MCID: ESP006
MIFTS: 24

Esophageal Adenosquamous Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Esophageal Adenosquamous Carcinoma

MalaCards integrated aliases for Esophageal Adenosquamous Carcinoma:

Name: Esophageal Adenosquamous Carcinoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5625
NCIt 50 C27421
UMLS 73 C2063886

Summaries for Esophageal Adenosquamous Carcinoma

Disease Ontology : 12 An esophageal carcinoma that derives from squamous cells and gland-like cells.

MalaCards based summary : Esophageal Adenosquamous Carcinoma is related to adenosquamous carcinoma and mucoepidermoid esophageal carcinoma. An important gene associated with Esophageal Adenosquamous Carcinoma is WWOX (WW Domain Containing Oxidoreductase), and among its related pathways/superpathways are Adhesion and G12-G13 in Cellular Signaling. Affiliated tissues include kidney, colon and breast, and related phenotype is no phenotypic analysis.

Related Diseases for Esophageal Adenosquamous Carcinoma

Diseases related to Esophageal Adenosquamous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 adenosquamous carcinoma 10.2
2 mucoepidermoid esophageal carcinoma 10.1 CEACAM5 WWOX
3 malignant acrospiroma 10.1 CEACAM5 KRT5
4 malignant spiradenoma 10.1 CEACAM5 KRT5
5 bile duct mucoepidermoid carcinoma 10.1 CEACAM5 KRT5
6 malignant biphasic mesothelioma 10.1 CEACAM5 KRT5
7 prostate squamous cell carcinoma 10.1 CEACAM5 KRT5
8 alveolar periostitis 10.0 JUN WWOX
9 esophageal disease 10.0 CEACAM5 WWOX
10 meibomian cyst 10.0 CEACAM5 JUN
11 squamous cell carcinoma 10.0
12 adenoid squamous cell carcinoma 10.0
13 large cell carcinoma 10.0 CEACAM5 KRT5
14 gastric cardia carcinoma 10.0 CDH1 WWOX
15 breast cystic hypersecretory carcinoma 10.0 CDH1 KRT5
16 gastric signet ring cell adenocarcinoma 9.9 CDH1 CEACAM5
17 lymphoepithelioma-like carcinoma 9.9 CDH1 KRT5
18 infiltrative basal cell carcinoma 9.9 CDH1 CEACAM5
19 chondroid chordoma 9.9 CDH1 CEACAM5
20 lipid-rich carcinoma 9.9 CDH1 KRT5
21 tonsil cancer 9.9 CDH1 KRT5
22 pre-malignant neoplasm 9.9 CDH1 KRT5
23 papillary adenocarcinoma 9.9 CDH1 CEACAM5
24 bile duct adenocarcinoma 9.9 CDH1 CEACAM5
25 oropharynx cancer 9.9 CDH1 KRT5
26 in situ carcinoma 9.9 CDH1 KRT5
27 spindle cell carcinoma 9.9 CDH1 KRT5
28 ovarian cancer 1 9.9 CDH1 CEACAM5
29 malignant ovarian surface epithelial-stromal neoplasm 9.9 CDH1 CEACAM5
30 ovary epithelial cancer 9.9 CDH1 CEACAM5
31 ductal carcinoma in situ 9.9 CDH1 KRT5
32 colonic disease 9.9 CDH1 CEACAM5
33 colorectal adenocarcinoma 9.9 CDH1 CEACAM5
34 respiratory system cancer 9.9 CDH1 CEACAM5
35 intestinal disease 9.8 CDH1 CEACAM5
36 respiratory system disease 9.8 CDH1 CEACAM5
37 endocrine gland cancer 9.8 CDH1 CEACAM5
38 pancreas adenocarcinoma 9.8 CDH1 CEACAM5
39 stomach disease 9.8 CDH1 CEACAM5 WWOX
40 gastrointestinal system cancer 9.8 CDH1 CEACAM5 WWOX
41 gastrointestinal system disease 9.8 CDH1 CEACAM5 WWOX
42 breast adenomyoepithelioma 9.8 CDH1 CEACAM5 KRT5
43 breast myoepithelial neoplasm 9.8 CDH1 CEACAM5 KRT5
44 colon adenocarcinoma 9.7 CDH1 CEACAM5 JUN
45 autosomal dominant polycystic kidney disease 9.7 CDH1 JUN
46 large intestine cancer 9.7 CDH1 CEACAM5 JUN
47 gastric adenocarcinoma 9.7 CDH1 CEACAM5 JUN
48 lung cancer susceptibility 3 9.7 CDH1 CEACAM5 JUN
49 gallbladder cancer 9.7 CDH1 CEACAM5
50 esophageal cancer 9.5 CDH1 CEACAM5 JUN WWOX

Graphical network of the top 20 diseases related to Esophageal Adenosquamous Carcinoma:



Diseases related to Esophageal Adenosquamous Carcinoma

Symptoms & Phenotypes for Esophageal Adenosquamous Carcinoma

MGI Mouse Phenotypes related to Esophageal Adenosquamous Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 8.92 CDH1 JUN KRT5 WWOX

Drugs & Therapeutics for Esophageal Adenosquamous Carcinoma

Search Clinical Trials , NIH Clinical Center for Esophageal Adenosquamous Carcinoma

Genetic Tests for Esophageal Adenosquamous Carcinoma

Anatomical Context for Esophageal Adenosquamous Carcinoma

MalaCards organs/tissues related to Esophageal Adenosquamous Carcinoma:

41
Kidney, Colon, Breast, Ovary, Tonsil, Prostate, Pancreas

Publications for Esophageal Adenosquamous Carcinoma

Articles related to Esophageal Adenosquamous Carcinoma:

# Title Authors Year
1
Esophageal adenosquamous carcinoma mimicking acantholytic squamous cell carcinoma. ( 29085501 )
2017
2
Primary esophageal adenosquamous carcinoma: a retrospective analysis of 24 cases. ( 24127755 )
2013
3
Esophageal adenosquamous carcinoma in a cat. ( 11217072 )
2001

Variations for Esophageal Adenosquamous Carcinoma

Expression for Esophageal Adenosquamous Carcinoma

Search GEO for disease gene expression data for Esophageal Adenosquamous Carcinoma.

Pathways for Esophageal Adenosquamous Carcinoma

Pathways related to Esophageal Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.41 CDH1 CEACAM5
2 11.35 CDH1 JUN
3 11.07 JUN KRT5
4 10.85 CDH1 JUN
5 10.3 CDH1 JUN

GO Terms for Esophageal Adenosquamous Carcinoma

Biological processes related to Esophageal Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to organic substance GO:0010033 8.62 CDH1 JUN

Sources for Esophageal Adenosquamous Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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