MCID: EXR007
MIFTS: 26

Exercise-Induced Anaphylaxis

Categories: Rare diseases

Aliases & Classifications for Exercise-Induced Anaphylaxis

MalaCards integrated aliases for Exercise-Induced Anaphylaxis:

Name: Exercise-Induced Anaphylaxis 53
Exercise Anaphylaxis 73

Classifications:



External Ids:

UMLS 73 C0344183

Summaries for Exercise-Induced Anaphylaxis

NIH Rare Diseases : 53 Exercise-induced anaphylaxis (EIAn) is a rare disorder in which anaphylaxis occurs in association with physical activity. Food-dependent exercise-induced anaphylaxis is a subset of this disorder in which symptoms develop if exertion takes place within a few hours of eating a specific food. In the case of food-dependent exercise-induced anaphylaxis, neither the food nor the exercise alone is enough to cause anaphylaxis. Vigorous forms of physical activity, such as jogging, are more commonly associated with exercise-induced anaphylaxis, although lower levels of exertion (eg, walking and yard work) are also capable of triggering attacks. However, the condition can be unpredictable; a given level of exercise may cause an episode on one occasion but not another. Symptoms of exercise-induced anaphylaxis may include itching, hives (urticaria), flushing, extreme fatigue, and wheezing. Affected individuals may also experience nausea, abdominal cramping, and diarrhea. Continuing the physical activity causes the symptoms to become worse. However, if the individual stops the activity when the symptoms first appear, there is usually improvement within minutes. In most cases, these conditions are sporadic , though familial cases have been reported.

MalaCards based summary : Exercise-Induced Anaphylaxis, also known as exercise anaphylaxis, is related to urticaria and cholinergic urticaria. An important gene associated with Exercise-Induced Anaphylaxis is CD79A (CD79a Molecule), and among its related pathways/superpathways are Immune response Fc epsilon RI pathway and NF-kappaB Signaling. Affiliated tissues include testes, skin and liver.

Wikipedia : 76 Exercise-Induced Anaphylaxis (EIAn) is a rare condition in which anaphylaxis, a serious or... more...

Related Diseases for Exercise-Induced Anaphylaxis

Diseases related to Exercise-Induced Anaphylaxis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 urticaria 10.4
2 cholinergic urticaria 10.3
3 syncope 10.2
4 asthma 10.1
5 amoxicillin allergy 10.0 ENPP3 IGHE
6 immunoglobulin g deficiency 10.0 CD79A IGHE
7 ocular toxoplasmosis 10.0 CD79A IGHE
8 immunodeficiency with hyper-igm, type 1 10.0 CD79A IGHE
9 helicobacter pylori infection 10.0
10 ventricular fibrillation, paroxysmal familial, 1 10.0
11 myocardial infarction 10.0
12 acute myocardial infarction 10.0
13 dental caries 10.0
14 food allergy 10.0
15 ischemia 10.0
16 wheat allergy 10.0
17 allergic hypersensitivity disease 9.9 ENPP3 IGHE
18 otitis media 9.9 CD79A IGHE
19 latex allergy 9.9 FLG IGHE
20 nut allergy 9.9 ENPP3 FLG
21 peanut allergy 9.9 FLG IGHE
22 orofacial granulomatosis 9.8 CD79A FLG
23 dermatitis 9.8 FLG IGHE
24 dermatitis, atopic 9.8 FLG IGHE
25 skin disease 9.6 CD79A FLG

Graphical network of the top 20 diseases related to Exercise-Induced Anaphylaxis:



Diseases related to Exercise-Induced Anaphylaxis

Symptoms & Phenotypes for Exercise-Induced Anaphylaxis

Drugs & Therapeutics for Exercise-Induced Anaphylaxis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clonal Mast Cell Disorders in Exercise-Induced Anaphylaxis Unknown status NCT01326741
2 The Impact of High Intensity Exercise Upon EPC Number and Function in Young Women Unknown status NCT01314573 Not Applicable
3 Major Allergen in Wheat Anaphylaxis in Thai Population Completed NCT03487315 Not Applicable

Search NIH Clinical Center for Exercise-Induced Anaphylaxis

Genetic Tests for Exercise-Induced Anaphylaxis

Anatomical Context for Exercise-Induced Anaphylaxis

MalaCards organs/tissues related to Exercise-Induced Anaphylaxis:

41
Testes, Skin, Liver

Publications for Exercise-Induced Anaphylaxis

Articles related to Exercise-Induced Anaphylaxis:

(show top 50) (show all 245)
# Title Authors Year
1
Data on various allergen specific IgEs and prospective treatments on food-dependent exercise-induced anaphylaxis. ( 29904693 )
2018
2
Food-dependent exercise-induced anaphylaxis to soybean. ( 29802905 )
2018
3
Food-dependent exercise-induced anaphylaxis in Japanese elementary school children. ( 29341364 )
2018
4
Food-dependent exercise-induced anaphylaxis due to almond in a PR-10-sensitized patient. ( 29397370 )
2018
5
Exercise Lowers Threshold and Increases Severity, but Wheat-Dependent, Exercise-Induced Anaphylaxis Can Be Elicited at Rest. ( 29524997 )
2018
6
Food-dependent exercise-induced anaphylaxis. ( 29643134 )
2018
7
A Multicenter Evaluation of Diagnosis and Management of Omega-5 Gliadin Allergy (Also Known as Wheat-Dependent Exercise-Induced Anaphylaxis) in 132 Adults. ( 29477569 )
2018
8
How to manage food dependent exercise induced anaphylaxis (FDEIA). ( 29629955 )
2018
9
Wheat-dependent exercise-induced anaphylaxis: Are you sure about the diagnosis? ( 30033924 )
2018
10
A New Diagnostic Criteria of Wheat-Dependent, Exercise-Induced Anaphylaxis in China. ( 30127214 )
2018
11
Exercise-induced anaphylaxis associated with the use of bee pollen. ( 30261295 )
2018
12
Food-dependent, exercise-induced anaphylaxis in a patient allergic to peach. ( 30270687 )
2018
13
An Unusual and Rare Case of Food-dependent Exercise-induced Anaphylaxis Caused by Ingestion of Potatoes. ( 30355832 )
2018
14
Exercise-Induced Anaphylaxis: Literature Review and Recent Updates. ( 30367321 )
2018
15
Allergic acute coronary syndrome in exercise-induced anaphylaxis. ( 30465657 )
2018
16
FOOD-DEPENDENT EXERCISE-INDUCED ANAPHYLAXIS DUE TO INGESTION OF MIKAN (CITRUS UNSHIU). ( 28904280 )
2017
17
Exercise-Induced Anaphylaxis in an Air Force Aviator Taking a HMG-CoA Reductase Inhibitor: A Case Report and Review of the Presentation, Diagnoses, and Treatment. ( 29087932 )
2017
18
Food-dependent, exercise-induced anaphylaxis triggered by co-incidence of culprit food, physical effort and a very high dose of ibuprofen or menstruation: a case report. ( 28261038 )
2017
19
Food-dependent exercise-induced anaphylaxis. ( 28115440 )
2017
20
An unusual case of wheat dependent exercise induced anaphylaxis (WDEIA) triggered by Tri a 14 in a pediatric patient: a case report. ( 29384105 )
2017
21
Aspirin is an enhancing factor for food-dependent exercise-induced anaphylaxis in children. ( 28892197 )
2017
22
Food-dependent exercise-induced anaphylaxis due to shrimp associated with 43A kDa, a new antigen. ( 28470776 )
2017
23
Successful treatment with omalizumab in challenge confirmed exercise-induced anaphylaxis. ( 27839749 )
2017
24
Long-term omalizumab use in the treatment of exercise-induced anaphylaxis. ( 29070274 )
2017
25
Exercise-induced anaphylaxis in an elderly patient. ( 29066661 )
2017
26
Food-Dependent, Exercise-Induced Anaphylaxis: Diagnosis and Management in the Outpatient Setting. ( 28283153 )
2017
27
Managing labour with a history of Exercise Induced Anaphylaxis. ( 26723222 )
2016
28
Diagnosis of exercise-induced anaphylaxis: current insights. ( 27822074 )
2016
29
Rye-dependent exercise-induced anaphylaxis. ( 27788890 )
2016
30
Clinical and laboratory features, and quality of life assessment in wheat dependent exercise-induced anaphylaxis patients from central China. ( 27376813 )
2016
31
Recognizing and managing food-dependent exercise-induced anaphylaxis. ( 26961453 )
2016
32
Erratum: Diagnosis of exercise-induced anaphylaxis: current insights [Corrigendum]. ( 27920561 )
2016
33
Angiotensin-converting enzyme genotype is a risk factor for wheat-dependent exercise-induced anaphylaxis sensitized with hydrolyzed wheat protein. ( 26666484 )
2016
34
Molecular characterization of the IgE-binding epitopes in the fast ω-gliadins of Triticeae in relation to wheat-dependent, exercise-induced anaphylaxis. ( 27374148 )
2016
35
Cholinergic urticaria and exercise-induced anaphylaxis. ( 25574887 )
2015
36
Wheat-Dependent Exercise-Induced Anaphylaxis. ( 26381478 )
2015
37
Food dependant exercise induced anaphylaxis a retrospective study from 2 allergy clinics in Colombo, Sri Lanka. ( 26213534 )
2015
38
Case of food-dependent exercise-induced anaphylaxis due to Japanese apricot and peach: Detection of causative antigens. ( 26047253 )
2015
39
Assessment of the Allergenic Potential of Transgenic Wheat (Triticum aestivum) with Reduced Levels of I85-Gliadins, the Major Sensitizing Allergen in Wheat-Dependent Exercise-Induced Anaphylaxis. ( 26447559 )
2015
40
Exercise-induced anaphylaxis and antileukotriene montelukast. ( 26312002 )
2015
41
Food-dependent exercise-induced anaphylaxis to chickpea in a 17-year-old female: a case report. ( 26334308 )
2015
42
Exercise-Induced Anaphylaxis. ( 25841550 )
2015
43
SIX CASES OF WHEAT-DEPENDENT EXERCISE-INDUCED ANAPHYLAXIS IN CHILDREN. ( 26522419 )
2015
44
Prevalences of specific IgE to wheat gliadin components in patients with wheat-dependent exercise-induced anaphylaxis. ( 25838103 )
2015
45
Provocation tests for the diagnosis of food-dependent exercise-induced anaphylaxis. ( 26360640 )
2015
46
Exercise-induced anaphylaxis after consumption of red meat in a patient with IgE antibodies specific for galactose-alpha-1,3-galactose. ( 26028298 )
2015
47
Food-dependent exercise-induced anaphylaxis among junior high school students: a 14-year epidemiological comparison. ( 26117264 )
2015
48
The Association Between Food and Exercise Induced Anaphylaxis. ( 26182809 )
2015
49
Study on the Immunoreactivity of Triticum monococcum (Einkorn) Wheat in Patients with Wheat-Dependent Exercise-Induced Anaphylaxis for the Production of Hypoallergenic Foods. ( 26332577 )
2015
50
Pathophysiological mechanisms of exercise-induced anaphylaxis: an EAACI position statement. ( 26100553 )
2015

Variations for Exercise-Induced Anaphylaxis

Expression for Exercise-Induced Anaphylaxis

Search GEO for disease gene expression data for Exercise-Induced Anaphylaxis.

Pathways for Exercise-Induced Anaphylaxis

GO Terms for Exercise-Induced Anaphylaxis

Cellular components related to Exercise-Induced Anaphylaxis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.8 CD79A ENPP3 IGHE

Biological processes related to Exercise-Induced Anaphylaxis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell receptor signaling pathway GO:0050853 8.62 CD79A IGHE

Sources for Exercise-Induced Anaphylaxis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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