MCID: ESP016
MIFTS: 27

Esophagus Melanoma

Categories: Cancer diseases, Gastrointestinal diseases, Skin diseases

Aliases & Classifications for Esophagus Melanoma

MalaCards integrated aliases for Esophagus Melanoma:

Name: Esophagus Melanoma 12 15
Melanoma of Esophagus 12
Esophageal Melanoma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:1108
NCIt 49 C5707
UMLS 71 C1333460

Summaries for Esophagus Melanoma

MalaCards based summary : Esophagus Melanoma, also known as melanoma of esophagus, is related to melanoma and cardiac rupture. An important gene associated with Esophagus Melanoma is CDX1 (Caudal Type Homeobox 1), and among its related pathways/superpathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and IL-17 Family Signaling Pathways. Affiliated tissues include lung, liver and skin.

Related Diseases for Esophagus Melanoma

Diseases related to Esophagus Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 179)
# Related Disease Score Top Affiliating Genes
1 melanoma 10.2
2 cardiac rupture 10.2 S100A8 CXCL8
3 chlamydia pneumonia 10.2 S100A8 CXCL8
4 dysphagia 10.1
5 pancreatic vasoactive intestinal peptide producing tumor 10.0 ATP4A ATP12A
6 hemangioma of intra-abdominal structure 10.0 ATP4A ATP12A
7 displacement of cardia through esophageal hiatus 10.0 ATP4A ATP12A
8 gastric hemangioma 10.0 ATP4A ATP12A
9 acquired gastric outlet stenosis 10.0 ATP4A ATP12A
10 angiodysplasia of intestine 10.0 ATP4A ATP12A
11 angiodysplasia 10.0 ATP4A ATP12A
12 benzylpenicillin allergy 10.0 ATP4A ATP12A
13 median arcuate ligament syndrome 10.0 ATP4A ATP12A
14 granulomatous gastritis 10.0 ATP4A ATP12A
15 bacterial esophagitis 10.0 ATP4A ATP12A
16 lingual goiter 10.0 ATP4A ATP12A
17 cascade stomach 10.0 ATP4A ATP12A
18 gastrojejunal ulcer 10.0 ATP4A ATP12A
19 fungal esophagitis 10.0 ATP4A ATP12A
20 gastric gastrinoma 10.0 ATP4A ATP12A
21 superior mesenteric artery syndrome 10.0 ATP4A ATP12A
22 cervix erosion 10.0 ATP4A ATP12A
23 pneumatosis cystoides intestinalis 10.0 ATP4A ATP12A
24 dieulafoy lesion 10.0 ATP4A ATP12A
25 esophagus sarcoma 10.0 ATP4A ATP12A
26 polyposis, skin pigmentation, alopecia, and fingernail changes 10.0 ATP4A ATP12A
27 erythema multiforme 10.0 FAS CXCL8
28 necrotizing gastritis 10.0 ATP4A ATP12A
29 central nervous system origin vertigo 10.0 ATP4A ATP12A
30 chronic laryngitis 10.0 ATP4A ATP12A
31 cefuroxime allergy 10.0 ATP4A ATP12A
32 chronic intestinal vascular insufficiency 10.0 ATP4A ATP12A
33 rumination disorder 10.0 ATP4A ATP12A
34 blind loop syndrome 10.0 ATP4A ATP12A
35 crab allergy 10.0 ATP4A ATP12A
36 acute laryngitis 10.0 ATP4A ATP12A
37 duodenal gastrinoma 10.0 ATP4A ATP12A
38 esophageal tuberculosis 10.0 ATP4A ATP12A
39 gastric dilatation 10.0 ATP4A ATP12A
40 diclofenac allergy 10.0 ATP4A ATP12A
41 rosacea 10.0 S100A8 CXCL8
42 internal hemorrhoid 10.0 ATP4A ATP12A
43 duodenal obstruction 10.0 ATP4A ATP12A
44 functional diarrhea 10.0 ATP12A ATP4A
45 gastritis, familial giant hypertrophic 10.0 ATP4A ATP12A
46 pancreatic gastrinoma 10.0 ATP4A ATP12A
47 eosinophilic gastritis 10.0 ATP4A ATP12A
48 gastric antral vascular ectasia 10.0 ATP4A ATP12A
49 gastroduodenal crohn's disease 10.0 ATP4A ATP12A
50 barbiturate abuse 10.0 ATP4A ATP12A

Graphical network of the top 20 diseases related to Esophagus Melanoma:



Diseases related to Esophagus Melanoma

Symptoms & Phenotypes for Esophagus Melanoma

Drugs & Therapeutics for Esophagus Melanoma

Search Clinical Trials , NIH Clinical Center for Esophagus Melanoma

Genetic Tests for Esophagus Melanoma

Anatomical Context for Esophagus Melanoma

MalaCards organs/tissues related to Esophagus Melanoma:

40
Lung, Liver, Skin, Bone, Cervix, Monocytes, B Cells

Publications for Esophagus Melanoma

Articles related to Esophagus Melanoma:

(show all 24)
# Title Authors PMID Year
1
Primary Melanoma of Esophagus Mimicking a Carcinoma. 61
31910636 2020
2
Cardiac tamponade as an initial presentation of papillary carcinoma with psammoma bodies and intranuclear grooves-A diagnostic dilemma. 61
31120622 2019
3
Primary malignant melanoma of esophagus: clinicopathologic characterization of 20 cases including molecular genetic profiling of 15 tumors. 61
30760858 2019
4
Primary amelanotic malignant melanoma of the esophagus: a case report. 61
30635729 2019
5
Primary malignant melanoma of esophagus shared similar genetic characters with both cutaneous and oral mucosal melanoma. 61
30023129 2018
6
Clinicopathological characteristics, staging classification, and survival outcomes of primary malignant melanoma of the esophagus. 61
29266237 2018
7
Primary malignant melanoma of esophagus following chemoradiotherapy for esophageal squamous cell carcinoma: report of a case. 61
28550655 2017
8
Image of the Month: Primary Multifocal Malignant Melanoma of Esophagus Co-Occurs With Esophagogastric Junction Adenocarcinoma. 61
27018109 2016
9
Primary Spindle Cell Malignant Melanoma of Esophagus: An Unusual Finding. 61
27042502 2016
10
Primary malignant melanoma of esophagus: a case report and review of literature. 61
25550869 2014
11
Primary malignant melanoma of esophagus treated with endoscopic mucosal resection and esophagectomy. 61
21103955 2011
12
Expression of PAX8 in normal and neoplastic tissues: a comprehensive immunohistochemical study. 61
21285870 2011
13
[A case of recurrent malignant melanoma of esophagus responsive to combined chemotherapy, radiotherapy and cellular immunotherapy]. 61
21498995 2011
14
[Primary malignant melanoma of the esophagus--detection of circulating tumor cells]. 61
20716882 2010
15
[Primary malignant melanoma of esophagus: report of a case]. 61
19489230 2009
16
[Diagnostic and therapeutic difficulties in a patient with primary malignant melanoma of the esophagus--case report]. 61
15690707 2004
17
[Primary melanoma of the esophagus. Unusual case with Barrett's esophagus]. 61
11917448 2001
18
[Leptomeningeal carcinomatosis as presenting symptom of a gallbladder carcinoma]. 61
10870198 2000
19
Primary malignant melanoma of esophagus. 61
17586935 1994
20
Comparison of radionuclide bone scans and magnetic resonance imaging in detecting spinal metastases. 61
8254410 1993
21
Primary malignant melanoma of esophagus. 61
1916958 1991
22
[Production of monoclonal antibodies specific to human lung cancer--squamous cell carcinoma and adenocarcinoma]. 61
6521722 1984
23
[Primary malignant melanoma of the esophagus associated with melanosis of the esophagus and stomach]. 61
6535357 1984
24
Secondary malignant melanoma of esophagus and its treatment. 61
13974833 1962

Variations for Esophagus Melanoma

Expression for Esophagus Melanoma

Search GEO for disease gene expression data for Esophagus Melanoma.

Pathways for Esophagus Melanoma

Pathways related to Esophagus Melanoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.98 IL1B FAS CXCL8 ATP4A ATP12A
2
Show member pathways
11.67 S100A8 IL1B CXCL8
3 11.44 IL1B FAS CXCL8
4 11.1 IL1B CXCL8
5 11.06 IL1B CXCL8
6
Show member pathways
11.02 IL1B FAS CXCL8
7 10.82 IL1B FAS

GO Terms for Esophagus Melanoma

Biological processes related to Esophagus Melanoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion import across plasma membrane GO:1990573 9.37 ATP4A ATP12A
2 cellular sodium ion homeostasis GO:0006883 9.32 ATP4A ATP12A
3 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.26 ATP4A ATP12A
4 sodium ion export across plasma membrane GO:0036376 9.16 ATP4A ATP12A
5 cellular potassium ion homeostasis GO:0030007 8.96 ATP4A ATP12A
6 neutrophil chemotaxis GO:0030593 8.8 S100A8 IL1B CXCL8

Molecular functions related to Esophagus Melanoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Esophagus Melanoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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