MCID: ESP023
MIFTS: 59

Esophageal Disease

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Esophageal Disease

MalaCards integrated aliases for Esophageal Disease:

Name: Esophageal Disease 12 15 17
Esophageal Diseases 56 45 74
Esophageal Disorder 77
Ulcer of Esophagus 74
Esophageal Ulcer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6050
ICD9CM 36 530 530.9
MeSH 45 D004935
NCIt 51 C3027
SNOMED-CT 69 37657006
ICD10 34 K22.1 K22.9

Summaries for Esophageal Disease

Disease Ontology : 12 A gastrointestinal system disease that is located in the esophagus.

MalaCards based summary : Esophageal Disease, also known as esophageal diseases, is related to esophagitis and esophageal varix, and has symptoms including nausea and vomiting, constipation and abdominal pain. An important gene associated with Esophageal Disease is ATP12A (ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit), and among its related pathways/superpathways are WNT Signaling and Thyroid hormone signaling pathway. The drugs Carvedilol and Omeprazole have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and t cells, and related phenotypes are digestive/alimentary and endocrine/exocrine gland

Wikipedia : 77 The esophagus (American English) or oesophagus (British English) (/ɪˈsɒfəɡəs/), commonly known as the... more...

Related Diseases for Esophageal Disease

Diseases related to Esophageal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 138)
# Related Disease Score Top Affiliating Genes
1 esophagitis 30.5 CCL26 HRH2 PTGS2 TP53
2 esophageal varix 30.5 ALB ATP12A ATP4A
3 esophagitis, eosinophilic, 1 30.4 ATP12A ATP4A CCL26
4 dyskinesia of esophagus 30.2 ATP12A ATP4A TEF
5 active peptic ulcer disease 30.1 ATP12A ATP4A HRH2 PTGS2
6 gastroesophageal reflux 30.1 CCL26 GAST HRH2 PTGS2 TP53
7 peptic esophagitis 30.0 ATP12A ATP4A HRH2
8 barrett esophagus 29.9 CCND1 GAST PTGS2 TP53
9 esophageal cancer 29.0 ADH1B ALB ALDH2 CCND1 CEACAM5 PLCE1
10 achalasia 11.2
11 fungal esophagitis 10.5 ATP12A ATP4A
12 diclofenac allergy 10.5 ATP12A ATP4A
13 gastroduodenal crohn's disease 10.5 ATP12A ATP4A
14 neonatal candidiasis 10.5 ATP12A ATP4A
15 squamous papillomatosis 10.5 ATP12A ATP4A
16 toxic megacolon 10.5 ATP12A ATP4A
17 esophageal atresia/tracheoesophageal fistula 10.5 ATP12A ATP4A TEF
18 gastric antral vascular ectasia 10.5 ATP12A ATP4A
19 esophageal candidiasis 10.5 ATP12A ATP4A
20 aspiration pneumonitis 10.5 ATP12A ATP4A HRH2
21 capillary disease 10.5 ALB ATP12A ATP4A
22 acute laryngitis 10.5 ATP12A ATP4A
23 eosinophilic gastritis 10.5 ATP12A ATP4A CCL26
24 photoallergic dermatitis 10.5 ATP12A ATP4A PTGS2
25 polyposis, skin pigmentation, alopecia, and fingernail changes 10.5 ALB ATP12A ATP4A
26 laryngitis 10.5 ATP12A ATP4A HRH2
27 jejunoileitis 10.5 ALB ATP12A ATP4A
28 chronic laryngitis 10.5 ATP12A ATP4A HRH2
29 bile reflux 10.5 ATP12A ATP4A PTGS2
30 protoplasmic astrocytoma 10.5 PTGS2 TP53
31 intracranial chondrosarcoma 10.4 CEACAM5 TP53
32 functional gastric disease 10.4 ATP12A ATP4A HRH2
33 glomangiosarcoma 10.4 KANTR TP53
34 ostertagiasis 10.4 ALB GAST
35 malignant spiradenoma 10.4 CEACAM5 TP53
36 anismus 10.4 ATP12A ATP4A KANTR
37 trichostrongyloidiasis 10.4 ALB GAST
38 lymphoma, mucosa-associated lymphoid type 10.4 ATP12A ATP4A CCND1
39 laryngeal tuberculosis 10.4 ATP12A ATP4A KANTR
40 gastrointestinal neuroendocrine benign tumor 10.4 ATP12A ATP4A GAST
41 granulomatous gastritis 10.4 ATP12A ATP4A GAST
42 chronic intestinal vascular insufficiency 10.4 ATP12A ATP4A KANTR
43 recurrent respiratory papillomatosis 10.4 PTGS2 TP53
44 gastric neuroendocrine neoplasm 10.4 ATP12A ATP4A GAST
45 duodenitis 10.4 ATP12A ATP4A GAST
46 rumination disorder 10.4 ATP12A ATP4A
47 lateral medullary syndrome 10.4 ATP12A ATP4A KANTR
48 cloacal exstrophy 10.4 ATP12A ATP4A KANTR
49 aspiration pneumonia 10.4 ALB ATP12A ATP4A TEF
50 gastric lymphoma 10.4 ALB ATP12A ATP4A TP53

Comorbidity relations with Esophageal Disease via Phenotypic Disease Network (PDN): (show all 26)


Active Peptic Ulcer Disease Acute Cystitis
Acute Pancreatitis Bronchitis
Chronic Kidney Failure Decubitus Ulcer
Deficiency Anemia Duodenitis
Dyskinesia of Esophagus Esophageal Cancer
Esophageal Candidiasis Esophageal Varix
Esophagitis Esophagus Carcinoma in Situ
Heart Disease Hypertension, Essential
Intestinal Obstruction Iron Deficiency Anemia
Ischemic Heart Disease Mallory-Weiss Syndrome
Megaesophagus Paralytic Ileus
Peptic Esophagitis Protein-Energy Malnutrition
Schizophreniform Disorder Swallowing Disorders

Graphical network of the top 20 diseases related to Esophageal Disease:



Diseases related to Esophageal Disease

Symptoms & Phenotypes for Esophageal Disease

UMLS symptoms related to Esophageal Disease:


nausea and vomiting, constipation, abdominal pain, diarrhea, tinnitus, snoring, sore throat, icterus, signs and symptoms, digestive, coughing, vertigo/dizziness, equilibration disorder, dyspepsia, heartburn, gastrointestinal gas, digestive system symptom

MGI Mouse Phenotypes related to Esophageal Disease:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.96 AAAS ALB ATP12A ATP4A CCND1 GAST
2 endocrine/exocrine gland MP:0005379 9.85 AAAS ALB ALDH2 ATP4A CCND1 GAST
3 homeostasis/metabolism MP:0005376 9.77 AAAS ALB ALDH2 ATP12A ATP4A CCND1
4 neoplasm MP:0002006 9.23 ALB ALDH2 ATP4A CCND1 GAST PLCE1

Drugs & Therapeutics for Esophageal Disease

Drugs for Esophageal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 758)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carvedilol Approved, Investigational Phase 4,Not Applicable 72956-09-3 2585
2
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 73590-58-6 4594
3
Domperidone Approved, Investigational, Vet_approved Phase 4,Phase 3,Not Applicable 57808-66-9 3151
4
Dopamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 62-31-7, 51-61-6 681
5
Propranolol Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 525-66-6 4946
6
Methylene blue Approved, Investigational Phase 4,Not Applicable 61-73-4
7
Nadolol Approved Phase 4,Phase 3 42200-33-9 39147
8
Trimebutine Approved Phase 4 39133-31-8
9
Rabeprazole Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 117976-89-3 5029
10
Lansoprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 103577-45-3 3883
11
Dexlansoprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 138530-94-6, 103577-45-3 9578005
12
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 50-78-2 2244
13
Esomeprazole Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 161796-78-7, 161973-10-0, 119141-88-7 9568614 4594
14
Calcium polycarbophil Approved Phase 4 126040-58-2
15
mometasone furoate Approved, Investigational, Vet_approved Phase 4,Phase 2 83919-23-7
16
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 137-58-6 3676
17
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Not Applicable 51-43-4 5816
18
Racepinephrine Approved Phase 4,Phase 2,Not Applicable 329-65-7 838
19
Levobupivacaine Approved, Investigational Phase 4 27262-47-1 92253
20
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Not Applicable 437-38-7 3345
21
Iron isomaltoside 1000 Approved, Investigational Phase 4 1370654-58-2
22
Iron Approved, Experimental Phase 4,Phase 1 7439-89-6, 15438-31-0 27284 23925
23
Pravastatin Approved Phase 4 81093-37-0 54687
24
Terlipressin Approved, Investigational Phase 4,Phase 3,Not Applicable 14636-12-5 72081
25
Octreotide Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 83150-76-9 6400441 383414
26
Somatostatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 38916-34-6, 51110-01-1 53481605
27
Pantoprazole Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 102625-70-7 4679
28 Ethiodized oil Approved, Investigational Phase 4,Phase 3,Not Applicable 8008-53-5
29
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2,Not Applicable 90566-53-3 62924
30
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 51-21-8 3385
31
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 15663-27-1 2767 441203 84093
32
Zinc Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 7440-66-6 32051
33
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58-05-9 143 6006
34
Irinotecan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 100286-90-6, 97682-44-5 60838
35
Levoleucovorin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 68538-85-2
36
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 61825-94-3 43805 6857599 5310940 9887054
37
Acetylcholine Approved, Investigational Phase 4,Phase 2,Not Applicable 51-84-3 187
38
Prednisone Approved, Vet_approved Phase 4,Phase 1,Not Applicable 53-03-2 5865
39
Docetaxel Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 114977-28-5 148124
40
Ethanol Approved Phase 4 64-17-5 702
41
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
42
Methylnaltrexone Approved Phase 4 916055-93-1, 83387-25-1 6603824
43
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 302-25-0
44
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-24-8 5755
45
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2921-57-5
46
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83-43-2 6741
47
Naloxone Approved, Vet_approved Phase 4 465-65-6 5284596
48
Remifentanil Approved Phase 4 132875-61-7 60815
49
Metoclopramide Approved, Investigational Phase 4,Phase 3,Not Applicable 364-62-5 4168
50
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 93-14-1 3516

Interventional clinical trials:

(show top 50) (show all 2784)
# Name Status NCT ID Phase Drugs
1 The Effect of Carvedilol VS Endoscopic Therapy in Primary Prophylaxis of High-risk Esophageal Gastric Variceal Bleeding Unknown status NCT02695732 Phase 4 Carvedilol
2 Research of Efficient Use of Omeprazole in Combination With Domperidone in Gastroesophageal Reflux Disease of Mild to Moderate Severity Unknown status NCT02140073 Phase 4 omeprazole+domperidone SR;omeprazole
3 The Effect of Carvedilol Vs Propranolol in Cirrhotic Patients With Variceal Bleeding Unknown status NCT02385422 Phase 4 Carvedilol;Propranolol
4 Personalized Peroral Endoscopic Myotomy for Achalasia Unknown status NCT01570621 Phase 4
5 Primary Prevention of Gastric Variceal Bleeding : Endoscopic Treatment Versus Non-selective Beta-blocker Unknown status NCT01298271 Phase 4 propranolol
6 Trimebutine Maleate Combined With Rabeprazole in Patients With Grade A or B Reflux Esophagitis Whose Symptoms Refractory to Rabeprazole Unknown status NCT02986685 Phase 4 Trimebutine Maleate;rabeprazole
7 Effect of Magnesium Alginate on Gastroesophageal Reflux in Infants. Unknown status NCT02806453 Phase 4
8 Treatment Effect Between Dexlansoprazole and Double-dose Lansoprazole in Obesity Patients With Reflux Esophagitis Unknown status NCT02759393 Phase 4 Dexlansoprazole;Lansoprazole
9 Preventing Recurrent Bleeding After Eradication of Esophageal Varices Unknown status NCT02740166 Phase 4 propranolol
10 Radiofrequency in the Treatment of Barrett's Oesophagus Unknown status NCT02558504 Phase 4
11 Esomeprazole Plus Alginate vs. Esomeprazole Alone for Treatment of Nighttime Reflux Symptom and Sleep Disturbances Unknown status NCT02277886 Phase 4 sodium alginate;esomeprazole
12 Phase IV Study of the Impact of Dietary Fibers on Symptoms and Esophageal Motility in Patients With Non-erosive GERD Unknown status NCT01882088 Phase 4 Mucofalk
13 Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD) Unknown status NCT01822106 Phase 4
14 LGG for Prevention of Infectious Complications During PPI Treatment in Children Unknown status NCT01782118 Phase 4
15 Development of Applications of the Bravo® pH Monitoring System and Evaluation of Its Performance Unknown status NCT01503476 Phase 4
16 Dexlansoprazole to Treat Laryngopharyngeal Reflux and Lingual Tonsil Hypertrophy Unknown status NCT01328652 Phase 4 dexlansoprazole
17 Intrathoracic Esophagogastric Anastomosis After Robot Assisted Minimally Invasive Esophagectomy Using STRATAFIX Unknown status NCT02609425 Phase 4
18 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4 lansoprazole;placebo
19 Postoperative Pain Management After Minimally Invasive Esophagectomy Unknown status NCT02042313 Phase 4
20 Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices Unknown status NCT01970748 Phase 4 Propranolol
21 Iron Replacement in Oesophagogastric Neoplasia Unknown status NCT01927328 Phase 4 Iron isomaltoside 1000
22 Study to Evaluate the Efficacy of Pravastatin on Survival and Recurrence of Advanced Gastroesophageal Cancer Unknown status NCT01038154 Phase 4 Pravastatin
23 Trial of Enteral Nutrition Enriched With Eicosapentaenoic Acid (EPA) in Upper Gastrointestinal Cancer Surgery Unknown status NCT00790140 Phase 4
24 A Clinical Trial of a Radiation Sensitizer in Radiochemotherapy for Thoracic Esophageal Squamous Carcinoma Unknown status NCT00642239 Phase 4 placebo;Sodium Glycididazole
25 Endoesophageal Cryotherapy For Ablating Barrett's Esophagus and Early Stage Esophageal Cancer Unknown status NCT00628784 Phase 4
26 A Randomized, Double-Blind, Placebo-Controlled Study of Gastroesophageal Reflux Disease Therapy. Unknown status NCT00237068 Phase 4 Lansoprazole; Solutab
27 Opioids and Esophageal Function Completed NCT01012960 Phase 4 methylnaltrexone
28 Caustic Esophageal Burns in Children and High Doses of Methylprednisolone Completed NCT02002078 Phase 4 methylprednisolon
29 Opioid Effects on Swallowing and Esophageal Sphincter Pressure Completed NCT01191645 Phase 4 naloxone;remifentanil;Sodium Chloride;metoclopramide
30 Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding Completed NCT00966355 Phase 4 Terlipressin;Somatostatin;Octreotide
31 Evaluation of Patients With Non-cardiac Chest Pain Completed NCT00476398 Phase 4
32 Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy Completed NCT00526331 Phase 4
33 Codeine on Pharyngeal and Esophageal Motility Completed NCT03784105 Phase 4 Codeine Phosphate;Siripus simplex
34 Rate of Complete Symptom Relief, Prevention of Symptom Relapse: Grades A and B Esophagitis of Esomeprazole Therapy Completed NCT01874535 Phase 4 Esomeprazole 40 mg
35 The Effect of Corticotrophin-releasing Hormone (CRH) on Esophageal Motility in Healthy Volunteers Completed NCT02736734 Phase 4 CRH
36 Esophageal Fully Covered Metal Stents in Caustic Strictures Study Completed NCT01899300 Phase 4
37 WallFlex Esophageal Fully Covered (FC) Benign Anastomotic Stricture Completed NCT01699542 Phase 4
38 Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group Comparison of the Remission Rates of Once Daily Treatment With Esomeprazole 20mg and Lansoprazole 15mg for 6 Months in Patients Whose EE Has Been Healed Completed NCT00644735 Phase 4 Esomeprazole;Lansoprazole
39 A Multicenter, Randomized, Double Blind, Double Dummy, Parallel-Group Efficacy Study Comparing 8 Weeks of Treatment With Esomeprazole Magnesium (40mg qd) to Lansoprazole (30mg qd) for the Healing of Erosive Esophagitis in Patients With Moderate or Severe Erosive Esophagitis Completed NCT00641602 Phase 4 Esomeprazole;Lansoprazole
40 Intravenous (IV) Pantoprazole in Erosive Esophagitis Completed NCT00133770 Phase 4 pantoprazole
41 A Randomized Controlled Trial Comparing Band Ligation and Cyanoacrylate Injection for Esophageal Varices Completed NCT00799851 Phase 4 cyanoacrylate injection
42 Carvedilol as an Adjunct to Endoscopic Cyanoacrylate Injection for Secondary Prophylaxis of Gastric Variceal Bleeding Completed NCT02504723 Phase 4 carvedilol;cyanoacrylate
43 Neuromuscular Electroestimulation and Respiratory Muscle Training in Subacute Stroke Completed NCT02473432 Phase 4
44 Hemodynamic Effects of Terlipressin and High Dose Octreotide Completed NCT02119884 Phase 4 Terlipressin;Octreotide
45 Evaluation of Two Different Thickening Products in Patients With Dysphagia Completed NCT01651975 Phase 4
46 Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft Completed NCT01507207 Phase 4
47 Opioid Induced Swallowing Difficulties and Risk for Pulmonary Aspiration Completed NCT01495377 Phase 4 Remifentanil;Placebo;Technetium
48 Time Interval for Endoscopic Variceal Ligation Completed NCT01291277 Phase 4
49 Comparison of the Effect of Rabeprazole 50 mg DDR Capsules and 20 mg Enteric-coated Tablets Completed NCT03037606 Phase 4 Rabelis DDR 50 mg Capsules;Pariet 20 mg Enteric Coated Tablets
50 The Efficacy of Lansoprazole and Domperidone Combination on Intragastric and Intraesophageal Acidity Completed NCT02958046 Phase 4 Lansoprazole/Domperidone

Search NIH Clinical Center for Esophageal Disease

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: esophageal diseases

Genetic Tests for Esophageal Disease

Anatomical Context for Esophageal Disease

MalaCards organs/tissues related to Esophageal Disease:

42
Lung, Testes, T Cells, Lymph Node, Liver, Breast, Bone

The Foundational Model of Anatomy Ontology organs/tissues related to Esophageal Disease:

20
The Esophagus

Publications for Esophageal Disease

Articles related to Esophageal Disease:

(show top 50) (show all 229)
# Title Authors Year
1
Combined airway and esophageal stents implantation for malignant tracheobronchial and esophageal disease: A STROBE-compliant article. ( 30653162 )
2019
2
Variations in the Clinical Course of Patients with Herpes Simplex Virus Esophagitis Based on Immunocompetence and Presence of Underlying Esophageal Disease. ( 30725296 )
2019
3
Evaluation of Esophageal Contraction Reserve Using HRM in Symptomatic Esophageal Disease. ( 30920423 )
2019
4
Serial Endoscopic Evaluation of Esophageal Disease in a Cancer Model: A Paradigm Shift for Esophageal Adenocarcinoma (EAC) Drug Discovery and Development. ( 30142016 )
2018
5
Unsedated In-office Transgastrostomy Esophagoscopy to Monitor Therapy in Pediatric Esophageal Disease. ( 28505050 )
2018
6
The Role of Novel Functional Probes in the Evaluation and Treatment of Esophageal Disease. ( 30268301 )
2018
7
Esophageal Diseases. ( 29274867 )
2018
8
Expanding Role of Third Space Endoscopy in the Management of Esophageal Diseases. ( 29435819 )
2018
9
Patient-Reported Outcomes in Esophageal Diseases. ( 29452645 )
2018
10
The arachidonic acid metabolism protein-protein interaction network and its expression pattern in esophageal diseases. ( 29636881 )
2018
11
Nasojejunal-stent technique: A new system to prevent fully covered metal stent migration in the treatment of benign esophageal diseases. ( 29779221 )
2018
12
Spectroscopy for Esophageal Diseases. ( 30804721 )
2018
13
Utility of esophageal mucosal impedance as a diagnostic test for esophageal disease. ( 28437259 )
2017
14
Evolution in the Treatment of Esophageal Disease at a Single Academic Institution: 2004-2013. ( 28486000 )
2017
15
Can We Use Diet to Effectively Treat Esophageal Disease? A Review of the Current Literature. ( 28730507 )
2017
16
To anchor or not to anchor self-expanding metal stents in malignant esophageal disease: Is this still a question? ( 29090244 )
2017
17
Impact of Surgeon Specialty on Perioperative Outcomes of Surgery for Benign Esophageal Diseases: A NSQIP Analysis. ( 28594583 )
2017
18
Whole greater than the parts: integrated esophageal centers (IEC) and advanced training in esophageal diseases. ( 28859396 )
2017
19
Uniportal video-assisted thoracoscopic surgery in esophageal diseases: an introduction. ( 29302458 )
2017
20
An unusual cause of dysphagia: Isolated IgG 4-related esophageal disease. ( 28000632 )
2016
21
Emerging endoscopic techniques for the identification of esophageal disease. ( 26753504 )
2016
22
Understanding the sensory irregularities of esophageal disease. ( 26890720 )
2016
23
Functional lumen imaging probe: The FLIP side of esophageal disease. ( 27030931 )
2016
24
Palliation of Concomitant Tracheobronchial and Esophageal Disease Using a Combined Airway and Esophageal Approach. ( 27157053 )
2016
25
Literature Analysis of the Treatment of Benign Esophageal Disease with Stent. ( 27186033 )
2016
26
Incidence, reasons, and risk factors for readmission after surgery for benign distal esophageal disease. ( 27365228 )
2016
27
Current treatment options for esophageal diseases. ( 27391867 )
2016
28
Autophagy and its current relevance to the diagnosis and clinical management of esophageal diseases. ( 27526024 )
2016
29
Advances in the evaluation and management of esophageal disease of systemic sclerosis. ( 25475597 )
2015
30
Foreword. Esophageal disease. ( 25965139 )
2015
31
Preface. Esophageal disease. ( 25965140 )
2015
32
Clinical outcomes of self-expandable stent placement for benign esophageal diseases: A pooled analysis of the literature. ( 25685270 )
2015
33
Unexpected esophageal diseases appeared in thyroid resections. ( 25888936 )
2015
34
Time trends of US hospitalization for esophageal disease. ( 24440940 )
2014
35
IgG4-Related Esophageal Disease Presenting as Esophagitis Dissecans Superficialis With Chronic Strictures. ( 24883156 )
2014
36
Predisposing factors for larynx preservation strategies with non-surgical multimodality treatment for locally advanced (T3-4) larynx, hypopharynx and cervical esophageal disease. ( 25202116 )
2014
37
Diet and esophageal disease. ( 25266021 )
2014
38
Esophageal diseases. ( 25127938 )
2014
39
Esophageal diseases. ( 25133481 )
2014
40
Role of robotic-assisted surgery in benign esophageal diseases. ( 27637519 )
2014
41
Eosinophilic esophagitis: an immune-mediated esophageal disease. ( 23579771 )
2013
42
Esophageal disease. ( 23948187 )
2013
43
Esophageal disease. ( 23990483 )
2013
44
Screening pre-bariatric surgery patients for esophageal disease with esophageal capsule endoscopy. ( 24115815 )
2013
45
Innovative techniques in evaluating the esophagus; imaging of esophageal morphology and function; and drugs for esophageal disease. ( 24117631 )
2013
46
Safety of endoscopic removal of self-expandable stents after treatment of benign esophageal diseases. ( 23261092 )
2013
47
Benign and malignant esophageal diseases. ( 23452639 )
2013
48
Research advances in esophageal diseases: bench to bedside. ( 24167725 )
2013
49
New progress in endoscopic treatment of esophageal diseases. ( 24222940 )
2013
50
Redo laparoscopic repair of benign esophageal disease. ( 22608677 )
2012

Variations for Esophageal Disease

Expression for Esophageal Disease

Search GEO for disease gene expression data for Esophageal Disease.

Pathways for Esophageal Disease

GO Terms for Esophageal Disease

Biological processes related to Esophageal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.77 ALB CEACAM5 PDPN PTGS2 TP53
2 cellular sodium ion homeostasis GO:0006883 9.4 ATP12A ATP4A
3 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.32 ATP12A ATP4A
4 cellular potassium ion homeostasis GO:0030007 9.26 ATP12A ATP4A
5 sodium ion export across plasma membrane GO:0036376 9.16 ATP12A ATP4A
6 ethanol oxidation GO:0006069 8.96 ADH1B ALDH2
7 mitotic G1 DNA damage checkpoint GO:0031571 8.62 CCND1 TP53

Molecular functions related to Esophageal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chaperone binding GO:0051087 9.33 ALB PDPN TP53
2 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Esophageal Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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