MCID: ESP012
MIFTS: 24

Esophageal Adenoid Cystic Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Esophageal Adenoid Cystic Carcinoma

MalaCards integrated aliases for Esophageal Adenoid Cystic Carcinoma:

Name: Esophageal Adenoid Cystic Carcinoma 12 15 71
Adenoid Cystic Carcinoma, Esophagus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4878
NCIt 50 C5342
UMLS 71 C1333441

Summaries for Esophageal Adenoid Cystic Carcinoma

Disease Ontology : 12 An esophageal carcinoma that derives from epithelial cells of the salivary gland.

MalaCards based summary : Esophageal Adenoid Cystic Carcinoma, also known as adenoid cystic carcinoma, esophagus, is related to adenoid cystic carcinoma and eccrine porocarcinoma, and has symptoms including pain An important gene associated with Esophageal Adenoid Cystic Carcinoma is PHLDA2 (Pleckstrin Homology Like Domain Family A Member 2), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include salivary gland.

Related Diseases for Esophageal Adenoid Cystic Carcinoma

Diseases related to Esophageal Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 343)
# Related Disease Score Top Affiliating Genes
1 adenoid cystic carcinoma 29.9 VIM NCAM1 KIT
2 eccrine porocarcinoma 10.3 VIM CEACAM5
3 nodular hidradenoma 10.3 VIM CEACAM5
4 hidradenoma 10.3 VIM CEACAM5
5 gallbladder papillary carcinoma 10.3 PDPN CEACAM5
6 ovarian mucinous cystadenocarcinoma 10.3 VIM CEACAM5
7 chondroid chordoma 10.3 VIM CEACAM5
8 vaginal glandular tumor 10.3 CHGA CEACAM5
9 xanthogranulomatous cholecystitis 10.3 PDPN CEACAM5
10 eccrine papillary adenocarcinoma 10.3 PDPN CEACAM5
11 female urethral cancer 10.2 CHGA CEACAM5
12 pancreatic serous cystadenoma 10.2 CHGA CEACAM5
13 lymphangitis 10.2 PDPN CEACAM5
14 secretory meningioma 10.2 VIM CEACAM5
15 appendiceal neoplasm 10.2 CHGA CEACAM5
16 liver lipoma 10.2 CEACAM5 AFP
17 mucinous adenofibroma 10.2 SYP CEACAM5
18 gestational ovarian choriocarcinoma 10.2 CEACAM5 AFP
19 immature teratoma of ovary 10.2 CEACAM5 AFP
20 syringoma 10.2 VIM CEACAM5
21 urachal adenocarcinoma 10.2 CEACAM5 AFP
22 vulva basal cell carcinoma 10.2 SYP CEACAM5
23 liver inflammatory pseudotumor 10.2 CEACAM5 AFP
24 large intestine lipoma 10.2 CHGA CEACAM5
25 clear cell basal cell carcinoma 10.2 CHGA CEACAM5
26 rectum signet ring adenocarcinoma 10.2 CEACAM5 AFP
27 intracystic papillary adenoma 10.2 CHGA CEACAM5
28 glomangioma 10.2 VIM SYP
29 lipoma of colon 10.2 CHGA CEACAM5
30 ewing sarcoma of bone 10.2 VIM CHGA
31 eccrine papillary adenoma 10.2 PDPN CEACAM5
32 dermoid cyst of ovary 10.2 CEACAM5 AFP
33 renal pelvis adenocarcinoma 10.2 CEACAM5 AFP
34 bile duct cystadenocarcinoma 10.2 CEACAM5 AFP
35 krukenberg carcinoma 10.2 SYP CEACAM5
36 papillary squamous carcinoma 10.2 SYP CEACAM5
37 parachordoma 10.2 VIM CHGA
38 nodular tenosynovitis 10.2 VIM PDPN
39 thymus lipoma 10.2 ANO1 AFP
40 immune system organ benign neoplasm 10.2 ANO1 AFP
41 liver sarcoma 10.2 CEACAM5 AFP
42 glomangiomyoma 10.2 VIM SYP
43 papillary tumor of the pineal region 10.2 VIM SYP
44 angiocentric glioma 10.2 VIM SYP
45 common bile duct disease 10.2 CEACAM5 AFP
46 abdominal tuberculosis 10.2 CEACAM5 AFP
47 bile duct cysts 10.2 CEACAM5 AFP
48 keratinizing squamous cell carcinoma 10.2 SYP CEACAM5
49 cystic basal cell carcinoma 10.2 SYP CEACAM5
50 ovarian benign neoplasm 10.2 CEACAM5 AFP

Graphical network of the top 20 diseases related to Esophageal Adenoid Cystic Carcinoma:



Diseases related to Esophageal Adenoid Cystic Carcinoma

Symptoms & Phenotypes for Esophageal Adenoid Cystic Carcinoma

UMLS symptoms related to Esophageal Adenoid Cystic Carcinoma:


pain

Drugs & Therapeutics for Esophageal Adenoid Cystic Carcinoma

Search Clinical Trials , NIH Clinical Center for Esophageal Adenoid Cystic Carcinoma

Genetic Tests for Esophageal Adenoid Cystic Carcinoma

Anatomical Context for Esophageal Adenoid Cystic Carcinoma

MalaCards organs/tissues related to Esophageal Adenoid Cystic Carcinoma:

40
Salivary Gland

Publications for Esophageal Adenoid Cystic Carcinoma

Articles related to Esophageal Adenoid Cystic Carcinoma:

# Title Authors PMID Year
1
Endoscopic submucosal dissection in a patient with esophageal adenoid cystic carcinoma. 61
29259386 2017
2
A case of adenoid cystic carcinoma of the esophagus. 61
26943443 2015
3
Response to oxaliplatin with cetuximab in minor salivary gland adenoid cystic carcinoma. 61
19688981 2009
4
Primary esophageal adenoid cystic carcinoma. 61
20485637 2007
5
Primary adenoid cystic carcinoma of the esophagus. Report of a case and its histochemical characterization. 61
3028038 1986
6
Adenoid cystic carcinoma of the esophagus. Complete response to combination chemotherapy. 61
3004692 1986

Variations for Esophageal Adenoid Cystic Carcinoma

Expression for Esophageal Adenoid Cystic Carcinoma

Search GEO for disease gene expression data for Esophageal Adenoid Cystic Carcinoma.

Pathways for Esophageal Adenoid Cystic Carcinoma

GO Terms for Esophageal Adenoid Cystic Carcinoma

Biological processes related to Esophageal Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mast cell degranulation GO:0043303 9.16 CHGA KIT
2 mast cell chemotaxis GO:0002551 8.96 CHGA KIT
3 mast cell cytokine production GO:0032762 8.62 CHGA KIT

Sources for Esophageal Adenoid Cystic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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