MCID: ETH001
MIFTS: 33

Ethmoid Sinus Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Ethmoid Sinus Adenocarcinoma

MalaCards integrated aliases for Ethmoid Sinus Adenocarcinoma:

Name: Ethmoid Sinus Adenocarcinoma 12 15 74
Adenocarcinoma of the Ethmoid Sinus 12
Adenocarcinoma of Ethmoid Sinus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2766
NCIt 51 C6237
UMLS 74 C1333472

Summaries for Ethmoid Sinus Adenocarcinoma

Disease Ontology : 12 An ethmoid sinus cancer that derives from epithelial cells of glandular origin.

MalaCards based summary : Ethmoid Sinus Adenocarcinoma, also known as adenocarcinoma of the ethmoid sinus, is related to adenocarcinoma and squamous cell carcinoma of the oral tongue, and has symptoms including pain and rhinorrhea. An important gene associated with Ethmoid Sinus Adenocarcinoma is KIDINS220 (Kinase D Interacting Substrate 220), and among its related pathways/superpathways are Proteoglycans in cancer and Copper homeostasis. The drug Anesthetics has been mentioned in the context of this disorder. Affiliated tissues include breast, and related phenotype is cardiovascular system.

Related Diseases for Ethmoid Sinus Adenocarcinoma

Graphical network of the top 20 diseases related to Ethmoid Sinus Adenocarcinoma:



Diseases related to Ethmoid Sinus Adenocarcinoma

Symptoms & Phenotypes for Ethmoid Sinus Adenocarcinoma

UMLS symptoms related to Ethmoid Sinus Adenocarcinoma:


pain, rhinorrhea

MGI Mouse Phenotypes related to Ethmoid Sinus Adenocarcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.1 CCND1 CTTN KIDINS220 NDUFS3 PIK3CA SNCA

Drugs & Therapeutics for Ethmoid Sinus Adenocarcinoma

Drugs for Ethmoid Sinus Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anesthetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Mechanisms of Cancerogenesis of Woodworkers Adenocarcinomas Completed NCT02818231

Search NIH Clinical Center for Ethmoid Sinus Adenocarcinoma

Genetic Tests for Ethmoid Sinus Adenocarcinoma

Anatomical Context for Ethmoid Sinus Adenocarcinoma

MalaCards organs/tissues related to Ethmoid Sinus Adenocarcinoma:

42
Breast

Publications for Ethmoid Sinus Adenocarcinoma

Articles related to Ethmoid Sinus Adenocarcinoma:

(show all 15)
# Title Authors Year
1
Liver metastasis of ethmoid sinus adenocarcinoma. ( 25577139 )
2015
2
Advanced ethmoid sinus adenocarcinoma presenting as temporary exudative retinal detachment. ( 23898291 )
2013
3
Leptomeningeal carcinomatosis from ethmoid sinus adenocarcinoma. ( 23273418 )
2012
4
Intestinal type adenocarcinoma of the ethmoid sinus in wood and leather workers: a retrospective study of 153 cases. ( 20665741 )
2011
5
Adenocarcinoma of the ethmoid sinus: retrospective study of 42 cases. ( 21616740 )
2011
6
Survival for ethmoid sinus adenocarcinoma in European populations. ( 19363711 )
2009
7
Leptomeningeal metastases from ethmoid sinus adenocarcinoma: clinico-radiological correlation. ( 10670169 )
1999
8
ras gene mutations in ethmoid sinus adenocarcinoma: prognostic implications. ( 10421261 )
1999
9
Cisplatin-based neoadjuvant chemotherapy and combined resection for ethmoid sinus adenocarcinoma reaching and/or invading the skull base. ( 8663951 )
1996
10
Orbital presentation of ethmoid sinus adenocarcinoma. ( 8751129 )
1995
11
Adenocarcinoma of the ethmoid sinus. ( 7672971 )
1995
12
Ethmoid sinus adenocarcinoma metastatic to breast. ( 7311554 )
1981
13
Adenocarcinoma of the ethmoid sinus; report of an unusual case. ( 13112365 )
1953
14
Adenocarcinoma of the ethmoid sinus. ( 20243504 )
1947
15
Adenocarcinoma of the ethmoid sinus. ( 21014588 )
1946

Variations for Ethmoid Sinus Adenocarcinoma

Expression for Ethmoid Sinus Adenocarcinoma

Search GEO for disease gene expression data for Ethmoid Sinus Adenocarcinoma.

Pathways for Ethmoid Sinus Adenocarcinoma

GO Terms for Ethmoid Sinus Adenocarcinoma

Cellular components related to Ethmoid Sinus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial respiratory chain complex I GO:0005747 8.62 NDUFS3 SNCA

Biological processes related to Ethmoid Sinus Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.65 GGT1 GGT2 SNCA
2 cellular amino acid metabolic process GO:0006520 9.54 GGT1 GGT2
3 response to estradiol GO:0032355 9.54 CCND1 GGT1 GGT2
4 glutathione metabolic process GO:0006749 9.52 GGT1 GGT2
5 response to tumor necrosis factor GO:0034612 9.51 GGT1 GGT2
6 positive regulation of release of sequestered calcium ion into cytosol GO:0051281 9.49 CXCL11 SNCA
7 glutamate metabolic process GO:0006536 9.46 GGT1 GGT2
8 zymogen activation GO:0031638 9.43 GGT1 GGT2
9 response to magnesium ion GO:0032026 9.4 CCND1 SNCA
10 cysteine biosynthetic process GO:0019344 9.32 GGT1 GGT2
11 regulation of immune system process GO:0002682 9.26 GGT1 GGT2
12 peptide modification GO:0031179 9.16 GGT1 GGT2
13 glutathione catabolic process GO:0006751 9.13 GGT1 GGT2 GGTLC3
14 leukotriene D4 biosynthetic process GO:1901750 8.8 GGT1 GGT2 GGTLC3

Molecular functions related to Ethmoid Sinus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyltransferase activity GO:0000048 8.96 GGT1 GGT2
2 glutathione hydrolase activity GO:0036374 8.8 GGT1 GGT2 GGTLC3

Sources for Ethmoid Sinus Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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