MCID: ERY018
MIFTS: 10

Erythema Nodosum, Idiopathic

Categories: Rare diseases

Aliases & Classifications for Erythema Nodosum, Idiopathic

MalaCards integrated aliases for Erythema Nodosum, Idiopathic:

Name: Erythema Nodosum, Idiopathic 52 71
Erythema Nodosum of Unknown Etiology 52
Idiopathic Erythema Nodosum 52

Classifications:



External Ids:

UMLS 71 C2930919

Summaries for Erythema Nodosum, Idiopathic

NIH Rare Diseases : 52 Erythema nodosum (EN) is a skin condition in which red bumps (nodules) form on the shins. Less commonly, the nodules form on other areas of the body such as the thighs and forearms. The lesions begin as firm, hot, red, painful lumps and progress to a purplish color. EN is a type of inflammatory disorder affecting the layer of fat under the skin (panniculitis ). Other symptoms that may accompany the skin findings include the following: fever, a general feeling of being ill. joint aches, and swelling of the affected area. In many cases, EN is presumed to be a delayed reaction to antigens associated with various infections, drugs, and certain systemic diseases. In some cases, however, EN has no identifiable cause (idiopathic); in these cases, clinical follow-up is needed to rule out certain conditions including inflammatory bowel disease , sarcoidosis , lymphoma , and Behcet's disease . Treatment may include rest, nonsteroidal anti-inflammatory drugs (NSAIDS), steroids, hot or cold compresses, potassium iodide solution, and supportive bandages or compression stockings . Symptoms usually resolve within six weeks, but EN may become a chronic disorder lasting for months and, occasionally, for years. Approximately 30% cases of idiopathic EN may last more than 6 months.

MalaCards based summary : Erythema Nodosum, Idiopathic, also known as erythema nodosum of unknown etiology, is related to granulomatous mastitis and mastitis. Affiliated tissues include skin.

Related Diseases for Erythema Nodosum, Idiopathic

Diseases related to Erythema Nodosum, Idiopathic via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 granulomatous mastitis 10.3
2 mastitis 10.2
3 autoimmune disease 10.0
4 sarcoidosis 1 10.0
5 thrombocytosis 10.0
6 breast disease 10.0
7 lymphopenia 10.0
8 reactive arthritis 10.0

Graphical network of the top 20 diseases related to Erythema Nodosum, Idiopathic:



Diseases related to Erythema Nodosum, Idiopathic

Symptoms & Phenotypes for Erythema Nodosum, Idiopathic

Drugs & Therapeutics for Erythema Nodosum, Idiopathic

Search Clinical Trials , NIH Clinical Center for Erythema Nodosum, Idiopathic

Genetic Tests for Erythema Nodosum, Idiopathic

Anatomical Context for Erythema Nodosum, Idiopathic

MalaCards organs/tissues related to Erythema Nodosum, Idiopathic:

40
Skin

Publications for Erythema Nodosum, Idiopathic

Articles related to Erythema Nodosum, Idiopathic:

# Title Authors PMID Year
1
Exploring the combination of SSKI and topical heparin in a case of erythema nodosum migrans. 61
29644775 2018
2
An Unusual Cause of Oligoarthritis and Erythema Nodosum: Idiopathic Granulomatous Mastitis. 61
30375541 2017
3
Erythema nodosum migrans successfully treated with indomethacin: A rare entity. 61
25625103 2014
4
Are clinical features in Löfgren's syndrome-related erythema nodosum different from idiopathic erythema nodosum? 61
23461075 2012
5
Case reports: nodular vasculitis responsive to mycophenolate mofetil. 61
17373149 2006
6
Erythema nodosum and antitubercular therapy. 61
15764034 2004
7
[Erythema nodosum: 112 cases. Epidemiology, clinical aspects and histopathology]. 61
9324739 1997
8
Erythema nodosum-arthopathy complex as an initial presentation of Behçet's disease. Report of five cases. 61
671441 1978

Variations for Erythema Nodosum, Idiopathic

Expression for Erythema Nodosum, Idiopathic

Search GEO for disease gene expression data for Erythema Nodosum, Idiopathic.

Pathways for Erythema Nodosum, Idiopathic

GO Terms for Erythema Nodosum, Idiopathic

Sources for Erythema Nodosum, Idiopathic

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56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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