MCID: ESP018
MIFTS: 45

Esophageal Candidiasis

Categories: Gastrointestinal diseases, Immune diseases, Infectious diseases

Aliases & Classifications for Esophageal Candidiasis

MalaCards integrated aliases for Esophageal Candidiasis:

Name: Esophageal Candidiasis 12 3 15
Candidiasis of the Esophagus 12 73
Esophageal Moniliasis 12
Candidal Esophagitis 12
Candida Esophagitis 12
Esophageal Thrush 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13146
ICD10 33 B37.81
ICD9CM 35 112.84
NCIt 50 C27027
SNOMED-CT 68 20639004
UMLS 73 C0239295

Summaries for Esophageal Candidiasis

CDC : 3 Candidiasis is an infection caused by a yeast (a type of fungus) called Candida. Candida normally lives in the digestive tract and on skin without causing any problems.1 Sometimes, Candida can multiply and cause an infection if the environment inside the mouth, throat, or esophagus changes in a way that encourages fungal growth.

MalaCards based summary : Esophageal Candidiasis, also known as candidiasis of the esophagus, is related to laryngitis and esophagitis, eosinophilic, 1. An important gene associated with Esophageal Candidiasis is ATP12A (ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit), and among its related pathways/superpathways are Drug metabolism - cytochrome P450 and Linoleic acid metabolism. The drugs Caspofungin and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and liver.

Disease Ontology : 12 A candidiasis that involves fungal infection of the esophagus by Candida albicans in immunocompromised people, resulting in lesions, bleeding, painful swallowing and substernal pain.

Wikipedia : 76 Esophageal candidiasis is an opportunistic infection of the esophagus by Candida albicans. The disease... more...

Related Diseases for Esophageal Candidiasis

Diseases related to Esophageal Candidiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 104)
# Related Disease Score Top Affiliating Genes
1 laryngitis 30.2 ATP12A ATP4A
2 esophagitis, eosinophilic, 1 30.1 ATP12A ATP4A
3 esophageal varix 30.0 ATP12A ATP4A
4 peptic esophagitis 29.7 ATP12A ATP4A CYP2C19
5 candidiasis 10.9
6 human immunodeficiency virus infectious disease 10.2
7 acquired immunodeficiency syndrome 10.2
8 fungal esophagitis 10.2 ATP12A ATP4A
9 diclofenac allergy 10.2 ATP12A ATP4A
10 gastroduodenal crohn's disease 10.2 ATP12A ATP4A
11 neonatal candidiasis 10.2 ATP12A ATP4A
12 photoallergic dermatitis 10.2 ATP12A ATP4A
13 squamous papillomatosis 10.2 ATP12A ATP4A
14 toxic megacolon 10.2 ATP12A ATP4A
15 aspiration pneumonitis 10.2 ATP12A ATP4A
16 gastrointestinal neuroendocrine benign tumor 10.2 ATP12A ATP4A
17 gastric antral vascular ectasia 10.2 ATP12A ATP4A
18 granulomatous gastritis 10.2 ATP12A ATP4A
19 gastric neuroendocrine neoplasm 10.2 ATP12A ATP4A
20 acute laryngitis 10.2 ATP12A ATP4A
21 duodenitis 10.2 ATP12A ATP4A
22 rumination disorder 10.2 ATP12A ATP4A
23 active peptic ulcer disease 10.2 ATP12A ATP4A
24 congenital disorder of deglycosylation 10.2 ATP12A ATP4A
25 bladder calculus 10.2 ATP12A ATP4A
26 ischemic neuropathy 10.2 ATP12A ATP4A
27 bile reflux 10.2 ATP12A ATP4A
28 capillary disease 10.2 ATP12A ATP4A
29 dyskinesia of esophagus 10.2 ATP12A ATP4A
30 anismus 10.2 ATP12A ATP4A
31 postsurgical hypothyroidism 10.2 ATP12A ATP4A
32 lymphocytic colitis 10.2 ATP12A ATP4A
33 esophageal atresia/tracheoesophageal fistula 10.2 ATP12A ATP4A
34 clostridium difficile colitis 10.2 ATP12A ATP4A
35 diarrhea 1, secretory chloride, congenital 10.2 ATP12A ATP4A
36 microscopic colitis 10.2 ATP12A ATP4A
37 laryngeal tuberculosis 10.1 ATP12A ATP4A
38 eosinophilic gastritis 10.1 ATP12A ATP4A
39 esophagus adenocarcinoma 10.1 ATP12A ATP4A
40 chronic intestinal vascular insufficiency 10.1 ATP12A ATP4A
41 esophagitis 10.1
42 polyposis, skin pigmentation, alopecia, and fingernail changes 10.1 ATP12A ATP4A
43 jejunoileitis 10.1 ATP12A ATP4A
44 pancreatic steatorrhea 10.1 ATP12A ATP4A
45 superior mesenteric artery syndrome 10.1 ATP12A ATP4A
46 duodenal disease 10.1 ATP12A ATP4A
47 gastric lymphoma 10.1 ATP12A ATP4A
48 lower urinary tract calculus 10.1 ATP12A ATP4A
49 myopathy, x-linked, with excessive autophagy 10.1 ATP12A ATP4A
50 aspiration pneumonia 10.1 ATP12A ATP4A

Comorbidity relations with Esophageal Candidiasis via Phenotypic Disease Network (PDN): (show all 18)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Bronchitis
Chronic Kidney Failure Decubitus Ulcer
Deficiency Anemia Esophageal Disease
Esophagitis Familial Atrial Fibrillation
Heart Disease Iron Deficiency Anemia
Ischemic Heart Disease Neutropenia
Oral Candidiasis Protein-Energy Malnutrition
Respiratory Failure Swallowing Disorders

Graphical network of the top 20 diseases related to Esophageal Candidiasis:



Diseases related to Esophageal Candidiasis

Symptoms & Phenotypes for Esophageal Candidiasis

Drugs & Therapeutics for Esophageal Candidiasis

Drugs for Esophageal Candidiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 42)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Caspofungin Approved Phase 3,Phase 2,Not Applicable 179463-17-3, 162808-62-0 468682 2826718
2
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 22916-47-8 4189
3
Fluconazole Approved, Investigational Phase 3,Not Applicable 86386-73-4 3365
4
Micafungin Approved, Investigational Phase 3,Phase 1 235114-32-6 3081921 477468
5
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
6
Itraconazole Approved, Investigational Phase 3,Not Applicable 84625-61-6 55283
7
Voriconazole Approved, Investigational Phase 3 137234-62-9 71616
8 Antifungal Agents Phase 3,Phase 2,Phase 1,Not Applicable
9 Echinocandins Phase 3,Phase 2,Phase 1
10 Anti-Infective Agents Phase 3,Phase 2,Phase 1,Not Applicable
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Not Applicable
12 Cytochrome P-450 Enzyme Inhibitors Phase 3,Not Applicable
13 Steroid Synthesis Inhibitors Phase 3,Not Applicable
14 Hormone Antagonists Phase 3,Phase 2,Not Applicable
15 Hormones Phase 3,Phase 2,Not Applicable
16 Cytochrome P-450 CYP2C9 Inhibitors Phase 3,Not Applicable
17 Cytochrome P-450 CYP2C19 Inhibitors Phase 3,Not Applicable
18 Cytochrome P-450 CYP3A Inhibitors Phase 3,Not Applicable
19 Pharmaceutical Solutions Phase 3,Not Applicable
20
Hydroxyitraconazole Phase 3,Not Applicable
21
Acyclovir Approved Phase 2 59277-89-3 2022
22
Anidulafungin Approved, Investigational Phase 2 166663-25-8 166548
23
Midazolam Approved, Illicit Phase 2 59467-70-8 4192
24
Budesonide Approved Phase 2 51333-22-3 63006 5281004
25
Fluticasone Approved, Experimental Phase 2 90566-53-3 62924
26 Antiviral Agents Phase 2
27 Antibiotics, Antitubercular Phase 2
28 Anti-Bacterial Agents Phase 2,Not Applicable
29 Autonomic Agents Phase 2
30 Respiratory System Agents Phase 2
31 Anti-Inflammatory Agents Phase 2
32 glucocorticoids Phase 2
33 Anti-Asthmatic Agents Phase 2
34 Bronchodilator Agents Phase 2
35 Peripheral Nervous System Agents Phase 2
36 Anti-Allergic Agents Phase 2
37 Dermatologic Agents Phase 2
38
Amphotericin B Approved, Investigational Not Applicable 1397-89-3 5280965 14956
39
Ketoconazole Approved, Investigational Not Applicable 65277-42-1 3823 47576
40 Liposomal amphotericin B Not Applicable
41 Antiparasitic Agents Not Applicable
42 Antiprotozoal Agents Not Applicable

Interventional clinical trials:

(show all 25)
# Name Status NCT ID Phase Drugs
1 A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults (MK-0991-066) Completed NCT00635648 Phase 3 caspofungin acetate
2 Comparative Trial of Micafungin Versus Fluconazole for Treating Esophageal Candidiasis Completed NCT00666185 Phase 3 Micafungin;Fluconazole
3 Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis Completed NCT00665639 Phase 3 micafungin;caspofungin
4 A Study of Fluconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems Completed NCT00002339 Phase 3 Fluconazole
5 Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081) Completed NCT00000676 Phase 3 Clotrimazole;Fluconazole
6 A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED) Completed NCT00717860 Phase 3 caspofungin acetate;Comparator: Micafungin sodium
7 A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection Completed NCT00784368 Phase 3 ITCZ Oral Solution;ITCZ-IV
8 A Study Of The Safety, Tolerability And Effective Of Voriconazole For The Treatment Of Serious Candida Infection And Candida Infection Of The Throat In Pediatric Patients Terminated NCT01092832 Phase 3 voriconazole
9 Acyclovir to Treat Patients Co-infected With HIV and Herpes Viruses in Uganda Completed NCT00405821 Phase 2 Acyclovir;Placebo
10 The Safety and Efficacy of Intravenous Anidulafungin as a Treatment for Azole-Refractory Mucosal Candidiasis (FRMC) Completed NCT00041704 Phase 2 Anidulafungin, VER002
11 A Study of Caspofungin (MK-0991) in Japanese Children and Adolescents With Documented Candida or Aspergillus Infections (MK-0991-074) Completed NCT01165320 Phase 2 Caspofungin
12 Dose-Ranging Study of Oral Viscous Budesonide in Pediatrics With Eosinophilic Esophagitis Completed NCT00762073 Phase 2 budesonide;placebo
13 Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE) Active, not recruiting NCT03191864 Phase 2 APT-1011;Placebo
14 Study of Mycamine® in Infants and Toddlers With Fungal Infections to Evaluate Safety and Blood Levels of the Drug Completed NCT00607763 Phase 1 Micafungin (Mycamine)
15 Study of Mycamine® in Children With Fungal Infections to Evaluate Safety and Blood Levels of the Drug Completed NCT00608335 Phase 1 Micafungin
16 Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. Completed NCT00002132 Not Applicable Itraconazole;Fluconazole
17 Evaluation of Amphotericin B in the Treatment of Biopsy Proven Candida Esophagitis in Immunocompromised Patients Completed NCT00002041 Not Applicable Amphotericin B
18 A Study of the Side Effects of L-743,872 in Men With Candidal Esophagitis Completed NCT00005921 Not Applicable L-743,872
19 A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems Completed NCT00002304 Not Applicable Ketoconazole;Fluconazole
20 A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women Completed NCT00000744 Not Applicable Fluconazole
21 A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected Patients Completed NCT00002438 Not Applicable Itraconazole
22 HIV Cohort Study At Johns Hopkins University, University of North Carolina at Chapel Hill and Vanderbilt University Completed NCT01339416
23 Non-interventional Study for Prevention and Treatment of Fungal Infections in Paediatric Patients in Asia/Oceania - ERADICATE Study Completed NCT03174457 Micafungin
24 Kaiser Permanente HIV Cohort Study Completed NCT01339403
25 A Study on the Safety and Effectiveness of Rilpivirine Hydrochloride (Edurant) Among Adult Filipino Patients With Human Immunodeficiency Virus Type-I Infection Withdrawn NCT01692470 No intervention

Search NIH Clinical Center for Esophageal Candidiasis

Genetic Tests for Esophageal Candidiasis

Anatomical Context for Esophageal Candidiasis

MalaCards organs/tissues related to Esophageal Candidiasis:

41
Skin, Kidney, Liver, Colon, Testes, Myeloid, Lung

Publications for Esophageal Candidiasis

Articles related to Esophageal Candidiasis:

(show top 50) (show all 123)
# Title Authors Year
1
Course of Esophageal Candidiasis and Outcomes of Patients at a Single Center. ( 29702297 )
2018
2
Cytology Preparations of Formalin Fixative Aid Detection of Giardia in Duodenal Biopsy Samples: A Helpful Tool for Diagnosing Esophageal Candidiasis as Well? ( 29762142 )
2018
3
Predictors of esophageal candidiasis among patients attending endoscopy unit in a tertiary hospital, Tanzania: a retrospective cross-sectional study. ( 29977259 )
2018
4
Challenges to "Classic" Esophageal Candidiasis: Looks Are Usually Deceiving. ( 28158394 )
2017
5
Narrow-band imaging can increase the visibility of fibrin caps after bleeding of esophageal varices: a case with extensive esophageal candidiasis. ( 28500570 )
2017
6
Recurrent episodes of esophageal candidiasis without dysphagia post-Guillain-BarrAc syndrome: an unusual presentation of achalasia. ( 29038193 )
2017
7
Safety, Efficacy, and Exposure-Response of Voriconazole in Pediatric Patients With Invasive Aspergillosis, Invasive Candidiasis or Esophageal Candidiasis. ( 27636722 )
2017
8
Esophageal candidiasis in HIV positive and HIV negative patients in a general hospital. ( 27728363 )
2016
9
Epigastric Distress Caused by Esophageal Candidiasis in 2 Patients Who Received Sorafenib Plus Radiotherapy for Hepatocellular Carcinoma: Case Report. ( 26986168 )
2016
10
Invasive Esophageal Candidiasis with Chronic Mediastinal Abscess and Fatal Pneumomediastinum. ( 27389822 )
2016
11
Antifungal Treatment is Not Required for Immunocompetent Individuals With Asymptomatic Esophageal Candidiasis. ( 26559270 )
2015
12
A phase 2, randomized, double-blind, multicenter trial to evaluate the safety and efficacy of three dosing regimens of isavuconazole compared with fluconazole in patients with uncomplicated esophageal candidiasis. ( 25561337 )
2015
13
A patient with chronic diarrhea, recurrent infections, and oropharyngeal and esophageal candidiasis. ( 25478924 )
2015
14
Esophageal Candidiasis as the Initial Manifestation of Acute Myeloid Leukemia. ( 26631899 )
2015
15
Long-Term Trends in Esophageal Candidiasis Prevalence and Associated Risk Factors with or without HIV Infection: Lessons from an Endoscopic Study of 80,219 Patients. ( 26208220 )
2015
16
The clinical course of asymptomatic esophageal candidiasis incidentally diagnosed in general health inspection. ( 26083902 )
2015
17
Is empiric therapy with fluconazole appropriate for esophageal candidiasis? ( 24424852 )
2014
18
Aphagia due to esophageal candidiasis in an immunocompetent patient. ( 25194226 )
2014
19
Clinical pharmacodynamic index identification for micafungin in esophageal candidiasis: dosing strategy optimization. ( 23959319 )
2013
20
A case of esophageal candidiasis in an adolescent who had frequently received budesonide nebulizing therapy. ( 24224152 )
2013
21
Relationship between clinical factors and severity of esophageal candidiasis according to Kodsi's classification. ( 23826847 )
2013
22
Factors associated with esophageal candidiasis and its endoscopic severity in the era of antiretroviral therapy. ( 23555571 )
2013
23
Prevalence and risk factors of esophageal candidiasis in healthy individuals: a single center experience in Korea. ( 23225813 )
2013
24
The potential of photodynamic therapy to treat esophageal candidiasis coexisting with esophageal cancer. ( 24378331 )
2013
25
Association of esophageal candidiasis and squamous cell carcinoma. ( 24371724 )
2012
26
Pharmacokinetics of micafungin in HIV positive patients with confirmed esophageal candidiasis. ( 21956255 )
2012
27
Eosinophilic esophagitis misdiagnosed twice as esophageal candidiasis. ( 20152316 )
2010
28
Optimal management of oropharyngeal and esophageal candidiasis in patients living with HIV infection. ( 22096388 )
2010
29
In vitro activity of anidulafungin and other agents against esophageal candidiasis-associated isolates from a phase 3 clinical trial. ( 20504981 )
2010
30
Esophageal candidiasis in an immunocompetent girl. ( 19718541 )
2009
31
Esophageal candidiasis--an adverse effect of inhaled corticosteroids therapy. ( 19484677 )
2009
32
The resistance to fluconazole in patients with esophageal candidiasis. ( 19466307 )
2009
33
The impact of esophageal candidiasis on hospital charges and costs across patient subgroups. ( 18036287 )
2008
34
Giardiasis diagnosed on esophageal brush smears in a case of chronic alcoholic liver disease with esophageal candidiasis. ( 18831025 )
2008
35
Esophageal candidiasis and Candida colonization in asthma patients on inhaled steroids. ( 18034973 )
2007
36
Posaconazole for the treatment of azole-refractory oropharyngeal and esophageal candidiasis in subjects with HIV infection. ( 17243069 )
2007
37
An elderly case of type 2 diabetes which developed in association with oral and esophageal candidiasis. ( 17409603 )
2007
38
Possible aggravation and recovery of slowly progressive type 1 diabetes by onset and resolution of oral and esophageal candidiasis. ( 17878660 )
2007
39
Role of posaconazole in the management of oropharyngeal and esophageal candidiasis. ( 18472974 )
2007
40
Safety and efficacy of posaconazole in the long-term treatment of azole-refractory oropharyngeal and esophageal candidiasis in patients with HIV infection. ( 17507324 )
2007
41
Caspofungin-resistant oral and esophageal candidiasis in a patient with AIDS. ( 17148982 )
2007
42
A murine model of esophageal candidiasis with local characteristic symptoms. ( 17579259 )
2007
43
Caspofungin in the treatment of azole-refractory esophageal candidiasis in kidney transplant recipients. ( 16757256 )
2006
44
Esophageal candidiasis as a side effect of inhaled fluticasone propionate dry powder: recovery by switching over to hydrofluoroalkane-134a beclomethasone dipropionate (HFA-BDP). ( 16724573 )
2006
45
Decline in esophageal candidiasis and use of antimycotics in European patients with HIV. ( 15984964 )
2005
46
Esophageal candidiasis. ( 16408552 )
2005
47
Caspofungin susceptibility testing of isolates from patients with esophageal candidiasis or invasive candidiasis: relationship of MIC to treatment outcome. ( 16127030 )
2005
48
A randomized, double-blind trial of anidulafungin versus fluconazole for the treatment of esophageal candidiasis. ( 15472806 )
2004
49
Echinocandins: ask not what they can do for esophageal candidiasis--ask what studies of esophageal candidiasis can do for them. ( 15472818 )
2004
50
Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans. ( 15388459 )
2004

Variations for Esophageal Candidiasis

Expression for Esophageal Candidiasis

Search GEO for disease gene expression data for Esophageal Candidiasis.

Pathways for Esophageal Candidiasis

Pathways related to Esophageal Candidiasis according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.44 CYP2C19 CYP2C9 CYP3A4
2
Show member pathways
11.72 CYP2C19 CYP2C9 CYP3A4
3
Show member pathways
11.57 CYP2C19 CYP2C9 CYP3A4
4
Show member pathways
11.5 CYP2C19 CYP2C9 CYP3A4
5
Show member pathways
11.4 CYP2C19 CYP2C9 CYP3A4
6
Show member pathways
11.3 CYP2C19 CYP2C9 CYP3A4
7
Show member pathways
11.17 CYP2C19 CYP2C9 CYP3A4
8 11.09 CYP2C9 CYP3A4
9 11.04 CYP2C19 CYP2C9 CYP3A4
10
Show member pathways
10.97 CYP2C9 CYP3A4
11
Show member pathways
10.9 CYP2C9 CYP3A4
12 10.89 CYP2C9 CYP3A4
13 10.8 CYP2C9 CYP3A4
14
Show member pathways
10.72 CYP2C19 CYP2C9 CYP3A4
15 10.3 CYP2C19 CYP2C9 CYP3A4
16 10.1 CYP2C9 CYP3A4

GO Terms for Esophageal Candidiasis

Cellular components related to Esophageal Candidiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 organelle membrane GO:0031090 8.8 CYP2C19 CYP2C9 CYP3A4

Biological processes related to Esophageal Candidiasis according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 steroid metabolic process GO:0008202 9.63 CYP2C19 CYP2C9 CYP3A4
2 potassium ion import across plasma membrane GO:1990573 9.58 ATP12A ATP4A
3 potassium ion import GO:0010107 9.58 ATP12A ATP4A
4 ATP hydrolysis coupled proton transport GO:0015991 9.57 ATP12A ATP4A
5 organic acid metabolic process GO:0006082 9.56 CYP2C19 CYP2C9
6 long-chain fatty acid biosynthetic process GO:0042759 9.55 CYP2C9 CYP3A4
7 epoxygenase P450 pathway GO:0019373 9.54 CYP2C19 CYP2C9
8 cellular sodium ion homeostasis GO:0006883 9.52 ATP12A ATP4A
9 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.51 ATP12A ATP4A
10 xenobiotic metabolic process GO:0006805 9.5 CYP2C19 CYP2C9 CYP3A4
11 cellular potassium ion homeostasis GO:0030007 9.49 ATP12A ATP4A
12 sodium ion export across plasma membrane GO:0036376 9.48 ATP12A ATP4A
13 omega-hydroxylase P450 pathway GO:0097267 9.43 CYP2C19 CYP2C9
14 oxidative demethylation GO:0070989 9.4 CYP2C9 CYP3A4
15 heterocycle metabolic process GO:0046483 9.37 CYP2C19 CYP3A4
16 drug metabolic process GO:0017144 9.33 CYP2C19 CYP2C9 CYP3A4
17 drug catabolic process GO:0042737 9.26 CYP2C9 CYP3A4
18 exogenous drug catabolic process GO:0042738 9.13 CYP2C19 CYP2C9 CYP3A4
19 monoterpenoid metabolic process GO:0016098 8.8 CYP2C19 CYP2C9 CYP3A4

Molecular functions related to Esophageal Candidiasis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 heme binding GO:0020037 9.63 CYP2C19 CYP2C9 CYP3A4
2 iron ion binding GO:0005506 9.61 CYP2C19 CYP2C9 CYP3A4
3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.54 CYP2C19 CYP2C9 CYP3A4
4 oxygen binding GO:0019825 9.49 CYP2C19 CYP3A4
5 arachidonic acid epoxygenase activity GO:0008392 9.48 CYP2C19 CYP2C9
6 monooxygenase activity GO:0004497 9.43 CYP2C19 CYP2C9 CYP3A4
7 sodium:potassium-exchanging ATPase activity GO:0005391 9.4 ATP12A ATP4A
8 caffeine oxidase activity GO:0034875 9.32 CYP2C9 CYP3A4
9 potassium:proton exchanging ATPase activity GO:0008900 9.16 ATP12A ATP4A
10 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 9.13 CYP2C19 CYP2C9 CYP3A4
11 steroid hydroxylase activity GO:0008395 8.8 CYP2C19 CYP2C9 CYP3A4

Sources for Esophageal Candidiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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