MCID: EPD012
MIFTS: 22

Epididymal Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Epididymal Neoplasm

MalaCards integrated aliases for Epididymal Neoplasm:

Name: Epididymal Neoplasm 12 15
Neoplasm of Epididymis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:512
NCIt 49 C39958
SNOMED-CT 67 126902008
UMLS 71 C0346239

Summaries for Epididymal Neoplasm

MalaCards based summary : Epididymal Neoplasm, also known as neoplasm of epididymis, is related to epididymis cancer and adenomatoid tumor. An important gene associated with Epididymal Neoplasm is MYOD1 (Myogenic Differentiation 1), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and FOXA2 and FOXA3 transcription factor networks. Related phenotype is Decreased sensitivity to paclitaxel.

Related Diseases for Epididymal Neoplasm

Diseases related to Epididymal Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 218)
# Related Disease Score Top Affiliating Genes
1 epididymis cancer 30.4 WT1 PAX2 MME KRT7 CALB2 AFP
2 adenomatoid tumor 29.2 WT1 KRT7 CALB2 AFP
3 pineal region teratoma 10.4 MYOD1 AFP
4 leydig cell tumor 10.4 CALB2 AFP
5 botryoid rhabdomyosarcoma 10.4 MYOD1 AFP
6 adult type testicular granulosa cell tumor 10.3 CALB2 AFP
7 dermoid cyst of ovary 10.3 CALB2 AFP
8 papillary thymic adenocarcinoma 10.3 CALB2 AFP
9 infected hydrocele 10.3 CALB2 AFP
10 hydrocele 10.3 CALB2 AFP
11 granulomatous orchitis 10.3 CD68 AFP
12 intrahepatic bile duct adenoma 10.3 KRT7 AFP
13 rectum neuroendocrine neoplasm 10.3 KRT7 AFP
14 myoblastoma 10.3 CD68 CALB2
15 renal pelvis adenocarcinoma 10.3 KRT7 AFP
16 lymphohistiocytoid mesothelioma 10.3 CD68 CALB2
17 ovarian endodermal sinus tumor 10.3 KRT7 AFP
18 endodermal sinus tumor 10.3 KRT7 AFP
19 cystic lymphangioma 10.3 CALB2 AFP
20 bile duct cystadenocarcinoma 10.3 KRT7 AFP
21 intratubular embryonal carcinoma 10.3 KRT7 AFP
22 ovarian primitive germ cell tumor 10.3 KRT7 AFP
23 colonic lymphangioma 10.3 KRT7 AFP
24 conventional fibrosarcoma 10.3 MYOD1 CD68
25 granular cell tumor 10.3 CD68 CALB2
26 biliary tract benign neoplasm 10.2 KRT7 AFP
27 sarcomatous intrahepatic cholangiocarcinoma 10.2 KRT7 AFP
28 bile duct cysts 10.2 KRT7 AFP
29 thymus clear cell carcinoma 10.2 KRT7 CALB2
30 mediastinal cancer 10.2 KRT7 AFP
31 liver lymphoma 10.2 MME AFP
32 ovarian serous adenofibroma 10.2 KRT7 CALB2
33 rete testis adenoma 10.2 PAX2 CALB2
34 ovarian serous cystadenofibroma 10.2 KRT7 CALB2
35 mucinous stomach adenocarcinoma 10.2 KRT7 CALB2
36 appendix disease 10.2 KRT7 CALB2
37 fallopian tube adenocarcinoma 10.2 MME CALB2
38 sclerosing hepatic carcinoma 10.2 MME AFP
39 appendix cancer 10.2 KRT7 CALB2
40 horseshoe kidney 10.2 KRT7 CALB2
41 hepatoid adenocarcinoma 10.2 KRT7 AFP
42 malignant spiradenoma 10.2 KRT7 CALB2
43 nephrogenic adenoma 10.2 PAX2 KRT7
44 clear cell adenocarcinoma 10.2 PAX2 KRT7
45 heart lymphoma 10.2 MME CD68
46 spermatic cord cancer 10.2 WT1 MYOD1
47 klatskin's tumor 10.2 KRT7 AFP
48 monophasic synovial sarcoma 10.2 KRT7 CALB2
49 t-cell/histiocyte rich large b cell lymphoma 10.2 MME CD68
50 sarcomatoid squamous cell skin carcinoma 10.2 MME CD68

Graphical network of the top 20 diseases related to Epididymal Neoplasm:



Diseases related to Epididymal Neoplasm

Symptoms & Phenotypes for Epididymal Neoplasm

GenomeRNAi Phenotypes related to Epididymal Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased sensitivity to paclitaxel GR00112-A-0 8.62 NF1 WT1

Drugs & Therapeutics for Epididymal Neoplasm

Search Clinical Trials , NIH Clinical Center for Epididymal Neoplasm

Genetic Tests for Epididymal Neoplasm

Anatomical Context for Epididymal Neoplasm

Publications for Epididymal Neoplasm

Articles related to Epididymal Neoplasm:

# Title Authors PMID Year
1
Clear cell papillary cystadenoma of epididymis, a mimic of metastatic renal cell carcinoma. 61
18655434 2008
2
Papillary cystadenoma of the epididymis as a cause of obstructive azoospermia. 61
7855941 1994

Variations for Epididymal Neoplasm

Expression for Epididymal Neoplasm

Search GEO for disease gene expression data for Epididymal Neoplasm.

Pathways for Epididymal Neoplasm

Pathways related to Epididymal Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.26 WT1 PAX2 AFP
2 10.9 NF1 AFP
3 10.67 WT1 PAX2 MME
4 10.36 PAX2 MYOD1

GO Terms for Epididymal Neoplasm

Cellular components related to Epididymal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 presynapse GO:0098793 8.8 NF1 MME CALB2

Biological processes related to Epididymal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.54 PAX2 MME CD68
2 branching involved in ureteric bud morphogenesis GO:0001658 9.4 WT1 PAX2
3 adrenal gland development GO:0030325 9.32 WT1 NF1
4 regulation of long-term synaptic potentiation GO:1900271 9.26 NF1 CALB2
5 mesenchymal to epithelial transition GO:0060231 9.16 WT1 PAX2
6 metanephric mesenchyme development GO:0072075 8.96 WT1 PAX2
7 metanephric epithelium development GO:0072207 8.62 WT1 PAX2

Sources for Epididymal Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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