosporum) Folliculitis Incognito: Malessezia-associated Folliculitis Masked by Topical Corticosteroid Therapy. 61
32038889 2020
18
[SYSTEMIC REVIEW OF EOSINOPHILIC DERMATOSES PATIENTS TREATED WITH TNF-Α INHIBITORS AND USTEKINUMAB]. 61
31930806 2020
19
Possible roles of basophils in chronic itch. 61
29894005 2019
20
Eosinophilic dermatoses. 61
31562692 2019
21
High accuracy of recognition of common forms of folliculitis by dermoscopy: An observational study. 61
30914342 2019
22
Eosinophilic folliculitis in a patient with chronic myelomonocytic leukemia. 61
31388531 2019
23
Facial pustules due to drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms may histopathologically mimic eosinophilic pustular folliculitis: A case report. 61
30666704 2019
24
Eosinophilic pustular folliculitis of infancy suppressed with cetirizine. 61
30791150 2019
25
An aggressive case of granulomatous eosinophilic pustular folliculitis on the face. 61
30847380 2019
26
Thalidomide in the Treatment of Sweet's Syndrome and Eosinophilic Folliculitis Associated With Immune Reconstitution Inflammatory Syndrome. 61
32039221 2019
27
Eosinophilic pustular folliculitis with labial and oral involvement: report of a rare presentation. 61
30677820 2018
28
A case of atypical eosinophilic pustular folliculitis that emerged following the administration of capecitabine. 61
29444365 2018
29
Eosinophilic pustular folliculitis with underlying mantle cell lymphoma. 61
30063774 2018
30
Skin lesions in Aubrac cows strongly associated with fly bites (Haematobia irritans). 61
29498111 2018
31
Acneiform eruptions caused by vitamin B12: A report of five cases and review of the literature. 61
28594082 2018
32
Creeping eruption and eosinophilic folliculitis: Atypical cutaneous larva migrans. 61
29328517 2018
33
A study of clinicopathological correlation of pruritic papular eruptions in HIV patients. 61
30187026 2018
34
Eosinophilic Pustular Folliculitis Associated with Cutaneous Angiosarcoma. 61
29271395 2018
35
Classic form of eosinophilic pustular folliculitis in an immunocompetent girl: rapid and complete resolution after low-dose oral indomethacin treatment. 61
29447640 2017
36
[Acute skin infections and their imitators in children : A photo quiz]. 61
28914333 2017
37
Inflammatory dermatoses in human immunodeficiency virus. 61
30148263 2017
38
Eosinophilic folliculitis in association with chronic lymphocytic leukemia: A clinicopathologic series. 61
28580413 2017
39
Eosinophilic Pustular Folliculitis in Children after Stem Cell Transplantation: An Eruption Distinct from Graft-Versus-Host Disease. 61
28317161 2017
40
Pilosebaceous targeting by isotretenoin-loaded invasomal gel for the treatment of eosinophilic pustular folliculitis: optimization, efficacy and cellular analysis. 61
27649797 2017
41
Necrotizing eosinophilic folliculitis: a new manifestation of the atopic diathesis? 61
27910130 2017
42
Eosinophilic pustular folliculitis: A proposal of diagnostic and therapeutic algorithms. 61
27028427 2016
43
Ofuji's disease in an immunocompetent patient successfully treated with dapsone. 61
27730038 2016
44
Ofuji disease: a rare dermatosis and its challenging therapeutic approach. 61
27828641 2016
45
Eosinophilic pustular folliculitis: A published work-based comprehensive analysis of therapeutic responsiveness. 61
26875627 2016
46
Eosinophilic pustular folliculitis: Trends in therapeutic options. 61
26876326 2016
47
Case of generalized eosinophilic pustular folliculitis induced by allopurinol. 61
26666426 2016
48
Eosinophilic pustular folliculitis associated with hematological disorders: A report of two cases and review of Japanese literature. 61
26362415 2016
49
Eosinophilic pustular folliculitis in a patient with mycosis fungoides. 61
25678045 2016
50
Eosinophilic Skin Diseases: A Comprehensive Review. 61
25876839 2016

Variations for Eosinophilic Pustular Folliculitis

Expression for Eosinophilic Pustular Folliculitis

Search GEO for disease gene expression data for Eosinophilic Pustular Folliculitis.

Pathways for Eosinophilic Pustular Folliculitis

Pathways related to Eosinophilic Pustular Folliculitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.02 PTGDR2 IFNG
2 10.53 PTGDR2 IFNG

GO Terms for Eosinophilic Pustular Folliculitis

Biological processes related to Eosinophilic Pustular Folliculitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 8.62 PTGDR2 IFNG

Sources for Eosinophilic Pustular Folliculitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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