MCID: EPS023
MIFTS: 27

Epstein-Barr Virus-Associated Gastric Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Epstein-Barr Virus-Associated Gastric Carcinoma

MalaCards integrated aliases for Epstein-Barr Virus-Associated Gastric Carcinoma:

Name: Epstein-Barr Virus-Associated Gastric Carcinoma 58
Ebv-Associated Gastric Carcinoma 58
Ebvagc 58

Characteristics:

Orphanet epidemiological data:

58
epstein-barr virus-associated gastric carcinoma
Inheritance: Multigenic/multifactorial;

Classifications:

Orphanet: 58  
Rare gastroenterological diseases


External Ids:

ICD10 via Orphanet 33 C16.0 C16.2
Orphanet 58 ORPHA313920

Summaries for Epstein-Barr Virus-Associated Gastric Carcinoma

MalaCards based summary : Epstein-Barr Virus-Associated Gastric Carcinoma, also known as ebv-associated gastric carcinoma, is related to lymphoepithelioma-like carcinoma and oral cancer. An important gene associated with Epstein-Barr Virus-Associated Gastric Carcinoma is SNHG8 (Small Nucleolar RNA Host Gene 8), and among its related pathways/superpathways are Dendritic Cells Developmental Lineage Pathway and Bladder cancer. Affiliated tissues include colon, lung and skin, and related phenotype is no phenotypic analysis.

Related Diseases for Epstein-Barr Virus-Associated Gastric Carcinoma

Diseases related to Epstein-Barr Virus-Associated Gastric Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 125)
# Related Disease Score Top Affiliating Genes
1 lymphoepithelioma-like carcinoma 31.1 CDH1 CD274
2 oral cancer 30.3 CDKN2A CDH1
3 diffuse large b-cell lymphoma 29.9 TNF CDKN2A CD274
4 esophageal cancer 29.5 TNF CDKN2A CDH1 CD274
5 gastritis 10.6
6 nasopharyngeal carcinoma 10.5
7 gastric adenocarcinoma 10.5
8 helicobacter pylori infection 10.4
9 gastric cancer 10.3
10 tubular adenocarcinoma 10.3
11 severe combined immunodeficiency 10.3
12 atrophic gastritis 10.3
13 epstein-barr virus-associated carcinoma 10.3
14 pfeiffer syndrome 10.2
15 burkitt lymphoma 10.2
16 pernicious anemia 10.2
17 ataxia-telangiectasia 10.2
18 ataxia and polyneuropathy, adult-onset 10.2
19 deficiency anemia 10.2
20 follicular lymphoma 10.2
21 combined immunodeficiency 10.2
22 gastric lymphoma 10.2
23 gastric ulcer 10.2
24 telangiectasis 10.2
25 neuroendocrine carcinoma 10.2
26 vaccinia 10.2
27 b-cell lymphoma 10.2
28 crohn's disease 10.2
29 rare tumor 10.2
30 primary cutaneous diffuse large b-cell lymphoma, leg type 10.1 CDKN2A CD274
31 bladder squamous cell carcinoma 10.1 CDKN2A CD274
32 vulva squamous cell carcinoma 10.1 CDKN2A CD274
33 malignant spindle cell melanoma 10.1 CDKN2A CD274
34 vulvar disease 10.1 CDKN2A CD274
35 anus cancer 10.1 CDKN2A CD274
36 acral lentiginous melanoma 10.1 CDKN2A CD274
37 follicular dendritic cell sarcoma 10.1 CDKN2A CD274
38 mucosal melanoma 10.1 CDKN2A CD274
39 carcinosarcoma 10.1 CDKN2A CDH1
40 peritoneal mesothelioma 10.1 CDKN2A CD274
41 vulvar intraepithelial neoplasia 10.1 CDKN2A CDH1
42 vulva cancer 10.1 CDKN2A CD274
43 esophagus verrucous carcinoma 10.1 CDKN2A CDH1
44 maxillary sinus benign neoplasm 10.1 CDKN2A CDH1
45 keratinizing squamous cell carcinoma 10.1 CDKN2A CDH1
46 pleural cancer 10.1 CDKN2A CD274
47 central nervous system lymphoma 10.1 CDKN2A CD274
48 borst-jadassohn intraepidermal carcinoma 10.1 CDKN2A CDH1
49 hypopharynx cancer 10.1 CDKN2A CDH1
50 penile cancer 10.1 CDKN2A CD274

Graphical network of the top 20 diseases related to Epstein-Barr Virus-Associated Gastric Carcinoma:



Diseases related to Epstein-Barr Virus-Associated Gastric Carcinoma

Symptoms & Phenotypes for Epstein-Barr Virus-Associated Gastric Carcinoma

MGI Mouse Phenotypes related to Epstein-Barr Virus-Associated Gastric Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 8.92 CD274 CDH1 CDKN2A TNF

Drugs & Therapeutics for Epstein-Barr Virus-Associated Gastric Carcinoma

Search Clinical Trials , NIH Clinical Center for Epstein-Barr Virus-Associated Gastric Carcinoma

Genetic Tests for Epstein-Barr Virus-Associated Gastric Carcinoma

Anatomical Context for Epstein-Barr Virus-Associated Gastric Carcinoma

MalaCards organs/tissues related to Epstein-Barr Virus-Associated Gastric Carcinoma:

40
Colon, Lung, Skin, Ovary, Lymph Node, T Cells, Eye

Publications for Epstein-Barr Virus-Associated Gastric Carcinoma

Articles related to Epstein-Barr Virus-Associated Gastric Carcinoma:

(show top 50) (show all 225)
# Title Authors PMID Year
1
Identification of anti-Epstein-Barr virus (EBV) antibody signature in EBV-associated gastric carcinoma. 61
33661412 2021
2
Expression of MAP9 in Epstein-Barr virus-associated gastric carcinoma. 61
33309912 2021
3
Exosomes of Epstein-Barr Virus-Associated Gastric Carcinoma Suppress Dendritic Cell Maturation. 61
33198173 2020
4
EBV-miR-BART10-3p and EBV-miR-BART22 promote metastasis of EBV-associated gastric carcinoma by activating the canonical Wnt signaling pathway. 61
32533512 2020
5
Risk for lymph node metastasis in Epstein-Barr virus-associated gastric carcinoma with submucosal invasion. 61
32852875 2020
6
Epstein-Barr virus-associated gastric carcinomas developed after successful eradication of Helicobacter pylori. 61
31970662 2020
7
Cancer stem cells in Epstein-Barr virus-associated gastric carcinoma. 61
32338409 2020
8
CD44+CD24-/low sphere-forming cells of EBV-associated gastric carcinomas show immunosuppressive effects and induce Tregs partially through production of PGE2. 61
32197932 2020
9
Epstein-Barr virus-associated gastric carcinoma with heterogeneous EBER positivity accompanied by distinctive morphological cellular changes. 61
32173925 2020
10
Positive Status of Epstein-Barr Virus as a Biomarker for Gastric Cancer Immunotherapy: A Prospective Observational Study. 61
32134806 2020
11
Bilateral Breast Metastases from Epstein-Barr Virus-Associated Gastric Cancer during Pregnancy: Is There a Method to Its Madness? 61
32269849 2020
12
Prevalence and characteristics of Epstein-Barr virus associated gastric carcinoma in Gansu Province, Northwest China with mRNA expression of glycoprotein BMRF2. 61
31663617 2020
13
Thirty years of Epstein-Barr virus-associated gastric carcinoma. 61
31836926 2020
14
Dysregulation of FOXO transcription factors in Epstein-Barr virus-associated gastric carcinoma. 61
31712122 2020
15
Prospective observation: Clinical utility of plasma Epstein-Barr virus DNA load in EBV-associated gastric carcinoma patients. 61
31162842 2020
16
CXCR4 induces cell autophagy and maintains EBV latent infection in EBVaGC. 61
33052232 2020
17
A novel vaccine candidate based on chimeric virus-like particle displaying multiple conserved epitope peptides induced neutralizing antibodies against EBV infection. 61
32483413 2020
18
Establishment of a Screening Method for Epstein-Barr Virus-Associated Gastric Carcinoma by Droplet Digital PCR. 61
31795435 2019
19
Quercetin Synergistically Inhibit EBV-Associated Gastric Carcinoma with Ganoderma lucidum Extracts. 61
31653035 2019
20
Comprehensive Multi-Omics Analysis Reveals Aberrant Metabolism of Epstein-Barr-Virus-Associated Gastric Carcinoma. 61
31597357 2019
21
Lentivirus-mediated RNA interference targeting EBNA1 gene inhibits the growth of GT-38 cells in vitro and in vivo. 61
31402935 2019
22
Clinicopathologic Characteristics of Epstein-Barr Virus-Associated Gastric Cancer Over the Past Decade in Japan. 61
31480554 2019
23
LMP2A induces DNA methylation and expression repression of AQP3 in EBV-associated gastric carcinoma. 61
31220652 2019
24
A case of multifocal EBV associated gastric carcinoma with focal squamous differentiation. 61
31361258 2019
25
Constitutive activation of the canonical NF-κB signaling pathway in EBV-associated gastric carcinoma. 61
30974373 2019
26
Clinicopathological features of Epstein-Barr virus-associated gastric carcinoma: A systematic review and meta-analysis. 61
31424666 2019
27
Adenosine Induces EBV Lytic Reactivation through ADORA1 in EBV-Associated Gastric Carcinoma. 61
30875759 2019
28
The implication of tumor-infiltrating lymphocytes in Epstein-Barr virus-associated gastric carcinoma. 61
30448221 2019
29
Distribution of the Epstein-Barr virus in the normal stomach and gastric lesions in Thai population. 61
30229949 2019
30
Viral loads correlate with upregulation of PD-L1 and worse patient prognosis in Epstein-Barr Virus-associated gastric carcinoma. 61
30695048 2019
31
EBV miR-BART10-3p Promotes Cell Proliferation and Migration by Targeting DKK1. 61
30745852 2019
32
The Glypican-4 Gene Polymorphism rs1048369 and Susceptibility to Epstein-Barr Virus-Positive and -Negative Nasopharyngeal Carcinoma in Northern China. 61
31522169 2019
33
Epstein-Barr Virus MicroRNA miR-BART5-3p Inhibits p53 Expression. 61
30209170 2018
34
Determination and genome-wide analysis of Epstein-Barr virus (EBV) sequences in EBV-associated gastric carcinoma from Guangdong, an endemic area of nasopharyngeal carcinoma. 61
30239329 2018
35
Expression of CCL21 by EBV-associated gastric carcinoma cells protects CD8+CCR7+ T lymphocytes from apoptosis via the mitochondria-mediated pathway. 61
30149990 2018
36
EBV Positive Gastric Carcinomas and Their Clinicopathological Characteristics. 61
30455757 2018
37
Epstein-Barr virus miRNA-BART16 modulates cell proliferation by targeting LMP1. 61
30077726 2018
38
Dihydroartemisinin suppresses the proliferation of Epstein-Barr virus-associated gastric carcinoma cells via downregulation of latent membrane protein 2A. 61
30013656 2018
39
MAPK/c-Jun signaling pathway contributes to the upregulation of the anti-apoptotic proteins Bcl-2 and Bcl-xL induced by Epstein-Barr virus-encoded BARF1 in gastric carcinoma cells. 61
29725459 2018
40
Clinical Importance of Epstein⁻Barr Virus-Associated Gastric Cancer. 61
29843478 2018
41
CD47 expression in Epstein-Barr virus-associated gastric carcinoma: coexistence with tumor immunity lowering the ratio of CD8+/Foxp3+ T cells. 61
29536167 2018
42
MAP9 single nucleotide polymorphism rs1058992 is a risk of EBV-associated gastric carcinoma in Chinese population. 61
30472874 2018
43
Knockdown of the lncRNA SNHG8 inhibits cell growth in Epstein-Barr virus-associated gastric carcinoma. 61
29736176 2018
44
An extremely rare case of Epstein-Barr virus-associated gastric carcinoma with differentiation to neuroendocrine carcinoma. 61
29244230 2018
45
Immunization With Fc-Based Recombinant Epstein-Barr Virus gp350 Elicits Potent Neutralizing Humoral Immune Response in a BALB/c Mice Model. 61
29765376 2018
46
The oncogenic role of Epstein-Barr virus-encoded microRNAs in Epstein-Barr virus-associated gastric carcinoma. 61
28990284 2018
47
Genome-wide analysis of Epstein-Barr virus identifies variants and genes associated with gastric carcinoma and population structure. 61
29034771 2017
48
Transforming Growth Factor-β, Interleukin-10, and Serological Markers in EBV-associated Gastric Carcinoma. 61
28870905 2017
49
The conundrum of the Epstein-Barr virus-associated gastric carcinoma in the Americas. 61
29088902 2017
50
P53 deregulation in Epstein-Barr virus-associated gastric cancer. 61
28729047 2017

Variations for Epstein-Barr Virus-Associated Gastric Carcinoma

Expression for Epstein-Barr Virus-Associated Gastric Carcinoma

Search GEO for disease gene expression data for Epstein-Barr Virus-Associated Gastric Carcinoma.

Pathways for Epstein-Barr Virus-Associated Gastric Carcinoma

Pathways related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.13 TNF CDH1
2 11.02 CDKN2A CDH1
3 10.78 TNF CD274
4 10.33 TNF CDKN2A

GO Terms for Epstein-Barr Virus-Associated Gastric Carcinoma

Biological processes related to Epstein-Barr Virus-Associated Gastric Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 8.96 TNF CDKN2A
2 response to organic substance GO:0010033 8.62 TNF CDH1

Sources for Epstein-Barr Virus-Associated Gastric Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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