MCID: ESP001
MIFTS: 34

Esophageal Tuberculosis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Esophageal Tuberculosis

MalaCards integrated aliases for Esophageal Tuberculosis:

Name: Esophageal Tuberculosis 12 15
Tuberculosis of Esophagus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7332
ICD9CM 34 017.8
SNOMED-CT 67 15284007
UMLS 71 C0152902

Summaries for Esophageal Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves formation of tuberculous ulcers located in esophagus. The infection has symptom dysphagia, has symptom cough, has symptom chest pain, has symptom fever and has symptom weight loss.

MalaCards based summary : Esophageal Tuberculosis, also known as tuberculosis of esophagus, is related to mediastinitis and intestinal obstruction, and has symptoms including fever, dysphagia and weight loss. An important gene associated with Esophageal Tuberculosis is CTDP1 (CTD Phosphatase Subunit 1), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic cell lineage. Affiliated tissues include esophagus and lymph node, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Esophageal Tuberculosis

Diseases related to Esophageal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 165)
# Related Disease Score Top Affiliating Genes
1 mediastinitis 29.9 ATP4A ATP12A
2 intestinal obstruction 29.5 MTOR CEACAM5 ATP4A ATP12A
3 acquired immunodeficiency syndrome 29.2 TNFRSF1B IL2RA CR2 CD163
4 mycobacterium tuberculosis 1 10.6
5 dysphagia 10.6
6 vagus nerve disease 10.5 ATP4A ATP12A
7 hemangioma of intra-abdominal structure 10.5 ATP4A ATP12A
8 acquired gastric outlet stenosis 10.5 ATP4A ATP12A
9 displacement of cardia through esophageal hiatus 10.5 ATP4A ATP12A
10 angiodysplasia of intestine 10.5 ATP4A ATP12A
11 lingual goiter 10.5 ATP4A ATP12A
12 cascade stomach 10.5 ATP4A ATP12A
13 gastrojejunal ulcer 10.5 ATP4A ATP12A
14 median arcuate ligament syndrome 10.5 ATP4A ATP12A
15 laryngeal tuberculosis 10.5 ATP4A ATP12A
16 fungal esophagitis 10.5 ATP4A ATP12A
17 dieulafoy lesion 10.5 ATP4A ATP12A
18 esophagus melanoma 10.5 ATP4A ATP12A
19 emphysematous cholecystitis 10.5 ATP4A ATP12A
20 necrotizing gastritis 10.5 ATP4A ATP12A
21 cervix erosion 10.5 ATP4A ATP12A
22 pneumatosis cystoides intestinalis 10.5 ATP4A ATP12A
23 gastric gastrinoma 10.5 ATP4A ATP12A
24 superior mesenteric artery syndrome 10.5 ATP4A ATP12A
25 chronic laryngitis 10.4 ATP4A ATP12A
26 cefuroxime allergy 10.4 ATP4A ATP12A
27 polyposis, skin pigmentation, alopecia, and fingernail changes 10.4 ATP4A ATP12A
28 fox-fordyce disease 10.4 CEACAM5 CD68
29 chronic intestinal vascular insufficiency 10.4 ATP4A ATP12A
30 peptic ulcer perforation 10.4 ATP4A ATP12A
31 rumination disorder 10.4 ATP4A ATP12A
32 blind loop syndrome 10.4 ATP4A ATP12A
33 acute laryngitis 10.4 ATP4A ATP12A
34 t-cell/histiocyte rich large b cell lymphoma 10.4 CR2 CD68
35 gastroduodenitis 10.4 ATP4A ATP12A
36 duodenal gastrinoma 10.4 ATP4A ATP12A
37 gastric hemangioma 10.4 ATP4A ATP12A
38 internal hemorrhoid 10.4 ATP4A ATP12A
39 pancreatic gastrinoma 10.4 ATP4A ATP12A
40 gastric dilatation 10.4 ATP4A ATP12A
41 scalp dermatosis 10.4 ATP4A ATP12A
42 central nervous system origin vertigo 10.4 ATP4A ATP12A
43 diclofenac allergy 10.4 ATP4A ATP12A
44 pericardium disease 10.4 TNFRSF1B IL4I1 CD68
45 myoblastoma 10.4 CEACAM5 CD68
46 liver leiomyoma 10.4 CR2 CEACAM5
47 interdigitating dendritic cell sarcoma 10.4 CR2 CD68
48 lymphocytic gastritis 10.4 ATP4A ATP12A
49 lymphohistiocytoid mesothelioma 10.4 CEACAM5 CD68
50 x-linked chondrodysplasia punctata 1 10.4 ATP4A ATP12A

Graphical network of the top 20 diseases related to Esophageal Tuberculosis:



Diseases related to Esophageal Tuberculosis

Symptoms & Phenotypes for Esophageal Tuberculosis

Symptoms:

12
  • fever
  • dysphagia
  • weight loss
  • cough
  • chest pain

GenomeRNAi Phenotypes related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

26 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-1 9.7 MTOR
2 Decreased viability GR00055-A-2 9.7 MTOR
3 Decreased viability GR00221-A-1 9.7 MTOR
4 Decreased viability GR00221-A-4 9.7 MTOR
5 Decreased viability GR00240-S-1 9.7 PDPN
6 Decreased viability GR00249-S 9.7 ATP12A ATP4A CD163 IL2RA IL4I1 MSH6
7 Decreased viability GR00342-S-1 9.7 MTOR
8 Decreased viability GR00342-S-2 9.7 MTOR
9 Decreased viability GR00381-A-1 9.7 CD163
10 Decreased viability GR00381-A-2 9.7 CD163
11 Decreased viability GR00381-A-3 9.7 CD163
12 Decreased viability GR00386-A-1 9.7 CYGB NFKB1
13 Decreased viability GR00402-S-2 9.7 CD163 IL11 IL2RA NFKB1 PDPN TNFRSF1B

MGI Mouse Phenotypes related to Esophageal Tuberculosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.07 ATP4A CD163 CD68 CR2 CTLA4 IL2RA
2 homeostasis/metabolism MP:0005376 10.06 ATP12A ATP4A CD163 CR2 CTLA4 CYGB
3 digestive/alimentary MP:0005381 9.97 ATP12A ATP4A CTLA4 IL2RA LRBA NFKB1
4 immune system MP:0005387 9.77 ATP4A CD163 CD68 CR2 CTLA4 IL2RA
5 respiratory system MP:0005388 9.17 CD163 CTLA4 IL2RA MTOR NFKB1 PDPN

Drugs & Therapeutics for Esophageal Tuberculosis

Search Clinical Trials , NIH Clinical Center for Esophageal Tuberculosis

Genetic Tests for Esophageal Tuberculosis

Anatomical Context for Esophageal Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Esophageal Tuberculosis:

19
Esophagus

MalaCards organs/tissues related to Esophageal Tuberculosis:

40
Lymph Node

Publications for Esophageal Tuberculosis

Articles related to Esophageal Tuberculosis:

(show top 50) (show all 136)
# Title Authors PMID Year
1
Esophageal tuberculosis mimicking malignancy on 18F-FDG PET/CT. 61
32273239 2020
2
Esophageal Tuberculosis - A Mass of Confusion. 61
32272102 2020
3
Esophageal tuberculosis complicated with intestinal tuberculosis: A case report. 61
32110678 2020
4
Primary Esophageal Tuberculosis Without Dysphagia or Odynophagia in a Patient Without HIV. 61
32440526 2020
5
Esophageal tuberculosis: A rare case report. 61
31793516 2019
6
Primary esophageal tuberculosis mimicking esophageal carcinoma on computed tomography: A case report. 61
31572563 2019
7
Esophageal tuberculosis in an HIV-positive patient mimicking a spindle cell tumor. 61
31213262 2019
8
Bronchoesophageal Fistula due to Esophageal Tuberculosis. 61
31019816 2019
9
Esophageal tuberculosis: a cause of dysphagia we should be aware of. 61
30036504 2018
10
Tuberculous Paraspinal Abscess Invading Esophagus: A Rare Cause of Dysphagia. 61
29950266 2018
11
Esophageal tuberculosis: Uncommon of common. 61
30483561 2018
12
A case of esophageal tuberculosis with unusual endoscopic feature. 61
28578936 2018
13
Rare esophageal ulcers related to Behçet disease: A case report. 61
29095300 2017
14
Tuberculosis of the esophagus. 61
29040488 2017
15
Lymphoepithelioma-Like Carcinoma of the Esophagus: A Rare Tumor. 61
28969745 2017
16
Endoscopic ultrasound in diagnosis of esophageal tuberculosis: 10-year experience at a tertiary care center. 61
28575247 2017
17
Dysphagia from esophageal tuberculosis in a patient with undiagnosed HIV infection. 61
28614889 2017
18
Endosonographic features of esophageal tuberculosis presenting as a subepithelial lesion. 61
28139030 2017
19
Esophageal tuberculosis with coexisting opportunistic infections in a renal allograft transplant recipient. 61
27885762 2017
20
A case report on esophageal tuberculosis - A rare entity. 61
28437671 2017
21
Esophageal tuberculosis: A rather specific endoscopic lesion? 61
27339597 2016
22
Primary esophageal tuberculosis mimicking esophageal cancer with vascular involvement. 61
26879170 2016
23
Esophageal tuberculosis initially misdiagnosed by endoscopy as a submucosal tumor. 61
25603515 2015
24
[A case of esophageal and intestinal tuberculosis that occurred during treatment of rheumatoid arthritis with etanercept]. 61
25283012 2014
25
Esophageal tuberculosis during treatment of hepatitis C. 61
23639604 2013
26
Esophageal tuberculosis presenting with hematemesis. 61
24255751 2013
27
[Esophagobronchial fistula as an end complication of esophageal tuberculosis]. 61
24051187 2013
28
Surgical outcome of esophageal tuberculosis secondary to mediastinal lymphadenitis in adults: experience from single center in China. 61
23991308 2013
29
Esophageal Tuberculosis Presenting As Dysphagia. 61
31440354 2013
30
Endosonography and elastography in the diagnosis of esophageal tuberculosis. 61
24226724 2013
31
Esophageal tuberculosis. 61
22521125 2012
32
[Oral blastomycosis, laryngeal papillomatosis and esophageal tuberculosis]. 61
22858774 2012
33
Esophageal tuberculosis: EUS FNA diagnosis of uncommon presentation as a cystic lesion. 61
21538949 2012
34
Esophageal tuberculosis: role of endoscopic ultrasound in diagnosis. 61
21777339 2012
35
Esophageal tuberculosis mimicking submucosal leiomyoma- report of a case. 61
23204713 2011
36
Dysphagia as a manifestation of esophageal tuberculosis: a report of two cases. 61
21902828 2011
37
[Esophageal tuberculosis: case report and review of the literature]. 61
21539068 2011
38
Esophageal tuberculosis: a microgranuloma visualized by narrow-band imaging magnifying endoscopy. 61
21971928 2011
39
Endoscopic findings and clinical features of esophageal tuberculosis. 61
20568972 2010
40
An unusual cause of dysphagia: esophageal tuberculosis. 61
20922199 2010
41
Esophageal tuberculosis: an unusual cause of dysphagia. 61
19152888 2009
42
Esophageal tuberculosis in a patient on maintenance dialysis: advantages of interferon-gamma release assay. 61
19288332 2009
43
Endoscopic ultrasonography in esophageal tuberculosis. 61
18680081 2008
44
Unusual presentation of esophageal tuberculosis mimicking malignancy. 61
19568514 2008
45
Esophageal tuberculosis presenting as a submucosal tumor. 61
18237860 2008
46
[Esophageal tuberculosis. report of one case with AIDS]. 61
18180841 2007
47
An unusual case of dysphagia and chest pain in a non-HIV patient: esophageal tuberculosis. 61
17398209 2007
48
Esophageal tuberculosis. 61
17611894 2007
49
Value of endoscopic ultrasonography for diagnosis of esophageal tuberculosis: report of two cases. 61
16927151 2006
50
[Esophageal tuberculosis]. 61
16865167 2006

Variations for Esophageal Tuberculosis

Expression for Esophageal Tuberculosis

Search GEO for disease gene expression data for Esophageal Tuberculosis.

Pathways for Esophageal Tuberculosis

GO Terms for Esophageal Tuberculosis

Cellular components related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mismatch repair complex GO:0032300 8.62 PMS2 MSH6

Biological processes related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of regulatory T cell differentiation GO:0045589 9.43 IL2RA CTLA4
2 somatic hypermutation of immunoglobulin genes GO:0016446 9.4 PMS2 MSH6
3 negative regulation of immune response GO:0050777 9.37 IL2RA CTLA4
4 sodium ion export across plasma membrane GO:0036376 9.32 ATP4A ATP12A
5 cellular response to nutrient levels GO:0031669 9.26 MTOR CD68
6 cellular potassium ion homeostasis GO:0030007 9.16 ATP4A ATP12A
7 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.96 ATP4A ATP12A
8 regulation of T cell proliferation GO:0042129 8.62 TNFRSF1B CTLA4

Molecular functions related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mismatched DNA binding GO:0030983 9.26 PMS2 MSH6
2 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
3 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
4 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Esophageal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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