MCID: EXT056
MIFTS: 20

External Ear Disease

Categories: Ear diseases

Aliases & Classifications for External Ear Disease

MalaCards integrated aliases for External Ear Disease:

Name: External Ear Disease 12 15 17
Preauricular Cyst 12 74
Preauricular Sinus and Fistula 12
Preauricular Sinus or Fistula 12
Diseases of External Ear 74

Classifications:



External Ids:

Disease Ontology 12 DOID:379
ICD9CM 36 380 380.9
NCIt 51 C26972
SNOMED-CT 69 49130001

Summaries for External Ear Disease

MalaCards based summary : External Ear Disease, also known as preauricular cyst, is related to otitis externa and cholesteatoma of middle ear. An important gene associated with External Ear Disease is MTFMT (Mitochondrial Methionyl-TRNA Formyltransferase).

Related Diseases for External Ear Disease

Diseases related to External Ear Disease via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 otitis externa 31.3 DOCK8 MTFMT
2 cholesteatoma of middle ear 9.9
3 coccidioidomycosis 9.9
4 facial paralysis 9.9
5 auditory system disease 9.8

Graphical network of the top 20 diseases related to External Ear Disease:



Diseases related to External Ear Disease

Symptoms & Phenotypes for External Ear Disease

Drugs & Therapeutics for External Ear Disease

Search Clinical Trials , NIH Clinical Center for External Ear Disease

Genetic Tests for External Ear Disease

Anatomical Context for External Ear Disease

Publications for External Ear Disease

Articles related to External Ear Disease:

# Title Authors Year
1
Primary Cutaneous Coccidioidomycosis Presenting as a Recurrent Preauricular Cyst. ( 27319963 )
2016
2
Preauricular cyst associated with congenital cholesteatoma: an unusual cause of facial palsy. ( 8172317 )
1994

Variations for External Ear Disease

Expression for External Ear Disease

Search GEO for disease gene expression data for External Ear Disease.

Pathways for External Ear Disease

GO Terms for External Ear Disease

Biological processes related to External Ear Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.26 BCL10 MTDH
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.16 BCL10 MTDH
3 translational initiation GO:0006413 8.96 MTFMT RPS19
4 lipopolysaccharide-mediated signaling pathway GO:0031663 8.62 BCL10 MTDH

Molecular functions related to External Ear Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NF-kappaB binding GO:0051059 8.62 BCL10 MTDH

Sources for External Ear Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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