MCID: EPL003
MIFTS: 35

Epulis

Categories: Cancer diseases, Oral diseases, Rare diseases

Aliases & Classifications for Epulis

MalaCards integrated aliases for Epulis:

Name: Epulis 12 15
Epulides 12 74
Gingival Polyp 12
Polyp of Gum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5337
MeSH 45 D005882
NCIt 51 C3948
SNOMED-CT 69 45676007 71708001
UMLS 74 C0266919

Summaries for Epulis

MalaCards based summary : Epulis, also known as epulides, is related to congenital epulis and giant cell tumor. An important gene associated with Epulis is DES (Desmin), and among its related pathways/superpathways are Striated Muscle Contraction and Aurora B signaling. Affiliated tissues include breast, tongue and ovary.

Wikipedia : 77 Epulis (Greek: ἐπουλίς; plural epulides) is any tumor like enlargement (i.e. lump) situated on the... more...

Related Diseases for Epulis

Diseases in the Epulis family:

Congenital Epulis

Diseases related to Epulis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 131)
# Related Disease Score Top Affiliating Genes
1 congenital epulis 33.0 DES ENO2 NGFR PGR VIM
2 giant cell tumor 30.3 DES SERPINA3 VIM
3 granular cell tumor 30.1 DES ENO2 SERPINA3 VIM
4 melanotic neuroectodermal tumor 30.0 ENO2 VIM
5 leiomyosarcoma 29.4 DES ENO2 PGR VIM
6 gingival overgrowth 11.1
7 fibroma 10.3
8 infantile digital fibromatosis 10.3 DES VIM
9 fibromatosis 10.3 DES VIM
10 angiolipoma 10.3 DES VIM
11 spindle cell lipoma 10.2 DES VIM
12 parachordoma 10.2 DES VIM
13 chordoma 10.2 DES VIM
14 adenosarcoma 10.2 DES PGR
15 syringocystadenoma papilliferum 10.2 DES VIM
16 biphasic synovial sarcoma 10.2 DES VIM
17 syringoma 10.2 DES VIM
18 juvenile xanthogranuloma 10.2 DES VIM
19 pleomorphic liposarcoma 10.2 DES VIM
20 liposarcoma 10.2 DES VIM
21 benign breast phyllodes tumor 10.2 PGR VIM
22 congenital fibrosarcoma 10.2 DES VIM
23 reticulum cell sarcoma 10.2 DES VIM
24 endometrial mucinous adenocarcinoma 10.2 PGR VIM
25 clear cell meningioma 10.2 PGR VIM
26 mesenchymal chondrosarcoma 10.2 DES VIM
27 pseudosarcomatous fibromatosis 10.2 DES VIM
28 spindle cell sarcoma 10.2 DES VIM
29 noma 10.2 NGFR PGR
30 sertoli cell tumor 10.2 PGR VIM
31 dermoid cyst 10.2 PGR VIM
32 infantile myofibromatosis 10.2 DES VIM
33 intravascular papillary endothelial hyperplasia 10.2 SERPINA3 VIM
34 dupuytren contracture 10.2 DES NGFR
35 malignant ectomesenchymoma 10.2 DES ENO2
36 angiomyolipoma 10.2 DES PGR
37 ectomesenchymoma 10.2 DES ENO2
38 chondromyxoid fibroma 10.2 DES VIM
39 ameloblastoma 10.1
40 sarcoma 10.1
41 congenital granular cell tumor 10.1
42 rhabdoid tumor predisposition syndrome 1 10.1 DES VIM
43 papillary adenocarcinoma 10.1 PGR VIM
44 lung meningioma 10.1 ENO2 PGR
45 odontogenic myxoma 10.1 SERPINA3 VIM
46 meningioma, radiation-induced 10.1 PGR VIM
47 cervical clear cell adenocarcinoma 10.1 ENO2 PGR
48 bednar tumor 10.1 ENO2 VIM
49 papillary tumor of the pineal region 10.1 ENO2 VIM
50 cavernous hemangioma 10.1 DES VIM

Graphical network of the top 20 diseases related to Epulis:



Diseases related to Epulis

Symptoms & Phenotypes for Epulis

Drugs & Therapeutics for Epulis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Histological/ Immunohistological and Molecularpathological Types of Epulides and Central Giant Cell Lesions of the Jaws Recruiting NCT03829059

Search NIH Clinical Center for Epulis

Genetic Tests for Epulis

Anatomical Context for Epulis

MalaCards organs/tissues related to Epulis:

42
Breast, Tongue, Ovary, Bone, Testes, Myeloid, Spinal Cord

Publications for Epulis

Articles related to Epulis:

(show top 50) (show all 357)
# Title Authors Year
1
Congenital epulis: a rare case of feeding obstruction in a neonate. ( 31031062 )
2019
2
Congenital Granular Cell Epulis: Classic Presentation and Its Differential Diagnosis. ( 30888637 )
2019
3
A puzzling pregnancy epulis with aggressive bone loss mimicking malignant neoplasm: A case report. ( 30981907 )
2019
4
Peripheral adenomatoid odontogenic tumor in a cloak of an epulis: report of a rare case. ( 31077195 )
2019
5
Congenital Epulides-Spontaneous Regression. ( 30322699 )
2019
6
Congenital Epulis: A Case and Review of the Literature. ( 29962420 )
2018
7
Ossifying epulis in pseudohypo-parathyroidism: a case-based therapeutic approach. ( 30063154 )
2018
8
Congenital Granular Cell Epulis. ( 30881795 )
2018
9
Prenatal Diagnosis of Congenital Epulis: Implications for Delivery. ( 28026880 )
2017
10
Sclerotherapy for the recurrent granulomatous epulis with pingyangmycin. ( 28160580 )
2017
11
Post-intubation tension pneumothorax and pneumoperitoneum in a low birth weight neonate with giant epulis. ( 28216708 )
2017
12
Epulis-Like Presentation of Gingival Renal Cancer Metastasis. ( 28878662 )
2017
13
Minimally Invasive Excision of Epulides with a CO2 Laser: A Retrospective Study of 90 Patients. ( 28375684 )
2017
14
Congenital Epulis. ( 26933472 )
2016
15
Two variations of congenital epulis. ( 27280469 )
2016
16
Congenital epulis: A rare benign tumour. ( 28064302 )
2016
17
Epulis: a study of 92 cases with special emphasis on histopathological diagnosis and associated clinical data. ( 26578118 )
2016
18
Nonsurgical treatment of an epulis by photodynamic therapy. ( 26854720 )
2016
19
A study of cell proliferation using immunohistological staining: A case report of congenital granular cell epulis. ( 27497388 )
2016
20
Comparison of Carbon Dioxide Laser With Surgical Blade for Removal of Epulis Fissuratum. A Randomized Clinical Trial. ( 28144443 )
2016
21
Two- and three-dimensional ultrasound for assessing potential airway obstruction in congenital epulis. ( 25487070 )
2015
22
Congenital Epulis: A Rare Benign Jaw Tumour in a 2-Day-Old Male Baby. ( 26379808 )
2015
23
Congenital epulis of the newborn. ( 26980979 )
2015
24
Esthetic management of mucogingival defects after excision of epulis using laterally positioned flaps. ( 25315641 )
2015
25
Multiple congenital granular cell epulis: case report and immunohistochemical profile with emphasis on vascularization. ( 25722896 )
2015
26
Value of immunohistochemistry in diagnosing a rare case of maxillofacial plasma cell granuloma masquerading as a gingival epulis. ( 25729225 )
2015
27
Granular cell tumors and congenital granular cell epulis in children: Similar entities. ( 25783372 )
2015
28
Excision of epulis granulomatosa with diode laser in 8 years old boy. ( 25987975 )
2015
29
Periodontal plastic procedure for the management of the residual gingival defect after excision of an epulis. ( 26229282 )
2015
30
Removal of epulis fissuratum by Er,Cr:YSGG laser in comparison with the conventional method. ( 26492496 )
2015
31
Congenital epulis. ( 23896792 )
2014
32
Multiple congenital epulis in alveolar ridges of maxilla and mandible in a newborn: a rare case report. ( 24808964 )
2014
33
Congenital epulis: from birth to childhood. ( 24827956 )
2014
34
Congenital epulis in a newborn. ( 24941588 )
2014
35
Twin congenital epulis in the alveolar ridge of the maxilla and mandible in a newborn: a rare and interesting case. ( 25199202 )
2014
36
Congenital epulis in a newborn: a case report, immunoprofiling and review of literature. ( 25489201 )
2014
37
Congenital epulis of the newborn: difficult to diagnose but easy to treat. A case of unusual size. ( 25600926 )
2014
38
Congenital Epulis: a clinical case presentation. ( 28191214 )
2014
39
Massive fibrous epulis-a case report of a 10-year-old lesion. ( 24136676 )
2014
40
Congenital granular cell epulis. ( 24377822 )
2014
41
Management of geriatric patient with epulis fissuratum using liquid nitrogen cryosurgery: a case report. ( 24605008 )
2014
42
Metastatic uterine leiomyosarcoma in the upper buccal gingiva misdiagnosed as an epulis. ( 25386373 )
2014
43
Congenital giant epulis obstructing oral cavity: newborn emergency. ( 25396021 )
2014
44
Multiple congenital granular cell epulis in a female newborn: a case report. ( 25482350 )
2014
45
Congenital epulides: a rare case report. ( 25728118 )
2014
46
Prenatal diagnosis of congenital epulis by 2D/3D ultrasound and magnetic resonance. ( 23548590 )
2013
47
Spontaneous regression of a congenital epulis in a newborn. ( 23855175 )
2013
48
Evaluation of GLUT-1 in the granular cell tumour and congenital granular cell epulis. ( 23336292 )
2013
49
Epulis fissuratum: consequence of ill-fitting prosthesis. ( 23867882 )
2013
50
Laser-assisted surgery in oral medicine: treatment of fibrous epulis with diode 915 nm. ( 24353809 )
2013

Variations for Epulis

Expression for Epulis

Search GEO for disease gene expression data for Epulis.

Pathways for Epulis

Pathways related to Epulis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.81 DES VIM
2
Show member pathways
10.28 DES VIM

GO Terms for Epulis

Biological processes related to Epulis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 9.16 DES VIM
2 negative regulation of neuron projection development GO:0010977 8.96 VIM
3 positive regulation of collagen biosynthetic process GO:0032967 8.96 AMELX VIM
4 intermediate filament organization GO:0045109 8.62 DES VIM

Molecular functions related to Epulis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 AMELX DES PGR VIM

Sources for Epulis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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