MCID: ESP001
MIFTS: 32

Esophageal Tuberculosis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Esophageal Tuberculosis

MalaCards integrated aliases for Esophageal Tuberculosis:

Name: Esophageal Tuberculosis 12 15
Tuberculosis of Esophagus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7332
ICD9CM 34 017.8
SNOMED-CT 67 15284007
UMLS 70 C0152902

Summaries for Esophageal Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves formation of tuberculous ulcers located in esophagus. The infection has symptom dysphagia, has symptom cough, has symptom chest pain, has symptom fever and has symptom weight loss.

MalaCards based summary : Esophageal Tuberculosis, also known as tuberculosis of esophagus, is related to mediastinitis and intestinal obstruction, and has symptoms including dysphagia, fever and cough. An important gene associated with Esophageal Tuberculosis is CTDP1 (CTD Phosphatase Subunit 1), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic cell lineage. Affiliated tissues include esophagus and lymph node, and related phenotypes are digestive/alimentary and hematopoietic system

Related Diseases for Esophageal Tuberculosis

Diseases related to Esophageal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 204)
# Related Disease Score Top Affiliating Genes
1 mediastinitis 30.1 ATP4A ATP12A
2 intestinal obstruction 29.8 CEACAM5 ATP4A ATP12A
3 esophageal disease 29.7 CEACAM5 ATP4A ATP12A
4 acquired immunodeficiency syndrome 29.4 IL2RA CR2 CD163
5 dysphagia 10.6
6 mycobacterium tuberculosis 1 10.4
7 vagus nerve disease 10.3 ATP4A ATP12A
8 necrotizing gastritis 10.3 ATP4A ATP12A
9 scalp dermatosis 10.3 ATP4A ATP12A
10 hemangioma of intra-abdominal structure 10.3 ATP4A ATP12A
11 acquired gastric outlet stenosis 10.3 ATP4A ATP12A
12 lingual goiter 10.3 ATP4A ATP12A
13 displacement of cardia through esophageal hiatus 10.3 ATP4A ATP12A
14 cascade stomach 10.3 ATP4A ATP12A
15 benzylpenicillin allergy 10.3 ATP4A ATP12A
16 median arcuate ligament syndrome 10.3 ATP4A ATP12A
17 afferent loop syndrome 10.3 ATP4A ATP12A
18 cervix erosion 10.3 ATP4A ATP12A
19 angiodysplasia of intestine 10.3 ATP4A ATP12A
20 angiodysplasia 10.3 ATP4A ATP12A
21 fungal esophagitis 10.3 ATP4A ATP12A
22 dieulafoy lesion 10.3 ATP4A ATP12A
23 esophagus melanoma 10.3 ATP4A ATP12A
24 cefuroxime allergy 10.3 ATP4A ATP12A
25 emphysematous cholecystitis 10.3 ATP4A ATP12A
26 gastric gastrinoma 10.3 ATP4A ATP12A
27 superior mesenteric artery syndrome 10.3 ATP4A ATP12A
28 pneumatosis cystoides intestinalis 10.3 ATP4A ATP12A
29 chronic laryngitis 10.3 ATP4A ATP12A
30 laryngitis 10.3 ATP4A ATP12A
31 peptic ulcer perforation 10.3 ATP4A ATP12A
32 viral laryngitis 10.3 ATP4A ATP12A
33 gastroduodenal crohn's disease 10.3 ATP4A ATP12A
34 polyposis, skin pigmentation, alopecia, and fingernail changes 10.3 ATP4A ATP12A
35 central nervous system origin vertigo 10.3 ATP4A ATP12A
36 rumination disorder 10.3 ATP4A ATP12A
37 internal hemorrhoid 10.3 ATP4A ATP12A
38 acute laryngitis 10.3 ATP4A ATP12A
39 gastroduodenitis 10.3 ATP4A ATP12A
40 duodenitis 10.3 ATP4A ATP12A
41 chronic intestinal vascular insufficiency 10.3 ATP4A ATP12A
42 barbiturate abuse 10.3 ATP4A ATP12A
43 duodenal gastrinoma 10.3 ATP4A ATP12A
44 gastric dilatation 10.3 ATP4A ATP12A
45 gastric hemangioma 10.3 ATP4A ATP12A
46 blind loop syndrome 10.3 ATP4A ATP12A
47 polycystic echinococcosis 10.3 ATP4A ATP12A
48 diclofenac allergy 10.3 ATP4A ATP12A
49 lymphocytic gastritis 10.3 ATP4A ATP12A
50 t-cell/histiocyte rich large b cell lymphoma 10.3 CR2 CD68

Graphical network of the top 20 diseases related to Esophageal Tuberculosis:



Diseases related to Esophageal Tuberculosis

Symptoms & Phenotypes for Esophageal Tuberculosis

Symptoms:

12
  • dysphagia
  • fever
  • cough
  • chest pain
  • weight loss

MGI Mouse Phenotypes related to Esophageal Tuberculosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.7 ATP12A ATP4A CTLA4 IL2RA LRBA NFKB1
2 hematopoietic system MP:0005397 9.65 ATP4A CD163 CD68 CR2 CTLA4 IL2RA
3 immune system MP:0005387 9.32 ATP4A CD163 CD68 CR2 CTLA4 IL2RA

Drugs & Therapeutics for Esophageal Tuberculosis

Search Clinical Trials , NIH Clinical Center for Esophageal Tuberculosis

Genetic Tests for Esophageal Tuberculosis

Anatomical Context for Esophageal Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Esophageal Tuberculosis:

19
Esophagus

MalaCards organs/tissues related to Esophageal Tuberculosis:

40
Lymph Node

Publications for Esophageal Tuberculosis

Articles related to Esophageal Tuberculosis:

(show top 50) (show all 141)
# Title Authors PMID Year
1
Spontaneous perforation as a fatal presentation of esophageal tuberculosis: A case report. 61
33360335 2021
2
Clinical and endoscopic features of esophageal tuberculosis: a 20-year retrospective study. 61
32881605 2020
3
Esophageal Tuberculosis - A Mass of Confusion. 61
32272102 2020
4
EUS in the diagnosis of pathologically undiagnosed esophageal tuberculosis. 61
32859167 2020
5
"Esophagomediastinal fistula presenting as drug resistant tuberculosis". 61
32825869 2020
6
Esophageal tuberculosis mimicking malignancy on 18F-FDG PET/CT. 61
32273239 2020
7
Primary Esophageal Tuberculosis Without Dysphagia or Odynophagia in a Patient Without HIV. 61
32440526 2020
8
Esophageal tuberculosis complicated with intestinal tuberculosis: A case report. 61
32110678 2020
9
Esophageal tuberculosis: A rare case report. 61
31793516 2019
10
Primary esophageal tuberculosis mimicking esophageal carcinoma on computed tomography: A case report. 61
31572563 2019
11
Esophageal tuberculosis in an HIV-positive patient mimicking a spindle cell tumor. 61
31213262 2019
12
Bronchoesophageal Fistula due to Esophageal Tuberculosis. 61
31019816 2019
13
Esophageal tuberculosis: a cause of dysphagia we should be aware of. 61
30036504 2018
14
Tuberculous Paraspinal Abscess Invading Esophagus: A Rare Cause of Dysphagia. 61
29950266 2018
15
Esophageal tuberculosis: Uncommon of common. 61
30483561 2018
16
A case of esophageal tuberculosis with unusual endoscopic feature. 61
28578936 2018
17
Tuberculosis of the esophagus. 61
29040488 2017
18
Rare esophageal ulcers related to Behçet disease: A case report. 61
29095300 2017
19
Lymphoepithelioma-Like Carcinoma of the Esophagus: A Rare Tumor. 61
28969745 2017
20
Endoscopic ultrasound in diagnosis of esophageal tuberculosis: 10-year experience at a tertiary care center. 61
28575247 2017
21
Dysphagia from esophageal tuberculosis in a patient with undiagnosed HIV infection. 61
28614889 2017
22
Endosonographic features of esophageal tuberculosis presenting as a subepithelial lesion. 61
28139030 2017
23
Esophageal tuberculosis with coexisting opportunistic infections in a renal allograft transplant recipient. 61
27885762 2017
24
A case report on esophageal tuberculosis - A rare entity. 61
28437671 2017
25
Esophageal tuberculosis: A rather specific endoscopic lesion? 61
27339597 2016
26
Primary esophageal tuberculosis mimicking esophageal cancer with vascular involvement. 61
26879170 2016
27
Esophageal tuberculosis initially misdiagnosed by endoscopy as a submucosal tumor. 61
25603515 2015
28
[A case of esophageal and intestinal tuberculosis that occurred during treatment of rheumatoid arthritis with etanercept]. 61
25283012 2014
29
Esophageal tuberculosis during treatment of hepatitis C. 61
23639604 2013
30
Esophageal tuberculosis presenting with hematemesis. 61
24255751 2013
31
[Esophagobronchial fistula as an end complication of esophageal tuberculosis]. 61
24051187 2013
32
Surgical outcome of esophageal tuberculosis secondary to mediastinal lymphadenitis in adults: experience from single center in China. 61
23991308 2013
33
Esophageal Tuberculosis Presenting As Dysphagia. 61
31440354 2013
34
Endosonography and elastography in the diagnosis of esophageal tuberculosis. 61
24226724 2013
35
Esophageal tuberculosis. 61
22521125 2012
36
[Oral blastomycosis, laryngeal papillomatosis and esophageal tuberculosis]. 61
22858774 2012
37
Esophageal tuberculosis: EUS FNA diagnosis of uncommon presentation as a cystic lesion. 61
21538949 2012
38
Esophageal tuberculosis: role of endoscopic ultrasound in diagnosis. 61
21777339 2012
39
Esophageal tuberculosis mimicking submucosal leiomyoma- report of a case. 61
23204713 2011
40
Dysphagia as a manifestation of esophageal tuberculosis: a report of two cases. 61
21902828 2011
41
[Esophageal tuberculosis: case report and review of the literature]. 61
21539068 2011
42
Esophageal tuberculosis: a microgranuloma visualized by narrow-band imaging magnifying endoscopy. 61
21971928 2011
43
Endoscopic findings and clinical features of esophageal tuberculosis. 61
20568972 2010
44
An unusual cause of dysphagia: esophageal tuberculosis. 61
20922199 2010
45
Esophageal tuberculosis: an unusual cause of dysphagia. 61
19152888 2009
46
Esophageal tuberculosis in a patient on maintenance dialysis: advantages of interferon-gamma release assay. 61
19288332 2009
47
Endoscopic ultrasonography in esophageal tuberculosis. 61
18680081 2008
48
Unusual presentation of esophageal tuberculosis mimicking malignancy. 61
19568514 2008
49
Esophageal tuberculosis presenting as a submucosal tumor. 61
18237860 2008
50
[Esophageal tuberculosis. report of one case with AIDS]. 61
18180841 2007

Variations for Esophageal Tuberculosis

Expression for Esophageal Tuberculosis

Search GEO for disease gene expression data for Esophageal Tuberculosis.

Pathways for Esophageal Tuberculosis

Pathways related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.07 NFKB1 IL2RA CTLA4 CEACAM5
2 11.33 IL2RA IL11 CR2
3 11.09 IL2RA IL11 CEACAM5 CD68 CD163
4 11.08 NFKB1 IL2RA CTLA4 CR2

GO Terms for Esophageal Tuberculosis

Cellular components related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.65 PMS2 LRBA IL2RA CTLA4 CR2 CEACAM5
2 mismatch repair complex GO:0032300 8.62 PMS2 MSH6

Biological processes related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response to antigenic stimulus GO:0002437 9.43 IL2RA CD68
2 cellular sodium ion homeostasis GO:0006883 9.4 ATP4A ATP12A
3 regulation of regulatory T cell differentiation GO:0045589 9.37 IL2RA CTLA4
4 somatic hypermutation of immunoglobulin genes GO:0016446 9.32 PMS2 MSH6
5 negative regulation of immune response GO:0050777 9.26 IL2RA CTLA4
6 sodium ion export across plasma membrane GO:0036376 9.16 ATP4A ATP12A
7 cellular potassium ion homeostasis GO:0030007 8.96 ATP4A ATP12A
8 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP4A ATP12A

Molecular functions related to Esophageal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mismatched DNA binding GO:0030983 9.26 PMS2 MSH6
2 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
3 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
4 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Esophageal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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