MCID: ESP001
MIFTS: 32

Esophageal Tuberculosis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Esophageal Tuberculosis

MalaCards integrated aliases for Esophageal Tuberculosis:

Name: Esophageal Tuberculosis 12 15
Tuberculosis of Esophagus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7332
ICD9CM 34 017.8
SNOMED-CT 67 15284007
UMLS 71 C0152902

Summaries for Esophageal Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves formation of tuberculous ulcers located in esophagus. The infection has symptom dysphagia, has symptom cough, has symptom chest pain, has symptom fever and has symptom weight loss.

MalaCards based summary : Esophageal Tuberculosis, also known as tuberculosis of esophagus, is related to aspiration pneumonia and mediastinitis, and has symptoms including dysphagia, fever and weight loss. An important gene associated with Esophageal Tuberculosis is CTDP1 (CTD Phosphatase Subunit 1), and among its related pathways/superpathways is Inflammatory Response Pathway. Affiliated tissues include esophagus, bone and lymph node, and related phenotypes are homeostasis/metabolism and immune system

Related Diseases for Esophageal Tuberculosis

Diseases related to Esophageal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 228)
# Related Disease Score Top Affiliating Genes
1 aspiration pneumonia 29.3 CRP ATP4A ATP12A
2 mediastinitis 29.1 CRP ATP4A ATP12A
3 intestinal obstruction 28.4 SST CRP ATP4A ATP12A
4 mycobacterium tuberculosis 1 10.6
5 dysphagia 10.5
6 orbital plasma cell granuloma 10.4 TNFRSF1B CRP
7 rheumatoid arthritis interstitial lung disease 10.4 TNFRSF1B CRP
8 chronic orbital inflammation 10.4 TNFRSF1B CRP
9 anterior scleritis 10.4 TNFRSF1B CRP
10 scleritis 10.4 TNFRSF1B CRP
11 optic papillitis 10.4 TNFRSF1B CRP
12 granulomatous hepatitis 10.4 TNFRSF1B CRP
13 opportunistic bacterial infectious disease 10.4 TNFRSF1B CRP
14 wissler's syndrome 10.4 TNFRSF1B CRP
15 nocardiosis 10.4 TNFRSF1B CRP
16 neurosarcoidosis 10.4 TNFRSF1B CRP
17 mononeuritis of upper limb and mononeuritis multiplex 10.4 TNFRSF1B CRP
18 mononeuritis multiplex 10.4 TNFRSF1B CRP
19 aortitis 10.4 TNFRSF1B CRP
20 hypopyon 10.4 TNFRSF1B CRP
21 tenosynovitis 10.4 TNFRSF1B CRP
22 chondromalacia 10.4 TNFRSF1B CRP
23 scleral disease 10.4 TNFRSF1B CRP
24 bursitis 10.4 TNFRSF1B CRP
25 good syndrome 10.3 TNFRSF1B CRP
26 iritis 10.3 TNFRSF1B CRP
27 miliary tuberculosis 10.3 TNFRSF1B CRP
28 gallbladder small cell carcinoma 10.3 SPINK5 CRP
29 enthesopathy 10.3 TNFRSF1B CRP
30 iridocyclitis 10.3 TNFRSF1B CRP
31 mononeuropathy 10.3 TNFRSF1B CRP
32 tendinitis 10.3 TNFRSF1B CRP
33 polyradiculopathy 10.3 TNFRSF1B CRP
34 nasopharyngitis 10.3 TNFRSF1B CRP
35 meckel diverticulum 10.3 SPINK5 CRP
36 cartilage disease 10.3 TNFRSF1B CRP
37 primary systemic mycosis 10.3 TNFRSF1B CRP
38 pneumocystosis 10.3 TNFRSF1B CRP
39 necrobiosis lipoidica 10.3 TNFRSF1B CD68
40 granuloma annulare 10.3 TNFRSF1B CD68
41 lymphangitis 10.3 CRP ALK
42 autoimmune disease of cardiovascular system 10.2 SPINK5 CD28
43 granulomatous dermatitis 10.2 TNFRSF1B CD68
44 uveoparotid fever 10.2 TNFRSF1B CD68
45 cat-scratch disease 10.2 CRP CD68
46 esophageal cancer 10.2
47 bartonellosis 10.2 CRP CD68
48 necrotizing fasciitis 10.2 SPINK5 CRP
49 petrositis 10.2 SST CRP
50 whipple disease 10.2 CRP CD68

Graphical network of the top 20 diseases related to Esophageal Tuberculosis:



Diseases related to Esophageal Tuberculosis

Symptoms & Phenotypes for Esophageal Tuberculosis

Symptoms:

12
  • dysphagia
  • fever
  • weight loss
  • cough
  • chest pain

MGI Mouse Phenotypes related to Esophageal Tuberculosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.61 ALK ARG1 ATP12A ATP4A CD28 CRP
2 immune system MP:0005387 9.23 ARG1 ATP4A CD28 CD68 CRP SPINK5

Drugs & Therapeutics for Esophageal Tuberculosis

Search Clinical Trials , NIH Clinical Center for Esophageal Tuberculosis

Genetic Tests for Esophageal Tuberculosis

Anatomical Context for Esophageal Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Esophageal Tuberculosis:

19
Esophagus

MalaCards organs/tissues related to Esophageal Tuberculosis:

40
Bone, Lymph Node, Heart, Small Intestine, Lung, Thyroid, Skin

Publications for Esophageal Tuberculosis

Articles related to Esophageal Tuberculosis:

(show top 50) (show all 132)
# Title Authors PMID Year
1
Esophageal tuberculosis: A rare case report. 61
31793516 2019
2
Primary esophageal tuberculosis mimicking esophageal carcinoma on computed tomography: A case report. 61
31572563 2019
3
Esophageal tuberculosis in an HIV-positive patient mimicking a spindle cell tumor. 61
31213262 2019
4
Bronchoesophageal Fistula due to Esophageal Tuberculosis. 61
31019816 2019
5
Esophageal tuberculosis: a cause of dysphagia we should be aware of. 61
30036504 2018
6
Tuberculous Paraspinal Abscess Invading Esophagus: A Rare Cause of Dysphagia. 61
29950266 2018
7
Esophageal tuberculosis: Uncommon of common. 61
30483561 2018
8
A case of esophageal tuberculosis with unusual endoscopic feature. 61
28578936 2018
9
Rare esophageal ulcers related to Behçet disease: A case report. 61
29095300 2017
10
Tuberculosis of the esophagus. 61
29040488 2017
11
Lymphoepithelioma-Like Carcinoma of the Esophagus: A Rare Tumor. 61
28969745 2017
12
Endoscopic ultrasound in diagnosis of esophageal tuberculosis: 10-year experience at a tertiary care center. 61
28575247 2017
13
Dysphagia from esophageal tuberculosis in a patient with undiagnosed HIV infection. 61
28614889 2017
14
Endosonographic features of esophageal tuberculosis presenting as a subepithelial lesion. 61
28139030 2017
15
Esophageal tuberculosis with coexisting opportunistic infections in a renal allograft transplant recipient. 61
27885762 2017
16
A case report on esophageal tuberculosis - A rare entity. 61
28437671 2017
17
Esophageal tuberculosis: A rather specific endoscopic lesion? 61
27339597 2016
18
Primary esophageal tuberculosis mimicking esophageal cancer with vascular involvement. 61
26879170 2016
19
Esophageal tuberculosis initially misdiagnosed by endoscopy as a submucosal tumor. 61
25603515 2015
20
[A case of esophageal and intestinal tuberculosis that occurred during treatment of rheumatoid arthritis with etanercept]. 61
25283012 2014
21
Esophageal tuberculosis during treatment of hepatitis C. 61
23639604 2013
22
Esophageal tuberculosis presenting with hematemesis. 61
24255751 2013
23
[Esophagobronchial fistula as an end complication of esophageal tuberculosis]. 61
24051187 2013
24
Surgical outcome of esophageal tuberculosis secondary to mediastinal lymphadenitis in adults: experience from single center in China. 61
23991308 2013
25
Esophageal Tuberculosis Presenting As Dysphagia. 61
31440354 2013
26
Endosonography and elastography in the diagnosis of esophageal tuberculosis. 61
24226724 2013
27
Esophageal tuberculosis. 61
22521125 2012
28
[Oral blastomycosis, laryngeal papillomatosis and esophageal tuberculosis]. 61
22858774 2012
29
Esophageal tuberculosis: EUS FNA diagnosis of uncommon presentation as a cystic lesion. 61
21538949 2012
30
Esophageal tuberculosis: role of endoscopic ultrasound in diagnosis. 61
21777339 2012
31
Esophageal tuberculosis mimicking submucosal leiomyoma- report of a case. 61
23204713 2011
32
Dysphagia as a manifestation of esophageal tuberculosis: a report of two cases. 61
21902828 2011
33
[Esophageal tuberculosis: case report and review of the literature]. 61
21539068 2011
34
Esophageal tuberculosis: a microgranuloma visualized by narrow-band imaging magnifying endoscopy. 61
21971928 2011
35
Endoscopic findings and clinical features of esophageal tuberculosis. 61
20568972 2010
36
An unusual cause of dysphagia: esophageal tuberculosis. 61
20922199 2010
37
Esophageal tuberculosis: an unusual cause of dysphagia. 61
19152888 2009
38
Esophageal tuberculosis in a patient on maintenance dialysis: advantages of interferon-gamma release assay. 61
19288332 2009
39
Endoscopic ultrasonography in esophageal tuberculosis. 61
18680081 2008
40
Unusual presentation of esophageal tuberculosis mimicking malignancy. 61
19568514 2008
41
Esophageal tuberculosis presenting as a submucosal tumor. 61
18237860 2008
42
[Esophageal tuberculosis. report of one case with AIDS]. 61
18180841 2007
43
An unusual case of dysphagia and chest pain in a non-HIV patient: esophageal tuberculosis. 61
17398209 2007
44
Esophageal tuberculosis. 61
17611894 2007
45
Value of endoscopic ultrasonography for diagnosis of esophageal tuberculosis: report of two cases. 61
16927151 2006
46
[Esophageal tuberculosis]. 61
16865167 2006
47
Esophageal tuberculosis in a patient with acquired immune deficiency syndrome: a rare presentation. 61
17366393 2006
48
[A case of esophageal tuberculosis which developed during the treatment for tuberculous lymphadenitis]. 61
16167780 2005
49
Esophageal tuberculosis mimicking esophageal carcinoma. 61
16252203 2005
50
[Secondary esophageal tuberculosis]. 61
15839816 2005

Variations for Esophageal Tuberculosis

Expression for Esophageal Tuberculosis

Search GEO for disease gene expression data for Esophageal Tuberculosis.

Pathways for Esophageal Tuberculosis

Pathways related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.14 TNFRSF1B CD28

GO Terms for Esophageal Tuberculosis

Biological processes related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.58 TNFRSF1B CD68 ARG1
2 cellular response to lipopolysaccharide GO:0071222 9.54 TNFRSF1B CD68 ARG1
3 response to amino acid GO:0043200 9.46 SST ARG1
4 response to steroid hormone GO:0048545 9.43 SST ARG1
5 cellular sodium ion homeostasis GO:0006883 9.32 ATP4A ATP12A
6 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.26 ATP4A ATP12A
7 regulation of T cell proliferation GO:0042129 9.16 TNFRSF1B CD28
8 sodium ion export across plasma membrane GO:0036376 8.96 ATP4A ATP12A
9 cellular potassium ion homeostasis GO:0030007 8.62 ATP4A ATP12A

Molecular functions related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Esophageal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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