MCID: EPD019
MIFTS: 25

Epidural Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Epidural Neoplasm

MalaCards integrated aliases for Epidural Neoplasm:

Name: Epidural Neoplasm 12 15 17
Epidural Neoplasms 45 74
Extradural Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3618
MeSH 45 D015174
NCIt 51 C3019
UMLS 74 C0014536

Summaries for Epidural Neoplasm

MalaCards based summary : Epidural Neoplasm, also known as epidural neoplasms, is related to spinal cancer and klippel-trenaunay-weber syndrome. An important gene associated with Epidural Neoplasm is PTCHD3 (Patched Domain Containing 3). The drugs Melphalan and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and bone, and related phenotype is Reduced mammosphere formation.

Related Diseases for Epidural Neoplasm

Diseases related to Epidural Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 spinal cancer 11.2
2 klippel-trenaunay-weber syndrome 9.7
3 histiocytoma 9.7
4 fibrous histiocytoma 9.7
5 weber syndrome 9.7
6 angioosteohypertrophic syndrome 9.7
7 invasive mole 9.7

Graphical network of the top 20 diseases related to Epidural Neoplasm:



Diseases related to Epidural Neoplasm

Symptoms & Phenotypes for Epidural Neoplasm

GenomeRNAi Phenotypes related to Epidural Neoplasm according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 8.8 CD27 CD6 SMARCB1

Drugs & Therapeutics for Epidural Neoplasm

Drugs for Epidural Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Melphalan Approved Phase 1 148-82-3 460612 4053
2 Anesthetics Phase 1
3 Alkylating Agents Phase 1
4 Immunologic Factors Phase 1
5 Immunosuppressive Agents Phase 1
6 Antineoplastic Agents, Alkylating Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intra-arterial Chemotherapy for Spinal Metastases Completed NCT01637766 Phase 1 Melphalan (intra-arterial infusion)
2 Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by Surgery Unknown status NCT02527304 Not Applicable
3 Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal Recruiting NCT02790294 Not Applicable
4 The Effects of Labor Stages and Interventions on Hemodynamic Measures During and After Childbirth ( Epidural, Rupture Membranses Cesarean Sections and Preeclampsia) With Noninvasive Sensors. Not yet recruiting NCT03838965 Not Applicable

Search NIH Clinical Center for Epidural Neoplasm

Cochrane evidence based reviews: epidural neoplasms

Genetic Tests for Epidural Neoplasm

Anatomical Context for Epidural Neoplasm

MalaCards organs/tissues related to Epidural Neoplasm:

42
Spinal Cord, Bone

Publications for Epidural Neoplasm

Articles related to Epidural Neoplasm:

# Title Authors Year
1
Plain film clues to the diagnosis of spinal epidural neoplasm and infection. ( 8492898 )
1993
2
Evaluation of back pain caused by epidural neoplasm. ( 24573025 )
1993
3
Identification of epidural neoplasm. Radiography and bone scintigraphy in the symptomatic and asymptomatic spine. ( 2804911 )
1989
4
[Cortical somatosensory evoked potential associated with experimental chronic cord compression by epidural neoplasm in rabbits]. ( 3768192 )
1986
5
Circulatory disturbance of the spinal cord with epidural neoplasm in rats. ( 3926963 )
1985
6
Disturbance of the circulation in the spinal cord with epidural neoplasm. ( 4069060 )
1985
7
Surgical treatment of vertebro-epidural neoplasms of the cervical tract via the anterior approach. ( 6527146 )
1984
8
Edema and circulatory disturbance in the spinal cord compressed by epidural neoplasms in rabbits. ( 7351559 )
1980
9
Experimental spinal cord compression by epidural neoplasm. ( 558545 )
1977
10
Myelopathy caused by metastatic spinal epidural neoplasms. ( 4162986 )
1967

Variations for Epidural Neoplasm

Expression for Epidural Neoplasm

Search GEO for disease gene expression data for Epidural Neoplasm.

Pathways for Epidural Neoplasm

GO Terms for Epidural Neoplasm

Cellular components related to Epidural Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.96 CD27 CD6
2 integral component of plasma membrane GO:0005887 8.8 CD1E CD27 CD6

Biological processes related to Epidural Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 adaptive immune response GO:0002250 8.62 CD1E CD6

Sources for Epidural Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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