MCID: EPT029
MIFTS: 22

Epithelioid Inflammatory Myofibroblastic Sarcoma

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Epithelioid Inflammatory Myofibroblastic Sarcoma

MalaCards integrated aliases for Epithelioid Inflammatory Myofibroblastic Sarcoma:

Name: Epithelioid Inflammatory Myofibroblastic Sarcoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0080372

Summaries for Epithelioid Inflammatory Myofibroblastic Sarcoma

Disease Ontology : 12 An inflammatory myofibroblastic tumor composed of epithelioid or round cells with a characteristic perinuclear or nuclear membrane staining pattern with ALK immunohistochemistry, frequently dispersed in myxoid stroma with prominent neutrophils or lymphocytes, and often absence of plasma cells.

MalaCards based summary : Epithelioid Inflammatory Myofibroblastic Sarcoma is related to inflammatory myofibroblastic tumor and sarcoma. An important gene associated with Epithelioid Inflammatory Myofibroblastic Sarcoma is ALK (ALK Receptor Tyrosine Kinase), and among its related pathways/superpathways are Cardiac muscle contraction and Striated Muscle Contraction. Affiliated tissues include small intestine, colon and ovary.

Related Diseases for Epithelioid Inflammatory Myofibroblastic Sarcoma

Graphical network of the top 20 diseases related to Epithelioid Inflammatory Myofibroblastic Sarcoma:



Diseases related to Epithelioid Inflammatory Myofibroblastic Sarcoma

Symptoms & Phenotypes for Epithelioid Inflammatory Myofibroblastic Sarcoma

Drugs & Therapeutics for Epithelioid Inflammatory Myofibroblastic Sarcoma

Search Clinical Trials , NIH Clinical Center for Epithelioid Inflammatory Myofibroblastic Sarcoma

Genetic Tests for Epithelioid Inflammatory Myofibroblastic Sarcoma

Anatomical Context for Epithelioid Inflammatory Myofibroblastic Sarcoma

MalaCards organs/tissues related to Epithelioid Inflammatory Myofibroblastic Sarcoma:

40
Small Intestine, Colon, Ovary, Kidney, Pituitary

Publications for Epithelioid Inflammatory Myofibroblastic Sarcoma

Articles related to Epithelioid Inflammatory Myofibroblastic Sarcoma:

(show all 33)
# Title Authors PMID Year
1
[Clinicopathological features of inflammatory myofibroblastic tumor]. 61
33677881 2021
2
Crizotinib-associated Renal Cyst Formation in a Pediatric Patient With ALK+ Epithelioid Inflammatory Myofibroblastic Sarcoma. 61
32882306 2021
3
CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma. 61
32684628 2020
4
Sigmoid epithelioid inflammatory myofibroblastic sarcoma with high white blood cell count: A case report. 61
32245659 2020
5
Diagnostic utility of pan-Trk immunohistochemistry for inflammatory myofibroblastic tumours. 61
31578734 2020
6
[Epithelioid inflammatory myofibroblastic sarcoma of the small intestine: report of two cases]. 61
31594049 2019
7
Posttransplant epithelioid inflammatory myofibroblastic sarcoma: A case report. 61
30971562 2019
8
ALK-G1269A mutation in epithelioid inflammatory myofibroblastic sarcoma after progression on crizotinib: A case report. 61
30675302 2019
9
Epithelioid Inflammatory Myofibroblastic Sarcoma. 61
29623737 2019
10
Epithelioid inflammatory myofibroblastic sarcoma of stomach: diagnostic pitfalls and clinical characteristics. 61
31933992 2019
11
A case report on epithelioid inflammatory myofibroblastic sarcoma in the abdominal cavity. 61
31933785 2019
12
Epithelioid Inflammatory Myofibroblastic Sarcoma of the Ovary With RANB2-ALK Fusion: Report of a Case. 61
28787324 2018
13
Clinicopathological analysis of epithelioid inflammatory myofibroblastic sarcoma. 61
29805657 2018
14
Crizotinib in ALK+ inflammatory myofibroblastic tumors-Current experience and future perspectives. 61
29286567 2018
15
'ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma'. 61
28543105 2017
16
Identification of EML4-ALK as an alternative fusion gene in epithelioid inflammatory myofibroblastic sarcoma. 61
28535796 2017
17
[Epithelioid inflammatory myofibroblastic sarcoma of small bowel mesentery: report of a case]. 61
28297765 2017
18
ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma. 61
27874193 2017
19
[Epithelioid inflammatory myofibroblastic sarcoma: a clinicopathologic analysis of 3 cases]. 61
27430694 2016
20
Epithelioid inflammatory myofibroblastic sarcoma: a clinicopathological, immunohistochemical and molecular cytogenetic analysis of five additional cases and review of the literature. 61
27460384 2016
21
Incomplete Intestinal Obstruction Caused by a Rare Epithelioid Inflammatory Myofibroblastic Sarcoma of the Colon: A Case Report. 61
26705227 2015
22
Epithelioid inflammatory myofibroblastic sarcoma: a case report. 61
26623133 2015
23
The New Kids on the Block: Recently Characterized Soft Tissue Tumors. 61
26297066 2015
24
Cytopathologic features of epithelioid inflammatory myofibroblastic sarcoma with correlation of histopathology, immunohistochemistry, and molecular cytogenetic analysis. 61
26139079 2015
25
Pulmonary epithelioid inflammatory myofibroblastic sarcoma with multiple bone metastases: case report and review of literature. 61
26178751 2015
26
Epithelioid inflammatory myofibroblastic sarcoma in abdominal cavity: a case report and review of literature. 61
26097614 2015
27
Epithelioid inflammatory myofibroblastic sarcoma with recurrence after extensive resection: significant clinicopathologic characteristics of a rare aggressive soft tissue neoplasm. 61
26191301 2015
28
Epithelioid inflammatory myofibroblastic sarcoma treated with ALK inhibitor: a case report and review of literature. 61
26823889 2015
29
A case report of epithelioid inflammatory myofibroblastic sarcoma with RANBP2-ALK fusion gene treated with the ALK inhibitor, crizotinib. 61
25028698 2014
30
Epithelioid inflammatory myofibroblastic sarcoma arising in the pleural cavity. 61
23345154 2014
31
ALK inhibition for the treatment of refractory epithelioid inflammatory myofibroblastic sarcoma. 61
25274227 2014
32
Epithelioid inflammatory myofibroblastic sarcoma responsive to surgery and an ALK inhibitor in a patient with panhypopituitarism. 61
25274232 2014
33
Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK. 61
21164297 2011

Variations for Epithelioid Inflammatory Myofibroblastic Sarcoma

Expression for Epithelioid Inflammatory Myofibroblastic Sarcoma

Search GEO for disease gene expression data for Epithelioid Inflammatory Myofibroblastic Sarcoma.

Pathways for Epithelioid Inflammatory Myofibroblastic Sarcoma

Pathways related to Epithelioid Inflammatory Myofibroblastic Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.1 TPM4 TPM3
2 10.81 TPM4 TPM3
3 10.18 TPM4 TPM3

GO Terms for Epithelioid Inflammatory Myofibroblastic Sarcoma

Cellular components related to Epithelioid Inflammatory Myofibroblastic Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin filament GO:0005884 9.16 TPM4 TPM3
2 stress fiber GO:0001725 8.96 TPM4 TPM3
3 muscle thin filament tropomyosin GO:0005862 8.62 TPM4 TPM3

Biological processes related to Epithelioid Inflammatory Myofibroblastic Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein transport GO:0015031 9.43 SEC31A RRBP1 RANBP2
2 actin filament organization GO:0007015 9.32 TPM4 TPM3
3 muscle contraction GO:0006936 9.16 TPM4 TPM3
4 osteoblast differentiation GO:0001649 8.96 TPM4 RRBP1
5 muscle filament sliding GO:0030049 8.62 TPM4 TPM3

Sources for Epithelioid Inflammatory Myofibroblastic Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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