MCID: EPG002
MIFTS: 25

Epiglottis Cancer

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Epiglottis Cancer

MalaCards integrated aliases for Epiglottis Cancer:

Name: Epiglottis Cancer 12 15
Malignant Neoplasm of Anterior Surface of Epiglottis 12
Malignant Neoplasm of Anterior Aspect of Epiglottis 12
Malignant Neoplasm of Anterior Epiglottis 12
Malignant Neoplasm of Epiglottis 12
Malignant Tumor of Epiglottis 12
Epiglottic Cancer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8133
ICD9CM 34 146.4
NCIt 49 C35697 C4836
SNOMED-CT 67 93670003 93784003
ICD10 32 C10.1
UMLS 71 C0496765 C0585946 C1112382

Summaries for Epiglottis Cancer

MalaCards based summary : Epiglottis Cancer, also known as malignant neoplasm of anterior surface of epiglottis, is related to glomeruloid hemangioma and lower lip cancer. An important gene associated with Epiglottis Cancer is ABO (ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Hematopoietic cell lineage. Affiliated tissues include bone, thymus and myeloid, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Epiglottis Cancer

Diseases related to Epiglottis Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Related Disease Score Top Affiliating Genes
1 glomeruloid hemangioma 10.3 ENG CD34
2 lower lip cancer 10.3 ENG CD34
3 ischemic bone disease 10.3 ENG ACP5
4 inflammatory liposarcoma 10.2 CYGB CD34
5 lymphangioma 10.2 PDPN CD34
6 rh isoimmunization 10.2 EPO ABO
7 testicular fibroma 10.2 PDPN CD34
8 hobnail hemangioma 10.2 PDPN CD34
9 lymphangiosarcoma 10.2 PDPN CD34
10 blood group incompatibility 10.2 EPO ABO
11 atypical neurofibroma 10.2 PDPN CD34
12 dacryocystocele 10.2 PDPN CAGE1
13 chronic inflammation of lacrimal passage 10.2 PDPN CAGE1
14 malignant giant cell tumor of soft parts 10.2 ENG CD34 ACP5
15 neonatal anemia 10.1 EPO ENG
16 brittle bone disorder 10.1 ENG CD34 ACP5
17 periapical periodontitis 10.1 MMP8 ACP5
18 stress polycythemia 10.1 EPO CYGB
19 late congenital syphilis 10.1 ENG DDX41
20 capillary hemangioma 10.1 PDPN CD34
21 supraglottis neoplasm 10.1 PDPN MMP8
22 acquired polycythemia 10.1 EPO CYGB
23 splenic sequestration 10.1 EPO CYGB
24 lip cancer 10.0 PDPN MMP8
25 cardiovascular cancer 10.0 PDPN CD34
26 microinvasive gastric cancer 10.0 S100A8 PDPN
27 funisitis 10.0 S100A8 MMP8
28 congenital granular cell tumor 10.0 PDPN ENG CD34
29 capillary lymphangioma 10.0 PDPN ENG CD34
30 osteonecrosis 10.0 MMP8 ENG ACP5
31 cardiovascular organ benign neoplasm 10.0 PDPN ENG CD34
32 vascular cancer 10.0 PDPN ENG CD34
33 hemangioma 10.0 PDPN ENG CD34
34 laryngeal benign neoplasm 10.0 PDPN MMP8
35 primary polycythemia 10.0 EPO CD34
36 renal osteodystrophy 9.9 EPO ACP5
37 verrucous carcinoma 9.9
38 mucoepidermoid carcinoma 9.9
39 rosacea 9.9 S100A8 MMP8
40 parathyroid gland disease 9.9 EPO ACP5
41 adult xanthogranuloma 9.9 CD34 CD1D
42 central epithelioid sarcoma 9.9 CD34 CD1D
43 vulvar proximal-type epithelioid sarcoma 9.9 CD34 CD1D
44 supraglottis cancer 9.8 PDPN MMP8 CAGE1
45 epithelioid cell synovial sarcoma 9.8 CD34 CD1D
46 blood platelet disease 9.8 EPO CYGB CD34
47 hemangioblastoma 9.8 PDPN EPO CD34
48 glottis neoplasm 9.8 MMP8 CD1D
49 oral submucous fibrosis 9.8 MMP8 ENG
50 exophthalmos 9.8 CD34 CD1D

Graphical network of the top 20 diseases related to Epiglottis Cancer:



Diseases related to Epiglottis Cancer

Symptoms & Phenotypes for Epiglottis Cancer

GenomeRNAi Phenotypes related to Epiglottis Cancer according to GeneCards Suite gene sharing:

26 (show all 28)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.7 MMP8
2 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.7 ABO
3 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.7 NONO
4 Increased shRNA abundance (Z-score > 2) GR00366-A-138 9.7 NONO
5 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.7 NONO
6 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.7 ABO
7 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.7 NONO
8 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.7 ABO MMP8
9 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.7 NONO
10 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.7 ABO
11 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.7 MMP8
12 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.7 ABO
13 Increased shRNA abundance (Z-score > 2) GR00366-A-208 9.7 MMP8
14 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.7 NONO
15 Increased shRNA abundance (Z-score > 2) GR00366-A-23 9.7 ABO
16 Increased shRNA abundance (Z-score > 2) GR00366-A-41 9.7 MMP8
17 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.7 NONO
18 Increased shRNA abundance (Z-score > 2) GR00366-A-5 9.7 MMP8
19 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.7 MMP8
20 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.7 ABO MMP8 NONO
21 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.7 MMP8
22 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.65 MMP8
23 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.65 MMP8
24 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.65 DDX41
25 Decreased shRNA abundance (Z-score < -2) GR00366-A-184 9.65 MMP8
26 Decreased shRNA abundance (Z-score < -2) GR00366-A-20 9.65 ABO DDX41 MMP8
27 Decreased shRNA abundance (Z-score < -2) GR00366-A-209 9.65 MMP8
28 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.65 ABO DDX41

Drugs & Therapeutics for Epiglottis Cancer

Search Clinical Trials , NIH Clinical Center for Epiglottis Cancer

Genetic Tests for Epiglottis Cancer

Anatomical Context for Epiglottis Cancer

MalaCards organs/tissues related to Epiglottis Cancer:

40
Bone, Thymus, Myeloid

Publications for Epiglottis Cancer

Articles related to Epiglottis Cancer:

# Title Authors PMID Year
1
[ABO blood groups in the patients with laryngeal cancer]. 61
10974887 2000
2
[Horizontal subglottic laryngectomy in treating cancers of the laryngeal vestibule and vallecula. Apropos of 65 cases]. 61
9207975 1996
3
ABO blood groups system in laryngeal cancer patients and after survival of 3 and 5 years. 61
1308059 1992
4
[Curability of laryngeal cancer in relation to the starting point]. 61
1808584 1991
5
[EPIGLOTTIS STRUCTURES IN EPIGLOTTIS CANCER (HISTOPATHOLOGIC STUDY AND CLINICAL CONSIDERATIONS)]. 61
14234508 1964

Variations for Epiglottis Cancer

Expression for Epiglottis Cancer

Search GEO for disease gene expression data for Epiglottis Cancer.

Pathways for Epiglottis Cancer

Pathways related to Epiglottis Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.2 EPO ENG CD34
2 10.79 EPO CD34 CD1D

GO Terms for Epiglottis Cancer

Biological processes related to Epiglottis Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell proliferation GO:0008283 9.33 EPO DDX41 CD34
2 response to lipopolysaccharide GO:0032496 9.13 S100A8 EPO ACP5
3 negative regulation of nitric oxide biosynthetic process GO:0045019 8.62 CD34 ACP5

Sources for Epiglottis Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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