MCID: ERY004
MIFTS: 49

Erysipelas

Categories: Infectious diseases, Rare diseases, Skin diseases

Aliases & Classifications for Erysipelas

MalaCards integrated aliases for Erysipelas:

Name: Erysipelas 12 74 52 29 54 43 15 17 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:11330
ICD9CM 34 035
MeSH 43 D004886
SNOMED-CT 67 44653001
ICD10 32 A46
UMLS 71 C0014733

Summaries for Erysipelas

MalaCards based summary : Erysipelas is related to venous insufficiency and familial mediterranean fever, and has symptoms including exanthema An important gene associated with Erysipelas is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and Allograft rejection. The drugs Penicillin V and Amoxicillin have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast, and related phenotypes are cardiovascular system and hematopoietic system

Wikipedia : 74 Erysipelas, also known as St. Anthony's fire, is a relatively common bacterial infection of the... more...

Related Diseases for Erysipelas

Diseases related to Erysipelas via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 767)
# Related Disease Score Top Affiliating Genes
1 venous insufficiency 31.1 ELN ELANE CRP
2 familial mediterranean fever 30.6 TNF MVK MEFV IL6 IL1RN IL1B
3 enthesopathy 30.5 TNF MEFV CRP
4 thrombophlebitis 30.2 TNF CRP CD40LG
5 bullous impetigo 30.1 IL6 CALCA
6 bursitis 30.1 TNF IL1B CRP
7 plague 30.1 TNF IL6 IL1B
8 scarlet fever 30.1 TNF MYOM2 CRP CD40LG
9 neurogenic arthropathy 30.0 CRP CALCA
10 pustulosis of palm and sole 30.0 TNF IL1RN CRP
11 endocarditis 30.0 TNF PIK3C2A IL6 CRP CAT
12 acute myocarditis 29.9 TNF IL1B CRP
13 pyomyositis 29.9 PIK3C2A MYOM2 CRP
14 disseminated intravascular coagulation 29.9 TNF PIK3C2A IL6 ELANE CRP
15 irritant dermatitis 29.8 TNF IL6 IL1B
16 myelitis 29.8 TNF IL6 CD40LG
17 tularemia 29.8 TNF IL1B CD40LG
18 peripheral artery disease 29.7 TNF IL6 CRP
19 pyoderma gangrenosum 29.7 TNF MVK MEFV IL1RN
20 urticaria 29.7 TNF IL6 CRP CD40LG
21 neuritis 29.7 TNF IL6 IL1B
22 compartment syndrome 29.6 TNF PIK3C2A IL6 CRP
23 varicose veins 29.6 TNF IL6 ELN
24 leukostasis 29.6 TNF IL6 IL1B
25 lymphadenitis 29.5 TNF IL1B CRP
26 vasculitis 29.5 TNF MEFV IL6 ELANE CRP CD40LG
27 endophthalmitis 29.5 TNF IL6 IL1B CRP
28 spondylitis 29.5 TNF IL6 IL1RN CRP
29 purpura 29.5 TNF MEFV IL6 CRP CD40LG
30 prosthetic joint infection 29.5 IL6 IL1B CRP
31 allergic contact dermatitis 29.4 TNF IL6 IL1B
32 ischemia 29.4 SOD2 SOD1 PIK3C2A IL1RN CAT
33 chikungunya 29.4 TNF IL6 IL1B
34 carbuncle 29.4 TNF IL6 IL1B CAT
35 dermatitis 29.4 TNF IL6 IL2 IL1B
36 panuveitis 29.4 TNF IL6 CRP CD40LG
37 impetigo 29.4 PI3 MYOM2 IL6 ELANE CD40LG CALCA
38 suppurative otitis media 29.3 IL1B CRP CD40LG
39 alcoholic liver cirrhosis 29.3 TNF SOD2 IL6 IL1B
40 fasciitis 29.3 TNF MYOM2 IL6 IL2 IL1RN CRP
41 heart valve disease 29.2 MYOM2 IL1B ELN CRP
42 cellulitis 29.2 TNF IL6 IL2 IL1B CRP CD40LG
43 osteomyelitis 29.2 TNF IL6 IL1RN IL1B CALCA
44 relapsing polychondritis 29.2 IL6 IL2 CRP
45 thyroiditis 29.2 TNF IL6 IL2 CALCA
46 diphtheria 29.2 TNF IL2 IL1B CD40LG
47 keratitis, hereditary 29.2 TNF IL6 IL1B
48 typhoid fever 29.1 TNF IL6 IL1B CRP CD40LG
49 encephalitis 29.1 TNF IL6 IL1B CD40LG
50 synovitis 29.1 TNF IL6 IL1RN IL1B CRP

Graphical network of the top 20 diseases related to Erysipelas:



Diseases related to Erysipelas

Symptoms & Phenotypes for Erysipelas

UMLS symptoms related to Erysipelas:


exanthema

MGI Mouse Phenotypes related to Erysipelas:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.11 BDKRB1 CD40LG CRP IL1B IL1RN IL2
2 hematopoietic system MP:0005397 10.1 BDKRB1 CD40LG ELANE IL1B IL1RN IL2
3 homeostasis/metabolism MP:0005376 10.1 BDKRB1 CAT CD40LG CRP ELANE IL1B
4 immune system MP:0005387 9.97 BDKRB1 CD40LG CRP ELANE IL1B IL1RN
5 integument MP:0010771 9.65 BDKRB1 CD40LG ELANE IL1B IL1RN IL6
6 neoplasm MP:0002006 9.23 CAT ELANE IL1B IL2 IL6 SOD1

Drugs & Therapeutics for Erysipelas

Drugs for Erysipelas (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 65)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Penicillin V Approved, Vet_approved Phase 4 87-08-1 6869
2
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
3 penicillins Phase 4
4 Anti-Bacterial Agents Phase 4
5 Anti-Infective Agents Phase 4
6 Floxacillin Phase 4
7 Antibiotics, Antitubercular Phase 4
8
Tedizolid phosphate Approved Phase 3 856867-55-5
9
Tedizolid Approved, Investigational Phase 3 856866-72-3
10
Delafloxacin Approved, Investigational Phase 3 189279-58-1
11
Aztreonam Approved Phase 3 78110-38-0 5742832 5362041
12
Linezolid Approved, Investigational Phase 3 165800-03-3 441401
13
Cephalexin Approved, Investigational, Vet_approved Phase 3 15686-71-2 27447
14
Cefazolin Approved Phase 3 25953-19-9 656510 33255
15
Metronidazole Approved Phase 3 443-48-1 4173
16
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
17
Prednisolone phosphate Approved, Vet_approved Phase 2, Phase 3 302-25-0
18
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3 83-43-2 6741
19
Methylprednisolone hemisuccinate Approved Phase 2, Phase 3 2921-57-5
20
Zoledronic Acid Approved Phase 2, Phase 3 118072-93-8 68740
21
Prednisolone Approved, Vet_approved Phase 2, Phase 3 50-24-8 5755
22 Prednisolone acetate Approved, Vet_approved Phase 2, Phase 3 52-21-1
23
Prednisolone hemisuccinate Experimental Phase 2, Phase 3 2920-86-7
24 Hormones Phase 2, Phase 3
25 glucocorticoids Phase 2, Phase 3
26 Antineoplastic Agents, Hormonal Phase 2, Phase 3
27 Hormone Antagonists Phase 2, Phase 3
28 Anti-Inflammatory Agents Phase 2, Phase 3
29 Clindamycin phosphate Phase 3
30 Clindamycin palmitate Phase 3
31 Methylprednisolone Acetate Phase 2, Phase 3
32 Antiemetics Phase 2, Phase 3
33 Neuroprotective Agents Phase 2, Phase 3
34 Protective Agents Phase 2, Phase 3
35 Gastrointestinal Agents Phase 2, Phase 3
36 Diphosphonates Phase 2, Phase 3
37
leucovorin Approved Phase 2 58-05-9 6006 143
38
Sulfamethoxazole Approved Phase 2 723-46-6 5329
39
Trimethoprim Approved, Vet_approved Phase 2 738-70-5 5578
40
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
41
Folic acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
42 methicillin Phase 2
43 Antiparasitic Agents Phase 2
44 Antiprotozoal Agents Phase 2
45 Cytochrome P-450 Enzyme Inhibitors Phase 2
46 Folic Acid Antagonists Phase 2
47 Vitamin B Complex Phase 2
48 Folate Phase 2
49 Trimethoprim, Sulfamethoxazole Drug Combination Phase 2
50 Vitamin B9 Phase 2

Interventional clinical trials:

(show all 20)
# Name Status NCT ID Phase Drugs
1 A Multicenter, Randomized Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in the Treatment of Cellulitis or Erysipelas Completed NCT00295178 Phase 4 Daptomycin;Vancomycin
2 Randomised Controlled Trial to Investigate Whether Prophylactic Antibiotics Can Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg (PATCH I) Completed NCT00552799 Phase 4 Penicillin VK
3 Randomized Non Inferiority Study Comparing Short Course of Oral Amoxicillin to One of the Usual Treatments of Lower Leg Erysipelas Terminated NCT01059123 Phase 4 Amoxicillin;Amoxicillin
4 Duration of Antibiotic Therapy for Cellulitis (DANCE): a Randomized Controlled Trial Comparing 6 to 12 Days of Antibiotic Therapy for Patients Hospitalized With Cellulitis Terminated NCT02032654 Phase 4 Flucloxacillin;Placebo (for flucloxacillin)
5 A Phase 3, Multicenter, Randomized, Double-blind, Active-controlled Study to Evaluate the Efficacy and Safety of Delafloxacin Compared With Vancomycin + Aztreonam in Patients With Acute Bacterial Skin and Skin Structure Infections Completed NCT01811732 Phase 3 Delafloxacin;Vancomycin;Aztreonam;Placebo
6 Phase 3 Study of IV to Oral 6-Day Tedizolid Phosphate Compared With 10-day Comparator in Subjects 12 to < 18 Years With cSSTI. Completed NCT02276482 Phase 3 Tedizolid Phophate;Antibiotic comparator;Aztreonam;Metronidazole
7 Zoledronic Acid or Methylprednisolone in the Management of Active Charcot's Neuroarthropathy of Foot in Patients With Diabetes Mellitus: A Randomized, Double-blind, Placebo Controlled Trial Completed NCT03289338 Phase 2, Phase 3 Zoledronic Acid;Methylprednisolone;Placebos
8 Fat Grafting Used for the Treatment of Breast Cancer Related Lymphedema in China Unknown status NCT02981485 Phase 2
9 Phase 2 Open-Label Safety and Exploratory Skin Lesion Measurement Study of 6-Day Oral TR-701 FA in Skin Abscess and Cellulitis Patients Completed NCT01519778 Phase 2 TR701 FA
10 A Randomized, Parallel Group, Controlled Study to Assess the Efficacy and Safety of NMBM in the Treatment of Subjects With a Post-cellulitis and Venous Leg Ulcer Completed NCT01770509 Phase 1, Phase 2
11 A Randomized, Double-Blind Study Comparing Three Dosing Regimens of Brilacidin to Daptomycin in the Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Completed NCT02052388 Phase 2 Daptomycin;Brilacidin
12 Randomized, Double-Blind Trial of Clindamycin, Trimethoprim-Sulfamethoxazole, or Placebo for Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureus Completed NCT00730028 Phase 2 Trimethoprim-sulfamethoxazole;Clindamycin
13 Short and Long Term Outcomes of Doxycycline Versus Trimethoprim-Sulfamethoxazole for Treatment of Uncomplicated Skin and Soft Tissue Infections Active, not recruiting NCT03637400 Phase 2 TMP-SMX;DOXY
14 Utility of Prednisone in the Treatment of Cellulitis Withdrawn NCT00893048 Phase 2 Prednisone;Placebo Oral Tablet
15 Tele-dermatology of Skin Cancer: a Randomized Trial Comparing Remote Assessment With Conventional Visits in a Cohort of Local Health Authority Employees in the Province of Bergamo (the Shoot the Mole Study) Completed NCT02902822
16 Effectiveness of Vitamin D Supplementation to Reduce Injury and Illness in the UK Armed Forces With Specific Reference to Stress Fracture Risk Reduction Recruiting NCT03963128
17 Necrotizing Bacterial Dermohypodermitis-necrotizing Fasciitis (DHBN-FN) Mono- or Multi-microbial Streptococcus Beta-haemolytic: Study of Carriage in Patients and Their Entourage Not yet recruiting NCT03976024
18 Musculoskeletal Ultrasound of the Ankles in Erysipelas-like Erythema of Familial Mediterranean Fever Not yet recruiting NCT03917277
19 Retrospective Effectiveness Study of Dalbavancin and Other Standard of Care of the Same Class (i.v. Lipo and Glyco-peptides) in Patients With ABSSSI Not yet recruiting NCT04298463 Xydalba;vancomycin, teicoplanin or daptomycin
20 DART: "Sivextro® in Acute Bacterial Skin anD Skin Structure Infection (ABSSSI) in Hospitalized Patients. A Global ObseRvational STudy." Terminated NCT02991131 Tedizolid (Sivextro, BAY1192631);Linezolid

Search NIH Clinical Center for Erysipelas

Cochrane evidence based reviews: erysipelas

Genetic Tests for Erysipelas

Genetic tests related to Erysipelas:

# Genetic test Affiliating Genes
1 Erysipelas 29

Anatomical Context for Erysipelas

MalaCards organs/tissues related to Erysipelas:

40
Skin, Testes, Breast, Lymph Node, Neutrophil, Tonsil, Colon

Publications for Erysipelas

Articles related to Erysipelas:

(show top 50) (show all 2129)
# Title Authors PMID Year
1
The importance of serum creatine phosphokinase level in the early diagnosis and microbiological evaluation of necrotizing fasciitis. 61 54
15482296 2004
2
The importance of serum creatine phosphokinase level in the early diagnosis, and as a prognostic factor, of Vibrio vulnificus infection. 61 54
11531792 2001
3
Levels of skin-derived antileukoproteinase (SKALP)/elafin in serum correlate with disease activity during treatment of severe psoriasis with cyclosporin A. 54 61
7829874 1995
4
Influence of COVID-19 pandemic on hospitalizations at the tertiary dermatology department in south-west Poland. 61
32478949 2020
5
Suspected adverse reaction to erysipelas vaccine in sheep. 61
32527900 2020
6
Comparative Genome Analysis of a Pathogenic Erysipelothrix rhusiopathiae Isolate WH13013 from Pig Reveals Potential Genes Involve in Bacterial Adaptions and Pathogenesis. 61
32512708 2020
7
Merkel cell carcinoma-derived Erysipelas carcinomatosum. 61
32118331 2020
8
Phase 1 LymfactinⓇ Study: Short-term Safety of Combined Adenoviral VEGF-C and Lymph Node Transfer Treatment for Upper Extremity Lymphedema. 61
32513642 2020
9
Lactoferrin: A Critical Mediator of Both Host Immune Response and Antimicrobial Activity in Response to Streptococcal Infections. 61
32329605 2020
10
Development of a Multiplex PCR-Based Assay for Rapid Serotyping of Erysipelothrix Species. 61
32269099 2020
11
Antibiotic prescribing among patients with severe infectious diseases in two private sector hospitals in Central India - a time series analysis over 10 years. 61
32404055 2020
12
[Indication of bloodletting therapy based on multi-dimensional evidence assessment]. 61
32275379 2020
13
Milian's ear sign of erysipelas. 61
32241881 2020
14
Is coverage of S. aureus necessary in cellulitis/erysipelas? A literature review. 61
31845187 2020
15
Erysipelas after Femoro-Tibial Bypass Surgery. 61
32274374 2020
16
Frequency, characteristics, and clinical determinants of 'prodrome' in familial Mediterranean fever patients. 61
31478409 2020
17
Cutaneous leishmaniasis: A great imitator. 61
32513395 2020
18
A comprehensive molecular analysis and genotype-phenotype correlation in patients with familial mediterranean fever. 61
31989427 2020
19
Association of Atopic Dermatitis With Bacterial, Fungal, Viral, and Sexually Transmitted Skin Infections. 61
32049716 2020
20
A review of the antimicrobial potential of herbal drugs used in popular Italian medicine (1850s-1950s) to treat bacterial skin diseases. 61
31790819 2020
21
Osteomyelitis complicating secondarily infected atopic eczema: two case reports and a narrative literature review. 61
32008574 2020
22
Associations of cutaneous and extracutaneous infections with hidradenitis suppurativa in U.S. children and adults. 61
31049925 2020
23
Erysipelas septicaemia in piglets born to vaccinated gilts. 61
32054802 2020
24
Management and biosecurity practices on pig farms in the Western Highlands of Cameroon (Central Africa). 61
31682081 2020
25
Genome sequence of multidrug-resistant Erysipelothrix rhusiopathiae ZJ carrying several acquired antimicrobial resistance genes. 61
32119991 2020
26
Skin Infections and Outpatient Burn Management: Bacterial Skin Infections. 61
31995349 2020
27
Erysipelas-like presentation of Wells' syndrome (eosinophilic cellulitis). 61
31995962 2020
28
The rash that presents as a red swollen face. 61
32197750 2020
29
Age of onset as an influencing factor for disease severity in children with familial Mediterranean fever. 61
31999206 2020
30
Comparison of Pediatric Familial Mediterranean Fever Patients Carrying Only E148Q Variant With the Ones Carrying Homozygous Pathogenic Mutations. 61
31972733 2020
31
Erysipelas on surgical scar: a case report. 61
32499847 2020
32
Erysipelothrix Spp.: Past, Present, and Future Directions in Vaccine Research. 61
32351978 2020
33
Repetitive cellulitis caused by Streptococcus agalactiae isolates with different genotypic and phenotypic features in a patient having upper extremity with lymphedema after mastectomy and axillary lymph node dissection. 61
32420032 2020
34
In Search of Risk Factors for Recurrent Erysipelas and Cellulitis of the Lower Limb: A Cross-Sectional Study of Epidemiological Characteristics of Patients Hospitalized due to Skin and Soft-Tissue Infections. 61
32454817 2020
35
Calculated initial parenteral treatment of bacterial infections: Skin and soft tissue infections. 61
32373436 2020
36
[Complex treatment of pyoderma gangrenosum after minor trauma and primary surgical intervention with suspected necrotizing fasciitis]. 61
31392345 2020
37
Flucloxacillin-Induced Hepatotoxicity - Association with HLA-B*5701. 61
32130375 2020
38
Genomic and Immunogenic Protein Diversity of Erysipelothrix rhusiopathiae Isolated From Pigs in Great Britain: Implications for Vaccine Protection. 61
32231655 2020
39
[Characteristics of chronic wounds in substance abuse: A retrospective study of 58 patients]. 61
31648848 2019
40
Human Orf: An Under-recognized Entity. 61
31969245 2019
41
Vasculitis Mimicking Pseudo Erysipelas in Systemic Lupus Erythematosus. 61
31580463 2019
42
A putative transcription regulator involved in the virulence attenuation of an acriflavine-resistant vaccine strain of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas. 61
31767066 2019
43
Genome-Wide Identification of Virulence Genes in Erysipelothrix rhusiopathiae: Use of a Mutant Deficient in a tagF Homolog as a Safe Oral Vaccine against Swine Erysipelas. 61
31548316 2019
44
Prevalence of MEFV gene mutations in a large cohort of patients with suspected familial Mediterranean fever in Central Anatolia. 61
31804137 2019
45
The influence of genotype on disease severity and concomitant diseases in familial Mediterranean fever patients. 61
31603074 2019
46
Dermatosis: Morbidity and mortality at the University Hospital Center of Brazzaville. 61
31884997 2019
47
Wild boars: A potential source of Erysipelothrix rhusiopathiae infection in Japan. 61
31373400 2019
48
Impact of a Live Attenuated Classical Swine Fever Virus Introduced to Jeju Island, a CSF-Free Area. 61
31756940 2019
49
Colonization of β-hemolytic streptococci in patients with erysipelas-a prospective study. 61
31292789 2019
50
Erysipelothrix Septicaemia and Hepatitis in a Colony of Humboldt Penguins (Spheniscus humboldti). 61
31690415 2019

Variations for Erysipelas

Expression for Erysipelas

Search GEO for disease gene expression data for Erysipelas.

Pathways for Erysipelas

Pathways related to Erysipelas according to GeneCards Suite gene sharing:

(show all 36)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.98 TNF PI3 MEFV IL6 IL2 IL1RN
2
Show member pathways
12.81 TNF IL6 IL2 IL1B CD40LG
3
Show member pathways
12.67 TNF IL6 IL2 IL1B CD40LG
4
Show member pathways
12.55 TNF IL6 IL2 IL1B CD40LG
5 12.51 TNF IL2 IL1RN IL1B CD40LG
6 12.2 TNF MEFV IL6 IL1B
7
Show member pathways
12.18 TNF IL6 IL2 IL1B
8 12.13 TNF IL6 IL1RN IL1B
9 11.93 TNF IL6 IL2 IL1B
10
Show member pathways
11.84 TNF IL6 IL2 IL1B
11 11.8 TNF MEFV IL6 IL2 IL1B
12 11.74 TNF IL2 IL1B
13 11.72 TNF IL6 IL1B
14
Show member pathways
11.72 TNF IL2 CD40LG
15 11.71 SOD2 SOD1 MVK CAT
16 11.63 TNF IL6 IL2 IL1B
17 11.58 TNF IL6 IL1B
18
Show member pathways
11.56 SOD2 SOD1 CAT
19
Show member pathways
11.56 TNF SOD2 SOD1 IL6 IL2 IL1B
20 11.52 TNF IL6 IL2
21 11.49 TNF IL2 IL1B
22 11.48 TNF IL6 ELANE
23 11.43 TNF IL6 IL1B CD40LG
24 11.4 TNF IL6 IL1RN IL1B
25
Show member pathways
11.35 TNF IL6 IL2 IL1B CD40LG
26 11.34 TNF IL6 IL1B
27 11.32 TNF IL6 IL1B CALCA
28 11.3 SOD1 IL6 IL1B
29 11.29 TNF IL6 IL1B
30 11.24 TNF IL6 IL1B
31 11.2 SOD2 SOD1 CAT
32 11.19 TNF IL6 IL1B
33 11.15 TNF IL6 IL1B ELN CALCA
34 11.02 TNF IL6 IL2 IL1B
35 10.96 TNF IL6 IL2 IL1B ELN CD40LG
36 10.93 TNF IL6 CRP

GO Terms for Erysipelas

Cellular components related to Erysipelas according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.8 TNF SOD1 PI3 IL6 IL2 IL1RN
2 extracellular space GO:0005615 9.44 TNF SOD1 PI3 IL6 IL2 IL1RN

Biological processes related to Erysipelas according to GeneCards Suite gene sharing:

(show all 35)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 10.06 TNF IL6 IL1B CRP AZU1
2 negative regulation of apoptotic process GO:0043066 10.03 SOD1 IL6 IL2 CD40LG CAT AZU1
3 immune response GO:0006955 10.01 TNF IL6 IL2 IL1RN IL1B CD40LG
4 cytokine-mediated signaling pathway GO:0019221 9.95 TNF IL6 IL2 IL1RN IL1B
5 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.84 TNF IL6 IL2
6 response to glucocorticoid GO:0051384 9.83 TNF IL6 IL1RN
7 regulation of blood pressure GO:0008217 9.82 SOD2 SOD1 CALCA
8 positive regulation of smooth muscle cell proliferation GO:0048661 9.82 TNF IL6 ELANE
9 antimicrobial humoral response GO:0019730 9.81 PI3 ELANE AZU1
10 positive regulation of interleukin-6 production GO:0032755 9.8 TNF IL6 IL1B
11 positive regulation of interferon-gamma production GO:0032729 9.77 TNF IL2 IL1B
12 embryo implantation GO:0007566 9.77 SOD1 IL1B CALCA
13 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.77 TNF IL6 IL1B CD40LG CAT
14 positive regulation of T cell proliferation GO:0042102 9.71 IL6 IL2 IL1B CD40LG
15 positive regulation of interleukin-8 production GO:0032757 9.7 TNF IL1B CALCA
16 negative regulation of neurogenesis GO:0050768 9.69 TNF IL6 IL1B
17 protein kinase C-activating G protein-coupled receptor signaling pathway GO:0007205 9.67 IL2 BDKRB1 AZU1
18 positive regulation of interleukin-1 beta biosynthetic process GO:0050725 9.66 TNF AZU1
19 regulation of establishment of endothelial barrier GO:1903140 9.65 TNF IL1B
20 negative regulation of interleukin-1-mediated signaling pathway GO:2000660 9.64 IL6 IL1RN
21 regulation of immunoglobulin secretion GO:0051023 9.62 TNF CD40LG
22 cellular extravasation GO:0045123 9.62 TNF AZU1
23 positive regulation of fever generation GO:0031622 9.61 TNF IL1B
24 response to superoxide GO:0000303 9.61 SOD2 SOD1
25 positive regulation of glial cell proliferation GO:0060252 9.61 TNF IL6 IL1B
26 sequestering of triglyceride GO:0030730 9.58 TNF IL1B
27 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.58 TNF IL1B
28 negative regulation of chemokine biosynthetic process GO:0045079 9.57 IL6 ELANE
29 negative regulation of inflammatory response GO:0050728 9.55 SOD1 MVK MEFV IL2 ELANE
30 positive regulation of neuroinflammatory response GO:0150078 9.5 TNF IL6 IL1B
31 positive regulation of fractalkine biosynthetic process GO:0050754 9.48 TNF AZU1
32 fractalkine production GO:0032603 9.46 TNF AZU1
33 negative regulation of lipid storage GO:0010888 9.43 TNF IL6 CRP
34 inflammatory response GO:0006954 9.32 TNF MEFV IL6 IL1RN IL1B CRP
35 positive regulation of phagocytosis GO:0050766 9.26 TNF SOD1 IL1B AZU1

Molecular functions related to Erysipelas according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.56 TNF SOD2 SOD1 MVK MEFV CRP
2 superoxide dismutase activity GO:0004784 9.16 SOD2 SOD1
3 cytokine activity GO:0005125 9.1 TNF IL6 IL2 IL1RN IL1B CD40LG

Sources for Erysipelas

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....