MCID: EPD005
MIFTS: 32

Epidural Abscess

Categories: Neuronal diseases

Aliases & Classifications for Epidural Abscess

MalaCards integrated aliases for Epidural Abscess:

Name: Epidural Abscess 12 44 15 73
Abscess Epidural 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11387
MeSH 44 D020802
UMLS 73 C0270629

Summaries for Epidural Abscess

Disease Ontology : 12 A central nervous system disease that is characterized by a collection of pus (infected material) between the outer covering of the brain and spinal cord and the bones of the skull or spine and is caused by infection in the area between the bones of the skull or spine, and the membranes covering the brain and spinal cord (meninges).

MalaCards based summary : Epidural Abscess, also known as abscess epidural, is related to discitis and arachnoiditis. An important gene associated with Epidural Abscess is CRP (C-Reactive Protein). The drugs Cefazolin and Linezolid have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 76 An epidural abscess refers to a collection of pus and infectious material located in the epidural space... more...

Related Diseases for Epidural Abscess

Diseases related to Epidural Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 116)
# Related Disease Score Top Affiliating Genes
1 discitis 31.7 CRP MRI1
2 arachnoiditis 28.0 MNX1 MRI1
3 cervicitis 10.6
4 osteomyelitis 10.5
5 meningitis 10.2
6 arthritis 10.1
7 sinusitis 10.1
8 subdural empyema 10.1
9 pneumonia 10.1
10 endocarditis 10.1
11 brucellosis 10.0
12 pyomyositis 10.0
13 septic arthritis 10.0
14 cauda equina syndrome 10.0
15 quadriplegia 10.0
16 paraplegia 10.0
17 crohn's disease 9.9
18 frontal sinusitis 9.9
19 esophagitis 9.9
20 spondylitis 9.9
21 mastoiditis 9.9
22 gout 9.9
23 prostatitis 9.9
24 cerebritis 9.9
25 back pain 9.9
26 rheumatoid arthritis 9.8
27 cat-scratch disease 9.8
28 actinomycosis 9.8
29 aortic aneurysm, familial abdominal, 1 9.7
30 burns 9.7
31 chronic granulomatous disease 9.7
32 diabetes mellitus 9.7
33 infective endocarditis 9.7
34 lymphoma 9.7
35 thrombosis 9.7
36 sphenoid sinusitis 9.7
37 myelitis 9.7
38 aortic aneurysm 9.7
39 bacterial meningitis 9.7
40 sickle cell disease 9.7
41 aneurysm 9.7
42 headache 9.7
43 bladder cancer 9.6
44 systemic lupus erythematosus 9.6
45 otitis media 9.6
46 parkinson disease, late-onset 9.6
47 pilonidal sinus 9.6
48 pruritic urticarial papules and plaques of pregnancy 9.6
49 aging 9.6
50 sickle cell anemia 9.6

Graphical network of the top 20 diseases related to Epidural Abscess:



Diseases related to Epidural Abscess

Symptoms & Phenotypes for Epidural Abscess

GenomeRNAi Phenotypes related to Epidural Abscess according to GeneCards Suite gene sharing:

26 (show all 15)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.55 SLC2A9
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.55 MNX1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.55 SLC2A9
4 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.55 SLC2A9
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.55 MNX1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.55 SLC2A9
7 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.55 MNX1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.55 MNX1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.55 SLC2A9
10 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.55 MNX1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-46 9.55 MNX1 MRI1 SLC2A9
12 Increased shRNA abundance (Z-score > 2) GR00366-A-5 9.55 SLC2A9
13 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.55 MNX1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-76 9.55 MRI1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.55 SLC2A9

Drugs & Therapeutics for Epidural Abscess

Drugs for Epidural Abscess (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cefazolin Approved Phase 3 25953-19-9 656510 33255
2
Linezolid Approved, Investigational Phase 3 165800-03-3 441401
3
Vancomycin Approved Phase 3 1404-90-6 441141 14969
4 Anti-Bacterial Agents Phase 3
5 Anti-Infective Agents Phase 3
6 Vaccines

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections Terminated NCT00108433 Phase 3 Cefazolin IV;Linezolid IV;Vancomycin (IV)
2 Molecular Microbiology in Osteo-arthritis Infection Completed NCT01193803
3 Maintaining a Prone Position After Use of an Epidural Blood Patch for the Treatment of Post-dural Puncture Headache Terminated NCT02427009 Not Applicable

Search NIH Clinical Center for Epidural Abscess

Cochrane evidence based reviews: epidural abscess

Genetic Tests for Epidural Abscess

Anatomical Context for Epidural Abscess

MalaCards organs/tissues related to Epidural Abscess:

41
Spinal Cord, Brain, Bone, Prostate, Liver, Skin, Testes

Publications for Epidural Abscess

Articles related to Epidural Abscess:

(show top 50) (show all 677)
# Title Authors Year
1
First case of cervical epidural abscess caused by brucellosis in Saudi Arabia: A case report and literature review. ( 29682450 )
2018
2
Aspergillus spinal epidural abscess: case presentation and review of the literature. ( 29531797 )
2018
3
Epidural Abscess During a Spinal Cord Stimulator Trial: A Case Report. ( 29516616 )
2018
4
Postoperative epidural abscess after spinal anaesthesia for a circumcision necessitated by phimosis. ( 29477995 )
2018
5
Epidural abscess caused by Schizophyllum commune: A rare case of rhinogenic cranial complication by a filamentous basidiomycete. ( 29125646 )
2018
6
Independent predictors of spinal epidural abscess recurrence. ( 29649612 )
2018
7
Clinical outcomes of percutaneous suction aspiration and drainage for the treatment of infective spondylodiscitis with paravertebral or epidural abscess. ( 29496623 )
2018
8
Successfully Conservative Management of Delayed Cervical Spondylodiscitis with Epidural Abscess Caused by Esophageal Diverticulitis: A Case Report and Review of Literature. ( 29883818 )
2018
9
Spinal cord compression secondary to epidural abscess: the importance of prompt diagnosis and management. ( 29437718 )
2018
10
Simultaneous occurrence of spinal epidural abscess and disk herniation causing irreversible neurologic deficits: A case report and review of the literature. ( 29721126 )
2018
11
Nonoperative Management of Spinal Epidural Abscess: Development of a Predictive Algorithm for Failure. ( 29613923 )
2018
12
Staphylococcus-Associated Glomerulonephritis Mimicking Henoch-SchAPnlein Purpura and Cryoglobulinemic Vasculitis in a Patient With an Epidural Abscess: A Case Report and Brief Review of the Literature. ( 29900000 )
2018
13
Man-in-the-barrel syndrome: Case report of ventral epidural abscess and review of the literature. ( 29416905 )
2018
14
Post Dengue Fever Epidural abscess with or without Spondylodiscitis-a Case series of 8 patients in a single season in a single Centre: Do the dengue has a predilection for the Neural tissue? ( 29979359 )
2018
15
The Prognostic Accuracy of Suggested Predictors of Failure of Medical Management in Patients With Nontuberculous Spinal Epidural Abscess. ( 29796377 )
2018
16
Lumbar Gout Tophus Mimicking Epidural Abscess with Magnetic Resonance Imaging, Bone, and Gallium Scans. ( 29643682 )
2018
17
Septic arthritis of the temporomandibular joint leading to an epidural abscess. ( 29895543 )
2018
18
A Predictive Model Facilitates Early Recognition of Spinal Epidural Abscess in Adults. ( 29560054 )
2018
19
Tuberculous lumbar spinal epidural abscess in a young adult (case report). ( 29521260 )
2018
20
Development of Predictive Algorithms for Pre-Treatment Motor Deficit and 90-Day Mortality in Spinal Epidural Abscess. ( 29916930 )
2018
21
Lumbar spine epidural abscess and facet joint septic arthritis due to Streptococcus agalactiae: a case report. ( 29534714 )
2018
22
Epidural Abscess: A Propensity Analysis of Surgical Treatment Strategies. ( 29916954 )
2018
23
Spinal Epidural Abscess in an Infant Presenting as Fever and Respiratory Distress. ( 29757891 )
2018
24
Epidural abscess presenting as severe depression with suicidal ideations: Case report. ( 29740504 )
2018
25
The time-sensitive challenge of diagnosing spinal epidural abscess in the emergency department. ( 28779448 )
2017
26
Delayed Brain Edema and Swelling following Craniectomy for Evacuation of an Epidural Abscess that Improved by Cranioplasty: Case Report. ( 28852606 )
2017
27
Cervical epidural analgesia complicated by epidural abscess: A case report and literature review. ( 28984753 )
2017
28
Holospinal epidural abscess combined with multifocal extraspinal abscesses in an elderly patient with rheumatoid arthritis receiving infliximab therapy. ( 29115101 )
2017
29
A spinal epidural abscess due to Streptobacillus moniliformis infection following a rat bite: case report. ( 28430048 )
2017
30
A Pott's Puffy Tumor Associated with Epidural - Cutaneous Fistula and Epidural Abscess: Case Report. ( 28443599 )
2017
31
Epidural Metastasis in Malignant Thymoma Mimicking Epidural Abscess: Case Report and Literature Review. ( 29301178 )
2017
32
Cervical spine epidural abscess: a single center analytical comparison to the literature. ( 28690871 )
2017
33
A Case of Infective Endocarditis and Spinal Epidural Abscess Caused by<i>Streptococcus mitis</i>Bacteremia. ( 29038738 )
2017
34
Spinal Epidural Abscess: A Series of 101 Cases. ( 28797646 )
2017
35
Epidural abscess imitating recurrent pilonidal sinus: a case report. ( 29205143 )
2017
36
Quadriplegia caused by an epidural abscess occurring at the same level of cervical destructive spondyloarthropathy: a case report. ( 28068970 )
2017
37
Edwardsiella tarda Bacteremia with Psoas and Epidural Abscess as a Food-borne Infection: A Case Report and Literature Review. ( 29225255 )
2017
38
Assessment of malpractice claims due to spinal epidural abscess. ( 28498071 )
2017
39
Streptococcus intermedius: an unusual cause of spinal epidural abscess. ( 28744508 )
2017
40
Spinal Epidural Abscess-Conservative or Operative Approach: A Management Dilemma. ( 28672719 )
2017
41
Diskitis, Osteomyelitis, Spinal Epidural Abscess, Meningitis, and Endocarditis Following Sacroiliac Joint Injection for the Treatment of Low-Back Pain in a Patient on Therapy for Hepatitis C Virus. ( 28492440 )
2017
42
A novel case of Raoultella planticola osteomyelitis and epidural abscess. ( 28705846 )
2017
43
CT-guided minimally invasive treatment for an extensive spinal epidural abscess: a case report and literature review. ( 28951964 )
2017
44
Thoracic Spinal Cord Glioblastoma Mimicking Epidural Abscess: Case Report and Literature Review. ( 29104839 )
2017
45
Erratum: Cervical spine epidural abscess: a single center analytical comparison to the literature. ( 29018570 )
2017
46
Spinal epidural abscess: Report on 27 cases. ( 29026676 )
2017
47
A case of panspinal epidural abscess that presented with meningeal irritation. ( 29123892 )
2017
48
Spontaneous spinal epidural abscess in a normoglycemic diabetic patient - Keep it as a differential. ( 28720998 )
2017
49
Successful antibacterial therapy of a spinal epidural abscess in pregnancy: A case report and review of the literature. ( 28017192 )
2017
50
A Protocol-Based Approach to Spinal Epidural Abscess Imaging Improves PerformanceA and Facilitates Early Diagnosis. ( 29102538 )
2017

Variations for Epidural Abscess

Expression for Epidural Abscess

Search GEO for disease gene expression data for Epidural Abscess.

Pathways for Epidural Abscess

GO Terms for Epidural Abscess

Sources for Epidural Abscess

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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