MCID: EXP001
MIFTS: 26

Expressive Language Disorder

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Expressive Language Disorder

MalaCards integrated aliases for Expressive Language Disorder:

Name: Expressive Language Disorder 12 15 33
Developmental Expressive Language Disorder 12 72

Classifications:



External Ids:

Disease Ontology 12 DOID:11385
ICD9CM 35 315.31
NCIt 50 C92562
SNOMED-CT 68 80360005
ICD10 33 F80.1
UMLS 72 C0236826

Summaries for Expressive Language Disorder

Disease Ontology : 12 A language disorder that involves difficulties with verbal and written expression characterized by an ability to use expressive spoken language that is markedly below the appropriate level for the mental age, but with a language comprehension that is within normal limits.

MalaCards based summary : Expressive Language Disorder, also known as developmental expressive language disorder, is related to mixed receptive-expressive language disorder and dysphasia, familial developmental. An important gene associated with Expressive Language Disorder is SLC6A8 (Solute Carrier Family 6 Member 8). Affiliated tissues include brain, heart and testes, and related phenotype is pigmentation.

Wikipedia : 75 Expressive language disorder is a communication disorder in which there are difficulties with verbal and... more...

Related Diseases for Expressive Language Disorder

Diseases related to Expressive Language Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 mixed receptive-expressive language disorder 12.9
2 dysphasia, familial developmental 10.6
3 speech and communication disorders 10.1
4 autism 9.8
5 apraxia 9.8
6 articulation disorder 9.8
7 specific developmental disorder 9.7 SLC6A8 FOXP2

Comorbidity relations with Expressive Language Disorder via Phenotypic Disease Network (PDN):


Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation

Graphical network of the top 20 diseases related to Expressive Language Disorder:



Diseases related to Expressive Language Disorder

Symptoms & Phenotypes for Expressive Language Disorder

MGI Mouse Phenotypes related to Expressive Language Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 pigmentation MP:0001186 8.8 NF1 PPT1 SLC6A8

Drugs & Therapeutics for Expressive Language Disorder

Search Clinical Trials , NIH Clinical Center for Expressive Language Disorder

Genetic Tests for Expressive Language Disorder

Anatomical Context for Expressive Language Disorder

MalaCards organs/tissues related to Expressive Language Disorder:

41
Brain, Heart, Testes

Publications for Expressive Language Disorder

Articles related to Expressive Language Disorder:

(show all 47)
# Title Authors PMID Year
1
Cognitive profile and disorders affecting higher brain functions in paediatric patients with neurofibromatosis type 1. 38
28431841 2019
2
Children screening positive for language delay at 2.5 years: language disorder and developmental profiles. 38
30568449 2018
3
Adaptation, validity, and reliability of the Preschool Language Scale-Fifth Edition (PLS-5) in the Turkish context: The Turkish Preschool Language Scale-5 (TPLS-5). 38
28583491 2017
4
FOXP2-Related Speech and Language Disorders 38
27336128 2016
5
Expanding the phenotypic profile of Kleefstra syndrome: A female with low-average intelligence and childhood apraxia of speech. 38
26833960 2016
6
Comorbidity of fetal alcohol spectrum disorder: a systematic review and meta-analysis. 38
26777270 2016
7
Sensorimotor function in preschool-aged children with expressive language disorder. 38
24685939 2014
8
Health related quality of life in parents of children with speech and hearing impairment. 38
24388315 2014
9
Small intragenic deletion in FOXP2 associated with childhood apraxia of speech and dysarthria. 38
23918746 2013
10
[Abnormal electroencephalography results and specific language impairment: towards a theoretical neurodevelopmental model?]. 38
22980473 2012
11
The validity of psychiatric diagnoses: the case of 'specific' developmental disorders. 38
21705192 2011
12
Children with 7q11.23 Duplication Syndrome: Speech, Language, Cognitive, and Behavioral Characteristics and their Implications for Intervention. 38
22754604 2011
13
The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene. 38
21424531 2011
14
Speech and language delay in children. 38
21568252 2011
15
Role of assessment tests in the stability of intelligence scoring of pre-school children with uneven/delayed cognitive profile. 38
21375639 2011
16
[Expressive language disorder and focal paroxysmal activity]. 38
21365595 2011
17
Landau-Kleffner syndrome: a rare auditory processing disorder series of cases and review of the literature. 38
21074868 2011
18
How to distinguish normal from disordered children with poor language or motor skills. 38
20144011 2010
19
Ian: a 7-year old with prenatal drug exposure and early exposure to family violence. 38
20414070 2010
20
Is expressive language disorder an accurate diagnostic category? 38
19029534 2009
21
A longitudinal study of personality disorders in individuals with and without a history of developmental language disorder. 38
19626542 2009
22
Children with mixed language disorder do not discriminate accurately facial identity when expressions change. 38
18427859 2008
23
Ian: a 7-year old with prenatal drug exposure and early exposure to family violence. 38
19077846 2008
24
A longitudinal study of schizophrenia- and affective spectrum disorders in individuals diagnosed with a developmental language disorder as children. 38
18818864 2008
25
Using a speech-generating device to enhance communicative abilities for an adult with moderate intellectual disability. 38
19090639 2008
26
Correlates of language impairment in children with galactosaemia. 38
18649009 2008
27
Can autism, language and coordination disorders be differentiated based on ability profiles? 38
17136301 2007
28
Epidemiological study of child & adolescent psychiatric disorders in urban & rural areas of Bangalore, India. 38
16106093 2005
29
[Specific language disorders: their diagnosis, classification and study using magnetoencephalography]. 38
15736073 2005
30
[Concerning specific language impairment: intelligibility in expressive language]. 38
15284946 2004
31
Presence of normal creatine in the muscle of a patient with a mutation in the creatine transporter: a case study. 38
15532707 2004
32
Comparative study of early childhood high-function autism and developmental mixed receptive-expressive language disorder. 38
15481561 2004
33
Co-morbidity and treatment of attention deficit hyperactivity disorder in Saudi Arabia. 38
16450529 2003
34
[Expressive language disorder]. 38
14503321 2003
35
Evaluation of neuromotor deficits in children with autism and children with a specific speech and language disorder. 38
12469239 2002
36
Clinical implications of a link between fetal alcohol spectrum disorder and attention-deficit hyperactivity disorder. 38
12025433 2002
37
[Behavioral problems in children with specific and pervasive developmental disorders, evaluated with the psychopathology assessment scale (AMDP)]. 38
11721613 2001
38
Gabapentin and methylphenidate treatment of a preadolescent with attention deficit hyperactivity disorder and bipolar disorder. 38
11642481 2001
39
Diagnostic assessment of communicative and interactive behaviours in children with autism and receptive language disorder. 38
11202105 2000
40
Expressive language disorder after infarction of left lentiform nucleus. 38
10942673 2000
41
The influence of premorbid language skills and behavior on language recovery in children with verbal auditory agnosia. 38
10641609 2000
42
Genetic studies of autistic disorder and chromosome 7. 38
10552924 1999
43
Evaluation and management of the child with speech delay. 38
10392594 1999
44
Subtyping stereotypic behavior in children: the association between stereotypic behavior, mood, and heart rate. 38
9932241 1998
45
The effect of a diagnostic label of language delay on adults' perceptions of preschool children. 38
8942302 1996
46
Behavioral correlates of developmental expressive language disorder. 38
2745899 1989
47
Language growth in children with expressive language delay. 38
2913552 1989

Variations for Expressive Language Disorder

Expression for Expressive Language Disorder

Search GEO for disease gene expression data for Expressive Language Disorder.

Pathways for Expressive Language Disorder

GO Terms for Expressive Language Disorder

Cellular components related to Expressive Language Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 dendrite GO:0030425 8.8 PPT1 NF1 FUS

Biological processes related to Expressive Language Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cerebral cortex development GO:0021987 9.16 NF1 FOXP2
2 skeletal muscle tissue development GO:0007519 8.96 NF1 FOXP2
3 smooth muscle tissue development GO:0048745 8.62 NF1 FOXP2

Sources for Expressive Language Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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