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MCID: ESP002
MIFTS: 48

Esophageal Varix

Categories: Rare diseases, Gastrointestinal diseases, Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Esophageal Varix

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MalaCards integrated aliases for Esophageal Varix:

Name: Esophageal Varix 12 29 15
Esophageal Varices 12 76 53 55
Bleeding Esophageal Varices 12 55 73
Esophageal Varices in Disease Classified Elsewhere, with Bleeding 12
Esophageal Varices with Bleeding in Disease Ec 12
Esophageal Varices Without Mention of Bleeding 12
Esophageal Varices Without Bleeding 12
Esophageal Varices with Bleeding 12
Bleeding Oesophageal Varices 12

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Gastrointestinal diseases Cardiovascular diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:112
ICD10 33 I85.01
ICD9CM 35 456.0 456.2 456.20
NCIt 50 C78282
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Summaries for Esophageal Varix

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MalaCards based summary : Esophageal Varix, also known as esophageal varices, is related to alcoholic liver cirrhosis and liver disease. An important gene associated with Esophageal Varix is SST (Somatostatin), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. The drugs Propranolol and AT-101 have been mentioned in the context of this disorder. Affiliated tissues include liver, spleen and testes, and related phenotypes are digestive/alimentary and homeostasis/metabolism

Wikipedia : 76 Esophageal varices (sometimes spelled oesophageal varices) are extremely dilated sub-mucosal veins in... more...

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Related Diseases for Esophageal Varix

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Diseases related to Esophageal Varix via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 160)
# Related Disease Score Top Affiliating Genes
1 alcoholic liver cirrhosis 30.5 AFP ALB F2
2 liver disease 30.0 AFP ALB F2
3 liver cirrhosis 28.6 AFP ALB F2 SERPINC1 SST
4 budd-chiari syndrome 11.4
5 nodular regenerative hyperplasia 11.4
6 cerebroretinal microangiopathy with calcifications and cysts 2 11.1
7 antipyrine metabolism 10.8 ALB F2
8 non-a-e hepatitis 10.8 ALB F2
9 abdominal tuberculosis 10.8 ALB F2
10 kwashiorkor 10.8 ALB F2
11 yellow nail syndrome 10.8 ALB SST
12 hepatic tuberculosis 10.8 ALB F2
13 chylothorax, congenital 10.8 ALB SST
14 hepatic coma 10.8 ALB F2
15 endometrial small cell carcinoma 10.7 AFP F2
16 splenic disease 10.7 ALB F2
17 pancreatoblastoma 10.7 AFP SST
18 vitamin k deficiency hemorrhagic disease 10.7 AFP F2
19 hepatoid adenocarcinoma 10.7 AFP ALB
20 ascending cholangitis 10.7 ALB F2
21 fungal esophagitis 10.6 ATP12A ATP4A
22 compartment syndrome 10.6 ALB F2
23 bladder calculus 10.6 ATP12A ATP4A
24 neonatal candidiasis 10.6 ATP12A ATP4A
25 photoallergic dermatitis 10.6 ATP12A ATP4A
26 squamous papillomatosis 10.6 ATP12A ATP4A
27 acute laryngitis 10.6 ATP12A ATP4A
28 gastroduodenal crohn's disease 10.6 ATP12A ATP4A
29 toxic megacolon 10.6 ATP12A ATP4A
30 aspiration pneumonitis 10.6 ATP12A ATP4A
31 postsurgical hypothyroidism 10.6 ATP12A ATP4A
32 esophageal candidiasis 10.6 ATP12A ATP4A
33 duodenitis 10.6 ATP12A ATP4A
34 rumination disorder 10.6 ATP12A ATP4A
35 bile reflux 10.6 ATP12A ATP4A
36 choledocholithiasis 10.6 ALB F2
37 granulomatous gastritis 10.6 ATP12A ATP4A
38 laryngeal disease 10.6 ATP12A ATP4A
39 peptic esophagitis 10.6 ATP12A ATP4A
40 endodermal sinus tumor 10.6 AFP ALB
41 duodenal disease 10.6 ATP12A ATP4A
42 dyskinesia of esophagus 10.6 ATP12A ATP4A
43 hernia, hiatus 10.6 ATP12A ATP4A
44 congenital disorder of deglycosylation 10.6 ATP12A ATP4A
45 anismus 10.6 ATP12A ATP4A
46 hepatorenal syndrome 10.6 ALB F2
47 esophageal atresia/tracheoesophageal fistula 10.6 ATP12A ATP4A
48 laryngitis 10.6 ATP12A ATP4A
49 esophagitis 10.6
50 laryngeal tuberculosis 10.6 ATP12A ATP4A

Comorbidity relations with Esophageal Varix via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Cystitis
Alcoholic Liver Cirrhosis Deficiency Anemia
Esophageal Disease Esophagitis
Heart Disease Hepatic Encephalopathy
Portal Hypertension

Graphical network of the top 20 diseases related to Esophageal Varix:



Diseases related to Esophageal Varix
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Symptoms & Phenotypes for Esophageal Varix

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MGI Mouse Phenotypes related to Esophageal Varix:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.7 F2 JMJD6 SLC4A4 SST ALB ATP12A
2 homeostasis/metabolism MP:0005376 9.65 JMJD6 SERPINC1 SLC4A4 SST AFP ALB
3 renal/urinary system MP:0005367 9.02 JMJD6 SERPINC1 SLC4A4 ALB ATP12A
Sources

Drugs & Therapeutics for Esophageal Varix

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Drugs for Esophageal Varix (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 133)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propranolol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 525-66-6 4946
2
AT-101 Approved, Investigational Phase 4 90141-22-3, 652-67-5 12597
3
Isosorbide Dinitrate Approved, Investigational Phase 4 87-33-2 6883
4
Nadolol Approved Phase 4,Phase 3 42200-33-9 39147
5
Nitric Oxide Approved Phase 4,Phase 3 10102-43-9 145068 160954
6
Prazosin Approved Phase 4 19216-56-9 4893
7
Carvedilol Approved, Investigational Phase 4,Phase 3,Not Applicable 72956-09-3 2585
8
Simvastatin Approved Phase 4,Phase 3,Not Applicable 79902-63-9 54454
9
Somatostatin Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 38916-34-6, 51110-01-1 53481605
10
Octreotide Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 83150-76-9 383414 6400441
11
Terlipressin Approved, Investigational Phase 4,Not Applicable 14636-12-5 72081
12
ethanolamine oleate Approved Phase 4,Phase 3 2272-11-9
13
Ethiodized oil Approved, Investigational Phase 4,Not Applicable 8008-53-5
14
Entecavir Approved, Investigational Phase 4 142217-69-4 153941
15
Menthol Approved Phase 4,Phase 3 2216-51-5 16666
16
Tranexamic Acid Approved Phase 4 1197-18-8 5526
17
Telbivudine Approved, Investigational Phase 4 3424-98-4 159269
18
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 11103-57-4, 68-26-8 445354
19 Adrenergic Agents Phase 4,Phase 2,Phase 3,Not Applicable
20 Adrenergic Antagonists Phase 4,Phase 2,Phase 3,Not Applicable
21 Adrenergic beta-Antagonists Phase 4,Phase 2,Phase 3,Not Applicable
22 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 3,Not Applicable
23 Antihypertensive Agents Phase 4,Phase 2,Phase 3,Not Applicable
24 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Not Applicable
25 Vasodilator Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
26 Adrenergic alpha-1 Receptor Antagonists Phase 4,Phase 3,Not Applicable
27 Adrenergic alpha-Antagonists Phase 4,Phase 3,Not Applicable
28 Autonomic Agents Phase 4,Not Applicable
29 diuretics Phase 4
30 isosorbide-5-mononitrate Phase 4
31 Natriuretic Agents Phase 4,Not Applicable
32 Nitric Oxide Donors Phase 4
33 Peripheral Nervous System Agents Phase 4,Phase 3,Not Applicable
34 Sympatholytics Phase 4
35 Anticholesteremic Agents Phase 4,Phase 3,Not Applicable
36 Antimetabolites Phase 4,Phase 3,Not Applicable
37 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4,Phase 3,Not Applicable
38 Hypolipidemic Agents Phase 4,Phase 3,Not Applicable
39 Lipid Regulating Agents Phase 4,Phase 3,Not Applicable
40 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Hormone Antagonists Phase 4,Not Applicable
43 Hormones Phase 4,Not Applicable
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Not Applicable
45 Anti-Infective Agents Phase 4,Phase 3,Phase 2
46 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
47 Retinol palmitate Phase 4
48 Antineoplastic Agents, Hormonal Phase 4,Phase 1,Phase 2
49 Coagulants Phase 4,Phase 3,Not Applicable
50 Hemostatics Phase 4,Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 129)
# Name Status NCT ID Phase Drugs
1 Preventing Recurrent Bleeding After Eradication of Esophageal Varices Unknown status NCT02740166 Phase 4 propranolol
2 Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices Unknown status NCT01970748 Phase 4 Propranolol
3 Endoscopic Treatment Alone Versus Combined Propranolol and Endoscopic Treatment of Acute Variceal Hemorrhage in Patients With Hepatocellular Carcinoma Unknown status NCT01451658 Phase 4 propranolol
4 Treatment for Prevention of Variceal Rebleeding Guided by the Hemodynamic Response Unknown status NCT00563602 Phase 4
5 Hemodynamic Effect of Simvastatin With Beta Blockers in Clinical Portal Hypertension Unknown status NCT01282385 Phase 4 Simvastatin;placebo
6 PROPRANOLOL PLUS LIGATION REDUCES RECURRENCE OF ESOPHAGEAL VARICES? Completed NCT01893541 Phase 4 PROPRANOLOL
7 Time Interval for Endoscopic Variceal Ligation Completed NCT01291277 Phase 4
8 Hemodynamic Effects of Terlipressin and High Dose Octreotide Completed NCT02119884 Phase 4 Terlipressin;Octreotide
9 A Randomized Controlled Trial Comparing Band Ligation and Cyanoacrylate Injection for Esophageal Varices Completed NCT00799851 Phase 4 cyanoacrylate injection
10 EVL (Endoscopic Variceal Ligation) Plus Vasoconstrictor vs.Ligation Plus PPI( Proton Pump Inhibitor) in the Control of Acute Esophageal Variceal Bleeding Completed NCT01112852 Phase 4 pantoloc 40 mg;somatostatin or terlipressin
11 The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed Completed NCT00534677 Phase 4 Terlipressin;Octreotide
12 A Trial of Nadolol Plus Isosorbide Mononitrate Versus Carvedilol for the Prevention of Variceal Rebleeding Completed NCT01103154 Phase 4 carvedilol;nadolol + ISMN
13 Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal Completed NCT01059396 Phase 4 propranolol;carvedilol;placebo
14 Short Course Terlipressin for Control of Acute Variceal Bleeding Completed NCT00369694 Phase 4 Terlipressin;Terlipressin & then Dummy
15 A Trial of Ligation Plus Nadolol Versus Nadolol Alone in the Prophylaxis of First Variceal Bleeding in Cirrhosis Completed NCT00921349 Phase 4 Nadolol
16 Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy Completed NCT00570973 Phase 4
17 EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment Recruiting NCT00966082 Phase 4
18 Endoscopic Band Ligation (EBL) Versus Endoscopic Band Ligation and Propranolol for the Prevention of Variceal Rebleeding Recruiting NCT00966121 Phase 4
19 Effect of Entecavir Treatment on Regression and Disease Outcome in HBV-induced Liver Fibrosis and Cirrhosis Patients Recruiting NCT02849132 Phase 4 Entecavir
20 Early Precise Diagnosis and Intervention of CPT Based on a Noninvasive 3D-vHPS Recruiting NCT02925975 Phase 4 Carvedilol
21 Efficacity and Safety of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding Recruiting NCT03023189 Phase 4 Tranexamic acid;Placebo
22 Optimized Treatment and Regression of HBV-induced Compensated Liver Cirrhosis Recruiting NCT01943617 Phase 4 Entecavir;Thymosin-α
23 Endoscopic Band Ligation (EBL) Versus Propranolol for Primary Prophylaxis of Variceal Bleeding Recruiting NCT00965900 Phase 4 Propranolol
24 Efficacy and Safety Study of Tenofovir Disoproxil Fumarate (TDF) in Chinese Chronic Hepatitis B (CHB) Subjects With Advanced Fibrosis & Compensated Cirrhosis Active, not recruiting NCT02224456 Phase 4 Tenofovir disoproxil fumarate
25 Effect of Administration of Rifaximin on the Portal Pressure of Patients With Liver Cirrhosis and Esophageal Varices Unknown status NCT02508623 Phase 3 Rifaximin;Placebo
26 Rifaximin and Propranolol Combination Therapy Versus Propranolol Monotherapy in Cirrhotic Patients Unknown status NCT01897051 Phase 2, Phase 3 Rifaximin + propranolol;Propranolol + Placebo
27 Probiotics for Portal Hypertension Unknown status NCT01134692 Phase 3 Propranolol, Norfloxacin, VSL#3
28 ABMSC Infusion Through Hepatic Artery in Portal Hypertension Surgery for the Treatment of Liver Cirrhosis Unknown status NCT01560845 Phase 2, Phase 3
29 To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites Unknown status NCT02649335 Phase 3 Propranolol
30 Efficacy and Safety of Endoscopic Injection of Fibrin Sealant Versus Endoscopic Ligature for Bleeding Esophageal Varices Completed NCT00161915 Phase 3 Fibrin Sealant
31 Danish Carvedilol Study in Portal Hypertension Completed NCT00493480 Phase 3 carvedilol;propranolol
32 Prevention of Esophageal Varices by Beta-Adrenergic Blockers Completed NCT00006398 Phase 3 Timolol Maleate;Placebo
33 Comparison of Endoscopic Variceal Ligation (EVL) With Propranolol in Non Cirrhotic Portal Hypertension (NCPH) Completed NCT01000779 Phase 3 Propranolol
34 Simvastatin Effect on Portal Hypertension Completed NCT02134626 Phase 3 Simvastatin;Placebo pill
35 Self-expandable Esophageal Stent Versus Balloon Tamponade in Refractory Esophageal Variceal Bleeding. Completed NCT01242280 Phase 3
36 Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope Completed NCT01131962 Phase 3
37 Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleeding Completed NCT00331188 Phase 3 Sanvar® (vapreotide)
38 Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding Completed NCT01095185 Phase 3 Simvastatin;Placebo
39 Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis Completed NCT01654731 Phase 3 Bezafibrate;placebo
40 Hepatic Venous Pressure Gradient-guided Versus Standard Beta-blocker Therapy in Primary Prevention of Variceal Bleeding Recruiting NCT01618890 Phase 3
41 Scleroligation for Eradication of Gastroesophageal Varices. Recruiting NCT02646202 Phase 3
42 TIPS for Variceal Rebleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis and CTPV Recruiting NCT02853526 Phase 3 Propranolol;Warfarin
43 Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis Recruiting NCT02643212 Phase 3 Rivaroxaban;Placebo
44 Endoscopic Injection Sclerotherapy Versus N-butyl-2-cyanoacrylate Injection Active, not recruiting NCT03388125 Phase 3 Injection Sclerotherapy;N-butyl-2-cyanoacrylate
45 Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients Suspended NCT02271295 Phase 3 Enoxaparine
46 Beta Blockers Versus Variceal Band Ligation and Beta Blockers for Primary Prophylaxis of Variceal Bleeding Terminated NCT00409084 Phase 3
47 Banding Versus Propranolol for Primary Prophylaxis of Variceal Bleeding Terminated NCT00337740 Phase 3 propranolol
48 Enhancing Detection of Small Esophageal Varices by PillCam ESO Withdrawn NCT00911131 Phase 3
49 Carvedilol vs Band Ligation vs Combination Therapy for Primary Prophylaxis of Variceal Bleeding Withdrawn NCT02066649 Phase 3 Carvedilol
50 Efficacy of Long-acting Octreotide (Sandostatin LAR) in Reducing Portal Pressure in Patients With Cirrhosis Completed NCT01188733 Phase 1, Phase 2 Long acting octreotide 10mg;Long acting Octreotide 30mg;Saline

Search NIH Clinical Center for Esophageal Varix

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Genetic Tests for Esophageal Varix

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Genetic tests related to Esophageal Varix:

# Genetic test Affiliating Genes
1 Esophageal Varix 29
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Anatomical Context for Esophageal Varix

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MalaCards organs/tissues related to Esophageal Varix:

41
Liver, Spleen, Testes, Heart, Brain, Endothelial, Colon
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Publications for Esophageal Varix

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Articles related to Esophageal Varix:

(show top 50) (show all 194)
# Title Authors Year
1
Esophageal Varix in an Adult Fontan Survivor. ( 29021468 )
2017
2
Successful endoscopic submucosal dissection for superficial esophageal cancer on solitary esophageal varix. ( 28576395 )
2017
3
Narrow-band imaging can increase the visibility of fibrin caps after bleeding of esophageal varices: a case with extensive esophageal candidiasis. ( 28500570 )
2017
4
Noninvasive assessment of portal hypertension and detection of esophageal varices in cirrhosis: state-of-the-art. ( 28079668 )
2017
5
Role of Serum Soluble CD163 in the Diagnosis, Risk of Bleeding, and Prognosis of Gastro-Esophageal Varices in Cirrhotic Patients. ( 28282272 )
2017
6
Pulmonary vein stenosis with collateralization via esophageal varices: Long-term follow-up after successful treatment with drug-eluting stent. ( 28924998 )
2017
7
Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices. ( 28883247 )
2017
8
Direct reopening of the occluded hepatic veins of Budd-Chiari syndrome: verification of our operative method by the perioperative course of esophageal varices. ( 28828590 )
2017
9
Association of Endoscopic Esophageal Variceal Ligation with Duodenal Ulcer. ( 27097695 )
2016
10
Pneumatic dilation for achalasia in a patient with esophageal varices. ( 27092328 )
2016
11
Massive Esophageal Variceal Bleeding as a Rare Complication of Sickle Cell Anemia. ( 26958556 )
2016
12
Regression of esophageal varices and splenomegaly in two patients with hepatitis-C-related liver cirrhosis after interferon and ribavirin combination therapy. ( 27572075 )
2016
13
A Prospective Randomized Study on the Risk of Bacteremia in Banding versus Sclerotherapy of Esophageal Varices. ( 27200352 )
2016
14
Use of Wireless Capsule Endoscopy for the Diagnosis and Grading of Esophageal Varices in Patients With Portal Hypertension: A Systematic Review and Meta-Analysis. ( 27548729 )
2016
15
Diagnostic Performance of Shear Wave Elastography for Predicting Esophageal Varices in Patients With Compensated Liver Cirrhosis. ( 27208198 )
2016
16
Prediction of esophageal varices in biliary atresia: Derivation of the "varices prediction rule", a novel noninvasive predictor. ( 25783386 )
2015
17
von Willebrand factor as a novel noninvasive predictor of portal hypertension and esophageal varices in hepatitis B patients with cirrhosis. ( 25877661 )
2015
18
Sclerotherapy Of Esophageal Varices In Severe Hemophilia A Patient And High Titer Inhibitor--Case Report. ( 26812842 )
2015
19
Asymptomatic esophageal varices in a case of pseudoxanthoma elasticum. ( 26904459 )
2015
20
Hepatic peribiliary cysts with rapidly progressive refractory obstructive jaundice and esophageal varices. ( 25748954 )
2015
21
Real-time two-dimensional shear wave ultrasound elastography of the liver is a reliable predictor of clinical outcomes and the presence of esophageal varices in patients with compensated liver cirrhosis. ( 26526884 )
2015
22
Low risk of bacteremia after endoscopic variceal therapy for esophageal varices: a systematic review and meta-analysis. ( 26528494 )
2015
23
Advanced Cirrhosis Combined with Portal Vein Thrombosis: A Randomized Trial of TIPS versus Endoscopic Band Ligation Plus Propranolol for the Prevention of Recurrent Esophageal Variceal Bleeding. ( 25759969 )
2015
24
Esophageal varix predictive performance of lower esophageal Doppler signals during the swallowing process. ( 24951299 )
2014
25
Emergency treatment of esophageal varix incarceration in the endoscope and ligation device during endoscopic variceal rubber band ligation. ( 25550983 )
2014
26
Gastrointestinal: Hepatocellular carcinoma in an esophageal varix. ( 25404106 )
2014
27
Pregnancy and delivery in women with esophageal varices due to hepatic vein thrombosis. ( 24670239 )
2014
28
Vascular lesion in an adult mimicking esophageal varix. ( 23159366 )
2013
29
Extended hemangioma from pharynx to esophagus that could be misdiagnosed as an esophageal varix on endoscopy. ( 24164602 )
2013
30
Noninvasive methods for prediction of esophageal varices in pediatric patients with portal hypertension. ( 23599624 )
2013
31
Stroke after percutaneous transhepatic variceal obliteration of esophageal varix in Caroli syndrome. ( 24348664 )
2013
32
Liver stiffness measurement by fibroscan predicts the presence and size of esophageal varices in egyptian patients with HCV related liver cirrhosis. ( 24298490 )
2013
33
A randomized controlled study of fuzheng huayu capsule for prevention of esophageal variceal bleeding in patients with liver cirrhosis. ( 23762144 )
2013
34
Pulmonary-esophageal variceal bleeding: a unique presentation of partial cor triatriatum sinistrum. ( 24367736 )
2013
35
Indocyanine green retention test as a noninvasive marker of portal hypertension and esophageal varices in compensated liver cirrhosis. ( 24038116 )
2013
36
Esophageal variceal bleeding caused by posterior mediastinal Castleman's disease. ( 23375529 )
2013
37
Combined platelet count with sCD163 and genetic variants optimizes esophageal varices prediction in cirrhotic patients. ( 22849380 )
2013
38
Elevation of the AST to ALT ratio in association with the severity of esophageal varices in patients with HCV-related compensated liver cirrhosis. ( 22975583 )
2013
39
Non-invasive ultrasound-based diagnosis and staging of esophageal varices in liver cirrhosis. A systematic review of the literature published in the third millenium. ( 23702501 )
2013
40
Diameters of left gastric vein and its originating vein on magnetic resonance imaging in liver cirrhosis patients with hepatitis B: Association with endoscopic grades of esophageal varices. ( 24107109 )
2013
41
Evolutional profile of the esophageal varices after splenectomy associated with ligation of the left gastric vein and sclerotherapy in schistosomal portal hypertension. ( 23702871 )
2013
42
Antiviral therapy delays esophageal variceal bleeding in hepatitis B virus-related cirrhosis. ( 24187460 )
2013
43
Assessment of risk of bleeding from esophageal varices during management of biliary atresia in children. ( 23263589 )
2013
44
Are different cut-off values of liver stiffness assessed by transient elastography according to the etiology of liver cirrhosis for predicting significant esophageal varices? ( 23702500 )
2013
45
Accuracy of Spleen Stiffness Measurement in Detection of Esophageal Varices in Patients With Chronic Liver Disease: Systematic Review and Meta-analysis. ( 24055985 )
2013
46
A rare cause of bleeding esophageal varices: AlstrAPm syndrome. ( 22521123 )
2012
47
Less-invasive MR indices of clinically evident esophageal variceal bleeding in biliary atresia patients. ( 23021504 )
2012
48
Transjugular intrahepatic porto-systemic stent-shunt for therapy of bleeding esophageal varices due to extramedullary hematopoiesis in primary myelofibrosis: a case report. ( 22722458 )
2012
49
Measurement of spleen stiffness to evaluate portal hypertension and the presence of esophageal varices in patients with HCV-related cirrhosis. ( 22643348 )
2012
50
Efficacy of transient elastography in screening for large esophageal varices in patients with suspicious or proven liver cirrhosis. ( 22788929 )
2012
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Variations for Esophageal Varix

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Expression for Esophageal Varix

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Search GEO for disease gene expression data for Esophageal Varix.
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Pathways for Esophageal Varix

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Pathways related to Esophageal Varix according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
FOXA2 and FOXA3 transcription factor networks 1
10.44 AFP ALB F2
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GO Terms for Esophageal Varix

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Cellular components related to Esophageal Varix according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 AFP ALB ATP4A F2 SERPINC1 SST
2 blood microparticle GO:0072562 9.33 ALB F2 SERPINC1
3 endoplasmic reticulum lumen GO:0005788 9.02 AFP ALB EOGT F2 SERPINC1

Biological processes related to Esophageal Varix according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium ion transport GO:0006814 9.54 ATP12A ATP4A SLC4A4
2 potassium ion import GO:0010107 9.46 ATP12A ATP4A
3 ATP hydrolysis coupled proton transport GO:0015991 9.43 ATP12A ATP4A
4 cellular sodium ion homeostasis GO:0006883 9.4 ATP12A ATP4A
5 cellular potassium ion homeostasis GO:0030007 9.32 ATP12A ATP4A
6 sodium ion export across plasma membrane GO:0036376 9.26 ATP12A ATP4A
7 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP12A ATP4A
8 regulation of blood coagulation GO:0030193 8.96 F2 SERPINC1
9 cellular protein metabolic process GO:0044267 8.92 AFP ALB F2 SERPINC1

Molecular functions related to Esophageal Varix according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A
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Sources for Esophageal Varix

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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