MCID: ETH012
MIFTS: 21

Ethylene Glycol Poisoning

Categories: Rare diseases

Aliases & Classifications for Ethylene Glycol Poisoning

MalaCards integrated aliases for Ethylene Glycol Poisoning:

Name: Ethylene Glycol Poisoning 59

Characteristics:

Orphanet epidemiological data:

59
ethylene glycol poisoning
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age;

Classifications:



External Ids:

Orphanet 59 ORPHA31826
UMLS via Orphanet 74 C0413194
ICD10 via Orphanet 34 T52.8

Summaries for Ethylene Glycol Poisoning

MalaCards based summary : Ethylene Glycol Poisoning is related to metabolic acidosis and lactic acidosis. An important gene associated with Ethylene Glycol Poisoning is AKR1A1 (Aldo-Keto Reductase Family 1 Member A1). The drugs Fomepizole and Antidotes have been mentioned in the context of this disorder. Affiliated tissues include kidney, brain and liver.

Wikipedia : 76 Ethylene glycol poisoning is poisoning caused by drinking ethylene glycol. Early symptoms include... more...

Related Diseases for Ethylene Glycol Poisoning

Diseases related to Ethylene Glycol Poisoning via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 metabolic acidosis 10.3
2 lactic acidosis 10.1
3 hypophosphatemia 10.0
4 cerebritis 10.0
5 peripheral nervous system disease 10.0
6 inherited metabolic disorder 10.0
7 myocarditis 10.0
8 peritonitis 10.0
9 neuropathy 10.0

Graphical network of the top 20 diseases related to Ethylene Glycol Poisoning:



Diseases related to Ethylene Glycol Poisoning

Symptoms & Phenotypes for Ethylene Glycol Poisoning

Drugs & Therapeutics for Ethylene Glycol Poisoning

Drugs for Ethylene Glycol Poisoning (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fomepizole Approved, Vet_approved 7554-65-6 3406
2 Antidotes
3 Protective Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Specified Drug-use Survey of Fomepizole Intravenous Infusion (All-case Surveillance) Recruiting NCT02415712 Fomepizole

Search NIH Clinical Center for Ethylene Glycol Poisoning

Genetic Tests for Ethylene Glycol Poisoning

Anatomical Context for Ethylene Glycol Poisoning

MalaCards organs/tissues related to Ethylene Glycol Poisoning:

41
Kidney, Brain, Liver, Testes

Publications for Ethylene Glycol Poisoning

Articles related to Ethylene Glycol Poisoning:

(show top 50) (show all 209)
# Title Authors Year
1
Recurrent Ethylene Glycol Poisoning with Elevated Lactate Levels to Obtain Opioid Medications. ( 29627349 )
2018
2
Lactate gap as a tool in identifying ethylene glycol poisoning. ( 29525762 )
2018
3
Rapid Diagnosis of Ethylene Glycol Poisoning by Urine Microscopy. ( 29899323 )
2018
4
Simplifying the hemodialysis prescription in patients with ethylene glycol poisoning. ( 28709598 )
2017
5
Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning? ( 29038192 )
2017
6
Serum Calcium Concentration in Ethylene Glycol Poisoning. ( 28083813 )
2017
7
Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation. ( 29026875 )
2017
8
Effect of repeated administration of 4-methylpyrazole on renal function and lipid peroxidation products in rat kidney after ethylene glycol poisoning. ( 29091817 )
2017
9
Sequential episodes of ethylene glycol poisoning in the same person. ( 28551601 )
2017
10
Prediction and validation of the duration of hemodialysis sessions for the treatment of acuteA ethylene glycol poisoning. ( 28412021 )
2017
11
Calcium oxalate monohydrate crystals in ethylene glycol poisoning. ( 27590893 )
2016
12
Ethylene Glycol Poisoning: An Unusual Cause of Altered Mental Status and the Lessons Learned from Management of the Disease in the Acute Setting. ( 27847651 )
2016
13
Assessment of a semi-quantitative screening method for diagnosis of ethylene glycol poisoning. ( 27687084 )
2016
14
Ethylene glycol poisoning in three dogs: Importance of early diagnosis and role of hemodialysis as a treatment option. ( 27145686 )
2016
15
Brain magnetic resonance image changes following acute ethylene glycol poisoning. ( 26588653 )
2015
16
Ethylene glycol poisoning in sheep. ( 25977491 )
2015
17
Ethylene glycol poisoning. ( 26265865 )
2015
18
Hemodiafiltration efficacy in treatment of methanol and ethylene glycol poisoning in a 2-year-old girl. ( 26384118 )
2015
19
Positive propylene glycol result in a patient with ethylene glycol poisoning. ( 24682690 )
2014
20
False hyperlactatemia in life-threatening ethylene glycol poisoning. ( 24630168 )
2014
21
Predictors of Death and Prolonged Renal Insufficiency in Ethylene Glycol Poisoning. ( 24371252 )
2013
22
Ethylene glycol poisoning: quintessential clinical toxicology; analytical conundrum. ( 23063961 )
2013
23
Falsely increased plasma lactate concentration due to ethylene glycol poisoning in 2 dogs. ( 23356706 )
2013
24
Massive Ethylene Glycol Poisoning Triggers Osmotic Demyelination Syndrome. ( 24199725 )
2013
25
An enzymatic assay for the detection of glycolic acid in serum as a marker of ethylene glycol poisoning. ( 24263643 )
2013
26
Unusual clinical presentation of ethylene glycol poisoning: unilateral facial nerve paralysis. ( 24307904 )
2013
27
Challenges in the diagnosis of ethylene glycol poisoning. ( 24215789 )
2013
28
Gastric aspirate fluorescence in ethylene glycol poisoning. ( 22975284 )
2012
29
Antifreeze on a freezing morning: ethylene glycol poisoning in a 2-year-old. ( 22605809 )
2012
30
Ethylene glycol poisoning: a rare but life-threatening cause of metabolic acidosis-a single-centre experience. ( 25503773 )
2012
31
Ethylene glycol poisoning and the lactate gap. ( 22321092 )
2012
32
Ethylene glycol poisoning and the osmolal gap. ( 22775380 )
2012
33
Neuroimaging findings in acute ethylene glycol poisoning. ( 22883652 )
2012
34
Acute oxalate nephropathy caused by ethylene glycol poisoning. ( 26889430 )
2012
35
Ethylene glycol poisoning: quintessential clinical toxicology; analytical conundrum. ( 22085425 )
2012
36
Studies on ethylene glycol poisoning: one patient - 154 admissions. ( 21824058 )
2011
37
Calcium oxalate monohydrate crystals: a clue to ethylene glycol poisoning. ( 20571351 )
2011
38
Laboratory diagnosis of ethylene glycol poisoning: the cup is half full? ( 21757590 )
2011
39
Outcomes with bilateral cochlear implantation following sudden dual sensory loss after ethylene glycol poisoning. ( 21917206 )
2011
40
Intentional ethylene glycol poisoning increase after media coverage of antifreeze murders. ( 21731785 )
2011
41
Medication errors associated with the use of ethanol and fomepizole as antidotes for methanol and ethylene glycol poisoning. ( 21740138 )
2011
42
The lactate gap revisited: variable interference with lactate analyses in ethylene glycol poisoning. ( 20973412 )
2010
43
Delayed ethylene glycol poisoning presenting with abdominal pain and multiple cranial and peripheral neuropathies: a case report. ( 20663174 )
2010
44
Successful outcome of accidental ethylene glycol poisoning despite delayed presentation. ( 22767560 )
2010
45
Elevated lactate in ethylene glycol poisoning: True or false? ( 20096388 )
2010
46
Early and late presentations of ethylene glycol poisoning. ( 19272685 )
2009
47
Ethylene glycol poisoning presenting with a falsely elevated lactate level. ( 19016054 )
2009
48
Ethylene glycol poisoning and lactate concentrations. ( 19796512 )
2009
49
Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning? ( 19852621 )
2009
50
Relationship between serum glycolate and falsely elevated lactate in severe ethylene glycol poisoning. ( 19371468 )
2009

Variations for Ethylene Glycol Poisoning

Expression for Ethylene Glycol Poisoning

Search GEO for disease gene expression data for Ethylene Glycol Poisoning.

Pathways for Ethylene Glycol Poisoning

GO Terms for Ethylene Glycol Poisoning

Sources for Ethylene Glycol Poisoning

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....