MCID: EPD005
MIFTS: 32

Epidural Abscess

Categories: Neuronal diseases
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Aliases & Classifications for Epidural Abscess

MalaCards integrated aliases for Epidural Abscess:

Name: Epidural Abscess 11 43 14 16 71 75
Abscess Epidural 11

Classifications:



External Ids:

Disease Ontology 11 DOID:11387
MeSH 43 D020802
SNOMED-CT 68 310671007
UMLS 71 C0270629

Summaries for Epidural Abscess

Disease Ontology: 11 A central nervous system disease that is characterized by a collection of pus (infected material) between the outer covering of the brain and spinal cord and the bones of the skull or spine and is caused by infection in the area between the bones of the skull or spine, and the membranes covering the brain and spinal cord (meninges).

MalaCards based summary: Epidural Abscess, also known as abscess epidural, is related to discitis and subdural empyema. An important gene associated with Epidural Abscess is CRP (C-Reactive Protein), and among its related pathways/superpathways are Complement cascade and IL12 signaling mediated by STAT4. Affiliated tissues include spinal cord, brain and bone.

Wikipedia: 75 An epidural abscess refers to a collection of pus and infectious material located in the epidural space... more...

Related Diseases for Epidural Abscess

Diseases related to Epidural Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 796)
# Related Disease Score Top Affiliating Genes
1 discitis 31.8 MED31 CRP ALB
2 subdural empyema 31.1 F2 CRP
3 meningitis 31.0 IFNG CRP ALB
4 intracranial abscess 30.9 CRP CD4
5 cauda equina syndrome 30.8 F3 F2 CRP
6 pyomyositis 30.8 CRP CD4
7 septic arthritis 30.7 CRP CD4 ALB
8 pleural empyema 30.7 F2 CRP CD4 ALB
9 alcohol use disorder 30.5 F2 CRP CD4 ALB
10 endocarditis 30.5 IFNG F2 CRP ALB
11 actinomycosis 30.5 CRP CD4 ALB
12 lemierre's syndrome 30.4 F3 F2 CRP
13 transverse myelitis 30.4 CRP CD4
14 cat-scratch disease 30.4 CRP CD4
15 infective endocarditis 30.4 F3 F2 CRP ALB
16 otitis media 30.3 IFNG CRP ALB
17 aortic aneurysm, familial abdominal, 1 30.3 F3 CRP ALB
18 acute pyelonephritis 30.3 CRP ALB
19 horner's syndrome 30.3 F3 CRP
20 mastoiditis 30.3 F3 F2 CRP CD4
21 thrombophlebitis 30.3 F3 F2 CRP ALB
22 nocardiosis 30.3 CRP CD4
23 orbital cellulitis 30.3 CRP CD4
24 toxic shock syndrome 30.3 IFNG F3 CRP
25 pyelonephritis 30.3 IFNG CRP ALB
26 blastomycosis 30.2 CRP CD4
27 cholecystitis 30.2 F2 CRP ALB
28 meningoencephalitis 30.2 CRP CD4 ALB
29 gas gangrene 30.2 CRP ALB
30 acquired immunodeficiency syndrome 30.2 IFNG CRP CD4 ALB
31 crohn's disease 30.2 IFNG CRP CD4 ALB
32 gastroenteritis 30.2 IFNG CRP ALB
33 necrotizing fasciitis 30.2 F3 F2 CRP ALB
34 urinary tract infection 30.1 F3 F2 CRP CD4 ALB
35 pericoronitis 30.1 F3 CRP
36 aortic aneurysm 30.1 F3 F2 CRP ALB
37 endophthalmitis 30.1 CRP CD4 ALB
38 pneumonia 30.1 IFNG CRP ALB
39 arachnoiditis 30.1 IFNG CRP CD4
40 appendicitis 30.0 IFNG CRP ALB
41 tenosynovitis 30.0 CRP CD4
42 pyuria 30.0 F2 CRP ALB
43 klebsiella pneumonia 30.0 F3 CRP ALB
44 cellulitis 29.9 F3 F2 CRP CD4 ALB
45 typhoid fever 29.9 IFNG F2 CRP ALB
46 mucormycosis 29.9 IFNG CRP CD4
47 intracranial hypertension 29.9 F3 F2 CRP ALB
48 sagittal sinus thrombosis 29.9 F3 F2 CRP
49 paratyphoid fever 29.9 IFNG CRP
50 cerebritis 29.9 CRP CD4 ALB

Graphical network of the top 20 diseases related to Epidural Abscess:



Diseases related to Epidural Abscess

Symptoms & Phenotypes for Epidural Abscess

Drugs & Therapeutics for Epidural Abscess

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prospective Analysis of Spinal Epidural Abscess Associated Outcomes at the University of Kentucky Recruiting NCT05464251

Search NIH Clinical Center for Epidural Abscess

Cochrane evidence based reviews: epidural abscess

Genetic Tests for Epidural Abscess

Anatomical Context for Epidural Abscess

Organs/tissues related to Epidural Abscess:

MalaCards : Spinal Cord, Brain, Bone, Liver, Prostate, Skin, Lung

Publications for Epidural Abscess

Articles related to Epidural Abscess:

(show top 50) (show all 2234)
# Title Authors PMID Year
1
Spondylitis with epidural abscess and spinal tuberculoma as a major cause of myeloradiculopathy: a case report. 62
36457788 2023
2
Nocardia Farcinica Mastoiditis and Epidural Abscess in an Immunocompetent Patient: A Rare Entity. 62
36453208 2022
3
Holospinal epidural abscess caused by Streptococcus anginosus group: a literature review. 62
36455983 2022
4
Predictors of reoperation after surgery for spinal epidural abscess. 62
35738500 2022
5
Microvascular Reconstruction of the Anterior Skull Base. 62
35984035 2022
6
Pott Luck. 62
36427561 2022
7
Quadriplegia from cervical osteomyelodiscitis with vertebral collapse: A case report. 62
36408081 2022
8
Torcular pseudomass in a 14-month-old child: illustrative case. 62
36377131 2022
9
A 60-Year-Old Man with Gingivitis and Poorly Controlled Diabetes Developing Low Back Pain 1 Week Following Recovery from COVID-19 Diagnosed with Spinal Abscess Due to Streptococcus oralis. 62
36199237 2022
10
Management of Holospinal Epidural Abscess. 62
35863647 2022
11
Oral sequential therapy in the treatment of post-surgical epidural abscess and subdural empyema. 62
35460496 2022
12
Clinical and financial burden of spinal infections in people who inject drugs. 62
34028966 2022
13
An 82-year-old man with a prosthetic aortic valve and multimicrobial bacteremia. 62
36237290 2022
14
A Rare Case of Salmonella Osteomyelitis in Immunocompetent Toddler Without Risk Factors. 62
36426317 2022
15
Nocardia abscessus epidural abscess. 62
35869022 2022
16
The Surgical Management of Holospinal Epidural Abscess: A Case Report and Review on Catheter-Based Irrigation Techniques. 62
36407233 2022
17
Spinal brucellosis causing spondylodiscitis. 62
36268353 2022
18
Extensive Spinal Epidural Abscess Resulting in Complete Paraplegia Treated by Selective Laminectomies and Irrigation. 62
35732468 2022
19
Minimally Invasive Surgical Treatment of Extensive Spinal Epidural Abscess With Unilateral Laminotomy for Bilateral Decompression Using an Ultrasonic Bone Curette: A Technique Note. 62
36162797 2022
20
[Treatment for Pyogenic Spondylodiscitis and Spinal Epidural Abscess]. 62
36128813 2022
21
C-reactive Protein-to-albumin Ratio in Spinal Epidural Abscess: Association with Post-treatment Complications. 62
35984080 2022
22
Epidural abscess formation with an atypical pathogen following epidural steroid injection: A case report. 62
36086689 2022
23
A Case Series of Spinal Infections Following COVID-19: A Delayed Complication. 62
36277530 2022
24
Pyogenic spondylitis caused by Streptococcus dysgalactiae subspecies equisimilis in a patient with nasopharyngeal cancer. 62
35637129 2022
25
Lemierre's syndrome with cranial epidural abscess complication: A case report. 62
36147177 2022
26
Outcomes of Partial Oral Antibiotic Treatment for Complicated S. aureus Bacteremia in People Who Inject Drugs. 62
36052413 2022
27
Pediatric Brain Abscesses, Epidural Empyemas, and Subdural Empyemas Associated with Streptococcus Species - United States, January 2016-August 2022. 62
36107787 2022
28
Development and Validation of a Predictive Model for Failure of Medical Management in Spinal Epidural Abscesses. 62
35584275 2022
29
Cervical Epidural Abscess: A Blind Spot for Postmortem Computed Tomography. 62
34939948 2022
30
Imaging of Spine Infections. 62
36103882 2022
31
Revisiting the Role of Intraoperative Ultrasound in Spine Surgery for Extradural Pathologies: Review and Clinical Usage. 62
35504481 2022
32
Streptococcus gallolyticus-related spinal epidural abscess. 62
35999017 2022
33
[Chronic back pain in axial spondylarthritis : Current diagnostic challenges and treatment possibilities]. 62
36044071 2022
34
Triple Threat: A Case of Erysipelothrix rhusiopathiae Septicemia Complicated by Multi-Valvular Endocarditis, Spinal Osteomyelitis, and Septic Embolic Stroke. 62
36106220 2022
35
Diagnostic delays in infectious diseases. 62
35073468 2022
36
A Rare Case of Aphasia Caused by Delayed Epidural Abscess 6 Years after Cranioplasty. 62
36140442 2022
37
Post-operative clinical course in children undergoing mastoidectomy due to complicated acute mastoiditis. 62
34714371 2022
38
Surgical Management of Spinal Epidural Abscess in Elderly Patients: A Comparative Analysis Between Patients 65-79 Years and ≥80 Years with 3-Year Follow-Up. 62
36041723 2022
39
Imaging characteristics and CT sensitivity for pyogenic spinal infections. 62
35689961 2022
40
Intracranially Extended Sinonasal Undifferentiated Carcinoma: A Case Report and Literature Review. 62
35913898 2022
41
Unexpectedly rapid decrease in the size of a spinal epidural abscess after percutaneous posterior pedicle screw fixation without decompression surgery: a case report. 62
35963854 2022
42
Extensive actinomycosis with intracranial and mediastinal involvement: a therapeutic challenge. 62
35981749 2022
43
Decompression only versus fusion in octogenarians with spinal epidural abscesses: early complications, clinical and radiological outcome with 2-year follow-up. 62
35536406 2022
44
Shewanella algae Causing Pediatric Orbital Abscess With Leptomeningitis. 62
35170566 2022
45
External Review and Validation of a Spinal Epidural Abscess Predictive Score for Clinical Failure. 62
35472643 2022
46
Further considerations regarding spinal epidural abscess in the ED setting. 62
35527096 2022
47
Letter to Editor regarding: "High risk and low prevalence diseases: Spinal epidural abscess". 62
35513933 2022
48
A Case of Methicillin-Sensitive Staphylococcus aureus (MSSA) Prostate Abscess, Osteomyelitis, and Myositis Associated with MSSA Bacteremia in a 60-Year-Old Patient Presenting with Back Pain. 62
35778821 2022
49
Spontaneous Multiloculated Lumbar Abscess in a Middle-Aged Male With Unexplained Progressive Back Pain and Muscle Weakness. 62
36046273 2022
50
Pediatric spinal epidural abscess: recognition and management in the emergency department. 62
35613376 2022

Variations for Epidural Abscess

Expression for Epidural Abscess

Search GEO for disease gene expression data for Epidural Abscess.

Pathways for Epidural Abscess

Pathways related to Epidural Abscess according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.81 IFNG F2 CRP ALB
2 10.75 IFNG CD4
3 10.64 IFNG F2
4 10.37 F3 F2 CD4
5 10.33 IFNG CD4

GO Terms for Epidural Abscess

Sources for Epidural Abscess

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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