MCID: EPT029
MIFTS: 24

Epithelioid Inflammatory Myofibroblastic Sarcoma

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Epithelioid Inflammatory Myofibroblastic Sarcoma

MalaCards integrated aliases for Epithelioid Inflammatory Myofibroblastic Sarcoma:

Name: Epithelioid Inflammatory Myofibroblastic Sarcoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0080372

Summaries for Epithelioid Inflammatory Myofibroblastic Sarcoma

Disease Ontology : 12 An inflammatory myofibroblastic tumor composed of epithelioid or round cells with a characteristic perinuclear or nuclear membrane staining pattern with ALK immunohistochemistry, frequently dispersed in myxoid stroma with prominent neutrophils or lymphocytes, and often absence of plasma cells.

MalaCards based summary : Epithelioid Inflammatory Myofibroblastic Sarcoma is related to inflammatory myofibroblastic tumor and sarcoma. An important gene associated with Epithelioid Inflammatory Myofibroblastic Sarcoma is ALK (ALK Receptor Tyrosine Kinase), and among its related pathways/superpathways are Cytoskeletal Signaling and Pathways in cancer. Affiliated tissues include neutrophil, lung and colon.

Related Diseases for Epithelioid Inflammatory Myofibroblastic Sarcoma

Diseases related to Epithelioid Inflammatory Myofibroblastic Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
# Related Disease Score Top Affiliating Genes
1 inflammatory myofibroblastic tumor 29.9 ALK EML4 RANBP2 TPM3
2 sarcoma 10.8
3 spindle cell sarcoma 10.5
4 pediatric fibrosarcoma 10.2 TFG TPM3
5 hereditary wilms' tumor 10.2 ALK WT1
6 lung papillary adenocarcinoma 10.2 ALK EML4
7 lung adenoid cystic carcinoma 10.2 ALK EML4
8 chronic eosinophilic leukemia 10.2 TPM3 WT1
9 hodgkin's lymphoma, lymphocytic depletion 10.1 ALK TNFRSF8
10 colon lymphoma 10.1 ALK TNFRSF8
11 pituitary hormone deficiency, combined, 2 10.1
12 intestinal obstruction 10.1
13 adult fibrosarcoma 10.1 MYOG WT1
14 spindle cell liposarcoma 10.1 MYOG WT1
15 adult lymphoma 10.0 ALK TNFRSF8
16 intravascular fasciitis 10.0 ALK CALD1
17 pediatric lymphoma 10.0 ALK TNFRSF8
18 lung lymphoma 10.0 ALK TNFRSF8
19 childhood kidney cell carcinoma 10.0 ALK EML4 TPM3
20 in situ pulmonary adenocarcinoma 10.0 ALK EML4
21 rhabdomyosarcoma 2 10.0 ALK MYOG WT1
22 ecthyma 10.0 ALK TNFRSF8
23 anaplastic large cell lymphoma 9.9 ALK TFG TNFRSF8
24 peritoneal benign neoplasm 9.9 CALD1 WT1
25 diffuse peritoneal leiomyomatosis 9.9 CALD1 WT1
26 reticulosarcoma 9.9 ALK TNFRSF8
27 lung combined type small cell carcinoma 9.9 CALD1 MYOG
28 inflammatory leiomyosarcoma 9.9 CALD1 MYOG
29 conventional leiomyosarcoma 9.9 CALD1 MYOG
30 lymphatic system cancer 9.9 ALK TNFRSF8
31 chondrosarcoma, extraskeletal myxoid 9.8 TFG WT1
32 conventional fibrosarcoma 9.8 CALD1 TNFRSF8
33 pseudosarcomatous fibromatosis 9.8 CALD1 MYOG
34 hematologic cancer 9.8 ALK TNFRSF8 WT1
35 nephrogenic adenofibroma 9.7 CALD1 MYOG WT1
36 malignant mesenchymoma 9.7 CALD1 MYOG WT1
37 muscle cancer 9.7 CALD1 MYOG WT1
38 mesenchymal cell neoplasm 9.7 ALK CALD1 RANBP2 TPM3
39 muscular disease 9.6 CALD1 MYOG TPM3
40 ewing sarcoma 9.5 ALK MYOG TNFRSF8 WT1

Graphical network of the top 20 diseases related to Epithelioid Inflammatory Myofibroblastic Sarcoma:



Diseases related to Epithelioid Inflammatory Myofibroblastic Sarcoma

Symptoms & Phenotypes for Epithelioid Inflammatory Myofibroblastic Sarcoma

Drugs & Therapeutics for Epithelioid Inflammatory Myofibroblastic Sarcoma

Search Clinical Trials , NIH Clinical Center for Epithelioid Inflammatory Myofibroblastic Sarcoma

Genetic Tests for Epithelioid Inflammatory Myofibroblastic Sarcoma

Anatomical Context for Epithelioid Inflammatory Myofibroblastic Sarcoma

MalaCards organs/tissues related to Epithelioid Inflammatory Myofibroblastic Sarcoma:

42
Neutrophil, Lung, Colon, Bone, Ovary, Kidney, Pituitary

Publications for Epithelioid Inflammatory Myofibroblastic Sarcoma

Articles related to Epithelioid Inflammatory Myofibroblastic Sarcoma:

(show all 21)
# Title Authors Year
1
Epithelioid Inflammatory Myofibroblastic Sarcoma. ( 29623737 )
2019
2
ALK-G1269A mutation in epithelioid inflammatory myofibroblastic sarcoma after progression on crizotinib: A case report. ( 30675302 )
2019
3
Posttransplant epithelioid inflammatory myofibroblastic sarcoma: A case report. ( 30971562 )
2019
4
Epithelioid Inflammatory Myofibroblastic Sarcoma of the Ovary With RANB2-ALK Fusion: Report of a Case. ( 28787324 )
2018
5
Clinicopathological analysis of epithelioid inflammatory myofibroblastic sarcoma. ( 29805657 )
2018
6
ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma. ( 27874193 )
2017
7
Identification of EML4-ALK as an alternative fusion gene in epithelioid inflammatory myofibroblastic sarcoma. ( 28535796 )
2017
8
'ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma'. ( 28543105 )
2017
9
Epithelioid inflammatory myofibroblastic sarcoma: a clinicopathological, immunohistochemical and molecular cytogenetic analysis of five additional cases and review of the literature. ( 27460384 )
2016
10
Epithelioid inflammatory myofibroblastic sarcoma in abdominal cavity: a case report and review of literature. ( 26097614 )
2015
11
Cytopathologic features of epithelioid inflammatory myofibroblastic sarcoma with correlation of histopathology, immunohistochemistry, and molecular cytogenetic analysis. ( 26139079 )
2015
12
Pulmonary epithelioid inflammatory myofibroblastic sarcoma with multiple bone metastases: case report and review of literature. ( 26178751 )
2015
13
Epithelioid inflammatory myofibroblastic sarcoma with recurrence after extensive resection: significant clinicopathologic characteristics of a rare aggressive soft tissue neoplasm. ( 26191301 )
2015
14
Epithelioid inflammatory myofibroblastic sarcoma: a case report. ( 26623133 )
2015
15
Incomplete Intestinal Obstruction Caused by a Rare Epithelioid Inflammatory Myofibroblastic Sarcoma of the Colon: A Case Report. ( 26705227 )
2015
16
Epithelioid inflammatory myofibroblastic sarcoma treated with ALK inhibitor: a case report and review of literature. ( 26823889 )
2015
17
Epithelioid inflammatory myofibroblastic sarcoma arising in the pleural cavity. ( 23345154 )
2014
18
A case report of epithelioid inflammatory myofibroblastic sarcoma with RANBP2-ALK fusion gene treated with the ALK inhibitor, crizotinib. ( 25028698 )
2014
19
ALK inhibition for the treatment of refractory epithelioid inflammatory myofibroblastic sarcoma. ( 25274227 )
2014
20
Epithelioid inflammatory myofibroblastic sarcoma responsive to surgery and an ALK inhibitor in a patient with panhypopituitarism. ( 25274232 )
2014
21
Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK. ( 21164297 )
2011

Variations for Epithelioid Inflammatory Myofibroblastic Sarcoma

Expression for Epithelioid Inflammatory Myofibroblastic Sarcoma

Search GEO for disease gene expression data for Epithelioid Inflammatory Myofibroblastic Sarcoma.

Pathways for Epithelioid Inflammatory Myofibroblastic Sarcoma

Pathways related to Epithelioid Inflammatory Myofibroblastic Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.82 CALD1 DCTN1 EML4
2 11.65 ALK EML4 TFG TPM3
3 10.51 CALD1 TPM3

GO Terms for Epithelioid Inflammatory Myofibroblastic Sarcoma

Cellular components related to Epithelioid Inflammatory Myofibroblastic Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.23 CALD1 DCTN1 EML4 RANBP2 TFG TNFRSF8

Sources for Epithelioid Inflammatory Myofibroblastic Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
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43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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