MCID: EPT011
MIFTS: 30

Epithelioid Leiomyosarcoma

Categories: Cancer diseases, Muscle diseases

Aliases & Classifications for Epithelioid Leiomyosarcoma

MalaCards integrated aliases for Epithelioid Leiomyosarcoma:

Name: Epithelioid Leiomyosarcoma 12 15
Leiomyosarcoma, Epithelioid 73
Leiomyosarcoma Epithelioid 55

Classifications:



External Ids:

Disease Ontology 12 DOID:5264
MeSH 44 D007890
NCIt 50 C3700
SNOMED-CT 68 42392001
UMLS 73 C0205815

Summaries for Epithelioid Leiomyosarcoma

MalaCards based summary : Epithelioid Leiomyosarcoma, also known as leiomyosarcoma, epithelioid, is related to leiomyosarcoma and uterine corpus epithelioid leiomyosarcoma. An important gene associated with Epithelioid Leiomyosarcoma is DES (Desmin), and among its related pathways/superpathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include uterus, cervix and skin.

Related Diseases for Epithelioid Leiomyosarcoma

Diseases related to Epithelioid Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 122)
# Related Disease Score Top Affiliating Genes
1 leiomyosarcoma 29.3 ACTC1 DES ENO2 VIM
2 uterine corpus epithelioid leiomyosarcoma 12.1
3 infantile digital fibromatosis 10.3 DES VIM
4 lymphangiomatosis 10.3 DES VIM
5 breast rhabdomyosarcoma 10.3 DES ENO2
6 malignant ectomesenchymoma 10.3 DES ENO2
7 ectomesenchymoma 10.3 DES ENO2
8 biphasic synovial sarcoma 10.3 DES VIM
9 syringoma 10.3 DES VIM
10 juvenile xanthogranuloma 10.3 DES VIM
11 mesenchymal chondrosarcoma 10.3 DES VIM
12 bednar tumor 10.2 ENO2 VIM
13 papillary tumor of the pineal region 10.2 ENO2 VIM
14 astroblastoma 10.2 ENO2 VIM
15 melanotic neuroectodermal tumor 10.2 ENO2 VIM
16 medullomyoblastoma 10.2 DES ENO2
17 chondroid chordoma 10.2 ENO2 VIM
18 cerebral primitive neuroectodermal tumor 10.2 ENO2 VIM
19 liver angiosarcoma 10.1 ENO2 VIM
20 muscle cancer 10.1 DES ENO2
21 pericardial mesothelioma 10.1 ENO2 VIM
22 clear cell ependymoma 10.1 ENO2 VIM
23 optic nerve glioma 10.1 ENO2 VIM
24 rhabdomyosarcoma 2 10.1 DES ENO2
25 gastric squamous cell carcinoma 10.1 ENO2 SERPINA3
26 sarcoma, synovial 10.1 DES VIM
27 odontogenic myxoma 10.1 SERPINA3 VIM
28 ependymoma 10.0 ENO2 VIM
29 secretory meningioma 10.0 SERPINA3 VIM
30 retinal hemangioblastoma 10.0 ENO2 SERPINA3
31 chordoma 10.0 DES VIM
32 ovarian fibrothecoma 10.0 ACTC1 DES
33 fibroblastic rheumatism 10.0 ACTC1 DES
34 cutaneous leiomyosarcoma 10.0 ACTC1 DES
35 botryoid rhabdomyosarcoma 10.0 ACTC1 DES
36 liposarcoma 10.0 DES VIM
37 paraganglioma 9.9
38 chondroma 9.9
39 nonsyndromic paraganglioma 9.9
40 pulmonary vein stenosis 9.9 ACTC1 DES
41 cystic nephroma 9.9 ACTC1 DES
42 connective tissue cancer 9.9 ENO2 SERPINA3
43 ischemic fasciitis 9.9 ACTC1 DES
44 lymphangiectasis 9.9 ACTC1 VIM
45 dedifferentiated liposarcoma 9.9 ACTC1 DES
46 non-langerhans-cell histiocytosis 9.9 ACTC1 DES
47 glomangiomyoma 9.9 ACTC1 VIM
48 adenofibroma 9.9 ACTC1 VIM
49 angiocentric glioma 9.8 ACTC1 VIM
50 dendritic cell tumor 9.8 ACTC1 VIM

Graphical network of the top 20 diseases related to Epithelioid Leiomyosarcoma:



Diseases related to Epithelioid Leiomyosarcoma

Symptoms & Phenotypes for Epithelioid Leiomyosarcoma

Drugs & Therapeutics for Epithelioid Leiomyosarcoma

Search Clinical Trials , NIH Clinical Center for Epithelioid Leiomyosarcoma

Genetic Tests for Epithelioid Leiomyosarcoma

Anatomical Context for Epithelioid Leiomyosarcoma

MalaCards organs/tissues related to Epithelioid Leiomyosarcoma:

41
Uterus, Cervix, Skin, Liver, Smooth Muscle, Lymph Node, Ovary

Publications for Epithelioid Leiomyosarcoma

Articles related to Epithelioid Leiomyosarcoma:

(show top 50) (show all 70)
# Title Authors Year
1
Uterine epithelioid leiomyosarcoma with c-kit expression and YWHAE gene rearrangement: a case report of a diagnostic pitfall of uterine sarcoma. ( 28288693 )
2017
2
Cardiac epithelioid leiomyosarcoma as both intracardiac and pericardial mass with massive pericardial effusion: a rare presentation. ( 23916929 )
2013
3
Epithelioid Leiomyosarcoma Arising in the Subcutis-A New Case Report of a Rare Variant. ( 23739249 )
2013
4
Epithelioid leiomyosarcoma of uterus. ( 22602833 )
2012
5
A case of tumor lysis syndrome following chemotherapy for a uterine epithelioid leiomyosarcoma with focal rhabdomyosarcomatous differentiation. ( 21410837 )
2011
6
A rare case of primitive epithelioid leiomyosarcoma of the conjunctiva. ( 21574810 )
2011
7
Complete remission of recurrent and refractory uterine epithelioid leiomyosarcoma using weekly administration of bevacizumab and temozolomide. ( 21440979 )
2011
8
Epithelioid leiomyosarcoma of the uterus containing sex cord-like elements. ( 19952934 )
2010
9
Epithelioid leiomyosarcoma of the uterus: computed tomography findings. ( 20882890 )
2010
10
Cardiac epithelioid leiomyosarcoma and the role of cardiac imaging in the differentiation of intracardiac masses. ( 20552587 )
2010
11
Epithelioid leiomyosarcoma with rhabdoid features. ( 17943409 )
2007
12
Primary extradural epithelioid leiomyosarcoma of the cervical spine: case report and literature review. ( 16094142 )
2005
13
Epithelioid leiomyosarcoma: case report and review of the literature. ( 16409271 )
2005
14
Epithelioid leiomyosarcoma in the visceral peritoneum of an American badger (Taxidea taxus). ( 15690961 )
2005
15
Epithelioid leiomyosarcoma of the uterine cervix: a case report and review of the literature. ( 15890394 )
2005
16
Epithelioid leiomyosarcoma of the ovary. ( 15863185 )
2005
17
Uterine epithelioid leiomyosarcomas with clear cells: reactivity with HMB-45 and the concept of PEComa. ( 15043315 )
2004
18
Cytological diagnosis of metastatic epithelioid leiomyosarcoma to lymph node--a diagnostic dilemma. ( 14632734 )
2003
19
Epithelioid leiomyosarcoma of the gastrocolic ligament. ( 12658888 )
2003
20
Primary paratesticular epithelioid leiomyosarcoma. ( 12740499 )
2003
21
Epithelioid leiomyosarcoma of the external deep soft tissue. ( 12683863 )
2003
22
A parathyroid hormone-related protein-secreting metastatic epithelioid leiomyosarcoma. A case report and review of the literature. ( 12683897 )
2003
23
Using thalidomide in a patient with epithelioid leiomyosarcoma and Osler-Weber-Rendu disease. ( 11831608 )
2002
24
Epithelioid leiomyosarcoma of the external deep soft tissue. ( 11900575 )
2002
25
Rhabdoid epithelioid leiomyosarcoma of the uterine corpus: a case report and literature review. ( 12232582 )
2002
26
Epithelioid leiomyosarcoma of the uterine cervix. ( 11531304 )
2001
27
Epithelioid leiomyosarcoma of the uterus with oncocytic change. ( 11569929 )
2001
28
Epithelioid leiomyosarcoma in a non-immunocompromised infant: additional differential diagnosis of pediatric "round cell tumors". ( 11048812 )
2000
29
Paraneoplastic pemphigus caused by an epithelioid leiomyosarcoma and associated with fatal respiratory failure. ( 10899680 )
2000
30
Epithelioid leiomyosarcoma of the stomach: report of a case. ( 10714261 )
2000
31
Epithelioid leiomyosarcoma with osteoclast-like giant cells in the rectum. ( 10705403 )
2000
32
Primary epithelioid leiomyosarcoma of bone. Case report and literature review. ( 10335949 )
1999
33
Cytological findings of abdominal malignant leiomyoblastoma (epithelioid leiomyosarcoma) in ascitic fluid; a case report. ( 10588354 )
1999
34
Uterine malignant leiomyoblastoma (epithelioid leiomyosarcoma) during pregnancy. ( 10053121 )
1999
35
Neuron-specific enolase-producing epithelioid leiomyosarcoma with gross vascular invasion and intracardiac involvement. ( 9870863 )
1998
36
Epithelioid lymphangioleiomyomatosis-like tumour of the uterus in a patient without tuberous sclerosis: a lesion mimicking epithelioid leiomyosarcoma. ( 9726062 )
1998
37
Epithelioid leiomyosarcoma of the uterine cervix. ( 9512340 )
1998
38
Epithelioid leiomyosarcoma of the larynx. ( 9702545 )
1998
39
Epithelioid leiomyosarcoma of the skin. ( 9563281 )
1998
40
Fine needle aspiration cytology of gastric epithelioid leiomyosarcoma metastasized to the liver. A case report. ( 9390146 )
1997
41
Malignant plexiform tumor of the uterus: an unusual variant of epithelioid leiomyosarcoma. ( 8910640 )
1996
42
Primary multiple epithelioid leiomyosarcoma of the liver. ( 8975973 )
1996
43
Uterine epithelioid leiomyosarcoma in a pig-tailed macaque. ( 9029402 )
1996
44
Gastric stump carcinoma occurring in a patient with Carney's triad 38 years after partial gastrectomy for epithelioid leiomyosarcoma. ( 7864713 )
1995
45
Epithelioid leiomyosarcoma of the skin and subcutaneous tissue. Clinicopathologic, immunohistochemical, and ultrastructural study of five cases. ( 8116792 )
1994
46
Epithelioid leiomyosarcoma of retroperitoneum with granular cell change. ( 7959652 )
1994
47
Differential alpha-smooth muscle actin expression in a gastric epithelioid leiomyosarcoma in a 14 year old girl. ( 8203266 )
1994
48
A case report of epithelioid leiomyosarcoma of transverse mesocolon: diagnosis and treatment. ( 8253608 )
1993
49
Epithelioid leiomyosarcoma of the oral cavity: report of two cases and review of the literature. ( 8336232 )
1993
50
Epithelioid leiomyosarcoma of the breast: report of a case. ( 8104588 )
1993

Variations for Epithelioid Leiomyosarcoma

Expression for Epithelioid Leiomyosarcoma

Search GEO for disease gene expression data for Epithelioid Leiomyosarcoma.

Pathways for Epithelioid Leiomyosarcoma

Pathways related to Epithelioid Leiomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.62 ACTC1 DES VIM
2
Show member pathways
11.29 DES VIM
3
Show member pathways
10.81 DES VIM
4 10.66 ACTC1 DES VIM

GO Terms for Epithelioid Leiomyosarcoma

Cellular components related to Epithelioid Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.02 ACTC1 DES ENO2 SERPINA3 VIM

Biological processes related to Epithelioid Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament organization GO:0045109 8.96 DES VIM
2 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Molecular functions related to Epithelioid Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 DES VIM

Sources for Epithelioid Leiomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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