MCID: EPS023
MIFTS: 42

Epstein-Barr Virus-Associated Gastric Carcinoma

Categories: Gastrointestinal diseases, Rare diseases, Cancer diseases

Aliases & Classifications for Epstein-Barr Virus-Associated Gastric Carcinoma

MalaCards integrated aliases for Epstein-Barr Virus-Associated Gastric Carcinoma:

Name: Epstein-Barr Virus-Associated Gastric Carcinoma 59
Ebv-Associated Gastric Carcinoma 59
Ebvagc 59

Characteristics:

Orphanet epidemiological data:

59
epstein-barr virus-associated gastric carcinoma
Inheritance: Multigenic/multifactorial;

Classifications:



External Ids:

Orphanet 59 ORPHA313920
ICD10 via Orphanet 34 C16.2 C16.0

Summaries for Epstein-Barr Virus-Associated Gastric Carcinoma

MalaCards based summary : Epstein-Barr Virus-Associated Gastric Carcinoma, also known as ebv-associated gastric carcinoma, is related to nasopharyngeal carcinoma and adult hepatocellular carcinoma. An important gene associated with Epstein-Barr Virus-Associated Gastric Carcinoma is SNHG8 (Small Nucleolar RNA Host Gene 8
To explore the functions of SNHG8, we identified its mRNA targets on the lncRNA-mRNA co-expression network of the Illumina Body Map, which contains the RNA sequencing data of mRNAs and lncRNAs from 16 normal human tissues. 
Dysfunction Pattern: Expression), and among its related pathways/superpathways are Innate Immune System and HIV Life Cycle. Affiliated tissues include neutrophil, t cells and kidney, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related Diseases for Epstein-Barr Virus-Associated Gastric Carcinoma

Diseases related to Epstein-Barr Virus-Associated Gastric Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)
# Related Disease Score Top Affiliating Genes
1 nasopharyngeal carcinoma 30.1 CDH1 CDKN2A CTNNB1 PIK3CA PSMB9
2 adult hepatocellular carcinoma 10.7 CTNNB1 PIK3CA
3 pancreatic intraductal papillary-mucinous neoplasm 10.7 MUC2 MUC6
4 prostate transitional cell carcinoma 10.7 CTNNB1 PIK3CA
5 punctate inner choroidopathy 10.6 IL10 TNF
6 tumor of exocrine pancreas 10.6 MUC2 MUC6
7 anaplastic thyroid cancer 10.6 CDH1 CTNNB1 PIK3CA
8 ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3 10.6 CTNNB1 PIK3CA TP73
9 tropical endomyocardial fibrosis 10.6 IL10 TNF
10 intestinal benign neoplasm 10.5 CDH1 CTNNB1 MUC2
11 tonsil cancer 10.5 CDKN2A TNF
12 pancreatic ductal carcinoma 10.5 CDKN2A MUC2 MUC6
13 cervical squamous cell carcinoma 10.5 CDH1 CDKN2A CTNNB1
14 colorectal adenocarcinoma 10.5 CDH1 CTNNB1 MUC2
15 listeriosis 10.4 CDH1 IL10 TNF
16 uterine carcinosarcoma 10.4 CDH1 CTNNB1 PIK3CA
17 bile duct carcinoma 10.4 CDH1 FASLG MUC2 PIK3CA
18 silicosis 10.4 FAS FASLG TNF
19 mesothelioma, malignant 10.4 CDH1 CDKN2A CTNNB1
20 pneumoconiosis 10.4 FAS FASLG TNF
21 lung squamous cell carcinoma 10.4 CD274 CDH1 CDKN2A PIK3CA
22 cholecystitis 10.4 CDH1 CDKN2A MUC2 MUC6
23 cell type benign neoplasm 10.4 CDKN2A CTNNB1 MUC2
24 signet ring cell adenocarcinoma 10.3 CDH1 CTNNB1 MUC2 MUC6
25 gastroenteritis 10.3 CDH1 IL10 TNF
26 type ii mixed cryoglobulinemia 10.3 FAS FASLG
27 female reproductive organ cancer 10.3 CDH1 CDKN2A CTNNB1 PIK3CA
28 microscopic polyangiitis 10.3 IL10 TNF
29 cap polyposis 10.3 MUC2 MUC5AC
30 acute graft versus host disease 10.3 FASLG IL10 TNF
31 viral hepatitis 10.3 FAS FASLG TNF
32 idiopathic neutropenia 10.3 FASLG IL10 TNF
33 multifocal choroiditis 10.3 IL10 TNF
34 helicobacter pylori infection 10.3 IL10 MUC6 TNF
35 gastrointestinal system benign neoplasm 10.3 CDH1 CDKN2A CTNNB1 MUC2
36 adamantinoma of long bones 10.2 CDH1 CDKN2A CTNNB1 PIK3CA
37 lymphadenitis 10.2 FASLG IL10 TNF
38 large intestine adenocarcinoma 10.2 CDH1 CTNNB1
39 orofacial granulomatosis 10.2 FLG IL10 TNF
40 mucinous intrahepatic cholangiocarcinoma 10.2 MUC2 MUC5AC MUC6
41 lynch syndrome 10.2 CD274 CDKN2A CTNNB1 MUC2
42 bile duct adenocarcinoma 10.2 CDH1 MUC2 MUC5AC
43 aging 10.2
44 chronic ethmoiditis 10.2 MUC2 MUC5AC MUC6
45 bile duct cystadenocarcinoma 10.2 MUC2 MUC5AC MUC6
46 biliary papillomatosis 10.2 MUC2 MUC5AC MUC6
47 ethmoid sinusitis 10.2 MUC2 MUC5AC MUC6
48 superior mesenteric artery syndrome 10.2 MUC2 MUC5AC MUC6
49 ovarian mucinous neoplasm 10.2 MUC2 MUC5AC MUC6
50 pseudomyxoma peritonei 10.2 MUC2 MUC5AC MUC6

Graphical network of the top 20 diseases related to Epstein-Barr Virus-Associated Gastric Carcinoma:



Diseases related to Epstein-Barr Virus-Associated Gastric Carcinoma

Symptoms & Phenotypes for Epstein-Barr Virus-Associated Gastric Carcinoma

GenomeRNAi Phenotypes related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.44 CDKN2A FAS IL10 PSMB9 TNF TP73
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.44 CDKN2A FAS FASLG IL10 PSMB9 TNF

MGI Mouse Phenotypes related to Epstein-Barr Virus-Associated Gastric Carcinoma:

46 (show all 17)
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 10.41 CD274 CDH1 CDKN2A CTNNB1 FAS FASLG
2 homeostasis/metabolism MP:0005376 10.4 CD274 CDH1 MUC2 MUC5AC PDCD1LG2 PIK3CA
3 cellular MP:0005384 10.37 CD274 CDH1 CDKN2A CTNNB1 FAS FASLG
4 hematopoietic system MP:0005397 10.36 CD274 CDKN2A CTNNB1 FAS FASLG IL10
5 endocrine/exocrine gland MP:0005379 10.34 WNT5A CDH1 CDKN2A CTNNB1 FAS FASLG
6 cardiovascular system MP:0005385 10.31 CDH1 CDKN2A CTNNB1 FAS FASLG IL10
7 digestive/alimentary MP:0005381 10.29 CDH1 CDKN2A CTNNB1 FAS FASLG IL10
8 mortality/aging MP:0010768 10.25 MUC2 PDCD1LG2 PIK3CA TNF TP73 WNT5A
9 embryo MP:0005380 10.19 CDH1 CDKN2A CTNNB1 IL10 JAK2 PIK3CA
10 neoplasm MP:0002006 10.18 CDH1 CDKN2A CTNNB1 FAS FASLG IL10
11 integument MP:0010771 10.16 CDH1 CDKN2A CTNNB1 FAS FASLG IL10
12 liver/biliary system MP:0005370 10.03 JAK2 TNF WNT5A CDKN2A CTNNB1 FAS
13 reproductive system MP:0005389 10 PIK3CA TNF TP73 WNT5A CDH1 CDKN2A
14 no phenotypic analysis MP:0003012 9.92 PDCD1LG2 PIK3CA TNF CD274 CDH1 CDKN2A
15 respiratory system MP:0005388 9.76 CDKN2A CTNNB1 FAS FASLG IL10 TNF
16 skeleton MP:0005390 9.7 CD274 CDKN2A CTNNB1 FAS FASLG IL10
17 vision/eye MP:0005391 9.28 CDKN2A CTNNB1 FAS FASLG IL10 MUC5AC

Drugs & Therapeutics for Epstein-Barr Virus-Associated Gastric Carcinoma

Search Clinical Trials , NIH Clinical Center for Epstein-Barr Virus-Associated Gastric Carcinoma

Genetic Tests for Epstein-Barr Virus-Associated Gastric Carcinoma

Anatomical Context for Epstein-Barr Virus-Associated Gastric Carcinoma

MalaCards organs/tissues related to Epstein-Barr Virus-Associated Gastric Carcinoma:

41
Neutrophil, T Cells, Kidney, Colon, Lymph Node

Publications for Epstein-Barr Virus-Associated Gastric Carcinoma

Articles related to Epstein-Barr Virus-Associated Gastric Carcinoma:

(show top 50) (show all 83)
# Title Authors Year
1
An extremely rare case of Epstein-Barr virus-associated gastric carcinoma with differentiation to neuroendocrine carcinoma. ( 29244230 )
2018
2
The oncogenic role of Epstein-Barr virus-encoded microRNAs in Epstein-Barr virus-associated gastric carcinoma. ( 28990284 )
2018
3
CD47 expression in Epstein-Barr virus-associated gastric carcinoma: coexistence with tumor immunity lowering the ratio of CD8<sup>+</sup>/Foxp3<sup>+</sup> T cells. ( 29536167 )
2018
4
Knockdown of the lncRNA SNHG8 inhibits cell growth in Epstein-Barr virus-associated gastric carcinoma. ( 29736176 )
2018
5
DNA hypermethylation induced by Epstein-Barr virus in the development of Epstein-Barr virus-associated gastric carcinoma. ( 28779374 )
2017
6
The conundrum of the Epstein-Barr virus-associated gastric carcinoma in the Americas. ( 29088902 )
2017
7
Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas. ( 28493890 )
2017
8
Epstein-Barr Virus-Associated Gastric Carcinoma and Specific Features of the Accompanying Immune Response. ( 27104020 )
2016
9
Comprehensive profiling of virus microRNAs of Epstein-Barr virus-associated gastric carcinoma--- highlighting the interactions of ebv-Bart9 and host tumor cells. ( 27144885 )
2016
10
In Epstein-Barr virus-associated gastric carcinoma a high density of CD66b-positive tumor-associated neutrophils is associated with intestinal-type histology and low frequency of lymph node metastasis. ( 26915031 )
2016
11
Expression and prognostic roles of PIK3CA, JAK2, PD-L1, and PD-L2 in Epstein-Barr virus-associated gastric carcinoma. ( 26980034 )
2016
12
Association of single nucleotide polymorphism rs2065955 of the filaggrin gene with susceptibility to Epstein-Barr virus-associated gastric carcinoma and EBV-negative gastric carcinoma. ( 27535066 )
2016
13
Epstein-Barr Virus-Associated Gastric Carcinoma: Use of Host Cell Machineries and Somatic Gene Mutations. ( 26337667 )
2015
14
Aberrant gene promoter methylation of p16, FHIT, CRBP1, WWOX, and DLC-1 in Epstein-Barr virus-associated gastric carcinomas. ( 25720522 )
2015
15
Profiling of Virus-Encoded MicroRNAs in Epstein-Barr Virus-Associated Gastric Carcinoma and Their Roles in Gastric Carcinogenesis. ( 25740983 )
2015
16
Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation. ( 26427042 )
2015
17
Hypermethylation of the interferon regulatory factor 5 promoter in Epstein-Barr virus-associated gastric carcinoma. ( 25557482 )
2015
18
Epstein-Barr virus latent membrane protein 2A suppresses the expression of HER2 via a pathway involving TWIST and YB-1 in Epstein-Barr virus-associated gastric carcinomas. ( 25402957 )
2015
19
Epigenetic dysregulation in Epstein-Barr virus-associated gastric carcinoma: disease and treatments. ( 24914366 )
2014
20
Subsequent Epstein-Barr virus-associated gastric carcinoma shortly after chemotherapy for colonic cancer. ( 23742899 )
2013
21
Role of DNA methylation in the development of Epstein-Barr virus-associated gastric carcinoma. ( 23073987 )
2013
22
Epigenetic silencing of WNT5A in Epstein-Barr virus-associated gastric carcinoma. ( 23001722 )
2013
23
Expression of c-myc and PCNA in Epstein-Barr virus-associated gastric carcinoma. ( 23599727 )
2013
24
Identification of genes specifically methylated in Epstein-Barr virus-associated gastric carcinomas. ( 23829175 )
2013
25
Sequence variations of latent membrane protein 2A in Epstein-Barr virus-associated gastric carcinomas from Guangzhou, southern China. ( 22470549 )
2012
26
Epstein-Barr virus-associated gastric carcinoma in Brazil: comparison between in situ hybridization and polymerase chain reaction detection. ( 24031845 )
2012
27
Epstein-Barr virus-associated gastric carcinoma: a newly defined entity. ( 22392024 )
2012
28
Treatment of Epstein-Barr virus-associated gastric carcinoma with endoscopic submucosal dissection. ( 22196795 )
2012
29
Epstein-Barr virus-associated gastric carcinoma 33 years after kidney transplantation. ( 25984103 )
2011
30
Epstein-Barr virus-associated gastric carcinoma. ( 21944426 )
2011
31
Epstein-Barr virus genome polymorphisms of Epstein-Barr virus-associated gastric carcinoma in gastric remnant carcinoma in Guangzhou, southern China, an endemic area of nasopharyngeal carcinoma. ( 21723347 )
2011
32
Pathology of epstein-barr virus-associated gastric carcinoma and its relationship to prognosis. ( 21814592 )
2011
33
Expression of Epstein-Barr Virus Gene and Clonality of Infiltrated T Lymphocytes in Epstein-Barr Virus-associated Gastric Carcinoma. ( 21494374 )
2011
34
Epstein-Barr virus-associated gastric carcinoma among patients with pernicious anemia. ( 21225628 )
2011
35
Frequent expression of thymidine phosphorylase in Epstein-Barr virus-associated gastric carcinoma of diffuse type. ( 20651404 )
2010
36
Correlation of Fas/FasL expression to cell apoptosis in Epstein-Barr virus-associated gastric carcinoma. ( 20193111 )
2010
37
Prominent Mott cell proliferation in Epstein-Barr virus-associated gastric carcinoma. ( 19665167 )
2010
38
Medical history and lifestyle factors contributing to Epstein-Barr virus-associated gastric carcinoma and conventional gastric carcinoma in Korea. ( 20651410 )
2010
39
Host inflammatory response predicts survival of patients with Epstein-Barr virus-associated gastric carcinoma. ( 20398662 )
2010
40
CT appearance of Epstein-Barr virus-associated gastric carcinoma. ( 18668190 )
2009
41
Epstein-Barr virus-associated gastric carcinoma: a distinct carcinoma of gastric phenotype by claudin expression profiling. ( 19398608 )
2009
42
Clinicopathological and molecular characteristics of Epstein-Barr virus-associated gastric carcinoma: a meta-analysis. ( 19335785 )
2009
43
Epstein-Barr virus associated gastric carcinoma: epidemiological and clinicopathological features. ( 18271915 )
2008
44
E-cadherin and beta-catenin expression in Epstein-Barr virus-associated gastric carcinoma and their prognostic significance. ( 17663505 )
2007
45
Epstein-Barr virus associated gastric carcinoma: a report from Iran in the last four decades. ( 17629938 )
2007
46
p73 gene promoter methylation in Epstein-Barr virus-associated gastric carcinoma. ( 17058198 )
2007
47
Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma. ( 17079300 )
2007
48
Coexistence of Epstein-Barr virus-associated gastric carcinoma with malignant lymphoma: report of two cases. ( 16609909 )
2006
49
Phenotype analysis by MUC2, MUC5AC, MUC6, and CD10 expression in Epstein-Barr virus-associated gastric carcinoma. ( 16988760 )
2006
50
Mucin and differentiation in Epstein-Barr virus-associated gastric carcinoma. ( 16001631 )
2005

Variations for Epstein-Barr Virus-Associated Gastric Carcinoma

Expression for Epstein-Barr Virus-Associated Gastric Carcinoma

Search GEO for disease gene expression data for Epstein-Barr Virus-Associated Gastric Carcinoma.

Pathways for Epstein-Barr Virus-Associated Gastric Carcinoma

Pathways related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

(show all 41)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.84 CD274 CDH1 CTNNB1 FASLG IL10 IRF5
2
Show member pathways
13.69 CDH1 CTNNB1 FASLG JAK2 MUC2 MUC5AC
3
Show member pathways
13.33 FASLG IL10 IRF5 JAK2 PIK3CA PSMB9
4
Show member pathways
13.27 CDH1 CTNNB1 FAS FASLG IL10 JAK2
5
Show member pathways
12.98 FAS FASLG IL10 IRF5 PIK3CA TNF
6
Show member pathways
12.87 CTNNB1 FAS FASLG JAK2 PIK3CA TNF
7
Show member pathways
12.73 FAS FASLG JAK2 PIK3CA TNF TP73
8
Show member pathways
12.69 CDH1 CDKN2A CTNNB1 MUC2 PIK3CA WNT5A
9
Show member pathways
12.62 CDH1 CTNNB1 FAS FASLG PIK3CA TP73
10
Show member pathways
12.61 CDKN2A FAS FASLG IRF5 PIK3CA TNF
11
Show member pathways
12.58 IL10 IRF5 JAK2 PIK3CA TNF
12
Show member pathways
12.55 CTNNB1 IL10 JAK2 PIK3CA TNF
13 12.48 CDH1 CDKN2A CTNNB1 FAS FASLG JAK2
14
Show member pathways
12.45 CTNNB1 FAS FASLG JAK2 PIK3CA TNF
15
Show member pathways
12.39 MUC2 MUC5AC MUC6 PSMB9
16
Show member pathways
12.39 FAS IL10 PIK3CA TNF
17 12.36 CDKN2A CTNNB1 PIK3CA TNF WNT5A
18
Show member pathways
12.19 CD274 CTNNB1 PDCD1LG2 PIK3CA
19
Show member pathways
12.19 FAS FASLG JAK2 TNF
20
Show member pathways
12.16 FAS FASLG JAK2 TNF
21 12.16 CDH1 CTNNB1 TNF WNT5A
22 12.15 CTNNB1 IL10 TNF TP73
23
Show member pathways
12.13 CTNNB1 PIK3CA TNF WNT5A
24 12.11 CDH1 CTNNB1 TP73 WNT5A
25 12.06 CDH1 CTNNB1 PSMB9 WNT5A
26 12.04 CTNNB1 JAK2 PIK3CA WNT5A
27 12.04 CTNNB1 FAS FASLG PIK3CA TNF WNT5A
28 11.93 FASLG IL10 JAK2 TNF
29 11.81 IL10 MUC2 PIK3CA TNF
30 11.74 CD274 FAS FASLG IL10 IRF5 JAK2
31 11.71 CDH1 CTNNB1 PIK3CA
32 11.71 CDH1 IL10 TNF
33 11.64 CDKN2A FAS FASLG PIK3CA
34 11.63 IL10 JAK2 PIK3CA
35 11.49 CDKN2A CTNNB1 FASLG PIK3CA TP73 WNT5A
36 11.44 CDKN2A FAS FASLG TNF
37 11.43 FAS FASLG TNF
38 11.28 CDH1 CTNNB1 PIK3CA
39 11.17 FAS FASLG IL10 TNF
40 11.11 CDH1 CTNNB1 PIK3CA
41 10.8 CDH1 CTNNB1

GO Terms for Epstein-Barr Virus-Associated Gastric Carcinoma

Cellular components related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.97 CD274 CDH1 CTNNB1 FAS FASLG JAK2
2 membrane raft GO:0045121 9.62 FAS FASLG JAK2 TNF
3 flotillin complex GO:0016600 9.26 CDH1 CTNNB1
4 Golgi lumen GO:0005796 9.26 MUC2 MUC5AC MUC6 WNT5A
5 cell surface GO:0009986 9.17 CD274 CDH1 FAS FASLG PDCD1LG2 TNF
6 extracellular region GO:0005576 10.02 CDH1 FAS FASLG IL10 MUC5AC MUC6

Biological processes related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

(show all 36)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.99 CD274 FAS FASLG IL10 PDCD1LG2 TNF
2 regulation of cell proliferation GO:0042127 9.96 CTNNB1 FAS JAK2 TNF
3 regulation of gene expression GO:0010468 9.93 CTNNB1 IL10 PIK3CA TP73
4 response to lipopolysaccharide GO:0032496 9.9 FAS FASLG IL10 JAK2
5 cytokine-mediated signaling pathway GO:0019221 9.88 FASLG IL10 IRF5 JAK2 PIK3CA TNF
6 regulation of inflammatory response GO:0050727 9.84 JAK2 TNF WNT5A
7 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.84 MUC2 MUC5AC MUC6 PSMB9
8 positive regulation of DNA binding transcription factor activity GO:0051091 9.83 CTNNB1 IL10 JAK2 TNF
9 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.82 PIK3CA TNF WNT5A
10 apoptotic signaling pathway GO:0097190 9.82 FAS FASLG TNF
11 T cell costimulation GO:0031295 9.8 CD274 PDCD1LG2 PIK3CA
12 O-glycan processing GO:0016266 9.78 MUC2 MUC5AC MUC6
13 response to organic substance GO:0010033 9.78 CDH1 IL10 TNF WNT5A
14 cellular response to lipopolysaccharide GO:0071222 9.77 CD274 IL10 PDCD1LG2 TNF WNT5A
15 negative regulation of T cell proliferation GO:0042130 9.74 CD274 IL10 PDCD1LG2
16 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.73 IL10 JAK2 TNF
17 tumor necrosis factor-mediated signaling pathway GO:0033209 9.72 FAS FASLG JAK2 PSMB9 TNF
18 negative regulation of interleukin-10 production GO:0032693 9.67 CD274 PDCD1LG2
19 negative regulation of interferon-gamma production GO:0032689 9.67 CD274 IL10 PDCD1LG2
20 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.66 IL10 TNF
21 maintenance of gastrointestinal epithelium GO:0030277 9.65 MUC2 MUC6
22 entry of bacterium into host cell GO:0035635 9.65 CDH1 CTNNB1
23 negative regulation of activated T cell proliferation GO:0046007 9.64 CD274 PDCD1LG2
24 midbrain dopaminergic neuron differentiation GO:1904948 9.62 CTNNB1 WNT5A
25 positive regulation of chemokine biosynthetic process GO:0045080 9.62 TNF WNT5A
26 endothelial cell apoptotic process GO:0072577 9.61 IL10 TNF
27 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 9.61 FAS FASLG JAK2
28 negative regulation of cytokine secretion involved in immune response GO:0002740 9.58 IL10 TNF
29 cellular response to indole-3-methanol GO:0071681 9.58 CDH1 CTNNB1
30 extrinsic apoptotic signaling pathway GO:0097191 9.56 FAS FASLG JAK2 TNF
31 receptor biosynthetic process GO:0032800 9.55 IL10 TNF
32 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.35 CDKN2A FAS FASLG JAK2 TNF
33 necroptotic signaling pathway GO:0097527 9.33 FAS FASLG TNF
34 positive regulation of apoptotic process GO:0043065 9.23 CDKN2A CTNNB1 FAS FASLG IRF5 JAK2
35 positive regulation of transcription by RNA polymerase II GO:0045944 10.14 CDKN2A CTNNB1 IL10 IRF5 TNF TP73
36 positive regulation of transcription, DNA-templated GO:0045893 10 CDH1 CDKN2A CTNNB1 IL10 TNF TP73

Molecular functions related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.58 CD274 CDH1 CDKN2A CTNNB1 FAS FASLG
2 transcription regulatory region DNA binding GO:0044212 9.56 IRF5 TNF TP73 WNT5A
3 cytokine activity GO:0005125 9.26 FASLG IL10 TNF WNT5A
4 insulin receptor substrate binding GO:0043560 9.16 JAK2 PIK3CA

Sources for Epstein-Barr Virus-Associated Gastric Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....