MCID: EPN001
MIFTS: 46

Ependymoblastoma

Categories: Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Ependymoblastoma

MalaCards integrated aliases for Ependymoblastoma:

Name: Ependymoblastoma 12 76 59 55 15 73

Characteristics:

Orphanet epidemiological data:

59
ependymoblastoma
Inheritance: Not applicable; Age of onset: Infancy,Neonatal;

Classifications:

Orphanet: 59  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:4794
MeSH 44 D018242
NCIt 50 C4915
SNOMED-CT 68 21589007
Orphanet 59 ORPHA251880
UMLS via Orphanet 74 C0700367
ICD10 via Orphanet 34 C71.9
UMLS 73 C0700367

Summaries for Ependymoblastoma

MalaCards based summary : Ependymoblastoma is related to medulloepithelioma and ependymoma, and has symptoms including vomiting and headache. An important gene associated with Ependymoblastoma is NES (Nestin), and among its related pathways/superpathways are Development HGF signaling pathway and MicroRNAs in cancer. The drugs Cisplatin and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and bone, and related phenotypes are behavior/neurological and cardiovascular system

Wikipedia : 76 Primitive neuroectodermal tumor (PNET) is a malignant (cancerous) neural crest tumor. It is a rare... more...

Related Diseases for Ependymoblastoma

Diseases in the Ependymoblastoma family:

Adult Ependymoblastoma

Diseases related to Ependymoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 129)
# Related Disease Score Top Affiliating Genes
1 medulloepithelioma 30.3 GFAP NES VIM
2 ependymoma 30.3 GFAP NES VIM
3 anaplastic ependymoma 30.2 GFAP VIM
4 medulloblastoma 30.0 GFAP NES NGF TP53
5 pediatric infratentorial ependymoblastoma 12.1
6 adult ependymoblastoma 12.1
7 pediatric cerebral ependymoblastoma 12.1
8 embryonal tumor with multilayered rosettes 11.5
9 pediatric supratentorial ependymoma 11.0
10 odontoma 10.2 NES VIM
11 anaplastic ganglioglioma 10.2 GFAP NES
12 central nervous system germ cell tumor 10.1 GFAP NES
13 dysembryoplastic neuroepithelial tumor 10.1 GFAP NES
14 neuronal migration disorders 10.1 NES VIM
15 brain stem cancer 10.1 NES TP53
16 papillary ependymoma 10.1 GFAP NES
17 primitive neuroectodermal tumor of the cervix uteri 10.1 GFAP VIM
18 cutaneous leiomyosarcoma 10.1 GFAP VIM
19 leiomyosarcoma 10.1 TP53 VIM
20 parachordoma 10.1 GFAP VIM
21 subependymoma 10.1 GFAP NES
22 rhabdoid meningioma 10.1 GFAP VIM
23 syringocystadenoma papilliferum 10.1 GFAP VIM
24 chordoid meningioma 10.1 GFAP VIM
25 osteochondroma 10.1 NES VIM
26 clear cell ependymoma 10.1 GFAP VIM
27 tanycytic ependymoma 10.1 GFAP NES
28 clear cell meningioma 10.1 GFAP VIM
29 myxopapillary ependymoma 10.1 GFAP VIM
30 brain ischemia 10.1 GFAP NES
31 spiradenoma 10.1 TP53 VIM
32 melanotic neuroectodermal tumor 10.1 GFAP VIM
33 central neurocytoma 10.1 GFAP NES
34 syringoma 10.1 GFAP VIM
35 angiocentric glioma 10.1 GFAP VIM
36 subependymal giant cell astrocytoma 10.1 GFAP NES
37 endocervical adenocarcinoma 10.1 TP53 VIM
38 glomus tumor 10.1 TP53 VIM
39 granular cell tumor 10.1 GFAP VIM
40 optic nerve neoplasm 10.1 NES TP53
41 osteofibrous dysplasia 10.1 MET VIM
42 embryonal sarcoma 10.1 TP53 VIM
43 frontal convexity meningioma 10.1 GFAP TP53
44 cerebral primitive neuroectodermal tumor 10.1 TP53 VIM
45 liver angiosarcoma 10.1 TP53 VIM
46 gliofibroma 10.1 GFAP TP53
47 retinitis pigmentosa 42 10.1 GFAP NES
48 cerebral convexity meningioma 10.1 GFAP TP53
49 granulosa cell tumor of the ovary 10.1 TP53 VIM
50 cellular ependymoma 10.1 GFAP TP53

Graphical network of the top 20 diseases related to Ependymoblastoma:



Diseases related to Ependymoblastoma

Symptoms & Phenotypes for Ependymoblastoma

UMLS symptoms related to Ependymoblastoma:


vomiting, headache

MGI Mouse Phenotypes related to Ependymoblastoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.85 GFAP LIN28A MET NGF TP53 VIM
2 cardiovascular system MP:0005385 9.8 GFAP LIN28A MET NGF TP53 VIM
3 muscle MP:0005369 9.73 GFAP LIN28A MET NGF TP53 VIM
4 nervous system MP:0003631 9.63 GFAP LIN28A MET NGF TP53 VIM
5 normal MP:0002873 9.35 GFAP LIN28A MET NGF TP53
6 vision/eye MP:0005391 9.02 GFAP MET NGF TP53 VIM

Drugs & Therapeutics for Ependymoblastoma

Drugs for Ependymoblastoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 184)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 3,Phase 2 15663-27-1 2767 441203 84093
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 1177-87-3
3
Ondansetron Approved Phase 3 99614-02-5 4595
4
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
5
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
6
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
7
Donepezil Approved Phase 3,Phase 2 120014-06-4 3152
8
Histamine Approved, Investigational Phase 3 51-45-6, 75614-87-8 774
9
Cyproheptadine Approved Phase 3 129-03-3 2913
10
Methylphenidate Approved, Investigational Phase 3 113-45-1 4158
11
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
12 Pancreatic Polypeptide Investigational Phase 3,Phase 1 59763-91-6
13 Dermatologic Agents Phase 3,Phase 2,Phase 1
14 Gastrointestinal Agents Phase 3,Phase 1,Not Applicable
15 Antiemetics Phase 3,Phase 1
16 Autonomic Agents Phase 3,Phase 1
17 BB 1101 Phase 3,Phase 2,Phase 1
18 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
19 Emetics Phase 3
20 Cola Phase 3,Phase 1
21 Central Nervous System Depressants Phase 3,Phase 2
22 Adjuvants, Anesthesia Phase 3
23 Liver Extracts Phase 3,Phase 1,Phase 2
24 Anesthetics, Intravenous Phase 3
25 Analgesics, Opioid Phase 3
26 Anesthetics, General Phase 3
27 Analgesics Phase 3,Phase 2,Phase 1
28 Narcotics Phase 3
29 Anesthetics Phase 3
30 Neurotransmitter Agents Phase 3,Phase 2
31 Nootropic Agents Phase 3,Phase 2
32 Cholinergic Agents Phase 3,Phase 2
33 Cholinesterase Inhibitors Phase 3,Phase 2
34 Serotonin Agents Phase 3
35 Anti-Allergic Agents Phase 3
36 Serotonin Antagonists Phase 3
37 Histamine H1 Antagonists Phase 3
38
Histamine Phosphate Phase 3 51-74-1 65513
39 Antipruritics Phase 3
40 Histamine Antagonists Phase 3
41 Dexmethylphenidate Hydrochloride Phase 3
42 Neurotransmitter Uptake Inhibitors Phase 3
43 Dopamine Uptake Inhibitors Phase 3
44 Central Nervous System Stimulants Phase 3
45 Dopamine Agents Phase 3
46
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
47
Temozolomide Approved, Investigational Phase 1, Phase 2 85622-93-1 5394
48
Dacarbazine Approved, Investigational Phase 1, Phase 2 4342-03-4 5351166
49
Bevacizumab Approved, Investigational Phase 2 216974-75-3
50 Piracetam Approved, Investigational Phase 2 7491-74-9

Interventional clinical trials:

(show top 50) (show all 55)
# Name Status NCT ID Phase Drugs
1 Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
2 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
3 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
4 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
5 Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors Terminated NCT00031798 Phase 3 methylphenidate hydrochloride
6 Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma Completed NCT01977677 Phase 1, Phase 2 temozolomide;plerixafor
7 Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma Completed NCT00883688 Phase 2 Bevacizumab;Lapatinib
8 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors Completed NCT00629889 Phase 2 levetiracetam;pregabalin
9 Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer Completed NCT00014573 Phase 2 carmustine;cisplatin;cyclophosphamide;paclitaxel
10 Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma Completed NCT00006258 Phase 2 cisplatin;cyclophosphamide;etoposide;methotrexate;vincristine sulfate
11 Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor Completed NCT00070161 Phase 2 donepezil hydrochloride
12 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers Completed NCT00002752 Phase 1, Phase 2
13 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors Completed NCT00003478 Phase 1, Phase 2
14 Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors Recruiting NCT02684071 Phase 2 Intra thecal methotrexate;topotecan;cyclophosphamide
15 Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors Recruiting NCT02095132 Phase 1, Phase 2 Adavosertib;Irinotecan Hydrochloride
16 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
17 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
18 Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors Suspended NCT00983398 Phase 1, Phase 2 Carboplatin;Mannitol;Melphalan;Sodium Thiosulfate
19 Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors Withdrawn NCT00005083 Phase 2
20 Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors Unknown status NCT00002647 Phase 1 verteporfin
21 Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 Completed NCT01082926 Phase 1
22 ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors Completed NCT00946335 Phase 1 veliparib;temozolomide
23 RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma Completed NCT01119599 Phase 1 Gamma-Secretase Inhibitor RO4929097;Temozolomide
24 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
25 Cilengitide in Treating Children With Refractory Primary Brain Tumors Completed NCT00063973 Phase 1 cilengitide
26 Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors Completed NCT00052780 Phase 1 O6-benzylguanine;temozolomide
27 Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors Completed NCT00100880 Phase 1 lenalidomide
28 Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction Completed NCT00030498 Phase 1 erlotinib hydrochloride
29 A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors Completed NCT00784914 Phase 1 temsirolimus
30 Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment Completed NCT00544284 Phase 1 bortezomib;temozolomide
31 Monoclonal Antibody Therapy in Treating Patients With Recurrent Gliomas Completed NCT00002753 Phase 1
32 Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer Completed NCT00006368 Phase 1
33 CC-5013 in Treating Patients With Recurrent Glioma Completed NCT00036894 Phase 1 lenalidomide
34 Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid Tumors Completed NCT00008086 Phase 1 carboplatin
35 Thalidomide and Docetaxel in Treating Patients With Advanced Cancer Completed NCT00049296 Phase 1 docetaxel;thalidomide
36 MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma Completed NCT00020579 Phase 1 entinostat
37 Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas Completed NCT00019019 Phase 1 carboxyamidotriazole;paclitaxel
38 Carmustine in Treating Patients With Recurrent Malignant Glioma Completed NCT00004028 Phase 1 carmustine
39 Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer Completed NCT00003022 Phase 1
40 SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors Recruiting NCT03434262 Phase 1 Gemcitabine;ribociclib;sonidegib;trametinib
41 Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors Recruiting NCT02255461 Phase 1 palbociclib isethionate
42 Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone
43 Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors Terminated NCT00110032 Phase 1 EF5
44 Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma Terminated NCT00003567 Phase 1 O6-benzylguanine;carmustine;temozolomide
45 Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical Trial Completed NCT00890435
46 Study of Blood and Cheek Cell Samples From Patients With Glioma Completed NCT01009307
47 Study of Tissue Samples From Patients With Glioma or Other Brain Tumors Completed NCT00967200
48 Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors Completed NCT00499798
49 Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders Completed NCT00255671
50 Magnetic Resonance Imaging in Determining Extent of Cancer in Patients With Newly Diagnosed Glioma Completed NCT00005082 Not Applicable

Search NIH Clinical Center for Ependymoblastoma

Genetic Tests for Ependymoblastoma

Anatomical Context for Ependymoblastoma

MalaCards organs/tissues related to Ependymoblastoma:

41
Brain, Liver, Bone, Spinal Cord, Breast, Ovary, Thyroid

Publications for Ependymoblastoma

Articles related to Ependymoblastoma:

(show top 50) (show all 61)
# Title Authors Year
1
A Congenital Case of Ependymoblastoma: A Rare and Aggressive Brain Tumor. ( 29432310 )
2018
2
Lymph node metastasis of presacral ependymoblastoma in a young child. ( 28215462 )
2017
3
Posterior fossa ependymoblastoma diagnosed in the second month of life: uneventful 12A years survival after gross total resection followed by chemotherapy. ( 26251773 )
2015
4
Sacrococcygeal ependymoblastoma. ( 26493054 )
2015
5
Systematic comparison of MRI findings in pediatric ependymoblastoma with ependymoma and CNS primitive neuroectodermal tumor not otherwise specified. ( 25916887 )
2015
6
MRI characteristics of ependymoblastoma: results from 22 centrally reviewed cases. ( 24948504 )
2014
7
Ependymoblastoma of the brainstem: MRI findings and differential diagnosis. ( 24464920 )
2014
8
MET T992I mutation in a case of ependymoblastoma/embryonal tumour with multilayered rosettes. ( 25194039 )
2014
9
Ependymoblastoma with cystic change in a child. ( 24724717 )
2014
10
A case report of an ependymoblastoma in the rectovaginal space and a review of the literature. ( 24511018 )
2014
11
Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity. ( 24337497 )
2013
12
[Are the medulloepithelioma, ependymoblastoma and embryonal tumor with multilayered rosettes the same entity?]. ( 24558755 )
2013
13
Outcome of 11 children with ependymoblastoma treated within the prospective HIT-trials between 1991 and 2006. ( 21308398 )
2011
14
Ependymoblastoma in an adult: a diagnostic challenge on cytology. ( 22674109 )
2011
15
Ependymoblastoma: dear, damned, distracting diagnosis, farewell!*. ( 19120373 )
2010
16
Ependymoblastoma in a Japanese Black heifer. ( 19887749 )
2009
17
Congenital ependymoblastoma arising in the sacrococcygeal soft tissue: a case study. ( 18402386 )
2008
18
Divergent ependymal tumor (ependymoblastoma/anaplastic ependymoma) of the posterior fossa: an uncommon case observed in a child. ( 18827270 )
2008
19
Tumor suppressor proteins are differentially affected in human ependymoblastoma and medulloblastoma cells exposed to nerve growth factor. ( 17453820 )
2007
20
In vitro human ependymoblastoma cells differentiate after exposure to nerve growth factor. ( 15906158 )
2004
21
Ependymoblastoma: a clinical review. ( 8570066 )
1995
22
Ependymoblastoma: MR presentation. A case report and review of the literature. ( 7491192 )
1995
23
Ependymoblastoma in an HIV-positive hemophilic girl. ( 8084312 )
1994
24
Tentorial traversal by ependymoblastoma. ( 1899507 )
1991
25
Limits of tumour treatment follow up by surface coil 31P magnetic resonance spectroscopy. The case of sarcosinamide-CNU treated ependymoblastoma. ( 2484278 )
1989
26
Ependymoblastoma: a histological, immunohistological and ultrastructural study of five cases. ( 3286469 )
1988
27
Congenital ependymoblastoma presenting as a sacrococcygeal mass in a newborn: an immunohistochemical, light and electron microscopic study. ( 3308267 )
1987
28
The expression and detection of MHC class I antigens on murine neuroblastoma and ependymoblastoma lines. ( 3492512 )
1987
29
The ultrastructure of the ependymoblastoma. ( 3776467 )
1986
30
Primary leptomeningeal ependymoblastoma. Case report. ( 3701447 )
1986
31
Primary intracranial ependymoblastoma presenting as spinal cord compression due to metastasis. ( 3829033 )
1986
32
Ependymoblastoma. A reappraisal of a rare embryonal tumor. ( 3978547 )
1985
33
Ependymoblastoma associated with prenatal exposure to diphenylhydantoin and methylphenobarbitone. ( 3978571 )
1985
34
Ependymoblastoma in a dairy calf. ( 6485211 )
1984
35
The murine ependymoblastoma: growth pattern and survival in C57Bl/6J mice. ( 6861007 )
1983
36
Inhibition of RNA synthesis in murine ependymoblastoma by the combination of amphotericin B and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. ( 7471107 )
1980
37
Congenital ependymoblastoma. ( 7188822 )
1980
38
Synergistic effect of combined hyperthermia and a nitrosourea in treatment of a murine ependymoblastoma. ( 7388821 )
1980
39
Nonspecific inhibition of tumor growth in the central nervous system: observations of intracerebral ependymoblastoma in mice with chronic Toxoplasma infection. ( 894752 )
1977
40
Isolation of plasma membranes from murine ependymoblastoma and subcellular distribution of amphotericin B in this tumor. ( 851531 )
1977
41
Transplantation resistance to mouse ependymoblastoma following immunization with dehistonized syngeneic tumor chromatin. ( 1268848 )
1976
42
Potentiation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea by amphotericin B in murine ependymoblastoma. ( 975049 )
1976
43
Increased survival of mouse ependymoblastoma hosts previously treated with dehistonized tumor chromatin. ( 1153860 )
1975
44
An ependymoblastoma of the pons. ( 1159567 )
1975
45
A mouse ependymoblastoma as an experimental model for screening potential antineoplastic drugs. ( 4447935 )
1974
46
Recent experience with intrathecal radiogold for medulloblastoma and ependymoblastoma: a progress report. ( 4479529 )
1974
47
The fine structure of ependymoblastoma. ( 4685709 )
1973
48
Shortcomings of 99m Tc-pertechnetate as a tracer for brain tumor detection as shown by well counting of human brain tumors and a mouse ependymoblastoma. ( 4336247 )
1972
49
Chemotherapy of brain tumors. Uptake of tritiated methotrexate by a transplantable intracerebral ependymoblastoma in mice. ( 5037043 )
1972
50
The uptake of hydrocortisone in mouse brain and ependymoblastoma. ( 5008732 )
1972

Variations for Ependymoblastoma

Expression for Ependymoblastoma

Search GEO for disease gene expression data for Ependymoblastoma.

Pathways for Ependymoblastoma

Pathways related to Ependymoblastoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.28 MET NGF TP53
2 12.02 MET TP53 VIM
3
Show member pathways
11.79 MET NGF TP53
4 11.51 GFAP TP53 VIM
5 11.38 LIN28A MET NES VIM
6
Show member pathways
11.37 GFAP NES VIM
7
Show member pathways
11.28 NGF TP53
8 11.25 MET TP53
9 10.82 GFAP NES NGF VIM
10 10.53 GFAP MET NGF VIM

GO Terms for Ependymoblastoma

Cellular components related to Ependymoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 9.16 GFAP NES
2 polysome GO:0005844 8.96 LIN28A VIM
3 intermediate filament GO:0005882 8.8 GFAP NES VIM

Biological processes related to Ependymoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.58 NGF TP53 VIM
2 negative regulation of neuron projection development GO:0010977 9.37 GFAP VIM
3 intermediate filament organization GO:0045109 9.32 GFAP VIM
4 astrocyte development GO:0014002 9.26 GFAP VIM
5 positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800 9.16 LIN28A TP53
6 Bergmann glial cell differentiation GO:0060020 8.96 GFAP VIM
7 intermediate filament-based process GO:0045103 8.62 GFAP VIM

Molecular functions related to Ependymoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.26 GFAP MET TP53 VIM
2 structural molecule activity GO:0005198 8.8 GFAP NES VIM

Sources for Ependymoblastoma

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