Aliases & Classifications for Erythroplakia

MalaCards integrated aliases for Erythroplakia:

Name: Erythroplakia 54
Erythroplasia 74

Classifications:



External Ids:

UMLS 74 C0014818

Summaries for Erythroplakia

MalaCards based summary : Erythroplakia, also known as erythroplasia, is related to leukoplakia and oral cancer. An important gene associated with Erythroplakia is BMI1 (BMI1 Proto-Oncogene, Polycomb Ring Finger), and among its related pathways/superpathways are Glucose / Energy Metabolism and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Metformin and Hypoglycemic Agents have been mentioned in the context of this disorder. Affiliated tissues include salivary gland.

Wikipedia : 77 Erythroplakia (or erythroplasia) is a clinical term to describe any erythematous (red) area on a mucous... more...

Related Diseases for Erythroplakia

Diseases related to Erythroplakia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 leukoplakia 10.5
2 oral cancer 10.3
3 lichen planus 10.2
4 oral leukoplakia 10.2
5 oral lichen planus 10.2
6 fanconi anemia, complementation group a 10.0
7 graft-versus-host disease 10.0
8 in situ carcinoma 10.0
9 chronic graft versus host disease 10.0
10 hematologic cancer 9.8 ABCG2 BMI1
11 brain cancer 9.6 ABCG2 BMI1
12 large intestine cancer 9.6 ABCG2 ALDH1A1

Graphical network of the top 20 diseases related to Erythroplakia:



Diseases related to Erythroplakia

Symptoms & Phenotypes for Erythroplakia

Drugs & Therapeutics for Erythroplakia

Drugs for Erythroplakia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 3,Phase 2 657-24-9 14219 4091
2 Hypoglycemic Agents Phase 3,Phase 2
3
Aminolevulinic acid Approved Phase 1, Phase 2 106-60-5 137
4
Pioglitazone Approved, Investigational Phase 2 111025-46-8 4829
5 Dermatologic Agents Phase 1, Phase 2,Not Applicable
6 Pharmaceutical Solutions Phase 1, Phase 2
7 Photosensitizing Agents Phase 1, Phase 2,Not Applicable
8
Trioxsalen Approved Not Applicable 3902-71-4 5585
9
Serine Approved, Nutraceutical 56-45-1 5951
10 Serpins
11 HIV Protease Inhibitors
12
protease inhibitors
13 Squamous cell carcinoma-related antigen
14
Diadenosine tetraphosphate 5542-28-9 21706
15 Serine Proteinase Inhibitors
16 Platelet Aggregation Inhibitors
17 Hematoporphyrin Derivative Not Applicable
18 Dihematoporphyrin Ether Not Applicable
19 Ether Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions Recruiting NCT03685409 Phase 3 Metformin Hydrochloride 500 MG;Placebo Oral Tablet
2 Treatment of Oral Premalignant Lesions With 5-ALA PDT Completed NCT00571974 Phase 1, Phase 2 5-Aminolevulinic Acid (Levulan KerastickTM)
3 Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion Active, not recruiting NCT02581137 Phase 2 Metformin Hydrochloride
4 Pioglitazone for Oral Premalignant Lesions Terminated NCT00951379 Phase 2 Pioglitazone hydrochloride
5 Natural History of Oro-pharyngeal Cancer Precursors Completed NCT00179361
6 Salivary and Serum Levels of Chemerin and MMP-9 in Oral Premalignant and Malignant Lesions Completed NCT02323672
7 The Oral Microbiome as a Prognostic Tool in Oral Malignant and Premalignant Lesions and in Medication Related Osteonecrosis of the Jaw Recruiting NCT03418454
8 Fluorescence & Reflectance Imaging to Detect Oral Neoplasia Recruiting NCT00542373 Not Applicable
9 Salivary Ap4A, SCCA, TROP2 in Oral Cancer Patients Active, not recruiting NCT03529604
10 Photodynamic Therapy Using Porfimer Sodium in Treating Patients With Recurrent Mouth or Throat Dysplasia or Recurrent In Situ Cancer or Stage I Cancer of the Mouth or Throat Terminated NCT00530088 Not Applicable porfimer sodium;Photdynamic Therapy (PDT)

Search NIH Clinical Center for Erythroplakia

Genetic Tests for Erythroplakia

Anatomical Context for Erythroplakia

MalaCards organs/tissues related to Erythroplakia:

42
Salivary Gland

Publications for Erythroplakia

Articles related to Erythroplakia:

(show top 50) (show all 121)
# Title Authors Year
1
Oral erythroplakia-What is it? ( 29480616 )
2018
2
Bibliometric analysis of a century of research on oral erythroplakia and leukoplakia. ( 29344996 )
2018
3
Accuracy of dermoscopy in distinguishing erythroplasia of Queyrat from common forms of chronic balanitis: results from a multicentric observational study. ( 30468529 )
2018
4
Dermatoscopic findings of penile intraepithelial neoplasia: Bowenoid papulosis, Bowen disease and erythroplasia of Queyrat. ( 30585302 )
2018
5
Development of squamous cell carcinoma from erythroplasia of Queyrat following photodynamic therapy. ( 29888705 )
2018
6
A plea to provide best evidence in trials under sample-size restrictions: the example of pioglitazone to resolve leukoplakia and erythroplakia in Fanconi anemia patients. ( 28545482 )
2017
7
Oral verruciform xanthoma and erythroplakia associated with chronic graft-versus-host disease: a rare case report and review of the literature. ( 29183344 )
2017
8
A case of erythroplasia of Queyrat successfully treated with combination carbon dioxide laser vaporization and surgery. ( 25475424 )
2016
9
Erythroplasia of Queyrat treated by laser and light modalities: a systematic review. ( 27324019 )
2016
10
Erythroplasia of Queyrat treated with methyl aminolevulinate-photodynamic therapy (MAL-PDT): case report and review of the literature. ( 27905695 )
2016
11
Erythroplasia of Queyrat treated with topical 5-fluorouracil. ( 28300890 )
2016
12
Outcome of excision of oral erythroplakia. ( 25467247 )
2015
13
Clinical characteristics of narrow-band imaging of oral erythroplakia and its correlation with pathology. ( 25975717 )
2015
14
Two cases of erythroplasia of Queyrat with persistent post-treatment inflammation after histological remission of epithelial dysplasia. ( 26105658 )
2015
15
Penile preservation surgery in a case of erythroplasia of Queyrat involving the glans penis and distal urethra. ( 23675865 )
2014
16
Optical coherence tomography imaging of erythroplasia of Queyrat and treatment with imiquimod 5% cream: a case report. ( 24135797 )
2014
17
Queyrat erythroplasia accompanied by bladder cancer in a circumcised male. ( 24927357 )
2014
18
Expression of cancer stem cell markers ALDH1 and Bmi1 in oral erythroplakia and the risk of oral cancer. ( 22725270 )
2013
19
Leukoplakia and erythroplakia of the oral mucosa--a brief overview. ( 23957095 )
2012
20
Expression of podoplanin and ABCG2 in oral erythroplakia correlate with oral cancer development. ( 22525603 )
2012
21
Methyl-aminolevulinate photodynamic therapy for the treatment of erythroplasia of Queyrat in 23 patients. ( 21888568 )
2012
22
Erythroplasia of Queyrat refractory to photodynamic therapy. ( 22831651 )
2012
23
Erythroplasia of queyrat. ( 24765462 )
2012
24
Oral cancer and oral erythroplakia: an update and implication for clinicians. ( 21884139 )
2011
25
Use of narrow band imaging guidance in the management of oral erythroplakia. ( 21036438 )
2011
26
Methylaminolaevulinic acid photodynamic therapy in the treatment of erythroplasia of Queyrat. ( 21849768 )
2011
27
Absence of PCR-detectable human papilloma virus in erythroplasia of Queyrat using a comparative control group. ( 20444743 )
2010
28
Oral erythroplakia and speckled leukoplakia: retrospective analysis of 13 cases. ( 19575119 )
2009
29
A case of erythroplasia of queyrat treated with imiquimod 5% cream and excision. ( 20523838 )
2009
30
Oral pathology: erythroplakia. ( 19326610 )
2008
31
A clinicopathologic study of oral leukoplakia and erythroplakia in a Thai population. ( 17823667 )
2007
32
Erythroplasia of Queyrat treated with imiquimod 5% cream. ( 17052503 )
2006
33
Oral erythroplakia--a review. ( 15975518 )
2005
34
Erythroplasia of Queyrat treated with topical methyl aminolevulinate photodynamic therapy. ( 16008656 )
2005
35
Carbon dioxide laser treatment of erythroplasia of Queyrat: a revisited treatment to this condition. ( 16164731 )
2005
36
Erythroplasia of Queyrat with urethral involvement: treatment with carbon dioxide laser vaporization. ( 16416620 )
2005
37
Treatment of Bowen's disease and erythroplasia of Queyrat. ( 14616349 )
2003
38
Imiquimod 5% cream in the treatment of human papillomavirus-16-positive erythroplasia of Queyrat. ( 12145439 )
2002
39
Topical cidofovir for erythroplasia of Queyrat of the glans penis. ( 12174131 )
2002
40
Chewing tobacco, alcohol, and the risk of erythroplakia. ( 10919731 )
2000
41
Erythroplasia of queyrat treated by topical aminolaevulinic acid photodynamic therapy: a cautionary tale. ( 10792247 )
2000
42
Experimental intervention study about recognition of erythroplakia by undergraduate dental students. ( 10858764 )
1999
43
A high prevalence of p53 mutations in pre-malignant oral erythroplakia. ( 9935172 )
1999
44
Erythroplasia of Queyrat treated by topical aminolaevulinic acid photodynamic therapy. ( 10233277 )
1999
45
The detection of human papillomavirus 16 DNA in erythroplasia of Queyrat invading the urethra. ( 9536246 )
1998
46
Urology image quiz. Erythroplasia of Queyrat. ( 8732219 )
1996
47
Erythroplakia: the dangerous red mucosa. ( 9002888 )
1995
48
Oral leukoplakia and erythroplakia: a review and update. ( 7833463 )
1994
49
Erythroplasia of Queyrat treated with isotretinoin. ( 8105246 )
1993
50
Carcinoma in situ of penis. Is distinction between erythroplasia of Queyrat and Bowen's disease relevant? ( 2247911 )
1990

Variations for Erythroplakia

Expression for Erythroplakia

Search GEO for disease gene expression data for Erythroplakia.

Pathways for Erythroplakia

Pathways related to Erythroplakia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.45 ABCG2 ALDH1A1
2 10.52 ABCG2 BMI1

GO Terms for Erythroplakia

Sources for Erythroplakia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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