MCID: ESP010
MIFTS: 30

Esophageal Basaloid Squamous Cell Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Esophageal Basaloid Squamous Cell Carcinoma

MalaCards integrated aliases for Esophageal Basaloid Squamous Cell Carcinoma:

Name: Esophageal Basaloid Squamous Cell Carcinoma 12 15
Basaloid Squamous Carcinoma of Esophagus 12
Esophageal Basaloid Carcinoma 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7051
NCIt 50 C7032
UMLS 70 C1333443

Summaries for Esophageal Basaloid Squamous Cell Carcinoma

MalaCards based summary : Esophageal Basaloid Squamous Cell Carcinoma, also known as basaloid squamous carcinoma of esophagus, is related to basaloid squamous cell carcinoma and squamous cell carcinoma, and has symptoms including pain and regurgitation. An important gene associated with Esophageal Basaloid Squamous Cell Carcinoma is SFRP2 (Secreted Frizzled Related Protein 2), and among its related pathways/superpathways are Human cytomegalovirus infection and Pathways in cancer. Affiliated tissues include breast, lung and skin, and related phenotypes are cellular and craniofacial

Related Diseases for Esophageal Basaloid Squamous Cell Carcinoma

Diseases related to Esophageal Basaloid Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 135)
# Related Disease Score Top Affiliating Genes
1 basaloid squamous cell carcinoma 30.4 TP53 KRT14 EGFR
2 squamous cell carcinoma 10.6
3 esophageal cancer 10.2
4 b-cell lymphoma 10.2
5 dysphagia 10.2
6 esophagus verrucous carcinoma 10.0 TP53 EGFR
7 verrucous carcinoma 10.0 TP53 EGFR
8 frontal lobe neoplasm 10.0 TP53 EGFR
9 basosquamous carcinoma 10.0 TP53 PTGER4
10 spinal cord oligodendroglioma 10.0 TP53 EGFR
11 eccrine sweat gland cancer 10.0 TP53 PTGER4
12 soft tissue sarcoma 10.0 TP53 EGFR
13 breast malignant phyllodes tumor 10.0 TP53 EGFR
14 supraglottis cancer 10.0 TP53 EGFR
15 mammary analogue secretory carcinoma 10.0 TP53 EGFR
16 adenosquamous carcinoma 10.0 TP53 EGFR
17 keratinizing squamous cell carcinoma 10.0 TP53 EGFR
18 peritoneal serous adenocarcinoma 10.0 TP53 PTGER4
19 primary peritoneal carcinoma 10.0 TP53 EGFR
20 malignant spiradenoma 10.0 TP53 PTGER4
21 mixed glioma 10.0 TP53 EGFR
22 vulva squamous cell carcinoma 10.0 TP53 EGFR
23 bone squamous cell carcinoma 10.0 TP53 EGFR
24 microglandular adenosis 10.0 TP53 EGFR
25 laryngeal benign neoplasm 10.0 TP53 EGFR
26 vulvar disease 10.0 TP53 EGFR
27 high grade ependymoma 10.0 TP53 EGFR
28 cerebral ventricle cancer 10.0 TP53 EGFR
29 anus cancer 10.0 TP53 EGFR
30 cerebrum cancer 10.0 TP53 EGFR
31 hypopharynx cancer 10.0 TP53 EGFR
32 supratentorial cancer 10.0 TP53 EGFR
33 uterine body mixed cancer 10.0 TP53 EGFR
34 gliomatosis cerebri 10.0 TP53 EGFR
35 brain stem glioma 10.0 TP53 EGFR
36 penile disease 10.0 TP53 EGFR
37 inverted papilloma 10.0 TP53 EGFR
38 mixed cell type cancer 10.0 TP53 EGFR
39 respiratory system benign neoplasm 10.0 TP53 EGFR
40 pulmonary blastoma 10.0 TP53 EGFR
41 gallbladder adenocarcinoma 10.0 TP53 EGFR
42 diffuse astrocytoma 10.0 TP53 EGFR
43 lung adenoma 10.0 TP53 EGFR
44 esophagus adenocarcinoma 10.0 TP53 EGFR
45 rectum adenocarcinoma 10.0 TP53 EGFR
46 muir-torre syndrome 10.0 TP53 PTGER4
47 anus disease 10.0 TP53 EGFR
48 lip and oral cavity cancer 10.0 TP53 EGFR
49 ovarian cystadenocarcinoma 10.0 TP53 EGFR
50 vulva cancer 10.0 TP53 EGFR

Graphical network of the top 20 diseases related to Esophageal Basaloid Squamous Cell Carcinoma:



Diseases related to Esophageal Basaloid Squamous Cell Carcinoma

Symptoms & Phenotypes for Esophageal Basaloid Squamous Cell Carcinoma

UMLS symptoms related to Esophageal Basaloid Squamous Cell Carcinoma:


pain; regurgitation

MGI Mouse Phenotypes related to Esophageal Basaloid Squamous Cell Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.77 EGFR KRT14 PTGER4 SFRP2 TP53
2 craniofacial MP:0005382 9.62 EGFR KRT14 SFRP2 TP53
3 muscle MP:0005369 9.56 EGFR PTGER4 SFRP2 TP53
4 neoplasm MP:0002006 9.46 EGFR KRT14 PTGER4 TP53
5 pigmentation MP:0001186 9.13 EGFR KRT14 TP53
6 respiratory system MP:0005388 8.92 EGFR KRT14 PTGER4 TP53

Drugs & Therapeutics for Esophageal Basaloid Squamous Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Esophageal Basaloid Squamous Cell Carcinoma

Genetic Tests for Esophageal Basaloid Squamous Cell Carcinoma

Anatomical Context for Esophageal Basaloid Squamous Cell Carcinoma

MalaCards organs/tissues related to Esophageal Basaloid Squamous Cell Carcinoma:

40
Breast, Lung, Skin, Thymus, Brain, Neutrophil, Bone

Publications for Esophageal Basaloid Squamous Cell Carcinoma

Articles related to Esophageal Basaloid Squamous Cell Carcinoma:

(show all 15)
# Title Authors PMID Year
1
Cutaneous metastasis from esophageal basaloid squamous cell carcinoma: A case report. 61
33596520 2021
2
Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy. 61
32757102 2020
3
Subcutaneous metastasis from recurrent basaloid squamous cell carcinoma of the esophagus. 61
29078709 2019
4
A long-surviving patient with advanced esophageal basaloid squamous cell carcinoma treated only with radiotherapy: case report and literature review. 61
29216832 2017
5
[Two Resected Cases with Superficial Basaloid Squamous Carcinoma of the Esophagus]. 61
27899779 2016
6
The Preoperative Neutrophil-To-Lymphocyte Ratio Is a Novel Immune Parameter for the Prognosis of Esophageal Basaloid Squamous Cell Carcinoma. 61
27959959 2016
7
Molecular pathology and potential therapeutic targets in esophageal basaloid squamous cell carcinoma. 61
26045734 2015
8
[A case of superficial esophageal basaloid squamous cell carcinoma resected by endoscopic submucosal dissection]. 61
24898489 2014
9
Downregulation of sFRP-2 by epigenetic silencing activates the β-catenin/Wnt signaling pathway in esophageal basaloid squamous cell carcinoma. 61
24464051 2014
10
Immunohistochemical and oncogenetic analyses of the esophageal basaloid squamous cell carcinoma in comparison with conventional squamous cell carcinomas. 61
22607702 2012
11
[Diagnosis and treatment of basaloid squamous cell carcinoma of the esophagus]. 61
18953844 2008
12
A case of leptomeningeal carcinomatosis from esophageal basaloid carcinoma diagnosed by quantitative reverse transcription-polymerase chain reaction for carcinoembryonic antigen. 61
15692794 2005
13
Esophageal basaloid carcinoma with marked myoepithelial differentiation. 61
12031088 2002
14
An isolated digital metastasis of esophageal basaloid squamous cell carcinoma. 61
10885705 2000
15
[A case of subtotal esophagectomy for esophageal basaloid carcinoma after mitral valve replacement]. 61
8288936 1993

Variations for Esophageal Basaloid Squamous Cell Carcinoma

Expression for Esophageal Basaloid Squamous Cell Carcinoma

Search GEO for disease gene expression data for Esophageal Basaloid Squamous Cell Carcinoma.

Pathways for Esophageal Basaloid Squamous Cell Carcinoma

GO Terms for Esophageal Basaloid Squamous Cell Carcinoma

Biological processes related to Esophageal Basaloid Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of inflammatory response GO:0050729 9.46 PTGER4 EGFR
2 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.43 SFRP2 EGFR
3 positive regulation of cell growth GO:0030307 9.4 SFRP2 EGFR
4 circadian rhythm GO:0007623 9.37 TP53 EGFR
5 cellular response to mechanical stimulus GO:0071260 9.32 PTGER4 EGFR
6 cellular response to drug GO:0035690 9.26 TP53 EGFR
7 somitogenesis GO:0001756 9.16 TP53 SFRP2
8 negative regulation of mitotic cell cycle GO:0045930 8.96 TP53 EGFR
9 positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800 8.62 TP53 EGFR

Molecular functions related to Esophageal Basaloid Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein phosphatase binding GO:0019903 8.62 TP53 EGFR

Sources for Esophageal Basaloid Squamous Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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