MCID: ESP023
MIFTS: 53

Esophageal Disease

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Esophageal Disease

MalaCards integrated aliases for Esophageal Disease:

Name: Esophageal Disease 12 15
Esophageal Diseases 55 44 73
Esophageal Disorder 76
Ulcer of Esophagus 73
Esophageal Ulcer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6050
ICD10 33 K22.9
ICD9CM 35 530 530.9
MeSH 44 D004935
NCIt 50 C3027
SNOMED-CT 68 37657006

Summaries for Esophageal Disease

Disease Ontology : 12 A gastrointestinal system disease that is located in the esophagus.

MalaCards based summary : Esophageal Disease, also known as esophageal diseases, is related to barrett esophagus and esophageal varix, and has symptoms including nausea and vomiting, constipation and abdominal pain. An important gene associated with Esophageal Disease is WWOX (WW Domain Containing Oxidoreductase), and among its related pathways/superpathways are WNT Signaling and Small cell lung cancer. The drugs Alginic acid and Carvedilol have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and trachea, and related phenotypes are homeostasis/metabolism and digestive/alimentary

Wikipedia : 76 The esophagus (American English) or oesophagus (British English) (/ɪ�?s�?f�?ɡ�?s/), commonly known as... more...

Related Diseases for Esophageal Disease

Diseases related to Esophageal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 166)
# Related Disease Score Top Affiliating Genes
1 barrett esophagus 31.9 CCND1 GAST PTGS2 TP53
2 esophageal varix 30.2 ALB ATP12A ATP4A
3 esophagitis 30.1 CCL26 HRH2 PTGS2 TP53 TRPV1
4 esophagitis, eosinophilic, 1 30.0 ATP12A ATP4A CCL26
5 gastroesophageal reflux 29.8 CCL26 GAST HRH2 PTGS2 TP53 TRPV1
6 peptic esophagitis 29.8 ATP12A ATP4A HRH2
7 esophageal cancer 29.2 ALB ALDH2 C2orf40 CCND1 CEACAM5 PTGS2
8 achalasia 11.2
9 fungal esophagitis 10.3 ATP12A ATP4A
10 diclofenac allergy 10.3 ATP12A ATP4A
11 gastroduodenal crohn's disease 10.3 ATP12A ATP4A
12 neonatal candidiasis 10.3 ATP12A ATP4A
13 squamous papillomatosis 10.3 ATP12A ATP4A WWOX
14 mucoepidermoid esophageal carcinoma 10.3 CEACAM5 WWOX
15 toxic megacolon 10.3 ATP12A ATP4A
16 gastric antral vascular ectasia 10.3 ATP12A ATP4A
17 dyskinesia of esophagus 10.3 ATP12A ATP4A TEF
18 bartholin's duct cyst 10.3 SMUG1 TP53
19 esophageal atresia/tracheoesophageal fistula 10.3 ATP12A ATP4A TEF
20 esophageal candidiasis 10.3 ATP12A ATP4A
21 bladder calculus 10.3 ATP12A ATP4A SMUG1
22 paine syndrome 10.3 ATP12A ATP4A TRPV1
23 liver lymphoma 10.3 CEACAM5 SMUG1
24 acute laryngitis 10.3 ATP12A ATP4A
25 cellular ependymoma 10.3 SMUG1 TP53
26 esophageal adenosquamous carcinoma 10.3 CEACAM5 WWOX
27 splenic tuberculosis 10.3 CEACAM5 SMUG1
28 aspiration pneumonitis 10.3 ATP12A ATP4A HRH2
29 eosinophilic gastritis 10.3 ATP12A ATP4A CCL26
30 capillary disease 10.3 ALB ATP12A ATP4A
31 colloid adenoma 10.3 SMUG1 TP53
32 photoallergic dermatitis 10.3 ATP12A ATP4A PTGS2
33 polyposis, skin pigmentation, alopecia, and fingernail changes 10.3 ALB ATP12A ATP4A
34 laryngitis 10.3 ATP12A ATP4A HRH2
35 jejunoileitis 10.3 ALB ATP12A ATP4A
36 gallbladder squamous cell carcinoma 10.3 CEACAM5 SMUG1
37 glomangiosarcoma 10.3 KANTR TP53
38 chronic laryngitis 10.3 ATP12A ATP4A HRH2
39 malignant acrospiroma 10.3 CEACAM5 SMUG1
40 intracranial chondrosarcoma 10.3 CEACAM5 TP53
41 bile reflux 10.3 ATP12A ATP4A PTGS2
42 jejunal adenocarcinoma 10.3 CCND1 SMUG1 WWOX
43 rumination disorder 10.3 ATP12A ATP4A
44 ostertagiasis 10.3 ALB GAST
45 connective tissue cancer 10.3 SMUG1 TP53 TRPV1
46 male reproductive system disease 10.3 CCND1 TP53 TRPV1
47 anismus 10.3 ATP12A ATP4A KANTR
48 gastrointestinal tuberculosis 10.3 ALB SMUG1
49 chronic intestinal vascular insufficiency 10.3 ATP12A ATP4A KANTR
50 protoplasmic astrocytoma 10.3 PTGS2 SMUG1 TP53

Comorbidity relations with Esophageal Disease via Phenotypic Disease Network (PDN): (show all 26)


Active Peptic Ulcer Disease Acute Cystitis
Acute Pancreatitis Bronchitis
Chronic Kidney Failure Decubitus Ulcer
Deficiency Anemia Duodenitis
Dyskinesia of Esophagus Esophageal Cancer
Esophageal Candidiasis Esophageal Varix
Esophagitis Esophagus Carcinoma in Situ
Heart Disease Hypertension, Essential
Intestinal Obstruction Iron Deficiency Anemia
Ischemic Heart Disease Mallory-Weiss Syndrome
Megaesophagus Paralytic Ileus
Peptic Esophagitis Protein-Energy Malnutrition
Schizophreniform Disorder Swallowing Disorders

Graphical network of the top 20 diseases related to Esophageal Disease:



Diseases related to Esophageal Disease

Symptoms & Phenotypes for Esophageal Disease

UMLS symptoms related to Esophageal Disease:


nausea and vomiting, constipation, abdominal pain, diarrhea, tinnitus, snoring, coughing, sore throat, icterus, signs and symptoms, digestive, vertigo/dizziness, equilibration disorder, dyspepsia, heartburn, gastrointestinal gas, digestive system symptom

MGI Mouse Phenotypes related to Esophageal Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10 AAAS ALB ALDH2 ATP12A ATP4A CCND1
2 digestive/alimentary MP:0005381 9.97 AAAS ALB ATP12A ATP4A CCND1 GAST
3 endocrine/exocrine gland MP:0005379 9.96 AAAS ALB ALDH2 ATP4A CCND1 GAST
4 liver/biliary system MP:0005370 9.5 ALB ALDH2 PTGS2 TEF TP53 TRPV1
5 neoplasm MP:0002006 9.32 ALB ALDH2 ATP4A CCND1 GAST PTGS2

Drugs & Therapeutics for Esophageal Disease

Drugs for Esophageal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 706)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Alginic acid Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9005-32-7
2
Carvedilol Approved, Investigational Phase 4,Not Applicable 72956-09-3 2585
3
Domperidone Approved, Investigational, Vet_approved Phase 4,Phase 3,Not Applicable 57808-66-9 3151
4
Dopamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 51-61-6, 62-31-7 681
5
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 73590-58-6 4594
6
Calcium polycarbophil Approved Phase 4 126040-58-2
7
Propranolol Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 525-66-6 4946
8
Methylene blue Approved, Investigational Phase 4,Not Applicable 61-73-4
9
Nadolol Approved Phase 4,Phase 3 42200-33-9 39147
10
Rabeprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 117976-89-3 5029
11
Trimebutine Approved Phase 4 39133-31-8
12
Lansoprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 103577-45-3 3883
13
Dexlansoprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 103577-45-3, 138530-94-6 9578005
14
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
15
Esomeprazole Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 161796-78-7, 119141-88-7 4594 9579578
16
mometasone furoate Approved, Vet_approved Phase 4,Phase 2 83919-23-7
17
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 137-58-6 3676
18
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Not Applicable 51-43-4 5816
19
Racepinephrine Approved Phase 4,Phase 2,Not Applicable 329-65-7 838
20
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Not Applicable 437-38-7 3345
21
Levobupivacaine Approved, Investigational Phase 4 27262-47-1 92253
22
Iron Approved Phase 4,Phase 1 7439-89-6 23925
23
Pravastatin Approved Phase 4 81093-37-0 54687
24
Lypressin Approved Phase 4,Not Applicable 50-57-7
25
Somatostatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51110-01-1, 38916-34-6 53481605
26
Terlipressin Approved, Investigational Phase 4,Phase 3,Not Applicable 14636-12-5 72081
27
Octreotide Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 83150-76-9 383414 6400441
28
Pantoprazole Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 102625-70-7 4679
29
Ethiodized oil Approved, Investigational Phase 4,Phase 3,Not Applicable 8008-53-5
30
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2,Not Applicable 90566-53-3 62924
31
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 51-21-8 3385
32
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 15663-27-1 2767 441203 84093
33
Oxaliplatin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 61825-94-3 43805 6857599 5310940 9887054
34
Irinotecan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 100286-90-6, 97682-44-5 60838
35
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58-05-9 6006 143
36
Levoleucovorin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 68538-85-2
37
Acetylcholine Approved Phase 4,Phase 2,Not Applicable 51-84-3 187
38
Zinc Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 7440-66-6
39
Docetaxel Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 114977-28-5 148124
40
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
41
Methylnaltrexone Approved Phase 4 83387-25-1, 916055-93-1 6603824
42
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 50-24-8 5755
43
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 302-25-0
44
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 83-43-2 6741
45
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 1,Not Applicable 2921-57-5
46
Naloxone Approved, Vet_approved Phase 4 465-65-6 5284596
47
Metoclopramide Approved, Investigational Phase 4,Phase 3,Not Applicable 364-62-5 4168
48
Remifentanil Approved Phase 4 132875-61-7 60815
49
Ethanolamine oleate Approved Phase 4,Phase 3 2272-11-9
50
Phenylephrine Approved Phase 4,Phase 2 59-42-7 6041

Interventional clinical trials:

(show top 50) (show all 2699)
# Name Status NCT ID Phase Drugs
1 Effect of Magnesium Alginate on Gastroesophageal Reflux in Infants. Unknown status NCT02806453 Phase 4
2 The Effect of Carvedilol VS Endoscopic Therapy in Primary Prophylaxis of High-risk Esophageal Gastric Variceal Bleeding Unknown status NCT02695732 Phase 4 Carvedilol
3 Research of Efficient Use of Omeprazole in Combination With Domperidone in Gastroesophageal Reflux Disease of Mild to Moderate Severity Unknown status NCT02140073 Phase 4 omeprazole+domperidone SR;omeprazole
4 Phase IV Study of the Impact of Dietary Fibers on Symptoms and Esophageal Motility in Patients With Non-erosive GERD Unknown status NCT01882088 Phase 4 Mucofalk
5 Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD) Unknown status NCT01822106 Phase 4
6 Development of Applications of the Bravo® pH Monitoring System and Evaluation of Its Performance Unknown status NCT01503476 Phase 4
7 LGG for Prevention of Infectious Complications During PPI Treatment in Children Unknown status NCT01782118 Phase 4
8 The Effect of Carvedilol Vs Propranolol in Cirrhotic Patients With Variceal Bleeding Unknown status NCT02385422 Phase 4 Carvedilol;Propranolol
9 Personalized Peroral Endoscopic Myotomy for Achalasia Unknown status NCT01570621 Phase 4
10 Primary Prevention of Gastric Variceal Bleeding : Endoscopic Treatment Versus Non-selective Beta-blocker Unknown status NCT01298271 Phase 4 propranolol
11 Trimebutine Maleate Combined With Rabeprazole in Patients With Grade A or B Reflux Esophagitis Whose Symptoms Refractory to Rabeprazole Unknown status NCT02986685 Phase 4 Trimebutine Maleate;rabeprazole
12 Treatment Effect Between Dexlansoprazole and Double-dose Lansoprazole in Obesity Patients With Reflux Esophagitis Unknown status NCT02759393 Phase 4 Dexlansoprazole;Lansoprazole
13 Preventing Recurrent Bleeding After Eradication of Esophageal Varices Unknown status NCT02740166 Phase 4 propranolol
14 Radiofrequency in the Treatment of Barrett's Oesophagus Unknown status NCT02558504 Phase 4
15 Esomeprazole Plus Alginate vs. Esomeprazole Alone for Treatment of Nighttime Reflux Symptom and Sleep Disturbances Unknown status NCT02277886 Phase 4 sodium alginate;esomeprazole
16 Dexlansoprazole to Treat Laryngopharyngeal Reflux and Lingual Tonsil Hypertrophy Unknown status NCT01328652 Phase 4 dexlansoprazole
17 Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD) Unknown status NCT01110811 Phase 4
18 Intrathoracic Esophagogastric Anastomosis After Robot Assisted Minimally Invasive Esophagectomy Using STRATAFIX Unknown status NCT02609425 Phase 4
19 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4 lansoprazole;placebo
20 Postoperative Pain Management After Minimally Invasive Esophagectomy Unknown status NCT02042313 Phase 4
21 Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices Unknown status NCT01970748 Phase 4 Propranolol
22 Iron Replacement in Oesophagogastric Neoplasia Unknown status NCT01927328 Phase 4 Iron isomaltoside 1000
23 Study to Evaluate the Efficacy of Pravastatin on Survival and Recurrence of Advanced Gastroesophageal Cancer Unknown status NCT01038154 Phase 4 Pravastatin
24 Trial of Enteral Nutrition Enriched With Eicosapentaenoic Acid (EPA) in Upper Gastrointestinal Cancer Surgery Unknown status NCT00790140 Phase 4
25 A Clinical Trial of a Radiation Sensitizer in Radiochemotherapy for Thoracic Esophageal Squamous Carcinoma Unknown status NCT00642239 Phase 4 placebo;Sodium Glycididazole
26 Endoesophageal Cryotherapy For Ablating Barrett's Esophagus and Early Stage Esophageal Cancer Unknown status NCT00628784 Phase 4
27 A Randomized, Double-Blind, Placebo-Controlled Study of Gastroesophageal Reflux Disease Therapy. Unknown status NCT00237068 Phase 4 Lansoprazole; Solutab
28 Opioids and Esophageal Function Completed NCT01012960 Phase 4 methylnaltrexone
29 Caustic Esophageal Burns in Children and High Doses of Methylprednisolone Completed NCT02002078 Phase 4 methylprednisolon
30 Opioid Effects on Swallowing and Esophageal Sphincter Pressure Completed NCT01191645 Phase 4 naloxone;remifentanil;Sodium Chloride;metoclopramide
31 Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding Completed NCT00966355 Phase 4 Terlipressin;Somatostatin;Octreotide
32 Evaluation of Patients With Non-cardiac Chest Pain Completed NCT00476398 Phase 4
33 Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy Completed NCT00526331 Phase 4
34 Codeine on Pharyngeal and Esophageal Motility Completed NCT03784105 Phase 4 Codeine Phosphate;Siripus simplex
35 Rate of Complete Symptom Relief, Prevention of Symptom Relapse: Grades A and B Esophagitis of Esomeprazole Therapy Completed NCT01874535 Phase 4 Esomeprazole 40 mg
36 The Effect of Corticotrophin-releasing Hormone (CRH) on Esophageal Motility in Healthy Volunteers Completed NCT02736734 Phase 4 CRH
37 Esophageal Fully Covered Metal Stents in Caustic Strictures Study Completed NCT01899300 Phase 4
38 WallFlex Esophageal Fully Covered (FC) Benign Anastomotic Stricture Completed NCT01699542 Phase 4
39 Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group Comparison of the Remission Rates of Once Daily Treatment With Esomeprazole 20mg and Lansoprazole 15mg for 6 Months in Patients Whose EE Has Been Healed Completed NCT00644735 Phase 4 Esomeprazole;Lansoprazole
40 A Multicenter, Randomized, Double Blind, Double Dummy, Parallel-Group Efficacy Study Comparing 8 Weeks of Treatment With Esomeprazole Magnesium (40mg qd) to Lansoprazole (30mg qd) for the Healing of Erosive Esophagitis in Patients With Moderate or Severe Erosive Esophagitis Completed NCT00641602 Phase 4 Esomeprazole;Lansoprazole
41 Intravenous (IV) Pantoprazole in Erosive Esophagitis Completed NCT00133770 Phase 4 pantoprazole
42 A Randomized Controlled Trial Comparing Band Ligation and Cyanoacrylate Injection for Esophageal Varices Completed NCT00799851 Phase 4 cyanoacrylate injection
43 Barrett's Esophagus - 315 - 3 Way Cross Over Completed NCT00637988 Phase 4 Esomeprazole;Aspirin;Rofecoxib
44 Barrett's Esophagus - 315 - 3 Way Cross-Over Completed NCT00637559 Phase 4 Esomeprazole Magnesium
45 An Open Label pH Comparison of Esomeprazole and Lansoprazole in Barrett's Esophagus Patients Completed NCT00352261 Phase 4 Esomeprazole;Lansoprazole
46 Carvedilol as an Adjunct to Endoscopic Cyanoacrylate Injection for Secondary Prophylaxis of Gastric Variceal Bleeding Completed NCT02504723 Phase 4 carvedilol;cyanoacrylate
47 Neuromuscular Electroestimulation and Respiratory Muscle Training in Subacute Stroke Completed NCT02473432 Phase 4
48 Hemodynamic Effects of Terlipressin and High Dose Octreotide Completed NCT02119884 Phase 4 Terlipressin;Octreotide
49 Evaluation of Two Different Thickening Products in Patients With Dysphagia Completed NCT01651975 Phase 4
50 Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft Completed NCT01507207 Phase 4

Search NIH Clinical Center for Esophageal Disease

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: esophageal diseases

Genetic Tests for Esophageal Disease

Anatomical Context for Esophageal Disease

MalaCards organs/tissues related to Esophageal Disease:

41
Lung, Heart, Trachea, Breast, Colon, Testes, Skin

The Foundational Model of Anatomy Ontology organs/tissues related to Esophageal Disease:

19
The Esophagus

Publications for Esophageal Disease

Articles related to Esophageal Disease:

(show top 50) (show all 225)
# Title Authors Year
1
Serial Endoscopic Evaluation of Esophageal Disease in a Cancer Model: A Paradigm Shift for Esophageal Adenocarcinoma (EAC) Drug Discovery and Development. ( 30142016 )
2018
2
The Role of Novel Functional Probes in the Evaluation and Treatment of Esophageal Disease. ( 30268301 )
2018
3
Expanding Role of Third Space Endoscopy in the Management of Esophageal Diseases. ( 29435819 )
2018
4
Patient-Reported Outcomes in Esophageal Diseases. ( 29452645 )
2018
5
The arachidonic acid metabolism protein-protein interaction network and its expression pattern in esophageal diseases. ( 29636881 )
2018
6
Nasojejunal-stent technique: A new system to prevent fully covered metal stent migration in the treatment of benign esophageal diseases. ( 29779221 )
2018
7
Esophageal Diseases. ( 29274867 )
2018
8
Unsedated in Office Transgastrostomy Esophagoscopy (TGE) to Monitor Therapy in Pediatric Esophageal Disease. ( 28505050 )
2017
9
To anchor or not to anchor self-expanding metal stents in malignant esophageal disease: Is this still a question? ( 29090244 )
2017
10
Can We Use Diet to Effectively Treat Esophageal Disease? A Review of the Current Literature. ( 28730507 )
2017
11
Utility of esophageal mucosal impedance as a diagnostic test for esophageal disease. ( 28437259 )
2017
12
Evolution in the Treatment of Esophageal Disease at a Single Academic Institution: 2004-2013. ( 28486000 )
2017
13
Impact of Surgeon Specialty on Perioperative Outcomes of Surgery for Benign Esophageal Diseases: A NSQIP Analysis. ( 28594583 )
2017
14
Whole greater than the parts: integrated esophageal centers (IEC) and advanced training in esophageal diseases. ( 28859396 )
2017
15
Uniportal video-assisted thoracoscopic surgery in esophageal diseases: an introduction. ( 29302458 )
2017
16
Emerging endoscopic techniques for the identification of esophageal disease. ( 26753504 )
2016
17
Incidence, reasons, and risk factors for readmission after surgery for benign distal esophageal disease. ( 27365228 )
2016
18
An unusual cause of dysphagia: Isolated IgG 4-related esophageal disease. ( 28000632 )
2016
19
Literature Analysis of the Treatment of Benign Esophageal Disease with Stent. ( 27186033 )
2016
20
Understanding the sensory irregularities of esophageal disease. ( 26890720 )
2016
21
Palliation of Concomitant Tracheobronchial and Esophageal Disease Using a Combined Airway and Esophageal Approach. ( 27157053 )
2016
22
Functional lumen imaging probe: the functional lumen imaging probe side of esophageal disease. ( 27030931 )
2016
23
Current treatment options for esophageal diseases. ( 27391867 )
2016
24
Autophagy and its current relevance to the diagnosis and clinical management of esophageal diseases. ( 27526024 )
2016
25
Advances in the evaluation and management of esophageal disease of systemic sclerosis. ( 25475597 )
2015
26
Preface. Esophageal disease. ( 25965140 )
2015
27
Foreword. Esophageal disease. ( 25965139 )
2015
28
Clinical outcomes of self-expandable stent placement for benign esophageal diseases: A pooled analysis of the literature. ( 25685270 )
2015
29
Unexpected esophageal diseases appeared in thyroid resections. ( 25888936 )
2015
30
Predisposing factors for larynx preservation strategies with non-surgical multimodality treatment for locally advanced (T3-4) larynx, hypopharynx and cervical esophageal disease. ( 25202116 )
2014
31
Diet and esophageal disease. ( 25266021 )
2014
32
IgG4-Related Esophageal Disease Presenting as Esophagitis Dissecans Superficialis With Chronic Strictures. ( 24883156 )
2014
33
Time trends of US hospitalization for esophageal disease. ( 24440940 )
2014
34
Esophageal diseases. ( 25127938 )
2014
35
Esophageal diseases. ( 25133481 )
2014
36
Role of robotic-assisted surgery in benign esophageal diseases. ( 27637519 )
2014
37
Eosinophilic esophagitis: an immune-mediated esophageal disease. ( 23579771 )
2013
38
Esophageal disease. ( 23948187 )
2013
39
Screening pre-bariatric surgery patients for esophageal disease with esophageal capsule endoscopy. ( 24115815 )
2013
40
Esophageal disease. ( 23990483 )
2013
41
Innovative techniques in evaluating the esophagus; imaging of esophageal morphology and function; and drugs for esophageal disease. ( 24117631 )
2013
42
Safety of endoscopic removal of self-expandable stents after treatment of benign esophageal diseases. ( 23261092 )
2013
43
Benign and malignant esophageal diseases. ( 23452639 )
2013
44
Research advances in esophageal diseases: bench to bedside. ( 24167725 )
2013
45
New progress in endoscopic treatment of esophageal diseases. ( 24222940 )
2013
46
Redo laparoscopic repair of benign esophageal disease. ( 22608677 )
2012
47
Glycomic expression in esophageal disease. ( 24957772 )
2012
48
Comparison of 2 expandable stents for malignant esophageal disease: a randomized controlled trial. ( 22726466 )
2012
49
Update on endoscopic diagnosis, management and surveillance strategies of esophageal diseases. ( 22523612 )
2012
50
Expandable stents for benign esophageal disease. ( 21684459 )
2011

Variations for Esophageal Disease

Expression for Esophageal Disease

Search GEO for disease gene expression data for Esophageal Disease.

Pathways for Esophageal Disease

Pathways related to Esophageal Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.96 CCND1 GAST PTGS2 TP53
2 11.3 CCND1 PTGS2 TP53
3 10.84 CCND1 PTGS2 TP53
4 9.5 ATP4A GAST HRH2

GO Terms for Esophageal Disease

Biological processes related to Esophageal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to ATP GO:0071318 9.4 PTGS2 TRPV1
2 cellular sodium ion homeostasis GO:0006883 9.37 ATP12A ATP4A
3 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.32 ATP12A ATP4A
4 cellular potassium ion homeostasis GO:0030007 9.26 ATP12A ATP4A
5 sodium ion export across plasma membrane GO:0036376 9.16 ATP12A ATP4A
6 mitotic G1 DNA damage checkpoint GO:0031571 8.96 CCND1 TP53
7 response to organonitrogen compound GO:0010243 8.8 CCND1 PTGS2 TRPV1

Molecular functions related to Esophageal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Esophageal Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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