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MCID: ESP002
MIFTS: 50

Esophageal Varix

Categories: Cardiovascular diseases, Gastrointestinal diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Esophageal Varix

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MalaCards integrated aliases for Esophageal Varix:

Name: Esophageal Varix 12 29 15
Esophageal Varices 12 76 53 55 15
Bleeding Esophageal Varices 12 55 73
Esophageal Varices in Disease Classified Elsewhere, with Bleeding 12
Esophageal Varices with Bleeding in Disease Ec 12
Esophageal Varices Without Mention of Bleeding 12
Esophageal Varices Without Bleeding 12
Esophageal Varices with Bleeding 12
Bleeding Oesophageal Varices 12

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Gastrointestinal diseases Cardiovascular diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:112
ICD10 33 I85.01
ICD9CM 35 456.0 456.2 456.20
NCIt 50 C78282
SNOMED-CT 68 17709002
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Summaries for Esophageal Varix

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MalaCards based summary : Esophageal Varix, also known as esophageal varices, is related to portal hypertension and alcoholic liver cirrhosis. An important gene associated with Esophageal Varix is SST (Somatostatin), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. The drugs Propranolol and AT-101 have been mentioned in the context of this disorder. Affiliated tissues include liver, spleen and testes, and related phenotypes are digestive/alimentary and homeostasis/metabolism

Wikipedia : 76 Esophageal varices (sometimes spelled esophageal varix, or oesophageal varices) are extremely dilated... more...

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Related Diseases for Esophageal Varix

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Diseases related to Esophageal Varix via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 261)
# Related Disease Score Top Affiliating Genes
1 portal hypertension 30.8 ALB F2 SST
2 alcoholic liver cirrhosis 30.4 AFP ALB F2
3 hepatic coma 30.3 ALB F2
4 hepatitis b 30.2 AFP ALB F2
5 infantile liver failure syndrome 1 30.1 ALB F2
6 hepatorenal syndrome 30.1 ALB F2
7 esophageal candidiasis 30.0 ATP12A ATP4A
8 duodenitis 30.0 ATP12A ATP4A
9 peptic esophagitis 30.0 ATP12A ATP4A
10 microinvasive gastric cancer 30.0 ATP12A ATP4A
11 liver disease 29.9 AFP ALB F2
12 portal vein thrombosis 29.9 AFP F2 SERPINC1
13 hypersplenism 29.9 ALB F2 SERPINC1
14 liver cirrhosis 29.5 AFP ALB F2 SERPINC1 SST
15 budd-chiari syndrome 11.6
16 cerebroretinal microangiopathy with calcifications and cysts 2 11.3
17 hepatitis c 10.5
18 varicose veins 10.5
19 hepatitis c virus 10.4
20 biliary atresia 10.3
21 primary biliary cholangitis 10.3
22 antipyrine metabolism 10.3 ALB F2
23 non-a-e hepatitis 10.3 ALB F2
24 epstein-barr virus hepatitis 10.3 ALB F2
25 biliary cirrhosis, primary, 1 10.3
26 primary biliary cirrhosis 10.3
27 yellow nail syndrome 10.3 ALB SST
28 abdominal tuberculosis 10.3 ALB F2
29 hepatic tuberculosis 10.2 ALB F2
30 kwashiorkor 10.2 ALB F2
31 chylothorax, congenital 10.2 ALB SST
32 endometrial small cell carcinoma 10.2 AFP F2
33 pancreatoblastoma 10.2 AFP SST
34 vitamin k deficiency hemorrhagic disease 10.2 AFP F2
35 splenic disease 10.2 ALB F2
36 hepatoid adenocarcinoma 10.2 AFP ALB
37 ascending cholangitis 10.2 ALB F2
38 schistosomiasis 10.2
39 drug allergy 10.2 ALB ATP12A
40 endodermal sinus tumor 10.2 AFP ALB
41 compartment syndrome 10.2 ALB F2
42 fungal esophagitis 10.2 ATP12A ATP4A
43 diclofenac allergy 10.2 ATP12A ATP4A
44 gastroduodenal crohn's disease 10.2 ATP12A ATP4A
45 neonatal candidiasis 10.2 ATP12A ATP4A
46 photoallergic dermatitis 10.2 ATP12A ATP4A
47 squamous papillomatosis 10.2 ATP12A ATP4A
48 toxic megacolon 10.2 ATP12A ATP4A
49 aspiration pneumonitis 10.2 ATP12A ATP4A
50 granulomatous gastritis 10.2 ATP12A ATP4A

Comorbidity relations with Esophageal Varix via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Cystitis
Alcoholic Liver Cirrhosis Deficiency Anemia
Esophageal Disease Esophagitis
Heart Disease Hepatic Encephalopathy
Portal Hypertension

Graphical network of the top 20 diseases related to Esophageal Varix:



Diseases related to Esophageal Varix
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Symptoms & Phenotypes for Esophageal Varix

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MGI Mouse Phenotypes related to Esophageal Varix:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.7 ALB ATP12A ATP4A F2 JMJD6 SLC4A4
2 homeostasis/metabolism MP:0005376 9.61 AFP ALB ATP12A ATP4A F2 JMJD6
3 renal/urinary system MP:0005367 9.02 ALB ATP12A JMJD6 SERPINC1 SLC4A4
Sources

Drugs & Therapeutics for Esophageal Varix

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Drugs for Esophageal Varix (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 131)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propranolol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 525-66-6 4946
2
AT-101 Approved, Investigational Phase 4 90141-22-3, 652-67-5 12597
3
Nadolol Approved Phase 4,Phase 3 42200-33-9 39147
4
Prazosin Approved Phase 4 19216-56-9 4893
5
Nitric Oxide Approved Phase 4,Phase 3 10102-43-9 145068
6
Isosorbide Dinitrate Approved, Investigational Phase 4 87-33-2 6883
7
Simvastatin Approved Phase 4,Phase 3,Not Applicable 79902-63-9 54454
8
Carvedilol Approved, Investigational Phase 4,Phase 3,Not Applicable 72956-09-3 2585
9
Somatostatin Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 51110-01-1, 38916-34-6 53481605
10
Lypressin Approved Phase 4,Not Applicable 50-57-7
11
Terlipressin Approved, Investigational Phase 4,Not Applicable 14636-12-5 72081
12
Octreotide Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 83150-76-9 383414 6400441
13
Ethanolamine oleate Approved Phase 4,Phase 3 2272-11-9
14
Ethiodized oil Approved, Investigational Phase 4,Not Applicable 8008-53-5
15
Entecavir Approved, Investigational Phase 4 142217-69-4 153941
16
Tranexamic Acid Approved Phase 4 1197-18-8 5526
17
Telbivudine Approved, Investigational Phase 4 3424-98-4 159269
18
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 11103-57-4, 68-26-8 445354
19
Tenofovir Experimental, Investigational Phase 4 147127-20-6 464205
20 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 3,Not Applicable
21 Adrenergic Agents Phase 4,Phase 2,Phase 3,Not Applicable
22 Antihypertensive Agents Phase 4,Phase 2,Phase 3,Not Applicable
23 Adrenergic beta-Antagonists Phase 4,Phase 2,Phase 3,Not Applicable
24 Adrenergic Antagonists Phase 4,Phase 2,Phase 3,Not Applicable
25 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Not Applicable
26 Vasodilator Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
27 isosorbide-5-mononitrate Phase 4
28 Autonomic Agents Phase 4,Not Applicable
29 Adrenergic alpha-1 Receptor Antagonists Phase 4,Phase 3,Not Applicable
30 Peripheral Nervous System Agents Phase 4,Phase 3,Not Applicable
31 Sympatholytics Phase 4
32 Nitric Oxide Donors Phase 4
33 Adrenergic alpha-Antagonists Phase 4,Phase 3,Not Applicable
34 diuretics Phase 4
35 Natriuretic Agents Phase 4,Not Applicable
36 Hypolipidemic Agents Phase 4,Phase 3,Not Applicable
37 Anticholesteremic Agents Phase 4,Phase 3,Not Applicable
38 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4,Phase 3,Not Applicable
39 Antimetabolites Phase 4,Phase 3,Not Applicable
40 Lipid Regulating Agents Phase 4,Phase 3,Not Applicable
41 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
43 Hormone Antagonists Phase 4,Not Applicable
44 Hormones Phase 4,Not Applicable
45 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Not Applicable
46 Anti-Infective Agents Phase 4,Phase 3,Phase 2
47 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
48 Retinol palmitate Phase 4
49 retinol Phase 4
50 Coagulants Phase 4,Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 138)
# Name Status NCT ID Phase Drugs
1 Preventing Recurrent Bleeding After Eradication of Esophageal Varices Unknown status NCT02740166 Phase 4 propranolol
2 Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices Unknown status NCT01970748 Phase 4 Propranolol
3 Endoscopic Treatment Alone Versus Combined Propranolol and Endoscopic Treatment of Acute Variceal Hemorrhage in Patients With Hepatocellular Carcinoma Unknown status NCT01451658 Phase 4 propranolol
4 Treatment for Prevention of Variceal Rebleeding Guided by the Hemodynamic Response Unknown status NCT00563602 Phase 4
5 Hemodynamic Effect of Simvastatin With Beta Blockers in Clinical Portal Hypertension Unknown status NCT01282385 Phase 4 Simvastatin;placebo
6 PROPRANOLOL PLUS LIGATION REDUCES RECURRENCE OF ESOPHAGEAL VARICES? Completed NCT01893541 Phase 4 PROPRANOLOL
7 Time Interval for Endoscopic Variceal Ligation Completed NCT01291277 Phase 4
8 Hemodynamic Effects of Terlipressin and High Dose Octreotide Completed NCT02119884 Phase 4 Terlipressin;Octreotide
9 A Randomized Controlled Trial Comparing Band Ligation and Cyanoacrylate Injection for Esophageal Varices Completed NCT00799851 Phase 4 cyanoacrylate injection
10 EVL (Endoscopic Variceal Ligation) Plus Vasoconstrictor vs.Ligation Plus PPI( Proton Pump Inhibitor) in the Control of Acute Esophageal Variceal Bleeding Completed NCT01112852 Phase 4 pantoloc 40 mg;somatostatin or terlipressin
11 The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed Completed NCT00534677 Phase 4 Terlipressin;Octreotide
12 A Trial of Nadolol Plus Isosorbide Mononitrate Versus Carvedilol for the Prevention of Variceal Rebleeding Completed NCT01103154 Phase 4 carvedilol;nadolol + ISMN
13 Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal Completed NCT01059396 Phase 4 propranolol;carvedilol;placebo
14 Short Course Terlipressin for Control of Acute Variceal Bleeding Completed NCT00369694 Phase 4 Terlipressin;Terlipressin & then Dummy
15 A Trial of Ligation Plus Nadolol Versus Nadolol Alone in the Prophylaxis of First Variceal Bleeding in Cirrhosis Completed NCT00921349 Phase 4 Nadolol
16 Optimized Treatment and Regression of HBV-induced Compensated Liver Cirrhosis Completed NCT01943617 Phase 4 Entecavir;Thymosin-α
17 Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy Completed NCT00570973 Phase 4
18 Comparison of 24-hours Versus 72-hours of Octreotide Infusion in Preventing Early Rebleed From Esophageal Varices Recruiting NCT03624517 Phase 4 Octreotide
19 EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment Recruiting NCT00966082 Phase 4
20 Endoscopic Band Ligation (EBL) Versus Endoscopic Band Ligation and Propranolol for the Prevention of Variceal Rebleeding Recruiting NCT00966121 Phase 4
21 Efficacity and Safety of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding Recruiting NCT03023189 Phase 4 Tranexamic acid;Placebo
22 Endoscopic Band Ligation (EBL) Versus Propranolol for Primary Prophylaxis of Variceal Bleeding Recruiting NCT00965900 Phase 4 Propranolol
23 Effect of Entecavir Treatment on Regression and Disease Outcome in HBV-induced Liver Fibrosis and Cirrhosis Patients Recruiting NCT02849132 Phase 4 Entecavir
24 Efficacy and Safety Study of Tenofovir Disoproxil Fumarate (TDF) in Chinese Chronic Hepatitis B (CHB) Subjects With Advanced Fibrosis & Compensated Cirrhosis Active, not recruiting NCT02224456 Phase 4 Tenofovir disoproxil fumarate
25 Beta-blockers for Oesophageal Varices Not yet recruiting NCT03776955 Phase 4 Carvedilol
26 Effect of Administration of Rifaximin on the Portal Pressure of Patients With Liver Cirrhosis and Esophageal Varices Unknown status NCT02508623 Phase 3 Rifaximin;Placebo
27 Rifaximin and Propranolol Combination Therapy Versus Propranolol Monotherapy in Cirrhotic Patients Unknown status NCT01897051 Phase 2, Phase 3 Rifaximin + propranolol;Propranolol + Placebo
28 Probiotics for Portal Hypertension Unknown status NCT01134692 Phase 3 Propranolol, Norfloxacin, VSL#3
29 ABMSC Infusion Through Hepatic Artery in Portal Hypertension Surgery for the Treatment of Liver Cirrhosis Unknown status NCT01560845 Phase 2, Phase 3
30 To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites Unknown status NCT02649335 Phase 3 Propranolol
31 TIPS for Variceal Rebleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis and CTPV Unknown status NCT02853526 Phase 3 Propranolol;Warfarin
32 Efficacy and Safety of Endoscopic Injection of Fibrin Sealant Versus Endoscopic Ligature for Bleeding Esophageal Varices Completed NCT00161915 Phase 3 Fibrin Sealant
33 Danish Carvedilol Study in Portal Hypertension Completed NCT00493480 Phase 3 carvedilol;propranolol
34 Prevention of Esophageal Varices by Beta-Adrenergic Blockers Completed NCT00006398 Phase 3 Timolol Maleate;Placebo
35 Comparison of Endoscopic Variceal Ligation (EVL) With Propranolol in Non Cirrhotic Portal Hypertension (NCPH) Completed NCT01000779 Phase 3 Propranolol
36 Simvastatin Effect on Portal Hypertension Completed NCT02134626 Phase 3 Simvastatin;Placebo pill
37 Self-expandable Esophageal Stent Versus Balloon Tamponade in Refractory Esophageal Variceal Bleeding. Completed NCT01242280 Phase 3
38 Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope Completed NCT01131962 Phase 3
39 Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleeding Completed NCT00331188 Phase 3 Sanvar® (vapreotide)
40 Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding Completed NCT01095185 Phase 3 Simvastatin;Placebo
41 Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis Completed NCT01654731 Phase 3 Bezafibrate;placebo
42 Hepatic Venous Pressure Gradient-guided Versus Standard Beta-blocker Therapy in Primary Prevention of Variceal Bleeding Recruiting NCT01618890 Phase 3
43 Scleroligation for Eradication of Gastroesophageal Varices. Recruiting NCT02646202 Phase 3
44 Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis Recruiting NCT02643212 Phase 3 Rivaroxaban;Placebo
45 Endoscopic Injection Sclerotherapy Versus N-butyl-2-cyanoacrylate Injection Active, not recruiting NCT03388125 Phase 3 Injection Sclerotherapy;N-butyl-2-cyanoacrylate
46 Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients Suspended NCT02271295 Phase 3 Enoxaparine
47 Beta Blockers Versus Variceal Band Ligation and Beta Blockers for Primary Prophylaxis of Variceal Bleeding Terminated NCT00409084 Phase 3
48 Banding Versus Propranolol for Primary Prophylaxis of Variceal Bleeding Terminated NCT00337740 Phase 3 propranolol
49 Enhancing Detection of Small Esophageal Varices by PillCam ESO Withdrawn NCT00911131 Phase 3
50 Carvedilol vs Band Ligation vs Combination Therapy for Primary Prophylaxis of Variceal Bleeding Withdrawn NCT02066649 Phase 3 Carvedilol

Search NIH Clinical Center for Esophageal Varix

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Genetic Tests for Esophageal Varix

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Genetic tests related to Esophageal Varix:

# Genetic test Affiliating Genes
1 Esophageal Varix 29
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Anatomical Context for Esophageal Varix

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MalaCards organs/tissues related to Esophageal Varix:

41
Liver, Spleen, Testes, Heart, Brain, Spinal Cord, Breast
Sources

Publications for Esophageal Varix

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Articles related to Esophageal Varix:

(show top 50) (show all 1073)
# Title Authors Year
1
Esophageal Varices in Adolescent and Young Adult Males with Acute Lymphocytic Leukemia. ( 30335538 )
2018
2
Direct reopening of the occluded hepatic veins of Budd-Chiari syndrome: verification of our operative method by the perioperative course of esophageal varices. ( 28828590 )
2018
3
Esophageal Ulcers in Primary Biliary Cholangitis: A Rare Cause of Hematemesis in the Setting of Portal Hypertension and Esophageal Varices. ( 30344813 )
2018
4
Insulin/high-density lipoprotein cholesterol ratio: A newly-discovered predictor of esophageal varices in patients with hepatitis C virus-related cirrhosis in the absence of diabetes mellitus. ( 30541737 )
2018
5
Non-invasive prediction of esophageal varices by stiffness and platelet in non-alcoholic fatty liver disease cirrhosis. ( 29802949 )
2018
6
Relationship between various hepatic function scores and the formation of esophageal varices in patients with HIV/hepatitis C virus co-infection due to contaminated blood products for hemophilia. ( 30358037 )
2018
7
Sclerotherapy of esophageal varices in hemophilia patients with liver cirrhosis - a prospective, controlled clinical study. ( 29513248 )
2018
8
Transient Elastography Identifies the Risk of Esophageal Varices and Bleeding in Patients With Hepatitis B Virus-Related Liver Cirrhosis. ( 30020268 )
2018
9
Predicting Esophageal Varices in Cirrhotic Hepatitis C Virus Patients Using Noninvasive Measurement of Insulin Resistance Variables. ( 30073932 )
2018
10
Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( 30344206 )
2018
11
Νon-invasive screening for esophageal varices in patients with liver cirrhosis. ( 29720856 )
2018
12
Concomitant Gastric Varices: Bleeding Risk Sign in Patients With Liver Cirrhosis and Esophageal Varices? ( 30142338 )
2018
13
Screening of Esophageal Varices by Noninvasive Means in Chronic Liver Disease. ( 29963456 )
2018
14
Spleen and liver stiffness for noninvasive assessment of portal hypertension in cirrhotic patients with large esophageal varices. ( 30132919 )
2018
15
Noninvasive Methods of Predicting Large Esophageal Varices in Children With Intrahepatic Portal Hypertension. ( 29176477 )
2018
16
Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. ( 30465524 )
2018
17
Small Esophageal Varices in Patients with Cirrhosis-Should We Treat Them? ( 30546995 )
2018
18
Role of dual red imaging to guide intravariceal sclerotherapy injection of esophageal varices (with videos). ( 28694009 )
2018
19
The noninvasive diagnosis of esophageal varices and its application in clinical practice. ( 28870440 )
2018
20
Gas6 as a predictor of esophageal varices in patients affected by hepatitis C virus related-chronic liver disease. ( 29243516 )
2018
21
Combination of albumin-bilirubin grade and platelets to predict a compensated patient with hepatocellular carcinoma who does not require endoscopic screening for esophageal varices. ( 29317268 )
2018
22
Gastric Varices Bleed at Lower Portosystemic Pressure Gradients than Esophageal Varices. ( 29352698 )
2018
23
Role of noninvasive markers to predict the presence of esophageal varices in cirrhosis: Pilot study. ( 29455439 )
2018
24
Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices. ( 29481430 )
2018
25
Transparent cap-assisted endoscopic sclerotherapy in esophageal varices: a randomized-controlled trial. ( 29505477 )
2018
26
Propranolol reduces systemic oxidative stress and endotoxemia in cirrhotic patients with esophageal varices. ( 29507470 )
2018
27
Persistence of gastric or esophageal varices on final angiography increases transjugular intrahepatic portosystemic shunt revision rate after polytetrafluoroethylene-covered stent shunt creation. ( 29675358 )
2018
28
Neurological symptoms and spinal cord embolism caused by endoscopic injection sclerotherapy for esophageal varices: A case report and literature review. ( 29718871 )
2018
29
Accuracy of liver stiffness, spleen stiffness, and LS-spleen diameter to platelet ratio score in detection of esophageal varices: Systemic review and meta-analysis. ( 29736946 )
2018
30
A Rare Case of Complete Esophageal Obstruction Following Esophageal Variceal Band Ligation (EVBL) for Esophageal Varices Performed by Esophagogastroduodenoscopy (EGD). ( 29739920 )
2018
31
Left gastric vein-based noninvasive test for esophageal varices: a same-day comparison of portal hemodynamic assessment with endoscopic appearance. ( 29795388 )
2018
32
Magnetic resonance elastography increases usefulness and safety of non-invasive screening for esophageal varices. ( 29869419 )
2018
33
Study of the influence of heme oxygenase 1 gene single nucleotide polymorphism (rs2071746) on esophageal varices among patients with cirrhosis. ( 29877949 )
2018
34
Crossing the minefield: EUS-guided transesophageal biliary rendezvous in the presence of esophageal varices and ascites. ( 29916478 )
2018
35
Esophageal varices are not predictive of patient prognosis after surgical resection of hepatocellular carcinoma. ( 29994873 )
2018
36
Meta-analysis of the accuracy of transient elastography in measuring liver stiffness to diagnose esophageal varices in cirrhosis. ( 29995773 )
2018
37
Screening for esophageal varices in patients with hepatocellular carcinoma. ( 30012408 )
2018
38
Gall bladder wall thickening as non-invasive screening parameter for esophageal varices - a comparative endoscopic - sonographic study. ( 30071840 )
2018
39
Screening of esophageal varices in children using esophageal capsule endoscopy: a multicenter prospective study. ( 30184608 )
2018
40
Presumptive non-cirrhotic bleeding esophageal varices in a dog. ( 30216560 )
2018
41
Ruling out esophageal varices in NAFLD cirrhosis: Can we do without endoscopy? ( 30227915 )
2018
42
Non-invasive response prediction in prophylactic carvedilol therapy for cirrhotic patients with esophageal varices. ( 30389550 )
2018
43
The imbalance of peripheral interleukin-18 and transforming growth factor-β1 levels in patients with cirrhosis and esophageal varices. ( 30392846 )
2018
44
Esophageal Varix in an Adult Fontan Survivor. ( 29021468 )
2017
45
Successful endoscopic submucosal dissection for superficial esophageal cancer on solitary esophageal varix. ( 28576395 )
2017
46
Narrow-band imaging can increase the visibility of fibrin caps after bleeding of esophageal varices: a case with extensive esophageal candidiasis. ( 28500570 )
2017
47
Noninvasive assessment of portal hypertension and detection of esophageal varices in cirrhosis: state-of-the-art. ( 28079668 )
2017
48
Role of Serum Soluble CD163 in the Diagnosis, Risk of Bleeding, and Prognosis of Gastro-Esophageal Varices in Cirrhotic Patients. ( 28282272 )
2017
49
Pulmonary vein stenosis with collateralization via esophageal varices: Long-term follow-up after successful treatment with drug-eluting stent. ( 28924998 )
2017
50
Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices. ( 28883247 )
2017
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Variations for Esophageal Varix

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Expression for Esophageal Varix

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Search GEO for disease gene expression data for Esophageal Varix.
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Pathways for Esophageal Varix

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Pathways related to Esophageal Varix according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
FOXA2 and FOXA3 transcription factor networks 1
10.44 AFP ALB F2
Sources

GO Terms for Esophageal Varix

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Cellular components related to Esophageal Varix according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.63 AFP ALB ATP4A F2 SERPINC1 SST
2 blood microparticle GO:0072562 9.13 ALB F2 SERPINC1
3 endoplasmic reticulum lumen GO:0005788 8.92 AFP ALB F2 SERPINC1

Biological processes related to Esophageal Varix according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium ion transport GO:0006814 9.54 ATP12A ATP4A SLC4A4
2 potassium ion import across plasma membrane GO:1990573 9.48 ATP12A ATP4A
3 potassium ion import GO:0010107 9.46 ATP12A ATP4A
4 ATP hydrolysis coupled proton transport GO:0015991 9.43 ATP12A ATP4A
5 cellular sodium ion homeostasis GO:0006883 9.4 ATP12A ATP4A
6 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.32 ATP12A ATP4A
7 cellular potassium ion homeostasis GO:0030007 9.26 ATP12A ATP4A
8 regulation of blood coagulation GO:0030193 9.16 F2 SERPINC1
9 sodium ion export across plasma membrane GO:0036376 8.96 ATP12A ATP4A
10 cellular protein metabolic process GO:0044267 8.92 AFP ALB F2 SERPINC1

Molecular functions related to Esophageal Varix according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A
Sources

Sources for Esophageal Varix

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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