MCID: EPS023
MIFTS: 42

Epstein-Barr Virus-Associated Gastric Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Epstein-Barr Virus-Associated Gastric Carcinoma

MalaCards integrated aliases for Epstein-Barr Virus-Associated Gastric Carcinoma:

Name: Epstein-Barr Virus-Associated Gastric Carcinoma 60
Ebv-Associated Gastric Carcinoma 60
Ebvagc 60

Characteristics:

Orphanet epidemiological data:

60
epstein-barr virus-associated gastric carcinoma
Inheritance: Multigenic/multifactorial;

Classifications:



External Ids:

ICD10 via Orphanet 35 C16.0 C16.2
Orphanet 60 ORPHA313920

Summaries for Epstein-Barr Virus-Associated Gastric Carcinoma

MalaCards based summary : Epstein-Barr Virus-Associated Gastric Carcinoma, also known as ebv-associated gastric carcinoma, is related to tongue disease and adult hepatocellular carcinoma. An important gene associated with Epstein-Barr Virus-Associated Gastric Carcinoma is SNHG8 (Small Nucleolar RNA Host Gene 8), and among its related pathways/superpathways are Innate Immune System and HIV Life Cycle. Affiliated tissues include t cells, kidney and colon, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related Diseases for Epstein-Barr Virus-Associated Gastric Carcinoma

Diseases related to Epstein-Barr Virus-Associated Gastric Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 118)
# Related Disease Score Top Affiliating Genes
1 tongue disease 10.4 CDH1 CDKN2A CTNNB1
2 adult hepatocellular carcinoma 10.3 CTNNB1 PIK3CA
3 prostate transitional cell carcinoma 10.3 CTNNB1 PIK3CA
4 pharynx cancer 10.3 CDH1 CDKN2A CTNNB1
5 cervix disease 10.3 CDH1 CDKN2A CTNNB1
6 gastritis 10.3
7 atrophic gastritis 10.3
8 cervical squamous cell carcinoma 10.3 CDH1 CDKN2A CTNNB1
9 large intestine adenocarcinoma 10.3 CDH1 CTNNB1
10 chronic venous leg ulcers 10.3 FAS FASLG
11 tongue cancer 10.3 CDH1 CDKN2A CTNNB1
12 punctate inner choroidopathy 10.3 IL10 TNF
13 type ii mixed cryoglobulinemia 10.3 FAS FASLG
14 tropical endomyocardial fibrosis 10.3 IL10 TNF
15 endomyocardial fibrosis 10.3 IL10 TNF
16 central nervous system lymphoma 10.3 CD274 CDKN2A IL10
17 colorectal adenocarcinoma 10.3 CDH1 CTNNB1 MUC2
18 anaplastic thyroid cancer 10.2 CDH1 CTNNB1 PIK3CA
19 gallbladder adenoma 10.2 CDKN2A CTNNB1
20 uterine carcinosarcoma 10.2 CDH1 CTNNB1 PIK3CA
21 signet ring cell adenocarcinoma 10.2 CDH1 MUC2 MUC6
22 tumor of exocrine pancreas 10.2 MUC2 MUC6
23 small intestine adenocarcinoma 10.2 MUC2 MUC6
24 bronchiolo-alveolar adenocarcinoma 10.2 CDH1 MUC2 MUC6
25 pancreatic intraductal papillary-mucinous neoplasm 10.2 MUC2 MUC6
26 tongue squamous cell carcinoma 10.2 CDH1 CDKN2A CTNNB1
27 orofacial granulomatosis 10.2 FLG IL10 TNF
28 adenocarcinoma 10.2 CDH1 CDKN2A CTNNB1 PIK3CA
29 pernicious anemia 10.2
30 nasopharyngeal carcinoma 10.2
31 lymphoma 10.2
32 neuroendocrine carcinoma 10.2
33 lymphosarcoma 10.2
34 uterine anomalies 10.2 CDH1 CDKN2A CTNNB1 PIK3CA
35 pancreatic ductal carcinoma 10.2 CDKN2A MUC2 MUC6
36 tonsil cancer 10.2 CDH1 CDKN2A TNF
37 multifocal choroiditis 10.2 IL10 TNF
38 allergic contact dermatitis 10.1 FLG IL10 TNF
39 contact dermatitis 10.1 FLG IL10 TNF
40 endocrine gland cancer 10.1 CDH1 CDKN2A CTNNB1
41 tungiasis 10.1 IL10 TNF
42 nasopharyngeal disease 10.1 CDH1 CDKN2A CTNNB1 PSMB9
43 lymphocytic gastritis 10.1 FAS FASLG
44 autoimmune disease of musculoskeletal system 10.1 IL10 IRF5 TNF
45 anal squamous cell carcinoma 10.1 CDKN2A PIK3CA TP73
46 bladder urothelial carcinoma 10.1 CDH1 CTNNB1 FAS PIK3CA
47 acute graft versus host disease 10.1 FASLG IL10 TNF
48 idiopathic neutropenia 10.1 FASLG IL10 TNF
49 mediastinal malignant lymphoma 10.1 CD274 JAK2 PDCD1LG2
50 adamantinoma of long bones 10.1 CDH1 CDKN2A CTNNB1 PIK3CA

Graphical network of the top 20 diseases related to Epstein-Barr Virus-Associated Gastric Carcinoma:



Diseases related to Epstein-Barr Virus-Associated Gastric Carcinoma

Symptoms & Phenotypes for Epstein-Barr Virus-Associated Gastric Carcinoma

GenomeRNAi Phenotypes related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.44 CDKN2A FAS IL10 PSMB9 TNF TP73
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.44 CDKN2A FAS FASLG IL10 PSMB9 TNF

MGI Mouse Phenotypes related to Epstein-Barr Virus-Associated Gastric Carcinoma:

47 (show all 17)
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 10.41 CD274 CDH1 CDKN2A CTNNB1 FAS FASLG
2 homeostasis/metabolism MP:0005376 10.4 CD274 CDH1 CDKN2A CTNNB1 FAS FASLG
3 cellular MP:0005384 10.37 CD274 CDH1 CDKN2A CTNNB1 FAS FASLG
4 hematopoietic system MP:0005397 10.36 CD274 CDKN2A CTNNB1 FAS FASLG IL10
5 endocrine/exocrine gland MP:0005379 10.34 CDH1 CDKN2A CTNNB1 FAS FASLG IL10
6 cardiovascular system MP:0005385 10.31 CDH1 CDKN2A CTNNB1 FAS FASLG IL10
7 digestive/alimentary MP:0005381 10.29 CDH1 CDKN2A CTNNB1 FAS FASLG IL10
8 mortality/aging MP:0010768 10.25 CD274 CDH1 CDKN2A CTNNB1 FAS FASLG
9 embryo MP:0005380 10.19 CDH1 CDKN2A CTNNB1 IL10 JAK2 PIK3CA
10 neoplasm MP:0002006 10.18 CDH1 CDKN2A CTNNB1 FAS FASLG IL10
11 integument MP:0010771 10.16 CD274 CDH1 CDKN2A CTNNB1 FAS FASLG
12 liver/biliary system MP:0005370 10.03 CDKN2A CTNNB1 FAS FASLG IL10 JAK2
13 reproductive system MP:0005389 10 CDH1 CDKN2A CTNNB1 FAS FASLG IL10
14 no phenotypic analysis MP:0003012 9.92 CD274 CDH1 CDKN2A CTNNB1 IL10 PDCD1LG2
15 respiratory system MP:0005388 9.76 CDKN2A CTNNB1 FAS FASLG IL10 TNF
16 skeleton MP:0005390 9.7 CD274 CDKN2A CTNNB1 FAS FASLG IL10
17 vision/eye MP:0005391 9.28 CDKN2A CTNNB1 FAS FASLG IL10 MUC5AC

Drugs & Therapeutics for Epstein-Barr Virus-Associated Gastric Carcinoma

Search Clinical Trials , NIH Clinical Center for Epstein-Barr Virus-Associated Gastric Carcinoma

Genetic Tests for Epstein-Barr Virus-Associated Gastric Carcinoma

Anatomical Context for Epstein-Barr Virus-Associated Gastric Carcinoma

MalaCards organs/tissues related to Epstein-Barr Virus-Associated Gastric Carcinoma:

42
T Cells, Kidney, Colon, Lymph Node, Neutrophil

Publications for Epstein-Barr Virus-Associated Gastric Carcinoma

Articles related to Epstein-Barr Virus-Associated Gastric Carcinoma:

(show top 50) (show all 90)
# Title Authors Year
1
Viral loads correlate with upregulation of PD-L1 and worse patient prognosis in Epstein-Barr Virus-associated gastric carcinoma. ( 30695048 )
2019
2
Adenosine Induces EBV Lytic Reactivation through ADORA1 in EBV-Associated Gastric Carcinoma. ( 30875759 )
2019
3
An extremely rare case of Epstein-Barr virus-associated gastric carcinoma with differentiation to neuroendocrine carcinoma. ( 29244230 )
2018
4
The oncogenic role of Epstein-Barr virus-encoded microRNAs in Epstein-Barr virus-associated gastric carcinoma. ( 28990284 )
2018
5
CD47 expression in Epstein-Barr virus-associated gastric carcinoma: coexistence with tumor immunity lowering the ratio of CD8<sup>+</sup>/Foxp3<sup>+</sup> T cells. ( 29536167 )
2018
6
Knockdown of the lncRNA SNHG8 inhibits cell growth in Epstein-Barr virus-associated gastric carcinoma. ( 29736176 )
2018
7
Dihydroartemisinin suppresses the proliferation of Epstein-Barr virus-associated gastric carcinoma cells via downregulation of latent membrane protein 2A. ( 30013656 )
2018
8
The implication of tumor infiltrating lymphocytes in Epstein-Barr virus-associated gastric carcinoma. ( 30448221 )
2018
9
Determination and genome-wide analysis of Epstein-Barr virus (EBV) sequences in EBV-associated gastric carcinoma from Guangdong, an endemic area of nasopharyngeal carcinoma. ( 30239329 )
2018
10
Expression of CCL21 by EBV-associated gastric carcinoma cells protects CD8+CCR7+ T lymphocytes from apoptosis via the mitochondria-mediated pathway. ( 30149990 )
2018
11
MAP9 single nucleotide polymorphism rs1058992 is a risk of EBV-associated gastric carcinoma in Chinese population. ( 30472874 )
2018
12
DNA hypermethylation induced by Epstein-Barr virus in the development of Epstein-Barr virus-associated gastric carcinoma. ( 28779374 )
2017
13
The conundrum of the Epstein-Barr virus-associated gastric carcinoma in the Americas. ( 29088902 )
2017
14
Epstein-Barr Virus-Associated Gastric Carcinoma and Specific Features of the Accompanying Immune Response. ( 27104020 )
2016
15
Comprehensive profiling of virus microRNAs of Epstein-Barr virus-associated gastric carcinoma--- highlighting the interactions of ebv-Bart9 and host tumor cells. ( 27144885 )
2016
16
In Epstein-Barr virus-associated gastric carcinoma a high density of CD66b-positive tumor-associated neutrophils is associated with intestinal-type histology and low frequency of lymph node metastasis. ( 26915031 )
2016
17
Expression and prognostic roles of PIK3CA, JAK2, PD-L1, and PD-L2 in Epstein-Barr virus-associated gastric carcinoma. ( 26980034 )
2016
18
Association of single nucleotide polymorphism rs2065955 of the filaggrin gene with susceptibility to Epstein-Barr virus-associated gastric carcinoma and EBV-negative gastric carcinoma. ( 27535066 )
2016
19
Genome-wide analysis of Epstein-Barr virus (EBV) isolated from EBV-associated gastric carcinoma (EBVaGC). ( 26716899 )
2016
20
Epstein-Barr Virus-Associated Gastric Carcinoma: Use of Host Cell Machineries and Somatic Gene Mutations. ( 26337667 )
2015
21
Profiling of Virus-Encoded MicroRNAs in Epstein-Barr Virus-Associated Gastric Carcinoma and Their Roles in Gastric Carcinogenesis. ( 25740983 )
2015
22
Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation. ( 26427042 )
2015
23
Hypermethylation of the interferon regulatory factor 5 promoter in Epstein-Barr virus-associated gastric carcinoma. ( 25557482 )
2015
24
Accumulation Mechanisms of CD4(+)CD25(+)FOXP3(+) Regulatory T Cells in EBV-associated Gastric Carcinoma. ( 26673957 )
2015
25
Epigenetic dysregulation in Epstein-Barr virus-associated gastric carcinoma: disease and treatments. ( 24914366 )
2014
26
Subsequent Epstein-Barr virus-associated gastric carcinoma shortly after chemotherapy for colonic cancer. ( 23742899 )
2013
27
Role of DNA methylation in the development of Epstein-Barr virus-associated gastric carcinoma. ( 23073987 )
2013
28
Epigenetic silencing of WNT5A in Epstein-Barr virus-associated gastric carcinoma. ( 23001722 )
2013
29
Expression of c-myc and PCNA in Epstein-Barr virus-associated gastric carcinoma. ( 23599727 )
2013
30
Epstein-Barr virus-associated gastric carcinoma in Brazil: comparison between in situ hybridization and polymerase chain reaction detection. ( 24031845 )
2012
31
Epstein-Barr virus-associated gastric carcinoma: a newly defined entity. ( 22392024 )
2012
32
Treatment of Epstein-Barr virus-associated gastric carcinoma with endoscopic submucosal dissection. ( 22196795 )
2012
33
Epstein-Barr Virus (EBV)-associated gastric carcinoma. ( 23342366 )
2012
34
Epstein-Barr virus-associated gastric carcinoma 33 years after kidney transplantation. ( 25984103 )
2011
35
Epstein-Barr virus-associated gastric carcinoma. ( 21944426 )
2011
36
Epstein-Barr virus genome polymorphisms of Epstein-Barr virus-associated gastric carcinoma in gastric remnant carcinoma in Guangzhou, southern China, an endemic area of nasopharyngeal carcinoma. ( 21723347 )
2011
37
Pathology of epstein-barr virus-associated gastric carcinoma and its relationship to prognosis. ( 21814592 )
2011
38
Expression of Epstein-Barr Virus Gene and Clonality of Infiltrated T Lymphocytes in Epstein-Barr Virus-associated Gastric Carcinoma. ( 21494374 )
2011
39
Epstein-Barr virus-associated gastric carcinoma among patients with pernicious anemia. ( 21225628 )
2011
40
Frequent expression of thymidine phosphorylase in Epstein-Barr virus-associated gastric carcinoma of diffuse type. ( 20651404 )
2010
41
Correlation of Fas/FasL expression to cell apoptosis in Epstein-Barr virus-associated gastric carcinoma. ( 20193111 )
2010
42
Prominent Mott cell proliferation in Epstein-Barr virus-associated gastric carcinoma. ( 19665167 )
2010
43
Medical history and lifestyle factors contributing to Epstein-Barr virus-associated gastric carcinoma and conventional gastric carcinoma in Korea. ( 20651410 )
2010
44
Host inflammatory response predicts survival of patients with Epstein-Barr virus-associated gastric carcinoma. ( 20398662 )
2010
45
Collision of EBV-associated gastric carcinoma and primary gastric extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the remnant stomach. ( 20398194 )
2010
46
CT appearance of Epstein-Barr virus-associated gastric carcinoma. ( 18668190 )
2009
47
Epstein-Barr virus-associated gastric carcinoma: a distinct carcinoma of gastric phenotype by claudin expression profiling. ( 19398608 )
2009
48
Clinicopathological and molecular characteristics of Epstein-Barr virus-associated gastric carcinoma: a meta-analysis. ( 19335785 )
2009
49
EBV-associated gastric carcinoma in high- and low-incidence areas for nasopharyngeal carcinoma. ( 19603026 )
2009
50
Epstein-Barr virus associated gastric carcinoma: epidemiological and clinicopathological features. ( 18271915 )
2008

Variations for Epstein-Barr Virus-Associated Gastric Carcinoma

Expression for Epstein-Barr Virus-Associated Gastric Carcinoma

Search GEO for disease gene expression data for Epstein-Barr Virus-Associated Gastric Carcinoma.

Pathways for Epstein-Barr Virus-Associated Gastric Carcinoma

Pathways related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

(show all 42)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.81 CD274 CDH1 CTNNB1 FASLG IL10 IRF5
2
Show member pathways
13.69 CDH1 CTNNB1 FASLG JAK2 MUC2 MUC5AC
3
Show member pathways
13.33 FASLG IL10 IRF5 JAK2 PIK3CA PSMB9
4
Show member pathways
13.27 CDH1 CTNNB1 FAS FASLG IL10 JAK2
5
Show member pathways
13.15 FAS FASLG IL10 IRF5 PIK3CA TNF
6
Show member pathways
12.89 CDKN2A CTNNB1 FAS FASLG JAK2 PIK3CA
7
Show member pathways
12.86 CTNNB1 FAS FASLG JAK2 PIK3CA TNF
8
Show member pathways
12.68 CDH1 CDKN2A CTNNB1 MUC2 PIK3CA WNT5A
9
Show member pathways
12.65 CDKN2A FAS FASLG IRF5 PIK3CA TNF
10
Show member pathways
12.6 CDH1 CTNNB1 FAS FASLG PIK3CA TP73
11
Show member pathways
12.54 CTNNB1 IL10 JAK2 PIK3CA TNF
12
Show member pathways
12.53 FAS FASLG JAK2 PIK3CA TNF TP73
13 12.48 CDH1 CDKN2A CTNNB1 FAS FASLG JAK2
14 12.39 CDH1 CTNNB1 PSMB9 WNT5A
15
Show member pathways
12.39 MUC2 MUC5AC MUC6 PSMB9
16
Show member pathways
12.39 FAS IL10 PIK3CA TNF
17 12.3 CDKN2A CTNNB1 PIK3CA TNF WNT5A
18
Show member pathways
12.23 FAS FASLG PSMB9 TNF
19
Show member pathways
12.19 CD274 CTNNB1 PDCD1LG2 PIK3CA
20
Show member pathways
12.18 FAS FASLG JAK2 TNF
21
Show member pathways
12.16 FAS FASLG JAK2 TNF
22 12.15 CDH1 CTNNB1 TNF WNT5A
23 12.14 CTNNB1 IL10 TNF TP73
24
Show member pathways
12.13 CTNNB1 PIK3CA TNF WNT5A
25 12.11 CDH1 CTNNB1 TP73 WNT5A
26 12.05 CDH1 CTNNB1 PSMB9 WNT5A
27 12.04 CTNNB1 JAK2 PIK3CA WNT5A
28 12.04 CTNNB1 FAS FASLG PIK3CA TNF WNT5A
29 11.93 FASLG IL10 JAK2 TNF
30 11.79 IL10 MUC2 PIK3CA TNF
31 11.74 CD274 FAS FASLG IL10 IRF5 JAK2
32 11.71 CDH1 CTNNB1 PIK3CA
33 11.71 CDH1 IL10 TNF
34 11.63 IL10 JAK2 PIK3CA
35 11.62 CDKN2A FAS FASLG PIK3CA
36 11.49 CDKN2A CTNNB1 FASLG PIK3CA TP73 WNT5A
37 11.44 CDKN2A FAS FASLG TNF
38 11.43 FAS FASLG TNF
39 11.28 CDH1 CTNNB1 PIK3CA
40 11.19 FAS FASLG IL10 TNF
41 11.1 CDH1 CTNNB1 PIK3CA
42 10.8 CDH1 CTNNB1

GO Terms for Epstein-Barr Virus-Associated Gastric Carcinoma

Cellular components related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.97 CD274 CDH1 CTNNB1 FAS FASLG JAK2
2 membrane raft GO:0045121 9.62 FAS FASLG JAK2 TNF
3 flotillin complex GO:0016600 9.26 CDH1 CTNNB1
4 Golgi lumen GO:0005796 9.26 MUC2 MUC5AC MUC6 WNT5A
5 cell surface GO:0009986 9.17 CD274 CDH1 FAS FASLG PDCD1LG2 TNF
6 extracellular region GO:0005576 10.02 CDH1 FAS FASLG IL10 MUC5AC MUC6

Biological processes related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

(show all 34)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.99 CD274 FAS FASLG IL10 PDCD1LG2 TNF
2 positive regulation of transcription, DNA-templated GO:0045893 9.95 CDH1 CDKN2A CTNNB1 IL10 TNF TP73
3 regulation of gene expression GO:0010468 9.94 CTNNB1 IL10 PIK3CA TP73
4 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.83 PIK3CA TNF WNT5A
5 positive regulation of inflammatory response GO:0050729 9.82 JAK2 TNF WNT5A
6 regulation of inflammatory response GO:0050727 9.81 JAK2 TNF WNT5A
7 tumor necrosis factor-mediated signaling pathway GO:0033209 9.8 FASLG JAK2 TNF
8 positive regulation of DNA-binding transcription factor activity GO:0051091 9.8 CTNNB1 IL10 JAK2 TNF
9 cytokine-mediated signaling pathway GO:0019221 9.8 FASLG IL10 IRF5 JAK2 PIK3CA TNF
10 apoptotic signaling pathway GO:0097190 9.78 FAS FASLG TNF
11 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.77 MUC2 MUC5AC MUC6
12 cellular response to lipopolysaccharide GO:0071222 9.77 CD274 IL10 PDCD1LG2 TNF WNT5A
13 O-glycan processing GO:0016266 9.76 MUC2 MUC5AC MUC6
14 T cell costimulation GO:0031295 9.74 CD274 PDCD1LG2 PIK3CA
15 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.73 IL10 JAK2 TNF
16 response to organic substance GO:0010033 9.73 CDH1 IL10 TNF WNT5A
17 negative regulation of T cell proliferation GO:0042130 9.71 CD274 IL10 PDCD1LG2
18 maintenance of gastrointestinal epithelium GO:0030277 9.66 MUC2 MUC6
19 negative regulation of interleukin-10 production GO:0032693 9.66 CD274 PDCD1LG2
20 negative regulation of activated T cell proliferation GO:0046007 9.65 CD274 PDCD1LG2
21 negative regulation of interferon-gamma production GO:0032689 9.65 CD274 IL10 PDCD1LG2
22 midbrain dopaminergic neuron differentiation GO:1904948 9.64 CTNNB1 WNT5A
23 regulation of synapse organization GO:0050807 9.63 IL10 TNF WNT5A
24 endothelial cell apoptotic process GO:0072577 9.62 IL10 TNF
25 entry of bacterium into host cell GO:0035635 9.62 CDH1 CTNNB1
26 positive regulation of chemokine biosynthetic process GO:0045080 9.61 TNF WNT5A
27 negative regulation of cytokine secretion involved in immune response GO:0002740 9.58 IL10 TNF
28 extrinsic apoptotic signaling pathway GO:0097191 9.56 FAS FASLG JAK2 TNF
29 cellular response to indole-3-methanol GO:0071681 9.55 CDH1 CTNNB1
30 receptor biosynthetic process GO:0032800 9.52 IL10 TNF
31 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.35 CDKN2A FAS FASLG JAK2 TNF
32 necroptotic signaling pathway GO:0097527 9.33 FAS FASLG TNF
33 positive regulation of apoptotic process GO:0043065 9.23 CDKN2A CTNNB1 FAS FASLG IRF5 JAK2
34 positive regulation of transcription by RNA polymerase II GO:0045944 10.14 CDKN2A CTNNB1 IL10 IRF5 TNF TP73

Molecular functions related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.55 CD274 CDH1 CDKN2A CTNNB1 FAS FASLG
2 transcription regulatory region DNA binding GO:0044212 9.46 IRF5 TNF TP73 WNT5A
3 insulin receptor substrate binding GO:0043560 9.26 JAK2 PIK3CA
4 cytokine activity GO:0005125 9.26 FASLG IL10 TNF WNT5A

Sources for Epstein-Barr Virus-Associated Gastric Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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