MCID: EPD010
MIFTS: 19

Epidermal Appendage Tumor

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Epidermal Appendage Tumor

MalaCards integrated aliases for Epidermal Appendage Tumor:

Name: Epidermal Appendage Tumor 12 15
Neoplasm of Skin with Adnexal Differentiation 12 74
Neoplasm of the Skin Appendage 12
Skin Appendage Tumour 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2433
NCIt 51 C4463
SNOMED-CT 69 55681005
UMLS 74 C0345988

Summaries for Epidermal Appendage Tumor

MalaCards based summary : Epidermal Appendage Tumor, also known as neoplasm of skin with adnexal differentiation, is related to xeroderma pigmentosum, variant type and chronic salpingitis. An important gene associated with Epidermal Appendage Tumor is CYLD (CYLD Lysine 63 Deubiquitinase), and among its related pathways/superpathways is Deubiquitination. The drug Dermatologic Agents has been mentioned in the context of this disorder. Affiliated tissues include skin and tonsil.

Related Diseases for Epidermal Appendage Tumor

Diseases related to Epidermal Appendage Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 xeroderma pigmentosum, variant type 9.9
2 chronic salpingitis 9.7 CLEC2A TP53
3 spiradenoma 9.7 CYLD TP53
4 tonsil cancer 9.6 CYLD TP53
5 basal cell carcinoma 9.6 CYLD TP53
6 adenoid cystic carcinoma 9.4 CYLD TP53

Graphical network of the top 20 diseases related to Epidermal Appendage Tumor:



Diseases related to Epidermal Appendage Tumor

Symptoms & Phenotypes for Epidermal Appendage Tumor

Drugs & Therapeutics for Epidermal Appendage Tumor

Drugs for Epidermal Appendage Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Dermatologic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 French National Database of Rare Dermatological Cancers Recruiting NCT03210935
2 Extracolonic Findings on Computed Tomography (CT) Colonography Enrolling by invitation NCT01465425

Search NIH Clinical Center for Epidermal Appendage Tumor

Genetic Tests for Epidermal Appendage Tumor

Anatomical Context for Epidermal Appendage Tumor

MalaCards organs/tissues related to Epidermal Appendage Tumor:

42
Skin, Tonsil

Publications for Epidermal Appendage Tumor

Variations for Epidermal Appendage Tumor

Expression for Epidermal Appendage Tumor

Search GEO for disease gene expression data for Epidermal Appendage Tumor.

Pathways for Epidermal Appendage Tumor

Pathways related to Epidermal Appendage Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.34 CYLD TP53

GO Terms for Epidermal Appendage Tumor

Biological processes related to Epidermal Appendage Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein deubiquitination GO:0016579 8.62 CYLD TP53

Molecular functions related to Epidermal Appendage Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein kinase binding GO:0019901 8.62 CYLD TP53

Sources for Epidermal Appendage Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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