MCID: ERY002
MIFTS: 33

Erythema Infectiosum

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Erythema Infectiosum

Summaries for Erythema Infectiosum

MedlinePlus : 44 Fifth disease is a viral infection caused by parvovirus B19. The virus only infects humans; it's not the same parvovirus that dogs and cats can get. Fifth disease mostly affects children. Symptoms can include a low fever, cold symptoms, and a headache. Then you get a red rash on your face. It looks like a "slapped cheek." The rash can spread to the arms, legs, and trunk. Adults who get it might also have joint pain and swelling. Fifth disease spreads easily, through saliva and mucus. You can get it when an infected person coughs or sneezes. Frequently washing your hands might help prevent getting the virus. Most people become immune to the virus after having it once. Fifth disease is usually mild and goes away on its own. However, it can be serious if you Are pregnant Are anemic Have cancer or a weak immune system Centers for Disease Control and Prevention

MalaCards based summary : Erythema Infectiosum, also known as fifth disease, is related to parvovirus antenatal infection and myositis, and has symptoms including fever, pruritus and exanthema. An important gene associated with Erythema Infectiosum is CD40LG (CD40 Ligand). The drugs Vaccines and Adjuvants, Immunologic have been mentioned in the context of this disorder. Affiliated tissues include skin, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

CDC : 3 Describes the virus, illnesses caused by the virus, how it spreads, how to reduce your chance of infection...

Wikipedia : 77 Erythema infectiosum or fifth disease is one of several possible manifestations of infection by... more...

Related Diseases for Erythema Infectiosum

Graphical network of the top 20 diseases related to Erythema Infectiosum:



Diseases related to Erythema Infectiosum

Symptoms & Phenotypes for Erythema Infectiosum

UMLS symptoms related to Erythema Infectiosum:


fever, pruritus, exanthema

GenomeRNAi Phenotypes related to Erythema Infectiosum according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-117 9.23 LIG3 PIN1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-142 9.23 PIN1
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-181 9.23 PIN1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-206 9.23 PIN1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.23 PIN1
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.23 LIG3
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.23 LIG3

MGI Mouse Phenotypes related to Erythema Infectiosum:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.43 APOH CD40LG FKTN LIG3 PIN1 SLC45A2
2 nervous system MP:0003631 9.02 CD40LG E2F6 FKTN LIG3 PIN1

Drugs & Therapeutics for Erythema Infectiosum

Drugs for Erythema Infectiosum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 1, Phase 2
2 Adjuvants, Immunologic Phase 1, Phase 2
3 Immunologic Factors Phase 1, Phase 2
4 MF59 oil emulsion Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 B-19 Parvovirus Vaccine Study Terminated NCT00379938 Phase 1, Phase 2 Placebo
2 A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease Completed NCT02261480

Search NIH Clinical Center for Erythema Infectiosum

Cochrane evidence based reviews: erythema infectiosum

Genetic Tests for Erythema Infectiosum

Anatomical Context for Erythema Infectiosum

MalaCards organs/tissues related to Erythema Infectiosum:

42
Skin

Publications for Erythema Infectiosum

Articles related to Erythema Infectiosum:

(show top 50) (show all 121)
# Title Authors Year
1
Clinical management of an adult with erythema infectiosum: a retrospective case report. ( 31057177 )
2019
2
Molecular diversity of human parvovirus B19 during two outbreaks of erythema infectiosum in Brazil. ( 27914222 )
2017
3
Acute hepatitis and myositis associated with Erythema infectiosum by Parvovirus B19 in an adolescent. ( 24410941 )
2014
4
Quantitation of human parvovirus B19 DNA in erythema infectiosum and aplastic crisis. ( 24962467 )
2014
5
Epidemiological and clinical features of erythema infectiosum in children in Novi Sad from 2000 to 2009. ( 24450250 )
2013
6
Acute glomerulonephritis in an immunocompetent elderly woman after contact with a child who had been diagnosed as erythema infectiosum. ( 22892503 )
2012
7
Erythema infectiosum rash. ( 21532111 )
2011
8
Erythema infectiosum: recognizing the many faces of fifth disease. ( 19601449 )
2009
9
Exposure to fifth disease in pregnancy. ( 20008596 )
2009
10
Prolonged parvovirus b19 viremia in spite of neutralizing antibodies after erythema infectiosum in pregnancy. ( 16940737 )
2007
11
Erythema infectiosum following generalized petechial eruption induced by human parvovirus B19. ( 16608124 )
2006
12
Detection of parvovirus B19 in a case of erythema infectiosum with myositis. ( 17033121 )
2006
13
Erythema infectiosum in children. A Clinical study. ( 17068883 )
2006
14
Erythema infectiosum. ( 16502203 )
2005
15
Incubation period for fifth disease. ( 15702058 )
2005
16
Parvovirus B19 infection: fifth disease and more. ( 15767606 )
2005
17
What you need to know about ... erythema infectiosum. ( 14768150 )
2004
18
Photo quiz. Erythema infectiosum. ( 10696555 )
2000
19
Slapped cheek is fifth disease: but what of the others? ( 11127184 )
2000
20
Erythema infectiosum (Fifth disease) and pregnancy. ( 10099795 )
1999
21
Fifth disease in a small rural community. What are the consequences? ( 10048252 )
1999
22
Neonatal erythema infectiosum. ( 9583210 )
1998
23
Human parvovirus B19--flushed in face though healthy (fifth disease and more). ( 9849265 )
1998
24
Conjunctivitis associated with fifth disease in a child: a case report. ( 9286318 )
1996
25
Index of suspicion. Case 1. Diagnosis: erythema infectiosum (EI). ( 8857202 )
1996
26
Fifth disease after immunoglobulin administration in an AIDS patient with parvovirus-induced red cell aplasia. ( 8686703 )
1996
27
Erythema infectiosum (fifth disease). ( 8559707 )
1995
28
A study by means of a new assay of the relationship between an outbreak of erythema infectiosum and non-immune hydrops fetalis caused by human parvovirus B19. ( 8586838 )
1995
29
Persistent erythema infectiosum-like rash as a prodrome of acute lymphocytic leukemia. ( 8041657 )
1994
30
What is your assessment? Erythema infectiosum. ( 7708465 )
1994
31
Erythema infectiosum and other parvovirus B19 infections. ( 8042568 )
1994
32
Case report: detection of parvovirus B19 in a skin biopsy of a patient with erythema infectiosum. ( 8083666 )
1994
33
Images in clinical medicine. Fifth disease. ( 8090166 )
1994
34
Acute polyarthritis. Fifth disease passed from child to adult. ( 8202421 )
1994
35
An outbreak of erythema infectiosum among hospital staff members including a patient with pleural fluid and pericardial effusion. ( 8335751 )
1993
36
Parvovirus B-19 infection: aplastic crisis, erythema infectiosum and idiopathic thrombocytopenic purpura. ( 1645857 )
1991
37
Human parvovirus B19 specific IgG, IgA, and IgM antibodies and DNA in serum specimens from persons with erythema infectiosum. ( 1765775 )
1991
38
Erythema infectiosum and pregnancy-related complications. ( 1846083 )
1991
39
Fifth disease and other parvovirus B19 infections. ( 1649150 )
1991
40
Aseptic meningitis with erythema infectiosum. ( 2158894 )
1990
41
American Academy of Pediatrics Committee on Infectious Diseases: Parvovirus, erythema infectiosum, and pregnancy. ( 2153280 )
1990
42
Occupational risk of human parvovirus B19 infection for school and day-care personnel during an outbreak of erythema infectiosum. ( 2157074 )
1990
43
Erythema infectiosum ('fifth disease') exposure during pregnancy. ( 2157336 )
1990
44
Erythema infectiosum and pregnancy-related complications. ( 2171743 )
1990
45
Erythema infectiosum--the fifth disease: case report. ( 2313450 )
1990
46
Prospective study of human parvovirus (B19) infection in pregnancy. Public Health Laboratory Service Working Party on Fifth Disease. ( 2161263 )
1990
47
Fifth disease: role for nurses in pediatric practice. ( 2163055 )
1990
48
Erythema infectiosum (fifth disease). ( 2538215 )
1989
49
Erythema infectiosum in a primary school: investigation of an outbreak in Bury. ( 2552489 )
1989
50
Fifth disease. A brief review of infections in childhood, in adulthood, and pregnancy. ( 2552948 )
1989

Variations for Erythema Infectiosum

Expression for Erythema Infectiosum

Search GEO for disease gene expression data for Erythema Infectiosum.

Pathways for Erythema Infectiosum

GO Terms for Erythema Infectiosum

Biological processes related to Erythema Infectiosum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell cycle GO:0007049 8.8 E2F6 LIG3 PIN1

Sources for Erythema Infectiosum

3 CDC
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10 dbSNP
11 DGIdb
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20 FMA
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35 ICD10 via Orphanet
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37 IUPHAR
38 KEGG
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45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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