MCID: EXP003
MIFTS: 16

Exophthalmic Ophthalmoplegia

Categories: Neuronal diseases

Aliases & Classifications for Exophthalmic Ophthalmoplegia

MalaCards integrated aliases for Exophthalmic Ophthalmoplegia:

Name: Exophthalmic Ophthalmoplegia 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:13135
ICD9CM 34 376.22
SNOMED-CT 67 69763009
UMLS 71 C0152135

Summaries for Exophthalmic Ophthalmoplegia

MalaCards based summary : Exophthalmic Ophthalmoplegia is related to graves disease 1 and kearns-sayre syndrome, and has symptoms including ophthalmoplegia An important gene associated with Exophthalmic Ophthalmoplegia is KCNJ18 (Potassium Inwardly Rectifying Channel Subfamily J Member 18). Affiliated tissues include thyroid and breast, and related phenotype is Synthetic lethal with c-Myc after tamoxifen stimulation.

Related Diseases for Exophthalmic Ophthalmoplegia

Diseases related to Exophthalmic Ophthalmoplegia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 graves disease 1 29.9 POMC KCNJ18
2 kearns-sayre syndrome 10.8
3 exophthalmos 10.3
4 vitiligo-associated multiple autoimmune disease susceptibility 6 10.1
5 myasthenia gravis 10.1
6 vitiligo-associated multiple autoimmune disease susceptibility 1 10.1
7 myopathy 10.1
8 muscular atrophy 10.1
9 myopathy - thyrotoxic 10.1
10 hypercholesterolemia, familial, 4 9.5 POMC BRD4
11 hypokalemia 9.3 POMC KCNJ18
12 hyperthyroidism 9.2 POMC KCNJ18

Graphical network of the top 20 diseases related to Exophthalmic Ophthalmoplegia:



Diseases related to Exophthalmic Ophthalmoplegia

Symptoms & Phenotypes for Exophthalmic Ophthalmoplegia

UMLS symptoms related to Exophthalmic Ophthalmoplegia:


ophthalmoplegia

GenomeRNAi Phenotypes related to Exophthalmic Ophthalmoplegia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with c-Myc after tamoxifen stimulation GR00215-A 8.62 BRD4 POMC

Drugs & Therapeutics for Exophthalmic Ophthalmoplegia

Search Clinical Trials , NIH Clinical Center for Exophthalmic Ophthalmoplegia

Genetic Tests for Exophthalmic Ophthalmoplegia

Anatomical Context for Exophthalmic Ophthalmoplegia

MalaCards organs/tissues related to Exophthalmic Ophthalmoplegia:

40
Thyroid, Breast

Publications for Exophthalmic Ophthalmoplegia

Articles related to Exophthalmic Ophthalmoplegia:

(show all 27)
# Title Authors PMID Year
1
Neuromuscular disorders in thyrotoxicosis. 61
6893387 1980
2
The surgery of exophthalmic ophthalmoplegia. 61
4190507 1969
3
Bilateral exophthalmic ophthalmoplegia. A case report. 61
5394300 1969
4
The orthoptic management of exophthalmic ophthalmoplegia. 61
5710894 1968
5
Exophthalmic ophthalmoplegia. 61
14477051 1962
6
Discrete carcinomatous metastases in the extrinsic ocular muscles. A case of carcinoma of the breast with exophthalmic ophthalmoplegia. 61
13798189 1960
7
Gross digital clubbing and exophthalmic ophthalmoplegia in thyroid disorders. 61
13564758 1958
8
The surgical treatment of exophthalmic ophthalmoplegia. 61
13394650 1957
9
Exophthalmic ophthalmoplegia: report of a case in which complete recovery followed x-irradiation of the orbit. 61
13390989 1956
10
Hyaluronidase in the treatment of exophthalmic ophthalmoplegia. 61
13252913 1955
11
CORTISONE in exophthalmos: report on a therapeutic trial of cortisone and corticotrophin (A.C.T.H.) in exophthalmos and exophthalmic ophthalmoplegia by a panel appointed by the Medical Research Council. 61
13222835 1955
12
Exophthalmic ophthalmoplegia supervening on spontaneous myxoedema. 61
13155536 1954
13
Cortisone and ACTH in exophthalmic ophthalmoplegia. 61
14918443 1952
14
Exophthalmic ophthalmoplegia with gross papilloedema. 61
14930045 1952
15
A further report on exophthalmic ophthalmoplegia and its relation to thyrotoxicosis. 61
14846860 1951
16
Exophthalmic ophthalmoplegia treated by operation. 61
14834180 1951
17
[Exophthalmic ophthalmoplegia]. 61
14882770 1951
18
Thyroidectomy and thyrotropic exophthalmos (exophthalmic ophthalmoplegia) a review of 1001 thyroidectomies. 61
15408010 1949
19
Thyrotoxicosis; exophthalmic ophthalmoplegia, myasthenia gravis and vitiligo. 61
18210580 1949
20
Exophthalmic ophthalmoplegia treated with prostigmin. 61
18914725 1948
21
Exophthalmic ophthalmoplegia and its relation to thyrotoxicosis. 61
20986517 1946
22
Exophthalmic Ophthalmoplegia (Unilateral) with Papilloedema. 61
19992417 1941
23
Exophthalmic Ophthalmoplegia (Unilateral) with Papillœdema. 61
20916814 1941
24
Two Cases of Exophthalmic Ophthalmoplegia. 61
19991916 1939
25
Unilateral Exophthalmic Ophthalmoplegia. 61
19991840 1939
26
Muscular Atrophy and Weakness in Thyrotoxicosis (Thyrotoxic Myopathy; Exophthalmic Ophthalmoplegia). 61
21407592 1939
27
A CASE OF "EXOPHTHALMIC OPHTHALMOPLEGIA WITH THYROTOXICOSIS". 61
18169401 1936

Variations for Exophthalmic Ophthalmoplegia

Expression for Exophthalmic Ophthalmoplegia

Search GEO for disease gene expression data for Exophthalmic Ophthalmoplegia.

Pathways for Exophthalmic Ophthalmoplegia

GO Terms for Exophthalmic Ophthalmoplegia

Sources for Exophthalmic Ophthalmoplegia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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