Epithelioid Malignant Peripheral Nerve Sheath Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

MalaCards integrated aliases for Epithelioid Malignant Peripheral Nerve Sheath Tumor:

Name: Epithelioid Malignant Peripheral Nerve Sheath Tumor ¹² ¹⁵ ¹⁷ ⁷⁴

Malignant Epithelioid Neoplasm of the Peripheral Nerve Sheath ¹²

Epithelioid Mpnst ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:8353

NCIt ⁵¹ C6561

SNOMED-CT ⁶⁹ 19897006

EFO ¹⁷ EFO_1000245

UMLS ⁷⁴ C1321427

Sources

Summaries for Epithelioid Malignant Peripheral Nerve Sheath Tumor

MalaCards based summary : Epithelioid Malignant Peripheral Nerve Sheath Tumor, also known as malignant epithelioid neoplasm of the peripheral nerve sheath, is related to malignant peripheral nerve sheath tumor and neurilemmomatosis. An important gene associated with Epithelioid Malignant Peripheral Nerve Sheath Tumor is SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1), and among its related pathways/superpathways is Neuroscience. The drugs Doxorubicin and Daunorubicin have been mentioned in the context of this disorder. Affiliated tissues include thyroid, brain and lung.

Sources

Related Diseases for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Diseases related to Epithelioid Malignant Peripheral Nerve Sheath Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 166)

#	Related Disease	Score	Top Affiliating Genes
1	malignant peripheral nerve sheath tumor	30.6	MUC1 NF1 S100B SMARCB1
2	neurilemmomatosis	30.5	NF1 SMARCB1
3	neurilemmoma	29.5	ENO2 NF1 S100B SMARCB1
4	neurofibrosarcoma	10.8
5	malignant triton tumor	10.2	NF1 S100B
6	primary hepatic neuroendocrine carcinoma	10.2	CHGA S100B
7	perineurioma	10.2	MUC1 S100B
8	localized hypertrophic neuropathy	10.2	MUC1 S100B
9	sclerosing perineurioma	10.2	MUC1 S100B
10	reticular perineurioma	10.2	MUC1 S100B
11	neurofibromatosis, type iv, of riccardi	10.2
12	thyroid cancer, nonmedullary, 1	10.2
13	angiosarcoma	10.2
14	thyroid cancer	10.2
15	melanoma	10.2
16	non-functioning pituitary adenoma	10.2	MUC1 S100B
17	functioning pituitary adenoma	10.2	MUC1 S100B
18	pleomorphic xanthoastrocytoma	10.2	CHGA SMARCB1
19	tanycytic ependymoma	10.2	CHGA SMARCB1
20	syringocystadenoma papilliferum	10.2	MUC1 S100B
21	fibrous meningioma	10.2	MUC1 S100B
22	eccrine porocarcinoma	10.2	MUC1 S100B
23	spindle cell rhabdomyosarcoma	10.2	MUC1 S100B
24	aggressive digital papillary adenocarcinoma	10.1	MUC1 S100B
25	myxopapillary ependymoma	10.1	MUC1 S100B
26	monophasic synovial sarcoma	10.1	MUC1 S100B
27	chordoid glioma	10.1	MUC1 S100B
28	spiradenoma	10.1	MUC1 S100B
29	syringoma	10.1	MUC1 S100B
30	pleomorphic liposarcoma	10.1	MUC1 S100B
31	anaplastic ependymoma	10.1	MUC1 S100B
32	papilloma of choroid plexus	10.1	MUC1 S100B
33	spindle cell sarcoma	10.1	MUC1 S100B
34	endocrine gland cancer	10.1	CHGA MUC1
35	myoepithelioma	10.1	S100B SMARCB1
36	dendritic cell tumor	10.1	MUC1 S100B
37	cystadenoma	10.1	CHGA MUC1
38	polymorphous low-grade adenocarcinoma	10.1	MUC1 S100B
39	cellular schwannoma	10.1	NF1 S100B
40	hemangiopericytoma, malignant	10.1	MUC1 S100B
41	clear cell meningioma	10.1	CHGA MUC1
42	pancreatoblastoma	10.1	CHGA MUC1
43	malignant fibroxanthoma	10.1	MUC1 S100B
44	dermoid cyst	10.1	CHGA MUC1
45	sclerosing hemangioma	10.1	CHGA MUC1
46	gastric cardia carcinoma	10.0	CHGA MUC1
47	bednar tumor	10.0	ENO2 S100B
48	middle cerebral artery infarction	10.0	ENO2 S100B
49	head injury	10.0	ENO2 S100B
50	rhabdoid tumor predisposition syndrome 1	10.0	MUC1 SMARCB1

Graphical network of the top 20 diseases related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

Sources

Symptoms & Phenotypes for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Sources

Drugs & Therapeutics for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Drugs for Epithelioid Malignant Peripheral Nerve Sheath Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Doxorubicin

Approved, Investigational

Phase 2, Phase 3

23214-92-8

31703

Synonyms:

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside

(1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside

(8S-cis)-10-((3-amino-2,3,6-Trideoxy-a-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S-cis)-10-((3-amino-2,3,6-Trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

111266-55-8

14-hydroxydaunomycin

14-Hydroxydaunomycin

14-hydroxydaunorubicine

14-Hydroxydaunorubicine

23214-92-8

23257-17-2

24385-08-8

25311-50-6

25316-40-9

25316-40-9 (hydrochloride)

29042-30-6

AC1L1M5T

AC1Q29OJ

adiblastine (hydrochloride salt)

ADM

ADR

adr iablatina (hydrochloride salt)

Adriablastin

Adriablastine

adriablastine (hydrochloride salt)

adriablatina (hydrochloride salt)

Adriacin (hydrochloride salt)

Adriamycin

Adriamycin PFS

Adriamycin PFS (hydrochloride salt)

Adriamycin RDF

Adriamycin RDF (hydrochloride salt)

Adriamycin semiquinone

Adriamycin Semiquinone

Adriblas tina

Adriblastin

Adriblastina

Adriblastina (hydrochloride salt)

Adriblastina (TN)

Adriblastine

adriblatina (hydrochloride salt)

Adrimedac

Aerosolized Doxorubicin

Baxter brand OF doxorubicin hydrochloride

Bedford brand OF doxorubicin hydrochloride

BPBio1_000502

BRD-K92093830-003-04-3

Bristol-myers squibb brand OF doxorubicin hydrochloride

BSPBio_000456

BSPBio_001031

C01661

C27H29NO11

Caelyx

CCRIS 739

Cell pharm brand OF doxorubicin hydrochloride

CHEBI:28748

CHEMBL179

CID31703

Columbia brand OF doxorubicin hydrochloride

Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74

Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120

D03899

DB00997

DM2

Doxil

Doxo

doxo Cell

doxo-Cell

Doxolem

doxorubicin

Doxorubicin

Doxorubicin (USAN/INN)

Doxorubicin [USAN:INN:BAN]

Doxorubicin citrate

Doxorubicin HCl

Doxorubicin hexal

Doxorubicin hydrochloride

Doxorubicin Hydrochloride

Doxorubicin hydrochloride (hydrochloride salt)

Doxorubicin NC

Doxorubicina

Doxorubicina [INN-Spanish]

Doxorubicina ferrer farm

Doxorubicina funk

Doxorubicina tedec

Doxorubicine

Doxorubicine [INN-French]

Doxorubicine baxter

Doxorubicin-hLL1

Doxorubicin-hLL1 conjugate

Doxorubicin-P4/D10

Doxorubicin-P4/D10 conjugate

Doxorubicinum

Doxorubicinum [INN-Latin]

Doxotec

DOX-SL

EINECS 245-495-6

Elan brand OF doxorubicin hydrochloride

Farmablastina (hydrochloride salt)

Farmiblastina

Ferrer brand OF doxorubicin hydrochloride

FI 106

Hexal brand OF doxorubicin hydrochloride

HMS2089H06

HSDB 3070

Hydrochloride, doxorubicin

Hydroxydaunomycin hydrochlor ide (hydrochloride salt)

Hydroxydaunomycin hydrochloride (hydrochloride salt)

Hydroxydaunorubicin

Hydroxydaunorubicin hydrochloride (hydrochloride salt)

JT9100000

Kenfarma brand OF doxorubicin hydrochloride

Lemery brand OF doxorubicin hydrochloride

LMPK13050001

LS-1029

LS-165655

Medac brand OF doxorubicin hydrochloride

MLS000759533

Myocet

NChemBio.2007.10-comp13

nchembio809-comp5

NCI-C01514

NDC 38242-874

Neocorp brand OF doxorubicin hydrochloride

NIOSH/JT9100000

NSC 123127

Onkodox

Onkoworks brand OF doxorubicin hydrochloride

Pfizer brand OF doxorubicin hydrochloride

Prasfarma brand OF doxorubicin hydrochloride

Prestwick0_000438

Prestwick1_000438

Prestwick2_000438

Prestwick3_000438

Probes1_000151

Probes2_000129

RDF Rubex

Resmycin

Ribodoxo

Ribosepharm brand OF doxorubicin hydrochloride

Rubex

Rubex (hydrochloride salt)

SMP1_000106

SPBio_002395

Tedec meiji brand OF doxorubicin hydrochloride

ThermoDox

TLC D-99

Triferric doxorubicin

UNII-80168379AG

Urokit doxo cell

Urokit doxo-cell

2

Daunorubicin

Approved

Phase 2, Phase 3

20830-81-3

30323

Synonyms:

(+)-Daunomycin

(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside

(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside

(7S,9R)-9-Acetyl-7-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione

(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione

(8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione

(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione

(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro--6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione

11006-54-5

11048-29-6

1407-15-4

149541-57-1

20830-81-3

23942-76-9

27576-81-4

28020-80-6

AB00514669

AC1L1JCP

AC1Q29OI

Acetyladriamycin

AI3-52942

Anthracyline

Antibiotics from Streptomyces coeruleorubidus

Antibiotics From Streptomyces Coeruleorubidus

BPBio1_000389

BRD-K43389675-003-02-7

BRN 1445583

BSPBio_000353

C01907

CCRIS 914

Cerubidin

Cerubidine

CHEBI:41977

CHEMBL178

CID30323

D07776

Daunamycin

Daunarubicinum

dauno Rubidomycine

Daunoblastin

Daunoblastine

Daunomycin

Daunomycin Hydrochloride

Daunomycin, Hydrochloride

Daunorrubicina

daunorubicin

Daunorubicin

Daunorubicin (INN)

Daunorubicin (liposomal)

Daunorubicin [INN:BAN]

Daunorubicin Hcl

DAUNORUBICIN HCL

Daunorubicin hydrochloride

Daunorubicin Hydrochloride

Daunorubicin, Hydrochloride

Daunorubicina

Daunorubicine

Daunorubicinum

Daunorubicinum [INN-Latin]

dauno-Rubidomycine

Dauno-Rubidomycine

Daunoxome

DaunoXome

DaunoXome (TN)

DB00694

DM1

EINECS 244-069-7

FI 6339

FI6339

HMS2089H04

HMS2091K06

HSDB 5095

Hydrochloride, daunorubicin

Leukaemomycin C

LMPK13050002

LS-187381

LS-997

MolPort-002-533-961

NCGC00024246-05

NCGC00024246-06

NCGC00025173-01

NChemBio.2007.10-comp14

nchembio723-comp2

NCI-C04693

NSC 83142

NSC-82151

Ondena

Prestwick3_000487

Rcra Waste No. U059

RCRA waste no. U059

RP 13057

Rp 13057 Hydrochloride

Rubidomycin

Rubidomycin Hydrochloride

Rubomycin

Rubomycin C

Tocris-1467

UNII-ZS7284E0ZP

VS-103

3

Ifosfamide

Approved

Phase 2, Phase 3

3778-73-2

3690

Synonyms:

(+-)-Ifosfamid

(+-)-Ifosphamide

(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

(D,L)-Ifosfamide

(R,S)-Ifosphamide

(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,

1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide

1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide

2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd

2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd

2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide

2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide

2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide

2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)

2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide

3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide

3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

3,} 2-oxazaphosphorine oxide

36341-88-5

3778-73-2

84711-20-6

A 4942

AB00513932

AC1L1GHW

AC-2113

Ambap3778-73-2

Asta Z 4942

ASTA Z 4942

BPBio1_000865

BRN 0611835

BSPBio_000785

C07047

CAS-3778-73-2

CCRIS 352

CHEBI:5864

CHEMBL1024

CID3690

Cyfos

D00343

D007069

DB01181

EINECS 223-237-3

HMS1570H07

HMS2090M12

HMS2093N07

Holoxan

Holoxan 1000

HSDB 7023

I06-0494

Ifex

IFEX (TN)

Ifosfamid

Ifosfamida

Ifosfamida [INN-Spanish]

ifosfamide

Ifosfamide

Ifosfamide (JAN/USP/INN)

Ifosfamide [USAN:INN:BAN:JAN]

Ifosfamide sterile

Ifosfamide Sterile

Ifosfamidum

Ifosfamidum [INN-Latin]

Ifosphamide

Ifsofamide

Iphosphamid

Iphosphamid(e)

Iphosphamide

I-phosphamide

I-Phosphamide

iso Endoxan

Iso Endoxan

iso-Endoxan

Isoendoxan

Iso-Endoxan

Isofosfamide

Isophosphamide

isosfamide

Isosfamide

LS-102

LS-99799

Mitoxana

Mitoxana, Ifex, Ifosfamide

MJF 9325

MJF-9325

MLS002154021

MolPort-003-666-704

N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid

N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide

N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine

N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide

Naxamide

NCGC00016639-01

NCGC00179435-01

NCI60_000233

NCI-C01638

NPFAPI-04

NSC 109,724

NSC 109724

NSC109,724

NSC-109,724

NSC109724

NSC-109724

Prestwick0_000833

Prestwick1_000833

Prestwick2_000833

Prestwick3_000833

S1302_Selleck

SMR001233348

SPBio_002706

STL058690

UNII-UM20QQM95Y

WLN: T6NPOTJ AM2G BO B2G

Z 4942

Z4942

Z-4942

4

Mechlorethamine

Approved, Investigational

Phase 2, Phase 3

51-75-2

4033

Synonyms:

.Beta.,.beta.'-Dichlorodiethyl-N-methylamine

1, 5-Dichloro-3-methyl-3-azapentane hydrochloride

126-85-2 (N-oxide)

2,2'-Dichlorodiethyl-methylamine

2,2'-Dichloro-N-me

2,2'-dichloro-N-methyldiethylamine

2,2'-dichloro-N-Methyldiethylamine

2,2'-Dichloro-N-methyldiethylamine

2-Chloro-N-(2-chloroethyl)-N-methylethanamine

302-70-5 (N-oxide, hydrochloride)

51-75-2

55-86-7 (HYDROCHLORIDE)

AC1L1H9H

Antimit

b,Beta'-dichlorodiethyl-N-methylamine

beta,beta'-Dichlorodiethyl-N-methylamine

beta,Beta'-dichlorodiethyl-N-methylamine

bis(2-chloroethyl)methylamine

Bis(2-chloroethyl)methylamine

Bis(b-chloroethyl)methylamine

Bis(beta-chloroethyl) methylamine

Bis(beta-chloroethyl)methylamine

bis(β-chloroethyl)methylamine

Bis(β-chloroethyl)methylamine

BRN 0605323

BSPBio_001947

C07115

C5H11Cl2N

Carolysine

Caryolysin

Caryolysine

CCRIS 447

CHEBI:28925

CHEMBL427

Chloramine (the nitrogen mustard)

Chlorethazine

Chlormethine

Chlormethine (INN)

Chlormethine [INN:BAN]

Chlormethinum

Chlormethinum [INN-Latin]

CID4033

Cloramin

Clormetina

Clormetina [INN-Spanish]

D07671

DB00888

Di(2-chloroethyl)methylamine

Dichlor amine

Dichloren

DivK1c_000759

EINECS 200-120-5

Embechine

Embichin

ENT-25294

HMS1920J15

HMS2091B04

HMS502F21

HN2

HN-2

HSDB 5083

Hydrochloride N-oxide, mechlorethamine

Hydrochloride, mechlorethamine

I14-8708

IBS-L0033631

IDI1_000759

KBio1_000759

KBio2_001369

KBio2_003937

KBio2_006505

KBio3_001447

KBioGR_001448

KBioSS_001369

LS-7559

MBA

Me chloroethamine

Mebichloramine

mechlorethamine

Mechlorethamine

Mechlorethamine hydrochloride

Mechlorethamine hydrochloride N oxide

Mechlorethamine hydrochloride N-oxide

Mechlorethamine N oxide

Mechlorethamine N-oxide

Mechlorethamine oxide

Mechlorethanamine

Mechloroethamine

Mecloretamina

Mecloretamina [Italian]

Merck brand OF mechlorethamine hydrochloride

Merck frosst brand OF mechlorethamine hydrochloride

methylbis(2-chloroethyl)amine

Methylbis(2-chloroethyl)amine

Methylbis(b-chloroethyl)amine

Methylbis(beta-chloroethyl)amine

methylbis(β-chloroethyl)amine

Methylbis(β-chloroethyl)amine

Methylchlorethamine

Methyldi(2-chloroethyl)amine

Mitomen

Mitoxine (*Hydrochloride*)

MolPort-001-785-592

Mustargen

Mustine

Mustine note

Mutagen

N,N-Bis(2-chloroethyl)methylamine

N,N-Bis(2-chloroethyl)-N-methylamine

N,N-Di(chloroethyl)methylamine

NCGC00091835-02

NCGC00091835-03

NCGC00091835-04

NCGC00091835-05

NCI60_041682

NINDS_000759

Nitol (*Hydrochloride*)

Nitrogen mustard

Nitrogen mustard (HN-2)

Nitrogen mustard N oxide

Nitrogen mustard N-oxide

Nitrogranulogen

Nitromin

N-Lost

N-Methyl lost

N-Methyl-2,2'-dichlorodiethylamine

N-methyl-bis(2-chloroethyl)amine

N-Methyl-bis(2-chloroethyl)amine

N-Methyl-bis(b-chloroethyl)amine

N-Methyl-bis(beta-chloroethyl)amine

N-methyl-bis(β-chloroethyl)amine

N-Methyl-bis(β-chloroethyl)amine

N-Methyl-bis-chloraethylamin

N-Methyl-bis-chloraethylamin [German]

N-Methyl-lost

N-Methyl-lost [German]

N-Oxide, mechlorethamine hydrochloride

N-Oxide, nitrogen mustard

NSC 762

NSC762

NSC-762

SPBio_000496

Spectrum_000889

SPECTRUM1500375

Spectrum2_000448

Spectrum3_000484

Spectrum4_000924

Spectrum5_001702

Stickstofflost (*Hydrochloride*)

Stickstofflost (ebewe)

T 1024

T-1024

thyldiethylamine

TL 146

UNII-50D9XSG0VR

β,beta'-dichlorodiethyl-N-methylamine

β,β'-dichlorodiethyl-N-methylamine

5

Cyclophosphamide

Approved, Investigational

Phase 2, Phase 3

50-18-0, 6055-19-2

2907

Synonyms:

(-)-Cyclophosphamide

(+-)-Cyclophosphamide

(RS)-Cyclophosphamide

1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine

1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin

2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

4-Hydroxy-cyclophosphan-mamophosphatide

50-18-0

60007-95-6

6055-19-2 (monohydrate)

75526-90-8

AC1L1EQQ

AI3-26198

Anhydrous cyclophosphamide

Anhydrous, cyclophosphamide

ASTA

Asta B 518

ASTA B518

B 518

B-518

bis(2-Chloroethyl)phosphami de cyclic propanolamide

bis(2-Chloroethyl)phosphamide cyclic propanolamide ester

Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester

BRN 0011744

BSPBio_002099

C 0768

C07888

C7H15Cl2N2O2P

CB 4564

CB-4564

CCRIS 188

CHEBI:4027

CHEMBL32520

CHEMBL88

Ciclofosfamida

Ciclofosfamida [INN-Spanish]

Ciclofosfamide

Ciclophosphamide

Ciclophosphamide [INN]

CID2907

Clafen

Claphene

CP

CPA

CTX

CY

Cycloblastin

Cyclophosphamid

cyclophosphamide

Cyclophosphamide

Cyclophosphamide (anhydrous form)

Cyclophosphamide (anhydrous)

Cyclophosphamide (INN)

Cyclophosphamide (TN)

Cyclophosphamide anhydrous

Cyclophosphamide monohydrate

Cyclophosphamide Monohydrate

Cyclophosphamide Sterile

Cyclophosphamide, (+-)-Isomer

Cyclophosphamide, (R)-isomer

Cyclophosphamide, (S)-isomer

Cyclophosphamides

Cyclophosphamidum

Cyclophosphamidum [INN-Latin]

Cyclophosphan

Cyclophosphane

Cyclophosphanum

Cyclophosphoramide

Cyclostin

Cyklofosfamid

Cyklofosfamid [Czech]

Cytophosphan

Cytophosphane

Cytoxan

Cytoxan (TN)

Cytoxan Lyoph

D,L-Cyclophosphamide

D07760

DB00531

DivK1c_000246

EINECS 200-015-4

Endoxan

Endoxan R

Endoxana

Endoxanal

Endoxan-Asta

Endoxane

Enduxan

EU-0100238

Genoxal

Hexadrin

HMS2090A12

HSDB 3047

IDI1_000246

KBio1_000246

KBio2_001338

KBio2_003906

KBio2_006474

KBio3_001319

KBioGR_000888

KBioSS_001338

Lopac0_000238

Lopac-C-0768

LS-1302

LS-99787

Lyophilized Cytoxan

Mitoxan

MolPort-001-783-420

Monohydrate, cyclophosphamide

N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

NCGC00015209-01

NCGC00015209-03

NCGC00015209-06

NCGC00091741-02

NCGC00091741-03

NCI60_002097

NCI-C04900

Neosar

NINDS_000246

NSC 26271

NSC26271

NSC-26271

NSC273033

NSC273034

Occupation, cyclophosphamide exposure

Procytox

RCRA waste no. U058

Rcra waste number U058

Rcra Waste Number U058

Revimmune

S1217_Selleck

Semdoxan

Sendoxan

Senduxan

SK 20501

SPBio_001071

Spectrum_000858

Spectrum2_001146

Spectrum3_000370

Spectrum4_000304

Spectrum5_000795

STK177249

STOCK2S-91217

UNII-6UXW23996M

WLN: T6MPOTJ BO BN2G2G

Zyklophosphamid

Zyklophosphamid [German]

6

Doxil

Approved June 1999

Phase 2, Phase 3

31703

7

Topoisomerase Inhibitors

Phase 2, Phase 3

8

Antineoplastic Agents, Alkylating

Phase 2, Phase 3

9

Anti-Bacterial Agents

Phase 2, Phase 3

10

Antibiotics, Antitubercular

Phase 2, Phase 3

11

Alkylating Agents

Phase 2, Phase 3

12

Isophosphamide mustard

Phase 2, Phase 3

0

Synonyms:

Ifosfamide mustard

Ifosforamide mustard

IPAM

Iphosphoramide mustard

Isophosphamide mustard

Isophosphoramide mustard

N,N'-di-(2-chloroethyl)phosphorodiamidic acid

NN'-Bis-(2-chloroethyl)phosphate

NN'-Bis-(2-chloroethyl)phosphoric acid

Palifosfamide-tris

zio-201Isophosphamide mustard

13

lysine

Phase 2,Phase 1

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery	Active, not recruiting	NCT02180867	Phase 2, Phase 3	Doxorubicin;Doxorubicin Hydrochloride;Ifosfamide;Pazopanib;Pazopanib Hydrochloride
2	A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma	Recruiting	NCT02601950	Phase 2	Tazemetostat
3	A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma	Recruiting	NCT02601937	Phase 1	Tazemetostat

Search NIH Clinical Center for Epithelioid Malignant Peripheral Nerve Sheath Tumor

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Genetic Tests for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Sources

Anatomical Context for Epithelioid Malignant Peripheral Nerve Sheath Tumor

MalaCards organs/tissues related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

⁴²

Thyroid, Brain, Lung, Kidney, Pituitary, Pineal, Spinal Cord

Sources

Publications for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Articles related to Epithelioid Malignant Peripheral Nerve Sheath Tumor:

(show all 19)

#	Title	Authors	Year
1	Metastatic Epithelioid Malignant Peripheral Nerve Sheath Tumor in a Known Case of Neurofibromatosis-1, Cytomorphological Appearance, and Critical Analysis of Immunohistochemistry. ( 29200699 )	Gupta RK...Das A	2017
2	Fine-needle aspiration cytology of epithelioid malignant peripheral nerve sheath tumor: A case report and review of the literature. ( 26646298 )	Jiwani S...Jeffus S	2016
3	Epithelioid malignant peripheral nerve sheath tumor: clinicopathologic analysis of 63 cases. ( 25602794 )	Jo VY...Fletcher CD	2015
4	A misdiagnosed melanoma: a case of cutaneous epithelioid malignant peripheral nerve sheath tumor. ( 25933073 )	Linos K...Warren S	2015
5	Huge epithelioid malignant peripheral nerve sheath tumor in the left axilla: a case report. ( 26366361 )	Kusumoto E...Momosaki S	2015
6	Rapidly progressive epithelioid malignant peripheral nerve sheath tumor of the vestibular nerve. ( 23988994 )	Kuzmik GA...Bulsara KR	2013
7	Epithelioid malignant peripheral nerve sheath tumor arising in a schwannoma, in a patient with "neuroblastoma-like" schwannomatosis and a novel germline SMARCB1 mutation. ( 22082606 )	Carter JM...Folpe AL	2012
8	Epithelioid malignant peripheral nerve sheath tumor of the uterine corpus. ( 20952276 )	Gulati N...Jambhekar NA	2011
9	Advanced epithelioid malignant peripheral nerve sheath tumor showing complete response to combined surgery and chemotherapy: a case report. ( 22606446 )	Minagawa T...Takahashi H	2011
10	Concurrent epithelioid malignant peripheral nerve sheath tumor and papillary thyroid carcinoma in the treated field of Hodgkin's disease. ( 17972308 )	Yildirim G...El-Naggar AK	2008
11	Epithelioid malignant peripheral nerve sheath tumor in the infraorbital nerve. ( 16550070 )	Prescott DK...Ng JD	2006
12	Epithelioid malignant peripheral nerve sheath tumor. Report of a case with inflammatory infiltration. ( 15991844 )	Matsuda Y...Imaida K	2005
13	Epithelioid malignant peripheral nerve sheath tumor involving maxillary sinus. ( 16382783 )	Izycka-Swieszewska E...Jaskiewicz K	2005
14	Immunohistochemical diagnosis of a rare case of epithelioid malignant peripheral nerve sheath tumor with multiple metastases. ( 15592781 )	Tsuchiya D...Yamashita H	2004
15	Expanding the spectrum of malignant change in schwannomas: epithelioid malignant change, epithelioid malignant peripheral nerve sheath tumor, and epithelioid angiosarcoma: a study of 17 cases. ( 11145248 )	McMenamin ME...Fletcher CD	2001
16	Intraosseous epithelioid malignant peripheral nerve sheath tumor of the phalanx. Case report. ( 10230694 )	Hirokawa M...Manabe T	1999
17	Purely epithelioid malignant peripheral nerve sheath tumor of the vulva. ( 9142667 )	Lee YS...Shim SI	1997
18	Fine-needle aspiration of epithelioid malignant peripheral nerve sheath tumor (epithelioid malignant schwannoma). ( 9285192 )	Dodd LG...Layfield LJ	1997
19	The purely epithelioid malignant peripheral nerve sheath tumor. ( 2425646 )	DiCarlo EF...Erlandson RA	1986

Sources

Genes for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Genes related to Epithelioid Malignant Peripheral Nerve Sheath Tumor (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	SMARCB1	SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1	Protein Coding	24.13	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	CHGA	Chromogranin A	Protein Coding	20.6	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	S100B	S100 Calcium Binding Protein B	Protein Coding	17.91	GeneCards inferred via : Publications (show sections)
4	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	17.56	GeneCards inferred via : Publications (show sections)
5	ENO2	Enolase 2	Protein Coding	14.98	DISEASES inferred ¹⁵
6	NF1	Neurofibromin 1	Protein Coding	14.76	DISEASES inferred ¹⁵

Sources

Variations for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Sources

Expression for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Search GEO for disease gene expression data for Epithelioid Malignant Peripheral Nerve Sheath Tumor.

Sources

Pathways for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Pathways related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ⁴	11.33	ENO2 NF1 S100B

Sources

GO Terms for Epithelioid Malignant Peripheral Nerve Sheath Tumor

Biological processes related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of histone H4 acetylation	GO:0090240	8.62	MUC1 SMARCB1

Molecular functions related to Epithelioid Malignant Peripheral Nerve Sheath Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	p53 binding	GO:0002039	8.62	MUC1 SMARCB1

Sources

Sources for Epithelioid Malignant Peripheral Nerve Sheath Tumor

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia