MCID: EPC001
MIFTS: 23

Epicardium Cancer

Categories: Cancer diseases, Cardiovascular diseases

Aliases & Classifications for Epicardium Cancer

MalaCards integrated aliases for Epicardium Cancer:

Name: Epicardium Cancer 12 15
Malignant Neoplasm of Epicardium 12 70
Malignant Epicardial Tumor 12
Neoplasm of Epicardium 70
Epicardial Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4699
NCIt 50 C5347
SNOMED-CT 67 126733004 93782004
UMLS 70 C0346610 C1290403 C2607932

Summaries for Epicardium Cancer

MalaCards based summary : Epicardium Cancer, also known as malignant neoplasm of epicardium, is related to blood group incompatibility and thiopurines, poor metabolism of, 1. An important gene associated with Epicardium Cancer is TNNI3 (Troponin I3, Cardiac Type), and among its related pathways/superpathways are Biosynthesis of cofactors and Porphyrin and chlorophyll metabolism.

Related Diseases for Epicardium Cancer

Graphical network of the top 20 diseases related to Epicardium Cancer:



Diseases related to Epicardium Cancer

Symptoms & Phenotypes for Epicardium Cancer

Drugs & Therapeutics for Epicardium Cancer

Search Clinical Trials , NIH Clinical Center for Epicardium Cancer

Genetic Tests for Epicardium Cancer

Anatomical Context for Epicardium Cancer

Publications for Epicardium Cancer

Articles related to Epicardium Cancer:

# Title Authors PMID Year
1
A Rare Case of Sarcoidosis-Induced Polyserositis and Steroid-Induced Mediastinal Lipomatosis Masquerading as an Epicardial Tumor. 61
32577599 2020
2
Metastatic Epicardial Leiomyoma with uncertain malignant potential. 61
29423163 2017
3
Cardiac epicardial tumor with coronary artery compression. 61
19084423 2009
4
Postmortem cardiac troponin-I levels predict intramyocardial damage at autopsy. 61
18064406 2008
5
A 25-year-old woman with a gastric GIST and a PET-positive epicardial tumor. 61
17327860 2007
6
Primary cardiac liposarcoma causing cardiac tamponade: report of a case. 61
17952529 2007
7
Ventricular tumors: surgical options. 61
8076110 1993
8
Epicardial tumor-like angiofibromatous proliferative lesion. An unusual complication of coronary bypass surgery. 61
177825 1976
9
[A giant epicardial tumor]. 61
13083771 1953

Variations for Epicardium Cancer

Expression for Epicardium Cancer

Search GEO for disease gene expression data for Epicardium Cancer.

Pathways for Epicardium Cancer

Pathways related to Epicardium Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.68 UGT1A8 UGT1A1
2
Show member pathways
11.63 UGT1A8 UGT1A1
3 11.36 UGT1A8 UGT1A1
4
Show member pathways
11.27 UGT1A8 UGT1A1
5
Show member pathways
11.17 UGT1A8 UGT1A1
6
Show member pathways
11.08 UGT1A8 UGT1A1
7
Show member pathways
10.93 UGT1A8 UGT1A1
8
Show member pathways
10.72 UGT1A8 UGT1A1
9
Show member pathways
10.15 UGT1A8 UGT1A1

GO Terms for Epicardium Cancer

Biological processes related to Epicardium Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid metabolic process GO:0008202 9.48 UGT1A8 UGT1A1
2 negative regulation of catalytic activity GO:0043086 9.46 UGT1A8 UGT1A1
3 drug metabolic process GO:0017144 9.43 UGT1A8 UGT1A1
4 retinoic acid metabolic process GO:0042573 9.4 UGT1A8 UGT1A1
5 cellular glucuronidation GO:0052695 9.37 UGT1A8 UGT1A1
6 xenobiotic glucuronidation GO:0052697 9.32 UGT1A8 UGT1A1
7 flavonoid glucuronidation GO:0052696 9.26 UGT1A8 UGT1A1
8 negative regulation of fatty acid metabolic process GO:0045922 9.16 UGT1A8 UGT1A1
9 flavone metabolic process GO:0051552 8.96 UGT1A8 UGT1A1
10 negative regulation of steroid metabolic process GO:0045939 8.62 UGT1A8 UGT1A1

Molecular functions related to Epicardium Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.58 UGT1A8 UGT1A1 H2AX
2 protein heterodimerization activity GO:0046982 9.54 UGT1A8 UGT1A1 H2AX
3 enzyme inhibitor activity GO:0004857 9.32 UGT1A8 UGT1A1
4 steroid binding GO:0005496 9.26 UGT1A8 UGT1A1
5 glucuronosyltransferase activity GO:0015020 9.16 UGT1A8 UGT1A1
6 retinoic acid binding GO:0001972 8.96 UGT1A8 UGT1A1
7 UDP-glycosyltransferase activity GO:0008194 8.62 UGT1A8 UGT1A1

Sources for Epicardium Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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