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SCFE
MCID: EPP010
MIFTS: 26

Epiphysiolysis of the Hip (SCFE)

Categories: Bone diseases, Rare diseases
Tissues Related diseases Publications Drugs
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Aliases & Classifications for Epiphysiolysis of the Hip

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MalaCards integrated aliases for Epiphysiolysis of the Hip:

Name: Epiphysiolysis of the Hip 59
Slipped Upper Femoral Epiphysis 59 33
Slipped Capital Femoral Epiphysis 59
Epiphysiolysis of the Upper Femur 59
Slipped Capital Femoral Epiphyses 72
Femoral Head Epiphysiolysis 59
Scfe 59
Sufe 59

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Bone diseases
See all MalaCards categories (disease lists)
ICD10: 33 34
Orphanet: 59  
Rare systemic and rhumatological diseases
Rare bone diseases


External Ids:

ICD10 33 M93.0
ICD10 via Orphanet 34 M93.9
Orphanet 59 ORPHA399329
UMLS 72 C0149887
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Summaries for Epiphysiolysis of the Hip

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MalaCards based summary : Epiphysiolysis of the Hip, also known as slipped upper femoral epiphysis, is related to legg-calve-perthes disease and epiphyseal chondrodysplasia, miura type. The drugs Gentamicins and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include bone, kidney and thyroid.

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Related Diseases for Epiphysiolysis of the Hip

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Diseases related to Epiphysiolysis of the Hip via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 legg-calve-perthes disease 12.1
2 epiphyseal chondrodysplasia, miura type 11.8
3 avascular necrosis 11.4
4 slipped femoral capital epiphyses 11.2
5 osteonecrosis 11.1
6 hypothyroidism 11.0
7 osteoarthritis 10.9
8 hypogonadism 10.8
9 hypogonadotropism 10.8
10 hyperparathyroidism 10.8
11 pituitary hormone deficiency, combined, 2 10.8
12 body mass index quantitative trait locus 1 10.8
13 renal osteodystrophy 10.7
14 primary hyperparathyroidism 10.7
15 growth hormone deficiency 10.7
16 synovitis 10.7
17 hypopituitarism 10.7
18 overgrowth syndrome 10.7
19 gonadal dysgenesis 10.6
20 turner syndrome 10.6
21 down syndrome 10.6
22 chondromalacia 10.6
23 craniopharyngioma 10.6
24 adenoma 10.6
25 parathyroid adenoma 10.6
26 gigantism 10.6
27 prader-willi syndrome 10.5
28 scoliosis 10.5
29 bone disease 10.5
30 rickets 10.5
31 osteopetrosis 10.5
32 blount's disease 10.5
33 ankylosis 10.5
34 pik3ca-related overgrowth syndrome 10.5
35 body mass index quantitative trait locus 11 10.4
36 body mass index quantitative trait locus 9 10.4
37 body mass index quantitative trait locus 8 10.4
38 body mass index quantitative trait locus 4 10.4
39 body mass index quantitative trait locus 10 10.4
40 body mass index quantitative trait locus 7 10.4
41 chromosome 16p13.3 deletion syndrome, proximal 10.4
42 body mass index quantitative trait locus 12 10.4
43 body mass index quantitative trait locus 14 10.4
44 body mass index quantitative trait locus 18 10.4
45 body mass index quantitative trait locus 19 10.4
46 body mass index quantitative trait locus 20 10.4
47 hypogonadotropic hypogonadism 10.4
48 osteomyelitis 10.4
49 osteomalacia 10.4
50 cerebral palsy 10.4

Graphical network of the top 20 diseases related to Epiphysiolysis of the Hip:



Diseases related to Epiphysiolysis of the Hip
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Symptoms & Phenotypes for Epiphysiolysis of the Hip

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Drugs & Therapeutics for Epiphysiolysis of the Hip

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Drugs for Epiphysiolysis of the Hip (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Gentamicins Phase 4
2 Anti-Bacterial Agents Phase 4
3 Anti-Infective Agents Phase 4
4 Sodium Chloride Symporter Inhibitors Phase 4
5 diuretics Phase 4
6 Natriuretic Agents Phase 4
7 Hormones Phase 4
8 Hormone Antagonists Phase 4
9 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
10
Pamidronate Approved 40391-99-9 4674
11 Diphosphonates
12 Bone Density Conservation Agents

Interventional clinical trials:

(show all 20)
# Name Status NCT ID Phase Drugs
1 A Prospective, Randomised, Uncontrolled, Single-Centre, Post-Market Surveillance Study To Evaluate The Performance Of SmartSet® HV and SmartSet® GHV Bone Cements In Primary Cemented Total Hip Arthroplasty(THA) Completed NCT00872066 Phase 4
2 A Prospective, Randomised, Controlled, Single Centre, Blinded Study of the Wear Characteristics of Two Polyethylene Bearing Surfaces, Enduron vs. Marathon Completed NCT00208442 Phase 4
3 Prospective, Uncontrolled, Multi-Centre, Post-Marketing Surveillance Study to Evaluate the Long-Term Performance of Summit Tapered Hip in Cementless Total Hip Arthroplasty Terminated NCT00208390 Phase 4
4 Prospective, Uncontrolled, Two-centre, RSA, Post-market Surveillance Study to Evaluate the Stability of the C-Stem™ AMT Femoral Component in Primary Total Hip Arthroplasty. Terminated NCT00872573 Phase 4
5 Uncontrolled Prospective Multi-Centre Post Marketing Surveillance Study to Monitor the Long Term Survivorship of Pinnacle™ Acetabular Cup Prosthesis With a Ceramic-on-ceramic Bearing in Subjects With Aetiologies Requiring a Primary Total Hip Replacement Terminated NCT00872222 Phase 4
6 Prospective Multi-Centre, Uncontrolled, Post Marketing Surveillance Study to Monitor the Long-Term Performance of the DePuy ASR Hip System in Subjects With Suitable Indications for a Primary Resurfacing Hip Arthroplasty Terminated NCT00208377 Phase 4
7 Uncontrolled Prospective Multi-Centre Post Marketing Surveillance Study to Monitor the Long Term Survivorship of Pinnacle Acetabular Cup Prosthesis With a Metal on Metal Bearing in Subjects With Aetiologies Requiring a Primary Total Hip Replacement Terminated NCT00208364 Phase 4
8 Randomised, Controlled, Prospective, Multi-Centre, Post Market Surveillance Study Comparing a Ceramic-on-Metal Bearing and a Metal-on-Metal Bearing in Subjects Requiring Primary Total Hip Arthroplasty for Non-Inflammatory Degenerative Joint Disease Terminated NCT00873444 Phase 4
9 Prospective Single-centre, Uncontrolled, Post Marketing Surveillance Study to Monitor the Long-term Performance of the DePuy ASR™ Hip in Subjects With Suitable Indications for a Primary Resurfacing Hip Arthroplasty Terminated NCT00872794 Phase 4
10 Prospective, International Multi-centre, Uncontrolled, Post Marketing Surveillance Study to Monitor the Long-term Performance of a Large Metal-on-Metal (MoM) Bearing Comprising a DePuy ASR™ Cup in Conjunction With Either a DePuy ASR™ Hip Resurfacing Femoral Component or a DePuy ASR™ XL Head in Subjects With Indications Suitable for Either a Primary Resurfacing Arthroplasty or Primary Total Hip Arthroplasty Terminated NCT00872547 Phase 4
11 A Multicenter Study of the Effect of Recombinant Human Growth Hormone on Leptin and Cytokines in Relation to Body Composition in Pediatric Patients With Growth Failure Due to Chronic Kidney Disease (CKD) Terminated NCT00194961 Phase 4 Recombinant Human Growth Hormone
12 Uncontrolled Prospective Multi-Centre Post Marketing Surveillance Study to Monitor the Long Term Survivorship of Pinnacle Acetabular Cup System With a Metal on Enduron Polyethylene Bearing in Subjects With Aetiologies Requiring a Primary Total Hip Replacement Withdrawn NCT00208429 Phase 4
13 A Multi-centre, Randomised, Parallel Group, Controlled Study to Compare the Performance of the Future Hip Against Three Currently Used Implants in Total Hip Replacement Terminated NCT00208468 Phase 3
14 Clinical and Radiographic Evaluation to Compare a Polished and Non-polished Collared Stem and a Polished and Non Polished Collarless Stem in Primary Total Hip Replacement Terminated NCT00208351 Phase 3
15 Skeletal Age Assessment From the Olecranon For Slipped Capital Femoral Epiphysis Unknown status NCT01220882
16 The Effect of Somatic Dysfunction of the Pelvis, Sacrum and Lower Lumbar Spine on Weight Bearing Completed NCT01097109
17 Study on the Diagnostic Qualities of the Positron Emission Tomography Coupled to the Scanner (PET / CT) in the Assessment of Response to Non-Hodgkin's Lymphoma Therapy in Children and Adolescents Completed NCT02488369
18 Slipped Capital Femoral Epiphysis; Changes in Gait, Balance and Muscle Activity Patterns in Patients Treated With Single Screw in Situ Fixation Investigated Using Computer Assisted Rehabilitation ENvironment (CAREN) Recruiting NCT03326531
19 Safe Surgical Dislocation in Slipped Capital Femoral Epiphysis Not yet recruiting NCT03229590
20 The Use of Bisphosphonates in the Treatment of Avascular Necrosis of the Femoral Head Terminated NCT02007915 Pamidronate Disodium

Search NIH Clinical Center for Epiphysiolysis of the Hip

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Genetic Tests for Epiphysiolysis of the Hip

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Anatomical Context for Epiphysiolysis of the Hip

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MalaCards organs/tissues related to Epiphysiolysis of the Hip:

41
Bone, Kidney, Thyroid, Pituitary
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Publications for Epiphysiolysis of the Hip

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Articles related to Epiphysiolysis of the Hip:

(show top 50) (show all 168)
# Title Authors PMID Year
1
Alshryda S et al. Evidence based treatment for unstable slipped upper femoral epiphysis: Systematic review and exploratory patient level analysis. The Surgeon. 2018; 16: 46-54. 38
30514665 2019
2
Authors' response to the letter re: Evidence based treatment for unstable slipped upper femoral epiphysis: Systematic review and exploratory patient level analysis. 38
29954672 2019
3
Slipped Upper Femoral Epiphysis: Are We Missing the Point? 38
30533329 2018
4
Recognition and nursing management of children with non-traumatic limp. 38
29521078 2018
5
Evidence based treatment for unstable slipped upper femoral epiphysis: Systematic review and exploratory patient level analysis. 38
27255978 2018
6
Femoral Head Stress Fracture in Children: A Case Report. 38
29600201 2017
7
Vitamin D Deficiency in Slipped Upper Femoral Epiphysis: Time to Physeal Fusion. 38
25785591 2016
8
Outcomes following subcapital osteotomy for severe slipped upper femoral epiphysis. 38
26637690 2015
9
The seasonality of slipped upper femoral epiphysis--meta-analysis: a possible association with vitamin D. 38
26044532 2015
10
Tibia vara and slipped upper femoral epiphysis: is there an association? 38
25192368 2015
11
The child with joint pain in primary care. 38
26096092 2014
12
Severe slipped upper femoral epiphysis; fish osteotomy versus pinning-in-situ: an eleven year perspective. 38
24090679 2014
13
A modified Imhäuser osteotomy: an assessment of the addition of an open femoral neck osteoplasty. 38
25086130 2014
14
The frequency of sequelae of slipped upper femoral epiphysis in cam-type femoroacetabular impingement. 38
24891570 2014
15
Establishing the entry point for in situ pinning of slipped upper femoral epiphysis. 38
24780033 2014
16
Hashimoto's hypothyroidism presenting with SUFE (slipped upper femoral epiphysis). 38
24639334 2014
17
The evolution and concepts of joint-preserving surgery of the hip. 38
24395304 2014
18
Hardware complications related to the surgical fixation of slipped capital femoral epiphyses. 38
25272215 2014
19
Reslip of a previously fixed slipped upper femoral epiphysis with an associated vitamin d deficiency. 38
24716062 2014
20
Slipped upper femoral epiphysis: Outcome after in situ fixation and capital realignment technique. 38
24600074 2014
21
Persisting growth after prophylactic single-screw epiphysiodesis in upper femoral epiphysis. 38
24096449 2013
22
Slipped upper femoral epiphysis: Outcome after in situ fixation and capital realignment technique. 38
23798757 2013
23
Femoroacetabular impingement after slipped upper femoral epiphysis: the radiological diagnosis and clinical outcome at long-term follow-up. 38
23109627 2012
24
Total hip arthroplasty in teenagers: an alternative to hip arthrodesis. 38
23233183 2012
25
Use of Gamma locking nail(®) in tri-planar osteotomy in bilateral severe slipped upper femoral epiphysis: a case study and literature review. 38
20809384 2012
26
Early results of total hip arthroplasty in patients with slipped upper femoral epiphysis compared with patients with osteoarthritis. 38
22333869 2012
27
Management of the contralateral hip in patients with unilateral slipped upper femoral epiphysis: to fix or not to fix--consequences of two strategies. 38
22529076 2012
28
Freehand technique for in situ pinning of slipped upper femoral epiphysis. 38
22497017 2012
29
Vitamin D deficiency: a paediatric orthopaedic perspective. 38
22189396 2012
30
[Slipped upper femoral epiphysis (SUFE)]. 38
21842453 2011
31
A case of slipped upper femoral epiphysis in a nonambulant patient with cerebral palsy. 38
21537202 2011
32
Single screw fixation in stable and unstable slipped upper femoral epiphysis. 38
21386718 2011
33
Continued growth of the hip after fixation of slipped capital femoral epiphysis using a single cannulated screw with a proximal threading. 38
22468150 2011
34
Radiographic assessment of bone remodelling in slipped upper femoral epiphyses using Klein's line and the α angle of femoral-acetabular impingement: a retrospective review. 38
21307709 2011
35
Slipped upper femoral epiphysis: a case of missed diagnosis. 38
22490452 2011
36
Prognostic significance of stability in slipped upper femoral epiphysis: a systematic review and meta-analysis. 38
20605166 2010
37
Slipped upper femoral epiphysis. 38
20645436 2010
38
Symphysis pubis width and unaffected hip joint width in patients with slipped upper femoral epiphysis: widening compared with normal values. 38
19705114 2010
39
Slipped upper femoral epiphysis in children--delays to diagnosis. 38
20369118 2010
40
Slipped upper femoral epiphysis in a 19-year-old male. 38
19838133 2010
41
Slipped upper femoral epiphysis--a case of a 'dodgem hip'. 38
19833009 2009
42
Severe hip infection after a prophylactic contralateral fixation in slipped upper femoral epiphysis: a case report. 38
19512946 2009
43
Accuracy of computer-assisted navigation for femoral head resurfacing decreases in hips with abnormal anatomy. 38
19421830 2009
44
Hip arthroplasty up to the age of 30 and considerations in relation to subsequent revision. 38
19891048 2009
45
Slipped upper femoral epiphysis in Hashimoto's thyroiditis in a 29-year-old man. 38
19407305 2009
46
Managing children with acute non-traumatic limp: the utility of clinical findings, laboratory inflammatory markers and X-rays. 38
19422411 2009
47
Femoroacetabular impingement: current status of diagnosis and treatment: Marius Nygaard Smith-Petersen, 1886-1953. 38
19132453 2009
48
The classic: Treatment of malum coxae senilis, old slipped upper femoral epiphysis, intrapelvic protrusion of the acetabulum, and coxa plana by means of acetabuloplasty. 1936. 38
19089521 2009
49
Hip radiography for the investigation of nontraumatic, short duration hip pain presenting to a children's emergency department. 38
19194345 2009
50
Slipped Upper Femoral Epiphysis (SUFE): to do or not to do in sufe. 38
19306243 2009
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Variations for Epiphysiolysis of the Hip

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Expression for Epiphysiolysis of the Hip

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Search GEO for disease gene expression data for Epiphysiolysis of the Hip.
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Pathways for Epiphysiolysis of the Hip

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GO Terms for Epiphysiolysis of the Hip

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Sources for Epiphysiolysis of the Hip

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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