Aliases & Classifications for Epidermoid Cysts

MalaCards integrated aliases for Epidermoid Cysts:

Name: Epidermoid Cysts 57
Epidermoid Cyst 54

Characteristics:

OMIM®:

57 (Updated 20-May-2021)
Inheritance:
autosomal dominant


HPO:

31
epidermoid cysts:
Inheritance autosomal dominant inheritance


Classifications:



Summaries for Epidermoid Cysts

MalaCards based summary : Epidermoid Cysts, also known as epidermoid cyst, is related to meningioma, familial and granular cell tumor. An important gene associated with Epidermoid Cysts is S100A1 (S100 Calcium Binding Protein A1), and among its related pathways/superpathways are Keratinization and Ca, cAMP and Lipid Signaling. Affiliated tissues include spleen, testis and brain, and related phenotypes are abnormality of the skin and epidermoid cyst

Wikipedia : 73 An epidermoid cyst or epidermal inclusion cyst is a benign cyst usually found on the skin. The cyst... more...

More information from OMIM: 131600

Related Diseases for Epidermoid Cysts

Diseases related to Epidermoid Cysts via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 394)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 30.3 S100B S100A6 S100A5 S100A1
2 granular cell tumor 29.9 S100B S100A1
3 steatocystoma multiplex 29.8 KRT6A KRT17
4 keratosis, seborrheic 29.3 TCHH KRT17 IVL
5 pilomatrixoma 29.0 TCHH S100B S100A6 S100A3 S100A2 KRT17
6 skin disease 28.6 TCHH S100B KRT6A KRT17 IVL
7 epidermoid brain cyst 11.3
8 dermoid or epidermoid cyst of the central nervous system 11.3
9 follicular atrophoderma, perioral pigmented, with milia and epidermoid cysts 11.1
10 familial adenomatous polyposis 1 11.1
11 pituitary dermoid and epidermoid cysts 11.1
12 teratoma 10.5
13 mature teratoma 10.4
14 cystic teratoma 10.4
15 benign teratoma 10.4
16 conjunctival intraepithelial neoplasm 10.3 S100A2 S100A1
17 trigeminal neuralgia 10.3
18 aseptic meningitis 10.3
19 intracranial meningioma 10.3
20 secretory meningioma 10.3
21 lymphoplasmacyte-rich meningioma 10.3
22 hydrocephalus 10.3
23 malignant iris melanoma 10.3 S100B S100A1
24 lipomatosis, multiple 10.3
25 ptosis 10.3
26 pleomorphic lipoma 10.3
27 molluscum contagiosum 10.3
28 dysphagia 10.3
29 chondromyxoid fibroma 10.3 S100A2 S100A1
30 intraneural perineurioma 10.2 S100B S100A1
31 perineurioma 10.2 S100B S100A1
32 chordoid meningioma 10.2 S100B S100A1
33 ataxia and polyneuropathy, adult-onset 10.2
34 basal cell carcinoma 10.2
35 psoriasis 7 10.2 S100A5 S100A3
36 ossifying fibromyxoid tumor 10.2 S100B S100A1
37 polymorphous low-grade adenocarcinoma 10.2 S100B S100A1
38 paraplegia 10.2
39 head injury 10.2
40 spiradenoma 10.2 S100B S100A1
41 spindle cell rhabdomyosarcoma 10.2 S100B S100A1
42 arachnoid cysts, intracranial 10.2
43 cholesteatoma of middle ear 10.2
44 urinary tract infection 10.2
45 splenomegaly 10.2
46 juvenile xanthogranuloma 10.2 S100B S100A1
47 syringoma 10.2 S100B S100A1
48 adenoma 10.2
49 intracranial hypertension 10.2
50 germ cells tumors 10.2

Graphical network of the top 20 diseases related to Epidermoid Cysts:



Diseases related to Epidermoid Cysts

Symptoms & Phenotypes for Epidermoid Cysts

Human phenotypes related to Epidermoid Cysts:

31
# Description HPO Frequency HPO Source Accession
1 abnormality of the skin 31 HP:0000951
2 epidermoid cyst 31 HP:0200040

Symptoms via clinical synopsis from OMIM®:

57 (Updated 20-May-2021)
Skin:
epidermoid cysts

Clinical features from OMIM®:

131600 (Updated 20-May-2021)

Drugs & Therapeutics for Epidermoid Cysts

Search Clinical Trials , NIH Clinical Center for Epidermoid Cysts

Genetic Tests for Epidermoid Cysts

Anatomical Context for Epidermoid Cysts

MalaCards organs/tissues related to Epidermoid Cysts:

40
Spleen, Testis, Brain, Bone, Skin, Pineal, Breast

Publications for Epidermoid Cysts

Articles related to Epidermoid Cysts:

(show top 50) (show all 2945)
# Title Authors PMID Year
1
Could APC gene screening be useful in children with hepatoblastoma? Early onset of adenocarcinoma in a child with familial adenomatous polyposis and hepatoblastoma. 54 61
20210251 2009
2
Human papillomavirus-associated plantar epidermoid cyst related to epidermoid metaplasia of the eccrine duct epithelium: a combined histological, immunohistochemical, DNA-DNA in situ hybridization and three-dimensional reconstruction analysis. 54 61
15888153 2005
3
Differential expression of S100 calcium-binding proteins in epidermoid cysts, branchial cysts, craniopharyngiomas and cholesteatomas. 54 61
12653951 2003
4
Falsely increased beta-human chorionic gonadotropin with a testicular epidermoid cyst. 54 61
11696768 2001
5
Expression of keratins (K10 and K17) in steatocystoma multiplex, eruptive vellus hair cysts, and epidermoid and trichilemmal cysts. 54 61
9185910 1997
6
Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene. 54 61
7485167 1995
7
Epidermoid cyst of the spleen: a cytokeratin profile with comparison to other squamous epithelia. 61 54
7514079 1994
8
An investigation of cytokeratin expression in skin epithelial cysts and some uncommon types of cystic tumours using chain-specific antibodies. 61 54
1701984 1990
9
Brain lymphoma development related to a long lasting epidermoid cyst. 61
33745844 2021
10
Management and outcome of paediatric testicular tumours - A 20 year experience. 61
33789803 2021
11
Concurrent Thoracic Spinal Intradural Extramedullary Epidermoid and Neurenteric Cyst in a Spinal Dysraphism Child. 61
33784692 2021
12
A Huge Hemorrhagic Epidermoid Cyst of the Perineum with Hypoechoic Semisolid Ultrasonographic Feature Mimicking Scar Endometriosis. 61
33802800 2021
13
Aesthetic Reconstruction After Removal of Huge Epidermal Cyst Involving the Calvarium and Dura on the Scalp. 61
33704987 2021
14
Multicompartmental epidermoid cyst causing chronic parotid gland and masticator space muscles atrophy. 61
33798775 2021
15
Intrasellar epidermoid cyst. A case report. 61
33771502 2021
16
Letter to the Editor Regarding "Split-Pons Syndrome by Epidermoid Cyst: A Case Report and Review of the Literature". 61
33685008 2021
17
Pituitary infundibular epidermoid cyst: a rare cause of hypopituitarism. 61
33762289 2021
18
Infected congenital lumbosacral dermal sinus tract with conus epidermoid abscess: a rare entity. 61
33247382 2021
19
Undifferentiated carcinoma arising from intracranial epidermoid cyst. 61
33559277 2021
20
An unusual neck mass in an adult: epidermoid cyst. 61
33567799 2021
21
Epidermoid cyst of the cecum resected by single-incision laparoscopic colectomy: a case report. 61
33630182 2021
22
Infraoccipital Supratentorial Approach Resection of a Left Mesiotemporal and Atrium Epidermoid Cyst. 61
33242666 2021
23
Verrucous epidermoid cyst on the back containing high risk human papillomaviruses-16 and 59. 61
32790081 2021
24
A rare case of a subungual epidermoid cyst treated by surgical excision maintaining maximal functionality. 61
33521214 2021
25
Spermatogenesis in pre-pubertal boys with Leydig cell neoplasms suggests paracrine stimulation by testosterone. 61
33129671 2021
26
A pilot study of minimal invasion combined PDL/Nd:YAG laser in treating facial epidermoid cyst. 61
33569899 2021
27
Resection of an Isolated Pituitary Stalk Epidermoid Cyst Through a Pretemporal Approach: Case Report and Review of the Literature. 61
32920157 2021
28
Epidermoid Cyst Extending Along Trigeminal Nerve Pathway with Unusual Imaging Findings. 61
33144211 2021
29
Endoscopic resection of sellar and suprasellar epidermoid cyst: report of two cases and review of literature. 61
33517784 2021
30
Cutaneous Keratocyst With D2-40 Immunoreactivity in Basal Cell Nevus Syndrome. 61
33606372 2021
31
Combined Endoscopic Endonasal and Contralateral Transmaxillary Approach for Petrous Cholesteatoma: 2-Dimensional Operative Video. 61
33575736 2021
32
Surgical management of cerebellopontine angle epidermoid cysts: an institutional experience of 10 years. 61
33410366 2021
33
Congenital Spinal Cysts: An Update and Review of the Literature. 61
32822959 2021
34
Posttraumatic Giant Intradiploic Epidermoid Cyst of Orbital Roof. 61
32675762 2021
35
Microwave ablation for the removal of pharyngeal benign lesions: A prospective pilot case series. 61
33485048 2021
36
Epidermoid cyst of the anterior clinoid process: report of a unique finding and literature review of the middle cranial fossa locations. 61
33302123 2021
37
Fully Endoscopic Resection of an Epidermoid Cyst of the Cerebellopontine Angle: Bilateral Resection via a Unilateral Approach. 61
32970119 2021
38
Ultrasound-guided sclerotherapy for recurrent epidermoid cyst: A case report. 61
33200867 2021
39
Conservative parenchymal surgery in testicular tumors. 61
33507639 2021
40
Naturopathic Treatment of an Inflamed Epidermoid Cyst: A Case Report. 61
33488308 2020
41
Intradiploic Epidermoid Cyst Causing Otitis Media with Effusion: Case Report and Review of the Literature. 61
32882457 2020
42
Spontaneous Regression of Radiologically Diagnosed Epidermoid Cyst Originating from the Cerebellopontine Angle. 61
32971281 2020
43
Bilateral Testicular Epidermoid Cysts in a Man with Klinefelter Syndrome: A Case Report. 61
33274173 2020
44
Teledermatology reduces dermatology referrals and improves access to specialists. 61
33437950 2020
45
Pediatric sublingual dermoid and epidermoid cysts: A 20-year institutional review. 61
32795730 2020
46
A great malignancy mimicker: Testicular epidermoid cysts with atypical sonographic and MRI appearance. 61
33102065 2020
47
Effect of simultaneous surgical treatment in scoliosis associated with intraspinal abnormalities: A retrospective study. 61
32989387 2020
48
An epidermoid cyst of the uvula causing dyspnea in an infant: A case report. 61
33181645 2020
49
Epidermoid cyst in an intrapancreatic accessory spleen in the pancreas head: a case report. 61
33218300 2020
50
Primary Epidermoid Cyst of the Clitoris in Adult Female Population: Three Case Reports and Introducing a Safe Surgical Approach. 61
33159314 2020

Variations for Epidermoid Cysts

Expression for Epidermoid Cysts

Search GEO for disease gene expression data for Epidermoid Cysts.

Pathways for Epidermoid Cysts

Pathways related to Epidermoid Cysts according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.71 TCHH KRT6A KRT17 IVL
2 11.03 S100B S100A6 S100A4 S100A1

GO Terms for Epidermoid Cysts

Cellular components related to Epidermoid Cysts according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.32 TCHH S100B S100A6 S100A3 S100A1 KRT6A
2 cornified envelope GO:0001533 8.96 TCHH IVL

Biological processes related to Epidermoid Cysts according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 morphogenesis of an epithelium GO:0002009 9.26 KRT6A KRT17
2 keratinization GO:0031424 9.26 TCHH KRT6A KRT17 IVL
3 intermediate filament organization GO:0045109 9.16 TCHH KRT17
4 cornification GO:0070268 8.92 TCHH KRT6A KRT17 IVL

Molecular functions related to Epidermoid Cysts according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.97 TCHH S100B S100A6 S100A5 S100A4 S100A3
2 calcium ion binding GO:0005509 9.76 TCHH S100B S100A6 S100A5 S100A4 S100A3
3 S100 protein binding GO:0044548 9.43 S100B S100A6 S100A1
4 transition metal ion binding GO:0046914 9.35 TCHH S100A5 S100A4 S100A3 S100A2
5 RAGE receptor binding GO:0050786 9.32 S100B S100A4
6 calcium-dependent protein binding GO:0048306 9.17 S100B S100A6 S100A5 S100A4 S100A3 S100A2

Sources for Epidermoid Cysts

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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