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EPF
MCID: ESN016
MIFTS: 25

Eosinophilic Pustular Folliculitis (EPF)

Categories: Immune diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Eosinophilic Pustular Folliculitis

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MalaCards integrated aliases for Eosinophilic Pustular Folliculitis:

Name: Eosinophilic Pustular Folliculitis 52 71
Eosinophilic Folliculitis 52 71
Eosinophilic Folliculitis, Pustular 52
Ofuji's Disease 52
Ofuji Disease 52
Epf 52

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Immune diseases
See all MalaCards categories (disease lists)


External Ids:

UMLS 71 C0406305 C0744066
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Summaries for Eosinophilic Pustular Folliculitis

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NIH Rare Diseases : 52 Eosinophilic pustular folliculitis (EPF) is a skin disorder characterized by recurring itchy, red or skin-colored bumps and pustules (bumps containing pus). The condition is named after the fact that skin biopsies of this disorder find eosinophils (a type of immune cell ) around hair follicles. The papules mostly appear on the face, scalp, neck and trunk and may persist for weeks or months. EPF affects males more than females. There are several variants of EPF including classic eosinophilic pustular folliculitis (mainly occurring in adults in Japan); HIV-associated EPF, also referred to as immunosuppression-associated EPF; and infantile EPF (with onset from birth or within the first year of life). Whether these are distinct disorders rather than variants of one disorder is controversial, partly because the underlying cause of EFP is not known. Several treatments have been described with variable results, including various oral or topical medications and phototherapy . In patients with HIV-associated disease, antiretroviral therapy tends to greatly diminish symptoms or even eliminate the condition.

MalaCards based summary : Eosinophilic Pustular Folliculitis, also known as eosinophilic folliculitis, is related to folliculitis and dermatitis, atopic. An important gene associated with Eosinophilic Pustular Folliculitis is IFNG (Interferon Gamma), and among its related pathways/superpathways are Hematopoietic Stem Cells and Lineage-specific Markers and Innate Lymphoid Cells Differentiation. Affiliated tissues include skin, bone marrow and bone.

Wikipedia : 74 Eosinophilic folliculitis is an itchy rash with an unknown cause that is most common among individuals... more...

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Related Diseases for Eosinophilic Pustular Folliculitis

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Diseases related to Eosinophilic Pustular Folliculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Related Disease Score Top Affiliating Genes
1 folliculitis 31.3 PTGDR2 IFNG
2 dermatitis, atopic 29.3 PTGDR2 IFNG
3 hypereosinophilic syndrome 10.8
4 acquired immunodeficiency syndrome 10.5
5 immune deficiency disease 10.5
6 exanthem 10.5
7 lymphoma 10.5
8 skin disease 10.5
9 dermatophytosis 10.5
10 exophthalmos 10.5
11 follicular mucinosis 10.4
12 human immunodeficiency virus type 1 10.4
13 allergic hypersensitivity disease 10.4
14 neurofibromatosis, type ii 10.3
15 mycosis fungoides 10.3
16 mantle cell lymphoma 10.3
17 cellulitis 10.3
18 scabies 10.3
19 wells syndrome 10.3
20 annular erythema 10.1
21 basal cell nevus syndrome 10.1
22 dowling-degos disease 1 10.1
23 lymphoma, hodgkin, classic 10.1
24 polycythemia vera 10.1
25 cervical cancer 10.1
26 langerhans cell histiocytosis 10.1
27 lymphoma, non-hodgkin, familial 10.1
28 allergic rhinitis 10.1
29 hepatitis c virus 10.1
30 myelodysplastic syndrome 10.1
31 graft-versus-host disease 10.1
32 angiosarcoma 10.1
33 erythema multiforme 10.1
34 cutaneous t cell lymphoma 10.1
35 drug allergy 10.1
36 lymphoproliferative syndrome 10.1
37 gout 10.1
38 dermatomycosis 10.1
39 hepatitis c 10.1
40 myeloproliferative neoplasm 10.1
41 basal cell carcinoma 10.1
42 acrodermatitis 10.1
43 skin atrophy 10.1
44 histiocytosis 10.1
45 hypertrichosis 10.1
46 pyoderma 10.1
47 rhinitis 10.1
48 eosinophilic pneumonia 10.1
49 polycythemia 10.1
50 rosacea 10.1

Graphical network of the top 20 diseases related to Eosinophilic Pustular Folliculitis:



Diseases related to Eosinophilic Pustular Folliculitis
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Symptoms & Phenotypes for Eosinophilic Pustular Folliculitis

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Drugs & Therapeutics for Eosinophilic Pustular Folliculitis

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Search Clinical Trials , NIH Clinical Center for Eosinophilic Pustular Folliculitis

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Genetic Tests for Eosinophilic Pustular Folliculitis

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Anatomical Context for Eosinophilic Pustular Folliculitis

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MalaCards organs/tissues related to Eosinophilic Pustular Folliculitis:

40
Skin, Bone Marrow, Bone, Testes, Neutrophil, B Cells
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Publications for Eosinophilic Pustular Folliculitis

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Articles related to Eosinophilic Pustular Folliculitis:

(show top 50) (show all 323)
# Title Authors PMID Year
1
Eosinophilic pustular folliculitis on the vulva of a patient with cervical cancer. 61
32173885 2020
2
Eosinophilic Dermatoses: Recognition and Management. 61
32394361 2020
3
Association between eosinophilic folliculitis and follicular mucinosis. A case series. 61
32323302 2020
4
Eosinophilic folliculitis of the scalp associated with PD-1/PDL1 inhibitors. 61
32281235 2020
5
Upregulation of IL-36 cytokines in folliculitis and eosinophilic pustular folliculitis. 61
31424098 2020
6
Suspected eosinophilic pustular folliculitis presenting as rapidly evolving acneiform eruption. 61
31444983 2020
7
Malassezia (Pityrosporum) Folliculitis Incognito: Malessezia-associated Folliculitis Masked by Topical Corticosteroid Therapy. 61
32038889 2020
8
[SYSTEMIC REVIEW OF EOSINOPHILIC DERMATOSES PATIENTS TREATED WITH TNF-Α INHIBITORS AND USTEKINUMAB]. 61
31930806 2020
9
Possible roles of basophils in chronic itch. 61
29894005 2019
10
Eosinophilic dermatoses. 61
31562692 2019
11
Eosinophilic folliculitis in a patient with chronic myelomonocytic leukemia. 61
31388531 2019
12
High accuracy of recognition of common forms of folliculitis by dermoscopy: An observational study. 61
30914342 2019
13
Eosinophilic pustular folliculitis of infancy suppressed with cetirizine. 61
30791150 2019
14
Facial pustules due to drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms may histopathologically mimic eosinophilic pustular folliculitis: A case report. 61
30666704 2019
15
An aggressive case of granulomatous eosinophilic pustular folliculitis on the face. 61
30847380 2019
16
Thalidomide in the Treatment of Sweet's Syndrome and Eosinophilic Folliculitis Associated With Immune Reconstitution Inflammatory Syndrome. 61
32039221 2019
17
Eosinophilic pustular folliculitis with labial and oral involvement: report of a rare presentation. 61
30677820 2018
18
A case of atypical eosinophilic pustular folliculitis that emerged following the administration of capecitabine. 61
29444365 2018
19
Eosinophilic pustular folliculitis with underlying mantle cell lymphoma. 61
30063774 2018
20
Skin lesions in Aubrac cows strongly associated with fly bites (Haematobia irritans). 61
29498111 2018
21
Acneiform eruptions caused by vitamin B12: A report of five cases and review of the literature. 61
28594082 2018
22
Creeping eruption and eosinophilic folliculitis: Atypical cutaneous larva migrans. 61
29328517 2018
23
Eosinophilic Pustular Folliculitis Associated with Cutaneous Angiosarcoma. 61
29271395 2018
24
A study of clinicopathological correlation of pruritic papular eruptions in HIV patients. 61
30187026 2018
25
Classic form of eosinophilic pustular folliculitis in an immunocompetent girl: rapid and complete resolution after low-dose oral indomethacin treatment. 61
29447640 2017
26
[Acute skin infections and their imitators in children : A photo quiz]. 61
28914333 2017
27
Inflammatory dermatoses in human immunodeficiency virus. 61
30148263 2017
28
Eosinophilic folliculitis in association with chronic lymphocytic leukemia: A clinicopathologic series. 61
28580413 2017
29
Eosinophilic Pustular Folliculitis in Children after Stem Cell Transplantation: An Eruption Distinct from Graft-Versus-Host Disease. 61
28317161 2017
30
Pilosebaceous targeting by isotretenoin-loaded invasomal gel for the treatment of eosinophilic pustular folliculitis: optimization, efficacy and cellular analysis. 61
27649797 2017
31
Necrotizing eosinophilic folliculitis: a new manifestation of the atopic diathesis? 61
27910130 2017
32
Eosinophilic pustular folliculitis: A proposal of diagnostic and therapeutic algorithms. 61
27028427 2016
33
Ofuji's disease in an immunocompetent patient successfully treated with dapsone. 61
27730038 2016
34
Ofuji disease: a rare dermatosis and its challenging therapeutic approach. 61
27828641 2016
35
Eosinophilic pustular folliculitis: A published work-based comprehensive analysis of therapeutic responsiveness. 61
26875627 2016
36
Eosinophilic pustular folliculitis: Trends in therapeutic options. 61
26876326 2016
37
Eosinophilic pustular folliculitis associated with hematological disorders: A report of two cases and review of Japanese literature. 61
26362415 2016
38
Eosinophilic Skin Diseases: A Comprehensive Review. 61
25876839 2016
39
Eosinophilic pustular folliculitis in a patient with mycosis fungoides. 61
25678045 2016
40
Case of generalized eosinophilic pustular folliculitis induced by allopurinol. 61
26666426 2016
41
Two cases of eosinophilic pustular folliculitis associated with pregnancy. 61
26499866 2016
42
Eosinophilic Pustular Folliculitis Post Chemotherapy in a Patient of Non-Hogkins Lymphoma: A Case Report. 61
26538725 2015
43
Vesicles and pustules on the fingers as an initial manifestation of eosinophilic pustular folliculitis. 61
26011016 2015
44
Eosinophilic pustular folliculitis with extensive distribution: correlation of serum TARC levels and peripheral blood eosinophil numbers. 61
24697527 2015
45
Generalized Eosinophilic Pustular Folliculitis of Infancy Responding to Hydroxyzine. 61
26273169 2015
46
Eosinophilic folliculitis occurring after stem cell transplant for acute lymphoblastic leukemia: a case report and review. 61
25039354 2015
47
Eosinophilic follicular reaction induced by Demodex folliculorum mite: a different disease from eosinophilic folliculitis. 61
25623943 2015
48
Eosinophilic pustular folliculitis: the transition in sex differences and interracial characteristics between 1965 and 2013. 61
25675987 2015
49
Eosinophilic pustular folliculitis clinically presenting as orofacial granuloma: successful treatment with indomethacin, but not ibuprofen. 61
24979363 2015
50
Hyperimmunoglobulin E syndrome presenting as eosinophilic pustular folliculitis: a case report. 61
24739054 2015
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Variations for Eosinophilic Pustular Folliculitis

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Expression for Eosinophilic Pustular Folliculitis

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Search GEO for disease gene expression data for Eosinophilic Pustular Folliculitis.
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Pathways for Eosinophilic Pustular Folliculitis

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Pathways related to Eosinophilic Pustular Folliculitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Hematopoietic Stem Cells and Lineage-specific Markers 64
11.02 PTGDR2 IFNG
2
Innate Lymphoid Cells Differentiation 64
10.53 PTGDR2 IFNG
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GO Terms for Eosinophilic Pustular Folliculitis

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Biological processes related to Eosinophilic Pustular Folliculitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 8.62 PTGDR2 IFNG
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Sources for Eosinophilic Pustular Folliculitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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