MCID: EPL003
MIFTS: 30

Epulis

Categories: Cancer diseases, Oral diseases, Rare diseases

Aliases & Classifications for Epulis

MalaCards integrated aliases for Epulis:

Name: Epulis 12 15
Epulides 12 70
Gingival Polyp 12
Polyp of Gum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5337
MeSH 44 D005882
NCIt 50 C3948
SNOMED-CT 67 71708001
UMLS 70 C0266919

Summaries for Epulis

MalaCards based summary : Epulis, also known as epulides, is related to congenital epulis and myoblastoma. An important gene associated with Epulis is SERPINA3 (Serpin Family A Member 3). Affiliated tissues include bone, breast and skin.

Wikipedia : 73 Epulis (Greek: ἐπουλίς; plural epulides) is any tumor like enlargement (i.e. lump) situated on the... more...

Related Diseases for Epulis

Diseases in the Epulis family:

Congenital Epulis

Diseases related to Epulis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 215)
# Related Disease Score Top Affiliating Genes
1 congenital epulis 31.7 VIM SERPINA3 PGR KRT222 ENO2 DES
2 myoblastoma 30.9 ENO2 CD68
3 granular cell tumor 30.8 VIM SERPINA3 ENO2 DES CD68
4 fibroma 30.6 VIM SERPINA3 DES CD68
5 benign giant cell tumor 30.6 VIM SERPINA3 DES
6 fibromatosis 30.5 VIM DES
7 congenital granular cell tumor 30.3 NGFR ENO2 CD68
8 melanotic neuroectodermal tumor 30.3 VIM ENO2
9 hemangioma 30.2 VIM PGR ENO2 CD68
10 spindle cell sarcoma 30.2 VIM SERPINA3 DES
11 myofibroma 30.1 SERPINA3 DES
12 giant cell reparative granuloma 30.0 SERPINA3 CD68
13 skin benign neoplasm 29.9 SERPINA3 ENO2 CD68
14 leiomyosarcoma 29.6 VIM SERPINA3 PGR ENO2 DES
15 gingival overgrowth 11.0
16 infantile digital fibromatosis 10.4 VIM DES
17 adult cystic nephroma 10.4 PGR DES
18 cervical polyp 10.4 PGR DES
19 intravenous leiomyomatosis 10.4 PGR DES
20 endometrial mucinous adenocarcinoma 10.4 VIM PGR
21 vaginal glandular tumor 10.3 PGR ENO2
22 malignant fibrous histiocytoma of bone 10.3 SERPINA3 DES
23 intravascular papillary endothelial hyperplasia 10.3 VIM SERPINA3
24 spindle cell thymoma 10.3 ENO2 DES
25 parachordoma 10.3 VIM DES
26 vaginal endometrial stromal sarcoma 10.3 VIM PGR
27 lung meningioma 10.3 PGR ENO2
28 giant cell myocarditis 10.3 DES CD68
29 bednar tumor 10.3 VIM ENO2
30 syringocystadenoma papilliferum 10.3 SERPINA3 DES
31 angiolipoma 10.3 VIM DES
32 papillary tumor of the pineal region 10.3 VIM ENO2
33 glomangioma 10.3 VIM DES
34 spindle cell lipoma 10.3 VIM DES
35 reticulum cell sarcoma 10.3 VIM DES
36 malignant mesenchymoma 10.3 SERPINA3 DES
37 ovarian mucinous cystadenocarcinoma 10.3 VIM SERPINA3
38 mucinous cystadenocarcinoma 10.3 VIM SERPINA3
39 skull base cancer 10.3 SERPINA3 PGR
40 ewing sarcoma of bone 10.3 VIM ENO2
41 vagina sarcoma 10.3 VIM PGR
42 benign breast phyllodes tumor 10.3 VIM PGR
43 ectomesenchymoma 10.3 ENO2 DES
44 breast malignant phyllodes tumor 10.3 SERPINA3 PGR
45 heart lymphoma 10.3 VIM CD68
46 chondroid chordoma 10.3 VIM SERPINA3
47 odontogenic myxoma 10.3 VIM SERPINA3
48 verruciform xanthoma of skin 10.3 SERPINA3 CD68
49 proliferative fasciitis 10.3 SERPINA3 CD68
50 malignant inflammatory fibrous histiocytoma 10.3 SERPINA3 CD68

Graphical network of the top 20 diseases related to Epulis:



Diseases related to Epulis

Symptoms & Phenotypes for Epulis

Drugs & Therapeutics for Epulis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Retrospective Clinico-pathological Examinations on Different Histological/ Immunohistological and Molecularpathological Types of Epulides and Central Giant Cell Lesions of the Jaws Active, not recruiting NCT03829059

Search NIH Clinical Center for Epulis

Genetic Tests for Epulis

Anatomical Context for Epulis

MalaCards organs/tissues related to Epulis:

40
Bone, Breast, Skin, Tongue, Smooth Muscle, Pancreas, Ovary

Publications for Epulis

Articles related to Epulis:

(show top 50) (show all 875)
# Title Authors PMID Year
1
Odontogenic and Developmental Oral Lesions in Pediatric Patients. 61
33723756 2021
2
Spontaneous oral tumours in 18 rabbits (2005-2015). 61
31737910 2021
3
Role of prenatal imaging in the diagnosis and management of fetal facio-cervical masses. 61
33446872 2021
4
Diode Laser Management of Primary Extranasopharyngeal Angiofibroma Presenting as Maxillary Epulis: Report of a Case and Literature Review. 61
33401498 2021
5
Therapeutic effects of diode laser on vascular epulis in esthetic area. 61
33642746 2021
6
A New Look at the History of Peripheral Ameloblastoma. 61
32451874 2020
7
[Treatment strategy for pregnancy epulis]. 61
33377354 2020
8
Gingival Plasma Cell Granuloma: A case Report of Multiple Lesions. 61
33378465 2020
9
Oral Lesions in Captive Nondomestic Felids With a Focus on Odontogenic Lesions. 61
33016248 2020
10
Ex-Utero Intrapartum Treatment (EXIT): indications and outcome in fetal cervical and oropharyngeal masses. 61
33028259 2020
11
Ascher Syndrome: Acquired Double Lower Lip Combined With Epulis Fissuratum. 61
32472894 2020
12
Vascular endothelial growth factor (VEGF) and Endocrine gland-VEGF (EG-VEGF) are down regulated in head and neck cancer. 61
32516473 2020
13
Large Congenital Epulis in a Newborn: Diagnosis and Management. 61
31132898 2020
14
Large Congenital Epulis: A Neonatal Tumour with Striking Appearance, but Simple Management. 61
32779496 2020
15
[Congenital giant cell epulis: Importance of the prenatal diagnosis]. 61
31378639 2020
16
A retrospective analysis of oral and maxillofacial biopsied specimens in Malaysian newborns and infants. 61
32815206 2020
17
Coexistence of hyperparathyroidism and peripheral giant cell granuloma of the jaw: A rare case report. 61
32984187 2020
18
A puzzling pregnancy epulis with aggressive bone loss mimicking malignant neoplasm: A case report. 61
30981907 2020
19
Intubation with the video laryngoscope Insighters in a patient with giant epulis. 61
32089293 2020
20
Congenital Granular Cell Epulis: Classic Presentation and Its Differential Diagnosis. 61
30888637 2020
21
The RAS-PI3K-AKT-NF-κB pathway transcriptionally regulates the expression of BCL2 family and IAP family genes and inhibits apoptosis in fibrous epulis. 61
31743516 2020
22
Comparative Evaluation of SMAD-2 Expression in Oral Submucous Fibrosis and Reactive Oral Lesions. 61
32102517 2020
23
[Characteristic expression of apoptotic genes in epulis]. 61
32524117 2020
24
Histopathological analysis of the differential diagnosis of peripheral odontogenic fibroma from fibrous epulis. 61
31669716 2019
25
[Tooth and pregnancy, a public health issue]. 61
31706894 2019
26
The clinical application of partial removal periodontal surgery in the therapy of epulis. 61
31277111 2019
27
Congenital Oral Masses: An Anatomic Approach to Diagnosis. 61
31283464 2019
28
Congenital epulis: a rare case of feeding obstruction in a neonate. 61
31031062 2019
29
Peripheral adenomatoid odontogenic tumor in a cloak of an epulis: report of a rare case. 61
31077195 2019
30
Diagnosis and treatment of oral focal mucinosis: a case series. 61
31023388 2019
31
Congenital Epulides-Spontaneous Regression. 61
30322699 2019
32
Oral Health Status and Treatment Needs of Pregnant Women Attending Antenatal Clinics in KwaZulu-Natal, South Africa. 61
30956659 2019
33
Whitish-Yellow Tumor on its Characteristic Cut Surface: A Case Report of Congenital Granular Cell Epulis. 61
31211292 2019
34
[Clinical evaluation and comparison of three surgical procedures for treatment of root surface exposure after epulis resection]. 61
30630256 2019
35
Congenital Granular Cell Epulis. 61
30881795 2018
36
Ossifying epulis in pseudohypo-parathyroidism: a case-based therapeutic approach. 61
30063154 2018
37
[Multiple pregnancy epulides: a case report]. 61
30182578 2018
38
[DENTAL CARE DURING PREGNANCY]. 61
29804341 2018
39
Comparsion of staining characteristics of Toto bodies. 61
29781718 2018
40
Congenital Epulis: A Case and Review of the Literature. 61
29962420 2018
41
An uncommon case of fibrolipoma. 61
29256473 2017
42
A report on the clinical-pathological correlations of 788 gingival lesion. 61
29053652 2017
43
Minimally Invasive Excision of Epulides with a CO2 Laser: A Retrospective Study of 90 Patients. 61
28375684 2017
44
[Maxillary, buccal and dental expressions of hyperparathyroidisms]. 61
28579010 2017
45
Successful management of rare gingival metastasis from gastric adenocarcinoma: a case report and literature review. 61
28764790 2017
46
Idiopathic peripheral ossifying fibroma in a young adolescent girl: A very rare clinical presentation. 61
29456309 2017
47
The application of diode laser in the treatment of oral soft tissues lesions. A literature review. 61
28828162 2017
48
Epulis-Like Presentation of Gingival Renal Cancer Metastasis. 61
28878662 2017
49
Congenital Gingival Granular Cell Tumor: A Case Report. 61
28293667 2017
50
Neumann's Tumor: A Case Report. 61
28579714 2017

Variations for Epulis

Expression for Epulis

Search GEO for disease gene expression data for Epulis.

Pathways for Epulis

GO Terms for Epulis

Biological processes related to Epulis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of collagen biosynthetic process GO:0032967 8.96 VIM AMELX
2 intermediate filament organization GO:0045109 8.62 VIM DES

Sources for Epulis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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