MCID: EXF003
MIFTS: 27

Exfoliative Dermatitis

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Exfoliative Dermatitis

MalaCards integrated aliases for Exfoliative Dermatitis:

Name: Exfoliative Dermatitis 52 17 71 32

Classifications:



External Ids:

ICD10 32 L26
UMLS 71 C0011606

Summaries for Exfoliative Dermatitis

MalaCards based summary : Exfoliative Dermatitis is related to holocarboxylase synthetase deficiency and dermatitis, and has symptoms including exanthema The drugs Sotalol and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and kidney.

Wikipedia : 74 Erythroderma is an inflammatory skin disease with redness and scaling that affects nearly the entire... more...

Related Diseases for Exfoliative Dermatitis

Diseases related to Exfoliative Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
# Related Disease Score Top Affiliating Genes
1 holocarboxylase synthetase deficiency 11.5
2 dermatitis 11.1
3 hypereosinophilic syndrome 10.4
4 pustulosis of palm and sole 10.4
5 psoriasis 10.4
6 thymoma, familial 10.3
7 exanthem 10.3
8 thymoma 10.3
9 allergic hypersensitivity disease 10.3
10 mycosis fungoides 10.2
11 erythema multiforme 10.2
12 skin disease 10.2
13 lymphoma 10.2
14 acute kidney failure 10.2
15 ritter's disease 10.2
16 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 10.2
17 severe cutaneous adverse reaction 10.1
18 interstitial nephritis 10.1
19 hepatitis 10.1
20 pulmonary tuberculosis 10.1
21 folliculitis 10.1
22 kidney disease 10.1
23 erythema multiforme major 10.1
24 hypertriglyceridemia, familial 10.0
25 leprosy 3 10.0
26 acute promyelocytic leukemia 10.0
27 leukemia 10.0
28 thrombocytopenia 10.0
29 contact dermatitis 10.0
30 congestive heart failure 10.0
31 impetigo 10.0
32 hansen's disease 10.0
33 stevens-johnson syndrome/toxic epidermal necrolysis 10.0
34 renal cell carcinoma, nonpapillary 9.9
35 systemic lupus erythematosus 9.9
36 pityriasis rubra pilaris 9.9
37 rheumatoid arthritis 9.9
38 anemia, hypochromic microcytic, with iron overload 1 9.9
39 immune deficiency disease 9.9
40 myasthenia gravis 9.9
41 ocular motor apraxia 9.9
42 graves disease 1 9.9
43 ataxia and polyneuropathy, adult-onset 9.9
44 dermatitis herpetiformis, familial 9.9
45 leukemia, acute myeloid 9.9
46 omenn syndrome 9.9
47 nail disorder, nonsyndromic congenital, 10 9.9
48 graft-versus-host disease 9.9
49 hydrops, lactic acidosis, and sideroblastic anemia 9.9
50 angina pectoris 9.9

Graphical network of the top 20 diseases related to Exfoliative Dermatitis:



Diseases related to Exfoliative Dermatitis

Symptoms & Phenotypes for Exfoliative Dermatitis

UMLS symptoms related to Exfoliative Dermatitis:


exanthema

Drugs & Therapeutics for Exfoliative Dermatitis

Drugs for Exfoliative Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 32)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sotalol Approved Phase 4 959-24-0, 3930-20-9 5253
2 Neurotransmitter Agents Phase 4
3 Sodium Channel Blockers Phase 4
4 Diuretics, Potassium Sparing Phase 4
5 Anti-Arrhythmia Agents Phase 4
6 Adrenergic Antagonists Phase 4
7 Adrenergic beta-Antagonists Phase 4
8 Autonomic Agents Phase 4
9 Sympatholytics Phase 4
10 Adrenergic Agents Phase 4
11
Minocycline Approved, Investigational Phase 1, Phase 2 10118-90-8 5281021
12
Lamotrigine Approved, Investigational Phase 2 84057-84-1 3878
13
Valproic acid Approved, Investigational Phase 2 99-66-1 3121
14
Rifaximin Approved, Investigational Phase 2 80621-81-4 6436173 46783403
15
Calcium Approved, Nutraceutical Phase 2 7440-70-2 271
16 Antipsychotic Agents Phase 2
17 Hormones Phase 2
18 Central Nervous System Depressants Phase 2
19 Anticonvulsants Phase 2
20 Tranquilizing Agents Phase 2
21 GABA Agents Phase 2
22 Calcium, Dietary Phase 2
23 calcium channel blockers Phase 2
24 Antimanic Agents Phase 2
25 Psychotropic Drugs Phase 2
26 Anti-Bacterial Agents Phase 2
27 Anti-Infective Agents Phase 2
28 Gastrointestinal Agents Phase 2
29
Miconazole Approved, Investigational, Vet_approved 22916-47-8 4189
30 Antibodies
31 Immunoglobulins
32 Immunologic Factors

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Pilot and Feasibility Study to Determine if a Common Atrial Fibrillation Risk Locus Modulates Differential Response to Antiarrhythmic Drugs Recruiting NCT02347111 Phase 4 Flecainide;Sotalol
2 A Randomised, Double Blind Pilot Study of Minocycline and Placebo Added to Treatment-as-Usual (TAU) in First-Episode Psychosis Completed NCT00916461 Phase 1, Phase 2 Minocycline;Placebo
3 A Randomized Open-Label 6 Month Acute and Maintenance Trial of Lamotrigine vs. Standard of Care Sodium Valproate Monotherapy for Treatment of Mixed Mania. Completed NCT00206778 Phase 2 Lamotrigine;Sodium Valproate
4 Pilot, Single Center, Open, Trial of Rifaximin in Probable Alzheimer's Disease Recruiting NCT03856359 Phase 2 Rifaximin 550 milligrams (MG)
5 sCD163 & CD19 as Candidate Biomarkers in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) - A Study of sCD163 in the Cerebrospinal Fluid Unknown status NCT02271724
6 Analysis of Killer Immunoglobulin-like Receptor Transcripts Expression for the Diagnosis of Epidermotropic Cutaneous T-cell Lymphomas (Mycosis Fungoid and Sézary Syndrome) in Patients With Erythroderma or Erythematous Patches/Plaques. Completed NCT00748319

Search NIH Clinical Center for Exfoliative Dermatitis

Genetic Tests for Exfoliative Dermatitis

Anatomical Context for Exfoliative Dermatitis

MalaCards organs/tissues related to Exfoliative Dermatitis:

40
Skin, T Cells, Kidney, Liver, Testes, Myeloid, Lung

Publications for Exfoliative Dermatitis

Articles related to Exfoliative Dermatitis:

(show top 50) (show all 523)
# Title Authors PMID Year
1
Lichenoid drug reaction due to anti-tubercular therapy presenting as erythroderma. 61
31747108 2020
2
Satisfactory response of a back carbuncle to 5-aminolevulinic acid (ALA) photodynamic therapy: A case report. 61
31841685 2019
3
Thymoma-associated exfoliative dermatitis in a goat: case report and brief literature review. 61
31650897 2019
4
A severe case of bevacizumab-induced thrombotic microangiopathy. 61
30253727 2019
5
Diffuse Exfoliative Rash with Sepsis and Eosinophilia: A Case of Erythroderma? 61
31541072 2019
6
A rare and severe cutaneous adverse effect of telaprevir: drug rash with eosinophilia and systemic symptoms. 61
31251007 2019
7
A previously undescribed cutaneous paraneoplastic syndrome in a cat with thymoma. 61
30908751 2019
8
Perils with Pirfenidone and "the tuberculosis link". 61
31512609 2019
9
[Lamotrigine induced hypersensitivity syndrome in children: a case report]. 61
30996382 2019
10
Dapsone Hypersensitivity Syndrome (DHS): A Detrimental Effect of Dapsone? A Case Report. 61
30062974 2019
11
Idiopathic Generalized Exfoliative Dermatitis and Association with Antihypertensive Drugs and Statins: A Retrospective Case-Control Study. 61
30716732 2019
12
Report: A case report on Nevirapine induced exfoliative dermatitis. 61
30772813 2019
13
Imatinib Mesylate Induced Erythroderma. 61
31313559 2018
14
Malnutrition and skin disease in Far East prisoners-of-war in World War II. 61
29855062 2018
15
Amoxicillin/clavulanic acid-induced exfoliative dermatitis in a child. 61
30302990 2018
16
Zinc-responsive exfoliative dermatitis in a 17-year-old girl with delayed puberty. 61
29740861 2018
17
Profile of erythroderma in children in hospital dermatology departments in Lomé, Togo : study of 28 cases. 61
30270830 2018
18
Drug Reaction with Eosinophilia and Systemic Symptoms Associated with Reactivation of Epstein-Barr Virus and/or Cytomegalovirus Leading to Hemophagocytic Syndrome in One of Two Patients. 61
29386835 2018
19
[Comprehensive evaluation and risk control measures of Xanthii Fructus]. 61
29271143 2017
20
Bevacizumab-associated Sudden Onset of Multiple Monomorphic Comedones on the Scalp Successfully Treated with 30% Salicylic Acid Peels. 61
29252179 2017
21
Severe cutaneous adverse drug reactions of Chinese inpatients: a meta-analysis. 61
29186246 2017
22
ADULT syndrome: dental features of a very rare condition. 61
28691455 2017
23
Imatinib mesylate-induced lichenoid drug eruption. 61
28398413 2017
24
Histological and parasitological distinctive findings in clinically-lesioned and normal-looking skin of dogs with different clinical stages of leishmaniosis. 61
28288670 2017
25
An exploratory factor analysis of the spontaneous reporting of severe cutaneous adverse reactions. 61
28203363 2017
26
Adverse reactions in leprosy patients who underwent dapsone multidrug therapy: a retrospective study. 61
28721106 2017
27
Intermediate Phenotype between ADULT Syndrome and EEC Syndrome Caused by R243Q Mutation in TP63. 61
28293528 2016
28
Eccrine Syringofibroadenoma in a Patient with Long-Standing Exfoliative Dermatitis. 61
27904279 2016
29
Slow desensitization of imatinib-induced nonimmediate reactions and dynamic changes of drug-specific CD4+CD25+CD134+ lymphocytes. 61
27788881 2016
30
Proposed ICDRG Classification of the Clinical Presentation of Contact Allergy. 61
27608064 2016
31
Seroprevalence of Canine Leishmaniasis in Northern Cyprus. 61
27905278 2016
32
Oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis. 61
27651712 2016
33
Erythrodermic Psoriasis Treated with Apremilast. 61
27942369 2016
34
Proton pump inhibitor-induced exfoliative dermatitis: A case report. 61
26893644 2016
35
Cutaneous Presentation of Angioimmunoblastic T-Cell Lymphoma: A Harbinger of Poor Prognosis? 61
28031140 2016
36
Drug induced exfoliative dermatitis: state of the art. 61
27551239 2016
37
Negative cutaneous effects of medicinal plants in Senegal. 61
26207662 2015
38
Lichenoid drug reaction to isoniazid presenting as exfoliative dermatitis in a patient with acquired immunodeficiency syndrome. 61
25013221 2015
39
Adverse cutaneous drug reactions--a clinico-demographic study in a tertiary care teaching hospital of the Kashmir Valley, India. 61
25841943 2015
40
Nonthymoma-associated exfoliative dermatitis in 18 cats. 61
25367344 2015
41
Cutaneous immune mechanisms in canine leishmaniosis due to Leishmania infantum. 61
25555497 2015
42
Ayurvedic management of life-threatening skin emergency erythroderma: A case study. 61
26730142 2015
43
Adverse events of anti-tumor necrosis factor α therapy in ankylosing spondylitis. 61
25764452 2015
44
Thymoma associated with exfoliative dermatitis in a cat. 61
24782458 2014
45
Cutaneous adverse drug reactions in Indian population: A systematic review. 61
25593813 2014
46
Erythroderma secondary to gliclazide: a case report. 61
24641117 2014
47
Identification of risk factors for carbamazepine-induced serious mucocutaneous adverse reactions: A case-control study using data from spontaneous adverse drug reaction reports. 61
24799813 2014
48
Prevalence of dermatological presentations of canine leishmaniasis in a nonendemic area: a retrospective study of 100 dogs. 61
24660088 2014
49
Occupational trichloroethylene hypersensitivity syndrome: human herpesvirus 6 reactivation and rash phenotypes. 61
23928230 2013
50
A rare case of imatinib-induced erythroderma. 61
24347779 2013

Variations for Exfoliative Dermatitis

Expression for Exfoliative Dermatitis

Search GEO for disease gene expression data for Exfoliative Dermatitis.

Pathways for Exfoliative Dermatitis

GO Terms for Exfoliative Dermatitis

Sources for Exfoliative Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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