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MCID: ESP002
MIFTS: 50

Esophageal Varix

Categories: Cardiovascular diseases, Gastrointestinal diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Esophageal Varix

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MalaCards integrated aliases for Esophageal Varix:

Name: Esophageal Varix 12 30 15
Esophageal Varices 12 77 54 56 15 17
Bleeding Esophageal Varices 12 56 74
Esophageal Varices in Disease Classified Elsewhere, with Bleeding 12
Esophageal Varices with Bleeding in Disease Ec 12
Esophageal Varices Without Mention of Bleeding 12
Esophageal Varices Without Bleeding 12
Esophageal Varices with Bleeding 12
Bleeding Oesophageal Varices 12

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Gastrointestinal diseases Cardiovascular diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:112
ICD9CM 36 456.0 456.2 456.20
NCIt 51 C78282
SNOMED-CT 69 17709002
ICD10 34 I85.01
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Summaries for Esophageal Varix

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MalaCards based summary : Esophageal Varix, also known as esophageal varices, is related to portal hypertension and alcoholic liver cirrhosis. An important gene associated with Esophageal Varix is SST (Somatostatin), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. The drugs Propranolol and Nitric Oxide have been mentioned in the context of this disorder. Affiliated tissues include liver, spleen and heart, and related phenotypes are Strongly decreased CFP-tsO45G cell surface transport and digestive/alimentary

Wikipedia : 77 Esophageal varices (sometimes spelled esophageal varix, or oesophageal varices) are extremely dilated... more...

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Related Diseases for Esophageal Varix

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Diseases related to Esophageal Varix via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 245)
# Related Disease Score Top Affiliating Genes
1 portal hypertension 30.7 ALB DGUOK F2 GPT SST
2 alcoholic liver cirrhosis 30.4 AFP ALB F2
3 hypersplenism 30.4 ALB F2
4 bilirubin metabolic disorder 30.3 ALB F2 GPT
5 hepatic coma 30.2 ALB F2 GPT
6 cholangitis 30.2 ALB F2 GPT
7 portal vein thrombosis 30.2 AFP F2
8 hepatic encephalopathy 30.2 ALB F2 GPT
9 alcoholic hepatitis 30.2 ALB F2 GPT
10 hepatitis 30.2 AFP F2 GPT
11 hepatorenal syndrome 30.2 ALB F2
12 infantile liver failure syndrome 1 30.0 ALB F2 GPT
13 obstructive jaundice 30.0 ALB F2 GPT
14 esophageal candidiasis 30.0 ATP12A ATP4A
15 duodenitis 30.0 ATP12A ATP4A
16 liver cirrhosis 30.0 AFP ALB F2 GPT SST
17 peptic esophagitis 30.0 ATP12A ATP4A
18 hepatitis b 29.9 AFP ALB F2 GPT
19 microinvasive gastric cancer 29.9 ATP12A ATP4A
20 liver disease 29.8 AFP ALB F2 GPT
21 nodular regenerative hyperplasia 11.8
22 cerebroretinal microangiopathy with calcifications and cysts 2 11.3
23 varicose veins 11.0
24 hepatitis c 10.5
25 biliary atresia 10.4
26 hepatitis c virus 10.4
27 antipyrine metabolism 10.4 ALB F2
28 non-a-e hepatitis 10.4 ALB F2
29 epstein-barr virus hepatitis 10.4 ALB F2
30 yellow nail syndrome 10.4 ALB SST
31 fournier gangrene 10.4 ALB F2
32 abdominal tuberculosis 10.4 ALB F2
33 chylothorax, congenital 10.3 ALB SST
34 hepatoportal sclerosis 10.3 F2 GPT
35 primary biliary cholangitis 10.3
36 splenic disease 10.3 ALB F2
37 endometrial small cell carcinoma 10.3 AFP F2
38 ascending cholangitis 10.3 ALB F2
39 biliary cirrhosis, primary, 1 10.3
40 primary biliary cirrhosis 10.3
41 pancreatoblastoma 10.3 AFP SST
42 hepatitis d 10.3 F2 GPT
43 hepatoid adenocarcinoma 10.3 AFP ALB
44 nonalcoholic steatohepatitis 10.3 F2 GPT
45 compartment syndrome 10.3 ALB F2
46 drug allergy 10.2 ALB ATP12A
47 opisthorchiasis 10.2 AFP GPT
48 fascioliasis 10.2 ALB GPT
49 endodermal sinus tumor 10.2 AFP ALB
50 diabetes mellitus, noninsulin-dependent 10.2

Comorbidity relations with Esophageal Varix via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Cystitis
Alcoholic Liver Cirrhosis Deficiency Anemia
Esophageal Disease Esophagitis
Heart Disease Hepatic Encephalopathy
Portal Hypertension

Graphical network of the top 20 diseases related to Esophageal Varix:



Diseases related to Esophageal Varix
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Symptoms & Phenotypes for Esophageal Varix

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GenomeRNAi Phenotypes related to Esophageal Varix according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Strongly decreased CFP-tsO45G cell surface transport GR00360-A-2 8.92 DGUOK GPT JMJD6 SST

MGI Mouse Phenotypes related to Esophageal Varix:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.43 ALB ATP12A ATP4A F2 JMJD6 SST
2 homeostasis/metabolism MP:0005376 9.28 AFP ALB ATP12A ATP4A EOGT F2
Sources

Drugs & Therapeutics for Esophageal Varix

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Drugs for Esophageal Varix (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 135)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propranolol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 525-66-6 4946
2
Nitric Oxide Approved Phase 4,Phase 3 10102-43-9 145068
3
AT-101 Approved, Investigational Phase 4 90141-22-3, 652-67-5 12597
4
Nadolol Approved Phase 4,Phase 3 42200-33-9 39147
5
Isosorbide Dinitrate Approved, Investigational Phase 4 87-33-2 6883
6
Prazosin Approved Phase 4 19216-56-9 4893
7
Simvastatin Approved Phase 4,Phase 3,Not Applicable 79902-63-9 54454
8
Carvedilol Approved, Investigational Phase 4,Phase 3,Not Applicable 72956-09-3 2585
9
Somatostatin Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 38916-34-6, 51110-01-1 53481605
10
Octreotide Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 83150-76-9 6400441 383414
11
Terlipressin Approved, Investigational Phase 4,Not Applicable 14636-12-5 72081
12
Ethanolamine oleate Approved Phase 4,Phase 3 2272-11-9
13 Ethiodized oil Approved, Investigational Phase 4,Not Applicable 8008-53-5
14
Entecavir Approved, Investigational Phase 4,Not Applicable 142217-69-4 153941
15
Tranexamic Acid Approved Phase 4 1197-18-8 5526
16
Telbivudine Approved, Investigational Phase 4,Not Applicable 3424-98-4 159269
17
Tenofovir Approved, Experimental, Investigational Phase 4,Not Applicable 147127-20-6 464205
18
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 68-26-8, 22737-96-8, 11103-57-4 9904001 445354
19
Calcium Approved, Nutraceutical Phase 4,Phase 3,Not Applicable 7440-70-2 271
20 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Not Applicable
21 Vasodilator Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
22 Adrenergic Agents Phase 4,Phase 2,Phase 3,Not Applicable
23 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 3,Not Applicable
24 Antihypertensive Agents Phase 4,Phase 2,Phase 3,Not Applicable
25 Adrenergic beta-Antagonists Phase 4,Phase 2,Phase 3,Not Applicable
26 Adrenergic Antagonists Phase 4,Phase 2,Phase 3,Not Applicable
27 Natriuretic Agents Phase 4,Not Applicable
28 Peripheral Nervous System Agents Phase 4,Phase 3,Not Applicable
29 Adrenergic alpha-1 Receptor Antagonists Phase 4,Phase 3,Not Applicable
30 Adrenergic alpha-Antagonists Phase 4,Phase 3,Not Applicable
31 Sympatholytics Phase 4
32 isosorbide-5-mononitrate Phase 4
33 Nitric Oxide Donors Phase 4
34 diuretics Phase 4
35 Autonomic Agents Phase 4,Not Applicable
36 Lipid Regulating Agents Phase 4,Phase 3,Not Applicable
37 Hypolipidemic Agents Phase 4,Phase 3,Not Applicable
38 Anticholesteremic Agents Phase 4,Phase 3,Not Applicable
39 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4,Phase 3,Not Applicable
40 Antimetabolites Phase 4,Phase 3,Not Applicable
41 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
42 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
43 Hormone Antagonists Phase 4,Not Applicable
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Not Applicable
45 Hormones Phase 4,Phase 3,Not Applicable
46 Anti-Infective Agents Phase 4,Phase 3,Phase 2
47 Retinol palmitate Phase 4
48 retinol Phase 4
49 Antineoplastic Agents, Hormonal Phase 4,Phase 1,Phase 2
50 Vasoconstrictor Agents Phase 4,Not Applicable

Interventional clinical trials:

(show top 50) (show all 142)
# Name Status NCT ID Phase Drugs
1 Preventing Recurrent Bleeding After Eradication of Esophageal Varices Unknown status NCT02740166 Phase 4 propranolol
2 Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices Unknown status NCT01970748 Phase 4 Propranolol
3 Endoscopic Treatment Alone Versus Combined Propranolol and Endoscopic Treatment of Acute Variceal Hemorrhage in Patients With Hepatocellular Carcinoma Unknown status NCT01451658 Phase 4 propranolol
4 Treatment for Prevention of Variceal Rebleeding Guided by the Hemodynamic Response Unknown status NCT00563602 Phase 4
5 Hemodynamic Effect of Simvastatin With Beta Blockers in Clinical Portal Hypertension Unknown status NCT01282385 Phase 4 Simvastatin;placebo
6 PROPRANOLOL PLUS LIGATION REDUCES RECURRENCE OF ESOPHAGEAL VARICES? Completed NCT01893541 Phase 4 PROPRANOLOL
7 Time Interval for Endoscopic Variceal Ligation Completed NCT01291277 Phase 4
8 Hemodynamic Effects of Terlipressin and High Dose Octreotide Completed NCT02119884 Phase 4 Terlipressin;Octreotide
9 A Randomized Controlled Trial Comparing Band Ligation and Cyanoacrylate Injection for Esophageal Varices Completed NCT00799851 Phase 4 cyanoacrylate injection
10 EVL (Endoscopic Variceal Ligation) Plus Vasoconstrictor vs.Ligation Plus PPI( Proton Pump Inhibitor) in the Control of Acute Esophageal Variceal Bleeding Completed NCT01112852 Phase 4 pantoloc 40 mg;somatostatin or terlipressin
11 The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed Completed NCT00534677 Phase 4 Terlipressin;Octreotide
12 A Trial of Nadolol Plus Isosorbide Mononitrate Versus Carvedilol for the Prevention of Variceal Rebleeding Completed NCT01103154 Phase 4 carvedilol;nadolol + ISMN
13 Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal Completed NCT01059396 Phase 4 propranolol;carvedilol;placebo
14 Short Course Terlipressin for Control of Acute Variceal Bleeding Completed NCT00369694 Phase 4 Terlipressin;Terlipressin & then Dummy
15 A Trial of Ligation Plus Nadolol Versus Nadolol Alone in the Prophylaxis of First Variceal Bleeding in Cirrhosis Completed NCT00921349 Phase 4 Nadolol
16 Optimized Treatment and Regression of HBV-induced Compensated Liver Cirrhosis Completed NCT01943617 Phase 4 Entecavir;Thymosin-α
17 Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy Completed NCT00570973 Phase 4
18 Comparison of 24-hours Versus 72-hours of Octreotide Infusion in Preventing Early Rebleed From Esophageal Varices Recruiting NCT03624517 Phase 4 Octreotide
19 EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment Recruiting NCT00966082 Phase 4
20 Endoscopic Band Ligation (EBL) Versus Endoscopic Band Ligation and Propranolol for the Prevention of Variceal Rebleeding Recruiting NCT00966121 Phase 4
21 Efficacity and Safety of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding Recruiting NCT03023189 Phase 4 Tranexamic acid;Placebo
22 Endoscopic Band Ligation (EBL) Versus Propranolol for Primary Prophylaxis of Variceal Bleeding Recruiting NCT00965900 Phase 4 Propranolol
23 Effect of Entecavir Treatment on Regression and Disease Outcome in HBV-induced Liver Fibrosis and Cirrhosis Patients Recruiting NCT02849132 Phase 4 Entecavir
24 Efficacy and Safety Study of Tenofovir Disoproxil Fumarate (TDF) in Chinese Chronic Hepatitis B (CHB) Subjects With Advanced Fibrosis & Compensated Cirrhosis Active, not recruiting NCT02224456 Phase 4 Tenofovir disoproxil fumarate
25 Beta-blockers for Oesophageal Varices Not yet recruiting NCT03776955 Phase 4 Carvedilol
26 Effect of Administration of Rifaximin on the Portal Pressure of Patients With Liver Cirrhosis and Esophageal Varices Unknown status NCT02508623 Phase 3 Rifaximin;Placebo
27 Rifaximin and Propranolol Combination Therapy Versus Propranolol Monotherapy in Cirrhotic Patients Unknown status NCT01897051 Phase 2, Phase 3 Rifaximin + propranolol;Propranolol + Placebo
28 Probiotics for Portal Hypertension Unknown status NCT01134692 Phase 3 Propranolol, Norfloxacin, VSL#3
29 ABMSC Infusion Through Hepatic Artery in Portal Hypertension Surgery for the Treatment of Liver Cirrhosis Unknown status NCT01560845 Phase 2, Phase 3
30 To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites Unknown status NCT02649335 Phase 3 Propranolol
31 TIPS for Variceal Rebleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis and CTPV Unknown status NCT02853526 Phase 3 Propranolol;Warfarin
32 Efficacy and Safety of Endoscopic Injection of Fibrin Sealant Versus Endoscopic Ligature for Bleeding Esophageal Varices Completed NCT00161915 Phase 3 Fibrin Sealant
33 Danish Carvedilol Study in Portal Hypertension Completed NCT00493480 Phase 3 carvedilol;propranolol
34 Prevention of Esophageal Varices by Beta-Adrenergic Blockers Completed NCT00006398 Phase 3 Timolol Maleate;Placebo
35 Comparison of Endoscopic Variceal Ligation (EVL) With Propranolol in Non Cirrhotic Portal Hypertension (NCPH) Completed NCT01000779 Phase 3 Propranolol
36 Simvastatin Effect on Portal Hypertension Completed NCT02134626 Phase 3 Simvastatin;Placebo pill
37 Self-expandable Esophageal Stent Versus Balloon Tamponade in Refractory Esophageal Variceal Bleeding. Completed NCT01242280 Phase 3
38 Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope Completed NCT01131962 Phase 3
39 Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleeding Completed NCT00331188 Phase 3 Sanvar® (vapreotide)
40 Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding Completed NCT01095185 Phase 3 Simvastatin;Placebo
41 Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis Completed NCT01654731 Phase 3 Bezafibrate;placebo
42 Hepatic Venous Pressure Gradient-guided Versus Standard Beta-blocker Therapy in Primary Prevention of Variceal Bleeding Recruiting NCT01618890 Phase 3
43 Scleroligation for Eradication of Gastroesophageal Varices. Recruiting NCT02646202 Phase 3
44 Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis Recruiting NCT02643212 Phase 3 Rivaroxaban;Placebo
45 Endoscopic Injection Sclerotherapy Versus N-butyl-2-cyanoacrylate Injection Active, not recruiting NCT03388125 Phase 3 Injection Sclerotherapy;N-butyl-2-cyanoacrylate
46 Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients Suspended NCT02271295 Phase 3 Enoxaparine
47 Beta Blockers Versus Variceal Band Ligation and Beta Blockers for Primary Prophylaxis of Variceal Bleeding Terminated NCT00409084 Phase 3
48 Banding Versus Propranolol for Primary Prophylaxis of Variceal Bleeding Terminated NCT00337740 Phase 3 propranolol
49 Enhancing Detection of Small Esophageal Varices by PillCam ESO Withdrawn NCT00911131 Phase 3
50 Carvedilol vs Band Ligation vs Combination Therapy for Primary Prophylaxis of Variceal Bleeding Withdrawn NCT02066649 Phase 3 Carvedilol

Search NIH Clinical Center for Esophageal Varix

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Genetic Tests for Esophageal Varix

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Genetic tests related to Esophageal Varix:

# Genetic test Affiliating Genes
1 Esophageal Varix 30
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Anatomical Context for Esophageal Varix

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MalaCards organs/tissues related to Esophageal Varix:

42
Liver, Spleen, Heart, Testes, Brain, Colon, Spinal Cord
Sources

Publications for Esophageal Varix

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Articles related to Esophageal Varix:

(show top 50) (show all 1867)
# Title Authors Year
1
Liaoning Score for Prediction of Esophageal Varices in Cirrhotic Patients Who Had Never Undergone Endoscopy: A Multicenter Cross-Sectional Study in Liaoning Province, China. ( 31093864 )
2019
2
An unusual cause of esophageal varices. ( 31063778 )
2019
3
Prediction of esophageal varices by liver and spleen MR elastography. ( 31041563 )
2019
4
Diagnostic Accuracy of Multidetector Computed Tomography in Detection of Esophageal Varices. ( 30931201 )
2019
5
Changes in Liver and Spleen Stiffness by Virtual Touch Quantification Technique after Balloon-Occluded Retrograde Transvenous Obliteration of Gastric Varices and Exacerbation of Esophageal Varices: A Preliminary Study. ( 30909311 )
2019
6
Blood platelet function abnormalities in cirrhotic patients with esophageal varices in relation to the variceal bleeding history. ( 30907172 )
2019
7
Safety of Transesophageal Echocardiography in Patients with Esophageal Varices. ( 30846321 )
2019
8
Utility of measuring para-esophageal varices using computed tomography to select endoscopic treatment for patients with esophageal varices. ( 30821863 )
2019
9
Endoscopic injection sclerotherapy for pediatric bleeding esophageal varices complicated by gastric vein, main portal vein, splenic mesenteric junction, and splenic vein occlusion: a case report. ( 30819091 )
2019
10
A study on spleen transient elastography in predicting the degree of esophageal varices and bleeding. ( 30817578 )
2019
11
The Changing Scenario of Screening and Surveillance of Esophageal Varices. ( 30776346 )
2019
12
Validation of Baveno VI Criteria for Screening and Surveillance of Esophageal Varices in Patients with Compensated Cirrhosis and a Sustained Response to Antiviral Therapy. ( 30768988 )
2019
13
Endoscopic injection sclerotherapy versus N-Butyl-2 Cyanoacrylate injection in the management of actively bleeding esophageal varices: a randomized controlled trial. ( 30717684 )
2019
14
Machine Learning-based Development and Validation of a Scoring System for Screening High-Risk Esophageal Varices. ( 30708109 )
2019
15
Bleeding Risk of Transesophageal Echocardiography in Patients With Esophageal Varices. ( 30665728 )
2019
16
Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. ( 30465524 )
2019
17
Non-invasive response prediction in prophylactic carvedilol therapy for cirrhotic patients with esophageal varices. ( 30389550 )
2019
18
The Right Liver Lobe Size/Albumin Concentration Ratio in Identifying Esophageal Varices among Patients with Liver Cirrhosis. ( 31049180 )
2019
19
Acute mesenteric vein thrombosis after endoscopic injection sclerotherapy for esophageal varices in a patient with liver cirrhosis. ( 31080203 )
2019
20
Prediction of Aspartate Aminotransferase to Platelet Ratio Index with Size of Esophageal Varices in Liver Cirrhosis. ( 31110374 )
2019
21
The treatment of achalasia patients with esophageal varices: an international study. ( 31065374 )
2019
22
Screening of esophageal varices in children using esophageal capsule endoscopy: a multicenter prospective study. ( 30184608 )
2019
23
Elastography-based screening for esophageal varices in patients with advanced chronic liver disease. ( 30686900 )
2019
24
Evaluation of liver stiffness by 2D-SWE in combination with non-invasive parameters as predictors for esophageal varices in patients with advanced chronic liver disease. ( 30879344 )
2019
25
Long-term outcome of endoscopic variceal band ligation of esophageal varices in patients with chronic liver disease. ( 30868452 )
2019
26
Relationship between various hepatic function scores and the formation of esophageal varices in patients with HIV/hepatitis C virus co-infection due to contaminated blood products for hemophilia. ( 30358037 )
2019
27
Esophageal Varices in Adolescent and Young Adult Males with Acute Lymphocytic Leukemia. ( 30335538 )
2019
28
Ruling out esophageal varices in NAFLD cirrhosis: Can we do without endoscopy? ( 30227915 )
2018
29
Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices. ( 29481430 )
2018
30
Role of noninvasive markers to predict the presence of esophageal varices in cirrhosis: Pilot study. ( 29455439 )
2018
31
Gastric Varices Bleed at Lower Portosystemic Pressure Gradients than Esophageal Varices. ( 29352698 )
2018
32
Combination of albumin-bilirubin grade and platelets to predict a compensated patient with hepatocellular carcinoma who does not require endoscopic screening for esophageal varices. ( 29317268 )
2018
33
The noninvasive diagnosis of esophageal varices and its application in clinical practice. ( 28870440 )
2018
34
Transparent cap-assisted endoscopic sclerotherapy in esophageal varices: a randomized-controlled trial. ( 29505477 )
2018
35
Propranolol reduces systemic oxidative stress and endotoxemia in cirrhotic patients with esophageal varices. ( 29507470 )
2018
36
Insulin/high-density lipoprotein cholesterol ratio: A newly-discovered predictor of esophageal varices in patients with hepatitis C virus-related cirrhosis in the absence of diabetes mellitus. ( 30541737 )
2018
37
Esophageal Ulcers in Primary Biliary Cholangitis: A Rare Cause of Hematemesis in the Setting of Portal Hypertension and Esophageal Varices. ( 30344813 )
2018
38
Direct reopening of the occluded hepatic veins of Budd-Chiari syndrome: verification of our operative method by the perioperative course of esophageal varices. ( 28828590 )
2018
39
Role of dual red imaging to guide intravariceal sclerotherapy injection of esophageal varices (with videos). ( 28694009 )
2018
40
Prediction of the presence of esophageal varices using spleen stiffness measurement by transient elastography in cirrhotic patients. ( 30645918 )
2018
41
Downhill esophageal varices: a therapeutic dilemma. ( 30603651 )
2018
42
Small Esophageal Varices in Patients with Cirrhosis-Should We Treat Them? ( 30546995 )
2018
43
The imbalance of peripheral interleukin-18 and transforming growth factor-β1 levels in patients with cirrhosis and esophageal varices. ( 30392846 )
2018
44
Pulmonary vein stenosis with collateralization via esophageal varices: Long-term follow-up after successful treatment with drug-eluting stent. ( 28924998 )
2018
45
Non-invasive prediction of esophageal varices by stiffness and platelet in non-alcoholic fatty liver disease cirrhosis. ( 29802949 )
2018
46
Predicting Esophageal Varices in Cirrhotic Hepatitis C Virus Patients Using Noninvasive Measurement of Insulin Resistance Variables. ( 30073932 )
2018
47
Concomitant Gastric Varices: Bleeding Risk Sign in Patients With Liver Cirrhosis and Esophageal Varices? ( 30142338 )
2018
48
Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( 30344206 )
2018
49
Νon-invasive screening for esophageal varices in patients with liver cirrhosis. ( 29720856 )
2018
50
Spleen and liver stiffness for noninvasive assessment of portal hypertension in cirrhotic patients with large esophageal varices. ( 30132919 )
2018
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Variations for Esophageal Varix

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Expression for Esophageal Varix

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Search GEO for disease gene expression data for Esophageal Varix.
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Pathways for Esophageal Varix

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Pathways related to Esophageal Varix according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
FOXA2 and FOXA3 transcription factor networks 1
10.44 AFP ALB F2
Sources

GO Terms for Esophageal Varix

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Cellular components related to Esophageal Varix according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 AFP ALB ATP4A F2 GPT SST
2 endoplasmic reticulum lumen GO:0005788 8.92 AFP ALB EOGT F2

Biological processes related to Esophageal Varix according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.63 F2 JMJD6 SST
2 cellular protein metabolic process GO:0044267 9.58 AFP ALB F2
3 potassium ion import across plasma membrane GO:1990573 9.43 ATP12A ATP4A
4 ATP hydrolysis coupled proton transport GO:0015991 9.37 ATP12A ATP4A
5 apoptotic cell clearance GO:0043277 9.32 JMJD6 LRP1
6 cellular sodium ion homeostasis GO:0006883 9.26 ATP12A ATP4A
7 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP12A ATP4A
8 cellular potassium ion homeostasis GO:0030007 8.96 ATP12A ATP4A
9 sodium ion export across plasma membrane GO:0036376 8.62 ATP12A ATP4A

Molecular functions related to Esophageal Varix according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A
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Sources for Esophageal Varix

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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