MCID: ETH009
MIFTS: 30

Ethmoid Sinusitis

Categories: Respiratory diseases

Aliases & Classifications for Ethmoid Sinusitis

MalaCards integrated aliases for Ethmoid Sinusitis:

Name: Ethmoid Sinusitis 12 43 15 17 71
Ethmoidal Sinusitis 12
Ethmoiditis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9507
MeSH 43 D015521
NCIt 49 C34597
SNOMED-CT 67 18643000
ICD10 32 J32.2
UMLS 71 C0015029

Summaries for Ethmoid Sinusitis

Disease Ontology : 12 A sinusitis which involves infection of ethmoid sinuses that causes pain or pressure behind and between the eyes, tearing, and headache over the forehead.

MalaCards based summary : Ethmoid Sinusitis, also known as ethmoidal sinusitis, is related to chronic ethmoiditis and paranasal sinus disease. An important gene associated with Ethmoid Sinusitis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1). The drugs Hyaluronic acid and mometasone furoate have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and brain.

Related Diseases for Ethmoid Sinusitis

Diseases related to Ethmoid Sinusitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 491)
# Related Disease Score Top Affiliating Genes
1 chronic ethmoiditis 34.2 RHNO1 MUC7
2 paranasal sinus disease 31.5 RHNO1 PRTN3 OAF CRP
3 cavernous sinus thrombosis 30.5 RHNO1 CRP
4 acute dacryocystitis 30.4 RHNO1 DCXR
5 subdural empyema 30.3 RHNO1 CRP
6 orbital cellulitis 30.3 RHNO1 CRP
7 exophthalmos 30.0 RHNO1 PRTN3 CRP
8 acute maxillary sinusitis 30.0 RHNO1 CRP
9 atrophic rhinitis 30.0 RHNO1 DCXR
10 maxillary sinusitis 29.9 PRTN3 OAF CRP
11 mastoiditis 29.8 PRTN3 CRP
12 middle ear disease 29.8 PRTN3 CRP
13 scleritis 29.7 PRTN3 CRP
14 posterior scleritis 29.7 PRTN3 CRP
15 cranial nerve palsy 29.6 RHNO1 PRTN3 CRP
16 igg4-related disease 29.5 PRTN3 CRP
17 frontal sinusitis 29.4 SNORD60 RHNO1 OAF DCXR
18 multiple cranial nerve palsy 29.3 RHNO1 PRTN3 CRP
19 orbital disease 29.3 RHNO1 PRTN3 CRP
20 ethmoid sinus squamous cell carcinoma 12.6
21 acute ethmoiditis 12.4
22 ethmoid sinus inverted papilloma 12.4
23 ethmoid sinus adenoid cystic carcinoma 12.3
24 ethmoidal sinus neoplasm 12.2
25 ethmoid sinus schneiderian papilloma 12.2
26 ethmoid sinus ectopic meningioma 12.2
27 meningoencephalocele 11.6
28 olfactory neuroblastoma 11.4
29 adenocarcinoma 10.4
30 ossifying fibroma 10.4
31 meningioma, radiation-induced 10.4
32 meningioma, familial 10.4
33 spinal meningioma 10.4
34 secretory meningioma 10.4
35 lymphoplasmacyte-rich meningioma 10.4
36 sarcoma 10.4
37 spindle cell sarcoma 10.4
38 encephalocele 10.4
39 yemenite deaf-blind hypopigmentation syndrome 10.4
40 aneurysmal bone cysts 10.3
41 fibrous dysplasia 10.3
42 meningitis 10.3
43 excessive tearing 10.3 RHNO1 DCXR
44 maxillary sinus inverted papilloma 10.3 RHNO1 DCXR
45 glossopharyngeal nerve disease 10.3 RHNO1 CRP
46 intracranial sinus thrombosis 10.3 RHNO1 CRP
47 acute orbital inflammation 10.3 RHNO1 CRP
48 osteogenic sarcoma 10.3
49 external ear disease 10.3 RHNO1 CRP
50 cerebritis 10.3 RHNO1 CRP

Graphical network of the top 20 diseases related to Ethmoid Sinusitis:



Diseases related to Ethmoid Sinusitis

Symptoms & Phenotypes for Ethmoid Sinusitis

Drugs & Therapeutics for Ethmoid Sinusitis

Drugs for Ethmoid Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
2
mometasone furoate Approved, Investigational, Vet_approved Phase 4 83919-23-7
3 Anti-Inflammatory Agents Phase 4
4 Dermatologic Agents Phase 4
5 Anti-Allergic Agents Phase 4
6
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
7
Ofloxacin Approved Phase 3 82419-36-1 4583
8 Antibiotics, Antitubercular Phase 3
9 Anti-Bacterial Agents Phase 3
10 Anti-Infective Agents Phase 3
11 Cytochrome P-450 Enzyme Inhibitors Phase 3
12 Antitubercular Agents Phase 3
13 Renal Agents Phase 3
14 Topoisomerase Inhibitors Phase 3
15 Anti-Infective Agents, Urinary Phase 3
16 Cytochrome P-450 CYP1A2 Inhibitors Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Prospective, Multi-Center, Randomized, Controlled, Subject-Blinded Study to Evaluate the Safety and Effectiveness of AdvaCoat Sinus Gel Following Endoscopic Ethmoid Sinus Surgery Completed NCT00554190 Phase 4
2 The PIO II Study: A Randomized, Controlled, Blinded Trial to Evaluate the Safety and Efficacy of In-office Placement of a Steroid-eluting Sinus Implant Post-ethmoidectomy Completed NCT02668302 Phase 4
3 Gel-Sinuplasty for Chronic Rhinosinusitis With and Without Nasal Polyposis Recruiting NCT03472144 Phase 3 gel loaded with steroids (momentasone);gel loaded with antibiotic (Levofloxacin);gel loaded with both steroids and antibiotic
4 Interventioanl Study of the Sinopsys® Lacrimal Stent in Patients With Moderate to Severe Chronic Rhinosinusitis to Evaluate Safety and Performance for Direct Ethmoid Sinus Saline Irrigation and Ophthalmic Antibiotic/Steroid Delivery Completed NCT03304951
5 The Sinopsys Lacrimal Stent Indicated for Sinus Irrigation Via Transcaruncular Ethmoid Sinus Access in Patients With Moderate to Severe Chronic Rhinosinusitis With Ethmoid Sinus Involvement Completed NCT02297243 Early Phase 1

Search NIH Clinical Center for Ethmoid Sinusitis

Cochrane evidence based reviews: ethmoid sinusitis

Genetic Tests for Ethmoid Sinusitis

Anatomical Context for Ethmoid Sinusitis

MalaCards organs/tissues related to Ethmoid Sinusitis:

40
Eye, Bone, Brain, Breast, Thyroid, B Cells, Colon

Publications for Ethmoid Sinusitis

Articles related to Ethmoid Sinusitis:

(show top 50) (show all 296)
# Title Authors PMID Year
1
Orbital complication of acute ethmoiditis: A Tunisian paediatric cross sectional study. 61
31732307 2020
2
Optic Neuropathy, Secondary to Ethmoiditis, and Onodi Cell Inflammation during Childhood: A Case Report and Review of the Literature. 61
31330559 2019
3
[Recurrent orbital complication by rhinosinusitis. A case report]. 61
31758908 2019
4
Schizophyllum commune sinusitis after allogeneic bone marrow transplantation for myelodysplastic syndrome: A case report and literature review. 61
31674700 2019
5
Surgical Approaches in the Treatment of Intracranial Complications of Paranasal Sinus Disease: A Review of the Literature. 61
31254711 2019
6
What Is the Best Treatment for a Subperiosteal Abscess? A Case Report in a Pediatric Patient. 61
30871969 2019
7
Anesthetic considerations during surgical intervention in Woake's syndrome -a case report. 61
29764007 2019
8
Acellular dermal matrix contributes to epithelialization in patients with chronic sinusitis. 61
30651053 2019
9
[Acute ethmoid sinusitis complicated by a retrobulbar abscess in a 13-year-old child]. 61
30853144 2019
10
Malignant peripheral nerve sheath tumor of the nasal cavity and nasopharynx in a child: A case report. 61
30681599 2019
11
Clinical Case Presentation on Absence Seizures Diagnosis and Treatment Care Services and Outcomes in an Adult Patient. 61
30765995 2019
12
Bilateral subdural empyemas with meningitis secondary to acute barosinusitis. 61
30337240 2018
13
Septic Cavernous Sinus Thrombosis Following a Minor Head Injury: A Rare Cause of Medico-Legal Death. 61
29464700 2018
14
Microbiology and antibiotic therapy of subperiosteal orbital abscess in children with acute ethmoiditis. 61
29447900 2018
15
Enhanced Irrigant Delivery to the Ethmoid Sinuses Directly Following Ethmoid Punch Sinusotomy. 61
29047295 2017
16
Antimicrobial treatment of ENT infections. 61
29290238 2017
17
A prospective, randomized clinical study comparing drug eluting stent therapy and intranasal corticoid steroid therapy in the treatment of patients with chronic rhinosinusitis. 61
28492612 2017
18
Safe treatment of ethmoid sinusitis utilizing minimally invasive ethmoid punch sinusotomy in chronic rhinosinusitis without polyposis patients. 61
28194802 2017
19
Metastatic Colon Cancer to the Sphenoid Wing and Ethmoid Sinus Mimicking Orbital Cellulitis: A Rare Presentation. 61
26974420 2017
20
Ethmoiditis with subperiosteal and retro-ocular abscesses due to Aeromonas sobria in a 16-year-old boy exposed to the Ardèche river. 61
28343158 2017
21
Radiologic findings of Fusarium pneumonia in neutropenic patients. 61
27470138 2017
22
The "black evil" affecting patients with diabetes: a case of rhino orbito cerebral mucormycosis causing Garcin syndrome. 61
28405168 2017
23
Primary ciliary dyskinesia presenting with spontaneous pneumothorax: Case report and review of the literature. 61
28616378 2017
24
Topographic relationship; sinusitis and paranasal sinus computed tomography. 61
29553614 2016
25
Trends in chronic rhinosinusitis research in the past three decades. 61
26256105 2016
26
Relationship between dacryoadenitis subtype of idiopathic orbital inflammatory pseudotumor and paranasal sinusitis. 61
27158618 2016
27
Pediatric sinogenic epidural and subdural empyema: The role of endoscopic sinus surgery. 61
26304070 2015
28
Extra middle turbinate lamellas: a suggested new classification. 61
25616850 2015
29
Image-guided, navigation-assisted Relieva Stratus MicroFlow Spacer insertion into the ethmoid sinus. 61
25325931 2015
30
Primary acquired nasolacrimal duct obstruction: is it really related to paranasal abnormalities? 61
25422096 2015
31
Nocardia asteroides sinusitis in a pediatric patient: Case report with 20 year follow-up and review of the literature. 61
25943955 2015
32
Orbital necrotizing fasciitis and osteomyelitis caused by arcanobacterium haemolyticum: a case report. 61
24801256 2015
33
The role of osteitis of the lamina papyracea in the formation of subperiosteal orbital abscess in young children. 61
25465453 2014
34
[Orbital complications of sinusitis]. 61
25640234 2014
35
Primary ciliary dyskinesia complicated with diffuse panbronchiolitis: a case report and literature review. 61
24308375 2014
36
A novel therapeutic use of HFA-BDP metereddose inhaler for asthmatic patients with rhinosinusitis: Case series. 61
25074867 2014
37
Frequency of the odontogenic maxillary sinusitis extended to the anterior ethmoid sinus and response to surgical treatment. 61
24608208 2014
38
Ossifying fibroma of the middle turbinate revealed by infection in a young child. 61
24139075 2014
39
[Orbital alveolar rhabdomyosarcoma masked by ethmoid sinusitis in a 25-year-old]. 61
24269390 2014
40
Step-by-step iconographic description of a prolonged but still favourable course of orbital cellulitis in a child with acute rhinosinusitis: an iconographic case study. 61
24594215 2014
41
Neonatal orbital abscess. 61
24008806 2014
42
[Pediatric orbital cellulitis without sinusitis: report of four cases]. 61
24239218 2014
43
[The influence of local and combined acute suppurative Highmore maxillary sinusitis on the serum lactoferrin and interleukin-8 levels in the children]. 61
25588485 2014
44
[Septic cavernous sinus thrombosis following ethmoiditis: a case report]. 61
24290188 2014
45
Inflammation of the frontal intersinus septal air cell as a cause of headaches. 61
25485764 2014
46
[A childhood nasopharyngeal carcinoma with huge mass in skull base]. 61
24459938 2013
47
A case of Schizophyllum commune sinusitis following unrelated cord blood transplantation for acute lymphoblastic leukemia. 61
23686329 2013
48
Orbital apex syndrome as a sign of unsuspected breast carcinoma. 61
23851836 2013
49
[Endoscopic treatment of orbital cellulitis in pediatric patients: transethmoidal approach]. 61
23768475 2013
50
[Aspergillus ethmoiditis associated with orbital abscess]. 61
23685133 2013

Variations for Ethmoid Sinusitis

Expression for Ethmoid Sinusitis

Search GEO for disease gene expression data for Ethmoid Sinusitis.

Pathways for Ethmoid Sinusitis

GO Terms for Ethmoid Sinusitis

Sources for Ethmoid Sinusitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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