Epiglottis Cancer disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Epiglottis Cancer

MalaCards integrated aliases for Epiglottis Cancer:

Name: Epiglottis Cancer ¹² ¹⁵

Malignant Neoplasm of Anterior Surface of Epiglottis ¹²

Malignant Neoplasm of Anterior Aspect of Epiglottis ¹²

Malignant Neoplasm of Anterior Epiglottis ¹²

Malignant Neoplasm of Epiglottis ¹²

Malignant Tumor of Epiglottis ¹²

Epiglottic Cancer ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Neoplasms

Malignant neoplasms of lip, oral cavity and pharynx

Malignant neoplasm of oropharynx

Malignant neoplasm: Anterior surface of epiglottis

External Ids:

Disease Ontology ¹² DOID:8133

ICD9CM ³⁴ 146.4

NCIt ⁴⁹ C35697 C4836

SNOMED-CT ⁶⁷ 93670003 93784003

ICD10 ³² C10.1

UMLS ⁷¹ C0496765 C0585946 C1112382

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Summaries for Epiglottis Cancer

MalaCards based summary : Epiglottis Cancer, also known as malignant neoplasm of anterior surface of epiglottis, is related to glomeruloid hemangioma and lower lip cancer. An important gene associated with Epiglottis Cancer is ABO (ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Hematopoietic cell lineage. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

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Related Diseases for Epiglottis Cancer

Diseases related to Epiglottis Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)

#	Related Disease	Score	Top Affiliating Genes
1	glomeruloid hemangioma	10.3	ENG CD34
2	lower lip cancer	10.3	ENG CD34
3	ischemic bone disease	10.3	ENG ACP5
4	inflammatory liposarcoma	10.2	CYGB CD34
5	lymphangioma	10.2	PDPN CD34
6	rh isoimmunization	10.2	EPO ABO
7	testicular fibroma	10.2	PDPN CD34
8	hobnail hemangioma	10.2	PDPN CD34
9	lymphangiosarcoma	10.2	PDPN CD34
10	blood group incompatibility	10.2	EPO ABO
11	atypical neurofibroma	10.2	PDPN CD34
12	dacryocystocele	10.2	PDPN CAGE1
13	chronic inflammation of lacrimal passage	10.2	PDPN CAGE1
14	malignant giant cell tumor of soft parts	10.2	ENG CD34 ACP5
15	neonatal anemia	10.1	EPO ENG
16	brittle bone disorder	10.1	ENG CD34 ACP5
17	periapical periodontitis	10.1	MMP8 ACP5
18	stress polycythemia	10.1	EPO CYGB
19	late congenital syphilis	10.1	ENG DDX41
20	capillary hemangioma	10.1	PDPN CD34
21	supraglottis neoplasm	10.1	PDPN MMP8
22	acquired polycythemia	10.1	EPO CYGB
23	splenic sequestration	10.1	EPO CYGB
24	lip cancer	10.0	PDPN MMP8
25	cardiovascular cancer	10.0	PDPN CD34
26	microinvasive gastric cancer	10.0	S100A8 PDPN
27	funisitis	10.0	S100A8 MMP8
28	congenital granular cell tumor	10.0	PDPN ENG CD34
29	capillary lymphangioma	10.0	PDPN ENG CD34
30	osteonecrosis	10.0	MMP8 ENG ACP5
31	cardiovascular organ benign neoplasm	10.0	PDPN ENG CD34
32	vascular cancer	10.0	PDPN ENG CD34
33	hemangioma	10.0	PDPN ENG CD34
34	laryngeal benign neoplasm	10.0	PDPN MMP8
35	primary polycythemia	10.0	EPO CD34
36	renal osteodystrophy	9.9	EPO ACP5
37	verrucous carcinoma	9.9
38	mucoepidermoid carcinoma	9.9
39	rosacea	9.9	S100A8 MMP8
40	parathyroid gland disease	9.9	EPO ACP5
41	adult xanthogranuloma	9.9	CD34 CD1D
42	central epithelioid sarcoma	9.9	CD34 CD1D
43	vulvar proximal-type epithelioid sarcoma	9.9	CD34 CD1D
44	supraglottis cancer	9.8	PDPN MMP8 CAGE1
45	epithelioid cell synovial sarcoma	9.8	CD34 CD1D
46	blood platelet disease	9.8	EPO CYGB CD34
47	hemangioblastoma	9.8	PDPN EPO CD34
48	glottis neoplasm	9.8	MMP8 CD1D
49	oral submucous fibrosis	9.8	MMP8 ENG
50	exophthalmos	9.8	CD34 CD1D

Graphical network of the top 20 diseases related to Epiglottis Cancer:

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Symptoms & Phenotypes for Epiglottis Cancer

GenomeRNAi Phenotypes related to Epiglottis Cancer according to GeneCards Suite gene sharing:

²⁶ (show all 28)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-100	9.7	MMP8
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-114	9.7	ABO
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-120	9.7	NONO
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-138	9.7	NONO
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-149	9.7	NONO
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-152	9.7	ABO
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-163	9.7	NONO
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-176	9.7	ABO MMP8
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-177	9.7	NONO
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-186	9.7	ABO
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-199	9.7	MMP8
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-2	9.7	ABO
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-208	9.7	MMP8
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-21	9.7	NONO
15	Increased shRNA abundance (Z-score > 2)	GR00366-A-23	9.7	ABO
16	Increased shRNA abundance (Z-score > 2)	GR00366-A-41	9.7	MMP8
17	Increased shRNA abundance (Z-score > 2)	GR00366-A-47	9.7	NONO
18	Increased shRNA abundance (Z-score > 2)	GR00366-A-5	9.7	MMP8
19	Increased shRNA abundance (Z-score > 2)	GR00366-A-52	9.7	MMP8
20	Increased shRNA abundance (Z-score > 2)	GR00366-A-74	9.7	ABO MMP8 NONO
21	Increased shRNA abundance (Z-score > 2)	GR00366-A-99	9.7	MMP8
22	Decreased shRNA abundance (Z-score < -2)	GR00366-A-139	9.65	MMP8
23	Decreased shRNA abundance (Z-score < -2)	GR00366-A-145	9.65	MMP8
24	Decreased shRNA abundance (Z-score < -2)	GR00366-A-154	9.65	DDX41
25	Decreased shRNA abundance (Z-score < -2)	GR00366-A-184	9.65	MMP8
26	Decreased shRNA abundance (Z-score < -2)	GR00366-A-20	9.65	ABO DDX41 MMP8
27	Decreased shRNA abundance (Z-score < -2)	GR00366-A-209	9.65	MMP8
28	Decreased shRNA abundance (Z-score < -2)	GR00366-A-213	9.65	ABO DDX41

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Drugs & Therapeutics for Epiglottis Cancer

Search Clinical Trials , NIH Clinical Center for Epiglottis Cancer

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Genetic Tests for Epiglottis Cancer

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Anatomical Context for Epiglottis Cancer

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Publications for Epiglottis Cancer

Articles related to Epiglottis Cancer:

#	Title	Authors	PMID	Year
1	[ABO blood groups in the patients with laryngeal cancer]. ⁶¹	Nowinska E...Kocierz S	10974887	2000
2	[Horizontal subglottic laryngectomy in treating cancers of the laryngeal vestibule and vallecula. Apropos of 65 cases]. ⁶¹	Godey B...Bourdiniere HJ	9207975	1996
3	ABO blood groups system in laryngeal cancer patients and after survival of 3 and 5 years. ⁶¹	Konieczna A...Turowski G	1308059	1992
4	[Curability of laryngeal cancer in relation to the starting point]. ⁶¹	Osmolski A...Kukulewska-Machnicka J	1808584	1991
5	[EPIGLOTTIS STRUCTURES IN EPIGLOTTIS CANCER (HISTOPATHOLOGIC STUDY AND CLINICAL CONSIDERATIONS)]. ⁶¹	LEONARDELLI GB...CIS C	14234508	1964

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Genes for Epiglottis Cancer

Genes related to Epiglottis Cancer (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ABO	ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase	Protein Coding	5.8	DISEASES inferred ¹⁵
2	ACP5	Acid Phosphatase 5, Tartrate Resistant	Protein Coding	5.42	DISEASES inferred ¹⁵
3	ENG	Endoglin	Protein Coding	5.08	DISEASES inferred ¹⁵
4	NONO	Non-POU Domain Containing Octamer Binding	Protein Coding	4.59	DISEASES inferred ¹⁵
5	CAGE1	Cancer Antigen 1	Protein Coding	4.46	DISEASES inferred ¹⁵
6	CD34	CD34 Molecule	Protein Coding	4.3	DISEASES inferred ¹⁵
7	S100A8	S100 Calcium Binding Protein A8	Protein Coding	4.13	DISEASES inferred ¹⁵
8	CYGB	Cytoglobin	Protein Coding	4.08	DISEASES inferred ¹⁵
9	PDPN	Podoplanin	Protein Coding	3.9	DISEASES inferred ¹⁵
10	MMP8	Matrix Metallopeptidase 8	Protein Coding	3.85	DISEASES inferred ¹⁵
11	DDX41	DEAD-Box Helicase 41	Protein Coding	3.56	DISEASES inferred ¹⁵
12	CD1D	CD1d Molecule	Protein Coding	3.55	DISEASES inferred ¹⁵
13	EPO	Erythropoietin	Protein Coding	3.39	DISEASES inferred ¹⁵

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Variations for Epiglottis Cancer

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Expression for Epiglottis Cancer

Search GEO for disease gene expression data for Epiglottis Cancer.

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Pathways for Epiglottis Cancer

Pathways related to Epiglottis Cancer according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.2	EPO ENG CD34
2	Hematopoietic cell lineage ³⁶	10.79	EPO CD34 CD1D

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GO Terms for Epiglottis Cancer

Biological processes related to Epiglottis Cancer according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cell proliferation	GO:0008283	9.33	EPO DDX41 CD34
2	response to lipopolysaccharide	GO:0032496	9.13	S100A8 EPO ACP5
3	negative regulation of nitric oxide biosynthetic process	GO:0045019	8.62	CD34 ACP5

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Sources for Epiglottis Cancer

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

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¹⁰ dbSNP

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¹⁶ DrugBank

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¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

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³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

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⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

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⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

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⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

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⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia