MCID: EPT012
MIFTS: 47

Epithelioid Sarcoma

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Epithelioid Sarcoma

MalaCards integrated aliases for Epithelioid Sarcoma:

Name: Epithelioid Sarcoma 12 53 59 15
Epithelioid Cell Sarcoma 12
Sarcoma, Epithelioid 73
Sarcoma Epithelioid 55

Characteristics:

Orphanet epidemiological data:

59
epithelioid sarcoma
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe); Age of onset: Adolescent,Adult,Childhood; Age of death: young Adult;

Classifications:



External Ids:

Disease Ontology 12 DOID:6193
MeSH 44 D012509
NCIt 50 C3714
SNOMED-CT 68 59238007
Orphanet 59 ORPHA293202
UMLS via Orphanet 74 C0205944
ICD10 via Orphanet 34 C49.9
UMLS 73 C0205944

Summaries for Epithelioid Sarcoma

NIH Rare Diseases : 53 Epithelioid sarcoma is a rare cancer that most often occurs in the soft tissue of the fingers, hands and forearms of young adults.  It may also be found in the legs, trunk, head or neck regions.  It is rare in young children and adults, and it occurs more frequently in men.  Epithelioid sarcoma begins as a painless, firm growth or bump that may be accompanied by an open wound (ulceration) in the skin covering the growth.  It is considered an aggressive cancer because it has a high chance of regrowing after treatment (a recurrence), or spreading to surrounding tissues or more distant parts of the body (a metastasis).  Epithelioid sarcoma is first treated with surgery to remove all the cancer cells (wide local excision).  Amputation of part of the affected limb may be needed in severe cases.  Radiation therapy or chemotherapy may also be used to destroy any cancer cells not removed during surgery.

MalaCards based summary : Epithelioid Sarcoma, also known as epithelioid cell sarcoma, is related to rhabdoid cancer and malignant fibroxanthoma. An important gene associated with Epithelioid Sarcoma is SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1), and among its related pathways/superpathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. The drugs Doxorubicin and Mechlorethamine have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and bone, and related phenotypes are cardiovascular system and embryo

Wikipedia : 76 Epithelioid sarcoma is a rare soft tissue sarcoma arising from mesenchymal tissue and characterized by... more...

Related Diseases for Epithelioid Sarcoma

Diseases in the Epithelioid Sarcoma family:

Central Epithelioid Sarcoma Adult Epithelioid Sarcoma

Diseases related to Epithelioid Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 207)
# Related Disease Score Top Affiliating Genes
1 rhabdoid cancer 31.2 MUC1 SMARCB1 VIM
2 malignant fibroxanthoma 30.8 MUC1 VIM
3 vulvar sarcoma 30.7 KRT7 SMARCB1
4 hemangiopericytoma, malignant 30.6 MUC1 VIM
5 myoepithelioma 30.3 SMARCB1 VIM
6 monophasic synovial sarcoma 30.2 KRT7 MUC1 VIM
7 pleomorphic liposarcoma 30.2 KRT8 MUC1 VIM
8 angiosarcoma 30.1 KRT8 MUC1 VIM
9 sarcoma, synovial 30.1 KRT7 KRT8 MUC1 VIM
10 chordoma 29.7 KRT7 MUC1 SMARCB1 VIM
11 central epithelioid sarcoma 12.2
12 pediatric epithelioid sarcoma 12.2
13 vulvar proximal-type epithelioid sarcoma 12.1
14 peripheral epithelioid sarcoma 12.0
15 adult epithelioid sarcoma 12.0
16 hemangioendothelioma 11.4
17 epithelioid cell synovial sarcoma 11.3
18 sarcoma 11.0
19 rhabdoid meningioma 10.9 SMARCB1 VIM
20 epithelioid malignant peripheral nerve sheath tumor 10.8 MUC1 SMARCB1
21 malignant peritoneal mesothelioma 10.8 MUC1 VIM
22 papillary tumor of the pineal region 10.8 MUC1 VIM
23 ossifying fibromyxoid tumor 10.8 MUC1 VIM
24 fibrous meningioma 10.8 MUC1 VIM
25 chordoid meningioma 10.8 MUC1 VIM
26 syringocystadenoma papilliferum 10.8 MUC1 VIM
27 endometrial mucinous adenocarcinoma 10.8 MUC1 VIM
28 biphasic synovial sarcoma 10.8 MUC1 VIM
29 adenofibroma 10.8 MUC1 VIM
30 adenoid squamous cell carcinoma 10.8 KRT7 VIM
31 myxopapillary ependymoma 10.8 MUC1 VIM
32 syringoma 10.8 MUC1 VIM
33 solid adenocarcinoma with mucin production 10.8 KRT7 MUC1
34 papillary adenoma 10.8 KRT7 VIM
35 benign metastasizing leiomyoma 10.8 KRT7 VIM
36 endosalpingiosis 10.8 KRT7 MUC1
37 desmoplastic small round cell tumor 10.8 MUC1 VIM
38 perivascular epithelioid cell tumor 10.8 MUC1 VIM
39 bile duct mucoepidermoid carcinoma 10.8 KRT7 MUC1
40 anaplastic ependymoma 10.8 MUC1 VIM
41 middle ear adenoma 10.8 KRT7 MUC1
42 reticulum cell sarcoma 10.8 MUC1 VIM
43 mucinous bronchioloalveolar adenocarcinoma 10.8 KRT7 MUC1
44 medulloepithelioma 10.8 KRT7 VIM
45 metanephric adenoma 10.8 KRT7 VIM
46 sertoli cell tumor 10.8 MUC1 VIM
47 adenomatoid tumor 10.8 KRT7 VIM
48 mesenchymal chondrosarcoma 10.7 MUC1 VIM
49 bile duct cystadenocarcinoma 10.7 KRT7 MUC1
50 apocrine adenocarcinoma 10.7 KRT7 MUC1

Graphical network of the top 20 diseases related to Epithelioid Sarcoma:



Diseases related to Epithelioid Sarcoma

Symptoms & Phenotypes for Epithelioid Sarcoma

MGI Mouse Phenotypes related to Epithelioid Sarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.7 CDH5 KRT1 KRT8 MB SALL4 SMARCB1
2 embryo MP:0005380 9.43 CDH5 KRT8 MB SALL4 SMARCB1 VIM
3 homeostasis/metabolism MP:0005376 9.23 CDH5 KRT1 KRT7 KRT8 MB SALL4

Drugs & Therapeutics for Epithelioid Sarcoma

Drugs for Epithelioid Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 76)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 23214-92-8 31703
2
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 51-75-2 4033
3
Ifosfamide Approved Phase 3,Phase 2,Phase 1,Not Applicable 3778-73-2 3690
4
Lenograstim Approved, Investigational Phase 3,Phase 2 135968-09-1
5
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
6
Carboplatin Approved Phase 3,Phase 2 41575-94-4 10339178 498142 38904
7
Vincristine Approved, Investigational Phase 3,Phase 2 2068-78-2, 57-22-7 5978
8
Cyclophosphamide Approved, Investigational Phase 3,Phase 2 50-18-0, 6055-19-2 2907
9
Dactinomycin Approved, Investigational Phase 3,Phase 2 50-76-0 2019 457193
10
Epirubicin Approved Phase 3,Phase 2 56420-45-2 41867
11
Trabectedin Approved, Investigational Phase 2, Phase 3 114899-77-3 108150
12
Cyproheptadine Approved Phase 3 129-03-3 2913
13
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
14
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1,Not Applicable 31703
15
Isophosphamide mustard Phase 3,Phase 2,Phase 1,Not Applicable 0
16 Alkylating Agents Phase 3,Phase 2,Phase 1,Not Applicable
17 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1,Not Applicable
18 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1,Not Applicable
19 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1,Not Applicable
20 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1,Not Applicable
21 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
22 Etoposide phosphate Phase 3,Phase 2
23 Immunosuppressive Agents Phase 3,Phase 2
24 Anti-Infective Agents Phase 3,Phase 2
25 Antirheumatic Agents Phase 3,Phase 2
26 Antimitotic Agents Phase 3,Phase 2
27 Antineoplastic Agents, Phytogenic Phase 3,Phase 2
28
Histamine Phosphate Phase 3 51-74-1 65513
29 Serotonin Agents Phase 3
30 Serotonin Antagonists Phase 3
31 Gastrointestinal Agents Phase 3
32 Neurotransmitter Agents Phase 3
33 Histamine Antagonists Phase 3
34 Histamine H1 Antagonists Phase 3
35 Dermatologic Agents Phase 3
36 Anti-Allergic Agents Phase 3
37 Antipruritics Phase 3
38
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
39
Dacarbazine Approved, Investigational Phase 2 4342-03-4 5351166
40
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
41
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
42
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
43
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
44
Everolimus Approved Phase 2 159351-69-6 6442177
45
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353
46
Romidepsin Approved, Investigational Phase 2 128517-07-7 5352062
47
Gemcitabine Approved Phase 2 95058-81-4 60750
48
Dasatinib Approved, Investigational Phase 2 302962-49-8 3062316
49
Nicotinamide Approved, Investigational, Nutraceutical Phase 2 98-92-0 936
50
Niacin Approved, Investigational, Nutraceutical Phase 2 59-67-6 938

Interventional clinical trials:

(show all 35)
# Name Status NCT ID Phase Drugs
1 Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue Sarcoma Unknown status NCT00334854 Phase 3 doxorubicin hydrochloride;ifosfamide
2 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00346164 Phase 3 doxorubicin hydrochloride;ifosfamide
3 Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00061984 Phase 3 doxorubicin hydrochloride;ifosfamide
4 Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis Completed NCT00091351 Phase 3
5 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3 doxorubicin hydrochloride;ifosfamide;isolated perfusion
6 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3 carboplatin;cyclophosphamide;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
7 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3 Doxorubicin Hydrochloride;Ifosfamide;Pazopanib Hydrochloride
8 Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma Active, not recruiting NCT00423618 Phase 3
9 Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma Terminated NCT01189253 Phase 2, Phase 3 doxorubicin hydrochloride;trabectedin
10 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
11 Brostallicin or Doxorubicin as First-Line Therapy in Treating Patients With Relapsed, Refractory, or Metastatic Soft Tissue Sarcoma Unknown status NCT00410462 Phase 2 brostallicin;doxorubicin hydrochloride
12 Temozolomide in Treating Patients With Advanced Soft Tissue Sarcoma Unknown status NCT00003718 Phase 2 temozolomide
13 Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma Completed NCT01614795 Phase 2 Temsirolimus
14 Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma Completed NCT00245102 Phase 2 sorafenib tosylate
15 Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma Completed NCT00112463 Phase 2 romidepsin
16 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2 Gamma-Secretase Inhibitor RO4929097;Vismodegib
17 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2 BI 2536
18 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2 sunitinib malate
19 Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00003939 Phase 2 trabectedin
20 STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma Completed NCT00006357 Phase 1, Phase 2 imatinib mesylate
21 Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors Completed NCT00025441 Phase 2 carboplatin;cyclophosphamide;doxorubicin hydrochloride;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
22 A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma Recruiting NCT02601950 Phase 2 Tazemetostat
23 Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Recruiting NCT02584309 Phase 2 Dexrazoxane;Doxorubicin;Olaratumab
24 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2 Gemcitabine Hydrochloride;Pazopanib Hydrochloride
25 Trial of Dasatinib in Advanced Sarcomas Active, not recruiting NCT00464620 Phase 2 Dasatinib
26 Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma Terminated NCT00740597 Phase 2
27 Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma Completed NCT00720174 Phase 1 Doxorubicin Hydrochloride
28 Liposomal Doxorubicin Plus Ifosfamide in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00030784 Phase 1 ifosfamide;pegylated liposomal doxorubicin hydrochloride
29 Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery Recruiting NCT03009201 Phase 1 Doxorubicin;Ribociclib
30 A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma Active, not recruiting NCT02601937 Phase 1 Tazemetostat
31 Tissue Sample Collection From Patients With Soft Tissue Sarcoma of the Arms, Hands, Legs, or Feet Treated on Clinial Trial CRUK-VORTEX Unknown status NCT00900211
32 Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas Completed NCT01567046
33 An Observational Study on Epithelioid Sarcoma Active, not recruiting NCT03099681
34 PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma Active, not recruiting NCT00346125 Not Applicable doxorubicin hydrochloride;ifosfamide;pegylated liposomal doxorubicin hydrochloride
35 Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma Withdrawn NCT00334984 Not Applicable glutamine

Search NIH Clinical Center for Epithelioid Sarcoma

Genetic Tests for Epithelioid Sarcoma

Anatomical Context for Epithelioid Sarcoma

MalaCards organs/tissues related to Epithelioid Sarcoma:

41
Skin, Lung, Bone, Lymph Node, Tongue, Cervix, Brain

Publications for Epithelioid Sarcoma

Articles related to Epithelioid Sarcoma:

(show top 50) (show all 457)
# Title Authors Year
1
Intramuscular Epithelioid Sarcoma Presenting as Extrinsic Flexor Tightness inA the Forearm. ( 29602652 )
2018
2
Anthracycline, Gemcitabine, and Pazopanib in Epithelioid Sarcoma: A Multi-institutional Case Series. ( 29800950 )
2018
3
Clinicopathological analysis of myxoid proximal-type epithelioid sarcoma. ( 29068073 )
2018
4
Cytomorphology of proximal epithelioid sarcoma in the paratesticular location. ( 29508464 )
2018
5
Proximal-type epithelioid sarcoma of the vulva: Cytopathological diagnosis of a rare neoplasm. ( 29683530 )
2018
6
European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Experience with Advanced/Metastatic Epithelioid Sarcoma Patients Treated in Prospective Trials: Clinical Profile and Response to Systemic Therapy. ( 29550245 )
2018
7
Epithelioid Sarcoma Presenting as Recurrent Thumb Ulcer: a Lesson to Learn. ( 29887710 )
2018
8
An unusual presentation of pneumothorax associated with cystic lung metastasis from epithelioid sarcoma: A case report and review of the literature. ( 29541222 )
2018
9
SWI/SNF Chromatin-remodeling Complex Status in SMARCB1/INI1-preserved Epithelioid Sarcoma. ( 29309303 )
2018
10
Epithelioid sarcoma of the plantar fascia mimicking Morbus Ledderhose - A severe pitfall for clinical and histopathological misinterpretation. ( 29202999 )
2017
11
Proximal-Type Epithelioid Sarcoma: Report of an Unusual Case in the Uterine Cervix. ( 28381140 )
2017
12
Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma - a rare vascular neoplasm with deceptive morphology and distinctive immunophenotype. ( 29279595 )
2017
13
Proximal-Type Epithelioid Sarcoma in Skull Base: a Pathological Diagnosis Challenge with Other Intracranial Tumors. ( 29076075 )
2017
14
Phase 2 study of dasatinib in patients with alveolar soft part sarcoma, chondrosarcoma, chordoma, epithelioid sarcoma, or solitary fibrous tumor. ( 27696380 )
2017
15
Emmprin, released as a microvesicle in epithelioid sarcoma, interacts with fibroblasts. ( 28498412 )
2017
16
Can radical margins improve prognosis in primary and localized epithelioid sarcoma of the extremities? ( 29266231 )
2017
17
Management of Epithelioid Sarcoma of the Inguinal Region with Vascular Invasion. ( 28659687 )
2017
18
Different subtypes of epithelioid sarcoma and their clinical implication: long-term multi-institutional experience with a rare sarcoma. ( 28233450 )
2017
19
Retroperitoneal epithelioid sarcoma: A case report. ( 29290913 )
2017
20
Cutaneous pseudomyogenic (epithelioid sarcoma-like) haemangioendothelioma FOSB immunohistochemistry demonstrating the SERPINE1-FOSB fusion gene. ( 28622428 )
2017
21
INI Expressing Epithelioid Sarcoma with Osteoclastic Giant Cells in a Child: A Case Report with Summary of Prior Published Cases. ( 28541826 )
2017
22
Expression of CD34 and I^-Catenin in Malignant Rhabdoid Tumor of the Liver Mimicking Proximal-Type Epithelioid Sarcoma. ( 28683521 )
2017
23
A typical presentation of primary pulmonary epithelioid sarcoma misdiagnosed as non-small cell lung cancer. ( 28078765 )
2017
24
Cutaneous syncytial myoepithelioma: A recently described neoplasm which may mimic nevoid melanoma and epithelioid sarcoma. ( 28708250 )
2017
25
Management of Epithelioid Sarcoma of the Inguinal Region with Vascular Invasion. ( 27574351 )
2016
26
Epithelioid sarcoma-like hemangioendothelioma on the chest wall. ( 27493191 )
2016
27
Primary epithelioid sarcoma of the kidney and adrenal gland: report of 2 cases with immunohistochemical and molecular cytogenetic studies. ( 27769872 )
2016
28
Proximal-type epithelioid sarcoma: a new case report and literature review. ( 27800093 )
2016
29
Spectrum of cytopathologic features of epithelioid sarcoma in a series of 7 uncommon cases with immunohistochemical results, including loss of INI1/SMARCB1 in two test cases. ( 27145123 )
2016
30
Osteoclast-rich, proximal-type epithelioid sarcoma: clinicopathologic features of 3 unusual cases expanding the histomorphological spectrum. ( 27040929 )
2016
31
Epigenetic regulation of SMARCB1 By miR-206, -381 and -671-5p is evident in a variety of SMARCB1 immunonegative soft tissue sarcomas, while miR-765 appears specific for epithelioid sarcoma. A miRNA study of 223 soft tissue sarcomas. ( 27223121 )
2016
32
Epithelioid sarcoma of the vulva and its clinical implication: A case report and review of the literature. ( 26937486 )
2016
33
Primary Epithelioid Sarcoma of the Zygomatic Bone. ( 27442626 )
2016
34
Metastatic epithelioid sarcoma revealed with (18)F-FDGA PET/CT imaging. ( 27922155 )
2016
35
Aortic Endograft and Epithelioid Sarcoma: A Random Association or Causality? ( 27391643 )
2016
36
Proximal epithelioid sarcoma after a history of malignant melanoma: a diagnostic challenge. ( 27188643 )
2016
37
Epithelioid sarcoma with spontaneous pneumothorax and massive pleural effusion. ( 26767876 )
2016
38
Epithelioid Sarcoma: Diagnostic Features and Genetics. ( 26645461 )
2016
39
Primary proximal epithelioid sarcoma of the lung successfully treated with pneumonectomy and adjuvant chemotherapy. ( 27045049 )
2016
40
Epithelioid sarcoma with multiple lesions on the left arm: a case report. ( 27776545 )
2016
41
&amp;quot;Malignant&amp;quot; foot drop: Enzinger epithelioid sarcoma of the common fibular nerve. ( 27061383 )
2016
42
Expression of F-actin-capping protein subunit beta, CAPZB, is associated with cell growth and motility in epithelioid sarcoma. ( 26965049 )
2016
43
Epithelioid Sarcoma: Opportunities for Biology-Driven Targeted Therapy. ( 26347853 )
2015
44
Primary synovial epithelioid sarcoma of the knee: distinctly unusual location leading to its confusion with pigmented villonodular synovitis. ( 25801084 )
2015
45
Fine-needle-aspiration cytology of a proximal type epithelioid sarcoma: A case report. ( 26138930 )
2015
46
A novel treatment for bone lesions of multifocal epithelioid sarcoma-like hemangioendothelioma. ( 25564226 )
2015
47
Epithelioid Sarcoma in the Cervical Spine: A Case Report. ( 26512275 )
2015
48
Epithelioid sarcoma on the face in an elderly patient. ( 25950524 )
2015
49
Prognostic Value of Relevant Clinicopathologic Variables in Epithelioid Sarcoma: A Multi-Institutional Retrospective Study of 44 Patients. ( 25663591 )
2015
50
Single-Staged Multilevel Spondylectomy for En Bloc Resection of an Epithelioid Sarcoma With Intradural Extension in the Cervical Spine: Technical Case Report. ( 26308628 )
2015

Variations for Epithelioid Sarcoma

Cosmic variations for Epithelioid Sarcoma:

9
(show all 22)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM43687 TP53 soft tissue,leg,sarcoma,NS c.641A>G p.H214R 17:7674890-7674890 11
2 COSM11333 TP53 soft tissue,leg,sarcoma,NS c.499C>T p.Q167* 17:7675113-7675113 11
3 COSM4774989 SH2B3 soft tissue,leg,sarcoma,NS c.232G>A p.E78K 12:111418377-111418377 11
4 COSM6954536 NUP93 soft tissue,leg,sarcoma,NS c.116C>T p.A39V 16:56748363-56748363 11
5 COSM575 NRAS soft tissue,skin,sarcoma,NS c.38G>C p.G13A 1:114716123-114716123 11
6 COSM487 HRAS soft tissue,neck,sarcoma,NS c.37G>A p.G13S 11:534286-534286 11
7 COSM2923082 ANKRD11 soft tissue,leg,sarcoma,NS c.2882G>T p.R961L 16:89283660-89283660 11
8 COSM121083 soft tissue,leg,sarcoma,NS c.220C>T p.Q74* 17:7675113-7675113 11
9 COSM1640840 soft tissue,leg,sarcoma,NS c.641A>G p.H214R 17:7674890-7674890 11
10 COSM307279 soft tissue,leg,sarcoma,NS c.641A>G p.H214R 17:7674890-7674890 11
11 COSM2744872 soft tissue,leg,sarcoma,NS c.499C>T p.Q167* 17:7675113-7675113 11
12 COSM3937613 soft tissue,leg,sarcoma,NS c.499C>T p.Q167* 17:7675113-7675113 11
13 COSM307282 soft tissue,leg,sarcoma,NS c.362A>G p.H121R 17:7674890-7674890 11
14 COSM121082 soft tissue,leg,sarcoma,NS c.499C>T p.Q167* 17:7675113-7675113 11
15 COSM121084 soft tissue,leg,sarcoma,NS c.103C>T p.Q35* 17:7675113-7675113 11
16 COSM3388198 soft tissue,leg,sarcoma,NS c.641A>G p.H214R 17:7674890-7674890 11
17 COSM121081 soft tissue,leg,sarcoma,NS c.499C>T p.Q167* 17:7675113-7675113 11
18 COSM307280 soft tissue,leg,sarcoma,NS c.641A>G p.H214R 17:7674890-7674890 11
19 COSM307281 soft tissue,leg,sarcoma,NS c.245A>G p.H82R 17:7674890-7674890 11
20 COSM28757 GNAQ skin,hand,benign melanocytic nevus,epithelioid c.626A>T p.Q209L 9:77794572-77794572 10
21 COSM33806 SMARCB1 soft tissue,proximal,epithelioid sarcoma,NS c.769C>T p.Q257* 22:23816910-23816910 7
22 COSM6962232 DICER1 soft tissue,proximal,epithelioid sarcoma,NS c.4859G>T p.S1620I 14:95096061-95096061 7

Expression for Epithelioid Sarcoma

Search GEO for disease gene expression data for Epithelioid Sarcoma.

Pathways for Epithelioid Sarcoma

Pathways related to Epithelioid Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.75 KRT7 KRT8 MUC1 VIM
2
Show member pathways
11.05 CAPZB KRT1 KRT7 KRT8 VIM
3 10.66 CDH5 VIM

GO Terms for Epithelioid Sarcoma

Cellular components related to Epithelioid Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.7 CAPZB KRT1 KRT7 KRT8 MB MUC1
2 keratin filament GO:0045095 9.13 KRT1 KRT7 KRT8
3 intermediate filament GO:0005882 8.92 KRT1 KRT7 KRT8 VIM

Biological processes related to Epithelioid Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heart development GO:0007507 9.5 CDH5 MB SALL4
2 viral process GO:0016032 9.46 KRT7 KRT8 SMARCB1 VIM
3 keratinization GO:0031424 9.43 KRT1 KRT7 KRT8
4 cornification GO:0070268 9.13 KRT1 KRT7 KRT8
5 positive regulation of histone H4 acetylation GO:0090240 8.62 MUC1 SMARCB1

Molecular functions related to Epithelioid Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 8.92 KRT1 KRT7 KRT8 VIM

Sources for Epithelioid Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
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62 PubMed
64 QIAGEN
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