MCID: EXR010
MIFTS: 34

Exercise-Induced Bronchoconstriction

Categories: Respiratory diseases

Aliases & Classifications for Exercise-Induced Bronchoconstriction

MalaCards integrated aliases for Exercise-Induced Bronchoconstriction:

Name: Exercise-Induced Bronchoconstriction 12
Exercise-Induced Asthma 12
Asthma Exercise-Induced 54

Classifications:



External Ids:

Disease Ontology 12 DOID:0080821

Summaries for Exercise-Induced Bronchoconstriction

Disease Ontology : 12 An intrinsic asthma that is characterized by narrowing of the airways during or shortly after exercise.

MalaCards based summary : Exercise-Induced Bronchoconstriction, also known as exercise-induced asthma, is related to ige responsiveness, atopic and allergic asthma. An important gene associated with Exercise-Induced Bronchoconstriction is ALOX5 (Arachidonate 5-Lipoxygenase), and among its related pathways/superpathways are Interleukin-4 and 13 signaling and Leukotriene modifiers pathway, Pharmacodynamics. The drugs Montelukast and Ipratropium have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, skin and smooth muscle, and related phenotype is respiratory system.

Wikipedia : 73 Exercise-induced asthma, or E.I.A., occurs when the airways narrow as a result of exercise. The... more...

Related Diseases for Exercise-Induced Bronchoconstriction

Diseases related to Exercise-Induced Bronchoconstriction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 91)
# Related Disease Score Top Affiliating Genes
1 ige responsiveness, atopic 31.1 RNASE3 IL13
2 allergic asthma 30.5 RNASE3 IL13 ALOX5
3 allergic rhinitis 30.4 RNASE3 IL13 ALOX5
4 rhinitis 30.4 RNASE3 IL13 CYSLTR1
5 hypereosinophilic syndrome 30.3 RNASE3 IL13 ALOX5
6 intrinsic asthma 30.3 RNASE3 IL13
7 conjunctivitis 30.2 RNASE3 IL13
8 pollen allergy 30.2 RNASE3 IL13
9 chronic asthma 30.1 RNASE3 IL13 ALOX5
10 acute asthma 30.1 RNASE3 ALOX5
11 allergic conjunctivitis 30.1 RNASE3 IL13
12 chronic rhinitis 30.0 RNASE3 IL13
13 bronchitis 30.0 RNASE3 IL13
14 asthma 29.7 RNASE3 IL13 CYSLTR1 ALOX5 ADIPOQ
15 proteasome-associated autoinflammatory syndrome 1 29.6 RNASE3 IL13 ALOX5 ADIPOQ
16 dermatitis, atopic 29.5 RNASE3 IL13 CYSLTR1
17 common cold 29.4 RNASE3 IL13 CYSLTR1
18 respiratory failure 29.3 THBD RNASE3 IL13 ALOX5
19 urticaria 29.1 RNASE3 IL13 CYSLTR1 ALOX5
20 lung disease 10.3
21 intermittent asthma 10.3
22 exercise-induced anaphylaxis 10.2
23 allergic disease 10.2
24 tremor 10.2
25 childhood-onset asthma 10.1 RNASE3 IL13
26 kimura disease 10.1 RNASE3 IL13
27 timothy grass allergy 10.1 RNASE3 IL13
28 vernal keratoconjunctivitis 10.1 RNASE3 IL13
29 keratoconjunctivitis 10.1 RNASE3 IL13
30 toxocariasis 10.1 RNASE3 IL13
31 paragonimiasis 10.1 RNASE3 IL13
32 vasomotor rhinitis 10.1 RNASE3 IL13
33 elephantiasis 10.1 RNASE3 IL13
34 chronic conjunctivitis 10.1 RNASE3 IL13
35 urinary schistosomiasis 10.1 RNASE3 IL13
36 schistosomiasis 10.1 RNASE3 IL13
37 latex allergy 10.1 RNASE3 IL13
38 gastroesophageal reflux 10.1
39 respiratory allergy 10.1 RNASE3 IL13
40 mercury poisoning 10.1 THBD IL13
41 esophagitis, eosinophilic, 1 10.1 RNASE3 IL13
42 esophagitis 10.1 RNASE3 IL13
43 conjunctival disease 10.1 RNASE3 IL13
44 eosinophilic pneumonia 10.1 RNASE3 IL13
45 onchocerciasis 10.0 RNASE3 IL13
46 fibrosis of extraocular muscles, congenital, 1 10.0
47 cystic fibrosis 10.0
48 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.0
49 autoimmune lymphoproliferative syndrome 10.0
50 body mass index quantitative trait locus 1 10.0

Graphical network of the top 20 diseases related to Exercise-Induced Bronchoconstriction:



Diseases related to Exercise-Induced Bronchoconstriction

Symptoms & Phenotypes for Exercise-Induced Bronchoconstriction

MGI Mouse Phenotypes related to Exercise-Induced Bronchoconstriction:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 8.92 ADIPOQ CYSLTR1 IL13 THBD

Drugs & Therapeutics for Exercise-Induced Bronchoconstriction

Drugs for Exercise-Induced Bronchoconstriction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 56)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Montelukast Approved Phase 4 158966-92-8 5281040
2
Ipratropium Approved, Experimental Phase 4 60205-81-4, 22254-24-6 43232 657309
3
Budesonide Approved Phase 4 51333-22-3 63006 5281004
4 Cholinergic Agents Phase 4
5 Hormone Antagonists Phase 4
6 Hormones Phase 4
7 Leukotriene Antagonists Phase 4
8 Anti-Inflammatory Agents Phase 4
9
Salmeterol xinafoate Phase 4 94749-08-3 56801
10 Formoterol Fumarate Phase 4
11 Anticonvulsants Phase 4
12 Bromides Phase 4
13 Cholinergic Antagonists Phase 4
14 glucocorticoids Phase 4
15
Benralizumab Approved, Investigational Phase 3 1044511-01-4
16
Procaterol Approved, Investigational Phase 3 72332-33-3 688561
17
Phenylephrine Approved Phase 3 59-42-7 6041
18
Oxymetazoline Approved, Investigational Phase 3 1491-59-4 4636
19
Ciclesonide Approved, Investigational Phase 3 126544-47-6, 141845-82-1 444033
20 Cromolyn Sodium Phase 3
21 Neurotransmitter Agents Phase 3
22 Respiratory System Agents Phase 3
23 Anti-Asthmatic Agents Phase 3
24 Albuterol Phase 3
25 Bronchodilator Agents Phase 3
26 Adrenergic Agonists Phase 3
27 Adrenergic beta-Agonists Phase 3
28 Adrenergic Agents Phase 3
29 Tocolytic Agents Phase 3
30
Terbutaline Approved Phase 2 23031-25-6 5403
31
Reproterol Investigational Phase 2 54063-54-6
32 Sympathomimetics Phase 2
33 Antibodies Phase 2
34 Immunoglobulins Phase 2
35 Antibodies, Monoclonal Phase 2
36
Vitamin C Approved, Nutraceutical Phase 1 50-81-7 5785 54670067
37 Nutrients Phase 1
38 Trace Elements Phase 1
39 Micronutrients Phase 1
40 Vitamins Phase 1
41 Antioxidants Phase 1
42 Protective Agents Phase 1
43 Soy Bean Phase 1
44
Nitric Oxide Approved 10102-43-9 145068
45
Mannitol Approved, Investigational 69-65-8 6251 453
46
Histamine Approved, Investigational 51-45-6, 75614-87-8 774
47
Capsaicin Approved 404-86-4 1548943
48
Adenosine Approved, Investigational 58-61-7 60961
49
Metformin Approved Early Phase 1 657-24-9 4091 14219
50 Muscarinic Agonists

Interventional clinical trials:

(show top 50) (show all 70)
# Name Status NCT ID Phase Drugs
1 Time-Effect of Montelukast on Protection Against Exercise-Induced Bronchoconstriction Completed NCT00935415 Phase 4 Montelukast;Placebo
2 201832: A Randomised, Double-Blind, Double-Dummy, Crossover Comparison of Fluticasone Furoate/Vilanterol 100/25 mcg Once Daily Versus Fluticasone Propionate 250 mcg Twice Daily in Adolescent and Adult Subjects With Asthma and Exercise-Induced Bronchoconstriction Completed NCT02730351 Phase 4 Fluticasone furoate/ Vilanterol 100 mcg/25 mcg;Fluticasone propionate 250 mcg;Placebo via ELLIPTA inhaler;Placebo via DISKUS / ACCUHALER
3 Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes Completed NCT01691079 Phase 4 ipratropium bromide;Placebo
4 A Double-Blind, Placebo-Controlled, Multicenter, Crossover Study to Evaluate the Effects of a Single Oral Dose of Montelukast, Compared With Placebo, on Exercise-Induced Bronchoconstriction (EIB) in Pediatric Patients Aged 4 to 14 Years Completed NCT00534976 Phase 4 Comparator: montelukast sodium;Comparator: Comparator: placebo (unspecified)
5 A Stratified, Multicenter, Randomized, Double-Blind, Parallel Group, 4-Week Comparison of Fluticasone Propionate/Salmeterol DISKUS Combination Product 100/50mcg BID Versus Fluticasone Propionate DISKUS 100mcg BID in Pediatric and Adolescent Subjects With Activity-Induced Bronchospasm Completed NCT00118716 Phase 4 Fluticasone propionate/salmeterol;Fluticasone Propionate
6 A Stratified, Multicenter, Randomized, Double-Blind, Parallel Group, 4-Week Comparison of Fluticasone Propionate/Salmeterol DISKUS Combination Product 100/50mcg BID Versus Fluticasone Propionate DISKUS 100mcg BID in Pediatric and Adolescent Subjects With Activity-Induced Bronchospasm Completed NCT00118690 Phase 4 Fluticasone propionate/salmeterol
7 "Pretreatment With Albuterol vs. Montelukast in Exercise Induced Bronchospasm in Children." Completed NCT00273689 Phase 4 montelukast vs pretreatment with albuterol;montelukast
8 A Randomized, Double-Blind Trial of the Effect of Different Anti-Asthmatic Treatments on Lung Function and on Exercise-Induced Bronchoconstriction in Children With Asthma Completed NCT00490243 Phase 4 budesonide and montelukast;budesonide and formoterol;montelukast;budesonide;placebo
9 Asthma and Childhood Obesity: Understanding Potential Mechanisms and Identifying Strategies to Improve Respiratory Symptoms Recruiting NCT03586544 Phase 4 Albuterol
10 A Randomized, Double-blind, Double Dummy Crossover Trial on the Effect of Budesonide/Formoterol and Inhaled Budesonide Alone on Exercise-Induced Asthma in Patients With Persistent Asthma Terminated NCT01070888 Phase 4 Budesonide/Formoterol;Budesonide
11 The Effect of Benralizumab on Lung Physiology, Exercise-induced Bronchoconstriction and General Health Status: an Exploratory Mechanistic Study Unknown status NCT03327701 Phase 3 Benralizumab
12 A Multicenter, Double-Blind, Randomized, Crossover Design Study to Evaluate the Effect of Montelukast Vs. Salmeterol on the Inhibition of Exercise-Induced Bronchoconstriction in Asthmatic Patients Aged 6-14 Years Completed NCT00127166 Phase 3 Montelukast sodium;Salmeterol xinafoate;Fluticasone propionate;Montelukast matching placebo;Salmeterol matching placebo
13 A Double-Blind, Randomized Multicenter, 3-Period, Crossover Study to Evaluate the Effects of a Single Dose of Montelukast Compared With Placebo and Salmeterol on Exercise-Induced Bronchoconstriction Completed NCT00245570 Phase 3 Comparator: Montelukast;Comparator: Salmeterol;Comparator: Placebo (montelukast);Comparator: Placebo (salmeterol)
14 A Randomized, Double-blind, Single-Dose, 2-Period, Crossover Study to Assess the Efficacy of PT027 Compared With Placebo on Exercise-Induced Bronchoconstriction in Adult and Adolescent Subjects With Asthma Completed NCT04234464 Phase 3
15 A Single-Dose Study to Assess the Efficacy of Albuterol SPIROMAX® in Adult and Adolescent Patients With Exercise-Induced Bronchoconstriction (EIB) Completed NCT01791972 Phase 3 Albuterol Spiromax;Placebo Spiromax
16 An Efficacy Study of Single-Dose Levalbuterol Tartrate HFA MDI Versus Placebo in Prevention of EIB in Subjects 18 Years of Age and Older With EIB Completed NCT00268723 Phase 3 Levalbuterol tartrate HFA MDI;Placebo
17 A Double-Blind, Randomized, Placebo-Controlled, Multicenter, 2-Period, Crossover Study to Evaluate the Effects of a Single Dose of Montelukast on Exercise-Induced Bronchospasm Completed NCT00090142 Phase 3 Comparator: Montelukast;Comparator: Placebo
18 A Double-Blind, Randomized, Placebo-Controlled, Multicenter, 2-Period, Crossover Study to Evaluate the Effects of a Single Dose of Montelukast on Exercise-Induced Bronchospasm Completed NCT00092131 Phase 3 Comparator: Montelukast;Comparator: Placebo
19 A Single-Dose Efficacy Comparison of Albuterol Hydrofluoroalkane (HFA) Breath-operated Inhaler (BOI) (Volare Easi-Breathe™) and Albuterol HFA Meter Dose Inhaler (MDI) (Volare™) in Adolescents and Adults With Exercise-Induced Bronchospasm Completed NCT00085774 Phase 3 albuterol aerosol by HFA MDI;albuterol aerosol by HFA BOI;placebo aerosol by HFA
20 A Randomised Double Blind, Placebo Controlled 4-way Cross Over Study Comparing Montelukast, Inhaled Budesonide and Their Combination on Exercise-induced Bronchoconstriction Completed NCT00462592 Phase 3 budesonide;montelukast
21 Effect of Ciclesonide on Exercise Induced Bronchoconstriction Completed NCT00525772 Phase 3 ciclesonide;ciclesonide
22 WP3-Influence of Cromones on EVH-test in Young (Elite) Athletes Who Tested Positive for EIB (=Exercise Induced Bronchoconstriction) Not yet recruiting NCT04408664 Phase 3 Sodium Cromoglycate;Placebo
23 Randomized, Double-Blind, Controlled, Single-Dose, Three-Treatment, Cross-Over Study of The Protective Effects Of Albuterol-HFA In Preventing Exercise-Induced Bronchoconstriction In Adolescent And Adult Asthmatic Patients Terminated NCT00634829 Phase 3 albuterol (Armstrong Albuterol HFA);Albuterol Sulfate (Provenetil-HFA);Placebo-HFA
24 Evaluation of the Bronchoprotective Effect of Arformoterol in Children With Exercise Induced Bronchospasm Withdrawn NCT00662779 Phase 3 arformoterol;formoterol;placebo
25 A Randomized, Double-Blind, Double-Dummy, Crossover Comparison of Fluticasone Furoate/Vilanterol 100/25 mcg Once Daily Versus Fluticasone Propionate 250 mcg Twice Daily in Asthmatic Adolescent and Adult Subjects With Exercise-Induced Bronchoconstriction Withdrawn NCT01435902 Phase 3 Fluticasone Furoate/Vilanterol Inhalation Powder;Fluticasone Propionate Inhalation Powder
26 A Randomised, Double Blind, Placebo Controlled, Parallel-group Study With Use of Budesonide/Formoterol "As-needed", or Terbutaline "As-needed" or Regular Use of Budesonide + Terbutaline "As-needed", in Patients With Mild Intermittent Asthma Completed NCT00989833 Phase 2 budesonide;terbutaline;budesonide/formoterol
27 Efficacy and Safety of Oglemilast in the Prevention of Exercise-Induced Bronchospasm Completed NCT00322283 Phase 2 Oglemilast;Placebo
28 A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Assess the Safety and Efficacy of Four Weeks of Oral Senicapoc Administration on Exercise-Induced Asthma Completed NCT00861185 Phase 2 senicapoc;Placebo
29 Clinical Trial to Assess the Protective Effect of the Fixed Drug Combination of Disodium Cromoglycate Plus Reproterol in Comparison to the Single Components and Placebo in Adults With Exercise Induced Asthma Randomised, Placebo-Controlled, Double-Blind, Crossover, Multicentre Study Completed NCT00777348 Phase 2 Combination DSCG and Reproterol
30 A Double-blind, Placebo-controlled, Four-way Crossover Study to Compare the Safety and Efficacy of ONO-6950 20 mg and 200 mg QD Versus Placebo and Montelukast (Singulair) in Asthmatic Patients Who Experience Exercise-induced Bronchoconstriction Completed NCT01536041 Phase 2 ONO-6950;ONO-6950;Montelukast;Placebo
31 A Multi-centre, Randomized, Double-blind, Five-way Crossover Study Evaluating the Dose Response and Duration of Action of GSK2190915 Compared to Placebo in Subjects With Mild Asthma Who Experience Exercise Induced Bronchoconstriction. Completed NCT00812929 Phase 2 Placebo;GSK2190915
32 A Phase 2A, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety and Effect on Exercise Challenge Testing of Multiple Fixed Subcutaneous Doses of MEDI-528, A Humanized Anti-Interleukin-9 Monoclonal Antibody, in Adults With Stable Asthma and Exercise-Induced Bronchoconstriction Terminated NCT00590720 Phase 2
33 A 3 Period, Double-Blind, Randomized Crossover Study to Evaluate the Effects of a Single Dose of Montelukast Compared With Placebo on Exercise-Induced Bronchoconstriction as Assessed by Hyperpolarized Gas Magnetic Resonance Imaging. Completed NCT00664937 Phase 1 montelukast sodium;Comparator: placebo (unspecified)
34 Comparative and Additive Effects of Fish Oil and Ascorbic Acid Supplementation on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma Completed NCT01057615 Phase 1
35 Mediator Release During Exercise-induced Bronchoconstriction Unknown status NCT03524053
36 Exercised-Induced Bronchoconstriction in Patients With Severe Obstructive Sleep Apnea Unknown status NCT00916773
37 Exercise-induced Bronchoconstriction in School Children - Prevalence, Environmental/Individual Risk Factors and Its Mechanism Unknown status NCT01798823
38 Exercise-induced Bronchoconstriction in a Cold Chamber Compared to Methacholine Challenge Completed NCT02026492
39 Examination of Bronchial Inflammation and Hyperresponsiveness After Oil Supplementation With Middle-chain and Polyunsaturated Fatty Acids in an Exercise-induced Asthma Provocation Model Completed NCT02410096
40 The Effects of High-dose Salbutamol on Anaerobic Cycling Power Completed NCT02255630
41 Diagnostics of the Quality of Life With Exercise Induced Asthma (EIA) and Exercise Induced Laryngeal Obstruction (EILO) Completed NCT03550456
42 A Prospective Study Measuring Exhaled Nitric Oxide in Exercise-Induced Asthma Completed NCT01097954
43 Study of Airway Inflammation in Relation to Exercise in Elite Athletes Completed NCT01942096
44 The Effects of HOST-DM059 Prebiotic Supplementation on Gut Bacterial Metabolites, and Markers of Systemic Inflammation in Adults With and Without Hyperpnoea-Induced Bronchoconstriction: A Double-Blind, Placebo-Controlled, Crossover Trial. Completed NCT02872675
45 The Use of a Heat and Moisture Exchange Mask to Reduce Exercise Induced Bronchoconstriction Severity and Improve the Airway Health of Individuals With Asthma Completed NCT04302610
46 Prevalence of Exercise-Induced Asthma in Select Cohorts of College Athletes Completed NCT00806000
47 Explorative Study "Exercise Induced Asthma and Airway Reactivity in Athletes" Completed NCT00798564
48 Exercise-induced Bronchoconstriction Diagnostics: Impact of a Repeated Exercise Challenge Test Completed NCT01214551
49 The Effect of Physical Exercise in a Cold Air Environment on Normal Volunteers and Asthmatic Patients Completed NCT03840044
50 Exercise-Induced Bronchospasm in Cystic Fibrosis Completed NCT00806455

Search NIH Clinical Center for Exercise-Induced Bronchoconstriction

Genetic Tests for Exercise-Induced Bronchoconstriction

Anatomical Context for Exercise-Induced Bronchoconstriction

MalaCards organs/tissues related to Exercise-Induced Bronchoconstriction:

40
Neutrophil, Skin, Smooth Muscle, Lung, Endothelial, Trachea, Monocytes

Publications for Exercise-Induced Bronchoconstriction

Articles related to Exercise-Induced Bronchoconstriction:

(show top 50) (show all 2172)
# Title Authors PMID Year
1
Responsiveness to montelukast is associated with bronchial hyperresponsiveness and total immunoglobulin E but not polymorphisms in the leukotriene C4 synthase and cysteinyl leukotriene receptor 1 genes in Korean children with exercise-induced asthma (EIA). 61 54
17883728 2007
2
Pharmacotherapy of diseases mediated by 5-lipoxygenase pathway eicosanoids. 54 61
17481554 2007
3
Transcription in response to physical stress--clues to the molecular mechanisms of exercise-induced asthma. 54 61
16027142 2005
4
Changes in blood levels of eosinophil cationic protein and tryptase after exercise challenge in adolescents with exercise-induced asthma. 54 61
15080512 2004
5
[A study on the role of T lymphocytes and eosinophil cationic protein in exercise-induced asthma]. 54 61
12816679 2003
6
The new phosphodiesterase 4 inhibitor roflumilast is efficacious in exercise-induced asthma and leads to suppression of LPS-stimulated TNF-alpha ex vivo. 61 54
11865966 2002
7
Comparative effects of long-acting beta2-agonists, leukotriene receptor antagonists, and a 5-lipoxygenase inhibitor on exercise-induced asthma. 61 54
10984370 2000
8
Comparison between allergen-induced and exercise-induced asthma with respect to the late asthmatic response, airway responsiveness, and Creola bodies in sputum. 61 54
8814050 1996
9
Inhibition of exercise-induced bronchospasm by zileuton: a 5-lipoxygenase inhibitor. 54 61
8630575 1996
10
Roles of eosinophils and catecholamines in pathophysiology of exercise-induced asthma. 61 54
8298715 1993
11
Eosinophils in exercise-induced asthma. 61 54
1955630 1991
12
Exercise-induced laryngeal obstruction in children and adolescents: are we listening? 61
33077532 2021
13
Asthma, atopy, and exercise: Sex differences in exercise-induced bronchoconstriction. 61
33794694 2021
14
Current Asthma Management Practices by Primary School Teaching Staff: A Systematic Review. 61
33594691 2021
15
Overweight and exercise-induced bronchoconstriction - Is there a link? 61
33683749 2021
16
Differential effects of intense exercise and pollution on the airways in a murine model. 61
33722268 2021
17
Pulmonary function as a limiting factor of middle distance race performance. 61
33565755 2021
18
Exercise-Induced Alterations in Phospholipid Hydrolysis, Airway Surfactant and Eicosanoids and their Role in Airway Hyperresponsiveness in Asthma. 61
33533300 2021
19
Exercise-induced laryngeal obstruction: From clinical examination to continuous laryngoscopy during exercise. 61
33622626 2021
20
Case Report: Mastocytosis: The Long Road to Diagnosis. 61
33643319 2021
21
Diagnostic value of bronchoprovocation challenge with adenosine monophosphate versus exercise testing in early diagnosis of asthma. 61
33487865 2021
22
Ventilatory responses to constant load exercise following the inhalation of a short-acting ß2-agonist in a laboratory-controlled diesel exhaust exposure study in individuals with exercise-induced bronchoconstriction. 61
33395924 2021
23
Exercise Induced Bronchoconstriction and Bronchodilation; investigating the effects of age, sex, airflow limitation and the FEV1. 61
33446611 2021
24
Does Cold-Water Endurance Swimming Affect Pulmonary Function in Healthy Adults? 61
33435240 2021
25
The impact of mental toughness and postural abnormalities on dysfunctional breathing in athletes. 61
33406374 2021
26
Failure to meet extubation criteria in the setting of suspected buffalo chest physiology. 61
33604576 2021
27
Does exercise-induced bronchoconstriction affect physical activity patterns in asthmatic children? 61
31607144 2020
28
Prevalence of exercise-induced bronchoconstriction and laryngeal obstruction in adolescent athletes. 61
33002318 2020
29
Effect of age on exercise-induced bronchoconstriction in children and adolescents with asthma. 61
33207980 2020
30
The Visual Analog Scale detects exercise-induced bronchoconstriction in children with asthma. 61
31482747 2020
31
Gestational and Postpartum Weight Trajectories Among Women With and Without Asthma. 61
33169142 2020
32
[Induced asthma and sport]. 61
33739762 2020
33
[Diagnostic performance of the physical activity related question of the GINA questionnaire to detect exercise-induced bronchoconstriction in asthma]. 61
33172787 2020
34
The interest of rehabilitation of respiratory disorders in athletes: Myth or reality? 61
33271343 2020
35
Determinants of exercise capacity in children and adolescents with severe therapy-resistant asthma. 61
33026845 2020
36
Sex Differences in Exercise-Induced Bronchoconstriction in Athletes: A Systematic Review and Meta-Analysis. 61
33027929 2020
37
The effect of diurnal variation in exercise-induced bronchoconstriction. 61
31274345 2020
38
The feasibility of eucapnic voluntary hyperpnoea for the diagnosis of exercise-induced bronchoconstriction in a community pulmonary practice. 61
32962464 2020
39
Anti-muscarinic drugs as preventive treatment of exercise-induced bronchoconstriction (EIB) in children and adults. 61
32911137 2020
40
Diagnosis of Exercise-induced Bronchoconstriction in Swimmers: Context Matters. 61
32175977 2020
41
Work Group Report: Perspectives in Diagnosis and Management of Exercise-Induced Bronchoconstriction in Athletes. 61
32636147 2020
42
Cut-off values to evaluate exercise-induced asthma in eucapnic voluntary hyperventilation test for children. 61
32491255 2020
43
High prevalence of exercise-induced stridor during Parkrun: a cross-sectional field-based evaluation. 61
32998911 2020
44
Exercise-induced bronchoconstriction: A survey of diagnostic practice in secondary care across the United Kingdom. 61
32249953 2020
45
The role of cardiopulmonary exercise testing in evaluating children with exercise induced dyspnoea. 61
32980274 2020
46
Cysteinyl Leukotriene Synthesis via Phospholipase A2 Group IV Mediates Exercise-induced Bronchoconstriction and Airway Remodeling. 61
32182104 2020
47
Special Considerations and Perspectives for Exercise-Induced Bronchoconstriction (EIB) in Olympic and Other Elite Athletes. 61
32006727 2020
48
Exercise-induced bronchoconstriction in elite or endurance athletes:: Pathogenesis and diagnostic considerations. 61
32035936 2020
49
Exercise Challenge to Test for Exercise-induced Bronchoconstriction. 61
32609016 2020
50
Management of Exercise-Induced Bronchoconstriction in Athletes. 61
32620432 2020

Variations for Exercise-Induced Bronchoconstriction

Expression for Exercise-Induced Bronchoconstriction

Search GEO for disease gene expression data for Exercise-Induced Bronchoconstriction.

Pathways for Exercise-Induced Bronchoconstriction

Pathways related to Exercise-Induced Bronchoconstriction according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.01 IL13 ALOX5
2 9.53 CYSLTR1 ALOX5

GO Terms for Exercise-Induced Bronchoconstriction

Cellular components related to Exercise-Induced Bronchoconstriction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.02 THBD RNASE3 IL13 ALOX5 ADIPOQ

Biological processes related to Exercise-Induced Bronchoconstriction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to ethanol GO:0045471 9.26 IL13 ADIPOQ
2 glucose homeostasis GO:0042593 9.16 ALOX5 ADIPOQ
3 positive regulation of cold-induced thermogenesis GO:0120162 8.96 IL13 ADIPOQ
4 negative regulation of inflammatory response GO:0050728 8.8 IL13 ALOX5 ADIPOQ

Sources for Exercise-Induced Bronchoconstriction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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