MCID: EPD012
MIFTS: 22

Epididymal Neoplasm

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Epididymal Neoplasm

MalaCards integrated aliases for Epididymal Neoplasm:

Name: Epididymal Neoplasm 12 15
Neoplasm of Epididymis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:512
NCIt 49 C39958
UMLS 71 C0346239

Summaries for Epididymal Neoplasm

MalaCards based summary : Epididymal Neoplasm, also known as neoplasm of epididymis, is related to epididymis cancer and adenomatoid tumor. An important gene associated with Epididymal Neoplasm is MYOD1 (Myogenic Differentiation 1), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and FOXA2 and FOXA3 transcription factor networks. Related phenotype is Decreased sensitivity to paclitaxel.

Related Diseases for Epididymal Neoplasm

Diseases related to Epididymal Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 219)
# Related Disease Score Top Affiliating Genes
1 epididymis cancer 30.1 WT1 PAX2 MME KRT7 CALB2 AFP
2 adenomatoid tumor 29.2 WT1 KRT7 CALB2 AFP
3 malignant sertoli-leydig cell tumor 10.4 MYOD1 AFP
4 leydig cell tumor 10.4 CALB2 AFP
5 botryoid rhabdomyosarcoma 10.4 MYOD1 AFP
6 malignant leydig cell tumor 10.4 CALB2 AFP
7 malignant sertoli cell tumor 10.4 CALB2 AFP
8 adult type testicular granulosa cell tumor 10.4 CALB2 AFP
9 hematocele of tunica vaginalis testis 10.4 CALB2 AFP
10 lymphangioma 10.3 CALB2 AFP
11 scrotum neoplasm 10.3 CALB2 AFP
12 infected hydrocele 10.3 CALB2 AFP
13 hydrocele 10.3 CALB2 AFP
14 tuberculous epididymitis 10.3 CALB2 AFP
15 intrahepatic bile duct adenoma 10.3 KRT7 AFP
16 renal pelvis adenocarcinoma 10.3 KRT7 AFP
17 myoblastoma 10.3 CD68 CALB2
18 bile duct cystadenocarcinoma 10.3 KRT7 AFP
19 colonic lymphangioma 10.3 KRT7 AFP
20 lymphohistiocytoid mesothelioma 10.3 CD68 CALB2
21 ovarian primitive germ cell tumor 10.3 KRT7 AFP
22 cystic lymphangioma 10.3 CALB2 AFP
23 ovarian endodermal sinus tumor 10.3 KRT7 AFP
24 intratubular embryonal carcinoma 10.3 KRT7 AFP
25 conventional fibrosarcoma 10.3 MYOD1 CD68
26 granular cell tumor 10.3 CD68 CALB2
27 mucinous ovarian cystadenoma 10.3 KRT7 CALB2
28 benign mesenchymoma 10.3 KRT7 AFP
29 sarcomatous intrahepatic cholangiocarcinoma 10.3 KRT7 AFP
30 urachal adenocarcinoma 10.2 NF1 AFP
31 bone leiomyosarcoma 10.2 KRT7 CD68
32 malignant triton tumor 10.2 NF1 MYOD1
33 prostate embryonal rhabdomyosarcoma 10.2 NF1 MYOD1
34 ovarian serous adenofibroma 10.2 KRT7 CALB2
35 mucinous stomach adenocarcinoma 10.2 KRT7 CALB2
36 mediastinal cancer 10.2 KRT7 AFP
37 ovarian serous cystadenofibroma 10.2 KRT7 CALB2
38 rete testis adenoma 10.2 PAX2 CALB2
39 malignant glandular tumor of peripheral nerve sheath 10.2 NF1 CALB2
40 thymus clear cell carcinoma 10.2 KRT7 CALB2
41 benign peritoneal mesothelioma 10.2 KRT7 CALB2
42 gliofibroma 10.2 NF1 MYOD1
43 nephrogenic adenoma 10.2 PAX2 KRT7
44 heart cancer 10.2 KRT7 CALB2
45 clear cell adenocarcinoma 10.2 PAX2 KRT7
46 horseshoe kidney 10.2 KRT7 CALB2
47 klatskin's tumor 10.2 KRT7 AFP
48 spermatic cord cancer 10.2 WT1 MYOD1
49 pulmonary sclerosing hemangioma 10.2 KRT7 CALB2
50 monophasic synovial sarcoma 10.2 KRT7 CALB2

Graphical network of the top 20 diseases related to Epididymal Neoplasm:



Diseases related to Epididymal Neoplasm

Symptoms & Phenotypes for Epididymal Neoplasm

GenomeRNAi Phenotypes related to Epididymal Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased sensitivity to paclitaxel GR00112-A-0 8.62 NF1 WT1

Drugs & Therapeutics for Epididymal Neoplasm

Search Clinical Trials , NIH Clinical Center for Epididymal Neoplasm

Genetic Tests for Epididymal Neoplasm

Anatomical Context for Epididymal Neoplasm

Publications for Epididymal Neoplasm

Articles related to Epididymal Neoplasm:

# Title Authors PMID Year
1
Clear cell papillary cystadenoma of epididymis, a mimic of metastatic renal cell carcinoma. 61
18655434 2008
2
Papillary cystadenoma of the epididymis as a cause of obstructive azoospermia. 61
7855941 1994

Variations for Epididymal Neoplasm

Expression for Epididymal Neoplasm

Search GEO for disease gene expression data for Epididymal Neoplasm.

Pathways for Epididymal Neoplasm

Pathways related to Epididymal Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.26 WT1 PAX2 AFP
2 10.9 NF1 AFP
3 10.67 WT1 PAX2 MME
4 10.36 PAX2 MYOD1

GO Terms for Epididymal Neoplasm

Cellular components related to Epididymal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 presynapse GO:0098793 8.8 NF1 MME CALB2

Biological processes related to Epididymal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.54 PAX2 MME CD68
2 branching involved in ureteric bud morphogenesis GO:0001658 9.4 WT1 PAX2
3 adrenal gland development GO:0030325 9.32 WT1 NF1
4 regulation of long-term synaptic potentiation GO:1900271 9.26 NF1 CALB2
5 mesenchymal to epithelial transition GO:0060231 9.16 WT1 PAX2
6 metanephric mesenchyme development GO:0072075 8.96 WT1 PAX2
7 metanephric epithelium development GO:0072207 8.62 WT1 PAX2

Sources for Epididymal Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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