Esophageal Candidiasis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Esophageal Candidiasis

MalaCards integrated aliases for Esophageal Candidiasis:

Name: Esophageal Candidiasis ¹¹ ² ¹⁴ ⁷⁵

Candidiasis of the Esophagus ¹¹ ⁷¹

Esophageal Moniliasis ¹¹

Candidal Esophagitis ¹¹

Candida Esophagitis ¹¹

Esophageal Thrush ¹¹

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Gastrointestinal diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:13146

ICD9CM ³⁴ 112.84

NCIt ⁴⁹ C27027

SNOMED-CT ⁶⁸ 20639004

UMLS ⁷¹ C0239295

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Summaries for Esophageal Candidiasis

CDC: ² Candidiasis is an infection caused by a yeast (a type of fungus) called Candida. Candida normally lives inside the body (in places such as the mouth, throat, gut, and vagina) and on skin without causing any problems.1 Sometimes, Candida can multiply and cause an infection if the environment inside the mouth, throat, or esophagus changes in a way that encourages fungal growth. Candidiasis in the mouth and throat is also called "thrush" or oropharyngeal candidiasis. Candidiasis in the esophagus (the tube that connects the throat to the stomach) is called esophageal candidiasis or Candida esophagitis. Esophageal candidiasis is one of the most common infections in people living with HIV/AIDS

MalaCards based summary: Esophageal Candidiasis, also known as candidiasis of the esophagus, is related to oral candidiasis and laryngitis. An important gene associated with Esophageal Candidiasis is CD4 (CD4 Molecule), and among its related pathways/superpathways are PAK Pathway and T-cell activation SARS-CoV-2. The drugs Caspofungin and Micafungin have been mentioned in the context of this disorder. Affiliated tissues include skin, bone marrow and colon, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism

Disease Ontology: ¹¹ A candidiasis that involves fungal infection of the esophagus by Candida albicans in immunocompromised people, resulting in lesions, bleeding, painful swallowing and substernal pain.

Wikipedia: ⁷⁵ Esophageal candidiasis is an opportunistic infection of the esophagus by Candida albicans. The disease... more...

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Related Diseases for Esophageal Candidiasis

Diseases related to Esophageal Candidiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 646)

#	Related Disease	Score	Top Affiliating Genes
1	oral candidiasis	30.8	IL17A CLEC7A CD8A CD4 CCR6 CARD9
2	laryngitis	30.5	CD4 ATP4A ATP12A
3	viral esophagitis	30.4	ATP4A ATP12A
4	alcohol use disorder	30.4	CD4 CCR6 ATP12A
5	fungal esophagitis	30.3	ATP4A ATP12A
6	candidiasis	30.3	IL5 IL17A CYP51A1 CLEC7A CARD9 AIRE
7	esophagitis	30.3	IL5 IL13 CYP2C19 CCL26 CAPN14
8	hernia, hiatus	30.2	CYP2C19 ATP4A ATP12A
9	nutritional deficiency disease	30.2	CCR6 ATP4A ATP12A
10	pharyngitis	30.2	CD8A CD4 CCR6
11	peptic esophagitis	30.0	CYP2C19 CCR6 CCL26 ATP4A ATP12A
12	inflammatory bowel disease 1	29.9	IL17A CCR6 CARD9
13	gastritis	29.9	IL17A CYP2C19 CCR6 ATP4A
14	aphthous stomatitis	29.8	IL17A CD8A CD4 CCR6
15	pernicious anemia	29.8	CD4 CCR6 ATP4A ATP12A AIRE
16	aspergillosis	29.8	IL5 CLEC7A CCR6
17	peptic ulcer disease	29.8	CYP3A4 CYP2C19 CCR6 ATP4A ATP12A
18	syphilis	29.8	IL17A CD8A CD4 CCR6
19	spondyloarthropathy 1	29.7	IL17A CD8A CD4 CCR6
20	deficiency anemia	29.7	CD8A CD4 CCR6 ATP4A ATP12A
21	eosinophilic gastroenteritis	29.7	IL5 IL13 CCL26 ATP4A ATP12A
22	systemic scleroderma	29.6	IL17A IL13 CD8A CD4 CCR6
23	giardiasis	29.6	IL17A CD8A CD4 ATP4A ATP12A
24	immune deficiency disease	29.6	IL17A IL13 CYP3A4 CD8A CD4 CCR6
25	viral infectious disease	29.5	IL17A IL13 CD4 CCR6
26	meningitis	29.5	IL5 IL17A IL13
27	dyskinesia of esophagus	29.5	IL13 CCL26 CAPN14 ATP4A ATP12A
28	bilirubin metabolic disorder	29.4	CYP3A4 CYP2C19 CD8A CD4 ATP4A ATP12A
29	dermatitis	29.4	IL5 IL17A IL13 CCR6
30	ulcerative colitis	29.3	IL5 IL17A IL13 CCR6
31	esophagitis, eosinophilic, 1	29.2	IL5 IL13 CCR6 CCL26 CAPN14 ATP4A
32	colitis	29.2	IL5 IL17A IL13 CD4 CCR6
33	rhinitis	29.1	IL5 IL17A IL13 CYP3A4
34	intrinsic asthma	29.1	IL5 IL17A IL13 CD4 CCR6
35	gastroesophageal reflux	29.1	IL5 CYP3A4 CYP2C19 CCL26 ATP4A ATP12A
36	asthma	29.0	IL5 IL17A IL13 CYP3A4 CD4 CCR6
37	cryptococcal meningitis	28.9	IL17A CYP51A1 CLEC7A CD8A CD4 CCR6
38	pneumocystosis	28.9	IL17A CLEC7A CD8A CD4 CCR6 CARD9
39	respiratory failure	28.9	IL5 IL17A IL13 CD8A CD4 CCR6
40	chronic mucocutaneous candidiasis	28.8	IL17A CLEC7A CD8A CD4 CCR6 CARD9
41	allergic disease	28.8	IL5 IL17A IL13 CYP3A4 CD8A CD4
42	common cold	28.7	IL5 IL17A IL13 CD8A CD4 CCR6
43	dermatitis, atopic	28.7	IL5 IL17A IL13 CD8A CD4 CCR6
44	invasive aspergillosis	28.2	IL17A CYP51A1 CYP3A4 CYP2C19 CLEC7A CD4
45	skin disease	28.0	IL5 IL17A IL13 CYP3A4 CD8A CD4
46	fungal infectious disease	27.7	IL5 IL17A IL13 CYP51A1 CLEC7A CD8A
47	opportunistic mycosis	27.2	IL5 IL17A IL13 CYP51A1 CLEC7A CD8A
48	acquired immunodeficiency syndrome	10.6
49	human immunodeficiency virus type 1	10.4
50	pancreatic vasoactive intestinal peptide producing tumor	10.4	ATP4A ATP12A

Comorbidity relations with Esophageal Candidiasis via Phenotypic Disease Network (PDN): (show all 17)

Active Peptic Ulcer Disease	Acute Cystitis
Acute Kidney Failure	Bronchitis
Chronic Kidney Disease	Decubitus Ulcer
Deficiency Anemia	Esophageal Disease
Esophagitis	Familial Atrial Fibrillation
Heart Disease	Iron Deficiency Anemia
Neutropenia	Oral Candidiasis
Protein-Energy Malnutrition	Respiratory Failure
Swallowing Disorders

Graphical network of the top 20 diseases related to Esophageal Candidiasis:

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Symptoms & Phenotypes for Esophageal Candidiasis

GenomeRNAi Phenotypes related to Esophageal Candidiasis according to GeneCards Suite gene sharing:

²⁵

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Reduced mammosphere formation	GR00396-S	9.1	ATP4A CCR6 CLEC7A CYP51A1 IL17A IL5

MGI Mouse Phenotypes related to Esophageal Candidiasis:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	10.07	AIRE ATP12A ATP4A CARD9 CCL26 CCR6
2	digestive/alimentary	MP:0005381	9.81	AIRE ATP12A ATP4A CD4 CLEC7A CYP51A1
3	immune system	MP:0005387	9.7	AIRE ATP4A CARD9 CCR6 CD4 CD8A
4	hematopoietic system	MP:0005397	9.36	AIRE ATP4A CARD9 CCL26 CCR6 CD4

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Drugs & Therapeutics for Esophageal Candidiasis

Drugs for Esophageal Candidiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 23)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Caspofungin

Approved

Phase 3

179463-17-3, 162808-62-0

2826718

2

Micafungin

Approved, Investigational

Phase 3

235114-32-6

477468

3

Fluconazole

Approved, Investigational

Phase 3

86386-73-4

3365

4

Miconazole

Approved, Investigational, Vet_approved

Phase 3

22916-47-8

4189

5

Clotrimazole

Approved, Vet_approved

Phase 3

23593-75-1

2812

6

Voriconazole

Approved

Phase 3

137234-62-9

71616

7

Anti-Infective Agents

Phase 3

8

Antifungal Agents

Phase 3

9

Hormones

Phase 3

10

Hormone Antagonists

Phase 3

11

Cytochrome P-450 Enzyme Inhibitors

Phase 3

12

Cytochrome P-450 CYP3A Inhibitors

Phase 3

13

Echinocandins

Phase 1

14

Ketoconazole

Approved, Investigational

65277-42-1, 142128-57-2

47576 3823 638701

15

Itraconazole

Approved, Investigational

84625-61-6

55283

16

Amphotericin B

Approved, Investigational

1397-89-3

5280965

17

Pharmaceutical Solutions

18

Hydroxyitraconazole

108222

19

Amebicides

20

Anti-Bacterial Agents

21

Antiprotozoal Agents

22

Antiparasitic Agents

23

Liposomal amphotericin B

Interventional clinical trials:

(show all 11)

#	Name	Status	NCT ID	Phase	Drugs
1	A Phase 3, Randomized, Double-Blind, Comparative Trial of Two Dosing Regimens of Micafungin (FK463) Versus Caspofungin for the Treatment of Esophageal Candidiasis	Completed	NCT00665639	Phase 3	micafungin;caspofungin
2	A Phase 3, Randomized, Double-Blind, Comparative Trial of Micafungin Versus Fluconazole for the Treatment of Esophageal Candidiasis	Completed	NCT00666185	Phase 3	Micafungin;Fluconazole
3	A Non-comparative, Multicenter, Open-label Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin Acetate (MK-0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults	Completed	NCT00635648	Phase 3	caspofungin acetate
4	An Open Multicenter Trial of Fluconazole Oral Suspension in the Treatment of Esophageal Candidiasis in Immunocompromised Patients	Completed	NCT00002339	Phase 3	Fluconazole
5	A Prospective, Open-label, Non-comparative Study To Assess The Safety, Tolerability And Efficacy Of Voriconazole For The Primary And Salvage Treatment Of Invasive Candidiasis, Candidemia, And Esophageal Candidiasis In Pediatric Subjects	Terminated	NCT01092832	Phase 3	voriconazole
6	A Phase 1, Open-Label Study Of The Safety And Pharmacokinetics Of Repeated-Dose Micafungin (FK463) In Children (2-5 Years AND 6-11 Years) And Adolescents (12-16 Years) With Esophageal Candidiasis Or Other Invasive Candidiasis	Completed	NCT00608335	Phase 1	Micafungin
7	A Phase 1, Open-Label Study Of The Safety And Pharmacokinetics Of Repeated-Dose Micafungin (FK463) In Infants And Toddlers (≥4 Months TO < 24 Months Of Age) With Esophageal Candidiasis Or Other Invasive Candidiasis	Completed	NCT00607763	Phase 1	Micafungin (Mycamine)
8	A Randomized Comparative Multicenter Trial of Fluconazole and Ketoconazole in the Treatment of Esophageal Candidiasis in Immunocompromised Patients	Completed	NCT00002304		Ketoconazole;Fluconazole
9	Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.	Completed	NCT00002132		Itraconazole;Fluconazole
10	Evaluation of Amphotericin B in the Treatment of Biopsy Proven Candida Esophagitis in Immunocompromised Patients	Completed	NCT00002041		Amphotericin B
11	An Open, Serial-Panel, Multiple-Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of L-743,872 in Patients With Candida Esophagitis	Completed	NCT00005921		L-743,872

Search NIH Clinical Center for Esophageal Candidiasis

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Genetic Tests for Esophageal Candidiasis

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Anatomical Context for Esophageal Candidiasis

Organs/tissues related to Esophageal Candidiasis:

MalaCards : Skin, Bone Marrow, Colon, Liver, Kidney, Bone, Lung

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Publications for Esophageal Candidiasis

Articles related to Esophageal Candidiasis:

(show top 50) (show all 896)

#	Title	Authors	PMID	Year
1	Fungal esophagitis associated with tuberculous pericarditis in an human immunodeficiency virus-positive patient: a case report. ⁶²	Silva GM...de Lima-Neto RG	36345027	2022
2	Broncho-esophageal fistula as a complication of transmural candida esophagitis in a patient with malnutrition. ⁶²	Diaz Alcazar MDM...Casado Caballero FJ	34453968	2022
3	Prevalence and risk factors for Candida esophagitis among human immunodeficiency virus-negative individuals. ⁶²	Chen YH...Hsu PI	36338217	2022
4	Esophageal Intramural Pseudodiverticulosis Diagnosed by Combining Esophagogastroduodenoscopy, Esophagography, and High-resolution manometry: A Case Report. ⁶²	Kunimitsu A...Kamei T	36223924	2022
5	Case report: Tumor collision in the colon, adenocarcinoma - lymphoma. ⁶²	Zapata Palomino M...Zorrilla JO	36380539	2022
6	Late-onset opportunistic infections while receiving anti-retroviral therapy in Latin America: burden and risk factors. ⁶²	Nunez I...Caro-Vega Y	35768025	2022
7	The estimated burden of fungal diseases in Mali. ⁶²	Doumbo SN...Denning DW	36270216	2022
8	Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) and esophageal rupture by candida infection: A case report and review. ⁶²	Domingues-Ferreira M...Auler ME	35597148	2022
9	Verrucous carcinoma of the esophagus with complete response after chemoradiotherapy. ⁶²	Hashimoto M...Fujiwara T	35781764	2022
10	Nausea and vomiting caused by candida esophagitis in an elderly frail patient. ⁶²	Kiba T...Tsuboi M	35822125	2022
11	Efficacy of Cochleated Amphotericin B in Mouse and Human Mucocutaneous Candidiasis. ⁶²	Desai JV...Freeman AF	35699443	2022
12	Double acute esophageal candidiasis and cytomegalovirus (CMV) infection in a young healthy patient: a call to think about HIV infection in AIDS. ⁶²	Ojeda Gomez A...Uceda Porta F	35170324	2022
13	Recidivant odynophagia secondary to persistent esophageal candidiasis in an immunocompetent patient: the importance of brush cytology. ⁶²	Lopez Pena C...Soler Gongora M	35078324	2022
14	Adrenocorticotropic hormone-secreting pancreatic neuroendocrine carcinoma with multiple organ infections and widespread thrombosis: A case report. ⁶²	Yoshihara A...Yano Y	35979125	2022
15	[Acute Diseases of the Esophagus - Esophagitis]. ⁶²	Gerdes C...Neesse A	35440200	2022
16	Esophageal Candidiasis in a Non-HIV Patient: A Primary Care Diagnosis. ⁶²	Rodrigues S...Martins TG	35602778	2022
17	A case of esophageal candidiasis in a psoriatic patient treated with ixekizumab: Should treatment be discontinued? ⁶²	Ruggiero A...Gallo L	35137503	2022
18	Deep learning-based detection of eosinophilic esophagitis. ⁶²	Guimaraes P...Casper M	34058769	2022
19	Risk of candidiasis associated with interleukin-17 inhibitors: A real-world observational study of multiple independent sources. ⁶²	Davidson L...Kullberg BJ	34950923	2022
20	CARD9 Expression Pattern, Gene Dosage, and Immunodeficiency Phenotype Revisited. ⁶²	Goel S...Rosenzweig SD	34791587	2022
21	Case Report: Eosinophilic Esophagitis in a Patient With a Novel STAT1 Gain-of-Function Pathogenic Variant. ⁶²	Scott O...Roifman CM	35126392	2022
22	Simultaneous Massive Esophageal Mucosal Candidiasis and Profound Cytomegaloviral Esophageal Ulcers with Recurrence of Both Infections 12 Years Later in a Patient with Long-Standing AIDS: Endoscopic, Radiologic, and Pathologic Findings. ⁶²	Gill I...Cappell MS	35265384	2022
23	Association of Candida esophagitis with acute esophageal necrosis. ⁶²	Warraich MS...Khaqan MA	36304599	2022
24	Prevalence, Predictors, and Outcomes of Esophageal Candidiasis in Cirrhosis: An Observational Study With Systematic Review and Meta-Analysis (CANDID-VIEW). ⁶²	Verma N...Singh V	35068792	2022
25	Abrupt Development of Esophageal Candidiasis after Secukinumab Treatment in a Psoriatic Patient. ⁶²	Kang HJ...Kim TY	34858013	2021
26	Effectiveness and Safety of High- vs Low-Dose Swallowed Topical Steroids for Maintenance Treatment of Eosinophilic Esophagitis: A Multicenter Observational Study. ⁶²	Greuter T...Katzka DA	32798703	2021
27	Multisystem Autoimmune Inflammatory Disease, Including Colitis, Due to Inborn Error of Immunity. ⁶²	Malik A...Derfalvi B	34686572	2021
28	Effect of Dysphagia on Hospital Outcomes and Readmissions in Patients with Human Immunodeficiency Virus. ⁶²	Nustas R...Qayed E	34729612	2021
29	Efficacy and acceptability of different anti-fungal interventions in oropharyngeal or esophageal candidiasis in HIV co-infected adults: a pilot network meta-analysis. ⁶²	Zeng BS...Chen CH	33899657	2021
30	Risk factors for the development of esophageal candidiasis among patients in community hospital. ⁶²	Ogiso H...Shimizu M	34667198	2021
31	A 30-Year-Old Immune Deficient Woman With Persistent Cough and Shortness of Breath. ⁶²	Fels Elliott DR...Farver CF	34625181	2021
32	Initial diagnosis of HIV/AIDS in patients presenting to the emergency department: Imaging and clinical findings at a single institution. ⁶²	Spierling A...Ramaiya NH	34020125	2021
33	Immunologic biomarkers, morbidity and mortality among HIV patients hospitalised in a Tertiary Care Hospital in the Brazilian Amazon. ⁶²	Gama WM...Nogueira PA	34445956	2021
34	Dysphagia, reflux and related sequelae due to altered physiology in scleroderma. ⁶²	Kadakuntla A...Tadros M	34497445	2021
35	Association of Eosinophilic Esophagitis and Human Immunodeficiency Virus. ⁶²	Asfari MM...Vega KJ	32851497	2021
36	Laparoscopic Sleeve Gastrectomy Esophageal Candidiasis an Exceptional Complication of Laparoscopic Sleeve Gastrectomy: First Case Report. ⁶²	Saidani A...Chebbi F	33866533	2021
37	Genotyping, antifungal susceptibility, enzymatic activity, and phenotypic variation in Candida albicans from esophageal candidiasis. ⁶²	Jafarian H...Mahmoudabadi AZ	33988259	2021
38	Oropharyngeal candidiasis outcomes in renal transplant recipients receiving nystatin versus no antifungal prophylaxis. ⁶²	Ky TQ...Cotiguala L	33387388	2021
39	Development of Epidermoid Metaplasia of the Mucosa in Association with Esophageal Intramural Pseudodiverticulosis and Candidiasis. ⁶²	Shintaku M...Torii I	34594170	2021
40	Candida esophagitis incidentally detected by 18F-FDG PET/CT in a patient with CNS lymphoma. ⁶²	Bayar M...Eskazan AE	34084527	2021
41	Mortality in Perinatally HIV-infected Adolescents After Transition to Adult Care in Spain. ⁶²	Berzosa Sanchez A...Corispe-Faro Cohort Working Group, Spain	33264211	2021
42	Candida Esophagitis Associated With Adalimumab for Hidradenitis Suppurativa. ⁶²	Nazarian RS...Smith BL	33956612	2021
43	Clinical Characteristics and Manifestations of Fungal Esophagitis: A Single-Center Experience in South China. ⁶²	Zhan SK...Zheng FP	33531895	2021
44	The burden of serious fungal infections in Sierra Leone: a national estimate. ⁶²	Lakoh S...Denning DW	34262759	2021
45	Formulation, in vitro characterization and optimization of taste-masked orally disintegrating co-trimoxazole tablet by direct compression. ⁶²	Tafere C...Yehualaw A	33725014	2021
46	Upper gastrointestinal endoscopy; A study from a rural population of Sindh, Pakistan. ⁶²	Kamran M...Ahmed J	33437243	2021
47	Verrucous esophageal carcinoma is a unique indolent subtype of squamous cell carcinoma: a systematic review and individual patient regression analysis. ⁶²	Li DK...Bazerbachi F	33079233	2021
48	Auto-brewery syndrome caused by oral fungi and periodontal disease bacteria. ⁶²	Takahashi G...Yamada Y	33976897	2021
49	Efficacy and safety of peroral endoscopic myotomy after prior sleeve gastrectomy and gastric bypass surgery. ⁶²	Kolb JM...Wagh MS	33362906	2020
50	Verrucous carcinoma of the esophagus - a case report and literature review. ⁶²	Frieling T...Hemmerlein B	33036050	2020

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Genes for Esophageal Candidiasis

Genes related to Esophageal Candidiasis (0 elite genes):

(show all 16)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CD4	CD4 Molecule	Protein Coding	7.5	DISEASES inferred ¹⁴
2	ATP12A	ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit	Protein Coding	6.91	DISEASES inferred ¹⁴
3	ATP4A	ATPase H+/K+ Transporting Subunit Alpha	Protein Coding	6.91	DISEASES inferred ¹⁴
4	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	6.01	DISEASES inferred ¹⁴ ¹⁴
5	CYP51A1	Cytochrome P450 Family 51 Subfamily A Member 1	Protein Coding	5.98	DISEASES inferred ¹⁴
6	CCL26	C-C Motif Chemokine Ligand 26	Protein Coding	5.88	DISEASES inferred ¹⁴
7	CD8A	CD8a Molecule	Protein Coding	5.58	DISEASES inferred ¹⁴
8	CAPN14	Calpain 14	Protein Coding	5.57	DISEASES inferred ¹⁴
9	AIRE	Autoimmune Regulator	Protein Coding	5.44	DISEASES inferred ¹⁴
10	CARD9	Caspase Recruitment Domain Family Member 9	Protein Coding	5.42	DISEASES inferred ¹⁴
11	CYP3A4	Cytochrome P450 Family 3 Subfamily A Member 4	Protein Coding	5.38	DISEASES inferred ¹⁴
12	CYP2C19	Cytochrome P450 Family 2 Subfamily C Member 19	Protein Coding	5.34	DISEASES inferred ¹⁴
13	IL17A	Interleukin 17A	Protein Coding	5.23	DISEASES inferred ¹⁴
14	IL13	Interleukin 13	Protein Coding	5.06	DISEASES inferred ¹⁴
15	CLEC7A	C-Type Lectin Domain Containing 7A	Protein Coding	5.02	DISEASES inferred ¹⁴
16	IL5	Interleukin 5	Protein Coding	4.98	DISEASES inferred ¹⁴

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Variations for Esophageal Candidiasis

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Expression for Esophageal Candidiasis

Search GEO for disease gene expression data for Esophageal Candidiasis.

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Pathways for Esophageal Candidiasis

Pathways related to Esophageal Candidiasis according to GeneCards Suite gene sharing:

(show all 11)

#	Super pathways	Score	Top Affiliating Genes
1	PAK Pathway ⁶⁴ Show member pathways Antioxidant Action of Vitamin-C ⁶⁴ Epithelial Adherens Junctions ⁶⁴	13	IL5 IL17A IL13 CD4 CCR6 CCL26
2	T-cell activation SARS-CoV-2 ⁷⁴ Show member pathways T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection ⁷⁴	11.8	IL5 IL17A CD8A CD4
3	Hematopoietic Stem Cells and Lineage-specific Markers ⁶⁵	11.72	IL5 CD8A CD4
4	Allograft rejection ⁷⁴	11.55	IL5 IL17A IL13
5	Th2 Differentiation ⁶⁵	11.21	IL5 IL13 CD4
6	Innate Lymphoid Cells Differentiation ⁶⁵	11	IL5 IL17A IL13 CD8A CD4 CCR6
7	Development and heterogeneity of the ILC family ⁷⁴	10.94	IL5 IL17A IL13
8	Cytokines and inflammatory response ⁷⁴	10.79	IL5 IL13 CD4
9	Venlafaxine Pathway, Pharmacokinetics ⁶⁰ Show member pathways Citalopram and Escitalopram Pathway, Pharmacokinetics ⁶⁰ Defective SLC6A2 causes orthostatic intolerance (OI) ⁶⁶ Lansoprazole Pathway, Pharmacokinetics ⁶⁰ Omeprazole and Esomeprazole Pathway, Pharmacokinetics ⁶⁰	10.73	CYP3A4 CYP2C19
10	Immune infiltration in pancreatic cancer ⁷⁴	10.56	IL5 IL17A IL13
11	IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types ⁶⁵	10.51	IL5 IL13

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GO Terms for Esophageal Candidiasis

Biological processes related to Esophageal Candidiasis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	T cell activation	GO:0042110	9.85	CLEC7A CD8A CD4
2	heterocycle metabolic process	GO:0046483	9.71	CYP3A4 CYP2C19
3	positive regulation of interleukin-23 production	GO:0032747	9.62	IL17A CLEC7A
4	monoterpenoid metabolic process	GO:0016098	9.56	CYP3A4 CYP2C19
5	immune response	GO:0006955	9.5	IL5 IL17A IL13 CD8A CD4 CCR6
6	regulation of proton transport	GO:0010155	9.46	ATP4A IL13
7	positive regulation of cytokine production involved in inflammatory response	GO:1900017	9.43	IL17A CLEC7A CARD9

Molecular functions related to Esophageal Candidiasis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	P-type sodium:potassium-exchanging transporter activity	GO:0005391	9.56	ATP4A ATP12A
2	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO:0016705	9.33	CYP51A1 CYP3A4 CYP2C19
3	P-type potassium transmembrane transporter activity	GO:0008556	8.96	ATP4A ATP12A
4	P-type potassium:proton transporter activity	GO:0008900	8.92	ATP4A ATP12A

Sources

Sources for Esophageal Candidiasis

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: ESP018 MIFTS: 47	Esophageal Candidiasis Categories: Gastrointestinal diseases, Immune diseases, Infectious diseases	Data Licensing For inquiries, contact: [email protected]
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