MCID: ETH008
MIFTS: 37

Ethmoid Sinus Cancer

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Ethmoid Sinus Cancer

MalaCards integrated aliases for Ethmoid Sinus Cancer:

Name: Ethmoid Sinus Cancer 12 15
Neoplasm of Ethmoidal Sinus 12 73
Malignant Neoplasm of Ethmoidal Sinus 12
Malignant Tumor of Ethmoidal Sinus 12
Malignant Tumor of Ethmoid Sinus 12
Ethmoidal Sinus Neoplasm 12
Tumor of Ethmoidal Sinus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1363 DOID:1364
ICD10 33 C31.1
ICD9CM 35 160.3
NCIt 50 C3541 C4416
SNOMED-CT 68 93787005

Summaries for Ethmoid Sinus Cancer

MalaCards based summary : Ethmoid Sinus Cancer, also known as neoplasm of ethmoidal sinus, is related to ethmoid sinus adenocarcinoma and sinus cancer. An important gene associated with Ethmoid Sinus Cancer is NDUFS3 (NADH:Ubiquinone Oxidoreductase Core Subunit S3), and among its related pathways/superpathways are CCR5 Pathway in Macrophages and MicroRNAs in cancer. Affiliated tissues include lung, skin and colon, and related phenotypes are cardiovascular system and growth/size/body region

Related Diseases for Ethmoid Sinus Cancer

Diseases related to Ethmoid Sinus Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 ethmoid sinus adenocarcinoma 30.2 CCND1 CTTN CXCL11 GGT1 GGT2 HRAS
2 sinus cancer 10.5
3 squamous cell carcinoma of the oral tongue 10.1 CCND1 PIK3CA
4 hemimegalencephaly 10.1 CCND1 PIK3CA
5 apocrine adenoma 10.1 HRAS PIK3CA
6 prostate adenoid cystic carcinoma 10.1 HRAS PIK3CA
7 aggressive digital papillary adenocarcinoma 10.1 HRAS PIK3CA
8 lung adenoid cystic carcinoma 10.1 HRAS PIK3CA
9 acneiform dermatitis 10.0 HRAS PIK3CA
10 adenosquamous lung carcinoma 10.0 HRAS PIK3CA
11 penile cancer 10.0 CCND1 PIK3CA
12 nasal cavity adenocarcinoma 10.0 CXCL11 HRAS
13 ovary adenocarcinoma 10.0 HRAS PIK3CA
14 skin squamous cell carcinoma 10.0 HRAS PIK3CA
15 malignant ovarian surface epithelial-stromal neoplasm 10.0 HRAS PIK3CA
16 ovary epithelial cancer 10.0 HRAS PIK3CA
17 intestinal benign neoplasm 10.0 CCND1 HRAS
18 cyclosporiasis 9.9 GGT1 GGT2
19 algoneurodystrophy 9.9 GGT1 GGT2
20 pancreatic cystadenocarcinoma 9.9 GGT1 GGT2
21 hepatic tuberculosis 9.9 GGT1 GGT2
22 cataract 31, multiple types 9.9 GGT1 GGT2
23 autoimmune disease of urogenital tract 9.9 GGT1 GGT2
24 vertebrobasilar insufficiency 9.9 GGT1 GGT2
25 adenocarcinoma 9.9 CCND1 HRAS PIK3CA
26 cholangiocarcinoma 9.9 CCND1 GGT1 PIK3CA
27 nevus, epidermal 9.9 HRAS PIK3CA
28 respiratory system cancer 9.9 CCND1 HRAS PIK3CA
29 intestinal disease 9.9 CCND1 HRAS PIK3CA
30 gastrointestinal system cancer 9.9 CCND1 HRAS PIK3CA
31 pancreas adenocarcinoma 9.9 CCND1 HRAS PIK3CA
32 bladder urothelial carcinoma 9.9 CCND1 HRAS PIK3CA
33 urinary tract obstruction 9.8 GGT1 PIK3CA
34 bile duct disease 9.8 GGT1 GGT2
35 large intestine cancer 9.8 CCND1 HRAS PIK3CA
36 adenoid cystic carcinoma 9.8 CCND1 CTTN HRAS PIK3CA
37 squamous cell carcinoma, head and neck 9.8 CCND1 CTTN HRAS PIK3CA
38 squamous cell carcinoma 9.8 CCND1 CTTN HRAS PIK3CA
39 nasopharyngeal carcinoma 9.7 CCND1 HRAS PIK3CA
40 periampullary adenoma 9.7 GGT1 GGT2 HRAS
41 colloid carcinoma of the pancreas 9.7 GGT1 GGT2 HRAS
42 pancreatic cancer 9.6 CCND1 GGT1 HRAS PIK3CA
43 hepatocellular carcinoma 9.5 CCND1 CTTN GGT1 HRAS PIK3CA
44 gastrointestinal system disease 9.5 CCND1 GGT1 GGT2 HRAS

Graphical network of the top 20 diseases related to Ethmoid Sinus Cancer:



Diseases related to Ethmoid Sinus Cancer

Symptoms & Phenotypes for Ethmoid Sinus Cancer

MGI Mouse Phenotypes related to Ethmoid Sinus Cancer:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.43 CCND1 CTTN HRAS NDUFS3 PIK3CA SNCA
2 growth/size/body region MP:0005378 9.17 CCND1 CTTN GGT1 HRAS NDUFS3 PIK3CA

Drugs & Therapeutics for Ethmoid Sinus Cancer

Search Clinical Trials , NIH Clinical Center for Ethmoid Sinus Cancer

Genetic Tests for Ethmoid Sinus Cancer

Anatomical Context for Ethmoid Sinus Cancer

MalaCards organs/tissues related to Ethmoid Sinus Cancer:

41
Lung, Skin, Colon, Tongue, Breast, Ovary, Pancreas

Publications for Ethmoid Sinus Cancer

Articles related to Ethmoid Sinus Cancer:

(show all 11)
# Title Authors Year
1
Dosimetric comparison between coplanar and non coplanar field radiotherapy for ethmoid sinus cancer. ( 17877793 )
2007
2
Comparison of dose-volume histograms of IMRT treatment plans for ethmoid sinus cancer computed by advanced treatment planning systems including Monte Carlo. ( 17113671 )
2006
3
Subtotal nasal reconstruction for ethmoid sinus cancer defect using a fibula osteocutaneous free flap. ( 16894490 )
2006
4
Ethmoid sinus cancer: results of treatment with surgery and combined therapy. ( 15768822 )
2004
5
Report of a study on IMRT planning strategies for ethmoid sinus cancer. ( 12386789 )
2002
6
Intensity modulation technique using the complementary boost-fields for ethmoid sinus cancer. ( 12109830 )
2002
7
An implementation strategy for IMRT of ethmoid sinus cancer with bilateral sparing of the optic pathways. ( 11567805 )
2001
8
Ethmoid sinus cancer: twenty-nine cases managed with primary radiation therapy. ( 9607352 )
1998
9
Factors influencing survival in ethmoid sinus cancer. ( 1313248 )
1992
10
Transcranial resection of ethmoid sinus cancer involving the anterior skull base. ( 17170870 )
1992
11
Ethmoid sinus cancer. ( 5066624 )
1972

Variations for Ethmoid Sinus Cancer

Expression for Ethmoid Sinus Cancer

Search GEO for disease gene expression data for Ethmoid Sinus Cancer.

Pathways for Ethmoid Sinus Cancer

Pathways related to Ethmoid Sinus Cancer according to GeneCards Suite gene sharing:

(show all 38)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.55 CCND1 CXCL11 HRAS PIK3CA
2 12.33 CCND1 HRAS PIK3CA
3
Show member pathways
12.29 CCND1 HRAS PIK3CA
4
Show member pathways
12.28 CCND1 HRAS PIK3CA
5
Show member pathways
12.23 CCND1 HRAS PIK3CA
6
Show member pathways
12.21 CCND1 HRAS PIK3CA
7 12.21 CCND1 HRAS PIK3CA
8
Show member pathways
12.18 CCND1 HRAS PIK3CA
9
Show member pathways
12.09 CCND1 HRAS PIK3CA
10
Show member pathways
12.08 CCND1 HRAS PIK3CA
11 12.04 CCND1 HRAS PIK3CA
12
Show member pathways
12 CCND1 HRAS PIK3CA
13 11.87 CCND1 HRAS PIK3CA
14 11.86 CCND1 HRAS PIK3CA
15
Show member pathways
11.77 CCND1 HRAS PIK3CA
16
Show member pathways
11.72 CCND1 HRAS PIK3CA
17 11.56 CCND1 HRAS PIK3CA
18 11.56 CCND1 CTTN HRAS PIK3CA
19 11.49 CCND1 HRAS PIK3CA
20 11.34 CTTN PIK3CA
21 11.33 CCND1 HRAS PIK3CA
22
Show member pathways
11.31 GGT1 GGT2
23 11.29 HRAS PIK3CA
24
Show member pathways
11.23 CCND1 HRAS PIK3CA
25 11.22 HRAS PIK3CA
26 11.21 HRAS PIK3CA
27 11.15 CXCL11 PIK3CA
28 11.13 CTTN PIK3CA
29 11.11 CCND1 PIK3CA
30 11.09 HRAS PIK3CA
31 11.07 HRAS PIK3CA
32 11.01 HRAS PIK3CA
33 10.93 GGT1 GGT2
34 10.89 GGT1 GGT2
35 10.87 CCND1 HRAS
36 10.71 HRAS PIK3CA
37 10.32 CCND1 CTTN PIK3CA
38 10.12 HRAS PIK3CA

GO Terms for Ethmoid Sinus Cancer

Biological processes related to Ethmoid Sinus Cancer according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.67 GGT1 GGT2 SNCA
2 negative regulation of neuron apoptotic process GO:0043524 9.61 HRAS PIK3CA SNCA
3 cellular amino acid metabolic process GO:0006520 9.56 GGT1 GGT2
4 glutathione metabolic process GO:0006749 9.55 GGT1 GGT2
5 response to tumor necrosis factor GO:0034612 9.54 GGT1 GGT2
6 positive regulation of release of sequestered calcium ion into cytosol GO:0051281 9.52 CXCL11 SNCA
7 regulation of long-term neuronal synaptic plasticity GO:0048169 9.51 HRAS SNCA
8 response to estradiol GO:0032355 9.5 CCND1 GGT1 GGT2
9 glutamate metabolic process GO:0006536 9.48 GGT1 GGT2
10 zymogen activation GO:0031638 9.46 GGT1 GGT2
11 response to magnesium ion GO:0032026 9.4 CCND1 SNCA
12 glutathione catabolic process GO:0006751 9.37 GGT1 GGT2
13 leukotriene D4 biosynthetic process GO:1901750 9.26 GGT1 GGT2
14 cysteine biosynthetic process GO:0019344 9.16 GGT1 GGT2
15 regulation of immune system process GO:0002682 8.96 GGT1 GGT2
16 peptide modification GO:0031179 8.62 GGT1 GGT2

Molecular functions related to Ethmoid Sinus Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glutathione hydrolase activity GO:0036374 8.96 GGT1 GGT2
2 peptidyltransferase activity GO:0000048 8.62 GGT1 GGT2

Sources for Ethmoid Sinus Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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