Epiglottis Cancer disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Epiglottis Cancer

MalaCards integrated aliases for Epiglottis Cancer:

Name: Epiglottis Cancer ¹² ¹⁵

Malignant Tumor of Epiglottis ¹²

Epiglottic Cancer ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Neoplasms

Malignant neoplasms of lip, oral cavity and pharynx

Malignant neoplasm of oropharynx

Malignant neoplasm: Anterior surface of epiglottis

External Ids:

Disease Ontology ¹² DOID:8133

ICD9CM ³⁴ 146.4

NCIt ⁵⁰ C35697 C4836

SNOMED-CT ⁶⁷ 187849008 93670003

ICD10 ³² C10.1

UMLS ⁷¹ C0496765 C0585946 C1112382

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Summaries for Epiglottis Cancer

MalaCards based summary : Epiglottis Cancer, also known as malignant tumor of epiglottis, is related to tibial nerve palsy and ischemic bone disease. An important gene associated with Epiglottis Cancer is ACP5 (Acid Phosphatase 5, Tartrate Resistant), and among its related pathways/superpathways are Hematopoietic cell lineage and Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers.

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Related Diseases for Epiglottis Cancer

Diseases related to Epiglottis Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 54)

#	Related Disease	Score	Top Affiliating Genes
1	tibial nerve palsy	10.1	ENG CD34
2	ischemic bone disease	10.1	ENG ACP5
3	glomeruloid hemangioma	10.1	ENG CD34
4	lower lip cancer	10.1	ENG CD34
5	neonatal anemia	10.0	EPO ENG
6	osteonecrosis	10.0	ENG ACP5
7	bone benign neoplasm	10.0	CD34 ACP5
8	mobitz type ii atrioventricular block	10.0	ENG CD34
9	parathyroid gland disease	10.0	EPO ACP5
10	myelophthisic anemia	10.0	EPO CD34
11	folic acid deficiency anemia	10.0	EPO CYGB
12	inflammatory liposarcoma	10.0	CYGB CD34
13	germ cell and embryonal cancer	10.0	ENG CD34
14	secondary hyperparathyroidism	10.0	EPO ACP5
15	acquired polycythemia	9.9	EPO CYGB
16	splenic sequestration	9.9	EPO CYGB
17	hyperparathyroidism	9.9	EPO ACP5
18	blood protein disease	9.9	EPO CD34
19	nodular tenosynovitis	9.9	PDPN ACP5
20	verrucous carcinoma	9.9
21	mucoepidermoid carcinoma	9.9
22	supraglottis neoplasm	9.9	PDPN CAGE1
23	malignant giant cell tumor of soft parts	9.9	ENG CD34 ACP5
24	ureteral obstruction	9.9	EPO ENG
25	lymphangioma	9.9	PDPN CD34
26	colonic lymphangioma	9.9	PDPN CD34
27	hobnail hemangioma	9.9	PDPN CD34
28	testicular fibroma	9.9	PDPN CD34
29	subglottis neoplasm	9.9	PDPN CAGE1
30	brittle bone disorder	9.9	ENG CD34 ACP5
31	lymphangiosarcoma	9.9	PDPN CD34
32	angiosarcoma	9.9	PDPN CD34
33	atypical neurofibroma	9.8	PDPN CD34
34	neurofibroma	9.8	PDPN CD34
35	laryngeal benign neoplasm	9.8	PDPN CAGE1
36	benign peritoneal mesothelioma	9.8	PDPN CD34
37	cystic lymphangioma	9.8	PDPN CD34
38	myoma	9.8	EPO CD34
39	capillary hemangioma	9.8	PDPN CD34
40	benign mesothelioma	9.8	PDPN CD34
41	bone marrow cancer	9.7	EPO CD34
42	hemoglobinopathy	9.7	EPO CYGB CD34
43	deficiency anemia	9.7	EPO CYGB CD34
44	blood platelet disease	9.7	EPO CYGB CD34
45	blood coagulation disease	9.7	EPO CYGB CD34
46	vascular disease	9.7	EPO ENG CD34
47	capillary lymphangioma	9.7	PDPN ENG CD34
48	congenital granular cell tumor	9.7	PDPN ENG CD34
49	vascular cancer	9.7	PDPN ENG CD34
50	cardiovascular organ benign neoplasm	9.7	PDPN ENG CD34

Graphical network of the top 20 diseases related to Epiglottis Cancer:

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Symptoms & Phenotypes for Epiglottis Cancer

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Drugs & Therapeutics for Epiglottis Cancer

Search Clinical Trials , NIH Clinical Center for Epiglottis Cancer

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Genetic Tests for Epiglottis Cancer

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Anatomical Context for Epiglottis Cancer

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Publications for Epiglottis Cancer

Articles related to Epiglottis Cancer:

#	Title	Authors	PMID	Year
1	[ABO blood groups in the patients with laryngeal cancer]. ⁶¹	Nowinska E...Kocierz S	10974887	2000
2	[Horizontal subglottic laryngectomy in treating cancers of the laryngeal vestibule and vallecula. Apropos of 65 cases]. ⁶¹	Godey B...Bourdiniere HJ	9207975	1996
3	ABO blood groups system in laryngeal cancer patients and after survival of 3 and 5 years. ⁶¹	Konieczna A...Turowski G	1308059	1992
4	[Curability of laryngeal cancer in relation to the starting point]. ⁶¹	Osmolski A...Kukulewska-Machnicka J	1808584	1991
5	[EPIGLOTTIS STRUCTURES IN EPIGLOTTIS CANCER (HISTOPATHOLOGIC STUDY AND CLINICAL CONSIDERATIONS)]. ⁶¹	LEONARDELLI GB...CIS C	14234508	1964
6	Epiglottis cancer. ⁶¹	REVESZ G	18889281	1948

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Genes for Epiglottis Cancer

Genes related to Epiglottis Cancer (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ACP5	Acid Phosphatase 5, Tartrate Resistant	Protein Coding	5.55	DISEASES inferred ¹⁵
2	ENG	Endoglin	Protein Coding	5.22	DISEASES inferred ¹⁵
3	CAGE1	Cancer Antigen 1	Protein Coding	4.77	DISEASES inferred ¹⁵
4	CD34	CD34 Molecule	Protein Coding	4.44	DISEASES inferred ¹⁵
5	CYGB	Cytoglobin	Protein Coding	4.41	DISEASES inferred ¹⁵
6	PDPN	Podoplanin	Protein Coding	4.02	DISEASES inferred ¹⁵
7	EPO	Erythropoietin	Protein Coding	3.55	DISEASES inferred ¹⁵

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Variations for Epiglottis Cancer

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Expression for Epiglottis Cancer

Search GEO for disease gene expression data for Epiglottis Cancer.

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Pathways for Epiglottis Cancer

Pathways related to Epiglottis Cancer according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Hematopoietic cell lineage ³⁶	11.32	EPO CD34
2	Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.23	ENG CD34
3	Angiogenesis (CST) ⁴	11.11	PDPN ENG
4	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	10.86	EPO ENG CD34
5	HIF-1-alpha transcription factor network ¹	10.77	EPO ENG

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GO Terms for Epiglottis Cancer

Biological processes related to Epiglottis Cancer according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of neuron death	GO:1901215	9.26	EPO CD34
2	cell motility	GO:0048870	9.16	ENG CD34
3	response to hypoxia	GO:0001666	9.13	EPO ENG CYGB
4	response to hyperoxia	GO:0055093	8.62	PDPN EPO

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Sources for Epiglottis Cancer

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Mar-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia