MCID: ESN016
MIFTS: 28

Eosinophilic Pustular Folliculitis

Categories: Immune diseases, Rare diseases

Aliases & Classifications for Eosinophilic Pustular Folliculitis

MalaCards integrated aliases for Eosinophilic Pustular Folliculitis:

Name: Eosinophilic Pustular Folliculitis 54 74
Eosinophilic Folliculitis 54 74
Eosinophilic Folliculitis, Pustular 54
Ofuji's Disease 54
Ofuji Disease 54
Epf 54

Classifications:



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Summaries for Eosinophilic Pustular Folliculitis

NIH Rare Diseases : 54 Eosinophilic pustular folliculitis (EPF) is a skin disorder characterized by recurring itchy, red or skin-colored bumps and pustules (bumps containing pus). The condition is named after the fact that skin biopsies of this disorder find eosinophils (a type of immune cell) around hair follicles. The papules mostly appear on the face, scalp, neck and trunk and may persist for weeks or months. EPF affects males more than females. There are several variants of EPF including classic eosinophilic pustular folliculitis (mainly occurring in adults in Japan); HIV-associated EPF, also referred to as immunosuppression-associated EPF; and infantile EPF (with onset from birth or within the first year of life). Whether these are distinct disorders rather than variants of one disorder is controversial, partly because the underlying cause of EFP is not known. Several treatments have been described with variable results, including various oral or topical medications and phototherapy. In patients with HIV-associated disease, antiretroviral therapy tends to greatly diminish symptoms or even eliminate the condition.

MalaCards based summary : Eosinophilic Pustular Folliculitis, also known as eosinophilic folliculitis, is related to folliculitis and lymphoma. An important gene associated with Eosinophilic Pustular Folliculitis is IFNG (Interferon Gamma), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Lymphoid Cell Differentiation Pathways. Affiliated tissues include skin, bone and b cells.

Wikipedia : 77 Eosinophilic folliculitis is an itchy rash with an unknown cause that is most common among individuals... more...

Related Diseases for Eosinophilic Pustular Folliculitis

Diseases related to Eosinophilic Pustular Folliculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 folliculitis 31.4 IFNG PTGDR2
2 lymphoma 10.3
3 acquired immunodeficiency syndrome 10.3
4 hypereosinophilic syndrome 10.3
5 cellulitis 10.2
6 follicular mucinosis 10.2
7 wells syndrome 10.2
8 hepatocellular carcinoma 10.1
9 basal cell nevus syndrome 10.1
10 lymphoma, hodgkin, classic 10.1
11 mycosis fungoides 10.1
12 polycythemia vera 10.1
13 lymphoma, non-hodgkin, familial 10.1
14 basal cell carcinoma 1 10.1
15 human immunodeficiency virus type 1 10.1
16 hepatitis c virus 10.1
17 myelodysplastic syndrome 10.1
18 graft-versus-host disease 10.1
19 hepatitis 10.1
20 mantle cell lymphoma 10.1
21 angiosarcoma 10.1
22 allergic hypersensitivity disease 10.1
23 hepatitis c 10.1
24 basal cell carcinoma 10.1
25 polycythemia 10.1
26 sezary's disease 10.1
27 dermatophytosis 10.1
28 pulmonary eosinophilia 10.1
29 drug reaction with eosinophilia and systemic symptoms 10.1
30 leukemia 10.1
31 lymphocytic leukemia 10.1
32 alopecia 10.0
33 leukemia, chronic lymphocytic 2 9.9
34 leukemia, chronic lymphocytic 9.9
35 leukemia, acute lymphoblastic 9.9
36 strongyloidiasis 9.9
37 human immunodeficiency virus infectious disease 9.9
38 toxocariasis 9.9
39 cutaneous larva migrans 9.9
40 leukemia, b-cell, chronic 9.9
41 allergic conjunctivitis 9.7 IFNG PTGDR2
42 upper respiratory tract disease 9.7 IFNG PTGDR2
43 dermatitis, atopic 9.6 IFNG PTGDR2
44 asthma 9.5 IFNG PTGDR2

Graphical network of the top 20 diseases related to Eosinophilic Pustular Folliculitis:



Diseases related to Eosinophilic Pustular Folliculitis

Symptoms & Phenotypes for Eosinophilic Pustular Folliculitis

Drugs & Therapeutics for Eosinophilic Pustular Folliculitis

Search Clinical Trials , NIH Clinical Center for Eosinophilic Pustular Folliculitis

Genetic Tests for Eosinophilic Pustular Folliculitis

Anatomical Context for Eosinophilic Pustular Folliculitis

MalaCards organs/tissues related to Eosinophilic Pustular Folliculitis:

42
Skin, Bone, B Cells, Bone Marrow, Testes, Neutrophil

Publications for Eosinophilic Pustular Folliculitis

Articles related to Eosinophilic Pustular Folliculitis:

(show top 50) (show all 217)
# Title Authors Year
1
Facial pustules due to drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms may histopathologically mimic eosinophilic pustular folliculitis: A case report. ( 30666704 )
2019
2
Eosinophilic pustular folliculitis of infancy suppressed with cetirizine. ( 30791150 )
2019
3
An aggressive case of granulomatous eosinophilic pustular folliculitis on the face. ( 30847380 )
2019
4
Eosinophilic Pustular Folliculitis Associated with Cutaneous Angiosarcoma. ( 29271395 )
2018
5
Creeping eruption and eosinophilic folliculitis: Atypical cutaneous larva migrans. ( 29328517 )
2018
6
A case of atypical eosinophilic pustular folliculitis that emerged following the administration of capecitabine. ( 29444365 )
2018
7
Eosinophilic pustular folliculitis with underlying mantle cell lymphoma. ( 30063774 )
2018
8
Eosinophilic pustular folliculitis with labial and oral involvement: report of a rare presentation. ( 30677820 )
2018
9
Pilosebaceous targeting by isotretenoin-loaded invasomal gel for the treatment of eosinophilic pustular folliculitis: optimization, efficacy and cellular analysis. ( 27649797 )
2017
10
Eosinophilic Pustular Folliculitis in Children after Stem Cell Transplantation: An Eruption Distinct from Graft-Versus-Host Disease. ( 28317161 )
2017
11
Classic form of eosinophilic pustular folliculitis in an immunocompetent girl: rapid and complete resolution after low-dose oral indomethacin treatment. ( 29447640 )
2017
12
Necrotizing eosinophilic folliculitis: a new manifestation of the atopic diathesis? ( 27910130 )
2017
13
Eosinophilic folliculitis in association with chronic lymphocytic leukemia: A clinicopathologic series. ( 28580413 )
2017
14
Eosinophilic pustular folliculitis in a patient with mycosis fungoides. ( 25678045 )
2016
15
Eosinophilic pustular folliculitis associated with hematological disorders: A report of two cases and review of Japanese literature. ( 26362415 )
2016
16
Two cases of eosinophilic pustular folliculitis associated with pregnancy. ( 26499866 )
2016
17
Case of generalized eosinophilic pustular folliculitis induced by allopurinol. ( 26666426 )
2016
18
Eosinophilic pustular folliculitis: A published work-based comprehensive analysis of therapeutic responsiveness. ( 26875627 )
2016
19
Eosinophilic pustular folliculitis: Trends in therapeutic options. ( 26876326 )
2016
20
Eosinophilic pustular folliculitis: A proposal of diagnostic and therapeutic algorithms. ( 27028427 )
2016
21
Eosinophilic pustular folliculitis with extensive distribution: correlation of serum TARC levels and peripheral blood eosinophil numbers. ( 24697527 )
2015
22
Hyperimmunoglobulin E syndrome presenting as eosinophilic pustular folliculitis: a case report. ( 24739054 )
2015
23
Eosinophilic pustular folliculitis clinically presenting as orofacial granuloma: successful treatment with indomethacin, but not ibuprofen. ( 24979363 )
2015
24
Clinical epidemiology of eosinophilic pustular folliculitis: results from a nationwide survey in Japan. ( 25503295 )
2015
25
Eosinophilic pustular folliculitis: the transition in sex differences and interracial characteristics between 1965 and 2013. ( 25675987 )
2015
26
Vesicles and pustules on the fingers as an initial manifestation of eosinophilic pustular folliculitis. ( 26011016 )
2015
27
Generalized Eosinophilic Pustular Folliculitis of Infancy Responding to Hydroxyzine. ( 26273169 )
2015
28
Eosinophilic Pustular Folliculitis Post Chemotherapy in a Patient of Non-Hogkins Lymphoma: A Case Report. ( 26538725 )
2015
29
Eosinophilic folliculitis occurring after stem cell transplant for acute lymphoblastic leukemia: a case report and review. ( 25039354 )
2015
30
Eosinophilic follicular reaction induced by Demodex folliculorum mite: a different disease from eosinophilic folliculitis. ( 25623943 )
2015
31
Induction of CD163(+) M2 macrophages in the lesional skin of eosinophilic pustular folliculitis. ( 23604082 )
2014
32
Facial and extrafacial eosinophilic pustular folliculitis: a clinical and histopathological comparative study. ( 24341854 )
2014
33
Infantile case of eosinophilic pustular folliculitis successfully treated with topical indomethacin. ( 24433329 )
2014
34
Eosinophilic pustular folliculitis associated with Sézary syndrome. ( 24708187 )
2014
35
Widespread eosinophilic pustular folliculitis in a nonimmunocompromised patient. ( 24751524 )
2014
36
Eosinophilic pustular folliculitis: association with long-term immunosuppressant use in a solid organ transplant recipient. ( 25143686 )
2014
37
Refractory eosinophilic pustular folliculitis resistant to oral indomethacin successfully treated with adjuvant topical indomethacin. ( 25182296 )
2014
38
Acrosyringeal involvement of palmoplantar lesions of eosinophilic pustular folliculitis. ( 22504923 )
2013
39
Eosinophilic pustular folliculitis of infancy: a series of 15 cases and review of the literature. ( 22819356 )
2013
40
Eosinophilic pustular folliculitis: a review of the Japanese published works. ( 23083212 )
2013
41
Eosinophilic pustular folliculitis involving labial mucosa, which improved with naproxen. ( 23463836 )
2013
42
Clinical and histopathological differential diagnosis of eosinophilic pustular folliculitis. ( 23488969 )
2013
43
Indomethacin for refractory infantile eosinophilic pustular folliculitis. ( 23552848 )
2013
44
Indomethacin inhibits eosinophil migration to prostaglandin D2 : therapeutic potential of CRTH2 desensitization for eosinophilic pustular folliculitis. ( 23582181 )
2013
45
Evaluation of the Effectiveness of Antibiotics against Eosinophilic Pustular Folliculitis. ( 23741214 )
2013
46
Transdermal nicotine patches for eosinophilic pustular folliculitis. ( 23802575 )
2013
47
Intractable erythematous plaques on the hands: palmoplantar eosinophilic pustular folliculitis. ( 24073908 )
2013
48
Immunosuppression-associated eosinophilic pustular folliculitis (IS-EPF) developing after Highly Active Anti-Retroviral Therapy (HAART): the possible mechanisms through CD163+ M2 macrophages. ( 24213586 )
2013
49
Extended eosinophilic pustular folliculitis with reactive bone marrow hypereosinophilia responsive to combined treatment with indomethacin, dapsone, and narrow-band UVB phototherapy. ( 24238194 )
2013
50
Analysis of serum chemokine levels in patients with HIV-associated eosinophilic folliculitis. ( 22672135 )
2013

Variations for Eosinophilic Pustular Folliculitis

Expression for Eosinophilic Pustular Folliculitis

Search GEO for disease gene expression data for Eosinophilic Pustular Folliculitis.

Pathways for Eosinophilic Pustular Folliculitis

Pathways related to Eosinophilic Pustular Folliculitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.02 IFNG PTGDR2
2 10.53 IFNG PTGDR2

GO Terms for Eosinophilic Pustular Folliculitis

Biological processes related to Eosinophilic Pustular Folliculitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 8.62 IFNG PTGDR2

Sources for Eosinophilic Pustular Folliculitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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